Richard I Gregory - Publications

Affiliations: 
Children's Hospital Boston Harvard Medical School, Boston, MA, United States 

69/138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Orellana EA, Siegal E, Gregory RI. tRNA dysregulation and disease. Nature Reviews. Genetics. PMID 35681060 DOI: 10.1038/s41576-022-00501-9  0.321
2021 Cui Y, Lyu X, Ding L, Ke L, Yang D, Pirouz M, Qi Y, Ong J, Gao G, Du P, Gregory RI. Global miRNA dosage control of embryonic germ layer specification. Nature. PMID 33953397 DOI: 10.1038/s41586-021-03524-0  0.406
2020 Foster DJ, Chang HM, Haswell JR, Gregory RI, Slack FJ. TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs. Cell Cycle (Georgetown, Tex.). 1-13. PMID 32816599 DOI: 10.1080/15384101.2020.1804232  0.374
2020 Pirouz M, Wang CH, Liu Q, Ebrahimi AG, Shamsi F, Tseng YH, Gregory RI. The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis. Nature Communications. 11: 2619. PMID 32457326 DOI: 10.1038/S41467-020-16418-Y  0.38
2020 Liu Q, Shvarts T, Sliz P, Gregory RI. RiboToolkit: an integrated platform for analysis and annotation of ribosome profiling data to decode mRNA translation at codon resolution. Nucleic Acids Research. PMID 32427338 DOI: 10.1093/Nar/Gkaa395  0.311
2020 Chen H, Gu L, Orellana EA, Wang Y, Guo J, Liu Q, Wang L, Shen Z, Wu H, Gregory RI, Xing Y, Shi Y. METTL4 is an snRNA mAm methyltransferase that regulates RNA splicing. Cell Research. PMID 31913360 DOI: 10.1038/S41422-019-0270-4  0.364
2019 Lin S, Liu Q, Jiang YZ, Gregory RI. Nucleotide resolution profiling of mG tRNA modification by TRAC-Seq. Nature Protocols. PMID 31619810 DOI: 10.1038/S41596-019-0226-7  0.335
2019 Pirouz M, Munafò M, Ebrahimi AG, Choe J, Gregory RI. Exonuclease requirements for mammalian ribosomal RNA biogenesis and surveillance. Nature Structural & Molecular Biology. PMID 31160785 DOI: 10.1038/S41594-019-0234-X  0.374
2019 Liu Q, Gregory RI. RNAmod: an integrated system for the annotation of mRNA modifications. Nucleic Acids Research. PMID 31147718 DOI: 10.1093/Nar/Gkz479  0.382
2019 Paris J, Morgan M, Campos J, Spencer GJ, Shmakova A, Ivanova I, Mapperley C, Lawson H, Wotherspoon DA, Sepulveda C, Vukovic M, Allen L, Sarapuu A, Tavosanis A, Guitart AV, ... ... Gregory RI, et al. Targeting the RNA mA Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia. Cell Stem Cell. PMID 31031138 DOI: 10.1016/J.Stem.2019.03.021  0.407
2018 Pirouz M, Ebrahimi AG, Gregory RI. Unraveling 3'-end RNA uridylation at nucleotide resolution. Methods (San Diego, Calif.). PMID 30395968 DOI: 10.1016/J.Ymeth.2018.10.024  0.4
2018 Choe J, Lin S, Zhang W, Liu Q, Wang L, Ramirez-Moya J, Du P, Kim W, Tang S, Sliz P, Santisteban P, George RE, Richards WG, Wong KK, Locker N, ... ... Gregory RI, et al. mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. Nature. PMID 30232453 DOI: 10.1038/S41586-018-0538-8  0.388
2018 Park HH, Triboulet R, Bentler M, Guda S, Du P, Xu H, Gregory RI, Brendel C, Williams DA. DROSHA Knockout Leads to Enhancement of Viral Titers for Vectors Encoding miRNA-Adapted shRNAs. Molecular Therapy. Nucleic Acids. 12: 591-599. PMID 30195795 DOI: 10.1016/J.Omtn.2018.07.002  0.424
2018 Lin S, Liu Q, Lelyveld VS, Choe J, Szostak JW, Gregory RI. Mettl1/Wdr4-Mediated mG tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation. Molecular Cell. PMID 29983320 DOI: 10.1016/J.Molcel.2018.06.001  0.364
2018 Du P, Pirouz M, Choi J, Huebner AJ, Clement K, Meissner A, Hochedlinger K, Gregory RI. An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition. Cell Stem Cell. PMID 29804889 DOI: 10.1016/J.Stem.2018.04.021  0.474
2018 Ogórek B, Lam HC, Khabibullin D, Liu HJ, Nijmeh J, Triboulet R, Kwiatkowski DJ, Gregory RI, Henske EP. TSC2 Regulates microRNA Biogenesis via mTORC1 and GSK3β. Human Molecular Genetics. PMID 29509898 DOI: 10.1093/Hmg/Ddy073  0.423
