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Michael Stuart Brown

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1985/brown-bio.html
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"Michael Brown"
Bio:

The Nobel Prize in Physiology or Medicine 1985 was awarded jointly to Michael S. Brown and Joseph L. Goldstein "for their discoveries concerning the regulation of cholesterol metabolism"

Mean distance: 13.93 (cluster 32)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Earl R. Stadtman post-doc 1969-1971 NIH

Children

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Jin Ye grad student UT Southwestern (Cell Biology Tree)
Yinxin Zhang grad student
Scott Allen Armstrong grad student 1994 UT Southwestern (Chemistry Tree)
Thomas O. Daniel post-doc Vanderbilt
Joachim Herz post-doc UT Southwestern
Helen Hobbs post-doc UT Southwestern (Microtree)
Arun Radhakrishnan post-doc UT Southwestern (Chemistry Tree)
Monty Krieger post-doc 1977-1981 University of Texas Southwestern Medical School (Chemistry Tree)
Thomas C. Sudhof post-doc 1983-1986 University of Texas Southwestern
Douglas A. Andres post-doc 1990-1993 UT Southwestern (Chemistry Tree)
Xiaodong Wang post-doc 1991-1995 University of Texas Southwestern Medical School (DevTree)
R. Kip Guy post-doc 1996-1998 UT Southwestern (Chemistry Tree)
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Publications

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Tian J, Goldstein JL, Li S, et al. (2024) Phosphorylation of Insig-2 mediates inhibition of fatty acid synthesis by polyunsaturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 121: e2409262121
Brown MS, Goldstein JL. (2024) How the JCI's most-cited paper sparked the field of lipoprotein research. The Journal of Clinical Investigation. 134
Fang F, Goldstein JL, Shi X, et al. (2022) Unexpected role for IGF-1 in starvation: Maintenance of blood glucose. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208855119
Trinh MN, Brown MS, Seemann J, et al. (2022) Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol. Proceedings of the National Academy of Sciences of the United States of America. 119
Kober DL, Radhakrishnan A, Goldstein JL, et al. (2021) Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing. Cell
Trinh MN, Brown MS, Goldstein JL, et al. (2020) Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine. Proceedings of the National Academy of Sciences of the United States of America
Fang F, Shi X, Brown MS, et al. (2019) Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice. Proceedings of the National Academy of Sciences of the United States of America
Trinh MN, Brown MS, Seemann J, et al. (2018) Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1. Elife. 7
Tian J, Wu J, Chen X, et al. (2018) BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver. Elife. 7
Trinh MN, Brown MS, Seemann J, et al. (2018) Author response: Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1 Elife
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