Year |
Citation |
Score |
2023 |
Bustos VH, Sunkari YK, Sinha A, Pulina M, Bispo A, Hopkins M, Lam A, Kriegsman SF, Mui E, Chang E, Jedlicki A, Rosenthal H, Flajolet M, Sinha SC. Rational Development of a Small-Molecule Activator of CK1γ2 That Decreases C99 and Beta-Amyloid Levels. Acs Chemical Biology. PMID 38079390 DOI: 10.1021/acschembio.3c00425 |
0.521 |
|
2021 |
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Bustos V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280 |
0.398 |
|
2021 |
Ledo JH, Zhang R, Mesin L, Mourão-Sá D, Azevedo EP, Silva HM, Troyanskaya OG, Bustos V, Greengard P. Correction: Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development. Plos One. 16: e0247680. PMID 33606833 DOI: 10.1371/journal.pone.0247680 |
0.726 |
|
2020 |
Bustos V, Pulina MV, Ledo J. Amyloidogenic and anti-amyloidogenic properties of presenilin 1. Advances in Pharmacology (San Diego, Calif.). 90: 239-251. PMID 33706935 DOI: 10.1016/bs.apha.2020.09.010 |
0.794 |
|
2020 |
Ledo JH, Zhang R, Mesin L, Mourão-Sá D, Azevedo EP, Troyanskaya OG, Bustos V, Greengard P. Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development. Plos One. 15: e0237773. PMID 32822378 DOI: 10.1371/Journal.Pone.0237773 |
0.751 |
|
2020 |
Ledo JH, Liebmann T, Zhang R, Chang JC, Azevedo EP, Wong E, Silva HM, Troyanskaya OG, Bustos V, Greengard P. Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia. Molecular Psychiatry. PMID 32792660 DOI: 10.1038/S41380-020-0856-8 |
0.817 |
|
2020 |
Luo W, Ip FCF, Fu G, Cheung K, Tian Y, Hu Y, Sinha A, Cheng EYL, Wu X, Bustos V, Greengard P, Li YM, Sinha SC, Ip NY. A pentacyclic triterpene from targets γ-secretase. Acs Chemical Neuroscience. PMID 32786303 DOI: 10.1021/Acschemneuro.0C00389 |
0.644 |
|
2020 |
Rodríguez-Lavado J, Gallardo-Garrido C, Mallea M, Bustos V, Osorio R, Hödar-Salazar M, Chung H, Araya-Maturana R, Lorca M, Pessoa-Mahana CD, Mella-Raipán J, Saitz C, Jaque P, Reyes-Parada M, Iturriaga-Vásquez P, et al. Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease. European Journal of Medicinal Chemistry. 198: 112368. PMID 32388114 DOI: 10.1016/J.Ejmech.2020.112368 |
0.346 |
|
2019 |
Pulina MV, Hopkins M, Haroutunian V, Greengard P, Bustos V. C99 selectively accumulates in vulnerable neurons in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31677937 DOI: 10.1016/J.Jalz.2019.09.002 |
0.705 |
|
2017 |
Bustos V, Pulina MV, Kelahmetoglu Y, Sinha SC, Gorelick FS, Flajolet M, Greengard P. Bidirectional regulation of Aβ levels by Presenilin 1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533411 DOI: 10.1073/Pnas.1705235114 |
0.668 |
|
2017 |
Bustos V, Pulina MV, Bispo A, Lam A, Flajolet M, Gorelick FS, Greengard P. Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533369 DOI: 10.1073/Pnas.1705240114 |
0.676 |
|
2017 |
Netzer WJ, Bettayeb K, Sinha SC, Flajolet M, Greengard P, Bustos V. Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115709 DOI: 10.1073/Pnas.1620963114 |
0.701 |
|
2015 |
Ceglia I, Reitz C, Gresack J, Ahn JH, Bustos V, Bleck M, Zhang X, Martin G, Simon SM, Nairn AC, Greengard P, Kim Y. APP intracellular domain-WAVE1 pathway reduces amyloid-β production. Nature Medicine. PMID 26280122 DOI: 10.1038/Nm.3924 |
0.716 |
|
2013 |
