Reisuke H. Takahashi, M.D., Ph.D. - Publications

Affiliations: 
Anatomic Pathology Tokyo Medical University, Los Angeles, CA, United States 

26/76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Takahashi RH, Yokotsuka M, Tobiume M, Sato Y, Hasegawa H, Nagao T, Gouras GK. Accumulation of cellular prion protein within β-amyloid oligomer plaques in aged human brains. Brain Pathology (Zurich, Switzerland). e12941. PMID 33624334 DOI: 10.1111/bpa.12941  0.751
2017 Willén K, Sroka A, Takahashi RH, Gouras GK. Heterogeneous Association of Alzheimer's Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses. Journal of Alzheimer's Disease : Jad. PMID 28869466 DOI: 10.3233/Jad-170262  0.819
2017 Takahashi RH, Nagao T, Gouras GK. Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease. Pathology International. PMID 28261941 DOI: 10.1111/Pin.12520  0.785
2013 Takahashi RH, Capetillo-Zarate E, Lin MT, Milner TA, Gouras GK. Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses. Plos One. 8: e51965. PMID 23372648 DOI: 10.1371/Journal.Pone.0051965  0.808
2011 Takahashi RH, Tobiume M, Sato Y, Sata T, Gouras GK, Takahashi H. Accumulation of cellular prion protein within dystrophic neurites of amyloid plaques in the Alzheimer's disease brain. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 31: 208-14. PMID 21062360 DOI: 10.1111/J.1440-1789.2010.01158.X  0.773
2010 Gouras GK, Tampellini D, Takahashi RH, Capetillo-Zarate E. Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease. Acta Neuropathologica. 119: 523-41. PMID 20354705 DOI: 10.1007/S00401-010-0679-9  0.839
2010 Takahashi RH, Capetillo-Zarate E, Lin MT, Milner TA, Gouras GK. Co-occurrence of Alzheimer's disease ß-amyloid and Ï„ pathologies at synapses. Neurobiology of Aging. 31: 1145-52. PMID 18771816 DOI: 10.1016/J.Neurobiolaging.2008.07.021  0.851
2010 Capetillo-Zarate E, Gracia L, Takahashi RH, Tampellini D, Milner TA, Banfelder JR, Gouras GK. O4-06-02: High resolution 3D volumetric visualization of the progression of intraneuronal Aβ and plaque pathology in brain Alzheimer's & Dementia. 6: S159-S160. DOI: 10.1016/J.Jalz.2010.05.497  0.767
2008 Capetillo-Zarate E, Takahashi RH, Almeida CG, Lin MT, Milner TA, Gouras GK. P4-260: Intraneuronal Aβ42 and microtubule-associated protein pathologies begin in synapses Alzheimer's & Dementia. 4: T747-T748. DOI: 10.1016/J.Jalz.2008.05.2329  0.802
2007 Tampellini D, Magrané J, Takahashi RH, Li F, Lin MT, Almeida CG, Gouras GK. Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. The Journal of Biological Chemistry. 282: 18895-906. PMID 17468102 DOI: 10.1074/Jbc.M700373200  0.829
2006 Almeida CG, Takahashi RH, Gouras GK. Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4277-88. PMID 16624948 DOI: 10.1523/Jneurosci.5078-05.2006  0.821
2006 Tampellini D, Magrane J, Takahashi RH, Li F, Almeida CG, Gouras GK. O4-06-08: Internalized antibodies to the Aβ domain of APP reduce intraneuronal Aβ and protect against synaptic alterations Alzheimer's & Dementia. 2: S89-S89. DOI: 10.1016/J.Jalz.2006.05.343  0.806
2005 Almeida CG, Tampellini D, Takahashi RH, Greengard P, Lin MT, Snyder EM, Gouras GK. Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses. Neurobiology of Disease. 20: 187-98. PMID 16242627 DOI: 10.1016/J.Nbd.2005.02.008  0.816
2005 Saura CA, Chen G, Malkani S, Choi SY, Takahashi RH, Zhang D, Gouras GK, Kirkwood A, Morris RG, Shen J. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6755-64. PMID 16033885 DOI: 10.1523/Jneurosci.1247-05.2005  0.733
