| Year |
Citation |
Score |
| 2024 |
Sammons RM, Devkota AK, Kaoud TS, Warthaka M, Cho EJ, Dalby KN. Steady State and Time-Dependent Fluorescent Peptide Assays for Protein Kinases. Current Protocols. 4: e998. PMID 38439594 DOI: 10.1002/cpz1.998 |
0.648 |
|
| 2023 |
Postiglione AE, Adams LL, Ekhator ES, Odelade AE, Patwardhan S, Chaudhari M, Pardue AS, Kumari A, LeFever WA, Tornow OP, Kaoud TS, Neiswinger J, Jeong JS, Parsonage D, Nelson KJ, et al. Hydrogen peroxide-dependent oxidation of ERK2 within its D-recruitment site alters its substrate selection. Iscience. 26: 107817. PMID 37744034 DOI: 10.1016/j.isci.2023.107817 |
0.624 |
|
| 2023 |
Zhan X, Kaoud TS, Dalby KN, Gurevich EV, Gurevich VV. Arrestin-3-Dependent Activation of c-Jun N-Terminal Kinases (JNKs). Current Protocols. 3: e839. PMID 37668419 DOI: 10.1002/cpz1.839 |
0.641 |
|
| 2023 |
Silva RP, Huang Y, Nguyen AW, Hsieh CL, Olaluwoye OS, Kaoud TS, Wilen RE, Qerqez AN, Park JG, Khalil AM, Azouz LR, Le KC, Bohanon AL, DiVenere AM, Liu Y, et al. Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses. Elife. 12. PMID 36942851 DOI: 10.7554/eLife.83710 |
0.772 |
|
| 2022 |
Sammons RM, Bohanon AL, Kowtha A, Dejong A, Cho EJ, Kaoud TS, Dalby KN. High-Throughput Assay for Identifying Diverse Antagonists of the Binding Interaction between the ACE2 Receptor and the Dynamic Spike Proteins of SARS-CoV-2. Acs Infectious Diseases. 8: 2259-2270. PMID 36315931 DOI: 10.1021/acsinfecdis.2c00297 |
0.783 |
|
| 2022 |
Soleimani M, Somma A, Kaoud TS, Goyal R, Bustamante J, Wylie DC, Holay N, Looney AP, Giri U, Triplett T, Dalby KN, Kowalski J, Eckhardt SG, Van Den Berg C. Covalent JNK inhibitor, JNK-IN-8, suppresses tumor growth in triple-negative breast cancer by activating TFEB and TFE3 mediated lysosome biogenesis and autophagy. Molecular Cancer Therapeutics. PMID 35977156 DOI: 10.1158/1535-7163.MCT-21-1044 |
0.641 |
|
| 2022 |
Perry-Hauser NA, Kaoud TS, Stoy H, Zhan X, Chen Q, Dalby KN, Iverson TM, Gurevich VV, Gurevich EV. Short Arrestin-3-Derived Peptides Activate JNK3 in Cells. International Journal of Molecular Sciences. 23. PMID 35955810 DOI: 10.3390/ijms23158679 |
0.63 |
|
| 2022 |
Paul A, Kumar S, Kaoud TS, Pickett MR, Bohanon AL, Zoldan J, Dalby KN, Parekh SH. Biomechanical Dependence of SARS-CoV-2 Infections. Acs Applied Bio Materials. PMID 35486915 DOI: 10.1021/acsabm.2c00143 |
0.753 |
|
| 2022 |
Zeng L, Kaoud TS, Zamora-Olivares D, Bohanon AL, Li Y, Pridgen JR, Ekpo YE, Zhuang DL, Nye JR, Telles M, Winkler M, Rivera S, Marini F, Dalby KN, Anslyn EV. Multiplexing the Quantitation of MAP Kinase Activities Using Differential Sensing. Journal of the American Chemical Society. 144: 4017-4025. PMID 35195411 DOI: 10.1021/jacs.1c12757 |
0.827 |
|
| 2021 |
Javanmardi K, Chou CW, Terrace CI, Annapareddy A, Kaoud TS, Guo Q, Lutgens J, Zorkic H, Horton AP, Gardner EC, Nguyen G, Boutz DR, Goike J, Voss WN, Kuo HC, et al. Rapid characterization of spike variants via mammalian cell surface display. Molecular Cell. 81: 5099-5111.e8. PMID 34919820 DOI: 10.1016/j.molcel.2021.11.024 |