Steele JW, Fan E, Kelahmetoglu Y, Tian Y, Bustos V. Modulation of Autophagy as a Therapeutic Target for Alzheimer's Disease. Postdoc Journal : a Journal of Postdoctoral Research and Postdoctoral Affairs. 1: 21-34. PMID 28286801 |
0.646 |
|
2013 |
Zhu L, Zhong M, Zhao J, Rhee H, Caesar I, Knight EM, Volpicelli-Daley L, Bustos V, Netzer W, Liu L, Lucast L, Ehrlich ME, Robakis NK, Gandy SE, Cai D. Reduction of synaptojanin 1 accelerates Aβ clearance and attenuates cognitive deterioration in an Alzheimer mouse model. The Journal of Biological Chemistry. 288: 32050-63. PMID 24052255 DOI: 10.1074/Jbc.M113.504365 |
0.562 |
|
2013 |
Steele JW, Fan E, Kelahmetoglu Y, Tian Y, Bustos V. Modulation of Autophagy as a Therapeutic Target for Alzheimer’s Disease Postdoc Journal. 1: 21-34. DOI: 10.14304/Surya.Jpr.V1N2.3 |
0.651 |
|
2012 |
Bettayeb K, Oumata N, Zhang Y, Luo W, Bustos V, Galons H, Greengard P, Meijer L, Flajolet M. Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 5115-23. PMID 22972917 DOI: 10.1096/Fj.12-212985 |
0.672 |
|
2011 |
Tian Y, Bustos V, Flajolet M, Greengard P. A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1934-42. PMID 21368103 DOI: 10.1096/Fj.10-175158 |
0.68 |
|
2011 |
Venerando A, Marin O, Cozza G, Bustos VH, Sarno S, Pinna LA. Erratum to: Isoform specific phosphorylation of p53 by protein kinase CK1 Cellular and Molecular Life Sciences. 68: 919-919. DOI: 10.1007/S00018-010-0622-1 |
0.353 |
|
2010 |
Venerando A, Marin O, Cozza G, Bustos VH, Sarno S, Pinna LA. Isoform specific phosphorylation of p53 by protein kinase CK1. Cellular and Molecular Life Sciences : Cmls. 67: 1105-18. PMID 20041275 DOI: 10.1007/S00018-009-0236-7 |
0.393 |
|
2007 |
Ferrarese A, Marin O, Bustos VH, Venerando A, Antonelli M, Allende JE, Pinna LA. Chemical dissection of the APC Repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3. Biochemistry. 46: 11902-10. PMID 17910481 DOI: 10.1021/Bi701674Z |
0.418 |
|
2007 |
Coluccia AM, Vacca A, Duñach M, Mologni L, Redaelli S, Bustos VH, Benati D, Pinna LA, Gambacorti-Passerini C. Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation. The Embo Journal. 26: 1456-66. PMID 17318191 DOI: 10.1038/Sj.Emboj.7601485 |
0.401 |
|
2006 |
Bustos VH, Ferrarese A, Venerando A, Marin O, Allende JE, Pinna LA. The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1. Proceedings of the National Academy of Sciences of the United States of America. 103: 19725-30. PMID 17172446 DOI: 10.1073/Pnas.0609424104 |
0.344 |
|
2005 |
Bustos VH, Marin O, Meggio F, Cesaro L, Allende CC, Allende JE, Pinna LA. Generation of protein kinase Ck1alpha mutants which discriminate between canonical and non-canonical substrates. The Biochemical Journal. 391: 417-24. PMID 15975091 DOI: 10.1042/Bj20050717 |
0.416 |
|
2005 |
Sobrado P, Jedlicki A, Bustos VH, Allende CC, Allende JE. Basic region of residues 228-231 of protein kinase CK1alpha is involved in its interaction with axin: binding to axin does not affect the kinase activity. Journal of Cellular Biochemistry. 94: 217-24. PMID 15565646 DOI: 10.1002/Jcb.20350 |
0.387 |
|
2003 |
Marin O, Bustos VH, Cesaro L, Meggio F, Pagano MA, Antonelli M, Allende CC, Pinna LA, Allende JE. A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins. Proceedings of the National Academy of Sciences of the United States of America. 100: 10193-200. PMID 12925738 DOI: 10.1073/Pnas.1733909100 |
0.368 |
|
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