2005 Gouras GK, Almeida CG, Takahashi RH. Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease. Neurobiology of Aging. 26: 1235-44. PMID 16023263 DOI: 10.1016/J.Neurobiolaging.2005.05.022  0.844
2004 Li F, Calingasan NY, Yu F, Mauck WM, Toidze M, Almeida CG, Takahashi RH, Carlson GA, Flint Beal M, Lin MT, Gouras GK. Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice. Journal of Neurochemistry. 89: 1308-12. PMID 15147524 DOI: 10.1111/J.1471-4159.2004.02455.X  0.804
2004 Takahashi RH, Almeida CG, Kearney PF, Yu F, Lin MT, Milner TA, Gouras GK. Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3592-9. PMID 15071107 DOI: 10.1523/Jneurosci.5167-03.2004  0.843
2004 Gouras G, LaFerla F, Strobel G, Busciglio J, Almeida C, Geula C, Stenh C, Lee D, D'Andrea M, Nagele B, Takahashi R, Hartmann T, LeBlanc A, Dineley K, Koudinov A. Intraneuronal Aβ accumulation-more evidence, less controversy? Alzheimer research forum live discussion Journal of Alzheimer's Disease. 6: 443-449. DOI: 10.3233/Jad-2004-6413  0.788
2004 Tampellini D, Almeida CG, Snyder EM, Takahashi RH, Manfredi G, Gouras GK. P3-322 Altered expression of synaptic and immediate early genes in a neuronal culture model of Alzheimer's disease Neurobiology of Aging. 25: S446-S447. DOI: 10.1016/S0197-4580(04)81472-6  0.787
2004 Almeida CG, Takahashi RH, Yu F, Lin MT, Greengard P, Snyder EM, Gouras GK. P3-314 Aβ42 accumulation in endosomes is associated with synaptic alterations Neurobiology of Aging. 25: S444. DOI: 10.1016/S0197-4580(04)81464-7  0.803
2004 Gouras GK, Almeida CG, Tampellini D, Takahashi RH. P3-313 Significance of intraneuronal Aβ accumulation in Alzheimer's disease Neurobiology of Aging. 25: S444. DOI: 10.1016/S0197-4580(04)81463-5  0.809
2004 Takahashi RH, G. Almeida C, Kearney PF, Yu F, Lin MT, Milner TA, Gouras GK. P1-195 Oligomerization of Alzheimer's Aβ within processes and synapses of cultured neurons and brain Neurobiology of Aging. 25: S151. DOI: 10.1016/S0197-4580(04)80508-6  0.729
2002 Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK. Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. The American Journal of Pathology. 161: 1869-79. PMID 12414533 DOI: 10.1016/S0002-9440(10)64463-X  0.739
2002 Feng J, Chi P, Blanpied TA, Xu Y, Magarinos AM, Ferreira A, Takahashi RH, Kao HT, McEwen BS, Ryan TA, Augustine GJ, Greengard P. Regulation of neurotransmitter release by synapsin III. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4372-80. PMID 12040043 DOI: 10.1523/Jneurosci.22-11-04372.2002  0.355
2002 Takahashi RH, Nam EE, Edgar M, Gouras GK. Alzheimer beta-amyloid peptides: normal and abnormal localization. Histology and Histopathology. 17: 239-46. PMID 11813874 DOI: 10.14670/Hh-17.239  0.622
1996 Takahashi RH, Sawa H, Kuroda S, Saito H, Fujita M, Fujioka Y, Fukatsu R, Nagashima K. Pathologic processes leading to cerebral hemorrhage in amyloid angiopathy Neuropathology. 16: 99-105.  0.345
Low-probability matches (unlikely to be authored by this person)
1999 Takahashi H, Iwata T, Kitagawa Y, Takahashi RH, Sato Y, Wakabayashi H, Takashima M, Kido H, Nagashima K, Kenney K, Gibbs CJ, Kurata T. Increased Levels of ɛ and γ Isoforms of 14-3-3 Proteins in Cerebrospinal Fluid in Patients with Creutzfeldt-Jakob Disease Clinical Diagnostic Laboratory Immunology. 6: 983-985. DOI: 10.1128/Cdli.6.6.983-985.1999  0.287
