Angus C. Nairn - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
dopamine,basal ganglia

415 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Montalban E, Giralt A, Taing L, Schut EHS, Supiot LF, Castell L, Nakamura Y, de Pins B, Pelosi A, Goutebroze L, Tuduri P, Wang W, Neiburga KD, Vestito L, Castel J, ... ... Nairn AC, et al. Translational profiling of mouse dopaminoceptive neurons reveals region-specific gene expression, exon usage, and striatal prostaglandin E2 modulatory effects. Molecular Psychiatry. PMID 35177825 DOI: 10.1038/s41380-022-01439-4  0.674
2021 Lee AM, Mansuri MS, Wilson RS, Lam TT, Nairn AC, Picciotto MR. Sex Differences in the Ventral Tegmental Area and Nucleus Accumbens Proteome at Baseline and Following Nicotine Exposure. Frontiers in Molecular Neuroscience. 14: 657064. PMID 34335180 DOI: 10.3389/fnmol.2021.657064  0.607
2021 Xu P, Chang JC, Zhou X, Wang W, Bamkole M, Wong E, Bettayeb K, Jiang LL, Huang T, Luo W, Xu H, Nairn AC, Flajolet M, Ip NY, Li YM, et al. GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. The Journal of Experimental Medicine. 218. PMID 34156424 DOI: 10.1084/jem.20202446  0.595
2021 Foley K, McKee C, Nairn AC, Xia H. Regulation of Synaptic Transmission and Plasticity by Protein Phosphatase 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 41: 3040-3050. PMID 33827970 DOI: 10.1523/JNEUROSCI.2026-20.2021  0.557
2021 Girault JA, Nairn AC. DARPP-32 40 years later. Advances in Pharmacology (San Diego, Calif.). 90: 67-87. PMID 33706939 DOI: 10.1016/bs.apha.2020.09.004  0.636
2021 Christensen KR, Nairn AC. cAMP-regulated phosphoproteins DARPP-32, ARPP16/19, and RCS modulate striatal signal transduction through protein kinases and phosphatases. Advances in Pharmacology (San Diego, Calif.). 90: 39-65. PMID 33706938 DOI: 10.1016/bs.apha.2020.09.005  0.374
2020 Li X, Terunuma M, Deeb TG, Wiseman S, Pangalos MN, Nairn AC, Moss SJ, Slesinger PA. Direct interaction of PP2A phosphatase with GABA receptors alters functional signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32111696 DOI: 10.1523/Jneurosci.2654-19.2020  0.785
2020 Datta D, Leslie SN, Morozov YM, Duque A, Rakic P, van Dyck CH, Nairn AC, Arnsten AFT. Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex. Journal of Neuroinflammation. 17: 8. PMID 31906973 DOI: 10.1186/s12974-019-1683-1  0.306
2019 Arnsten AFT, Datta D, Leslie S, Yang ST, Wang M, Nairn AC. Alzheimer's-like pathology in aging rhesus macaques: Unique opportunity to study the etiology and treatment of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871209 DOI: 10.1073/Pnas.1903671116  0.328
2019 Wilson RS, Rauniyar N, Sakaue F, Lam TT, Williams KR, Nairn AC. Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD). Proteomes. 7. PMID 30986977 DOI: 10.3390/Proteomes7020012  0.366
2019 Leslie SN, Nairn AC. cAMP regulation of protein phosphatases PP1 and PP2A in brain. Biochimica Et Biophysica Acta. Molecular Cell Research. 1866: 64-73. PMID 30401536 DOI: 10.1016/j.bbamcr.2018.09.006  0.488
2019 Yim YY, Browne CJ, Wang J, Wilson RS, Nairn AC, Dong Y, Nestler EJ. Proteomic profiling of nucleus accumbens synaptosomes following short- and long-term withdrawal from cocaine self-administration in mice Ibro Reports. 6: S371. DOI: 10.1016/j.ibror.2019.07.1178  0.42
2018 Torregrossa MM, MacDonald M, Stone KL, Lam TT, Nairn AC, Taylor JR. Phosphoproteomic analysis of cocaine memory extinction and reconsolidation in the nucleus accumbens. Psychopharmacology. PMID 30411139 DOI: 10.1007/S00213-018-5071-9  0.485
2018 Miller MB, Wilson RS, Lam TT, Nairn AC, Picciotto MR. Evaluation of the Phosphoproteome of Mouse Alpha 4/Beta 2-Containing Nicotinic Acetylcholine Receptors In Vitro and In Vivo. Proteomes. 6. PMID 30326594 DOI: 10.3390/Proteomes6040042  0.664
2018 Bertholomey ML, Stone K, Lam TT, Bang S, Wu W, Nairn AC, Taylor JR, Torregrossa MM. Phosphoproteomic Analysis of the Amygdala Response to Adolescent Glucocorticoid Exposure Reveals G-Protein Coupled Receptor Kinase 2 as a Target for Reducing Motivation for Alcohol. Proteomes. 6. PMID 30322021 DOI: 10.3390/Proteomes6040041  0.525
2018 Rapanelli M, Frick L, Jindachomthong K, Xu J, Ohtsu H, Nairn A, Pittenger C. Striatal signaling regulated by the H3R histamine receptor in a mouse model of tic pathophysiology. Neuroscience. PMID 30278251 DOI: 10.1016/j.neuroscience.2018.09.035  0.367
2018 Li D, Musante V, Zhou WL, Picciotto MR, Nairn AC. Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons. The Journal of Biological Chemistry. PMID 29802198 DOI: 10.1074/jbc.RA117.001519  0.681
2018 Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn AC, Norris CM, Ferland G, Bézard E, Gaudreau P, Lombroso PJ, Brouillette J. The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline. Current Biology : Cb. PMID 29576474 DOI: 10.1016/J.Cub.2018.02.047  0.553
2018 Madero-Pérez J, Fdez E, Fernández B, Lara Ordóñez AJ, Blanca Ramírez M, Gómez-Suaga P, Waschbüsch D, Lobbestael E, Baekelandt V, Nairn AC, Ruiz-Martínez J, Aiastui A, López de Munain A, Lis P, Comptdaer T, et al. Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation. Molecular Neurodegeneration. 13: 3. PMID 29357897 DOI: 10.1186/S13024-018-0235-Y  0.381
2017 Tjin CC, Otley KD, Baguley TD, Kurup P, Xu J, Nairn AC, Lombroso PJ, Ellman JA. Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases. Acs Central Science. 3: 1322-1328. PMID 29296673 DOI: 10.1021/Acscentsci.7B00486  0.647
2017 Carlyle BC, Kitchen RR, Kanyo JE, Voss EZ, Pletikos M, Sousa AMM, Lam TT, Gerstein MB, Sestan N, Nairn AC. A multiregional proteomic survey of the postnatal human brain. Nature Neuroscience. 20: 1787-1795. PMID 29184206 DOI: 10.1038/S41593-017-0011-2  0.309
2017 Witten MR, Wissler L, Snow M, Geschwindner S, Read JA, Brandon NJ, Nairn AC, Lombroso PJ, Käck H, Ellman JA. X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors. Journal of Medicinal Chemistry. PMID 29116812 DOI: 10.1021/Acs.Jmedchem.7B01292  0.61
2017 Chiba K, Chien KY, Sobu Y, Hata S, Kato S, Nakaya T, Okada Y, Nairn AC, Kinjo M, Taru H, Wang R, Suzuki T. Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1. Molecular Biology of the Cell. PMID 29093025 DOI: 10.1091/Mbc.E17-05-0303  0.551
2017 Sobu Y, Furukori K, Chiba K, Nairn AC, Kinjo M, Hata S, Suzuki T. Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo. Molecular Biology of the Cell. PMID 29093024 DOI: 10.1091/Mbc.E17-05-0301  0.556
2017 Pradhan S, Khatlani T, Nairn AC, Vijayan KV. The heterotrimeric G protein Gβ1 interacts with the catalytic subunit of protein phosphatase 1 and modulates G protein coupled receptor signaling in platelets. The Journal of Biological Chemistry. PMID 28615442 DOI: 10.1074/jbc.M117.796656  0.38
2017 Musante V, Li L, Kanyo J, Lam TT, Colangelo CM, Cheng SK, Brody H, Greengard P, Le Novère N, Nairn AC. Reciprocal regulation of ARPP-16 by PKA and MAST-3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. Elife. 6. PMID 28613156 DOI: 10.7554/Elife.24998  0.632
2017 Xu J, Kurup P, Nairn AC, Lombroso PJ. Synaptic NMDA Receptor Activation Induces Ubiquitination and Degradation of STEP61. Molecular Neurobiology. PMID 28466270 DOI: 10.1007/s12035-017-0555-x  0.593
2017 Andrade EC, Musante V, Horiuchi A, Matsuzaki H, Brody AH, Wu T, Greengard P, Taylor JR, Nairn AC. ARPP-16 is a striatal-enriched inhibitor of protein phosphatase 2A regulated by microtubule-associated serine/threonine kinase 3 (Mast 3 kinase). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28167675 DOI: 10.1523/JNEUROSCI.4559-15.2017  0.85
2017 Ceglia I, Lee KW, Cahill ME, Graves SM, Dietz D, Surmeier DJ, Nestler EJ, Nairn AC, Greengard P, Kim Y. WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115704 DOI: 10.1073/Pnas.1621185114  0.58
2017 Musante V, Li L, Kanyo J, Lam TT, Colangelo CM, Cheng SK, Brody AH, Greengard P, Novère NL, Nairn AC. Author response: Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition Elife. DOI: 10.7554/Elife.24998.035  0.567
2017 Girault J-, Greengard P, Nairn AC. Regulation of Striatal Signaling by Protein Phosphatases Handbook of Behavioral Neuroscience. 24: 583-607. DOI: 10.1016/B978-0-12-802206-1.00029-5  0.538
2016 Lombroso PJ, Ogren M, Kurup P, Nairn AC. Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity. F1000research. 5. PMID 29098072 DOI: 10.12688/f1000research.8571.1  0.602
2016 Nishi A, Matamales M, Musante V, Valjent E, Kuroiwa M, Kitahara Y, Rebholz H, Greengard P, Girault JA, Nairn AC. Glutamate counteracts dopamine/PKA signaling via dephosphorylation of DARPP-32 Ser97 and alteration of its cytonuclear distribution. The Journal of Biological Chemistry. PMID 27998980 DOI: 10.1074/jbc.M116.752402  0.689
2016 Xu J, Hartley BJ, Kurup P, Phillips A, Topol A, Xu M, Ononenyi C, Foscue E, Ho SM, Baguley TD, Carty N, Barros CS, Müller U, Gupta S, Gochman P, ... ... Nairn AC, et al. Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models. Molecular Psychiatry. PMID 27752082 DOI: 10.1038/mp.2016.163  0.609
2016 Rapanelli M, Frick LR, Horn KD, Schwarcz R, Pogorelov V, Nairn AC, Pittenger C. The histamine H3 receptor differentially modulates MAPK and Akt signaling in striatonigral and striatopallidal neurons. The Journal of Biological Chemistry. PMID 27510032 DOI: 10.1074/jbc.M116.731406  0.381
2016 Rich MT, Abbott TB, Chung L, Gulcicek EE, Stone KL, Colangelo CM, Lam TT, Nairn AC, Taylor JR, Torregrossa MM. Phosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIα Regulation Inversely Induced by Cocaine Memory Extinction versus Reconsolidation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7613-27. PMID 27445140 DOI: 10.1523/Jneurosci.1108-16.2016  0.531
2016 Kamceva M, Benedict J, Nairn AC, Lombroso PJ. Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function. Neural Plasticity. 2016: 8136925. PMID 27190655 DOI: 10.1155/2016/8136925  0.607
2015 Engmann O, Giralt A, Gervasi N, Marion-Poll L, Gasmi L, Filhol O, Picciotto MR, Gilligan D, Greengard P, Nairn AC, Hervé D, Girault JA. DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons. Nature Communications. 6: 10099. PMID 26639316 DOI: 10.1038/ncomms10099  0.802
2015 Yang H, Hou H, Pahng A, Gu H, Nairn AC, Tang YP, Colombo PJ, Xia H. Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15082-7. PMID 26558779 DOI: 10.1523/Jneurosci.1865-15.2015  0.568
2015 Xu J, Kurup P, Baguley TD, Foscue E, Ellman JA, Nairn AC, Lombroso PJ. Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice. Cellular and Molecular Life Sciences : Cmls. PMID 26450419 DOI: 10.1007/S00018-015-2057-1  0.576
2015 Liu R, Correll RN, Davis J, Vagnozzi RJ, York AJ, Sargent MA, Nairn AC, Molkentin JD. Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations. Journal of Molecular and Cellular Cardiology. 87: 204-13. PMID 26334248 DOI: 10.1016/J.Yjmcc.2015.08.018  0.363
2015 Yamagata Y, Nairn AC. Contrasting features of ERK1/2 activity and synapsin I phosphorylation at the ERK1/2-dependent site in the rat brain in status epilepticus induced by kainic acid in vivo. Brain Research. 1625: 314-23. PMID 26320550 DOI: 10.1016/j.brainres.2015.08.023  0.452
2015 Xu J, Kurup P, Azkona G, Baguley TD, Saavedra A, Nairn AC, Ellman JA, Pérez-Navarro E, Lombroso PJ. Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels. Journal of Neurochemistry. PMID 26316048 DOI: 10.1111/Jnc.13295  0.612
2015 Ceglia I, Reitz C, Gresack J, Ahn JH, Bustos V, Bleck M, Zhang X, Martin G, Simon SM, Nairn AC, Greengard P, Kim Y. APP intracellular domain-WAVE1 pathway reduces amyloid-β production. Nature Medicine. PMID 26280122 DOI: 10.1038/Nm.3924  0.739
2015 Plattner F, Hayashi K, Hernández A, Benavides DR, Tassin TC, Tan C, Day J, Fina MW, Yuen EY, Yan Z, Goldberg MS, Nairn AC, Greengard P, Nestler EJ, Taussig R, et al. The role of ventral striatal cAMP signaling in stress-induced behaviors. Nature Neuroscience. 18: 1094-100. PMID 26192746 DOI: 10.1038/Nn.4066  0.799
2015 Baguley TD, Nairn AC, Lombroso PJ, Ellman JA. Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP. Bioorganic & Medicinal Chemistry Letters. 25: 1044-6. PMID 25666825 DOI: 10.1016/J.Bmcl.2015.01.020  0.61
2015 Kurup PK, Xu J, Videira RA, Ononenyi C, Baltazar G, Lombroso PJ, Nairn AC. STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 112: 1202-7. PMID 25583483 DOI: 10.1073/pnas.1417423112  0.594
2015 Colangelo CM, Ivosev G, Chung L, Abbott T, Shifman M, Sakaue F, Cox D, Kitchen RR, Burton L, Tate SA, Gulcicek E, Bonner R, Rinehart J, Nairn AC, Williams KR. Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins. Proteomics. 15: 1202-14. PMID 25476245 DOI: 10.1002/Pmic.201400353  0.307