0.483 |
|
| 2021 |
Ramadan M, A M M Elshaier Y, Aly AA, Abdel-Aziz M, Fathy HM, Brown AB, Pridgen JR, Dalby KN, Kaoud TS. Development of 2'-aminospiro [pyrano[3,2-c]quinoline]-3'-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation. Bioorganic Chemistry. 116: 105344. PMID 34598088 DOI: 10.1016/j.bioorg.2021.105344 |
0.675 |
|
| 2020 |
Zamora-Olivares D, Pridgen JR, Zeng L, Kaoud TS, Anslyn EV, Dalby KN. Abstract 6312: Use of differential sensing-based biosensors to quantify ERK kinase activity in complex biological samples Cancer Research. 80: 6312-6312. DOI: 10.1158/1538-7445.Am2020-6312 |
0.374 |
|
| 2019 |
Kaoud TS, Mohassab AM, Hassan HA, Yan C, Van Ravenstein SX, Abdelhamid D, Dalby KN, Abdel-Aziz M. NO-releasing STAT3 inhibitors suppress BRAF-mutant melanoma growth. European Journal of Medicinal Chemistry. 111885. PMID 31784187 DOI: 10.1016/j.ejmech.2019.111885 |
0.597 |
|
| 2019 |
Zamora-Olivares D, Kaoud TS, Zeng L, Pridgen JR, Zhuang DL, Ekpo YE, Nye JR, Telles M, Anslyn EV, Dalby KN. Quantification of ERK kinase activity in biological samples using differential sensing. Acs Chemical Biology. PMID 31775004 DOI: 10.1021/Acschembio.9B00580 |
0.64 |
|
| 2019 |
Kaoud TS, Johnson WH, Ebelt ND, Piserchio A, Zamora-Olivares D, Van Ravenstein SX, Pridgen JR, Edupuganti R, Sammons R, Cano M, Warthaka M, Harger M, Tavares CDJ, Park J, Radwan MF, et al. Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo. Nature Communications. 10: 5232. PMID 31745079 DOI: 10.1038/S41467-019-12996-8 |
0.809 |
|
| 2019 |
Perry NA, Fialkowski KP, Kaoud TS, Kaya AI, Chen AL, Taliaferro JM, Gurevich VV, Dalby KN, Iverson TM. Arrestin-3 interaction with maternal embryonic leucine-zipper kinase. Cellular Signalling. 109366. PMID 31352007 DOI: 10.1016/J.Cellsig.2019.109366 |
0.803 |
|
| 2019 |
Du L, Anderson A, Nguyen K, Ojeda SS, Ortiz-Rivera I, Nguyen TN, Zhang T, Kaoud TS, Gray NS, Dalby KN, Tsai KY. JNK2 is required for tumorigenic properties of melanoma cells. Acs Chemical Biology. PMID 31063355 DOI: 10.1021/acschembio.9b00083 |
0.624 |
|
| 2019 |
Sammons RM, Perry NA, Li Y, Cho EJ, Piserchio A, Zamora-Olivares DP, Ghose R, Kaoud TS, Debevec G, Bartholomeusz C, Gurevich VV, Iverson TM, Giulianotti M, Houghten RA, Dalby KN. A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation. Acs Chemical Biology. PMID 31058487 DOI: 10.1021/Acschembio.9B00093 |
0.84 |
|
| 2019 |
Hassan AA, Aly AA, Mohamed NK, El Shaieb KM, Makhlouf MM, Abdelhafez EMN, Bräse S, Nieger M, Dalby KN, Kaoud TS. Design, synthesis, and DNA interaction studies of furo-imidazo[3.3.3]propellane derivatives: Potential anticancer agents. Bioorganic Chemistry. 85: 585-599. PMID 30878891 DOI: 10.1016/J.Bioorg.2019.02.027 |
0.507 |
|
| 2019 |
Kaoud TS, Johnson WH, Ebelt ND, Piserchio A, Zamora-Olivares D, Ravenstein SV, Pridgen JR, Edupuganti R, Sammons R, Cano M, Warthaka M, Ren P, Anslyn EV, Tsai KY, Ghose R, et al. Abstract 3872: Targeting multi-functional ERK-protein complexesin vivo Cancer Research. 79: 3872-3872. DOI: 10.1158/1538-7445.Am2019-3872 |