1999 Takahashi H, Takahashi RH, Hasegawa H, Horiuchi M, Shinagawa M, Yokoyama T, Kimura K, Haritani M, Kurata T, Nagashima K. Characterization of antibodies raised against bovine-PrP-peptides. Journal of Neurovirology. 5: 300-7. PMID 10414520 DOI: 10.3109/13550289909015816  0.273
2019 Matsunaga R, Takahashi Y, Takahashi RH, Nagao T, Shishido T, Tateiwa T, Pezzotti G, Yamamoto K. A new method for diagnosing biochemical abnormalities of anterior cruciate ligament (ACL) in human knees: a Raman spectroscopic study. Acta Biomaterialia. PMID 31525535 DOI: 10.1016/J.Actbio.2019.09.016  0.217
2000 Takahashi H, Iwata T, Kitagawa Y, Shoya Y, Takahashi RH, Nagashima K, Kurata T. Monoclonal antibodies against topoisomerase I suppressed DNA relaxation and HIV-1 cDNA synthesis. Hybridoma. 19: 331-4. PMID 11001406 DOI: 10.1089/027245700429882  0.199
1999 Takahashi RH, Nagashima K, Kurata T, Takahashi H. Analysis of human lymphotropic T-cell virus type II-like particle production by recombinant baculovirus-infected insect cells. Virology. 256: 371-80. PMID 10191202 DOI: 10.1006/Viro.1999.9655  0.199
2012 Takahashi RH, Matsubayashi J, Yokotsuka M, Tachibana M, Kusama H, Nagao T. An intrapelvic extraintestinal gastrointestinal stromal tumor of undetermined origin: diagnosis by prostate needle biopsy. Pathology, Research and Practice. 208: 736-40. PMID 23057997 DOI: 10.1016/J.Prp.2012.09.003  0.192
1997 Takahashi RH, Sawa H, Takada A, Kitabatake A, Nagashima K. Expression of amyloid precursor protein mRNA in vascular smooth muscle cells of the human brain Neuropathology. 17: 11-14.  0.189
1999 Takahashi RH, Nagashima K, Kurata T, Takahashi H. Analysis of HTLV-II-like particle production by recombinant baculovirus-infected insect cells. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 20: A74. DOI: 10.1097/00042560-199904010-00276  0.168
1999 Takahashi H, Iwata T, Kitagawa Y, Takahashi RH, Sato Y, Wakabayashi H, Takashima M, Kido H, Nagashima K, Kenney K, Gibbs CJ, Kurata T. Increased levels of epsilon and gamma isoforms of 14-3-3 proteins in cerebrospinal fluid in patients with Creutzfeldt-Jakob disease. Clinical and Diagnostic Laboratory Immunology. 6: 983-5. PMID 10548598  0.158
2024 Craig RA, De Vicente J, Estrada AA, Feng JA, Lexa KW, Canet MJ, Dowdle WE, Erickson RI, Flores BN, Haddick PCG, Kane LA, Lewcock JW, Moerke NJ, Poda SB, Sweeney Z, ... Takahashi RH, et al. Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases. Journal of Medicinal Chemistry. PMID 38511649 DOI: 10.1021/acs.jmedchem.3c02422  0.149
2015 Toyota H, Sudo K, Kojima K, Yanase N, Nagao T, Takahashi RH, Iobe H, Kuwabara T, Kakiuchi T, Mizuguchi J. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. Apoptosis : An International Journal On Programmed Cell Death. 20: 444-54. PMID 25547913 DOI: 10.1007/s10495-014-1082-0  0.108
2022 Craig RA, Fox BM, Hu C, Lexa KW, Osipov M, Thottumkara AP, Larhammar M, Miyamoto T, Rana A, Kane LA, Yulyaningsih E, Solanoy H, Nguyen H, Chau R, Earr T, ... ... Takahashi RH, et al. Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis. Journal of Medicinal Chemistry. PMID 36469401 DOI: 10.1021/acs.jmedchem.2c01056  0.107
2020 Takahashi RH, Grandner JM, Bobba S, Liu Y, Beroza P, Zhang D, Ma S. Novel Homodimer Metabolites of GDC-0994 via Cytochrome P450-Catalyzed Radical Coupling. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32234735 DOI: 10.1124/dmd.119.090019  0.099
