Debra A. Schwinn
Affiliations: | University of Washington, Seattle, Seattle, WA |
Area:
molecular pharmacology, alpha 1 adrenergic receptorsGoogle:
"Debra Schwinn"Bio:
Trained with Bob Lefkowitz at Duke University Medical Center 1987-1992
Mean distance: 106866
Cross-listing: Chemistry Tree
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Publications
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| Gradinaru I, Babaeva E, Schwinn DA, et al. (2015) Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway. Plos One. 10: e0142787 |
| Oganesian A, Yarov-Yarovoy V, Parks WC, et al. (2011) Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway. Proceedings of the National Academy of Sciences of the United States of America. 108: 19796-801 |
| von Homeyer P, Schwinn DA. (2011) Pharmacogenomics of β-adrenergic receptor physiology and response to β-blockade. Anesthesia and Analgesia. 113: 1305-18 |
| Lei B, Morris DP, Smith MP, et al. (2009) Lipid rafts constrain basal alpha(1A)-adrenergic receptor signaling by maintaining receptor in an inactive conformation. Cellular Signalling. 21: 1532-9 |
| Schwinn DA, Roehrborn CG. (2008) Alpha1-adrenoceptor subtypes and lower urinary tract symptoms. International Journal of Urology : Official Journal of the Japanese Urological Association. 15: 193-9 |
| Morris DP, Lei B, Wu YX, et al. (2008) The alpha1a-adrenergic receptor occupies membrane rafts with its G protein effectors but internalizes via clathrin-coated pits. The Journal of Biological Chemistry. 283: 2973-85 |
| Stafford-Smith M, Bartz R, Wilson K, et al. (2007) Alpha-adrenergic mRNA subtype expression in the human nasal turbinate. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthã©Sie. 54: 549-55 |
| Michelotti GA, Brinkley DM, Morris DP, et al. (2007) Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1979-93 |
| Schwinn DA. (2007) IL-8 α1-Adrenergic Receptors and LUTS The Japanese Journal of Urology. 98: 61 |
| Schwinn DA, Afshari NA. (2006) alpha(1)-Adrenergic receptor antagonists and the iris: new mechanistic insights into floppy iris syndrome. Survey of Ophthalmology. 51: 501-12 |