2014 Wan X, Torregrossa MM, Sanchez H, Nairn AC, Taylor JR. Activation of exchange protein activated by cAMP in the rat basolateral amygdala impairs reconsolidation of a memory associated with self-administered cocaine. Plos One. 9: e107359. PMID 25259911 DOI: 10.1371/Journal.Pone.0107359  0.529
2014 Chiba K, Araseki M, Nozawa K, Furukori K, Araki Y, Matsushima T, Nakaya T, Hata S, Saito Y, Uchida S, Okada Y, Nairn AC, Davis RJ, Yamamoto T, Kinjo M, et al. Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport. Molecular Biology of the Cell. 25: 3569-80. PMID 25165140 DOI: 10.1091/Mbc.E14-06-1111  0.514
2014 Xu J, Chatterjee M, Baguley TD, Brouillette J, Kurup P, Ghosh D, Kanyo J, Zhang Y, Seyb K, Ononenyi C, Foscue E, Anderson GM, Gresack J, Cuny GD, Glicksman MA, ... ... Nairn AC, et al. Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. Plos Biology. 12: e1001923. PMID 25093460 DOI: 10.1371/Journal.Pbio.1001923  0.667
2014 Carlyle BC, Nairn AC, Wang M, Yang Y, Jin LE, Simen AA, Ramos BP, Bordner KA, Craft GE, Davies P, Pletikos M, Šestan N, Arnsten AF, Paspalas CD. cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex. Proceedings of the National Academy of Sciences of the United States of America. 111: 5036-41. PMID 24707050 DOI: 10.1073/Pnas.1322360111  0.805
2014 Choy MS, Hieke M, Kumar GS, Lewis GR, Gonzalez-DeWhitt KR, Kessler RP, Stein BJ, Hessenberger M, Nairn AC, Peti W, Page R. Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code. Proceedings of the National Academy of Sciences of the United States of America. 111: 4097-102. PMID 24591642 DOI: 10.1073/Pnas.1317395111  0.43
2014 Dupré A, Daldello EM, Nairn AC, Jessus C, Haccard O. Phosphorylation of ARPP19 by protein kinase A prevents meiosis resumption in Xenopus oocytes. Nature Communications. 5: 3318. PMID 24525567 DOI: 10.1038/ncomms4318  0.495
2013 Hou H, Sun L, Siddoway BA, Petralia RS, Yang H, Gu H, Nairn AC, Xia H. Synaptic NMDA receptor stimulation activates PP1 by inhibiting its phosphorylation by Cdk5. The Journal of Cell Biology. 203: 521-35. PMID 24189275 DOI: 10.1085/Jgp.1426Oia46  0.595
2013 Baguley TD, Xu HC, Chatterjee M, Nairn AC, Lombroso PJ, Ellman JA. Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase. Journal of Medicinal Chemistry. 56: 7636-50. PMID 24083656 DOI: 10.1021/Jm401037H  0.634
2013 Dupré A, Buffin E, Roustan C, Nairn AC, Jessus C, Haccard O. The phosphorylation of ARPP19 by Greatwall renders the auto-amplification of MPF independently of PKA in Xenopus oocytes. Journal of Cell Science. 126: 3916-26. PMID 23781026 DOI: 10.1242/jcs.126599  0.486
2013 Jordi E, Heiman M, Marion-Poll L, Guermonprez P, Cheng SK, Nairn AC, Greengard P, Girault JA. Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 9511-6. PMID 23690581 DOI: 10.1073/pnas.1307116110  0.605
2013 Wiseman SL, Shimizu Y, Palfrey C, Nairn AC. Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase. The Journal of Biological Chemistry. 288: 17803-11. PMID 23640883 DOI: 10.1074/jbc.M113.477182  0.817
2013 Craft GE, Chen A, Nairn AC. Recent advances in quantitative neuroproteomics. Methods (San Diego, Calif.). 61: 186-218. PMID 23623823 DOI: 10.1016/J.Ymeth.2013.04.008  0.792
2013 Yamagata Y, Kaneko K, Kase D, Ishihara H, Nairn AC, Obata K, Imoto K. Regulation of ERK1/2 mitogen-activated protein kinase by NMDA-receptor-induced seizure activity in cortical slices. Brain Research. 1507: 1-10. PMID 23419897 DOI: 10.1016/j.brainres.2013.02.015  0.402
2013 Rebholz H, Zhou M, Nairn AC, Greengard P, Flajolet M. Selective knockout of the casein kinase 2 in d1 medium spiny neurons controls dopaminergic function. Biological Psychiatry. 74: 113-21. PMID 23290496 DOI: 10.1016/j.biopsych.2012.11.013  0.518
2013 Magupalli VG, Mochida S, Yan J, Jiang X, Westenbroek RE, Nairn AC, Scheuer T, Catterall WA. Ca2+-independent activation of Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain of CaV2.1 calcium channels. The Journal of Biological Chemistry. 288: 4637-48. PMID 23255606 DOI: 10.1074/Jbc.M112.369058  0.378
2013 Iketani M, Iizuka A, Sengoku K, Kurihara Y, Nakamura F, Sasaki Y, Sato Y, Yamane M, Matsushita M, Nairn AC, Takamatsu K, Goshima Y, Takei K. Regulation of neurite outgrowth mediated by localized phosphorylation of protein translational factor eEF2 in growth cones. Developmental Neurobiology. 73: 230-46. PMID 23008267 DOI: 10.1002/dneu.22058  0.389
2013 Peti W, Nairn AC, Page R. Structural basis for protein phosphatase 1 regulation and specificity. The Febs Journal. 280: 596-611. PMID 22284538 DOI: 10.1111/J.1742-4658.2012.08509.X  0.425
2012 Peti W, Nairn AC, Page R. Folding of Intrinsically Disordered Protein Phosphatase 1 Regulatory Proteins. Current Physical Chemistry. 2: 107-114. PMID 22866172 DOI: 10.2174/1877946811202010107  0.399
2012 Xu J, Kurup P, Nairn AC, Lombroso PJ. Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease. Advances in Pharmacology (San Diego, Calif.). 64: 303-25. PMID 22840751 DOI: 10.1016/B978-0-12-394816-8.00009-X  0.588
2012 Sathyanesan M, Girgenti MJ, Banasr M, Stone K, Bruce C, Guilchicek E, Wilczak-Havill K, Nairn A, Williams K, Sass S, Duman JG, Newton SS. A molecular characterization of the choroid plexus and stress-induced gene regulation. Translational Psychiatry. 2: e139. PMID 22781172 DOI: 10.1038/Tp.2012.64  0.319
2012 Braithwaite SP, Stock JB, Lombroso PJ, Nairn AC. Protein phosphatases and Alzheimer's disease. Progress in Molecular Biology and Translational Science. 106: 343-79. PMID 22340724 DOI: 10.1016/B978-0-12-396456-4.00012-2  0.656
2012 Davis MM, Olausson P, Greengard P, Taylor JR, Nairn AC. Regulator of calmodulin signaling knockout mice display anxiety-like behavior and motivational deficits. The European Journal of Neuroscience. 35: 300-8. PMID 22250817 DOI: 10.1111/j.1460-9568.2011.07956.x  0.751
2012 Kuroiwa M, Snyder GL, Shuto T, Fukuda A, Yanagawa Y, Benavides DR, Nairn AC, Bibb JA, Greengard P, Nishi A. Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex. Psychopharmacology. 219: 1065-79. PMID 21833500 DOI: 10.1007/S00213-011-2436-8  0.67
2011 Kimura T, Han W, Pagel P, Nairn AC, Caplan MJ. Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin. Plos One. 6: e29269. PMID 22242112 DOI: 10.1371/Journal.Pone.0029269  0.346
2011 Ahn JH, Kim Y, Kim HS, Greengard P, Nairn AC. Protein kinase C-dependent dephosphorylation of tyrosine hydroxylase requires the B56δ heterotrimeric form of protein phosphatase 2A. Plos One. 6: e26292. PMID 22046270 DOI: 10.1371/journal.pone.0026292  0.642
2011 Walaas SI, Hemmings HC, Greengard P, Nairn AC. Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases. Frontiers in Neuroanatomy. 5: 50. PMID 21904525 DOI: 10.3389/fnana.2011.00050  0.776
2011 Zhang Y, Kurup P, Xu J, Anderson GM, Greengard P, Nairn AC, Lombroso PJ. Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization. Journal of Neurochemistry. 119: 664-72. PMID 21883219 DOI: 10.1111/j.1471-4159.2011.07450.x  0.646
2011 Dancheck B, Ragusa MJ, Allaire M, Nairn AC, Page R, Peti W. Molecular investigations of the structure and function of the protein phosphatase 1-spinophilin-inhibitor 2 heterotrimeric complex. Biochemistry. 50: 1238-46. PMID 21218781 DOI: 10.1021/Bi101774G  0.37
2011 Ragusa MJ, Allaire M, Nairn AC, Page R, Peti W. Flexibility in the PP1:spinophilin holoenzyme. Febs Letters. 585: 36-40. PMID 21094159 DOI: 10.1016/J.Febslet.2010.11.022  0.369
2011 Magupalli VG, Jiang X, Westenbroek RE, Scheuer T, Soderling TR, Nairn AC, Catterall WA. Signaling Complex of Calcium/Calmodulin-Dependent Protein Kinase II Associated with the C-Terminal Domain of CaV2.1 Channels Biophysical Journal. 100: 570a-571a. DOI: 10.1016/J.Bpj.2010.12.3305  0.452
2010 Zhang Y, Kurup P, Xu J, Carty N, Fernandez SM, Nygaard HB, Pittenger C, Greengard P, Strittmatter SM, Nairn AC, Lombroso PJ. Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. 107: 19014-9. PMID 20956308 DOI: 10.1073/pnas.1013543107  0.632
2010 McAvoy T, Nairn AC. Serine/threonine protein phosphatase assays. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit18.18. PMID 20890902 DOI: 10.1002/0471142727.mb1818s92  0.349
2010 Flores CE, Cachope R, Nannapaneni S, Ene S, Nairn AC, Pereda AE. Variability of distribution of Ca(2+)/calmodulin-dependent kinase II at mixed synapses on the mauthner cell: colocalization and association with connexin 35. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9488-99. PMID 20631177 DOI: 10.1523/Jneurosci.4466-09.2010  0.361
2010 Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, Nairn AC, Lombroso PJ. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5948-57. PMID 20427654 DOI: 10.1523/JNEUROSCI.0157-10.2010  0.607
2010 Ceglia I, Kim Y, Nairn AC, Greengard P. Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization. Journal of Neurochemistry. 114: 182-90. PMID 20403076 DOI: 10.1111/j.1471-4159.2010.06743.x  0.55
2010 Ragusa MJ, Dancheck B, Critton DA, Nairn AC, Page R, Peti W. Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites. Nature Structural & Molecular Biology. 17: 459-64. PMID 20305656 DOI: 10.1038/Nsmb.1786  0.408
2010 Goffin D, Ali AB, Rampersaud N, Harkavyi A, Fuchs C, Whitton PS, Nairn AC, Jovanovic JN. Dopamine-dependent tuning of striatal inhibitory synaptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2935-50. PMID 20181591 DOI: 10.1523/Jneurosci.4411-09.2010  0.723
2010 Glausier JR, Maddox M, Hemmings HC, Nairn AC, Greengard P, Muly EC. Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex. Neuroscience. 167: 428-38. PMID 20156529 DOI: 10.1016/j.neuroscience.2010.02.014  0.716
2010 Zhou M, Rebholz H, Brocia C, Warner-Schmidt JL, Fienberg AA, Nairn AC, Greengard P, Flajolet M. Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD. Proceedings of the National Academy of Sciences of the United States of America. 107: 4401-6. PMID 20145109 DOI: 10.1073/pnas.0915173107  0.766
2010 Dodge-Kafka KL, Bauman A, Mayer N, Henson E, Heredia L, Ahn J, McAvoy T, Nairn AC, Kapiloff MS. cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3. The Journal of Biological Chemistry. 285: 11078-86. PMID 20106966 DOI: 10.1074/jbc.M109.034868  0.516
2010 McAvoy T, Zhou MM, Greengard P, Nairn AC. Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology (Proceedings National Academy Science USA (2009) 106, (3531-3536) DOI: 10.1073/pnas. 0813263106) Proceedings of the National Academy of Sciences of the United States of America. 107: 8498. DOI: 10.1073/pnas.1003564107  0.392
2010 Fleming MR, Kronengold J, Yan Y, Lam TT, Gulcicek E, Sigworth FJ, Nairn AC, Kaczmarek LK. Identification of Regulatory Phosphorylation Sites in Slack and Slick Sodium Activated Potassium (KNa) Channels Biophysical Journal. 98: 316a. DOI: 10.1016/J.Bpj.2009.12.1714  0.44
2010 Wiseman SL, Wei FY, Nairn AC. The EF2K/MHCK/TRPM7 family of atypical protein kinases Handbook of Cell Signaling, 2/E. 2: 587-599. DOI: 10.1016/B978-0-12-374145-5.00079-6  0.81
2009 Krueger DD, Howell JL, Oo H, Olausson P, Taylor JR, Nairn AC. Prior chronic cocaine exposure in mice induces persistent alterations in cognitive function. Behavioural Pharmacology. 20: 695-704. PMID 19901826 DOI: 10.1097/FBP.0b013e328333a2bb  0.773
2009 Rebholz H, Nishi A, Liebscher S, Nairn AC, Flajolet M, Greengard P. CK2 negatively regulates Galphas signaling. Proceedings of the National Academy of Sciences of the United States of America. 106: 14096-101. PMID 19666609 DOI: 10.1073/Pnas.0906857106  0.589
2009 Hansen C, Howlin J, Tengholm A, Dyachok O, Vogel WF, Nairn AC, Greengard P, Andersson T. Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner. The Journal of Biological Chemistry. 284: 27533-43. PMID 19651774 DOI: 10.1074/Jbc.M109.048884  0.51
2009 Wu JQ, Guo JY, Tang W, Yang CS, Freel CD, Chen C, Nairn AC, Kornbluth S. PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation. Nature Cell Biology. 11: 644-51. PMID 19396163 DOI: 10.1038/Ncb1871  0.495
2009 Cheng L, Pilder S, Nairn AC, Ramdas S, Vijayaraghavan S. PP1gamma2 and PPP1R11 are parts of a multimeric complex in developing testicular germ cells in which their steady state levels are reciprocally related. Plos One. 4: e4861. PMID 19300506 DOI: 10.1371/Journal.Pone.0004861  0.377
2009 Sakuma M, Tanaka E, Taru H, Tomita S, Gandy S, Nairn AC, Nakaya T, Yamamoto T, Suzuki T. Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP. Journal of Neurochemistry. 109: 465-75. PMID 19222704 DOI: 10.1111/J.1471-4159.2009.05988.X  0.568
2009 McAvoy T, Zhou MM, Greengard P, Nairn AC. Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology. Proceedings of the National Academy of Sciences of the United States of America. 106: 3531-6. PMID 19218462 DOI: 10.1073/pnas.0813263106  0.626