2017 Ly JQ, Messick K, Qin A, Takahashi RH, Choo EF. Utility of CYP3A4 and PXR-CAR-CYP3A4/3A7 transgenic mouse models to assess the magnitude of CYP3A4 mediated drug-drug interactions. Molecular Pharmaceutics. PMID 28345929 DOI: 10.1021/acs.molpharmaceut.7b00006  0.086
2008 Takahashi RH, Bains OS, Pfeifer TA, Grigliatti TA, Reid RE, Riggs KW. Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 991-4. PMID 18322072 DOI: 10.1124/dmd.108.020388  0.077
2017 Takahashi RH, Halladay JS, Siu M, Chen Y, Hop CE, Khojasteh SC, Ma S. Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28188299 DOI: 10.1124/Dmd.116.074336  0.077
2015 Takahashi RH, Ma S, Robinson SJ, Yue Q, Choo EF, Khojasteh SC. Elucidating the Mechanisms of Formation for Two Unusual P450-Mediated Fused Ring Metabolites of GDC-0623, a MEK Inhibitor. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26438627 DOI: 10.1124/Dmd.115.067181  0.072
2008 Bains OS, Takahashi RH, Pfeifer TA, Grigliatti TA, Reid RE, Riggs KW. Two allelic variants of aldo-keto reductase 1A1 exhibit reduced in vitro metabolism of daunorubicin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 904-10. PMID 18276838 DOI: 10.1124/dmd.107.018895  0.069
2017 Takahashi RH, Shahidi-Latham S, Wong S, Chang JH. Applying Stable Isotope Labeled Amino Acids in Micropatterned Hepatocyte Co-Culture to Directly Determine the Degradation Rate Constant for CYP3A4. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28289057 DOI: 10.1124/dmd.116.074393  0.067
2021 Takahashi RH, Forrest WF, Smith AD, Badée J, Qiu N, Schmidt S, Collier AC, Parrott N, Fowler S. Characterization of Hepatic UDP-Glucuronosyl Transferase Enzyme Abundance - Activity Correlations and Population Variability using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34187837 DOI: 10.1124/dmd.121.000474  0.066
2020 Zhang H, Wolford C, Basit A, Li AP, Fan PW, Takahashi RH, Khojasteh SC, Smith BJ, Murray BP, Thummel K, Prasad B. Regional proteomic quantification of clinically relevant non-cytochrome P450 enzymes along the human small intestine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32350063 DOI: 10.1124/Dmd.120.090738  0.065
2009 Takahashi RH, Grigliatti TA, Reid RE, Riggs KW. The effect of allelic variation in aldo-keto reductase 1C2 on the in vitro metabolism of dihydrotestosterone. The Journal of Pharmacology and Experimental Therapeutics. 329: 1032-9. PMID 19258517 DOI: 10.1124/jpet.109.150995  0.06
2017 Takahashi RH, Wang X, Segraves NL, Wang J, Chang JH, Khojasteh SC, Ma S. CYP1A1-Mediated Intramolecular Rearrangement of Aminoazepane in GDC-0339. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28790146 DOI: 10.1124/Dmd.117.076786  0.06
2011 Almeida AC, Duarte AR, Duczmal LH, Oliveira FL, Takahashi RH. Data-driven inference for the spatial scan statistic. International Journal of Health Geographics. 10: 47. PMID 21806835 DOI: 10.1186/1476-072X-10-47  0.059
2021 Nakaguro M, Tanigawa M, Hirai H, Yamamoto Y, Urano M, Takahashi RH, Sukeda A, Okumura Y, Honda S, Tasaki K, Shimizu A, Tsukahara K, Tada Y, Matsubayashi J, Faquin WC, et al. The Diagnostic Utility of RAS Q61R Mutation-specific Immunohistochemistry in Epithelial-Myoepithelial Carcinoma. The American Journal of Surgical Pathology. PMID 33481388 DOI: 10.1097/PAS.0000000000001673  0.045
2014 Higuchi K, Urano M, Takahashi RH, Oshiro H, Matsubayashi J, Nagai T, Obikane H, Shimojo H, Nagao T. Cytological features of mammary analogue secretory carcinoma of salivary gland: fine-needle aspiration of seven cases. Diagnostic Cytopathology. 42: 846-55. PMID 24585770 DOI: 10.1002/dc.23139  0.043