2017 Cinkornpumin J, Roos M, Nguyen L, Liu X, Gaeta X, Lin S, Chan DN, Liu A, Gregory RI, Jung M, Chute J, Zhu H, Lowry WE. A small molecule screen to identify regulators of let-7 targets. Scientific Reports. 7: 15973. PMID 29162914 DOI: 10.1038/S41598-017-16258-9  0.429
2016 Tsanov KM, Pearson DS, Wu Z, Han A, Triboulet R, Seligson MT, Powers JT, Osborne JK, Kane S, Gygi SP, Gregory RI, Daley GQ. LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency. Nature Cell Biology. PMID 27992407 DOI: 10.1038/Ncb3453  0.444
2016 Brendel C, Guda S, Renella R, Bauer DE, Canver MC, Kim YJ, Heeney MM, Klatt D, Fogel J, Milsom MD, Orkin SH, Gregory RI, Williams DA. Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype. The Journal of Clinical Investigation. 126: 3868-3878. PMID 27599293 DOI: 10.1172/Jci87885  0.409
2016 Pirouz M, Du P, Munafò M, Gregory RI. Dis3l2-Mediated Decay Is a Quality Control Pathway for Noncoding RNAs. Cell Reports. PMID 27498873 DOI: 10.1016/J.Celrep.2016.07.025  0.418
2016 Lin S, Choe J, Du P, Triboulet R, Gregory RI. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Molecular Cell. PMID 27117702 DOI: 10.1016/J.Molcel.2016.03.021  0.367
2016 Brendel C, Guda S, Renella R, Bauer DE, Canver MC, Kim Y, Heeney MM, Klatt D, Fogel J, Milsom MD, Orkin SH, Gregory RI, Williams DA. 282. Circumventing Hematopoietic Toxicities and Reversing Sickle Phenotype by Lineage-Specific BCL11A Knock Down and γ-Globin Induction Molecular Therapy. 24: S113. DOI: 10.1016/S1525-0016(16)33091-X  0.413
2015 Triboulet R, Pirouz M, Gregory RI. A Single Let-7 MicroRNA Bypasses LIN28-Mediated Repression. Cell Reports. 13: 260-6. PMID 26440890 DOI: 10.1016/J.Celrep.2015.08.086  0.541
2015 Das PP, Hendrix DA, Apostolou E, Buchner AH, Canver MC, Beyaz S, Ljuboja D, Kuintzle R, Kim W, Karnik R, Shao Z, Xie H, Xu J, De Los Angeles A, Zhang Y, ... ... Gregory RI, et al. PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells. Cell Reports. 12: 1456-1470. PMID 26299972 DOI: 10.1016/J.Celrep.2015.07.053  0.439
2015 Du P, Wang L, Sliz P, Gregory RI. A Biogenesis Step Upstream of Microprocessor Controls miR-17∼92 Expression. Cell. 162: 885-99. PMID 26255770 DOI: 10.1016/J.Cell.2015.07.008  0.426
2015 Lin S, Gregory RI. Identification of small molecule inhibitors of Zcchc11 TUTase activity. Rna Biology. 12: 792-800. PMID 26114892 DOI: 10.1080/15476286.2015.1058478  0.468
2015 Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, et al. miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1465-74. PMID 26080908 DOI: 10.1038/Mt.2015.113  0.487
2015 Lin S, Gregory RI. MicroRNA biogenesis pathways in cancer. Nature Reviews. Cancer. 15: 321-33. PMID 25998712 DOI: 10.1038/Nrc3932  0.425
2014 Thornton JE, Du P, Jing L, Sjekloca L, Lin S, Grossi E, Sliz P, Zon LI, Gregory RI. Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic Acids Research. 42: 11777-91. PMID 25223788 DOI: 10.1093/Nar/Gku805  0.49
2014 Mori M, Triboulet R, Mohseni M, Schlegelmilch K, Shrestha K, Camargo FD, Gregory RI. Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer. Cell. 156: 893-906. PMID 24581491 DOI: 10.1016/J.Cell.2013.12.043  0.489
2014 Lin S, Gregory RI. Methyltransferases modulate RNA stability in embryonic stem cells. Nature Cell Biology. 16: 129-31. PMID 24481042 DOI: 10.1038/Ncb2914  0.404
2014 Brendel C, Guda S, Renella R, Du P, Bauer DE, Canver MC, Kamran SC, Thornton J, de Boer H, Milsom MD, Orkin SH, Gregory R, Williams DA. Optimization of Bcl11a Knockdown By miRNA Scaffold Embedded Shrnas Leading to Enhanced Induction of Fetal Hemoglobin in Erythroid Cells for the Treatment of Beta-Hemoglobinopathies Blood. 124: 2150-2150. DOI: 10.1182/Blood.V124.21.2150.2150  0.455
2013 Kallen AN, Zhou XB, Xu J, Qiao C, Ma J, Yan L, Lu L, Liu C, Yi JS, Zhang H, Min W, Bennett AM, Gregory RI, Ding Y, Huang Y. The imprinted H19 lncRNA antagonizes let-7 microRNAs. Molecular Cell. 52: 101-12. PMID 24055342 DOI: 10.1016/J.Molcel.2013.08.027  0.371