0.835 |
|
| 2019 |
Zamora-Olivares D, Kaoud TS, Zeng L, Telles M, Anslyn EV, Dalby KN. Abstract 2172: Quantification of ERK activity in cancer cell lysates and tumor extract using differential sensing methods Cancer Research. 79: 2172-2172. DOI: 10.1158/1538-7445.Am2019-2172 |
0.373 |
|
| 2018 |
Perry NA, Kaoud TS, Ortega OO, Kaya AI, Marcus DJ, Pleinis JM, Berndt S, Chen Q, Zhan X, Dalby KN, Lopez CF, Iverson TM, Gurevich VV. Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification. Proceedings of the National Academy of Sciences of the United States of America. PMID 30591558 DOI: 10.1073/Pnas.1819230116 |
0.624 |
|
| 2018 |
Aly AA, El-Sheref EM, Bakheet MEM, Mourad MAE, Bräse S, Ibrahim MAA, Nieger M, Garvalov BK, Dalby KN, Kaoud TS. Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma. Bioorganic Chemistry. 82: 290-305. PMID 30396063 DOI: 10.1016/J.Bioorg.2018.10.044 |
0.638 |
|
| 2018 |
Guo HF, Tsai CL, Terajima M, Tan X, Banerjee P, Miller MD, Liu X, Yu J, Byemerwa J, Alvarado S, Kaoud TS, Dalby KN, Bota-Rabassedas N, Chen Y, Yamauchi M, et al. Author Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe-binding. Nature Communications. 9: 2719. PMID 29988035 DOI: 10.1038/S41467-018-05295-1 |
0.451 |
|
| 2018 |
Guo HF, Tsai CL, Terajima M, Tan X, Banerjee P, Miller MD, Liu X, Yu J, Byemerwa J, Alvarado S, Kaoud TS, Dalby KN, Bota-Rabassedas N, Chen Y, Yamauchi M, et al. Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding. Nature Communications. 9: 512. PMID 29410444 DOI: 10.1038/S41467-018-02859-Z |
0.528 |
|
| 2017 |
Ebelt ND, Kaoud TS, Edupuganti R, Van Ravenstein S, Dalby KN, Van Den Berg CL. A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib. Oncotarget. 8: 104894-104912. PMID 29285221 DOI: 10.18632/oncotarget.20581 |
0.601 |
|
| 2017 |
Jose J, Tavares CDJ, Ebelt ND, Lodi A, Edupuganti R, Xie X, Devkota AK, Kaoud TS, Van Den Berg CL, Anslyn EV, Tiziani S, Bartholomeusz C, Dalby KN. Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth. Acs Medicinal Chemistry Letters. 8: 1072-1076. PMID 29057053 DOI: 10.1021/Acsmedchemlett.7B00282 |
0.792 |
|
| 2017 |
Mohassab AM, Hassan HA, Abdelhamid D, Abdel-Aziz M, Dalby KN, Kaoud TS. Novel quinoline incorporating 1,2,4-triazole/oxime hybrids: Synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations. Bioorganic Chemistry. 75: 242-259. PMID 29032325 DOI: 10.1016/j.bioorg.2017.09.018 |
0.499 |
|
| 2017 |
Piserchio A, Warthaka M, Kaoud TS, Callaway K, Dalby KN, Ghose R. Local destabilization, rigid body, and fuzzy docking facilitate the phosphorylation of the transcription factor Ets-1 by the mitogen-activated protein kinase ERK2. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716922 DOI: 10.1073/Pnas.1702973114 |
0.825 |
|
| 2016 |
Tavares CD, Giles DH, Stancu G, Chitjian CA, Ferguson SB, Wellmann RM, Kaoud TS, Ghose R, Dalby KN. Signal Integration at Elongation Factor 2 Kinase; the Roles of Calcium, Calmodulin and Ser-500 Phosphorylation. The Journal of Biological Chemistry. PMID 27956550 DOI: 10.1074/Jbc.M116.753277 |
