Eugene O. Major - Publications

National Institutes of Health, Bethesda, MD 

170 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Barreras P, Pamies D, Monaco MC, Muñoz LS, Zhong X, Major EO, Hogberg HT, Hartung T, Pardo CA. A human-derived 3D brain organoid model to study JC virus infection. Journal of Neurovirology. PMID 35239145 DOI: 10.1007/s13365-022-01062-7  0.334
2020 Li GH, Maric D, Major EO, Nath A. Productive HIV infection in astrocytes can be established via a nonclassical mechanism. Aids (London, England). 34: 963-978. PMID 32379159 DOI: 10.1097/Qad.0000000000002512  0.428
2020 Eis PS, Bruno CD, Richmond TA, Koralnik IJ, Hanson BA, Major EO, Chow CR, Hendel-Chavez H, Stankoff B, Gasnault J, Taoufik Y, Hatchwell E. Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy. Frontiers in Neurology. 11: 186. PMID 32256442 DOI: 10.3389/fneur.2020.00186  0.342
2020 Li GH, Maric D, Major EO, Nath A. Productive HIV infection in astrocytes can be established via a non-classical mechanism. Aids (London, England). PMID 32073447 DOI: 10.1097/QAD.0000000000002512  0.319
2020 Ryerson LZ, Major EO. Natalizumab related progressive multifocal leukoencephalopathy Drug Discovery Today: Disease Models. DOI: 10.1016/J.Ddmod.2020.02.002  0.366
2019 Cortese I, Muranski P, Enose-Akahata Y, Ha SK, Smith B, Monaco M, Ryschkewitsch C, Major EO, Ohayon J, Schindler MK, Beck E, Reoma LB, Jacobson S, Reich DS, Nath A. Pembrolizumab Treatment for Progressive Multifocal Leukoencephalopathy. The New England Journal of Medicine. PMID 30969503 DOI: 10.1056/NEJMoa1815039  0.357
2018 Choi EH, Xu Y, Medynets M, Monaco MCG, Major EO, Nath A, Wang T. Activated T cells induce proliferation of oligodendrocyte progenitor cells via release of vascular endothelial cell growth factor-A. Glia. 66: 2503-2513. PMID 30500113 DOI: 10.1002/Glia.23501  0.31
2018 McKenzie BA, Mamik MK, Saito LB, Boghozian R, Monaco MC, Major EO, Lu JQ, Branton WG, Power C. Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29895691 DOI: 10.1073/Pnas.1722041115  0.325
2018 Major EO, Yousry TA, Clifford DB. Pathogenesis of progressive multifocal leukoencephalopathy and risks associated with treatments for multiple sclerosis: a decade of lessons learned. The Lancet. Neurology. 17: 467-480. PMID 29656742 DOI: 10.1016/S1474-4422(18)30040-1  0.378
2016 Soleimani-Meigooni DN, Schwetye KE, Angeles MR, Ryschkewitsch CF, Major EO, Dang X, Koralnik IJ, Schmidt RE, Clifford DB, Kuhlmann FM, Bucelli RC. JC virus granule cell neuronopathy in the setting of chronic lymphopenia treated with recombinant interleukin-7. Journal of Neurovirology. PMID 27421731 DOI: 10.1007/S13365-016-0465-0  0.398
2016 Darbinyan A, Major EO, Morgello S, Holland S, Ryschkewitsch C, Monaco MC, Naidich TP, Bederson J, Malaczynska J, Ye F, Gordon R, Cunningham-Rundles C, Fowkes M, Tsankova NM. BK virus encephalopathy and sclerosing vasculopathy in a patient with hypohidrotic ectodermal dysplasia and immunodeficiency. Acta Neuropathologica Communications. 4: 73. PMID 27411570 DOI: 10.1186/S40478-016-0342-3  0.411
2016 Major EO, Nath A. A link between long-term natalizumab dosing in MS and PML: Putting the puzzle together. Neurology® Neuroimmunology & Neuroinflammation. 3: e235. PMID 27213175 DOI: 10.1212/Nxi.0000000000000235  0.357
2016 Zerbe CS, Marciano BE, Katial RK, Santos CB, Adamo N, Hsu AP, Hanks ME, Darnell DN, Quesado MM, Frein C, Barnhart LA, Anderson VL, Uzel G, Freeman AF, Lisco A, ... ... Major EO, et al. Progressive Multifocal Leukencephalopathy in Primary Immune Deficiencies: STAT1 Gain of Function and Review of the Literature. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 26743090 DOI: 10.1093/Cid/Civ1220  0.354