2013 Wageck BB, de Noronha M, Lopes AD, da Cunha RA, Takahashi RH, Costa LO. Cross-cultural adaptation and measurement properties of the Brazilian Portuguese Version of the Victorian Institute of Sport Assessment-Patella (VISA-P) scale. The Journal of Orthopaedic and Sports Physical Therapy. 43: 163-71. PMID 23321783 DOI: 10.2519/jospt.2013.4287  0.041
2019 Bart AG, Takahashi RH, Wang X, Scott EE. Human Cytochrome P450 1A1 Adapts Active Site for Atypical Nonplanar Substrate. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31757797 DOI: 10.1124/Dmd.119.089607  0.039
2016 Takahashi RH, Ma S, Yue Q, Kim-Kang H, Yi Y, Ly J, Boggs JW, Fettes A, McClory A, Deng Y, Hop CE, Khojasteh SC, Choo EF. Absorption, metabolism and excretion of cobimetinib, an oral MEK inhibitor, in rats and dogs. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-16. PMID 27055783 DOI: 10.3109/00498254.2016.1157645  0.037
2018 Wang J, Takahashi RH, DeMent K, Gustafson A, Kenny JR, Wong SG, Yan Z. Development of a mass spectrometry-based tryptophan 2, 3-dioxygenase assay using liver cytosol from multiple species. Analytical Biochemistry. PMID 29959909 DOI: 10.1016/j.ab.2018.06.025  0.036
2023 Wang S, Argikar UA, Cheruzel L, Cho S, Crouch RD, Dhaware D, Heck CJS, Johnson KM, Kalgutkar AS, King L, Liu J, Ma B, Maw H, Miller GP, Seneviratne HK, ... Takahashi RH, et al. Bioactivation and reactivity research advances - 2022 year in review‡. Drug Metabolism Reviews. 1-34. PMID 37608698 DOI: 10.1080/03602532.2023.2244193  0.036
2020 Basit A, Neradugomma NK, Wolford C, Fan PW, Murray B, Takahashi RH, Khojasteh SC, Smith BJ, Heyward S, Totah RA, Kelly EJ, Prasad B. CHARACTERIZATION OF DIFFERENTIAL TISSUE ABUNDANCE OF MAJOR NON-CYP ENZYMES IN HUMAN. Molecular Pharmaceutics. PMID 32955894 DOI: 10.1021/Acs.Molpharmaceut.0C00559  0.035
2015 Takahashi RH, Choo EF, Ma S, Wong S, Halladay J, Deng A, Rooney I, Gates M, Hop CE, Khojasteh SC, Dresser M, Musib L. Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26451002 DOI: 10.1124/Dmd.115.066282  0.034
2023 Takahashi RH, Malhi V, Liederer BM, Cho S, Deng Y, Dean B, Nugteren J, Yost E, Al-Sayah MA, Sane R, Kshirsagar S, Ma S, Musib L. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 37524543 DOI: 10.1124/dmd.122.001175  0.031
2021 Ishida T, Tateiwa T, Takahashi Y, Takahashi RH, Sano K, Shishido T, Masaoka T, Yamamoto K. IL-17A-Mediated Immune-Inflammatory Periarticular Mass and Osteolysis From Impingement in Ceramic-On-Ceramic Total Hip Arthroplasty. Arthroplasty Today. 11: 15-19. PMID 34409142 DOI: 10.1016/j.artd.2021.06.018  0.03
2019 Badée J, Qiu N, Collier AC, Takahashi RH, Forrest WF, Parrott N, Schmidt S, Fowler S. Characterization of the Ontogeny of Hepatic UDP-Glucuronosyltransferase Enzymes Based on Glucuronidation Activity Measured in Human Liver Microsomes. Journal of Clinical Pharmacology. 59: S42-S55. PMID 31502688 DOI: 10.1002/jcph.1493  0.029
2008 Shibayama J, Takahashi R, Yamauchi J, Nakano H. Frequency-Dependent Locally One-Dimensional FDTD Implementation With a Combined Dispersion Model for the Analysis of Surface Plasmon Waveguides Ieee Photonics Technology Letters. 20: 824-826. DOI: 10.1109/LPT.2008.921830  0.028
2023 Khojasteh SC, Argikar UA, Cheruzel L, Cho S, Crouch RD, Dhaware D, Heck CJS, Johnson KM, Kalgutkar AS, King L, Liu J, Ma B, Maw H, Miller GP, Seneviratne HK, ... Takahashi RH, et al. Biotransformation research advances - 2022 year in review. Drug Metabolism Reviews. 1-75. PMID 37737116 DOI: 10.1080/03602532.2023.2262161  0.027