0.794 |
|
| 2016 |
Xie X, Kaoud TS, Edupuganti R, Zhang T, Kogawa T, Zhao Y, Chauhan GB, Giannoukos DN, Qi Y, Tripathy D, Wang J, Gray NS, Dalby KN, Bartholomeusz C, Ueno NT. c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun. Oncogene. PMID 27941886 DOI: 10.1038/onc.2016.417 |
0.59 |
|
| 2016 |
Zhan X, Stoy H, Kaoud TS, Perry NA, Chen Q, Perez A, Els-Heindl S, Slagis JV, Iverson TM, Beck-Sickinger AG, Gurevich EV, Dalby KN, Gurevich VV. Peptide mini-scaffold facilitates JNK3 activation in cells. Scientific Reports. 6: 21025. PMID 26868142 DOI: 10.1038/Srep21025 |
0.625 |
|
| 2016 |
Kaoud TS, Xie X, Park J, Tavares CDJ, Mitra S, Cano M, Radwan MF, Bartholomeusz C, Dalby KN. Abstract A17: TRPM7 kinase domain is involved in breast tumor cell metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-A17 |
0.818 |
|
| 2016 |
Ebelt ND, Taveres CDJ, Xie X, Naguib YW, Jose J, Ruwona TB, Devkota AK, Park J, Kaoud TS, Anslyn EV, Chang JT, Cui Z, Bartholomeusz C, Dalby KN. Abstract 3774: KD06 is a novel anti-cancer drug that causes cell death in triple-negative breast cancer cell lines and tumor xenografts Cancer Research. 76: 3774-3774. DOI: 10.1158/1538-7445.Am2016-3774 |
0.821 |
|
| 2016 |
Kaoud TS, Johnson WH, Ebelt ND, Piserchio A, Warthaka M, Cano M, Sammons R, Wang Q, Ren P, Ghose R, Dalby KN. Abstract 3771: Discovery of a covalent inhibitor of ERK docking-interactions that inhibits A375 melanoma cells proliferation Cancer Research. 76: 3771-3771. DOI: 10.1158/1538-7445.Am2016-3771 |
0.839 |
|
| 2015 |
Piserchio A, Ramakrishan V, Wang H, Kaoud TS, Arshava B, Dutta K, Dalby KN, Ghose R. Erratum: Structural and Dynamic Features of F-recruitment Site Driven Substrate Phosphorylation by ERK2. Scientific Reports. 5: 12369. PMID 26230360 DOI: 10.1038/srep12369 |
0.548 |
|
| 2015 |
Piserchio A, Ramakrishan V, Wang H, Kaoud TS, Arshava B, Dutta K, Dalby KN, Ghose R. Structural and Dynamic Features of F-recruitment Site Driven Substrate Phosphorylation by ERK2. Scientific Reports. 5: 11127. PMID 26054059 DOI: 10.1038/Srep11127 |
0.569 |
|
| 2015 |
Zhan X, Kook S, Kaoud TS, Dalby KN, Gurevich EV, Gurevich VV. Arrestin-3-Dependent Activation of c-Jun N-Terminal Kinases (JNKs). Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. 68: 2.12.1-2.12.26. PMID 25737158 DOI: 10.1002/0471141755.Ph0212S68 |
0.656 |
|
| 2015 |
Warthaka M, Adelmann CH, Kaoud TS, Edupuganti R, Yan C, Johnson WH, Ferguson S, Tavares CD, Pence LJ, Anslyn EV, Ren P, Tsai KY, Dalby KN. Quantification of a Pharmacodynamic ERK End Point in Melanoma Cell Lysates: Toward Personalized Precision Medicine. Acs Medicinal Chemistry Letters. 6: 47-52. PMID 25589929 DOI: 10.1021/Ml500198B |
0.802 |
|
| 2015 |
Sammons RM, Kaoud TS, Devkota AK, Cho EJ, Dalby KN. Abstract 3648: A high-throughput fluorescence anisotropy screening for discovery of inhibitors that target the D-recruitment site of ERK in vitro and in cells Cancer Research. 75: 3648-3648. DOI: 10.1158/1538-7445.Am2015-3648 |