2015 Li GH, Anderson C, Jaeger L, Do T, Major EO, Nath A. Cell-to-cell contact facilitates HIV transmission from lymphocytes to astrocytes via CXCR4. Aids (London, England). 29: 755-66. PMID 25985398 DOI: 10.1097/Qad.0000000000000605  0.446
2015 Monaco MC, Major EO. Immune System Involvement in the Pathogenesis of JC Virus Induced PML: What is Learned from Studies of Patients with Underlying Diseases and Therapies as Risk Factors. Frontiers in Immunology. 6: 159. PMID 25972864 DOI: 10.3389/fimmu.2015.00159  0.421
2015 Wang T, Choi E, Monaco MC, Major EO, Medynets M, Nath A. Direct induction of human neural stem cells from peripheral blood hematopoietic progenitor cells. Journal of Visualized Experiments : Jove. 52298. PMID 25650990 DOI: 10.3791/52298  0.334
2015 Van Loy T, Thys K, Ryschkewitsch C, Lagatie O, Monaco MC, Major EO, Tritsmans L, Stuyver LJ. JC virus quasispecies analysis reveals a complex viral population underlying progressive multifocal leukoencephalopathy and supports viral dissemination via the hematogenous route. Journal of Virology. 89: 1340-7. PMID 25392214 DOI: 10.1128/JVI.02565-14  0.402
2014 Frohman EM, Douek D, Major EO. Relevance of CD34+ cells as a reservoir for JC virus in patients with multiple sclerosis--reply. Jama Neurology. 71: 1192-3. PMID 25200546 DOI: 10.1001/jamaneurol.2014.1858  0.342
2014 Warnke C, von Geldern G, Markwerth P, Dehmel T, Hoepner R, Gold R, Pawlita M, Kümpfel T, Mäurer M, Stangel M, Wegner F, Hohlfeld R, Straeten V, Limmroth V, Weber T, ... ... Major E, et al. Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy. Annals of Neurology. 76: 792-801. PMID 24729444 DOI: 10.1002/Ana.24153  0.348
2014 Frohman EM, Monaco MC, Remington G, Ryschkewitsch C, Jensen PN, Johnson K, Perkins M, Liebner J, Greenberg B, Monson N, Frohman TC, Douek D, Major EO. JC virus in CD34+ and CD19+ cells in patients with multiple sclerosis treated with natalizumab. Jama Neurology. 71: 596-602. PMID 24664166 DOI: 10.1001/Jamaneurol.2014.63  0.341
2014 Marshall LJ, Ferenczy MW, Daley EL, Jensen PN, Ryschkewitsch CF, Major EO. Lymphocyte gene expression and JC virus noncoding control region sequences are linked with the risk of progressive multifocal leukoencephalopathy. Journal of Virology. 88: 5177-83. PMID 24554653 DOI: 10.1128/Jvi.03221-13  0.324
2013 Wang T, Choi E, Monaco MC, Campanac E, Medynets M, Do T, Rao P, Johnson KR, Elkahloun AG, Von Geldern G, Johnson T, Subramaniam S, Hoffman D, Major E, Nath A. Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation. Plos One. 8: e81720. PMID 24303066 DOI: 10.1371/Journal.Pone.0081720  0.353
2013 Ferenczy MW, Johnson KR, Steinberg SM, Marshall LJ, Monaco MC, Beschloss AM, Jensen PN, Major EO. Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 1303-19. PMID 24052414 DOI: 10.1007/S11481-013-9499-8  0.432
2013 Major EO, Frohman E, Douek D. JC viremia in natalizumab-treated patients with multiple sclerosis. The New England Journal of Medicine. 368: 2240-1. PMID 23738566 DOI: 10.1056/NEJMc1214233  0.406
2013 Ryschkewitsch CF, Jensen PN, Major EO. Multiplex qPCR assay for ultra sensitive detection of JCV DNA with simultaneous identification of genotypes that discriminates non-virulent from virulent variants. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 57: 243-8. PMID 23619054 DOI: 10.1016/j.jcv.2013.03.009  0.336