2009 Endo S, Shutoh F, Dinh TL, Okamoto T, Ikeda T, Suzuki M, Kawahara S, Yanagihara D, Sato Y, Yamada K, Sakamoto T, Kirino Y, Hartell NA, Yamaguchi K, Itohara S, ... Nairn AC, et al. Dual involvement of G-substrate in motor learning revealed by gene deletion. Proceedings of the National Academy of Sciences of the United States of America. 106: 3525-30. PMID 19218432 DOI: 10.1073/Pnas.0813341106  0.446
2009 Kim Y, Teylan MA, Baron M, Sands A, Nairn AC, Greengard P. Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 106: 2915-20. PMID 19202072 DOI: 10.1073/pnas.0813179106  0.462
2008 Meyer DA, Richer E, Benkovic SA, Hayashi K, Kansy JW, Hale CF, Moy LY, Kim Y, O'Callaghan JP, Tsai LH, Greengard P, Nairn AC, Cowan CW, Miller DB, Antich P, et al. Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology. Proceedings of the National Academy of Sciences of the United States of America. 105: 18561-6. PMID 19017804 DOI: 10.1073/Pnas.0806078105  0.699
2008 Dancheck B, Nairn AC, Peti W. Detailed structural characterization of unbound protein phosphatase 1 inhibitors. Biochemistry. 47: 12346-56. PMID 18954090 DOI: 10.1021/Bi801308Y  0.437
2008 Flajolet M, Wang Z, Futter M, Shen W, Nuangchamnong N, Bendor J, Wallach I, Nairn AC, Surmeier DJ, Greengard P. FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity. Nature Neuroscience. 11: 1402-9. PMID 18953346 DOI: 10.1038/Nn.2216  0.482
2008 Pulipparacharuvil S, Renthal W, Hale CF, Taniguchi M, Xiao G, Kumar A, Russo SJ, Sikder D, Dewey CM, Davis MM, Greengard P, Nairn AC, Nestler EJ, Cowan CW. Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron. 59: 621-33. PMID 18760698 DOI: 10.1016/J.Neuron.2008.06.020  0.7
2008 Han XJ, Lu YF, Li SA, Kaitsuka T, Sato Y, Tomizawa K, Nairn AC, Takei K, Matsui H, Matsushita M. CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology. The Journal of Cell Biology. 182: 573-85. PMID 18695047 DOI: 10.1083/jcb.200802164  0.436
2008 Stipanovich A, Valjent E, Matamales M, Nishi A, Ahn JH, Maroteaux M, Bertran-Gonzalez J, Brami-Cherrier K, Enslen H, Corbillé AG, Filhol O, Nairn AC, Greengard P, Hervé D, Girault JA. A phosphatase cascade by which rewarding stimuli control nucleosomal response. Nature. 453: 879-84. PMID 18496528 DOI: 10.1038/nature06994  0.65
2008 Flynn MP, Maizels ET, Karlsson AB, McAvoy T, Ahn JH, Nairn AC, Hunzicker-Dunn M. Luteinizing hormone receptor activation in ovarian granulosa cells promotes protein kinase A-dependent dephosphorylation of microtubule-associated protein 2D. Molecular Endocrinology (Baltimore, Md.). 22: 1695-710. PMID 18467524 DOI: 10.1210/Me.2007-0457  0.524
2008 Muly EC, Nairn AC, Greengard P, Rainnie DG. Subcellular distribution of the Rho-GEF Lfc in primate prefrontal cortex: effect of neuronal activation. The Journal of Comparative Neurology. 508: 927-39. PMID 18399541 DOI: 10.1002/cne.21703  0.498
2008 Sung JY, Engmann O, Teylan MA, Nairn AC, Greengard P, Kim Y. WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines. Proceedings of the National Academy of Sciences of the United States of America. 105: 3112-6. PMID 18287015 DOI: 10.1073/pnas.0712180105  0.489
2008 Barbano PE, Spivak M, Flajolet M, Nairn AC, Greengard P, Greengard L. A mathematical tool for exploring the dynamics of biological networks (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 49, (19169-19174) DOI: 10.1073/pnas.0709955104) Proceedings of the National Academy of Sciences of the United States of America. 105: 5945. DOI: 10.1073/Pnas.0802451105  0.361
2007 Barbano PE, Spivak M, Flajolet M, Nairn AC, Greengard P, Greengard L. A mathematical tool for exploring the dynamics of biological networks. Proceedings of the National Academy of Sciences of the United States of America. 104: 19169-74. PMID 18032599 DOI: 10.1073/Pnas.0709955104  0.448
2007 Krueger DD, Nairn AC. Expression of PKC substrate proteins, GAP-43 and neurogranin, is downregulated by cAMP signaling and alterations in synaptic activity. The European Journal of Neuroscience. 26: 3043-53. PMID 18005072 DOI: 10.1111/j.1460-9568.2007.05901.x  0.813
2007 Kimura T, Allen PB, Nairn AC, Caplan MJ. Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase. Molecular Biology of the Cell. 18: 4508-18. PMID 17804821 DOI: 10.1091/Mbc.E06-08-0711  0.317
2007 Olausson P, Jentsch JD, Krueger DD, Tronson NC, Nairn AC, Taylor JR. Orbitofrontal cortex and cognitive-motivational impairments in psychostimulant addiction: evidence from experiments in the non-human primate. Annals of the New York Academy of Sciences. 1121: 610-38. PMID 17698993 DOI: 10.1196/annals.1401.016  0.774
2007 Piccoli G, Verpelli C, Tonna N, Romorini S, Alessio M, Nairn AC, Bachi A, Sala C. Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons. Journal of Proteome Research. 6: 3203-15. PMID 17622166 DOI: 10.1021/pr0701308  0.395
2007 Andrade EC, Krueger DD, Nairn AC. Recent advances in neuroproteomics. Current Opinion in Molecular Therapeutics. 9: 270-81. PMID 17608026  0.79
2007 Matsuzaki H, Minabe Y, Nakamura K, Suzuki K, Iwata Y, Sekine Y, Tsuchiya KJ, Sugihara G, Suda S, Takei N, Nakahara D, Hashimoto K, Nairn AC, Mori N, Sato K. Disruption of reelin signaling attenuates methamphetamine-induced hyperlocomotion. The European Journal of Neuroscience. 25: 3376-84. PMID 17553006 DOI: 10.1111/j.1460-9568.2007.05564.x  0.512
2007 Ahn JH, Sung JY, McAvoy T, Nishi A, Janssens V, Goris J, Greengard P, Nairn AC. The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A. Proceedings of the National Academy of Sciences of the United States of America. 104: 9876-81. PMID 17535922 DOI: 10.1073/pnas.0703589104  0.596
2007 Uboha NV, Flajolet M, Nairn AC, Picciotto MR. A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4413-23. PMID 17442826 DOI: 10.1523/Jneurosci.0725-07.2007  0.724
2007 Nguyen C, Nishi A, Kansy JW, Fernandez J, Hayashi K, Gillardon F, Hemmings HC, Nairn AC, Bibb JA. Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5. The Journal of Biological Chemistry. 282: 16511-20. PMID 17400554 DOI: 10.1074/jbc.M701046200  0.784
2007 Flajolet M, He G, Heiman M, Lin A, Nairn AC, Greengard P. Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I. Proceedings of the National Academy of Sciences of the United States of America. 104: 4159-64. PMID 17360493 DOI: 10.1073/pnas.0611236104  0.484
2007 Ahn JH, McAvoy T, Rakhilin SV, Nishi A, Greengard P, Nairn AC. Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit. Proceedings of the National Academy of Sciences of the United States of America. 104: 2979-84. PMID 17301223 DOI: 10.1073/pnas.0611532104  0.625
2007 Iizuka A, Sengoku K, Iketani M, Nakamura F, Sato Y, Matsushita M, Nairn AC, Takamatsu K, Goshima Y, Takei K. Calcium-induced synergistic inhibition of a translational factor eEF2 in nerve growth cones. Biochemical and Biophysical Research Communications. 353: 244-50. PMID 17187762 DOI: 10.1016/j.bbrc.2006.11.150  0.359
2007 Hotte M, Thuault S, Dineley KT, Hemmings HC, Nairn AC, Jay TM. Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo. Synapse (New York, N.Y.). 61: 24-8. PMID 17068779 DOI: 10.1002/syn.20339  0.605
2007 Iizuka A, Iketani M, Sengoku K, Nakamura F, Matsushita M, Nairn A, Goshima Y, Takei K. Calcium dependent-regulation of neurite outgrowth mediated by a protein translational factor eEF2 within nerve growth cones Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.924  0.303
2006 Margolis SS, Perry JA, Forester CM, Nutt LK, Guo Y, Jardim MJ, Thomenius MJ, Freel CD, Darbandi R, Ahn JH, Arroyo JD, Wang XF, Shenolikar S, Nairn AC, Dunphy WG, et al. Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell. 127: 759-73. PMID 17110335 DOI: 10.1016/J.Cell.2006.10.035  0.449
2006 Kanhema T, Dagestad G, Panja D, Tiron A, Messaoudi E, Håvik B, Ying SW, Nairn AC, Sonenberg N, Bramham CR. Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control. Journal of Neurochemistry. 99: 1328-37. PMID 17064361 DOI: 10.1111/J.1471-4159.2006.04158.X  0.424
2006 Mense M, Vergani P, White DM, Altberg G, Nairn AC, Gadsby DC. In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer. The Embo Journal. 25: 4728-39. PMID 17036051 DOI: 10.1038/Sj.Emboj.7601373  0.32
2006 Hansen C, Greengard P, Nairn AC, Andersson T, Vogel WF. Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1. Experimental Cell Research. 312: 4011-8. PMID 17027969 DOI: 10.1016/J.Yexcr.2006.09.003  0.476
2006 Krueger DD, Howell JL, Hebert BF, Olausson P, Taylor JR, Nairn AC. Assessment of cognitive function in the heterozygous reeler mouse. Psychopharmacology. 189: 95-104. PMID 16977475 DOI: 10.1007/s00213-006-0530-0  0.762
2006 Kim Y, Sung JY, Ceglia I, Lee KW, Ahn JH, Halford JM, Kim AM, Kwak SP, Park JB, Ho Ryu S, Schenck A, Bardoni B, Scott JD, Nairn AC, Greengard P. Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology. Nature. 442: 814-7. PMID 16862120 DOI: 10.1038/nature04976  0.519
2006 Braithwaite SP, Paul S, Nairn AC, Lombroso PJ. Synaptic plasticity: one STEP at a time. Trends in Neurosciences. 29: 452-8. PMID 16806510 DOI: 10.1016/j.tins.2006.06.007  0.631
2006 Sahin B, Shu H, Fernandez J, El-Armouche A, Molkentin JD, Nairn AC, Bibb JA. Phosphorylation of protein phosphatase inhibitor-1 by protein kinase C. The Journal of Biological Chemistry. 281: 24322-35. PMID 16772299 DOI: 10.1074/Jbc.M603282200  0.736
2006 Hotte M, Thuault S, Lachaise F, Dineley KT, Hemmings HC, Nairn AC, Jay TM. D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex. Behavioural Brain Research. 171: 127-33. PMID 16687181 DOI: 10.1016/j.bbr.2006.03.026  0.558
2006 Zhang Y, Svenningsson P, Picetti R, Schlussman SD, Nairn AC, Ho A, Greengard P, Kreek MJ. Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2645-51. PMID 16525043 DOI: 10.1523/Jneurosci.3923-05.2006  0.648
2006 Rogers JP, Beuscher AE, Flajolet M, McAvoy T, Nairn AC, Olson AJ, Greengard P. Discovery of protein phosphatase 2C inhibitors by virtual screening. Journal of Medicinal Chemistry. 49: 1658-67. PMID 16509582 DOI: 10.1021/Jm051033Y  0.519
2006 Lee KW, Kim Y, Kim AM, Helmin K, Nairn AC, Greengard P. Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 103: 3399-404. PMID 16492766 DOI: 10.1073/pnas.0511244103  0.465
2006 Rosenberg OS, Deindl S, Comolli LR, Hoelz A, Downing KH, Nairn AC, Kuriyan J. Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II. The Febs Journal. 273: 682-94. PMID 16441656 DOI: 10.1111/J.1742-4658.2005.05088.X  0.706
2006 Scott L, Zelenin S, Malmersjö S, Kowalewski JM, Markus EZ, Nairn AC, Greengard P, Brismar H, Aperia A. Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines. Proceedings of the National Academy of Sciences of the United States of America. 103: 762-7. PMID 16407151 DOI: 10.1073/pnas.0505557103  0.443
2006 Maus M, Torrens Y, Gauchy C, Bretin S, Nairn AC, Glowinski J, Premont J. 2-Deoxyglucose and NMDA inhibit protein synthesis in neurons and regulate phosphorylation of elongation factor-2 by distinct mechanisms. Journal of Neurochemistry. 96: 815-24. PMID 16405506 DOI: 10.1111/j.1471-4159.2005.03601.x  0.483
2006 Zachariou V, Sgambato-Faure V, Sasaki T, Svenningsson P, Berton O, Fienberg AA, Nairn AC, Greengard P, Nestler EJ. Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 555-62. PMID 16123776 DOI: 10.1038/Sj.Npp.1300832  0.656
2005 Svenningsson P, Nairn AC, Greengard P. DARPP-32 mediates the actions of multiple drugs of abuse. The Aaps Journal. 7: E353-60. PMID 16353915 DOI: 10.1208/aapsj070235  0.714
2005 Jin M, Bateup H, Padovan JC, Greengard P, Nairn AC, Chait BT. Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry. Analytical Chemistry. 77: 7845-51. PMID 16351129 DOI: 10.1021/Ac051519M  0.707
2005 Rosenberg OS, Deindl S, Sung RJ, Nairn AC, Kuriyan J. Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme. Cell. 123: 849-60. PMID 16325579 DOI: 10.1016/J.Cell.2005.10.029  0.749
2005 Belelovsky K, Elkobi A, Kaphzan H, Nairn AC, Rosenblum K. A molecular switch for translational control in taste memory consolidation. The European Journal of Neuroscience. 22: 2560-8. PMID 16307598 DOI: 10.1111/J.1460-9568.2005.04428.X  0.418
2005 Uematsu K, Futter M, Hsieh-Wilson LC, Higashi H, Maeda H, Nairn AC, Greengard P, Nishi A. Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways. Journal of Neurochemistry. 95: 1642-52. PMID 16300646 DOI: 10.1111/J.1471-4159.2005.03491.X  0.763
2005 Yeshao W, Gu J, Peng X, Nairn AC, Nadler JL. Elevated glucose activates protein synthesis in cultured cardiac myocytes. Metabolism: Clinical and Experimental. 54: 1453-60. PMID 16253633 DOI: 10.1016/j.metabol.2005.05.010  0.377