0.85 |
|
| 2015 |
Kaoud TS, Xie X, Park J, Tavares CDJ, Mitra S, Cano M, Sammons RM, Radwan MF, Bartholomeusz C, Dalby KN. Abstract 3569: Inhibition of the TRPM7 kinase domain inhibits breast cancer cell migration and invasion and tumor metastasis Cancer Research. 75: 3569-3569. DOI: 10.1158/1538-7445.Am2015-3569 |
0.806 |
|
| 2015 |
Du L, Zhang T, Kaoud T, Gray N, Dalby K, Tsai KY. Abstract 1941: Distinct roles of c-Jun N-terminal kinase (JNK) isoforms in skin cancer Cancer Research. 75: 1941-1941. DOI: 10.1158/1538-7445.Am2015-1941 |
0.661 |
|
| 2014 |
Zamora-Olivares D, Kaoud TS, Jose J, Ellington A, Dalby KN, Anslyn EV. Differential sensing of MAP kinases using SOX-peptides. Angewandte Chemie (International Ed. in English). 53: 14064-8. PMID 25319433 DOI: 10.1002/Anie.201408256 |
0.701 |
|
| 2014 |
Devkota AK, Edupuganti R, Yan C, Shi Y, Jose J, Wang Q, Kaoud TS, Cho EJ, Ren P, Dalby KN. Reversible covalent inhibition of eEF-2K by carbonitriles. Chembiochem : a European Journal of Chemical Biology. 15: 2435-42. PMID 25224652 DOI: 10.1002/Cbic.201402321 |
0.818 |
|
| 2014 |
Radwan MF, Dalby KN, Kaoud TS. Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors. Acs Medicinal Chemistry Letters. 5: 983-8. PMID 25221653 DOI: 10.1021/ml500156v |
0.49 |
|
| 2014 |
Tavares CDJ, Jose J, Devkota AK, Park J, Kaoud TS, Anslyn EV, Dalby KN. Abstract 5462: Antiproliferative and cytotoxic activities of 5-(nonyloxy)tryptamine derivatives in breast cancer cells Cancer Research. 74: 5462-5462. DOI: 10.1158/1538-7445.Am2014-5462 |
0.804 |
|
| 2014 |
Park J, Wang Q, Kaoud TS, Tavares CDJ, Edupuganti R, Ren P, Dalby KN. Abstract 513: Investigating stress-response pathways in pancreatic cancer cells using novel PERK inhibitors Cancer Research. 74: 513-513. DOI: 10.1158/1538-7445.Am2014-513 |
0.829 |
|
| 2014 |
Zamora-Olivares D, Kaoud TS, Jose J, Ellington A, Dalby KN, Anslyn EV. Differential sensing of MAP kinases using SOX-peptides Angewandte Chemie - International Edition. 53: 14064-14068. DOI: 10.1002/anie.201408256 |
0.552 |
|
| 2013 |
Kook S, Zhan X, Kaoud TS, Dalby KN, Gurevich VV, Gurevich EV. Arrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding. The Journal of Biological Chemistry. 288: 37332-42. PMID 24257757 DOI: 10.1074/Jbc.M113.510412 |
0.664 |
|
| 2013 |
Zamora-Olivares D, Kaoud TS, Dalby KN, Anslyn EV. In-situ generation of differential sensors that fingerprint kinases and the cellular response to their expression Journal of the American Chemical Society. 135: 14814-14820. PMID 23991633 DOI: 10.1021/Ja407397Z |
0.642 |
|
| 2013 |
Zhan X, Kaoud TS, Kook S, Dalby KN, Gurevich VV. JNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinases. The Journal of Biological Chemistry. 288: 28535-47. PMID 23960075 DOI: 10.1074/Jbc.M113.508085 |
0.665 |
|
| 2013 |
Madsen JA, Xu H, Robinson MR, Horton AP, Shaw JB, Giles DK, Kaoud TS, Dalby KN, Trent MS, Brodbelt JS. High-throughput database search and large-scale negative polarity liquid chromatography-tandem mass spectrometry with ultraviolet photodissociation for complex proteomic samples. Molecular & Cellular Proteomics : McP. 12: 2604-14. PMID 23695934 DOI: 10.1074/Mcp.O113.028258 |
