Adrian R. Krainer
Affiliations: | Cold Spring Harbor Laboratory, Cold Spring Harbor, NY |
Area:
mRNA splicingWebsite:
http://www.cshl.edu/Faculty/krainer-adrian-r.htmlGoogle:
"Adrian Krainer"Bio:
Developed the first in vitro RNA splicing reactions using HeLa nuclear extract.
Mean distance: 15.14 (cluster 18) | S | N | B | C | P |
Children
Sign in to add trainee| Oliver I. Fregoso | grad student | (ID Tree) | |
| Qiang Wu | grad student | 1994-1998 | |
| Chaolin Zhang | grad student | 2004-2008 | CSHL |
| Javier F. Caceres | post-doc | CSHL | |
| Michelle L. Hastings | post-doc | (Anatomy Tree) |
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Publications
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| Segovia D, Adams DW, Hoffman N, et al. (2024) SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. Proceedings of the National Academy of Sciences of the United States of America. 121: e2322974121 |
| Jbara A, Lin KT, Stossel C, et al. (2023) RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer. Nature |
| Hastings ML, Krainer AR. (2023) RNA therapeutics. Rna (New York, N.Y.). 29: 393-395 |
| Kim YJ, Nomakuchi T, Papaleonidopoulou F, et al. (2022) Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy. Nature Communications. 13: 2978 |
| Gao Y, Lin KT, Jiang T, et al. (2022) Systematic characterization of short intronic splicing-regulatory elements in SMN2 pre-mRNA. Nucleic Acids Research |
| Kim YJ, Sivetz N, Layne J, et al. (2022) Exon-skipping antisense oligonucleotides for cystic fibrosis therapy. Proceedings of the National Academy of Sciences of the United States of America. 119 |
| Ajiro M, Awaya T, Kim YJ, et al. (2021) Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia. Nature Communications. 12: 4507 |
| Frederiksen SB, Holm LL, Larsen MR, et al. (2020) Identification of SRSF10 as a regulator of SMN2 ISS-N1. Human Mutation |
| Sheng L, Rigo F, Bennett CF, et al. (2020) Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model. Nucleic Acids Research |
| Rahman MA, Lin KT, Bradley RK, et al. (2020) Recurrent SRSF2 mutations in MDS affect both splicing and NMD. Genes & Development |