2005 Hamada M, Hendrick JP, Ryan GR, Kuroiwa M, Higashi H, Tanaka M, Nairn AC, Greengard P, Nishi A. Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons. The Journal of Pharmacology and Experimental Therapeutics. 315: 872-8. PMID 16040813 DOI: 10.1124/jpet.105.090852  0.571
2005 Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nature Neuroscience. 8: 1051-8. PMID 16025111 DOI: 10.1038/Nn1503  0.714
2005 Ryan XP, Alldritt J, Svenningsson P, Allen PB, Wu GY, Nairn AC, Greengard P. The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology. Neuron. 47: 85-100. PMID 15996550 DOI: 10.1016/j.neuron.2005.05.013  0.615
2005 Matsushita M, Kozak JA, Shimizu Y, McLachlin DT, Yamaguchi H, Wei FY, Tomizawa K, Matsui H, Chait BT, Cahalan MD, Nairn AC. Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. The Journal of Biological Chemistry. 280: 20793-803. PMID 15781465 DOI: 10.1074/Jbc.M413671200  0.628
2005 Bordelon JR, Smith Y, Nairn AC, Colbran RJ, Greengard P, Muly EC. Differential localization of protein phosphatase-1alpha, beta and gamma1 isoforms in primate prefrontal cortex. Cerebral Cortex (New York, N.Y. : 1991). 15: 1928-37. PMID 15758197 DOI: 10.1093/cercor/bhi070  0.517
2005 Hilfiker S, Benfenati F, Doussau F, Nairn AC, Czernik AJ, Augustine GJ, Greengard P. Structural domains involved in the regulation of transmitter release by synapsins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2658-69. PMID 15758176 DOI: 10.1523/Jneurosci.4278-04.2005  0.584
2005 Lee SY, Voronov S, Letinic K, Nairn AC, Di Paolo G, De Camilli P. Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases. The Journal of Cell Biology. 168: 789-99. PMID 15738269 DOI: 10.1083/Jcb.200409028  0.621
2005 Vergani P, Lockless SW, Nairn AC, Gadsby DC. CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains. Nature. 433: 876-80. PMID 15729345 DOI: 10.1038/Nature03313  0.302
2005 Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC. Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5). Proceedings of the National Academy of Sciences of the United States of America. 102: 3489-94. PMID 15728359 DOI: 10.1073/pnas.0409802102  0.721
2005 Takahashi S, Ohshima T, Cho A, Sreenath T, Iadarola MJ, Pant HC, Kim Y, Nairn AC, Brady RO, Greengard P, Kulkarni AB. Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 1737-42. PMID 15665076 DOI: 10.1073/Pnas.0409456102  0.586
2005 Csanády L, Seto-Young D, Chan KW, Cenciarelli C, Angel BB, Qin J, McLachlin DT, Krutchinsky AN, Chait BT, Nairn AC, Gadsby DC. Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA. The Journal of General Physiology. 125: 171-86. PMID 15657296 DOI: 10.1085/Jgp.200409076  0.372
2005 Nishi A, Watanabe Y, Higashi H, Tanaka M, Nairn AC, Greengard P. Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades. Proceedings of the National Academy of Sciences of the United States of America. 102: 1199-204. PMID 15657149 DOI: 10.1073/pnas.0409138102  0.598
2005 Valjent E, Pascoli V, Svenningsson P, Paul S, Enslen H, Corvol JC, Stipanovich A, Caboche J, Lombroso PJ, Nairn AC, Greengard P, Hervé D, Girault JA. Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proceedings of the National Academy of Sciences of the United States of America. 102: 491-6. PMID 15608059 DOI: 10.1073/Pnas.0408305102  0.79
2005 Csanády L, Chan KW, Nairn AC, Gadsby DC. Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain. The Journal of General Physiology. 125: 43-55. PMID 15596536 DOI: 10.1085/Jgp.200409174  0.344
2004 Rakhilin SV, Olson PA, Nishi A, Starkova NN, Fienberg AA, Nairn AC, Surmeier DJ, Greengard P. A network of control mediated by regulator of calcium/calmodulin-dependent signaling. Science (New York, N.Y.). 306: 698-701. PMID 15499021 DOI: 10.1126/Science.1099961  0.619
2004 Nairn AC, Svenningsson P, Nishi A, Fisone G, Girault JA, Greengard P. The role of DARPP-32 in the actions of drugs of abuse. Neuropharmacology. 47: 14-23. PMID 15464122 DOI: 10.1016/J.Neuropharm.2004.05.010  0.778
2004 Sahin B, Kansy JW, Nairn AC, Spychala J, Ealick SE, Fienberg AA, Greene RW, Bibb JA. Molecular characterization of recombinant mouse adenosine kinase and evaluation as a target for protein phosphorylation. European Journal of Biochemistry / Febs. 271: 3547-55. PMID 15317590 DOI: 10.1111/J.1432-1033.2004.04291.X  0.736
2004 Hamada M, Higashi H, Nairn AC, Greengard P, Nishi A. Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons. Journal of Neurochemistry. 90: 1094-103. PMID 15312165 DOI: 10.1111/j.1471-4159.2004.02574.x  0.512
2004 Grossman SD, Futter M, Snyder GL, Allen PB, Nairn AC, Greengard P, Hsieh-Wilson LC. Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin. Journal of Neurochemistry. 90: 317-24. PMID 15228588 DOI: 10.1111/J.1471-4159.2004.02491.X  0.77
2004 Stedman DR, Uboha NV, Stedman TT, Nairn AC, Picciotto MR. Cytoplasmic localization of calcium/calmodulin-dependent protein kinase I-alpha depends on a nuclear export signal in its regulatory domain. Febs Letters. 566: 275-80. PMID 15147908 DOI: 10.1016/J.Febslet.2004.04.042  0.661
2004 Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nature Medicine. 10: 248-54. PMID 14966518 DOI: 10.1038/Nm1000  0.657
2004 Lin TH, Huang YC, Chin ML, Chen YC, Jeng HH, Lin FM, Shiao MS, Horiuchi A, Greengard P, Nairn AC, Huang HB. 1H, 15N, and 13C resonance assignments of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr. 32,000)--a protein inhibitor of protein phosphatase-1. Journal of Biomolecular Nmr. 28: 413-4. PMID 14872138 DOI: 10.1023/B:JNMR.0000015358.20495.b8  0.526
2004 Svenningsson P, Nishi A, Fisone G, Girault JA, Nairn AC, Greengard P. DARPP-32: an integrator of neurotransmission. Annual Review of Pharmacology and Toxicology. 44: 269-96. PMID 14744247 DOI: 10.1146/Annurev.Pharmtox.44.101802.121415  0.781
2004 Lee SY, Wenk MR, Kim Y, Nairn AC, De Camilli P. Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses. Proceedings of the National Academy of Sciences of the United States of America. 101: 546-51. PMID 14704270 DOI: 10.1073/pnas.0307813100  0.634
2003 Fukui R, Svenningsson P, Matsuishi T, Higashi H, Nairn AC, Greengard P, Nishi A. Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice. Journal of Neurochemistry. 87: 1391-401. PMID 14713295 DOI: 10.1046/j.1471-4159.2003.02101.x  0.623
2003 Watanabe T, da Cruz e Silva EF, Huang HB, Starkova N, Kwon YG, Horiuchi A, Greengard P, Nairn AC. Preparation and characterization of recombinant protein phosphatase 1. Methods in Enzymology. 366: 321-38. PMID 14674258 DOI: 10.1016/S0076-6879(03)66024-6  0.72
2003 Flajolet M, Rakhilin S, Wang H, Starkova N, Nuangchamnong N, Nairn AC, Greengard P. Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3. Proceedings of the National Academy of Sciences of the United States of America. 100: 16006-11. PMID 14663150 DOI: 10.1073/pnas.2136600100  0.561
2003 Snyder GL, Galdi S, Fienberg AA, Allen P, Nairn AC, Greengard P. Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists. Neuropharmacology. 45: 703-13. PMID 14529709 DOI: 10.1016/S0028-3908(03)00319-8  0.521
2003 Basso C, Vergani P, Nairn AC, Gadsby DC. Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating. The Journal of General Physiology. 122: 333-48. PMID 12939393 DOI: 10.1085/Jgp.200308798  0.309
2003 Sgambato V, Minassian R, Nairn AC, Hyman SE. Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons. Journal of Neurochemistry. 86: 153-64. PMID 12807435 DOI: 10.1046/J.1471-4159.2003.01816.X  0.44
2003 Hoelz A, Nairn AC, Kuriyan J. Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II. Molecular Cell. 11: 1241-51. PMID 12769848 DOI: 10.1016/S1097-2765(03)00171-0  0.373
2003 Yan L, Nairn AC, Palfrey HC, Brady MJ. Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells. The Journal of Biological Chemistry. 278: 18177-83. PMID 12644453 DOI: 10.1074/jbc.M301116200  0.388
2003 Kim YM, Watanabe T, Allen PB, Kim YM, Lee SJ, Greengard P, Nairn AC, Kwon YG. PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation. The Journal of Biological Chemistry. 278: 13819-28. PMID 12574161 DOI: 10.1074/jbc.M209621200  0.55
2003 Chotiner JK, Khorasani H, Nairn AC, O'Dell TJ, Watson JB. Adenylyl cyclase-dependent form of chemical long-term potentiation triggers translational regulation at the elongation step. Neuroscience. 116: 743-52. PMID 12573716 DOI: 10.1016/S0306-4522(02)00797-2  0.377
2003 Nishi A, Liu F, Matsuyama S, Hamada M, Higashi H, Nairn AC, Greengard P. Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 100: 1322-7. PMID 12538871 DOI: 10.1073/pnas.0237126100  0.505
2003 Endo S, Nairn AC, Greengard P, Ito M. Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor. Neuroscience Research. 45: 79-89. PMID 12507727 DOI: 10.1016/S0168-0102(02)00199-2  0.512
2003 Paul S, Nairn AC, Wang P, Lombroso PJ. NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nature Neuroscience. 6: 34-42. PMID 12483215 DOI: 10.1038/nn989  0.657
2003 Hsieh-Wilson LC, Benfenati F, Snyder GL, Allen PB, Nairn AC, Greengard P. Phosphorylation of spinophilin modulates its interaction with actin filaments. The Journal of Biological Chemistry. 278: 1186-94. PMID 12417592 DOI: 10.1074/Jbc.M205754200  0.799
2003 Nairn AC. Atypical Protein Kinases: The EF2/MHCK/ChaK Kinase Family Handbook of Cell Signaling. 1: 567-573. DOI: 10.1016/B978-012124546-7/50456-3  0.353
2003 Watanabe T, Da Cruz E Silva EF, Huang HB, Starkova N, Kwon YG, Horiuchi A, Greengard P, Nairn AC. [24] Preparation and Characterization of Recombinant Protein Phosphatase 1 Methods in Enzymology. 366: 321-338.  0.641
2002 Alirezaei M, Mordelet E, Rouach N, Nairn AC, Glowinski J, Prémont J. Zinc-induced inhibition of protein synthesis and reduction of connexin-43 expression and intercellular communication in mouse cortical astrocytes. The European Journal of Neuroscience. 16: 1037-44. PMID 12383232 DOI: 10.1046/j.1460-9568.2002.02180.x  0.384
2002 Gauchy C, Nairn AC, Glowinski J, Prémont J. N-Methyl-D-aspartate receptor activation inhibits protein synthesis in cortical neurons independently of its ionic permeability properties. Neuroscience. 114: 859-67. PMID 12379242 DOI: 10.1016/S0306-4522(02)00322-6  0.348
2002 Grossman SD, Hsieh-Wilson LC, Allen PB, Nairn AC, Greengard P. The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines. Neuromolecular Medicine. 2: 61-9. PMID 12230305 DOI: 10.1385/Nmm:2:1:61  0.672
2002 Liu F, Virshup DM, Nairn AC, Greengard P. Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors. The Journal of Biological Chemistry. 277: 45393-9. PMID 12223474 DOI: 10.1074/Jbc.M204499200  0.588
2002 Irwin N, Chao S, Goritchenko L, Horiuchi A, Greengard P, Nairn AC, Benowitz LI. Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19. Proceedings of the National Academy of Sciences of the United States of America. 99: 12427-31. PMID 12221279 DOI: 10.1073/Pnas.152457399  0.49
2002 Lindskog M, Svenningsson P, Pozzi L, Kim Y, Fienberg AA, Bibb JA, Fredholm BB, Nairn AC, Greengard P, Fisone G. Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine. Nature. 418: 774-8. PMID 12181566 DOI: 10.1038/Nature00817  0.761
2002 Feschenko MS, Stevenson E, Nairn AC, Sweadner KJ. A novel cAMP-stimulated pathway in protein phosphatase 2A activation. The Journal of Pharmacology and Experimental Therapeutics. 302: 111-8. PMID 12065707 DOI: 10.1124/jpet.302.1.111  0.526
2002 Nishi A, Bibb JA, Matsuyama S, Hamada M, Higashi H, Nairn AC, Greengard P. Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A. Journal of Neurochemistry. 81: 832-41. PMID 12065642 DOI: 10.1046/j.1471-4159.2002.00876.x  0.769
2002 Kranz JK, Lee EK, Nairn AC, Wand AJ. A direct test of the reductionist approach to structural studies of calmodulin activity: relevance of peptide models of target proteins. The Journal of Biological Chemistry. 277: 16351-4. PMID 11904288 DOI: 10.1074/jbc.C200139200  0.343
2002 Pastorino L, Ikin AF, Nairn AC, Pursnani A, Buxbaum JD. The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta). Molecular and Cellular Neurosciences. 19: 175-85. PMID 11860271 DOI: 10.1006/mcne.2001.1065  0.54
2001 Kim SH, Nairn AC, Cairns N, Lubec G. Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease. Journal of Neural Transmission. Supplementum. 263-72. PMID 11771749 DOI: 10.1007/978-3-7091-6262-0_21  0.378
2001 Nairn AC, Greengard P. A novel cyclin provides a link between dopamine and RNA processing. Neuron. 32: 174-6. PMID 11683987 DOI: 10.1016/S0896-6273(01)00469-X  0.451
2001 Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Greengard P, Czernik AJ. Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7944-53. PMID 11588168  0.763
2001 Liu F, Ma XH, Ule J, Bibb JA, Nishi A, DeMaggio AJ, Yan Z, Nairn AC, Greengard P. Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 98: 11062-8. PMID 11572969 DOI: 10.1073/Pnas.191353898  0.801