2013 Martinez NJ, Chang HM, Borrajo Jde R, Gregory RI. The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly. Rna (New York, N.Y.). 19: 1583-93. PMID 24049110 DOI: 10.1261/Rna.040790.113  0.539
2013 Chang HM, Triboulet R, Thornton JE, Gregory RI. A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature. 497: 244-8. PMID 23594738 DOI: 10.1038/nature12119  0.391
2013 Martinez NJ, Gregory RI. Argonaute2 expression is post-transcriptionally coupled to microRNA abundance. Rna (New York, N.Y.). 19: 605-12. PMID 23485552 DOI: 10.1261/Rna.036434.112  0.542
2013 Shinoda G, De Soysa TY, Seligson MT, Yabuuchi A, Fujiwara Y, Huang PY, Hagan JP, Gregory RI, Moss EG, Daley GQ. Lin28a regulates germ cell pool size and fertility. Stem Cells (Dayton, Ohio). 31: 1001-9. PMID 23378032 DOI: 10.1002/Stem.1343  0.353
2012 Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, et al. EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science (New York, N.Y.). 338: 1465-9. PMID 23239736 DOI: 10.1126/Science.1227604  0.343
2012 Silveira-Neto AP, Leal LF, Emerman AB, Henderson KD, Piskounova E, Henderson BE, Gregory RI, Silveira LF, Hirschhorn JN, Nguyen TT, Beneduzzi D, Tusset C, Reis AC, Brito VN, Mendonca BB, et al. Absence of functional LIN28B mutations in a large cohort of patients with idiopathic central precocious puberty. Hormone Research in Pã¦Diatrics. 78: 144-50. PMID 22964795 DOI: 10.1159/000342212  0.678
2012 Thornton JE, Chang HM, Piskounova E, Gregory RI. Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7). Rna (New York, N.Y.). 18: 1875-85. PMID 22898984 DOI: 10.1261/Rna.034538.112  0.724
2012 Thornton JE, Gregory RI. How does Lin28 let-7 control development and disease? Trends in Cell Biology. 22: 474-82. PMID 22784697 DOI: 10.1016/J.Tcb.2012.06.001  0.499
2012 Chang HM, Martinez NJ, Thornton JE, Hagan JP, Nguyen KD, Gregory RI. Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation. Nature Communications. 3: 923. PMID 22735451 DOI: 10.1038/Ncomms1909  0.44
2011 Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell. 147: 1066-79. PMID 22118463 DOI: 10.1016/J.Cell.2011.10.039  0.69
2011 Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P. Molecular basis for interaction of let-7 microRNAs with Lin28. Cell. 147: 1080-91. PMID 22078496 DOI: 10.1016/J.Cell.2011.10.020  0.517
2011 Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI, et al. The Lin28/let-7 axis regulates glucose metabolism. Cell. 147: 81-94. PMID 21962509 DOI: 10.1016/J.Cell.2011.08.033  0.305
2011 Triboulet R, Gregory RI. Autoregulatory mechanisms controlling the microprocessor. Advances in Experimental Medicine and Biology. 700: 56-66. PMID 21755473 DOI: 10.1007/978-1-4419-7823-3_6  0.513
2011 Chang HM, Gregory RI. MicroRNAs and reprogramming. Nature Biotechnology. 29: 499-500. PMID 21654668 DOI: 10.1038/Nbt.1889  0.392
2011 Basu U, Meng FL, Keim C, Grinstein V, Pefanis E, Eccleston J, Zhang T, Myers D, Wasserman CR, Wesemann DR, Januszyk K, Gregory RI, Deng H, Lima CD, Alt FW. The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell. 144: 353-63. PMID 21255825 DOI: 10.1016/J.Cell.2011.01.001  0.353
2011 Suk K, Choi J, Suzuki Y, Ozturk SB, Mellor JC, Wong KH, MacKay JL, Gregory RI, Roth FP. Reconstitution of human RNA interference in budding yeast. Nucleic Acids Research. 39: e43. PMID 21252293 DOI: 10.1093/Nar/Gkq1321  0.37
2010 Triboulet R, Gregory RI. Autoregulatory mechanisms controlling the Microprocessor. Advances in Experimental Medicine and Biology. 700: 56-66. PMID 21627030  0.425
2010 Triboulet R, Gregory RI. Pumilio turns on microRNA function. Nature Cell Biology. 12: 928-9. PMID 20885420 DOI: 10.1038/Ncb1010-928  0.456
2010 Martinez NJ, Gregory RI. MicroRNA gene regulatory pathways in the establishment and maintenance of ESC identity. Cell Stem Cell. 7: 31-5. PMID 20621047 DOI: 10.1016/J.Stem.2010.06.011  0.448