0.687 |
|
| 2013 |
Li J, Kaoud TS, Levieux J, Gilbreath B, Moharana S, Dalby KN, Kerwin SM. A Fluorescence-Based Assay for p38α Recruitment Site Binders: Identification of Rooperol as a Novel p38α Kinase Inhibitor Chembiochem. 14: 66-71. PMID 23225637 DOI: 10.1002/Cbic.201200529 |
0.564 |
|
| 2013 |
Kaoud TS, Park J, Mitra S, Tavares CDJ, Tseng A, Dalby KN. Abstract 4551: Identification of TRPM7 kinase inhibitors. Cancer Research. 73: 4551-4551. DOI: 10.1158/1538-7445.Am2013-4551 |
0.83 |
|
| 2013 |
Xie X, Kaoud TS, Edupuganti R, Sammons RM, Hortobagyi GN, Ueno NT, Dalby KN, Bartholomeusz C. Abstract 3241: Preclinical development of JNK-targeted therapy for triple-negative breast cancer. Cancer Research. 73: 3241-3241. DOI: 10.1158/1538-7445.Am2013-3241 |
0.776 |
|
| 2013 |
Tavares CDJ, Ferguson SB, Wellmann RM, Kaoud TS, O'Brien JP, Ozpolat B, Brodbelt JS, Dalby KN. Abstract 2222: Analysis of the autophosphorylation-induced calcium-independent activity of human elongation factor 2 kinase (eEF-2K) - a therapeutic target for breast cancer. Cancer Research. 73: 2222-2222. DOI: 10.1158/1538-7445.Am2013-2222 |
0.832 |
|
| 2012 |
Kaoud TS, Yan C, Mitra S, Tseng CC, Jose J, Taliaferro JM, Tuohetahuntila M, Devkota A, Sammons R, Park J, Park H, Shi Y, Hong J, Ren P, Dalby KN. From in Silico Discovery to intra-Cellular Activity: Targeting JNK-Protein Interactions with Small Molecules. Acs Medicinal Chemistry Letters. 3: 721-725. PMID 23002419 DOI: 10.1021/Ml300129B |
0.819 |
|
| 2012 |
Kaoud TS, Park H, Mitra S, Yan C, Tseng CC, Shi Y, Jose J, Taliaferro JM, Lee K, Ren P, Hong J, Dalby KN. Manipulating JNK signaling with (--)-zuonin A. Acs Chemical Biology. 7: 1873-83. PMID 22916726 DOI: 10.1021/Cb300261E |
0.848 |
|
| 2012 |
Tekedereli I, Alpay SN, Tavares CD, Cobanoglu ZE, Kaoud TS, Sahin I, Sood AK, Lopez-Berestein G, Dalby KN, Ozpolat B. Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer. Plos One. 7: e41171. PMID 22911754 DOI: 10.1371/Journal.Pone.0041171 |
0.808 |
|
| 2012 |
Madsen JA, Cheng RR, Kaoud TS, Dalby KN, Makarov DE, Brodbelt JS. Charge-site-dependent dissociation of hydrogen-rich radical peptide cations upon vacuum UV photoexcitation. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 5374-83. PMID 22431222 DOI: 10.1002/Chem.201103534 |
0.521 |
|
| 2012 |
Devkota AK, Tavares CD, Warthaka M, Abramczyk O, Marshall KD, Kaoud TS, Gorgulu K, Ozpolat B, Dalby KN. Investigating the kinetic mechanism of inhibition of elongation factor 2 kinase by NH125: evidence of a common in vitro artifact. Biochemistry. 51: 2100-12. PMID 22352903 DOI: 10.1021/Bi201787P |
0.821 |
|
| 2012 |
Tavares CD, O'Brien JP, Abramczyk O, Devkota AK, Shores KS, Ferguson SB, Kaoud TS, Warthaka M, Marshall KD, Keller KM, Zhang Y, Brodbelt JS, Ozpolat B, Dalby KN. Calcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependence. Biochemistry. 51: 2232-45. PMID 22329831 DOI: 10.1021/Bi201788E |
