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Lejla Zubcevic, DPhil - Publications

Affiliations: 
2008-2012 Physics University of Oxford, Oxford, United Kingdom 
 2013-2019 Biochemistry Duke University, Durham, NC 
 2020- Biochemistry and Molecular Biology University of Kansas Medical Center, Kansas City, KS, United States 
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Karuppan S, Schrag LG, Pastrano CM, Jara-Oseguera A, Zubcevic L. Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel. Proceedings of the National Academy of Sciences of the United States of America. 121: e2403333121. PMID 38923985 DOI: 10.1073/pnas.2403333121  0.529
2021 Zubcevic L. Preparation of the Transient Receptor Potential Vanilloid 2 (TRPV2) channel for structural studies. Methods in Enzymology. 653: 21-48. PMID 34099173 DOI: 10.1016/bs.mie.2020.12.002  0.451
2020 Zubcevic L. Temperature-sensitive transient receptor potential vanilloid channels: structural insights into ligand-dependent activation. British Journal of Pharmacology. PMID 33155670 DOI: 10.1111/bph.15310  0.414
2020 Zubcevic L. TRP Channels, Conformational Flexibility, and the Lipid Membrane. The Journal of Membrane Biology. 253: 299-308. PMID 32601711 DOI: 10.1007/s00232-020-00127-0  0.397
2020 Csanády L, Du J, Zubcevic L. Decision letter: Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms Elife. DOI: 10.7554/Elife.58660.Sa1  0.432
2019 Suo Y, Wang Z, Zubcevic L, Hsu AL, He Q, Borgnia MJ, Ji RR, Lee SY. Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel. Neuron. PMID 31866091 DOI: 10.2210/Pdb6Pqp/Pdb  0.637
2019 Zubcevic L, Lee SY. The role of π-helices in TRP channel gating. Current Opinion in Structural Biology. PMID 31378426 DOI: 10.1016/J.Sbi.2019.06.011  0.687
2019 Zubcevic L, Hsu AL, Borgnia MJ, Lee SY. Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes. Elife. 8. PMID 31090543 DOI: 10.7554/Elife.45779  0.674
2019 Zubcevic L, Borschel WF, Hsu AL, Borgnia MJ, Lee SY. Regulatory switch at the cytoplasmic interface controls TRPV channel gating. Elife. 8. PMID 31070581 DOI: 10.2210/Pdb6Ot2/Pdb  0.647
2019 Zubcevic L, Borschel WF, Hsu AL, Borgnia MJ, Lee S. Author response: Regulatory switch at the cytoplasmic interface controls TRPV channel gating Elife. DOI: 10.7554/Elife.47746.038  0.61
2019 Zubcevic L, Hsu AL, Borgnia MJ, Lee S. Author response: Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes Elife. DOI: 10.7554/Elife.45779.047  0.578
2018 Zubcevic L, Herzik MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY. Conformational ensemble of the human TRPV3 ion channel. Nature Communications. 9: 4773. PMID 30429472 DOI: 10.1038/s41467-018-07117-w  0.637
2018 Zubcevic L, Le S, Yang H, Lee SY. Conformational plasticity in the selectivity filter of the TRPV2 ion channel. Nature Structural & Molecular Biology. 25: 405-415. PMID 29728656 DOI: 10.2210/Pdb6Bwj/Pdb  0.598
2017 Yin Y, Wu M, Zubcevic L, Borschel WF, Lander GC, Lee SY. Structure of the cold- and menthol-sensing ion channel TRPM8. Science (New York, N.Y.). PMID 29217583 DOI: 10.1126/Science.Aan4325  0.602
2016 Zubcevic L, Herzik MA, Chung BC, Liu Z, Lander GC, Lee SY. Cryo-electron microscopy structure of the TRPV2 ion channel. Nature Structural & Molecular Biology. PMID 26779611 DOI: 10.1038/Nsmb.3159  0.643