2013 Ferenczy MW, Johnson KR, Marshall LJ, Monaco MC, Major EO. Differentiation of human fetal multipotential neural progenitor cells to astrocytes reveals susceptibility factors for JC virus. Journal of Virology. 87: 6221-31. PMID 23536657 DOI: 10.1128/Jvi.00396-13  0.478
2013 Brew BJ, McLean CA, Major EO. Progressive multifocal leukoencephalopathy caused by BK virus? The Medical Journal of Australia. 198: 179-80. PMID 23451948 DOI: 10.5694/Mja12.11798  0.364
2013 Havla J, Berthele A, Kümpfel T, Krumbholz M, Jochim A, Kronsbein H, Ryschkewitsch C, Jensen P, Lippmann K, Hemmer B, Major E, Hohlfeld R. Co-occurrence of two cases of progressive multifocal leukoencephalopathy in a natalizumab "infusion group". Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1213-5. PMID 23124790 DOI: 10.1177/1352458512466165  0.341
2012 Monaco MC, Maric D, Bandeian A, Leibovitch E, Yang W, Major EO. Progenitor-derived oligodendrocyte culture system from human fetal brain. Journal of Visualized Experiments : Jove. PMID 23288248 DOI: 10.3791/4274  0.352
2012 Henderson LJ, Sharma A, Monaco MC, Major EO, Al-Harthi L. Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription through its intact core and cysteine-rich domains inhibits Wnt/β-catenin signaling in astrocytes: relevance to HIV neuropathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16306-13. PMID 23152614 DOI: 10.1523/Jneurosci.3145-12.2012  0.37
2012 Perkins MR, Ryschkewitsch C, Liebner JC, Monaco MC, Himelfarb D, Ireland S, Roque A, Edward HL, Jensen PN, Remington G, Abraham T, Abraham J, Greenberg B, Kaufman C, LaGanke C, ... ... Major EO, et al. Changes in JC virus-specific T cell responses during natalizumab treatment and in natalizumab-associated progressive multifocal leukoencephalopathy. Plos Pathogens. 8: e1003014. PMID 23144619 DOI: 10.1371/journal.ppat.1003014  0.343
2012 Ferenczy MW, Marshall LJ, Nelson CD, Atwood WJ, Nath A, Khalili K, Major EO. Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clinical Microbiology Reviews. 25: 471-506. PMID 22763635 DOI: 10.1128/Cmr.05031-11  0.429
2012 Matos A, Duque V, Luxo C, Meliço-Silvestre A, Major EO. Individuals infected with JC polyomavirus do not present detectable JC virus DNA in oropharyngeal fluids. The Journal of General Virology. 93: 692-7. PMID 22158878 DOI: 10.1099/vir.0.036798-0  0.413
2012 Monaco MC, Major EO. The link between VLA-4 and JC virus reactivation. Expert Review of Clinical Immunology. 8: 63-72. PMID 22149341 DOI: 10.1586/eci.11.85  0.448
2012 Marshall LJ, Moore LD, Mirsky MM, Major EO. JC virus promoter/enhancers contain TATA box-associated Spi-B-binding sites that support early viral gene expression in primary astrocytes. The Journal of General Virology. 93: 651-61. PMID 22071512 DOI: 10.1099/vir.0.035832-0  0.4
2011 Kuhle J, Gosert R, Bühler R, Derfuss T, Sutter R, Yaldizli O, Radue EW, Ryschkewitsch C, Major EO, Kappos L, Frank S, Hirsch HH. Management and outcome of CSF-JC virus PCR-negative PML in a natalizumab-treated patient with MS. Neurology. 77: 2010-6. PMID 22076540 DOI: 10.1212/WNL.0b013e31823b9b27  0.33
2011 Tan IL, McArthur JC, Clifford DB, Major EO, Nath A. Immune reconstitution inflammatory syndrome in natalizumab-associated PML. Neurology. 77: 1061-7. PMID 21832229 DOI: 10.1212/WNL.0b013e31822e55e7  0.303
2011 Li W, Henderson LJ, Major EO, Al-Harthi L. IFN-gamma mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the beta-catenin pathway (DKK1) in a STAT 3-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 186: 6771-8. PMID 21562161 DOI: 10.4049/Jimmunol.1100099  0.41
