Michael Stuart Brown
Affiliations: | University of Texas Southwestern Medical Center, Dallas, TX, United States |
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1985/brown-bio.htmlGoogle:
"Michael Brown"Bio:
The Nobel Prize in Physiology or Medicine 1985 was awarded jointly to Michael S. Brown and Joseph L. Goldstein "for their discoveries concerning the regulation of cholesterol metabolism"
Mean distance: 13.93 (cluster 32) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Children
Sign in to add traineeJin Ye | grad student | UT Southwestern (Cell Biology Tree) | |
Yinxin Zhang | grad student | ||
Scott Allen Armstrong | grad student | 1994 | UT Southwestern (Chemistry Tree) |
Thomas O. Daniel | post-doc | Vanderbilt | |
Joachim Herz | post-doc | UT Southwestern | |
Helen Hobbs | post-doc | UT Southwestern (Microtree) | |
Arun Radhakrishnan | post-doc | UT Southwestern (Chemistry Tree) | |
Monty Krieger | post-doc | 1977-1981 | University of Texas Southwestern Medical School (Chemistry Tree) |
Thomas C. Sudhof | post-doc | 1983-1986 | University of Texas Southwestern |
Douglas A. Andres | post-doc | 1990-1993 | UT Southwestern (Chemistry Tree) |
Xiaodong Wang | post-doc | 1991-1995 | University of Texas Southwestern Medical School (DevTree) |
R. Kip Guy | post-doc | 1996-1998 | UT Southwestern (Chemistry Tree) |
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Publications
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Tian J, Goldstein JL, Li S, et al. (2024) Phosphorylation of Insig-2 mediates inhibition of fatty acid synthesis by polyunsaturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 121: e2409262121 |
Brown MS, Goldstein JL. (2024) How the JCI's most-cited paper sparked the field of lipoprotein research. The Journal of Clinical Investigation. 134 |
Fang F, Goldstein JL, Shi X, et al. (2022) Unexpected role for IGF-1 in starvation: Maintenance of blood glucose. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208855119 |
Trinh MN, Brown MS, Seemann J, et al. (2022) Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol. Proceedings of the National Academy of Sciences of the United States of America. 119 |
Kober DL, Radhakrishnan A, Goldstein JL, et al. (2021) Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing. Cell |
Trinh MN, Brown MS, Goldstein JL, et al. (2020) Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine. Proceedings of the National Academy of Sciences of the United States of America |
Fang F, Shi X, Brown MS, et al. (2019) Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice. Proceedings of the National Academy of Sciences of the United States of America |
Trinh MN, Brown MS, Seemann J, et al. (2018) Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1. Elife. 7 |
Tian J, Wu J, Chen X, et al. (2018) BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver. Elife. 7 |
Trinh MN, Brown MS, Seemann J, et al. (2018) Author response: Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1 Elife |