2001 Chen Y, Matsushita M, Nairn AC, Damuni Z, Cai D, Frerichs KU, Hallenbeck JM. Mechanisms for increased levels of phosphorylation of elongation factor-2 during hibernation in ground squirrels. Biochemistry. 40: 11565-70. PMID 11560506 DOI: 10.1021/bi010649w  0.429
2001 Althausen S, Mengesdorf T, Mies G, Oláh L, Nairn AC, Proud CG, Paschen W. Changes in the phosphorylation of initiation factor eIF-2alpha, elongation factor eEF-2 and p70 S6 kinase after transient focal cerebral ischaemia in mice. Journal of Neurochemistry. 78: 779-87. PMID 11520898 DOI: 10.1046/j.1471-4159.2001.00462.x  0.421
2001 Everett AD, Stoops TD, Nairn AC, Brautigan D. Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 281: H161-7. PMID 11406481 DOI: 10.1152/Ajpheart.2001.281.1.H161  0.431
2001 Yamaguchi H, Matsushita M, Nairn AC, Kuriyan J. Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Molecular Cell. 7: 1047-57. PMID 11389851 DOI: 10.1016/S1097-2765(01)00256-8  0.457
2001 Huang HB, Chen YC, Horiuchi A, Tsai LH, Liu HT, Chyan CL, Hsieh MJ, Liu CK, Lin FM, Greengard P, Nairn AC, Shiao MS, Lin TH. Backbone 1H, 15N, and 13C resonance assignments of ARPP-19. Journal of Biomolecular Nmr. 19: 383-4. PMID 11370788 DOI: 10.1023/A:1011214512601  0.366
2001 Kisielow J, Nairn AC, Karjalainen K. TARPP, a novel protein that accompanies TCR gene rearrangement and thymocyte education. European Journal of Immunology. 31: 1141-9. PMID 11298339 DOI: 10.1002/1521-4141(200104)31:4<1141::AID-IMMU1141>3.0.CO;2-R  0.326
2001 Dulubova I, Horiuchi A, Snyder GL, Girault JA, Czernik AJ, Shao L, Ramabhadran R, Greengard P, Nairn AC. ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins. Journal of Neurochemistry. 77: 229-38. PMID 11279279 DOI: 10.1046/j.1471-4159.2001.00191.x  0.711
2001 Bibb JA, Nishi A, O'Callaghan JP, Ule J, Lan M, Snyder GL, Horiuchi A, Saito T, Hisanaga S, Czernik AJ, Nairn AC, Greengard P. Phosphorylation of protein phosphatase inhibitor-1 by Cdk5. The Journal of Biological Chemistry. 276: 14490-7. PMID 11278334 DOI: 10.1074/jbc.M007197200  0.769
2001 Bibb JA, Chen J, Taylor JR, Svenningsson P, Nishi A, Snyder GL, Yan Z, Sagawa ZK, Ouimet CC, Nairn AC, Nestler EJ, Greengard P. Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature. 410: 376-80. PMID 11268215 DOI: 10.1038/35066591  0.796
2001 Watanabe T, Huang HB, Horiuchi A, da Cruze Silva EF, Hsieh-Wilson L, Allen PB, Shenolikar S, Greengard P, Nairn AC. Protein phosphatase 1 regulation by inhibitors and targeting subunits. Proceedings of the National Academy of Sciences of the United States of America. 98: 3080-5. PMID 11248035 DOI: 10.1073/Pnas.051003898  0.724
2001 Alirezaei M, Marin P, Nairn AC, Glowinski J, Prémont J. Inhibition of protein synthesis in cortical neurons during exposure to hydrogen peroxide. Journal of Neurochemistry. 76: 1080-8. PMID 11181828 DOI: 10.1046/j.1471-4159.2001.00105.x  0.345
2001 Lengyel I, Nairn AC, McCluskey A, Tóth G, Penke B, Rostas JAP. Auto-inhibition of Ca2+/calmodulin-dependent protein kinase II by its ATP-binding domain Journal of Neurochemistry. 76: 1066-1072. PMID 11181826 DOI: 10.1046/J.1471-4159.2001.00139.X  0.397
2001 Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Greengard P, Czernik AJ. Opposing Changes in Phosphorylation of Specific Sites in Synapsin I During Ca2+-Dependent Glutamate Release in Isolated Nerve Terminals The Journal of Neuroscience. 21: 7944-7953. DOI: 10.1523/Jneurosci.21-20-07944.2001  0.828
2000 Nishi A, Bibb JA, Snyder GL, Higashi H, Nairn AC, Greengard P. Amplification of dopaminergic signaling by a positive feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 97: 12840-5. PMID 11050161 DOI: 10.1073/pnas.220410397  0.746
2000 Huang HB, Chen YC, Tsai LH, Wang H, Lin FM, Horiuchi A, Greengard P, Nairn AC, Shiao MS, Lin TH. Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 -- a protein inhibitor of protein phosphatase-1. Journal of Biomolecular Nmr. 17: 359-60. PMID 11014604 DOI: 10.1023/A:1008355428294  0.491
2000 Iijima K, Ando K, Takeda S, Satoh Y, Seki T, Itohara S, Greengard P, Kirino Y, Nairn AC, Suzuki T. Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5. Journal of Neurochemistry. 75: 1085-91. PMID 10936190 DOI: 10.1046/J.1471-4159.2000.0751085.X  0.678
2000 Chan KW, Csanády L, Seto-Young D, Nairn AC, Gadsby DC. Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain. The Journal of General Physiology. 116: 163-80. PMID 10919864 DOI: 10.1085/Jgp.116.2.163  0.329
2000 Cho SI, Koketsu M, Ishihara H, Matsushita M, Nairn AC, Fukazawa H, Uehara Y. Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor-2 kinase. Biochimica Et Biophysica Acta. 1475: 207-15. PMID 10913818 DOI: 10.1016/S0304-4165(00)00061-1  0.466
2000 Paul S, Snyder GL, Yokakura H, Picciotto MR, Nairn AC, Lombroso PJ. The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5630-8. PMID 10908600 DOI: 10.1523/Jneurosci.20-15-05630.2000  0.81
2000 Caporaso GL, Bibb JA, Snyder GL, Valle C, Rakhilin S, Fienberg AA, Hemmings HC, Nairn AC, Greengard P. Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia. Neuropharmacology. 39: 1637-44. PMID 10854908 DOI: 10.1016/S0028-3908(99)00230-0  0.814
2000 Snyder GL, Allen PB, Fienberg AA, Valle CG, Huganir RL, Nairn AC, Greengard P. Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4480-8. PMID 10844017  0.597
2000 Bibb JA, Yan Z, Svenningsson P, Snyder GL, Pieribone VA, Horiuchi A, Nairn AC, Messer A, Greengard P. Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 6809-14. PMID 10829080 DOI: 10.1073/Pnas.120166397  0.792
2000 Connor JH, Frederick D, Huang Hb, Yang J, Helps NR, Cohen PT, Nairn AC, DePaoli-Roach A, Tatchell K, Shenolikar S. Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit. The Journal of Biological Chemistry. 275: 18670-5. PMID 10748125 DOI: 10.1074/Jbc.M909312199  0.355
2000 Zelenina M, Christensen BM, Palmér J, Nairn AC, Nielsen S, Aperia A. Prostaglandin E(2) interaction with AVP: effects on AQP2 phosphorylation and distribution. American Journal of Physiology. Renal Physiology. 278: F388-94. PMID 10710543 DOI: 10.1152/Ajprenal.2000.278.3.F388  0.405
2000 Scheetz AJ, Nairn AC, Constantine-Paton M. NMDA receptor-mediated control of protein synthesis at developing synapses. Nature Neuroscience. 3: 211-6. PMID 10700251 DOI: 10.1038/72915  0.458
2000 Aggen JB, Nairn AC, Chamberlin R. Regulation of protein phosphatase-1. Chemistry & Biology. 7: R13-23. PMID 10662690 DOI: 10.1016/S1074-5521(00)00069-7  0.465
2000 Snyder GL, Allen PB, Fienberg AA, Valle CG, Huganir RL, Nairn AC, Greengard P. Regulation of Phosphorylation of the GluR1 AMPA Receptor in the Neostriatum by Dopamine and Psychostimulants In Vivo The Journal of Neuroscience. 20: 4480-4488. DOI: 10.1523/JNEUROSCI.20-12-04480.2000  0.701
1999 Nishimoto G, Zelenina M, Li D, Yasui M, Aperia A, Nielsen S, Nairn AC. Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue. American Journal of Physiology. Renal Physiology. 276: F254-F259. PMID 29591637 DOI: 10.1152/ajprenal.1999.276.2.F254  0.335
1999 Tsumura T, Murata A, Yamaguchi F, Sugimoto K, Hasegawa E, Hatase O, Nairn AC, Tokuda M. The expression of Ca2+/calmodulin-dependent protein kinase I in rat retina is regulated by light stimulation. Vision Research. 39: 3165-73. PMID 10615488 DOI: 10.1016/S0042-6989(99)00063-2  0.606
1999 Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ, Huganir RL, Hemmings HC, Nairn AC, Greengard P. Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature. 402: 669-71. PMID 10604473 DOI: 10.1038/45251  0.857
1999 Lawson ND, Zain M, Zibello T, Picciotto MR, Nairn AC, Berliner N. Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturation. Experimental Hematology. 27: 1682-90. PMID 10560916 DOI: 10.1016/S0301-472X(99)00108-3  0.711
1999 Alirezaei M, Nairn AC, Glowinski J, Prémont J, Marin P. Zinc inhibits protein synthesis in neurons. Potential role of phosphorylation of translation initiation factor-2alpha. The Journal of Biological Chemistry. 274: 32433-8. PMID 10542287 DOI: 10.1074/jbc.274.45.32433  0.418
1999 McAvoy T, Allen PB, Obaishi H, Nakanishi H, Takai Y, Greengard P, Nairn AC, Hemmings HC. Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation. Biochemistry. 38: 12943-9. PMID 10504266 DOI: 10.1021/Bi991227D  0.715
1999 Nishi A, Fisone G, Snyder GL, Dulubova I, Aperia A, Nairn AC, Greengard P. Regulation of Na+, K+-ATPase isoforms in rat neostriatum by dopamine and protein kinase C. Journal of Neurochemistry. 73: 1492-501. PMID 10501194 DOI: 10.1046/J.1471-4159.1999.0731492.X  0.525
1999 Chung H, Nairn AC, Murata K, Brautigan DL. Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2. Biochemistry. 38: 10371-6. PMID 10441131 DOI: 10.1021/Bi990902G  0.384
1999 Maréchal E, Hiratsuka K, Delgado J, Nairn A, Qin J, Chait BT, Chua NH. Modulation of GT-1 DNA-binding activity by calcium-dependent phosphorylation. Plant Molecular Biology. 40: 373-86. PMID 10437822 DOI: 10.1023/A:1006131330930  0.39
1999 Greengard P, Allen PB, Nairn AC. Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade. Neuron. 23: 435-47. PMID 10433257 DOI: 10.1016/S0896-6273(00)80798-9  0.464
1999 Nishi A, Snyder GL, Fienberg AA, Fisone G, Aperia A, Nairn AC, Greengard P. Requirement for DARPP-32 in mediating effect of dopamine D2 receptor activation. The European Journal of Neuroscience. 11: 2589-92. PMID 10383649 DOI: 10.1046/J.1460-9568.1999.00724.X  0.476
1999 Cheng SX, Aizman O, Nairn AC, Greengard P, Aperia A. [Ca2+]i determines the effects of protein kinases A and C on activity of rat renal Na+,K+-ATPase. The Journal of Physiology. 518: 37-46. PMID 10373687 DOI: 10.1111/J.1469-7793.1999.0037R.X  0.496
1999 Ando K, Oishi M, Takeda S, Iijima K, Isohara T, Nairn AC, Kirino Y, Greengard P, Suzuki T. Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4421-7. PMID 10341243  0.308
1999 Isohara T, Horiuchi A, Watanabe T, Ando K, Czernik AJ, Uno I, Greengard P, Nairn AC, Suzuki T. Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase. Biochemical and Biophysical Research Communications. 258: 300-5. PMID 10329382 DOI: 10.1006/Bbrc.1999.0637  0.716
1999 Fienberg AA, Nordstedt C, Belting HG, Czernik AJ, Nairn AC, Gandy S, Greengard P, Ruddle FH. Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6. The Journal of Experimental Zoology. 285: 76-84. PMID 10327653 DOI: 10.1002/(SICI)1097-010X(19990415)285:1<76::AID-JEZ9>3.0.CO;2-K  0.605
1999 Aggen JB, Humphrey JM, Gauss CM, Huang HB, Nairn AC, Chamberlin AR. The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity. Bioorganic & Medicinal Chemistry. 7: 543-64. PMID 10220039 DOI: 10.1016/S0968-0896(98)00254-5  0.323
1999 Nishi A, Snyder GL, Nairn AC, Greengard P. Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons. Journal of Neurochemistry. 72: 2015-21. PMID 10217279 DOI: 10.1046/j.1471-4159.1999.0722015.x  0.597
1999 Yan Z, Hsieh-Wilson L, Feng J, Tomizawa K, Allen PB, Fienberg AA, Nairn AC, Greengard P. Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin. Nature Neuroscience. 2: 13-7. PMID 10195174 DOI: 10.1038/4516  0.788
1999 Hsieh-Wilson LC, Allen PB, Watanabe T, Nairn AC, Greengard P. Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1. Biochemistry. 38: 4365-73. PMID 10194355 DOI: 10.1021/Bi982900M  0.708
1999 Matsushita M, Nairn AC. Inhibition of the Ca2+/calmodulin-dependent protein kinase I cascade by cAMP-dependent protein kinase. The Journal of Biological Chemistry. 274: 10086-93. PMID 10187789 DOI: 10.1074/jbc.274.15.10086  0.525
1999 Huang HB, Horiuchi A, Watanabe T, Shih SR, Tsay HJ, Li HC, Greengard P, Nairn AC. Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2. The Journal of Biological Chemistry. 274: 7870-8. PMID 10075680 DOI: 10.1074/jbc.274.12.7870  0.506
1999 Endo S, Suzuki M, Sumi M, Nairn AC, Morita R, Yamakawa K, Greengard P, Ito M. Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 2467-72. PMID 10051666 DOI: 10.1073/pnas.96.5.2467  0.545
1999 Nishimoto G, Zelenina M, Li D, Yasui M, Aperia A, Nielsen S, Nairn AC. Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue. The American Journal of Physiology. 276: F254-9. PMID 9950956 DOI: 10.1152/Ajprenal.1999.276.2.F254  0.447
1999 Watanabe T, Sukegawa J, Sukegawa I, Tomita S, Iijima K, Oguchi S, Suzuki T, Nairn AC, Greengard P. A 127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein. Journal of Neurochemistry. 72: 549-56. PMID 9930726 DOI: 10.1046/J.1471-4159.1999.0720549.X  0.62
1999 Gadsby DC, Nairn AC. Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis. Physiological Reviews. 79: S77-S107. PMID 9922377 DOI: 10.1152/Physrev.1999.79.1.S77  0.335
