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Arun Upadhyay, Ph.D., M.Sc., B.Sc. - Publications

Affiliations: 
Neurology Northwestern University, Evanston, IL 
Area:
Neurodegeneration, Amyloids, Protein Degradation, Ubiquitin, Autophagy, Apoptosis, Ubiquitin Proteasome system, Alzheimer's disease
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rao NR, Upadhyay A, Savas JN. Derailed protein turnover in the aging mammalian brain. Molecular Systems Biology. PMID 38182797 DOI: 10.1038/s44320-023-00009-2  0.624
2023 Upadhyay A, Chhangani D, Rao NR, Kofler J, Vassar R, Rincon-Limas DE, Savas JN. Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity. Molecular Neurodegeneration. 18: 61. PMID 37710351 DOI: 10.1186/s13024-023-00654-z  0.771
2023 Singh S, Joshi V, Upadhyay A. Amyloids and Brain Cancer: molecular linkages and crossovers. Bioscience Reports. PMID 37335084 DOI: 10.1042/BSR20230489  0.636
2022 Amanullah A, Upadhyay A, Dhiman R, Singh S, Kumar A, Ahirwar DK, Gutti RK, Mishra A. Development and Challenges of Diclofenac-Based Novel Therapeutics: Targeting Cancer and Complex Diseases. Cancers. 14. PMID 36139546 DOI: 10.3390/cancers14184385  0.497
2022 Upadhyay A, Vassar RJ, Savas JN. Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain. Journal of Visualized Experiments : Jove. PMID 35575522 DOI: 10.3791/63816  0.726
2021 Upadhyay A. Natural compounds in the regulation of proteostatic pathways: An invincible artillery against stress, ageing, and diseases. Acta Pharmaceutica Sinica. B. 11: 2995-3014. PMID 34729300 DOI: 10.1016/j.apsb.2021.01.006  0.478
2021 Sundaria N, Upadhyay A, Prasad A, Prajapati VK, Poluri KM, Mishra A. Neurodegeneration & Imperfect Ageing: Technological Limitations and Challenges? Mechanisms of Ageing and Development. 111574. PMID 34562507 DOI: 10.1016/j.mad.2021.111574  0.596
2021 Jakhmola S, Upadhyay A, Jain K, Mishra A, Jha HC. Herpesviruses and the hidden links to Multiple Sclerosis neuropathology. Journal of Neuroimmunology. 358: 577636. PMID 34174587 DOI: 10.1016/j.jneuroim.2021.577636  0.435
2021 Upadhyay A, Amanullah A, Joshi V, Dhiman R, Prajapati VK, Poluri KM, Mishra A. Ibuprofen-based advanced therapeutics: breaking the inflammatory link in cancer, neurodegeneration, and diseases. Drug Metabolism Reviews. 1-22. PMID 33820460 DOI: 10.1080/03602532.2021.1903488  0.683
2021 Upadhyay A, Sundaria N, Dhiman R, Prajapati VK, Prasad A, Mishra A. Complex Inclusion Bodies and Defective Proteome Hubs in Neurodegenerative Disease: New Clues, New Challenges. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858421989582. PMID 33530848 DOI: 10.1177/1073858421989582  0.623
2021 Prasanna P, Kumar R, Singh VK, Upadhyay A. Cloning, purification, and homology modeling of Histone deacetylase in Leishmania donovani. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 104738. PMID 33516971 DOI: 10.1016/j.meegid.2021.104738  0.33
2020 Hark TJ, Rao NR, Castillon C, Basta T, Smukowski S, Bao H, Upadhyay A, Bomba-Warczak E, Nomura T, O'Toole ET, Morgan GP, Ali L, Saito T, Guillermier C, Saido TC, et al. Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals. Cell Systems. PMID 33326751 DOI: 10.1016/j.cels.2020.11.007  0.792