2009 Hagan JP, Piskounova E, Gregory RI. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nature Structural & Molecular Biology. 16: 1021-5. PMID 19713958 DOI: 10.1038/Nsmb.1676  0.753
2009 Triboulet R, Chang HM, Lapierre RJ, Gregory RI. Post-transcriptional control of DGCR8 expression by the Microprocessor. Rna (New York, N.Y.). 15: 1005-11. PMID 19383765 DOI: 10.1261/Rna.1591709  0.519
2009 Winter J, Jung S, Keller S, Gregory RI, Diederichs S. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nature Cell Biology. 11: 228-34. PMID 19255566 DOI: 10.1038/Ncb0309-228  0.482
2009 Gregory RI, Khosla S, Feil R. Probing chromatin structure with nuclease sensitivity assays. Methods in Molecular Biology (Clifton, N.J.). 181: 269-84. PMID 12843457 DOI: 10.1385/1-59259-211-2:269  0.311
2008 Ho J, Ng KH, Rosen S, Dostal A, Gregory RI, Kreidberg JA. Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. Journal of the American Society of Nephrology : Jasn. 19: 2069-75. PMID 18832437 DOI: 10.1681/Asn.2008020162  0.477
2008 Piskounova E, Viswanathan SR, Janas M, LaPierre RJ, Daley GQ, Sliz P, Gregory RI. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. The Journal of Biological Chemistry. 283: 21310-4. PMID 18550544 DOI: 10.1074/Jbc.C800108200  0.739
2008 Faber J, Gregory RI, Armstrong SA. Linking miRNA regulation to BCR-ABL expression: the next dimension. Cancer Cell. 13: 467-9. PMID 18538729 DOI: 10.1016/J.Ccr.2008.05.013  0.4
2008 Li Q, Gregory RI. MicroRNA regulation of stem cell fate. Cell Stem Cell. 2: 195-6. PMID 18371442 DOI: 10.1016/J.Stem.2008.02.008  0.396
2008 Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of microRNA processing by Lin28. Science (New York, N.Y.). 320: 97-100. PMID 18292307 DOI: 10.1126/Science.1154040  0.509
2007 Chendrimada TP, Finn KJ, Ji X, Baillat D, Gregory RI, Liebhaber SA, Pasquinelli AE, Shiekhattar R. MicroRNA silencing through RISC recruitment of eIF6. Nature. 447: 823-8. PMID 17507929 DOI: 10.1038/Nature05841  0.512
2006 Gregory RI, Chendrimada TP, Shiekhattar R. MicroRNA biogenesis: isolation and characterization of the microprocessor complex. Methods in Molecular Biology (Clifton, N.J.). 342: 33-47. PMID 16957365 DOI: 10.1385/1-59745-123-1:33  0.492
2005 Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell. 123: 631-40. PMID 16271387 DOI: 10.1016/J.Cell.2005.10.022  0.474
2005 Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature. 436: 740-4. PMID 15973356 DOI: 10.1038/Nature03868  0.505
2005 Gregory RI, Shiekhattar R. MicroRNA biogenesis and cancer. Cancer Research. 65: 3509-12. PMID 15867338 DOI: 10.1158/0008-5472.Can-05-0298  0.514
2004 Gregory RI, Shiekhattar R. Chromatin modifiers and carcinogenesis. Trends in Cell Biology. 14: 695-702. PMID 15564046 DOI: 10.1016/J.Tcb.2004.10.002  0.319
2004 Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R. The Microprocessor complex mediates the genesis of microRNAs. Nature. 432: 235-40. PMID 15531877 DOI: 10.1038/Nature03120  0.519
2002 Gregory RI, O'Neill LP, Randall TE, Fournier C, Khosla S, Turner BM, Feil R. Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells. The Journal of Biological Chemistry. 277: 11728-34. PMID 11821379 DOI: 10.1074/Jbc.M105775200  0.325
Low-probability matches (unlikely to be authored by this person)
2016 Triboulet R, Pirouz M, Gregory RI. Abstract A41: A single let-7 microRNA bypasses LIN28-mediated repression Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-A41  0.292
1999 Gregory RI, Feil R. Analysis of chromatin in limited numbers of cells: a PCR-SSCP based assay of allele-specific nuclease sensitivity Nucleic Acids Research. 27: i-e32. DOI: 10.1093/Nar/27.22.E32-I  0.288
2001 Gregory RI, Randall TE, Johnson CA, Khosla S, Hatada I, O'Neill LP, Turner BM, Feil R. DNA methylation is linked to deacetylation of histone H3, but not H4, on the imprinted genes Snrpn and U2af1-rs1. Molecular and Cellular Biology. 21: 5426-36. PMID 11463825 DOI: 10.1128/Mcb.21.16.5426-5436.2001  0.286