1999 Ando K, Oishi M, Takeda S, Iijima K, Isohara T, Nairn AC, Kirino Y, Greengard P, Suzuki T. Role of Phosphorylation of Alzheimer’s Amyloid Precursor Protein during Neuronal Differentiation The Journal of Neuroscience. 19: 4421-4427. DOI: 10.1523/Jneurosci.19-11-04421.1999  0.662
1999 Everett AD, Nairn A, Cho H, Stoops TD. Angiotensin II Regulates Cardiac Myocyte Protein Synthesis by Activation of Elongation Factor 2 Pediatric Research. 45: 22A-22A. DOI: 10.1203/00006450-199904020-00138  0.316
1999 Cheng SXJ, Aizman O, Nairn AC, Greengard P, Aperia A. [Ca2+](i) determines the effects of protein kinases A and C on activity of rat renal Na+,K+-ATPase Journal of Physiology. 518: 37-46. DOI: 10.1111/j.1469-7793.1999.0037r.x  0.419
1998 Pereda AE, Bell TD, Chang BH, Czernik AJ, Nairn AC, Soderling TR, Faber DS. Ca2+/calmodulin-dependent kinase II mediates simultaneous enhancement of gap-junctional conductance and glutamatergic transmission. Proceedings of the National Academy of Sciences of the United States of America. 95: 13272-7. PMID 9789078 DOI: 10.1073/pnas.95.22.13272  0.347
1998 Matsushita M, Nairn AC. Characterization of the mechanism of regulation of Ca2+/ calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinase. The Journal of Biological Chemistry. 273: 21473-81. PMID 9705275 DOI: 10.1074/jbc.273.34.21473  0.471
1998 Greengard P, Nairn AC, Girault JA, Ouimet CC, Snyder GL, Fisone G, Allen PB, Fienberg A, Nishi A. The DARPP-32/protein phosphatase-1 cascade: a model for signal integration. Brain Research. Brain Research Reviews. 26: 274-84. PMID 9651542 DOI: 10.1016/S0165-0173(97)00057-X  0.746
1998 Matovcik LM, Nairn AC, Gorelick FS. Cellular localization of calmodulin-dependent protein kinases I and II to A-cells and D-cells of the endocrine pancreas. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 46: 519-26. PMID 9524198 DOI: 10.1177/002215549804600412  0.465
1998 Wang F, Zeltwanger S, Yang IC, Nairn AC, Hwang TC. Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating. Evidence for two binding sites with opposite effects. The Journal of General Physiology. 111: 477-90. PMID 9482713 DOI: 10.1085/jgp.111.3.477  0.396
1998 Allen PB, Kwon YG, Nairn AC, Greengard P. Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit. The Journal of Biological Chemistry. 273: 4089-95. PMID 9461602 DOI: 10.1074/jbc.273.7.4089  0.532
1998 Desdouits F, Siciliano JC, Nairn AC, Greengard P, Girault JA. Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons. The Biochemical Journal. 330: 211-6. PMID 9461512 DOI: 10.1042/BJ3300211  0.701
1998 Desdouits-Magnen J, Desdouits F, Takeda S, Syu LJ, Saltiel AR, Buxbaum JD, Czernik AJ, Nairn AC, Greengard P. Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade. Journal of Neurochemistry. 70: 524-30. PMID 9453546 DOI: 10.1046/J.1471-4159.1998.70020524.X  0.676
1998 Matsushita M, Moriwaki A, Kondo E, Matsui H, Nairn AC. Structure and regulation of Ca2+/calmodulin dependent protein kinase III (elongation factor 2 kinase) Neuroscience Research. 31. DOI: 10.1016/S0168-0102(98)82003-8  0.466
1998 Matsnshita M, Nairn AC. Structure and regulation of elongation factor 2 kinase (EF2K) Faseb Journal. 12.  0.335
1998 McAvov T, Nairn AC, Greengard P, Hemmings HC. Identification and purification of protein phosphatase 1 binding proteins in rat brain Faseb Journal. 12: A1300.  0.527
1997 Cheng XJ, Höög JO, Nairn AC, Greengard P, Aperia A. Regulation of rat Na-K-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA. American Journal of Physiology. Cell Physiology. 273: C1981-C1986. PMID 29585085 DOI: 10.1152/ajpcell.1997.273.6.C1981  0.486
1997 Cheng XJ, Höög JO, Nairn AC, Greengard P, Aperia A. Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA. The American Journal of Physiology. 273: C1981-6. PMID 9435504 DOI: 10.1152/Ajpcell.1997.273.6.C1981  0.42
1997 Scheetz AJ, Nairn AC, Constantine-Paton M. N-methyl-D-aspartate receptor activation and visual activity induce elongation factor-2 phosphorylation in amphibian tecta: a role for N-methyl-D-aspartate receptors in controlling protein synthesis. Proceedings of the National Academy of Sciences of the United States of America. 94: 14770-5. PMID 9405688 DOI: 10.1073/Pnas.94.26.14770  0.454
1997 Gauss CM, Sheppeck JE, Nairn AC, Chamberlin R. A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the Ser-Thr phosphatases, PP1 and PP2A. Bioorganic & Medicinal Chemistry. 5: 1751-73. PMID 9354231 DOI: 10.1016/S0968-0896(97)00145-4  0.416
1997 Sáez JC, Nairn AC, Czernik AJ, Fishman GI, Spray DC, Hertzberg EL. Phosphorylation of connexin43 and the regulation of neonatal rat cardiac myocyte gap junctions. Journal of Molecular and Cellular Cardiology. 29: 2131-45. PMID 9281445 DOI: 10.1006/Jmcc.1997.0447  0.448
1997 Belusa R, Wang ZM, Matsubara T, Sahlgren B, Dulubova I, Nairn AC, Ruoslahti E, Greengard P, Aperia A. Mutation of the protein kinase C phosphorylation site on rat alpha1 Na+,K+-ATPase alters regulation of intracellular Na+ and pH and influences cell shape and adhesiveness. The Journal of Biological Chemistry. 272: 20179-84. PMID 9242694 DOI: 10.1074/jbc.272.32.20179  0.487
1997 Blackshear PJ, Silver J, Nairn AC, Sulik KK, Squier MV, Stumpo DJ, Tuttle JS. Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice. Experimental Neurology. 145: 46-61. PMID 9184108 DOI: 10.1006/Exnr.1997.6475  0.339
1997 Marin P, Nastiuk KL, Daniel N, Girault JA, Czernik AJ, Glowinski J, Nairn AC, Prémont J. Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3445-54. PMID 9133370 DOI: 10.1523/Jneurosci.17-10-03445.1997  0.797
1997 Kwon YG, Lee SY, Choi Y, Greengard P, Nairn AC. Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 2168-73. PMID 9122166 DOI: 10.1073/Pnas.94.6.2168  0.59
1997 Suzuki T, Ando K, Isohara T, Oishi M, Lim GS, Satoh Y, Wasco W, Tanzi RE, Nairn AC, Greengard P, Gandy SE, Kirino Y. Phosphorylation of Alzheimer beta-amyloid precursor-like proteins. Biochemistry. 36: 4643-9. PMID 9109675 DOI: 10.1021/Bi962618K  0.672
1997 Kwon YG, Huang HB, Desdouits F, Girault JA, Greengard P, Nairn AC. Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 94: 3536-41. PMID 9108011 DOI: 10.1073/PNAS.94.8.3536  0.648
1997 Huang HB, Horiuchi A, Goldberg J, Greengard P, Nairn AC. Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding. Proceedings of the National Academy of Sciences of the United States of America. 94: 3530-5. PMID 9108010 DOI: 10.1073/pnas.94.8.3530  0.467
1997 Nowicki S, Chen SL, Aizman O, Cheng XJ, Li D, Nowicki C, Nairn A, Greengard P, Aperia A. 20-Hydroxyeicosa-tetraenoic acid (20 HETE) activates protein kinase C. Role in regulation of rat renal Na+,K+-ATPase. The Journal of Clinical Investigation. 99: 1224-30. PMID 9077530 DOI: 10.1172/JCI119279  0.494
1997 Nevalainen LT, Aoyama T, Ikura M, Crivici A, Yan H, Chua NH, Nairn AC. Characterization of novel calmodulin-binding peptides with distinct inhibitory effects on calmodulin-dependent enzymes. The Biochemical Journal. 321: 107-15. PMID 9003408 DOI: 10.1042/Bj3210107  0.363
1997 Oishi M, Nairn AC, Czernik AJ, Lim GS, Isohara T, Gandy SE, Greengard P, Suzuki T. The Cytoplasmic Domain of Alzheimer’s Amyloid Precursor Protein Is Phosphorylated at Thr654, Ser655, and Thr668 in Adult Rat Brain and Cultured Cells Molecular Medicine. 3: 111-123. DOI: 10.1007/Bf03401803  0.692
1996 Blackshear PJ, Lai WS, Tuttle JS, Stumpo DJ, Kennington E, Nairn AC, Sulik KK. Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency. Brain Research. Developmental Brain Research. 96: 62-75. PMID 8922669 DOI: 10.1016/0165-3806(96)00097-1  0.436
1996 Marino MW, Dunbar JD, Wu LW, Ngaiza JR, Han HM, Guo D, Matsushita M, Nairn AC, Zhang Y, Kolesnick R, Jaffe EA, Donner DB. Inhibition of tumor necrosis factor signal transduction in endothelial cells by dimethylaminopurine. The Journal of Biological Chemistry. 271: 28624-9. PMID 8910494 DOI: 10.1074/Jbc.271.45.28624  0.431
1996 Logvinenko NS, Dulubova I, Fedosova N, Larsson SH, Nairn AC, Esmann M, Greengard P, Aperia A. Phosphorylation by protein kinase C of serine-23 of the alpha-1 subunit of rat Na+,K(+)-ATPase affects its conformational equilibrium. Proceedings of the National Academy of Sciences of the United States of America. 93: 9132-7. PMID 8799166 DOI: 10.1073/PNAS.93.17.9132  0.568
1996 Desdouits F, Buxbaum JD, Desdouits-Magnen J, Nairn AC, Greengard P. Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin. The Journal of Biological Chemistry. 271: 24670-4. PMID 8798734 DOI: 10.1074/jbc.271.40.24670  0.616
1996 Picciotto MR, Nastiuk KL, Nairn AC. Structure, regulation, and function of calcium/calmodulin-dependent protein kinase I. Advances in Pharmacology (San Diego, Calif.). 36: 251-75. PMID 8783563 DOI: 10.1016/S1054-3589(08)60585-2  0.84
1996 Aletta JM, Selbert MA, Nairn AC, Edelman AM. Activation of a calcium-calmodulin-dependent protein kinase I cascade in PC12 cells. The Journal of Biological Chemistry. 271: 20930-4. PMID 8702851 DOI: 10.1074/Jbc.271.34.20930  0.475
1996 Goldberg J, Nairn AC, Kuriyan J. Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I. Cell. 84: 875-87. PMID 8601311 DOI: 10.1016/S0092-8674(00)81066-1  0.387
1996 Qian Y, Chao DS, Santillano DR, Cornwell TL, Nairn AC, Greengard P, Lincoln TM, Bredt DS. cGMP-Dependent Protein Kinase in Dorsal Root Ganglion: Relationship with Nitric Oxide Synthase and Nociceptive Neurons The Journal of Neuroscience. 16: 3130-3138. DOI: 10.1523/Jneurosci.16-10-03130.1996  0.49
1996 Nairn AC, Palfrey HC. 10 Regulation of Protein Synthesis by Calcium Cold Spring Harbor Monograph Archive. 30: 295-318. DOI: 10.1101/087969458.30.295  0.46
1996 Watanabe T, Suzuki T, Sukegawa J, Sukegawa I, Nairn A, Greengard P. 387 Identification of a protein which interacts with the cytoplasmic domain of the Alzheimer amyloid protein Precursor Neurobiology of Aging. 17: S97. DOI: 10.1016/S0197-4580(96)80389-7  0.611
1995 Desdouits F, Cheetham JJ, Huang HB, Kwon YG, da Cruz e Silva EF, Denefle P, Ehrlich ME, Nairn AC, Greengard P, Girault JA. Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides. Biochemical and Biophysical Research Communications. 206: 652-8. PMID 7826384 DOI: 10.1006/bbrc.1995.1092  0.825
1995 Desdouits F, Cohen D, Nairn AC, Greengard P, Girault JA. Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo. The Journal of Biological Chemistry. 270: 8772-8. PMID 7721783 DOI: 10.1074/jbc.270.15.8772  0.738
1995 Goldberg J, Huang HB, Kwon YG, Greengard P, Nairn AC, Kuriyan J. Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1. Nature. 376: 745-53. PMID 7651533 DOI: 10.1038/376745A0  0.494
1995 Picciotto MR, Zoli M, Bertuzzi G, Nairn AC. Immunochemical localization of calcium/calmodulin-dependent protein kinase I. Synapse (New York, N.Y.). 20: 75-84. PMID 7624832 DOI: 10.1002/syn.890200111  0.707
1995 French PJ, Bijman J, Edixhoven M, Vaandrager AB, Scholte BJ, Lohmann SM, Nairn AC, de Jonge HR. Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II. The Journal of Biological Chemistry. 270: 26626-31. PMID 7592887 DOI: 10.1074/Jbc.270.44.26626  0.418
1995 Yokokura H, Picciotto MR, Nairn AC, Hidaka H. The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domains. The Journal of Biological Chemistry. 270: 23851-9. PMID 7559563 DOI: 10.1074/jbc.270.40.23851  0.71
1995 Sihra TS, Nairn AC, Kloppenburg P, Lin Z, Pouzat C. A role for calcineurin (protein phosphatase-2B) in the regulation of glutamate release. Biochemical and Biophysical Research Communications. 212: 609-16. PMID 7542882 DOI: 10.1006/bbrc.1995.2013  0.64
1995 Hincke MT, Nairn AC, Staines WA. Cystic fibrosis transmembrane conductance regulator is found within brain ventricular epithelium and choroid plexus. Journal of Neurochemistry. 64: 1662-8. PMID 7534334 DOI: 10.1046/J.1471-4159.1995.64041662.X  0.331
1995 Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P. Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons. Neuron. 14: 385-97. PMID 7531987 DOI: 10.1016/0896-6273(95)90294-5  0.693
1994 Pereda AE, Nairn AC, Wolszon LR, Faber DS. Postsynaptic modulation of synaptic efficacy at mixed synapses on the Mauthner cell. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3704-12. PMID 8207483 DOI: 10.1523/Jneurosci.14-06-03704.1994  0.396
1994 Hvalby O, Hemmings HC, Paulsen O, Czernik AJ, Nairn AC, Godfraind JM, Jensen V, Raastad M, Storm JF, Andersen P. Specificity of protein kinase inhibitor peptides and induction of long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America. 91: 4761-5. PMID 8197132 DOI: 10.1073/Pnas.91.11.4761  0.606