2016 Zubcevic L, Herzik M, Chung BC, Lander GC, Lee SY. Cryo-Electron Microscopy of the Trpv2 Ion Channel Nature Structural & Molecular Biology. 23: 180. DOI: 10.2210/Pdb5An8/Pdb  0.488
2015 Zubcevic L, Wang S, Bavro VN, Lee SJ, Nichols CG, Tucker SJ. Modular Design of the Selectivity Filter Pore Loop in a Novel Family of Prokaryotic 'Inward Rectifier' (NirBac) channels. Scientific Reports. 5: 15305. PMID 26470642 DOI: 10.1038/Srep15305  0.677
2014 Zubcevic L, Bavro VN, Muniz JR, Schmidt MR, Wang S, De Zorzi R, Venien-Bryan C, Sansom MS, Nichols CG, Tucker SJ. Control of KirBac3.1 potassium channel gating at the interface between cytoplasmic domains. The Journal of Biological Chemistry. 289: 143-51. PMID 24257749 DOI: 10.1074/Jbc.M113.501833  0.685
2012 Bavro VN, De Zorzi R, Schmidt MR, Muniz JR, Zubcevic L, Sansom MS, Vénien-Bryan C, Tucker SJ. Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating. Nature Structural & Molecular Biology. 19: 158-63. PMID 22231399 DOI: 10.1038/Nsmb.2208  0.672
2012 Bavro VN, De Zorzi R, Schmidt MR, Muniz JR, Zubcevic L, Sansom MS, Venien-Bryan C, Tucker SJ. Crystal Structure of a Prokaryotic Kir Channel in an Open Conformation Biophysical Journal. 102: 536a. DOI: 10.1016/J.Bpj.2011.11.2928  0.658
2009 Shimomura K, Flanagan SE, Zadek B, Lethby M, Zubcevic L, Girard CA, Petz O, Mannikko R, Kapoor RR, Hussain K, Skae M, Clayton P, Hattersley A, Ellard S, Ashcroft FM. Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism. Embo Molecular Medicine. 1: 166-77. PMID 20049716 DOI: 10.1002/Emmm.200900018  0.627
2009 Ashcroft FM, Zubcevic L. Retraction for Ma et al. "Glucose regulates the effects of leptin on hypothalamic POMC neurons". Proceedings of the National Academy of Sciences of the United States of America. 106: 7263. PMID 19380749 DOI: 10.1073/Pnas.0902342106  0.379
2009 Girard CA, Wunderlich FT, Shimomura K, Collins S, Kaizik S, Proks P, Abdulkader F, Clark A, Ball V, Zubcevic L, Bentley L, Clark R, Church C, Hugill A, Galvanovskis J, et al. Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes. The Journal of Clinical Investigation. 119: 80-90. PMID 19065048 DOI: 10.1172/Jci35772  0.498
2008 Ma X, Zubcevic L, Ashcroft FM. Glucose regulates the effects of leptin on hypothalamic POMC neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 9811-6. PMID 18599453 DOI: 10.1073/Pnas.0800952105  0.389
2008 Staník J, Lethby M, Flanagan SE, Gasperíková D, Milosovicová B, Lever M, Bullman H, Zubcevic L, Hattersley AT, Ellard S, Ashcroft FM, Klimes I. Coincidence of a novel KCNJ11 missense variant R365H with a paternally inherited 6q24 duplication in a patient with transient neonatal diabetes. Diabetes Care. 31: 1736-7. PMID 18556340 DOI: 10.2337/Dc08-0549  0.406
2007 Mlynarski W, Tarasov AI, Gach A, Girard CA, Pietrzak I, Zubcevic L, Kusmierek J, Klupa T, Malecki MT, Ashcroft FM. Sulfonylurea improves CNS function in a case of intermediate DEND syndrome caused by a mutation in KCNJ11. Nature Clinical Practice. Neurology. 3: 640-5. PMID 17982434 DOI: 10.1038/Ncpneuro0640  0.548
2007 Ma X, Zubcevic L, Brüning JC, Ashcroft FM, Burdakov D. Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1529-33. PMID 17301161 DOI: 10.1523/Jneurosci.3583-06.2007  0.375
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