2011 Pereira HM, Menacho MdO, Takahashi RH, Cardoso JR. Handgrip strength evaluation on tennis players using different recommendations Revista Brasileira De Medicina Do Esporte. 17: 184-188. DOI: 10.1590/S1517-86922011000300007  0.025
2008 Wanner EF, Guimarães FG, Takahashi RH, Fleming PJ. Local search with quadratic approximations into memetic algorithms for optimization with multiple criteria. Evolutionary Computation. 16: 185-224. PMID 18554100 DOI: 10.1162/Evco.2008.16.2.185  0.024
2018 Takahashi RH, Chang JH, Pang J, Liang X, Ma S. A Case Study of Overestimating Absorption and Circulating Metabolites Due to the Preferential Absorption of Radiolabeled Drug in a Mass Balance Study. Drug Metabolism Letters. PMID 30499424 DOI: 10.2174/1872312813666181129162237  0.022
2019 Liu Y, Badée J, Takahashi RH, Schmidt S, Parrott N, Fowler S, Mackenzie PI, Coughtrie MWH, Collier AC. Coexpression of Human Hepatic Uridine Diphosphate Glucuronosyltransferase Proteins: Implications for Ontogenetic Mechanisms and Isoform Coregulation. Journal of Clinical Pharmacology. PMID 31879975 DOI: 10.1002/jcph.1571  0.021
2011 Duczmal LH, Moreira GJ, Burgarelli D, Takahashi RH, Magalhães FC, Bodevan EC. Voronoi distance based prospective space-time scans for point data sets: a dengue fever cluster analysis in a southeast Brazilian town. International Journal of Health Geographics. 10: 29. PMID 21513556 DOI: 10.1186/1476-072X-10-29  0.019
2017 Takahashi R, Khojasteh C, Wright M, Hop C, Ma S. Mixed Matrix Method Provides A Reliable Metabolite Exposure Comparison for Assessment of Metabolite-in-Safety Testing (MIST). Drug Metabolism Letters. PMID 28699487 DOI: 10.2174/1872312811666170710193229  0.015
2017 Takahashi R, Khojasteh C, Wright M, Hop C, Ma S. Mixed Matrix Method Provides A Reliable Metabolite Exposure Comparison for Assessment of Metabolite-in-Safety Testing (MIST). Drug Metabolism Letters. PMID 28699487 DOI: 10.2174/1872312811666170710193229  0.015
2001 Teixeira RD, Braga AP, Takahashi RH, Saldanha RR. Recent advances in the MOBJ algorithm for training artificial neural networks. International Journal of Neural Systems. 11: 265-70. PMID 11574964 DOI: 10.1142/S0129065701000709  0.015
2009 Cardoso RT, da Cruz AR, Wanner EF, Takahashi RH. Multi-objective evolutionary optimization of biological pest control with impulsive dynamics in soybean crops. Bulletin of Mathematical Biology. 71: 1463-81. PMID 19267163 DOI: 10.1007/s11538-009-9409-7  0.014
2014 Martins FV, Carrano EG, Wanner EF, Takahashi RH, Mateus GR, Nakamura FG. On a vector space representation in genetic algorithms for sensor scheduling in wireless sensor networks. Evolutionary Computation. 22: 361-403. PMID 24102647 DOI: 10.1162/EVCO_a_00112  0.014
2009 Araujo MC, Wanner EF, Guimarães FG, Takahashi RH. Constrained optimization based on quadratic approximations in genetic algorithms Studies in Computational Intelligence. 198: 193-217. DOI: 10.1007/978-3-642-00619-7_9  0.01
2008 Vieira DA, Takahashi RH, Palade V, Vasconcelos JA, Caminhas WM. The Q-norm complexity measure and the minimum gradient method: a novel approach to the machine learning structural risk minimization problem. Ieee Transactions On Neural Networks / a Publication of the Ieee Neural Networks Council. 19: 1415-30. PMID 18701371 DOI: 10.1109/TNN.2008.2000442  0.01
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