Mathew M. Blurton-Jones, Ph.D.

Affiliations: 
Neurobiology & Behavior University of California, Irvine, Irvine, CA 
Area:
Alzheimer's disease, Parkinson's disease, stem cells
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"Mathew Blurton-Jones"
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Parents

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Mark Tuszynski grad student 2002 UCSD
 (Estrogen modulates neurotrophin systems in the brain via putative actions on inhibitory neurons.)
Carl W. Cotman post-doc UC Irvine
Frank LaFerla post-doc UC Irvine

Children

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Stephen T. Yeung research assistant UC Irvine (ImmunoTree)
Edsel Abud grad student UC Irvine
Wesley Chen grad student UC Irvine
Morgan A Coburn grad student
Natalie R. S. Goldberg grad student UC Irvine
Samuel E. Marsh grad student 2011-2016 UC Irvine
Alberto Granzotto research scientist UC Irvine
Hayk Davtyan research scientist 2017- UC Irvine
BETA: Related publications

Publications

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Sun GG, Wang C, Mazzarino RC, et al. (2024) Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer's disease. Cell Reports. 43: 114982
Profaci CP, Harvey SS, Bajc K, et al. (2024) Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism. Neuron
Sakthivel PS, Scipioni L, Karam J, et al. (2024) Organelle phenotyping and multi-dimensional microscopy identify C1q as a novel regulator of microglial function. Journal of Neurochemistry
Granzotto A, McQuade A, Chadarevian JP, et al. (2024) ER and SOCE Ca signals are not required for directed cell migration in human iPSC-derived microglia. Cell Calcium. 123: 102923
Rosenzweig N, Kleemann KL, Rust T, et al. (2024) Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nature Medicine
Chadarevian JP, Hasselmann J, Lahian A, et al. (2024) Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy. Neuron
Blurton-Jones M, Spencer B, Michael S, et al. (2024) Correction: Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Research & Therapy. 15: 88
Kang YJ, Hyeon SJ, McQuade A, et al. (2024) Neurotoxic Microglial Activation via IFNγ-Induced Nrf2 Reduction Exacerbating Alzheimer's Disease. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2304357
Granzotto A, McQuade A, Chadarevian JP, et al. (2024) ER and SOCE Ca signals are not required for directed cell migration in human microglia. Biorxiv : the Preprint Server For Biology
Eskandari-Sedighi G, Blurton-Jones M. (2023) Microglial APOE4: more is less and less is more. Molecular Neurodegeneration. 18: 99
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