2020 Mishra R, Joshi V, Upadhyay A, Amanullah A, Dubey AR, Singh S, Dubey VK, Poluri KM, Jana NR, Mishra A. LRSAM1 E3 ubiquitin ligase promotes proteasomal clearance of E6-AP protein. Cellular Signalling. 77: 109836. PMID 33207262 DOI: 10.1016/j.cellsig.2020.109836  0.818
2020 Graykowski DR, Wang YZ, Upadhyay A, Savas JN. The Dichotomous Role of Extracellular Vesicles in the Central Nervous System. Iscience. 23: 101456. PMID 32835924 DOI: 10.1016/J.Isci.2020.101456  0.681
2020 Joshi V, Upadhyay A, Prajapati VK, Mishra A. How autophagy can restore proteostasis defects in multiple diseases? Medicinal Research Reviews. PMID 32043639 DOI: 10.1002/Med.21662  0.775
2020 Mishra R, Amanullah A, Upadhyay A, Dhiman R, Dubey AR, Singh S, Prasad A, Mishra A. Ubiquitin Ligase LRSAM1 Suppresses Neurodegenerative Diseases Linked Aberrant Proteins Induced Cell Death. The International Journal of Biochemistry & Cell Biology. 105697. PMID 31982566 DOI: 10.1016/J.Biocel.2020.105697  0.808
2020 Upadhyay A. Cancer: An Unknown Territory; Rethinking Before Going Ahead Genes and Diseases. DOI: 10.1016/J.Gendis.2020.09.002  0.382
2019 Upadhyay A. Structure of proteins: Evolution with unsolved mysteries. Progress in Biophysics and Molecular Biology. PMID 31014967 DOI: 10.1016/J.Pbiomolbio.2019.04.007  0.42
2019 Joshi V, Mishra R, Upadhyay A, Amanullah A, Poluri KM, Singh S, Kumar A, Mishra A. Polyphenolic flavonoid (Myricetin) upregulated proteasomal degradation mechanisms: Eliminates neurodegenerative proteins aggregation. Journal of Cellular Physiology. PMID 31004355 DOI: 10.1002/Jcp.28695  0.838
2019 Mishra R, Upadhyay A, Prajapati VK, Dhiman R, Poluri KM, Jana NR, Mishra A. LRSAM1 E3 ubiquitin ligase: molecular neurobiological perspectives linked with brain diseases. Cellular and Molecular Life Sciences : Cmls. PMID 30826859 DOI: 10.1007/S00018-019-03055-Y  0.831
2019 Sherine J, Upadhyay A, Mishra A, Kumar D, Pal S, Harinipriya S. Ag(I) and Au(III) Mercaptobenzothiazole complexes induced apoptotic cell death. Scientific Reports. 9: 621. PMID 30679607 DOI: 10.1038/S41598-018-36801-6  0.506
2018 Joshi V, Upadhyay A, Chhangani D, Amanullah A, Sharan RN, Mishra A. Gp78 involvement in cellular proliferation: Can act as a promising modulator for cell cycle regulatory proteins? Journal of Cellular Physiology. PMID 29741771 DOI: 10.1002/Jcp.26618  0.801
2018 Mishra R, Upadhyay A, Prajapati VK, Mishra A. Proteasome-mediated proteostasis: Novel medicinal and pharmacological strategies for diseases. Medicinal Research Reviews. PMID 29719055 DOI: 10.1002/Med.21502  0.793
2018 Upadhyay A, Mishra A. Amyloids of multiple species: are they helpful in survival? Biological Reviews of the Cambridge Philosophical Society. PMID 29436097 DOI: 10.1111/Brv.12399  0.653
2017 Khan E, Tawani A, Mishra SK, Verma AK, Upadhyay A, Kumar M, Sandhir R, Mishra A, Kumar A. Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs). Acs Chemical Biology. PMID 29172480 DOI: 10.1021/Acschembio.7B00699  0.547
2017 Joshi V, Upadhyay A, Kumar A, Mishra A. Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis. Frontiers in Cellular Neuroscience. 11: 259. PMID 28890687 DOI: 10.3389/Fncel.2017.00259  0.783