1994 Suzuki T, Oishi M, Marshak DR, Czernik AJ, Nairn AC, Greengard P. Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein. The Embo Journal. 13: 1114-22. PMID 8131745  0.343
1994 Hyatt SL, Liao L, Aderem A, Nairn AC, Jaken S. Correlation between protein kinase C binding proteins and substrates in REF52 cells. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 5: 495-502. PMID 8049156  0.33
1994 Ito T, Yokokura H, Nairn AC, Nimura Y, Hidaka H. Ca2+/calmodulin-dependent protein kinase V and I may form a family of isoforms. Biochemical and Biophysical Research Communications. 201: 1561-6. PMID 8024601 DOI: 10.1006/bbrc.1994.1882  0.468
1994 Dohadwala M, da Cruz e Silva EF, Hall FL, Williams RT, Carbonaro-Hall DA, Nairn AC, Greengard P, Berndt N. Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases. Proceedings of the National Academy of Sciences of the United States of America. 91: 6408-12. PMID 8022797 DOI: 10.1073/Pnas.91.14.6408  0.777
1994 Terada N, Patel HR, Takase K, Kohno K, Nairn AC, Gelfand EW. Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 11477-81. PMID 7972087 DOI: 10.1073/Pnas.91.24.11477  0.41
1994 Nairn AC, Picciotto MR. Calcium/calmodulin-dependent protein kinases. Seminars in Cancer Biology. 5: 295-303. PMID 7803766  0.717
1994 Gadsby DC, Nairn AC. Regulation of CFTR channel gating. Trends in Biochemical Sciences. 19: 513-8. PMID 7531880 DOI: 10.1016/0968-0004(94)90141-4  0.328
1994 Hwang TC, Nagel G, Nairn AC, Gadsby DC. Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 91: 4698-702. PMID 7515176 DOI: 10.1073/Pnas.91.11.4698  0.359
1994 Fisone G, Cheng SX, Nairn AC, Czernik AJ, Hemmings HC, Höög JO, Bertorello AM, Kaiser R, Bergman T, Jörnvall H. Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis. The Journal of Biological Chemistry. 269: 9368-73. PMID 7510709  0.581
1994 Nairn A. Structure and function of calcium/calmodulin-dependent protein kinases Pathophysiology. 1: 73. DOI: 10.1016/0928-4680(94)90170-8  0.304
1994 Oishi M, Lim GS, Isohara T, Watanabe T, Qu Z, Horiuchi A, Marshak DR, Czernik AJ, Nairn AC, Greengard P, Suzuki T. Regulated Phosphorylation of App in-Vivo Neurobiology of Aging. 15. DOI: 10.1016/0197-4580(94)92796-0  0.612
1994 Suzuki T, Oishi M, Marshak D, Czernik A, Nairn A, Greengard P. Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein. The Embo Journal. 13: 1114-1122. DOI: 10.1002/J.1460-2075.1994.Tb06360.X  0.674
1993 Gadsby DC, Hwang TC, Horie M, Nagel G, Nairn AC. Cardiac chloride channels: incremental regulation by phosphorylation/dephosphorylation. Annals of the New York Academy of Sciences. 707: 259-74. PMID 9137557 DOI: 10.1111/J.1749-6632.1993.Tb38057.X  0.341
1993 Mitsui K, Brady M, Palfrey HC, Nairn AC. Purification and characterization of calmodulin-dependent protein kinase III from rabbit reticulocytes and rat pancreas. The Journal of Biological Chemistry. 268: 13422-33. PMID 8514778  0.391
1993 Bagaglio DM, Cheng EH, Gorelick FS, Mitsui K, Nairn AC, Hait WN. Phosphorylation of elongation factor 2 in normal and malignant rat glial cells. Cancer Research. 53: 2260-4. PMID 8485712  0.375
1993 Picciotto MR, Czernik AJ, Nairn AC. Calcium/calmodulin-dependent protein kinase I. cDNA cloning and identification of autophosphorylation site. The Journal of Biological Chemistry. 268: 26512-21. PMID 8253780  0.727
1993 Gandy SE, Caporaso GL, Buxbaum JD, de Cruz Silva O, Iverfeldt K, Nordstedt C, Suzuki T, Czernik AJ, Nairn AC, Greengard P. Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein. Annals of the New York Academy of Sciences. 695: 117-21. PMID 8239268 DOI: 10.1111/j.1749-6632.1993.tb23038.x  0.7
1993 Cohn JA, Strong TV, Picciotto MR, Nairn AC, Collins FS, Fitz JG. Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells. Gastroenterology. 105: 1857-64. PMID 7504645 DOI: 10.1016/0016-5085(93)91085-V  0.6
1992 Suzuki T, Nairn AC, Gandy SE, Greengard P. Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C. Neuroscience. 48: 755-61. PMID 1630623 DOI: 10.1016/0306-4522(92)90264-3  0.656
1992 Hartwig JH, Thelen M, Rosen A, Janmey PA, Nairn AC, Aderem A. MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin. Nature. 356: 618-22. PMID 1560845 DOI: 10.1038/356618A0  0.474
1992 Gandy SE, Buxbaum JD, Suzuki T, Ramabhadran TV, Caporaso GL, Nairn AC, Greengard P. The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notes. Neurobiology of Aging. 13: 601-3. PMID 1461349 DOI: 10.1016/0197-4580(92)90063-4  0.713
1992 Nairn AC, Aderem A. Calmodulin and protein kinase C cross-talk: the MARCKS protein is an actin filament and plasma membrane cross-linking protein regulated by protein kinase C phosphorylation and by calmodulin. Ciba Foundation Symposium. 164: 145-54; discussion 1. PMID 1395931  0.321
1992 Picciotto MR, Cohn JA, Bertuzzi G, Greengard P, Nairn AC. Phosphorylation of the cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 267: 12742-52. PMID 1377674  0.714
1992 Hwang TC, Horie M, Nairn AC, Gadsby DC. Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance. The Journal of General Physiology. 99: 465-89. PMID 1375958 DOI: 10.1085/Jgp.99.4.465  0.389
1992 Hincke MT, Nairn AC. Phosphorylation of elongation factor 2 during Ca(2+)-mediated secretion from rat parotid acini. The Biochemical Journal. 282: 877-82. PMID 1372803 DOI: 10.1042/Bj2820877  0.439
1992 Cohn JA, Nairn AC, Marino CR, Melhus O, Kole J. Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line. Proceedings of the National Academy of Sciences of the United States of America. 89: 2340-4. PMID 1372442 DOI: 10.1073/Pnas.89.6.2340  0.411
1992 Gandy SE, Caporaso GL, Ramabhadran TV, Suzuki T, Buxbaum JD, Nordstedt C, Iverfeldt K, Czernik AJ, Nairn AC, Greengard P. Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine. Annals of the New York Academy of Sciences. 674: 203-17. PMID 1363189 DOI: 10.1111/J.1749-6632.1992.Tb27489.X  0.652
1992 Hemmings HC, Girault JA, Nairn AC, Bertuzzi G, Greengard P. Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32. Journal of Neurochemistry. 59: 1053-61. PMID 1353788 DOI: 10.1111/j.1471-4159.1992.tb08347.x  0.691
1992 Johnson G, Gotlib J, Haroutunian V, Bierer L, Nairn AC, Merril C, Wallace W. Increased phosphorylation of elongation factor 2 in Alzheimer's disease. Brain Research. Molecular Brain Research. 15: 319-26. PMID 1331687 DOI: 10.1016/0169-328X(92)90124-T  0.434
1992 Nairn AC, Shenolikar S. The role of protein phosphatases in synaptic transmission, plasticity and neuronal development. Current Opinion in Neurobiology. 2: 296-301. PMID 1322750 DOI: 10.1016/0959-4388(92)90118-5  0.411
1992 Lin M, Nairn AC, Guggino SE. cGMP-dependent protein kinase regulation of a chloride channel in T84 cells. The American Journal of Physiology. 262: C1304-12. PMID 1317106 DOI: 10.1152/Ajpcell.1992.262.5.C1304  0.349
1992 Countaway JL, Nairn AC, Davis RJ. Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase. The Journal of Biological Chemistry. 267: 1129-40. PMID 1309762  0.367
1992 Nagel G, Hwang TC, Nastiuk KL, Nairn AC, Gadsby DC. The protein kinase A-regulated cardiac Cl- channel resembles the cystic fibrosis transmembrane conductance regulator. Nature. 360: 81-4. PMID 1279437 DOI: 10.1038/360081A0  0.712
1991 Thelen M, Rosen A, Nairn AC, Aderem A. Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane Nature. 351: 320-322. PMID 2034276 DOI: 10.1038/351320A0  0.429
1991 Gustafson EL, Girault JA, Hemmings HC, Nairn AC, Greengard P. Immunocytochemical localization of phosphatase inhibitor-1 in rat brain. The Journal of Comparative Neurology. 310: 170-88. PMID 1955581 DOI: 10.1002/cne.903100204  0.73
1991 Czernik AJ, Girault JA, Nairn AC, Chen J, Snyder G, Kebabian J, Greengard P. Production of phosphorylation state-specific antibodies. Methods in Enzymology. 201: 264-83. PMID 1943769 DOI: 10.1016/0076-6879(91)01025-W  0.556
1991 Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P. Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 2798-801. PMID 1849276 DOI: 10.1073/pnas.88.7.2798  0.664
1991 Marshall J, Martin KA, Picciotto M, Hockfield S, Nairn AC, Kaczmarek LK. Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 266: 22749-54. PMID 1718999  0.306
1991 Greengard P, Jen J, Nairn AC, Stevens CF. Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons. Science (New York, N.Y.). 253: 1135-8. PMID 1716001 DOI: 10.1126/science.1716001  0.503
1991 Bertorello AM, Aperia A, Walaas SI, Nairn AC, Greengard P. Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme. Proceedings of the National Academy of Sciences of the United States of America. 88: 11359-62. PMID 1662394 DOI: 10.1073/PNAS.88.24.11359  0.725
1991 Neumann J, Gupta RC, Schmitz W, Scholz H, Nairn AC, Watanabe AM. Evidence for isoproterenol-induced phosphorylation of phosphatase inhibitor-1 in the intact heart. Circulation Research. 69: 1450-7. PMID 1659500 DOI: 10.1161/01.Res.69.6.1450  0.412
1991 Graff JM, Rajan RR, Randall RR, Nairn AC, Blackshear PJ. Protein kinase C substrate and inhibitor characteristics of peptides derived from the myristoylated alanine-rich C kinase substrate (MARCKS) protein phosphorylation site domain. The Journal of Biological Chemistry. 266: 14390-8. PMID 1650359  0.39
1990 Rosen A, Keenan KF, Thelen M, Nairn AC, Aderem A. Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia Journal of Experimental Medicine. 172: 1211-1215. PMID 2212950 DOI: 10.1084/Jem.172.4.1211  0.471
1990 Hemmings HC, Nairn AC, Elliott JI, Greengard P. Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity. The Journal of Biological Chemistry. 265: 20369-76. PMID 2173704  0.637
1990 Sáez JC, Nairn AC, Czernik AJ, Spray DC, Hertzberg EL, Greengard P, Bennett MV. Phosphorylation of connexin 32, a hepatocyte gap-junction protein, by cAMP-dependent protein kinase, protein kinase C and Ca2+/calmodulin-dependent protein kinase II. European Journal of Biochemistry / Febs. 192: 263-73. PMID 2170122 DOI: 10.1111/J.1432-1033.1990.Tb19223.X  0.597
1990 Nichols RA, Sihra TS, Czernik AJ, Nairn AC, Greengard P. Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes. Nature. 343: 647-51. PMID 2154695 DOI: 10.1038/343647A0  0.768
1990 Thelen M, Rosen A, Nairn AC, Aderem A. Tumor necrosis factor α modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate Proceedings of the National Academy of Sciences of the United States of America. 87: 5603-5607. PMID 2116001 DOI: 10.1073/Pnas.87.15.5603  0.462
1990 Nairn AC. Role of Ca2+/calmodulin-dependent protein phosphorylation in signal transduction Advances in Second Messenger and Phosphoprotein Research. 24: 202-205. PMID 1976329  0.309
1990 Brady MJ, Nairn AC, Wagner JA, Palfrey HC. Nerve growth factor-induced down-regulation of calmodulin-dependent protein kinase III in PC12 cells involves cyclic AMP-dependent protein kinase Journal of Neurochemistry. 54: 1034-1039. PMID 1689374 DOI: 10.1111/J.1471-4159.1990.Tb02354.X  0.422
1989 Meister B, Fryckstedt J, Schalling M, Cortés R, Hökfelt T, Aperia A, Hemmings HC, Nairn AC, Ehrlich M, Greengard P. Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 8068-72. PMID 2573060 DOI: 10.1073/PNAS.86.20.8068  0.655
1989 Walaas SI, Nairn AC. Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms. Journal of Molecular Neuroscience : Mn. 1: 117-27. PMID 2561875 DOI: 10.1007/BF02918897  0.698
1989 Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P. Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II. The Journal of Biological Chemistry. 264: 21748-59. PMID 2557337  0.736
1989 Piomelli D, Wang JK, Sihra TS, Nairn AC, Czernik AJ, Greengard P. Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites. Proceedings of the National Academy of Sciences of the United States of America. 86: 8550-4. PMID 2554319 DOI: 10.1073/PNAS.86.21.8550  0.795
1989 Mackie K, Sorkin BC, Nairn AC, Greengard P, Edelman GM, Cunningham BA. Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 1883-96. PMID 2542481  0.396
1989 Conn PJ, Strong JA, Azhderian EM, Nairn AC, Greengard P, Kaczmarek LK. Protein kinase inhibitors selectively block phorbol ester- or forskolin-induced changes in excitability of Aplysia neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 473-9. PMID 2537389 DOI: 10.1523/Jneurosci.09-02-00473.1989  0.425
1989 Mackie KP, Nairn AC, Hampel G, Lam G, Jaffe EA. Thrombin and histamine stimulate the phosphorylation of elongation factor 2 in human umbilical vein endothelial cells. The Journal of Biological Chemistry. 264: 1748-53. PMID 2536373  0.585
1989 Hemmings HC, Nairn AC, McGuinness TL, Huganir RL, Greengard P. Role of protein phosphorylation in neuronal signal transduction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 3: 1583-92. PMID 2493406 DOI: 10.1096/fasebj.3.5.2493406  0.789