2001 Thompson SL, Konfortova G, Gregory RI, Reik W, Dean W, Feil R. Environmental effects on genomic imprinting in mammals. Toxicology Letters. 120: 143-50. PMID 11323171 DOI: 10.1016/S0378-4274(01)00292-2  0.285
2021 Missios P, da Rocha EL, Pearson DS, Philipp J, Aleman MM, Pirouz M, Farache D, Franses JW, Kubaczka C, Tsanov KM, Jha DK, Pepe-Mooney B, Powers JT, Gregory RI, Lee AS, et al. LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy. The Journal of Clinical Investigation. 131. PMID 34779407 DOI: 10.1172/JCI145142  0.284
1999 Khosla S, Aitchison A, Gregory R, Allen ND, Feil R. Parental allele-specific chromatin configuration in a boundary-imprinting-control element upstream of the mouse H19 gene. Molecular and Cellular Biology. 19: 2556-66. PMID 10082521 DOI: 10.1128/Mcb.19.4.2556  0.28
2002 Matarazzo MR, De Bonis ML, Gregory RI, Vacca M, Hansen RS, Mercadante G, D'Urso M, Feil R, D'Esposito M. Allelic inactivation of the pseudoautosomal gene SYBL1 is controlled by epigenetic mechanisms common to the X and Y chromosomes. Human Molecular Genetics. 11: 3191-8. PMID 12444103 DOI: 10.1093/Hmg/11.25.3191  0.28
2021 Liu Q, Lang X, Gregory RI. An Informatics Pipeline for Profiling and Annotating RNA Modifications. Methods in Molecular Biology (Clifton, N.J.). 2298: 15-27. PMID 34085236 DOI: 10.1007/978-1-0716-1374-0_2  0.272
2013 Shinoda G, Shyh-Chang N, Soysa TY, Zhu H, Seligson MT, Shah SP, Abo-Sido N, Yabuuchi A, Hagan JP, Gregory RI, Asara JM, Cantley LC, Moss EG, Daley GQ. Fetal deficiency of lin28 programs life-long aberrations in growth and glucose metabolism. Stem Cells (Dayton, Ohio). 31: 1563-73. PMID 23666760 DOI: 10.1002/Stem.1423  0.272
2021 Orellana EA, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, Lim J, Aspris D, Sendinc E, Garyfallos DA, Gu M, Ali R, Gutierrez A, Mikutis S, Bernardes GJL, ... ... Gregory RI, et al. METTL1-mediated mG modification of Arg-TCT tRNA drives oncogenic transformation. Molecular Cell. PMID 34352207 DOI: 10.1016/j.molcel.2021.06.031  0.269
2020 Cui J, Liu Q, Sendinc E, Shi Y, Gregory RI. Nucleotide resolution profiling of m3C RNA modification by HAC-seq. Nucleic Acids Research. PMID 33313824 DOI: 10.1093/nar/gkaa1186  0.268
2019 Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Stevenson KE, Neuberg DS, Orellana E, Stanulla M, Gregory RI, Bauer DE, Wagner FF, Stegmaier K, et al. Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias. Cancer Cell. 35: 664-676.e7. PMID 30991026 DOI: 10.1016/J.Ccell.2019.03.004  0.261
2022 Liu Q, Peng X, Shen M, Qian Q, Xing J, Li C, Gregory RI. Ribo-uORF: a comprehensive data resource of upstream open reading frames (uORFs) based on ribosome profiling. Nucleic Acids Research. PMID 36440758 DOI: 10.1093/nar/gkac1094  0.243
2023 Li J, Wang L, Hahn Q, Nowak RP, Viennet T, Orellana EA, Roy Burman SS, Yue H, Hunkeler M, Fontana P, Wu H, Arthanari H, Fischer ES, Gregory RI. Structural basis of regulated mG tRNA modification by METTL1-WDR4. Nature. 613: 391-397. PMID 36599985 DOI: 10.1038/s41586-022-05566-4  0.235
2021 Ramírez-Moya J, Miliotis C, Baker AR, Gregory RI, Slack FJ, Santisteban P. An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks. Molecular Cancer. 20: 115. PMID 34496885 DOI: 10.1186/s12943-021-01401-y  0.232
2021 Mapperley C, van de Lagemaat LN, Lawson H, Tavosanis A, Paris J, Campos J, Wotherspoon D, Durko J, Sarapuu A, Choe J, Ivanova I, Krause DS, von Kriegsheim A, Much C, Morgan M, ... Gregory RI, et al. The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function. The Journal of Experimental Medicine. 218. PMID 33156926 DOI: 10.1084/jem.20200829  0.232
2020 Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, Raiser DM, Siva K, Basak A, Pirouz M, Shah AN, McGrath K, Humphries JM, Stillman E, Alter BP, ... ... Gregory RI, et al. Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia. Science Translational Medicine. 12. PMID 33087503 DOI: 10.1126/scitranslmed.abb5831  0.215
2015 Fong CY, Gilan O, Lam EY, Rubin AF, Ftouni S, Tyler D, Stanley K, Sinha D, Yeh P, Morison J, Giotopoulos G, Lugo D, Jeffrey P, Lee SC, Carpenter C, ... Gregory R, et al. BET inhibitor resistance emerges from leukaemia stem cells. Nature. 525: 538-42. PMID 26367796 DOI: 10.1038/Nature14888  0.213
2017 Tyler DS, Vappiani J, Cañeque T, Lam EYN, Ward A, Gilan O, Chan YC, Hienzsch A, Rutkowska A, Werner T, Wagner AJ, Lugo D, Gregory R, Ramirez Molina C, Garton N, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science (New York, N.Y.). PMID 28619718 DOI: 10.1126/science.aal2066  0.21
2017 Qiu Q, Wu R, Lanieri L, Maloney E, Skaletskaya A, Jin S, Wang L, Ab O, Ponte J, Setiady Y, Widdison W, Keating T, Chari R, Gregory R, Hong E. Abstract 71: Bystander activity andin vivoefficacy of a folate receptor α (FRα)-targeting antibody-drug conjugate with a novel peptide linker Cancer Research. 77: 71-71. DOI: 10.1158/1538-7445.Am2017-71  0.203
2021 Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, et al. SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Science Immunology. 6. PMID 33827897 DOI: 10.1126/sciimmunol.abg0833  0.196
2022 Yang X, Triboulet R, Liu Q, Sendinc E, Gregory RI. Exon junction complex shapes the mA epitranscriptome. Nature Communications. 13: 7904. PMID 36550132 DOI: 10.1038/s41467-022-35643-1  0.182
2019 Deats W, Widdison W, Costoplus J, Matin B, McBrine N, Bartle L, Ab O, Gregory R, Pinkas J. Abstract 3898: Preclinical evaluation of DM21, a next-generation maytansinoid payload with a stable peptide linker Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3898  0.179
2018 Dobenecker MW, Park JS, Marcello J, McCabe MT, Gregory R, Knight SD, Rioja I, Bassil AK, Prinjha RK, Tarakhovsky A. Signaling function of PRC2 is essential for TCR-driven T cell responses. The Journal of Experimental Medicine. PMID 29523590 DOI: 10.1084/jem.20170084  0.179
2003 Lanciotti J, Song A, Doukas J, Sosnowski B, Pierce G, Gregory R, Wadsworth S, O'Riordan C. Targeting adenoviral vectors using heterofunctional polyethylene glycol FGF2 conjugates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 99-107. PMID 12842433 DOI: 10.1016/S1525-0016(03)00139-4  0.177
2021 Xiong X, Hou L, Park YP, Molinie B, Gregory RI, Kellis M. Genetic drivers of mA methylation in human brain, lung, heart and muscle. Nature Genetics. PMID 34211177 DOI: 10.1038/s41588-021-00890-3  0.164
2013 Christin PA, Boxall SF, Gregory R, Edwards EJ, Hartwell J, Osborne CP. Parallel recruitment of multiple genes into c4 photosynthesis. Genome Biology and Evolution. 5: 2174-87. PMID 24179135 DOI: 10.1093/Gbe/Evt168  0.155
2018 AlQallaf H, Hamada Y, Blanchard S, Shin D, Gregory R, Srinivasan M. Differential profiles of soluble and cellular toll like receptor (TLR)-2 and 4 in chronic periodontitis. Plos One. 13: e0200231. PMID 30571680 DOI: 10.1371/Journal.Pone.0200231  0.153
2021 Elfiky AMI, Ghiboub M, Li Yim AYF, Hageman IL, Verhoeff J, de Krijger M, van Hamersveld PHP, Welting O, Admiraal I, Rahman S, Garcia-Vallejo JJ, Wildenberg ME, Tomlinson L, Gregory R, Rioja I, et al. Carboxylesterase-1 assisted targeting of HDAC inhibitors to mononuclear myeloid cells in Inflammatory Bowel Disease. Journal of Crohn's & Colitis. PMID 34633041 DOI: 10.1093/ecco-jcc/jjab176  0.148
2014 Wilson R, Bourne C, Chaudhuri RR, Gregory R, Kenny J, Cossins A. Single-step selection of bivalent aptamers validated by comparison with SELEX using high-throughput sequencing. Plos One. 9: e100572. PMID 24963654 DOI: 10.1371/journal.pone.0100572  0.144
2022 Humphreys PG, Anderson NA, Bamborough P, Baxter A, Chung CW, Cookson R, Craggs PD, Dalton T, Fournier JCL, Gordon LJ, Gray HF, Gray MW, Gregory R, Hirst DJ, Jamieson C, et al. Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432. Journal of Medicinal Chemistry. PMID 36378954 DOI: 10.1021/acs.jmedchem.2c01102  0.125
2020 Greco R, Qu H, Qu H, Theilhaber J, Shapiro G, Gregory R, Winter C, Malkova N, Sun F, Jaworski J, Best A, Pao L, Hebert A, Levit M, Protopopov A, et al. Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade. Oncoimmunology. 9: 1811605. PMID 33224628 DOI: 10.1080/2162402X.2020.1811605  0.122
2016 D'Amore R, Ijaz UZ, Schirmer M, Kenny JG, Gregory R, Darby AC, Shakya M, Podar M, Quince C, Hall N. A comprehensive benchmarking study of protocols and sequencing platforms for 16S rRNA community profiling. Bmc Genomics. 17: 55. PMID 26763898 DOI: 10.1186/S12864-015-2194-9  0.108
2012 Christin PA, Edwards EJ, Besnard G, Boxall SF, Gregory R, Kellogg EA, Hartwell J, Osborne CP. Adaptive evolution of C(4) photosynthesis through recurrent lateral gene transfer. Current Biology : Cb. 22: 445-9. PMID 22342748 DOI: 10.1016/J.Cub.2012.01.054  0.102
2021 Li J, Gregory RI. Mining for METTL3 inhibitors to suppress cancer. Nature Structural & Molecular Biology. PMID 34040230 DOI: 10.1038/s41594-021-00606-5  0.101
2020 Ponte JF, Lanieri L, Khera E, Laleau R, Ab O, Espelin C, Kohli N, Matin B, Setiady Y, Miller ML, Keating TA, Chari R, Pinkas J, Gregory R, Thurber GM. Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody Drug Conjugates to Increase In Vivo Efficacy. Molecular Cancer Therapeutics. PMID 33177153 DOI: 10.1158/1535-7163.MCT-20-0451  0.096
2003 Gregory R. Functional seeing. Perception. 32: 1155-7. PMID 14700250 DOI: 10.1068/p3210ed  0.086
2011 Gregory R, Darby AC, Irving H, Coulibaly MB, Hughes M, Koekemoer LL, Coetzee M, Ranson H, Hemingway J, Hall N, Wondji CS. A de novo expression profiling of Anopheles funestus, malaria vector in Africa, using 454 pyrosequencing. Plos One. 6: e17418. PMID 21364769 DOI: 10.1371/Journal.Pone.0017418  0.077
2019 Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Orellana E, Gregory R, Bauer D, Wagner F, Stegmaier K, Stanulla M, Gutierrez A. GENOME-WIDE CRISPR-CAS9 SCREEN REVEALS SYNTHETIC LETHALITY OF WNT PATHWAY ACTIVATION AND ASPARAGINASE IN DRUG-RESISTANT ACUTE LEUKEMIAS Hemasphere. 3: 384. DOI: 10.1097/01.hs9.0000561716.06360.25  0.073
2023 Brunner FS, Payne A, Cairns E, Airey G, Gregory R, Pickwell ND, Wilson M, Carlile M, Holmes N, Hill V, Child H, Tomlinson J, Ahmed S, Denise H, Rowe W, et al. Utility of wastewater genomic surveillance compared to clinical surveillance to track the spread of the SARS-CoV-2 Omicron variant across England. Water Research. 247: 120804. PMID 37925861 DOI: 10.1016/j.watres.2023.120804  0.058
2021 Ball AL, Bloch KM, Rainbow L, Liu X, Kenny J, Lyon JJ, Gregory R, Alfirevic A, Chadwick AE. Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers. Archives of Toxicology. PMID 33585966 DOI: 10.1007/s00204-021-02988-3  0.056
2019 Floyd JS, Bloch KM, Brody JA, Maroteau C, Siddiqui MK, Gregory R, Carr DF, Molokhia M, Liu X, Bis JC, Ahmed A, Liu X, Hallberg P, Yue QY, Magnusson PKE, et al. Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing. Plos One. 14: e0218115. PMID 31242253 DOI: 10.1371/Journal.Pone.0218115  0.055
2018 Hicks N, Liu X, Gregory R, Kenny J, Lucaci A, Lenzi L, Paterson DM, Duncan KR. Temperature Driven Changes in Benthic Bacterial Diversity Influences Biogeochemical Cycling in Coastal Sediments. Frontiers in Microbiology. 9: 1730. PMID 30190707 DOI: 10.3389/fmicb.2018.01730  0.053
2022 Weston DJ, Dave M, Colizza K, Thomas S, Tomlinson L, Gregory R, Beaumont C, Pirhalla J, Dear GJ. A discovery biotransformation strategy: combining tools with high-resolution mass spectrometry and software-assisted data analysis for high-throughput metabolism. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-15. PMID 36227740 DOI: 10.1080/00498254.2022.2136042  0.051
2010 Weng Y, Guo X, Gregory R, Xie D. A novel antibacterial dental glass-ionomer cement. European Journal of Oral Sciences. 118: 531-4. PMID 20853548 DOI: 10.1111/J.1600-0722.2010.00770.X  0.05
2008 Mensch BS, Hewett PC, Gregory R, Helleringer S. Sexual behavior and STI/HIV status among adolescents in rural Malawi: an evaluation of the effect of interview mode on reporting. Studies in Family Planning. 39: 321-34. PMID 19248718 DOI: 10.1111/J.1728-4465.2008.00178.X  0.039
2009 Anstis S, Gregory R, Heard P. The triangle-bisection illusion. Perception. 38: 321-32. PMID 19485129 DOI: 10.1068/P5866  0.035
2012 Gregory R. Governance. Opening up to close scrutiny. The Health Service Journal. 122: 25. PMID 23323480  0.033
2015 Inger R, Gregory R, Duffy JP, Stott I, Voříšek P, Gaston KJ. Common European birds are declining rapidly while less abundant species' numbers are rising. Ecology Letters. 18: 28-36. PMID 25363472 DOI: 10.1111/ele.12387  0.032
2023 Rigal S, Dakos V, Alonso H, Auniņš A, Benkő Z, Brotons L, Chodkiewicz T, Chylarecki P, de Carli E, Del Moral JC, Domşa C, Escandell V, Fontaine B, Foppen R, Gregory R, et al. Farmland practices are driving bird population decline across Europe. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216573120. PMID 37186854 DOI: 10.1073/pnas.2216573120  0.03
2008 Biddlecom A, Gregory R, Lloyd CB, Mensch BS. Associations between premarital sex and leaving school in four sub-Saharan African countries. Studies in Family Planning. 39: 337-50. PMID 19248719 DOI: 10.1111/J.1728-4465.2008.00179.X  0.021
2004 Gregory R. The blind leading the sighted. Nature. 430: 836. PMID 15318199 DOI: 10.1038/430836a  0.021
2010 Sherling M, Friedman PM, Adrian R, Burns AJ, Conn H, Fitzpatrick R, Gregory R, Kilmer S, Lask G, Narurkar V, Katz TM, Avram M. Consensus recommendations on the use of an erbium-doped 1,550-nm fractionated laser and its applications in dermatologic laser surgery. Dermatologic Surgery : Official Publication For American Society For Dermatologic Surgery [Et Al.]. 36: 461-9. PMID 20187898 DOI: 10.1111/j.1524-4725.2010.01483.x  0.015
2003 Gregory R. Significance Perception. 32: 127-130. PMID 12696660 DOI: 10.1068/p3202ed  0.012
2004 Gregory R. Sciart frame up. Perception. 33: 257-8. PMID 15176611 DOI: 10.1068/p3303ed  0.011
2019 Tayler E, Gregory R, Bloom G, Salama P, Balkhy H. Universal health coverage: an opportunity to address antimicrobial resistance? The Lancet. Global Health. PMID 31548131 DOI: 10.1016/S2214-109X(19)30362-6  0.01
2014 Gregory R. Seeing oneself. Perception. 42: 1279-80. PMID 24601039 DOI: 10.1068/p3008edn  0.01
2009 Gregory R, Heard P. Trumping eyes. Part 2. Perception. 38: 1265-6. PMID 19911624 DOI: 10.1068/P3809Ed  0.01
2009 Gregory R, Heard P. Trumping eyes. Part 1. Perception. 38: 1107-8. PMID 19817144 DOI: 10.1068/P3808Ed  0.01
2004 Paton R, Gregory R, Vlachos C, Saunders J, Wu H. Evolvable social agents for bacterial systems modeling. Ieee Transactions On Nanobioscience. 3: 208-16. PMID 15473073  0.01
2004 Gregory R. Curious asymmetries. Part 2. Perception. 33: 765-8. PMID 15460505 DOI: 10.1068/p3307ed  0.01
2004 Gregory R. Curious asymmetries. Part 1. Perception. 33: 639-42. PMID 15330361 DOI: 10.1068/p3306ed  0.01
2003 Gregory R. Animal consciousness. Perception. 32: 1411-3. PMID 14992419 DOI: 10.1068/p3212ed  0.01
2003 Gregory R. War with Scotland? Perception. 32: 899-902. PMID 14580137 DOI: 10.1068/p3208ed  0.01
2003 Gregory R. Seeing--by art and science. Perception. 32: 643-4. PMID 12892425 DOI: 10.1068/p3206ed  0.01
2003 Gregory R, Heard P. Pulfrich on wheels Perception. 32: 253-254. PMID 12696669 DOI: 10.1068/P3202Pp  0.01
2002 Gregory R. Tunnel vision to tunnel mind Perception. 31: 773-774. PMID 12206525 DOI: 10.1068/p3107ed  0.01
2002 Gregory R. Stars to eyes by adaptive optics Perception. 31: 1-3. PMID 11922116 DOI: 10.1068/p3101ed  0.01
2001 Gregory R. Seeing oneself. Perception. 30: 903-4. PMID 11578076 DOI: 10.1068/p3008ed  0.01
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