0.795 |
|
| 2012 |
Schnieders MJ, Kaoud TS, Yan C, Dalby KN, Ren P. Computational insights for the discovery of non-ATP competitive inhibitors of MAP kinases. Current Pharmaceutical Design. 18: 1173-85. PMID 22316156 DOI: 10.2174/138920012799362873 |
0.638 |
|
| 2012 |
Kaoud TS, Yan C, Tseng C, Jose J, Devkota AK, Taliaferro J, Ren P, Dalby K. Abstract 4776: From in-silico screening to anti-cancer activity: The discovery of a potent inhibitor targeting the JNK-JIP interaction Cancer Research. 72: 4776-4776. DOI: 10.1158/1538-7445.Am2012-4776 |
0.839 |
|
| 2011 |
Zhan X, Kaoud TS, Dalby KN, Gurevich VV. Nonvisual arrestins function as simple scaffolds assembling the MKK4-JNK3α2 signaling complex. Biochemistry. 50: 10520-9. PMID 22047447 DOI: 10.1021/Bi201506G |
0.663 |
|
| 2011 |
Lee S, Warthaka M, Yan C, Kaoud TS, Ren P, Dalby KN. Examining docking interactions on ERK2 with modular peptide substrates. Biochemistry. 50: 9500-10. PMID 21955038 DOI: 10.1021/Bi201103B |
0.822 |
|
| 2011 |
Kaoud TS, Devkota AK, Harris R, Rana MS, Abramczyk O, Warthaka M, Lee S, Girvin ME, Riggs AF, Dalby KN. Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15. Biochemistry. 50: 4568-78. PMID 21506533 DOI: 10.1021/Bi200202Y |
0.776 |
|
| 2011 |
Lee S, Warthaka M, Yan C, Kaoud TS, Piserchio A, Ghose R, Ren P, Dalby KN. A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach. Plos One. 6: e18594. PMID 21494553 DOI: 10.1371/Journal.Pone.0018594 |
0.804 |
|
| 2011 |
Piserchio A, Warthaka M, Devkota AK, Kaoud TS, Lee S, Abramczyk O, Ren P, Dalby KN, Ghose R. Solution NMR insights into docking interactions involving inactive ERK2. Biochemistry. 50: 3660-72. PMID 21449613 DOI: 10.1021/Bi2000559 |
0.801 |
|
| 2011 |
Kaoud TS, Mitra S, Lee S, Taliaferro J, Cantrell M, Linse KD, Van Den Berg CL, Dalby KN. Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration. Acs Chemical Biology. 6: 658-66. PMID 21438496 DOI: 10.1021/Cb200017N |
0.82 |
|
| 2011 |
Madsen JA, Kaoud TS, Dalby KN, Brodbelt JS. 193-nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization. Proteomics. 11: 1329-34. PMID 21365762 DOI: 10.1002/Pmic.201000565 |
0.495 |
|
| 2011 |
Yan C, Kaoud T, Lee S, Dalby KN, Ren P. Understanding the specificity of a docking interaction between JNK1 and the scaffolding protein JIP1. The Journal of Physical Chemistry. B. 115: 1491-502. PMID 21261310 DOI: 10.1021/Jp1073522 |
0.814 |
|
| 2010 |
Devkota AK, Kaoud TS, Warthaka M, Dalby KN. Fluorescent peptide assays for protein kinases. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 18.17. PMID 20583097 DOI: 10.1002/0471142727.Mb1817S91 |
0.825 |
|
| 2009 |
Li J, Kaoud TS, Laroche C, Dalby KN, Kerwin SM. Synthesis and biological evaluation of p38α kinase-targeting dialkynylimidazoles Bioorganic and Medicinal Chemistry Letters. 19: 6293-6297. PMID 19822424 DOI: 10.1016/J.Bmcl.2009.09.094 |
0.634 |
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| Show low-probability matches. |