2011 Gosert R, Rinaldo CH, Wernli M, Major EO, Hirsch HH. CMX001 (1-O-hexadecyloxypropyl-cidofovir) inhibits polyomavirus JC replication in human brain progenitor-derived astrocytes. Antimicrobial Agents and Chemotherapy. 55: 2129-36. PMID 21402853 DOI: 10.1128/AAC.00046-11  0.37
2011 Major EO, Ryschkewitsch CF, Jensen PN, Monaco MC. Reply: To PMID 21246607. Annals of Neurology. 69: 430-1. PMID 21387394 DOI: 10.1002/ana.22364  0.322
2011 Eugenin EA, King JE, Hazleton JE, Major EO, Bennett MV, Zukin RS, Berman JW. Differences in NMDA receptor expression during human development determine the response of neurons to HIV-tat-mediated neurotoxicity. Neurotoxicity Research. 19: 138-48. PMID 20094923 DOI: 10.1007/S12640-010-9150-X  0.389
2010 Marshall LJ, Dunham L, Major EO. Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activity. The Journal of General Virology. 91: 3042-52. PMID 20826618 DOI: 10.1099/vir.0.023184-0  0.401
2010 Jiang ZG, Cohen J, Marshall LJ, Major EO. Hexadecyloxypropyl-cidofovir (CMX001) suppresses JC virus replication in human fetal brain SVG cell cultures. Antimicrobial Agents and Chemotherapy. 54: 4723-32. PMID 20823288 DOI: 10.1128/Aac.00837-10  0.457
2010 Ryschkewitsch CF, Jensen PN, Monaco MC, Major EO. JC virus persistence following progressive multifocal leukoencephalopathy in multiple sclerosis patients treated with natalizumab. Annals of Neurology. 68: 384-91. PMID 20818792 DOI: 10.1002/ana.22137  0.336
2010 Gosert R, Kardas P, Major EO, Hirsch HH. Rearranged JC virus noncoding control regions found in progressive multifocal leukoencephalopathy patient samples increase virus early gene expression and replication rate. Journal of Virology. 84: 10448-56. PMID 20686041 DOI: 10.1128/JVI.00614-10  0.448
2010 Marshall LJ, Major EO. Molecular regulation of JC virus tropism: insights into potential therapeutic targets for progressive multifocal leukoencephalopathy. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 404-17. PMID 20401541 DOI: 10.1007/s11481-010-9203-1  0.45
2010 Matos A, Duque V, Beato S, da Silva JP, Major E, Meliço-Silvestre A. Characterization of JC human polyomavirus infection in a Portuguese population. Journal of Medical Virology. 82: 494-504. PMID 20087944 DOI: 10.1002/jmv.21710  0.422
2010 Major EO. Progressive multifocal leukoencephalopathy in patients on immunomodulatory therapies. Annual Review of Medicine. 61: 35-47. PMID 19719397 DOI: 10.1146/  0.427
2009 Berger JR, Houff SA, Major EO. Monoclonal antibodies and progressive multifocal leukoencephalopathy. Mabs. 1: 583-9. PMID 20073129 DOI: 10.4161/mabs.1.6.9884  0.356
2009 LindÃ¥ H, von Heijne A, Major EO, Ryschkewitsch C, Berg J, Olsson T, Martin C. Progressive multifocal leukoencephalopathy after natalizumab monotherapy. The New England Journal of Medicine. 361: 1081-7. PMID 19741229 DOI: 10.1056/NEJMoa0810316  0.355
2009 Carson KR, Focosi D, Major EO, Petrini M, Richey EA, West DP, Bennett CL. Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project. The Lancet. Oncology. 10: 816-24. PMID 19647202 DOI: 10.1016/S1470-2045(09)70161-5  0.368
2009 Lamba S, Ravichandran V, Major EO. Glial cell type-specific subcellular localization of 14-3-3 zeta: an implication for JCV tropism. Glia. 57: 971-7. PMID 19062179 DOI: 10.1002/glia.20821  0.44
2009 Bachis A, Biggio F, Major EO, Mocchetti I. M- and T-tropic HIVs promote apoptosis in rat neurons. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 150-60. PMID 19034668 DOI: 10.1007/S11481-008-9141-3  0.403
2009 Iacobaeus E, Ryschkewitsch C, Gravell M, Khademi M, Wallstrom E, