Joseph L. Goldstein

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Genetics
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1985/goldstein-bio.html
Google:
"Joseph Goldstein"
Bio:

The Nobel Prize in Physiology or Medicine 1985 was awarded jointly to Michael S. Brown and Joseph L. Goldstein "for their discoveries concerning the regulation of cholesterol metabolism"

Mean distance: 13.91 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree

Children

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Jin Ye grad student UT Southwestern (Cell Biology Tree)
Scott Allen Armstrong grad student 1994 UT Southwestern (Chemistry Tree)
Thomas O. Daniel post-doc Vanderbilt
Joachim Herz post-doc UT Southwestern
Thomas C. Sudhof post-doc UT Southwestern
Monty Krieger post-doc 1977-1981 UT Southwestern (Chemistry Tree)
Douglas A. Andres post-doc 1990-1993 UT Southwestern (Chemistry Tree)
Xiaodong Wang post-doc 1991-1995 UT Southwestern (DevTree)
R. Kip Guy post-doc 1996-1998 UT Southwestern (Chemistry Tree)
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Publications

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Trinh MN, Brown MS, Seemann J, et al. (2018) Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1. Elife. 7
Tian J, Wu J, Chen X, et al. (2018) BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver. Elife. 7
Brown MS, Radhakrishnan A, Goldstein JL. (2017) Retrospective on Cholesterol Homeostasis: The Central Role of Scap. Annual Review of Biochemistry
Gao Y, Zhou Y, Goldstein JL, et al. (2017) Cholesterol-induced conformation changes in the sterol-sensing domain of the scap protein suggest feedback mechanism to control cholesterol synthesis. The Journal of Biological Chemistry
Trinh MN, Lu F, Li X, et al. (2016) Triazoles inhibit cholesterol export from lysosomes by binding to NPC1. Proceedings of the National Academy of Sciences of the United States of America
Goldstein JL. (2016) The Rule of Three for Prizes in Science and the Bold Triptychs of Francis Bacon. Cell
Tian J, Goldstein JL, Brown MS. (2016) Insulin induction of SREBP-1c in rodent liver requires LXRα-C/EBPβ complex. Proceedings of the National Academy of Sciences of the United States of America
Zhang Y, Lee KM, Kinch LN, et al. (2016) Direct Demonstration that Loop1 of Scap Binds to Loop7, a crucial event in cholesterol homeostasis. The Journal of Biological Chemistry
Lu F, Liang Q, Abi-Mosleh L, et al. (2015) Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection. Elife. 4
Goldstein JL. (2015) A Well-Hung Horse: Sired by Knowledge and Imagination. Cell. 162: 1179-82
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