Alfredo Kirkwood - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Plasticity

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bridi MCD, Hong S, Severin D, Moreno C, Contreras A, Kirkwood A. Blockade of GluN2B-containing NMDA receptors prevents potentiation and depression of responses during ocular dominance plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 39117456 DOI: 10.1523/JNEUROSCI.0021-23.2024  0.443
2024 Lamsa KP, Kirkwood A, Sjöström PJ. Editorial: Insights in synaptic neuroscience 2022. Frontiers in Synaptic Neuroscience. 16: 1432259. PMID 38915459 DOI: 10.3389/fnsyn.2024.1432259  0.419
2024 Araki Y, Rajkovich KE, Gerber EE, Gamache TR, Johnson RC, Tran THN, Liu B, Zhu Q, Hong I, Kirkwood A, Huganir R. SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity. Science (New York, N.Y.). 383: eadk1291. PMID 38422154 DOI: 10.1126/science.adk1291  0.439
2024 Mesik L, Parkins S, Severin D, Grier BD, Ewall G, Kotha S, Wesselborg C, Moreno C, Jaoui Y, Felder A, Huang B, Johnson MB, Harrigan TP, Knight AE, Lani SW, ... ... Kirkwood A, et al. Transcranial low-intensity focused ultrasound (LIFU) stimulation of the visual thalamus produces long-term depression of thalamocortical synapses in the adult visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 38316559 DOI: 10.1523/JNEUROSCI.0784-23.2024  0.808
2023 Araki Y, Gerber EE, Rajkovich KE, Hong I, Johnson RC, Lee HK, Kirkwood A, Huganir RL. Mouse models of -related intellectual disability. Proceedings of the National Academy of Sciences of the United States of America. 120: e2308891120. PMID 37669379 DOI: 10.1073/pnas.2308891120  0.767
2023 Araki Y, Gerber EE, Rajkovich KE, Hong I, Johnson RC, Lee HK, Kirkwood A, Huganir RL. Mouse models of -related intellectual disability. Biorxiv : the Preprint Server For Biology. PMID 37293116 DOI: 10.1101/2023.05.25.542312  0.767
2023 Valdivia G, Ardiles AO, Idowu A, Salazar C, Lee HK, Gallagher M, Palacios AG, Kirkwood A. mGluR-dependent plasticity in rodent models of Alzheimer's disease. Frontiers in Synaptic Neuroscience. 15: 1123294. PMID 36937569 DOI: 10.3389/fnsyn.2023.1123294  0.828
2023 Yang L, Liu W, Shi L, Wu J, Zhang W, Chuang YA, Redding-Ochoa J, Kirkwood A, Savonenko AV, Worley PF. NMDAR-Arc signaling is required for Memory Updating and is disrupted in Alzheimer's Disease. Biological Psychiatry. PMID 36796600 DOI: 10.1016/j.biopsych.2023.02.008  0.41
2022 Spahic H, Parmar P, Miller S, Emerson PC, Lechner C, St Pierre M, Rastogi N, Nugent M, Duck SA, Kirkwood A, Chavez-Valdez R. Dysregulation of ErbB4 Signaling Pathway in the Dorsal Hippocampus after Neonatal Hypoxia-Ischemia and Late Deficits in PV Interneurons, Synaptic Plasticity and Working Memory. International Journal of Molecular Sciences. 24. PMID 36613949 DOI: 10.3390/ijms24010508  0.358
2022 Nugent FS, Kirkwood A, Lupica CR, Sjöström PJ. Editorial: The synaptic basis of neuropathology. Frontiers in Synaptic Neuroscience. 14: 1043480. PMID 36311440 DOI: 10.3389/fnsyn.2022.1043480  0.416
2022 Hong SZ, Mesik L, Grossman CD, Cohen JY, Lee B, Severin D, Lee HK, Hell JW, Kirkwood A. Author Correction: Norepinephrine potentiates and serotonin depresses visual cortical responses by transforming eligibility traces. Nature Communications. 13: 4034. PMID 35821244 DOI: 10.1038/s41467-022-31777-4  0.746
