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Adrian R. Krainer

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 
mRNA splicing
"Adrian Krainer"

Developed the first in vitro RNA splicing reactions using HeLa nuclear extract.

Mean distance: 15.14 (cluster 18)


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Oliver I. Fregoso grad student (ID Tree)
Qiang Wu grad student 1994-1998
Javier F. Caceres post-doc CSHL
Michelle L. Hastings post-doc (Anatomy Tree)
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Park S, Brugiolo M, Akerman M, et al. (2019) Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis. Cell Reports. 29: 2672-2688.e7
Arun G, Diermeier S, Akerman M, et al. (2015) Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes & Development
Nomakuchi TT, Rigo F, Aznarez I, et al. (2015) Antisense oligonucleotide-directed inhibition of nonsense-mediated mRNA decay. Nature Biotechnology
Anczuków O, Krainer AR. (2015) The spliceosome, a potential Achilles heel of MYC-driven tumors. Genome Medicine. 7: 107
Guo Y, Xu Q, Canzio D, et al. (2015) CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell. 162: 900-10
Akerman M, Fregoso OI, Das S, et al. (2015) Differential connectivity of splicing activators and repressors to the human spliceosome. Genome Biology. 16: 119
Krainer AR. (2015) Splicing: still so much to learn. Rna (New York, N.Y.). 21: 500-1
Staropoli JF, Li H, Chun SJ, et al. (2015) Rescue of gene-expression changes in an induced mouse model of spinal muscular atrophy by an antisense oligonucleotide that promotes inclusion of SMN2 exon 7. Genomics. 105: 220-8
Xiong HY, Alipanahi B, Lee LJ, et al. (2015) RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. Science (New York, N.Y.). 347: 1254806
Chen HH, Welling M, Bloch DB, et al. (2014) DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 3: 892-904
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