1989 Bahinski A, Nairn AC, Greengard P, Gadsby DC. Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes Nature. 340: 718-721. PMID 2475783 DOI: 10.1038/340718A0  0.517
1989 Li M, McCann JD, Anderson MP, Clancy JP, Liedtke CM, Nairn AC, Greengard P, Welsch MJ. Regulation of chloride channels by protein kinase C in normal and cystic fibrosis airway epithelia. Science (New York, N.Y.). 244: 1353-6. PMID 2472006 DOI: 10.1126/Science.2472006  0.505
1989 Mackie K, Sorkin B, Nairn A, Greengard P, Edelman G, Cunningham B. Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM The Journal of Neuroscience. 9: 1883-1896. DOI: 10.1523/Jneurosci.09-06-01883.1989  0.702
1989 Conn P, Strong J, Azhderian E, Nairn A, Greengard P, Kaczmarek L. Protein kinase inhibitors selectively block phorbol ester- or forskolin- induced changes in excitability of Aplysia neurons The Journal of Neuroscience. 9: 473-479. DOI: 10.1523/JNEUROSCI.09-02-00473.1989  0.497
1988 Walaas SI, Horn RS, Nairn AC, Walaas O, Adler A. Skeletal muscle sarcolemma proteins as targets for adenosine 3':5'-monophosphate-dependent and calcium-dependent protein kinases. Archives of Biochemistry and Biophysics. 262: 245-58. PMID 3355169 DOI: 10.1016/0003-9861(88)90186-5  0.698
1988 Nairn AC, Hemmings HC, Walaas SI, Greengard P. DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons. Journal of Neurochemistry. 50: 257-62. PMID 3335843 DOI: 10.1111/j.1471-4159.1988.tb13258.x  0.769
1988 Blackshear PJ, Nairn AC, Kuo JF. Protein kinases 1988: a current perspective. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 2957-69. PMID 2972578 DOI: 10.1096/Fasebj.2.14.2972578  0.665
1988 Weeks G, Picciotto M, Nairn AC, Walaas SI, Greengard P. Purification and characterization of PCPP-260: a Purkinje cell-enriched cyclic AMP-regulated membrane phosphoprotein of Mr 260,000. Synapse (New York, N.Y.). 2: 89-96. PMID 2844000 DOI: 10.1002/syn.890020112  0.801
1988 Thiel G, Czernik AJ, Gorelick F, Nairn AC, Greengard P. Ca2+/calmodulin-dependent protein kinase II: Identification of threonine-286 as the autophosphorylation site in the α subunit associated with the generation of Ca2+-independent activity Proceedings of the National Academy of Sciences of the United States of America. 85: 6337-6341. PMID 2842767 DOI: 10.1073/Pnas.85.17.6337  0.504
1988 Li M, McCann JD, Liedtke CM, Nairn AC, Greengard P, Welsh MJ. Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium. Nature. 331: 358-60. PMID 2448645 DOI: 10.1038/331358A0  0.481
1987 Nairn AC, Palfrey HC. Identification of the major M(r) 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2 Journal of Biological Chemistry. 262: 17299-17303. PMID 3693353  0.339
1987 Thomas NE, Bramson HN, Nairn AC, Greengard P, Fry DC, Mildvan AS, Kaiser ET. Distinguishing among protein kinases by substrate specificities. Biochemistry. 26: 4471-4. PMID 3663601 DOI: 10.1021/BI00388A043  0.515
1987 Albert KA, Nairn AC, Greengard P. The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization Proceedings of the National Academy of Sciences of the United States of America. 84: 7046-7050. PMID 3478678 DOI: 10.1073/PNAS.84.20.7046  0.566
1987 Lai Y, Nairn AC, Gorelick F, Greengard P. Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence Proceedings of the National Academy of Sciences of the United States of America. 84: 5710-5714. PMID 3475699 DOI: 10.1073/Pnas.84.16.5710  0.524
1987 Nairn AC, Greengard P. Purification and characterization of Ca2+/calmodulin-dependent protein kinase I from bovine brain Journal of Biological Chemistry. 262: 7273-7281. PMID 3108251  0.321
1987 Parks TP, Nairn AC, Greengard P, Jamieson JD. The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins Archives of Biochemistry and Biophysics. 255: 361-371. PMID 3036005 DOI: 10.1016/0003-9861(87)90404-8  0.605
1987 Nairn AC, Nichols RA, Brady MJ, Palfrey HC. Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells. The Journal of Biological Chemistry. 262: 14265-72. PMID 2443502  0.627
1987 Hammond C, Paupardin-Tritsch D, Nairn AC, Greengard P, Gerschenfeld HM. Cholecystokinin induces a decrease in Ca2+ current in snail neurons that appears to be mediated by protein kinase C. Nature. 325: 809-11. PMID 2434859 DOI: 10.1038/325809a0  0.576
1986 Woody CD, Bartfai T, Gruen E, Nairn AC. Intracellular injection of cGMP-dependent protein kinase results in increased input resistance in neurons of the mammalian motor cortex. Brain Research. 386: 379-85. PMID 3779415 DOI: 10.1016/0006-8993(86)90175-7  0.359
1986 Mackie K, Lai Y, Nairn AC, Greengard P, Pitt BR, Lazo JS. Protein phosphorylation in cultured endothelial cells. Journal of Cellular Physiology. 128: 367-74. PMID 3745280 DOI: 10.1002/jcp.1041280304  0.706
1986 Paupardin-Tritsch D, Hammond C, Gerschenfeld HM, Nairn AC, Greengard P. cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones. Nature. 323: 812-4. PMID 3022154 DOI: 10.1038/323812a0  0.551
1986 Hemmings HC, Nairn AC, Greengard P. Protein kinases and phosphoproteins in the nervous system. Research Publications - Association For Research in Nervous and Mental Disease. 64: 47-69. PMID 3014627  0.634
1986 Lai Y, Nairn AC, Greengard P. Autophosphorylation reversibly regulates the Ca2+/calmodulin-dependence of Ca2+/calmodulin-dependent protein kinase II Proceedings of the National Academy of Sciences of the United States of America. 83: 4253-4257. PMID 3012560 DOI: 10.1073/PNAS.83.12.4253  0.519
1986 Saez JC, Spray DC, Nairn AC, Hertzberg E, Greengard P, Bennett MV. cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide. Proceedings of the National Academy of Sciences of the United States of America. 83: 2473-7. PMID 3010311 DOI: 10.1073/Pnas.83.8.2473  0.603
1986 Walaas SI, Nairn AC, Greengard P. PCPP-260, a Purkinje cell-specific cyclic AMP-regulated membrane phosphoprotein of Mr 260,000. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 954-61. PMID 3009734 DOI: 10.1523/Jneurosci.06-04-00954.1986  0.697
1986 Walaas S, Nairn A, Greengard P. PCPP-260, a Purkinje cell-specific cyclic AMP-regulated membrane phosphoprotein of Mr 260,000 The Journal of Neuroscience. 6: 954-961. DOI: 10.1523/JNEUROSCI.06-04-00954.1986  0.62
1985 Nairn AC, Bhagat B, Palfrey HC. Identification of calmodulin-dependent protein kinase III and its major M(r) 100,000 substrate in mammalian tissues Proceedings of the National Academy of Sciences of the United States of America. 82: 7939-7943. PMID 3906654 DOI: 10.1073/Pnas.82.23.7939  0.493
1985 Nairn AC, Hemmings HC, Greengard P. Protein kinases in the brain. Annual Review of Biochemistry. 54: 931-76. PMID 2411213 DOI: 10.1146/annurev.bi.54.070185.004435  0.663
1985 Palfrey HC, Bhagat B, Nairn AC. Distribution of a major calmodulin-dependent protein kinase substrate (M(r) 100,000) in mammalian tissues and identification of a specific kinase Federation Proceedings. 44.  0.328
1984 Nairn AC, Grand RJ, Perry SV. The amino acid sequence of rabbit skeletal muscle calmodulin. Febs Letters. 167: 215-20. PMID 6698209 DOI: 10.1016/0014-5793(84)80129-5  0.337
1984 Hemmings HC, Nairn AC, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1. The Journal of Biological Chemistry. 259: 14491-7. PMID 6501303  0.67
1984 Hemmings HC, Nairn AC, Aswad DW, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 99-110. PMID 6319628 DOI: 10.1523/Jneurosci.04-01-00099.1984  0.756
1984 Albert KA, Wu WCS, Nairn AC, Greengard P. Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation Proceedings of the National Academy of Sciences of the United States of America. 81: 3622-3625. PMID 6233611 DOI: 10.1073/PNAS.81.12.3622  0.596
1984 Albert KA, Helmer-Matyjek E, Nairn AC, Müller TH, Haycock JW, Greene LA, Goldstein M, Greengard P. Calcium/phospholipid-dependent protein kinase (protein kinase C) phosphorylates and activates tyrosine hydroxylase. Proceedings of the National Academy of Sciences of the United States of America. 81: 7713-7. PMID 6151178 DOI: 10.1073/Pnas.81.24.7713  0.733
1984 Detre JA, Nairn AC, Aswad DW, Greengard P. Localization in mammalian brain of G-substrate, a specific substrate for guanosine 3',5'-cyclic monophosphate-dependent protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 2843-9. PMID 6094745 DOI: 10.1523/Jneurosci.04-11-02843.1984  0.664
1984 Detre J, Nairn A, Aswad D, Greengard P. Localization in mammalian brain of G-substrate, a specific substrate for guanosine 3',5'-cyclic monophosphate-dependent protein kinase The Journal of Neuroscience. 4: 2843-2849. DOI: 10.1523/JNEUROSCI.04-11-02843.1984  0.708
1984 Hemmings H, Nairn A, Aswad D, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus The Journal of Neuroscience. 4: 99-110. DOI: 10.1523/JNEUROSCI.04-01-00099.1984  0.725
1984 Nairn AC, Greengard P. Widespread tissue distribution of Ca2+/calmodulin-dependent protein kinase I that phosphorylates synapsin Federation Proceedings. 43.  0.336
1983 Nairn AC, Greengard P. Cyclic GMP-dependent protein phosphorylation in mammalian brain Federation Proceedings. 42: 3107-3113. PMID 6313433  0.417
1983 Walaas SI, Nairn AC, Greengard P. Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 302-11. PMID 6296332 DOI: 10.1523/Jneurosci.03-02-00302.1983  0.676
1983 Walaas SI, Nairn AC, Greengard P. Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. I. Particulate systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 291-301. PMID 6296331  0.645
1983 Dolphin AC, Detre JA, Schlichter DJ, Nairn AC, Yeh HH, Woodward DJ, Greengard P. Cyclic nucleotide-dependent protein kinases and some major substrates in the rat cerebellum after neonatal X-irradiation. Journal of Neurochemistry. 40: 577-81. PMID 6296321 DOI: 10.1111/j.1471-4159.1983.tb11321.x  0.703
1983 Walaas S, Nairn A, Greengard P. Regional distribution of calcium- and cyclic adenosine 3':5'- monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems The Journal of Neuroscience. 3: 302-311. DOI: 10.1523/JNEUROSCI.03-02-00302.1983  0.659
1983 Walaas S, Nairn A, Greengard P. Regional distribution of calcium- and cyclic adenosine 3':5'- monophosphate-regulated protein phosphorylation systems in mammalian brain. I. Particulate systems The Journal of Neuroscience. 3: 291-301. DOI: 10.1523/JNEUROSCI.03-02-00291.1983  0.659
1982 Wu WC, Walaas SI, Nairn AC, Greengard P. Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomes. Proceedings of the National Academy of Sciences of the United States of America. 79: 5249-53. PMID 6957862 DOI: 10.1073/pnas.79.17.5249  0.73
1982 Castellucci VF, Nairn A, Greengard P, Schwartz JH, Kandel ER. Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 2: 1673-81. PMID 6292379 DOI: 10.1523/Jneurosci.02-12-01673.1982  0.617
1982 Nairn AC, Detre JA, Casnellie JE, Greengard P. Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein. Nature. 299: 734-6. PMID 6289133 DOI: 10.1038/299734a0  0.542
1980 Nairn AC, Grand RJ, Wall CM, Perry SV. The relationship of the structure to the function of calmodulin in the myosin light chain kinase system. Annals of the New York Academy of Sciences. 356: 413-414. PMID 6940506 DOI: 10.1111/J.1749-6632.1980.Tb29653.X  0.333
1980 Kaczmarek LK, Jennings KR, Strumwasser F, Nairn AC, Walter U, Wilson FD, Greengard P. Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 77: 7487-91. PMID 6261262 DOI: 10.1073/pnas.77.12.7487  0.546
1980 Grand RJ, Nairn AC, Perry SV. The preparation of calmodulins from barley (Hordeum sp.) and basidiomycete fungi. Biochemical Journal. 185: 755-760. PMID 6248033 DOI: 10.1042/Bj1850755  0.388
1980 Castellucci VF, Kandel ER, Schwartz JH, Wilson FD, Nairn AC, Greengard P. Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia. Proceedings of the National Academy of Sciences of the United States of America. 77: 7492-6. PMID 6111794 DOI: 10.1073/Pnas.77.12.7492  0.592
1979 Perry SV, Grand RJ, Nairn AC, Vanaman TC, Wall CM. Calcium-binding proteins and the regulation of contractile activity. Biochemical Society Transactions. 7: 619-22. PMID 383543 DOI: 10.1042/Bst0070619  0.332
1979 Nairn AC, Perry SV. Calmodulin and myosin light-chain kinase of rabbit fast skeletal muscle Biochemical Journal. 179: 89-97. PMID 224861 DOI: 10.1042/Bj1790089  0.355
1979 Shenolikar S, Cohen PT, Cohen P, Nairn AC, Perry SV. The role of calmodulin in the structure and regulation of phosphorylase kinase from rabbit skeletal muscle. European Journal of Biochemistry / Febs. 100: 329-37. PMID 159817 DOI: 10.1111/J.1432-1033.1979.Tb04175.X  0.419
1977 Apps DK, Nairn AC. The equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver Biochemical Journal. 167: 87-93. PMID 201249 DOI: 10.1042/Bj1670087  0.319
Show low-probability matches.