2022 Hong SZ, Mesik L, Grossman CD, Cohen JY, Lee B, Lee HK, Hell JW, Kirkwood A. Norepinephrine potentiates and serotonin depresses visual cortical responses by transforming eligibility traces. Nature Communications. 13: 3202. PMID 35680879 DOI: 10.1038/s41467-022-30827-1  0.816
2021 Severin D, Hong SZ, Roh SE, Huang S, Zhou J, Bridi MCD, Hong I, Murase S, Robertson S, Haberman RP, Huganir RL, Gallagher M, Quinlan EM, Worley P, Kirkwood A. All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34508001 DOI: 10.1073/pnas.2105388118  0.773
2021 Mihalas S, Ardiles A, He K, Palacios A, Kirkwood A. A Multisubcellular Compartment Model of AMPA Receptor Trafficking for Neuromodulation of Hebbian Synaptic Plasticity. Frontiers in Synaptic Neuroscience. 13: 703621. PMID 34456706 DOI: 10.3389/fnsyn.2021.703621  0.835
2020 Huang S, Kirkwood A. Endocannabinoid Signaling Contributes to Experience-Induced Increase of Synaptic Release Sites From Parvalbumin Interneurons in Mouse Visual Cortex. Frontiers in Cellular Neuroscience. 14: 571133. PMID 33192316 DOI: 10.3389/fncel.2020.571133  0.498
2020 Severin D, Gallagher M, Kirkwood A. Afterhyperpolarization amplitude in CA1 pyramidal cells of aged Long-Evans rats characterized for individual differences. Neurobiology of Aging. 96: 43-48. PMID 32932137 DOI: 10.1016/j.neurobiolaging.2020.07.022  0.338
2020 Hong S, Huang S, Severin D, Kirkwood A. Pull-push neuromodulation of cortical plasticity enables rapid bi-directional shifts in ocular dominance. Elife. 9. PMID 32432545 DOI: 10.7554/Elife.54455  0.587
2020 Bridi MS, Shin S, Huang S, Kirkwood A. Dynamic Recovery from Depression Enables Rate Encoding in Inhibitory Synapses. Iscience. 23: 100940. PMID 32163896 DOI: 10.1016/J.Isci.2020.100940  0.821
2020 Kirkwood A. Decision letter: Group III metabotropic glutamate receptors gate long-term potentiation and synaptic tagging/capture in rat hippocampal area CA2 Elife. DOI: 10.7554/Elife.55344.Sa1  0.444
2020 Hong SZ, Huang S, Severin D, Kirkwood A. Author response: Pull-push neuromodulation of cortical plasticity enables rapid bi-directional shifts in ocular dominance Elife. DOI: 10.7554/Elife.54455.Sa2  0.433
2019 Lee HK, Kirkwood A. Mechanisms of Homeostatic Synaptic Plasticity . Frontiers in Cellular Neuroscience. 13: 520. PMID 31849610 DOI: 10.3389/fncel.2019.00520  0.818
2019 Bridi MCD, Zong FJ, Min X, Luo N, Tran T, Qiu J, Severin D, Zhang XT, Wang G, Zhu ZJ, He KW, Kirkwood A. Daily Oscillation of the Excitation-Inhibition Balance in Visual Cortical Circuits. Neuron. PMID 31831331 DOI: 10.1016/j.neuron.2019.11.011  0.77
2019 Tran T, Bridi M, Koh MT, Gallagher M, Kirkwood A. Reduced cognitive performance in aged rats correlates with increased excitation/inhibition ratio in the dentate gyrus in response to lateral entorhinal input. Neurobiology of Aging. 82: 120-127. PMID 31476654 DOI: 10.1016/j.neurobiolaging.2019.07.010  0.414
2018 Tran T, Gallagher M, Kirkwood A. Enhanced postsynaptic inhibitory strength in hippocampal principal cells in high-performing aged rats. Neurobiology of Aging. 70: 92-101. PMID 30007169 DOI: 10.1016/j.neurobiolaging.2018.06.008  0.392
2018 Bridi MCD, de Pasquale R, Lantz CL, Gu Y, Borrell A, Choi SY, He K, Tran T, Hong SZ, Dykman A, Lee HK, Quinlan EM, Kirkwood A. Two distinct mechanisms for experience-dependent homeostasis. Nature Neuroscience. PMID 29760525 DOI: 10.1038/S41593-018-0150-0  0.831
2017 Chen Y, Granger AJ, Tran T, Saulnier JL, Kirkwood A, Sabatini BL. Endogenous Gαq-Coupled Neuromodulator Receptors Activate Protein Kinase A. Neuron. PMID 29154125 DOI: 10.1016/J.Neuron.2017.10.023  0.343
2017 Li S, Wang L, Tie X, Sohya K, Lin X, Kirkwood A, Jiang B. Brief novel visual experience fundamentally changes synaptic plasticity in the mouse visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28821676 DOI: 10.1523/Jneurosci.0334-17.2017  0.623
2017 Gao M, Whitt JL, Huang S, Lee A, Mihalas S, Kirkwood A, Lee HK. Experience-dependent homeostasis of 'noise' at inhibitory synapses preserves information coding in adult visual cortex. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28093550 DOI: 10.1098/Rstb.2016.0156  0.822
2016 Gu Y, Tran T, Murase S, Borrell A, Kirkwood A, Quinlan EM. Neuregulin-Dependent Regulation of Fast-Spiking Interneuron Excitability Controls the Timing of the Critical Period. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 10285-10295. PMID 27707966 DOI: 10.1523/Jneurosci.4242-15.2016  0.747
2016 Posada-Duque RA, Ramirez O, Härtel S, Inestrosa NC, Bodaleo F, González-Billault C, Kirkwood A, Cardona-Gómez GP. CDK5 downregulation enhances synaptic plasticity. Cellular and Molecular Life Sciences : Cmls. PMID 27506619 DOI: 10.1007/S00018-016-2333-8  0.499
2016 Wang H, Ardiles AO, Yang S, Tran T, Posada-Duque R, Valdivia G, Baek M, Chuang YA, Palacios AG, Gallagher M, Worley P, Kirkwood A. Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1723-9. PMID 26843652 DOI: 10.1523/Jneurosci.0878-15.2016  0.844
2015 Huang S, Hokenson K, Bandyopadhyay S, Russek SJ, Kirkwood A. Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15916-20. PMID 26631472 DOI: 10.1523/Jneurosci.1813-15.2015  0.444
2015 He K, Huertas M, Hong SZ, Tie X, Hell JW, Shouval H, Kirkwood A. Distinct Eligibility Traces for LTP and LTD in Cortical Synapses. Neuron. 88: 528-38. PMID 26593091 DOI: 10.1016/J.Neuron.2015.09.037  0.782
2015 Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK. Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11346-57. PMID 26269641 DOI: 10.1523/Jneurosci.5289-14.2015  0.816
2015 Kirkwood A. Balancing excitation and inhibition. Neuron. 86: 348-50. PMID 25905806 DOI: 10.1016/j.neuron.2015.04.009  0.425
2014 Yang S, Yang S, Park JS, Kirkwood A, Bao S. Failed stabilization for long-term potentiation in the auditory cortex of FMR1 knockout mice. Plos One. 9: e104691. PMID 25115962 DOI: 10.1371/Journal.Pone.0104691  0.693
2014 Huang S, Rozas C, Treviño M, Contreras J, Yang S, Song L, Yoshioka T, Lee HK, Kirkwood A. Associative Hebbian synaptic plasticity in primate visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7575-9. PMID 24872561 DOI: 10.1523/Jneurosci.0983-14.2014  0.843
2014 Wang H, Megill A, Wong PC, Kirkwood A, Lee HK. Postsynaptic target specific synaptic dysfunctions in the CA3 area of BACE1 knockout mice. Plos One. 9: e92279. PMID 24637500 DOI: 10.1371/Journal.Pone.0092279  0.797
2014 Huertas MA, Schwettmann S, Kirkwood A, Shouval H. Stable reinforcement learning via temporal competition between LTP and LTD traces Bmc Neuroscience. 15. DOI: 10.1186/1471-2202-15-S1-O12  0.413
2014 Mihalas S, Millman D, Iyer R, Kirkwood A, Niebur E. Nonconservative Neuronal Networks During Up-States Self-Organize Near Critical Points Criticality in Neural Systems. 437-464. DOI: 10.1002/9783527651009.ch21  0.746
2013 Huang S, Huganir RL, Kirkwood A. Adrenergic gating of Hebbian spike-timing-dependent plasticity in cortical interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13171-8. PMID 23926270 DOI: 10.1523/Jneurosci.5741-12.2013  0.552
2013 Yang S, Megill A, Ardiles AO, Ransom S, Tran T, Koh MT, Lee HK, Gallagher M, Kirkwood A. Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12670-8. PMID 23904603 DOI: 10.1523/Jneurosci.1086-13.2013  0.789
2013 Gu Y, Huang S, Chang MC, Worley P, Kirkwood A, Quinlan EM. Obligatory role for the immediate early gene NARP in critical period plasticity. Neuron. 79: 335-46. PMID 23889936 DOI: 10.1016/J.Neuron.2013.05.016  0.814
2013 Megill A, Lee T, DiBattista AM, Song JM, Spitzer MH, Rubinshtein M, Habib LK, Capule CC, Mayer M, Turner RS, Kirkwood A, Yang J, Pak DT, Lee HK, Hoe HS. A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9306-18. PMID 23719799 DOI: 10.1523/Jneurosci.1615-12.2013  0.796
2013 Ardiles AO, Ewer J, Acosta ML, Kirkwood A, Martinez AD, Ebensperger LA, Bozinovic F, Lee TM, Palacios AG. Octodon degus (Molina 1782): a model in comparative biology and biomedicine. Cold Spring Harbor Protocols. 2013: 312-8. PMID 23547147 DOI: 10.1101/pdb.emo071357  0.7
2012 LeGates TA, Altimus CM, Wang H, Lee HK, Yang S, Zhao H, Kirkwood A, Weber ET, Hattar S. Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. 491: 594-8. PMID 23151476 DOI: 10.1038/Nature11673  0.767
2012 Guo Y, Huang S, de Pasquale R, McGehrin K, Lee HK, Zhao K, Kirkwood A. Dark exposure extends the integration window for spike-timing-dependent plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15027-35. PMID 23100424 DOI: 10.1523/Jneurosci.2545-12.2012  0.826
2012 Ardiles AO, Tapia-Rojas CC, Mandal M, Alexandre F, Kirkwood A, Inestrosa NC, Palacios AG. Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 13835-40. PMID 22869717 DOI: 10.1073/pnas.1201209109  0.738
2012 Wang H, Megill A, He K, Kirkwood A, Lee HK. Consequences of inhibiting amyloid precursor protein processing enzymes on synaptic function and plasticity. Neural Plasticity. 2012: 272374. PMID 22792491 DOI: 10.1155/2012/272374  0.789
2012 Huang S, Treviño M, He K, Ardiles A, Pasquale Rd, Guo Y, Palacios A, Huganir R, Kirkwood A. Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex. Neuron. 73: 497-510. PMID 22325202 DOI: 10.1016/J.Neuron.2011.11.023  0.845
2011 Lee HK, Kirkwood A. AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Seminars in Cell & Developmental Biology. 22: 514-20. PMID 21856433 DOI: 10.1016/j.semcdb.2011.06.007  0.833
2011 Kulkarni M, Zhang K, Kirkwood A. Single-cell persistent activity in anterodorsal thalamus. Neuroscience Letters. 498: 179-84. PMID 21362457 DOI: 10.1016/j.neulet.2011.02.051  0.432
2011 Lorca RA, Rozas C, Loyola S, Moreira-Ramos S, Zeise ML, Kirkwood A, Huidobro-Toro JP, Morales B. Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region. The European Journal of Neuroscience. 33: 1175-85. PMID 21324005 DOI: 10.1111/J.1460-9568.2010.07589.X  0.447
2011 Muñoz P, Humeres A, Elgueta C, Kirkwood A, Hidalgo C, Núñez MT. Iron mediates N-methyl-D-aspartate receptor-dependent stimulation of calcium-induced pathways and hippocampal synaptic plasticity. The Journal of Biological Chemistry. 286: 13382-92. PMID 21296883 DOI: 10.1074/Jbc.M110.213785  0.4
2010 Millman D, Mihalas S, Kirkwood A, Niebur E. Self-organized criticality occurs in non-conservative neuronal networks during Up states. Nature Physics. 6: 801-805. PMID 21804861 DOI: 10.1038/Nphys1757  0.788
2010 Pawlak V, Wickens JR, Kirkwood A, Kerr JN. Timing is not Everything: Neuromodulation Opens the STDP Gate. Frontiers in Synaptic Neuroscience. 2: 146. PMID 21423532 DOI: 10.3389/Fnsyn.2010.00146  0.478
2010 Huang S, Gu Y, Quinlan EM, Kirkwood A. A refractory period for rejuvenating GABAergic synaptic transmission and ocular dominance plasticity with dark exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16636-42. PMID 21148002 DOI: 10.1523/Jneurosci.4384-10.2010  0.777
2010 Zhang D, Zhang C, Ho A, Kirkwood A, Südhof TC, Shen J. Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction. Journal of Neurochemistry. 115: 1215-21. PMID 20854432 DOI: 10.1111/J.1471-4159.2010.07011.X  0.511
2010 Jiang B, Huang S, de Pasquale R, Millman D, Song L, Lee HK, Tsumoto T, Kirkwood A. The maturation of GABAergic transmission in visual cortex requires endocannabinoid-mediated LTD of inhibitory inputs during a critical period. Neuron. 66: 248-59. PMID 20435001 DOI: 10.1016/J.Neuron.2010.03.021  0.789
2009 Savonenko A, Munoz P, Melnikova T, Wang Q, Liang X, Breyer RM, Montine TJ, Kirkwood A, Andreasson K. Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor. Experimental Neurology. 217: 63-73. PMID 19416671 DOI: 10.1016/J.Expneurol.2009.01.016  0.407
2008 Boric K, Muñoz P, Gallagher M, Kirkwood A. Potential adaptive function for altered long-term potentiation mechanisms in aging hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8034-9. PMID 18685028 DOI: 10.1523/JNEUROSCI.2036-08.2008  0.456
2007 Seol GH, Ziburkus J, Huang S, Song L, Kim IT, Takamiya K, Huganir RL, Lee HK, Kirkwood A. Neuromodulators control the polarity of spike-timing-dependent synaptic plasticity. Neuron. 55: 919-29. PMID 17880895 DOI: 10.1016/J.Neuron.2007.08.013  0.828
2007 Jiang B, Treviño M, Kirkwood A. Sequential development of long-term potentiation and depression in different layers of the mouse visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9648-52. PMID 17804625 DOI: 10.1523/Jneurosci.2655-07.2007  0.492
2007 Seol GH, Ziburkus J, Huang S, Song L, Kim IT, Takamiya K, Huganir RL, Lee HK, Kirkwood A. Neuromodulators Control the Polarity of Spike-Timing-Dependent Synaptic Plasticity (DOI:10.1016/j.neuron.2007.08.013) Neuron. 56: 754. DOI: 10.1016/J.Neuron.2007.11.007  0.499
2007 Kirkwood A. Neuromodulation of cortical synaptic plasticity Monoaminergic Modulation of Cortical Excitability. 209-216. DOI: 10.1007/978-0-387-72256-6_14  0.45
2006 Goel A, Jiang B, Xu LW, Song L, Kirkwood A, Lee HK. Cross-modal regulation of synaptic AMPA receptors in primary sensory cortices by visual experience. Nature Neuroscience. 9: 1001-3. PMID 16819524 DOI: 10.1038/Nn1725  0.821
2005 Choi SY, Chang J, Jiang B, Seol GH, Min SS, Han JS, Shin HS, Gallagher M, Kirkwood A. Multiple receptors coupled to phospholipase C gate long-term depression in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11433-43. PMID 16339037 DOI: 10.1523/Jneurosci.4084-05.2005  0.663
2005 Lee HK, Min SS, Gallagher M, Kirkwood A. NMDA receptor-independent long-term depression correlates with successful aging in rats. Nature Neuroscience. 8: 1657-9. PMID 16286930 DOI: 10.1038/nn1586  0.772
2005 Saura CA, Chen G, Malkani S, Choi SY, Takahashi RH, Zhang D, Gouras GK, Kirkwood A, Morris RG, Shen J. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6755-64. PMID 16033885 DOI: 10.1523/Jneurosci.1247-05.2005  0.545
2005 Jiang B, Huang ZJ, Morales B, Kirkwood A. Maturation of GABAergic transmission and the timing of plasticity in visual cortex. Brain Research. Brain Research Reviews. 50: 126-33. PMID 16024085 DOI: 10.1016/J.Brainresrev.2005.05.007  0.551
2004 Hayashi ML, Choi SY, Rao BS, Jung HY, Lee HK, Zhang D, Chattarji S, Kirkwood A, Tonegawa S. Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice. Neuron. 42: 773-87. PMID 15182717 DOI: 10.1016/j.neuron.2004.05.003  0.843
2004 Saura CA, Choi SY, Beglopoulos V, Malkani S, Zhang D, Shankaranarayana Rao BS, Chattarji S, Kelleher RJ, Kandel ER, Duff K, Kirkwood A, Shen J. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron. 42: 23-36. PMID 15066262 DOI: 10.1016/S0896-6273(04)00182-5  0.672
2004 Saura CA, Choi S, Beglopoulos V, Malkani S, Zhang D, Shankaranarayana Rao B, Chattarji S, Duff K, Kirkwood A, Shen J. P4-311 Memory deficits and neurodegeneration caused by loss of presenilins in the brain Neurobiology of Aging. 25: S564. DOI: 10.1016/S0197-4580(04)81869-4  0.5
2004 Shen J, Saura C, Choi S, Beglopoulos V, Malkani S, Zhang D, Shankaranarayana Rao B, Chattarji S, Kelleher RJ, Kandel ER, Duff K, Kirkwood A. P4-303 Molecular mechanisms underlying memory loss, synaptic plasticity impairment and neuronal degeneration caused by loss of presenilin function in the adult cerebral cortex Neurobiology of Aging. 25: S561. DOI: 10.1016/S0197-4580(04)81861-X  0.627
2004 Saura CA, Chen G, Malkani S, Choi S, Kirkwood A, Morris RG, Shen J. P4-260 Inactivation of PS1/G-secretase in APP transgenic mice rescues associative and working memory but not reference memory deficits Neurobiology of Aging. 25: S549. DOI: 10.1016/S0197-4580(04)81818-9  0.505
2003 Morales B, Rozas C, Pancetti F, Kirkwood A. [Critical period of cortical plasticity]. Revista De Neurologia. 37: 739-43. PMID 14593633  0.305
2003 Gianfranceschi L, Siciliano R, Walls J, Morales B, Kirkwood A, Huang ZJ, Tonegawa S, Maffei L. Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF. Proceedings of the National Academy of Sciences of the United States of America. 100: 12486-91. PMID 14514885 DOI: 10.1073/Pnas.1934836100  0.392
2002 Morales B, Choi SY, Kirkwood A. Dark rearing alters the development of GABAergic transmission in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8084-90. PMID 12223562 DOI: 10.1523/Jneurosci.22-18-08084.2002  0.615
2002 Choi SY, Morales B, Lee HK, Kirkwood A. Absence of long-term depression in the visual cortex of glutamic Acid decarboxylase-65 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5271-6. PMID 12097476 DOI: 10.1523/Jneurosci.22-13-05271.2002  0.833
2001 Yu H, Saura CA, Choi SY, Sun LD, Yang X, Handler M, Kawarabayashi T, Younkin L, Fedeles B, Wilson MA, Younkin S, Kandel ER, Kirkwood A, Shen J. APP processing and synaptic plasticity in presenilin-1 conditional knockout mice. Neuron. 31: 713-26. PMID 11567612 DOI: 10.1016/S0896-6273(01)00417-2  0.652
2001 Rozas C, Frank H, Heynen AJ, Morales B, Bear MF, Kirkwood A. Developmental inhibitory gate controls the relay of activity to the superficial layers of the visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6791-801. PMID 11517267 DOI: 10.1523/Jneurosci.21-17-06791.2001  0.659
2001 Frankland PW, O'Brien C, Ohno M, Kirkwood A, Silva AJ. Alpha-CaMKII-dependent plasticity in the cortex is required for permanent memory. Nature. 411: 309-13. PMID 11357133 DOI: 10.1038/35077089  0.594
2000 Kirkwood A. Serotonergic control of developmental plasticity. Proceedings of the National Academy of Sciences of the United States of America. 97: 1951-2. PMID 10688919 DOI: 10.1073/pnas.070044697  0.519
1999 Huang ZJ, Kirkwood A, Pizzorusso T, Porciatti V, Morales B, Bear MF, Maffei L, Tonegawa S. BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex. Cell. 98: 739-55. PMID 10499792 DOI: 10.1016/S0092-8674(00)81509-3  0.664
1999 Kirkwood A, Rozas C, Kirkwood J, Perez F, Bear MF. Modulation of long-term synaptic depression in visual cortex by acetylcholine and norepinephrine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1599-609. PMID 10024347 DOI: 10.1523/Jneurosci.19-05-01599.1999  0.674
1997 Kirkwood A, Silva A, Bear MF. Age-dependent decrease of synaptic plasticity in the neocortex of alphaCaMKII mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 3380-3. PMID 9096402 DOI: 10.1073/pnas.94.7.3380  0.686
1996 Aizenman CD, Kirkwood A, Bear MF. A current source density analysis of evoked responses in slices of adult rat visual cortex: implications for the regulation of long-term potentiation. Cerebral Cortex (New York, N.Y. : 1991). 6: 751-8. PMID 8922331 DOI: 10.1093/Cercor/6.6.751  0.602
1996 Kirkwood A, Rioult MC, Bear MF. Experience-dependent modification of synaptic plasticity in visual cortex. Nature. 381: 526-8. PMID 8632826 DOI: 10.1038/381526a0  0.727
1995 Kirkwood A, Bear MF. Elementary forms of synaptic plasticity in the visual cortex. Biological Research. 28: 73-80. PMID 8728822  0.711
1995 Kirkwood A, Lee HK, Bear MF. Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience. Nature. 375: 328-31. PMID 7753198 DOI: 10.1038/375328a0  0.723
1994 Kirkwood A, Bear MF. Homosynaptic long-term depression in the visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3404-12. PMID 8182481 DOI: 10.1523/Jneurosci.14-05-03404.1994  0.688
1994 Kirkwood A, Bear MF. Hebbian synapses in visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1634-45. PMID 8126560 DOI: 10.1523/Jneurosci.14-03-01634.1994  0.651
1994 Kirkwood A, Lisman JE. Determinants of single photon response variability. The Journal of General Physiology. 103: 679-90. PMID 8057084  0.415
1993 Bear MF, Kirkwood A. Neocortical long-term potentiation. Current Opinion in Neurobiology. 3: 197-202. PMID 8513232 DOI: 10.1016/0959-4388(93)90210-P  0.686
1993 Kirkwood A, Dudek SM, Gold JT, Aizenman CD, Bear MF. Common forms of synaptic plasticity in the hippocampus and neocortex in vitro. Science (New York, N.Y.). 260: 1518-21. PMID 8502997 DOI: 10.1126/Science.8502997  0.772
1992 Lisman J, Erickson MA, Richard EA, Cote RH, Bacigalupo J, Johnson E, Kirkwood A. Mechanisms of amplification, deactivation, and noise reduction in invertebrate photoreceptors. Society of General Physiologists Series. 47: 175-99. PMID 1369761  0.455
1992 Kirkwood A, Lisman JE. Action potentials produce a long-term enhancement of M-current in frog sympathetic ganglion. Brain Research. 580: 281-7. PMID 1354558 DOI: 10.1016/0006-8993(92)90955-9  0.491
1991 Kirkwood A, Simmons MA, Mather RJ, Lisman J. Muscarinic suppression of the M-current is mediated by a rise in internal Ca2+ concentration. Neuron. 6: 1009-14. PMID 1905146 DOI: 10.1016/0896-6273(91)90240-Z  0.43
1989 Kirkwood A, Weiner D, Lisman JE. An estimate of the number of G regulator proteins activated per excited rhodopsin in living Limulus ventral photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. 86: 3872-6. PMID 2498877  0.447
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