2017 Amanullah A, Upadhyay A, Joshi V, Mishra R, Jana NR, Mishra A. Progressing Neurobiological Strategies Against Proteostasis Failure: Challenges in Neurodegeneration. Progress in Neurobiology. PMID 28870769 DOI: 10.1016/J.Pneurobio.2017.08.005  0.822
2017 Amanullah A, Mishra R, Upadhyay A, Reddy PP, Das R, Mishra A. Indomethacin Elicits Proteasomal Dysfunctions Develops Apoptosis Through Mitochondrial Abnormalities. Journal of Cellular Physiology. PMID 28681929 DOI: 10.1002/Jcp.26081  0.732
2017 Upadhyay A, Joshi V, Amanullah A, Mishra R, Arora N, Prasad A, Mishra A. E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to Degeneration. Frontiers in Molecular Neuroscience. 10: 151. PMID 28579943 DOI: 10.3389/Fnmol.2017.00151  0.827
2017 Upadhyay A, Amanullah A, Mishra R, Kumar A, Mishra A. Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases. Molecular Neurobiology. PMID 28102469 DOI: 10.1007/S12035-016-0377-2  0.791
2016 Joshi V, Amanullah A, Upadhyay A, Mishra R, Kumar A, Mishra A. A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging? Frontiers in Molecular Neuroscience. 9: 93. PMID 27757073 DOI: 10.3389/Fnmol.2016.00093  0.831
2016 Amanullah A, Upadhyay A, Chhangani D, Joshi V, Mishra R, Yamanaka K, Mishra A. Proteasomal Dysfunction Induced by Diclofenac Engenders Apoptosis through Mitochondrial Pathway. Journal of Cellular Biochemistry. PMID 27487200 DOI: 10.1002/Jcb.25666  0.779
2015 Upadhyay A, Amanullah A, Chhangani D, Joshi V, Mishra R, Mishra A. Ibuprofen Induces Mitochondrial-Mediated Apoptosis Through Proteasomal Dysfunction. Molecular Neurobiology. PMID 26666667 DOI: 10.1007/S12035-015-9603-6  0.772
2015 Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A. Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model. Neurobiology of Disease. PMID 26607786 DOI: 10.1016/J.Nbd.2015.11.017  0.797
2015 Upadhyay A, Amanullah A, Chhangani D, Mishra R, Prasad A, Mishra A. Mahogunin Ring Finger-1 (MGRN1), a Multifaceted Ubiquitin Ligase: Recent Unraveling of Neurobiological Mechanisms. Molecular Neurobiology. PMID 26255182 DOI: 10.1007/S12035-015-9379-8  0.827
2015 Upadhyay A, Amanullah A, Chhangani D, Mishra R, Mishra A. Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing. Ageing Research Reviews. PMID 26247845 DOI: 10.1016/J.Arr.2015.07.009  0.809
2015 Singh A, Upadhyay V, Upadhyay AK, Singh SM, Panda AK. Protein recovery from inclusion bodies of Escherichia coli using mild solubilization process. Microbial Cell Factories. 14: 41. PMID 25889252 DOI: 10.1186/s12934-015-0222-8  0.347
2015 Upadhyay A, Amanullah A, Chhangani D, Mishra R, Prasad A, Mishra A. Mahogunin Ring Finger-1 (MGRN1), a Multifaceted Ubiquitin Ligase: Recent Unraveling of Neurobiological Mechanisms Molecular Neurobiology. DOI: 10.1007/s12035-015-9379-8  0.771
2014 Chhangani D, Upadhyay A, Amanullah A, Joshi V, Mishra A. Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins. Scientific Reports. 4: 5077. PMID 24865853 DOI: 10.1038/Srep05077  0.835
2014 Chhangani D, Nukina N, Kurosawa M, Amanullah A, Joshi V, Upadhyay A, Mishra A. Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity. Biochimica Et Biophysica Acta. 1842: 1472-84. PMID 24769000 DOI: 10.1016/J.Bbadis.2014.04.014  0.827
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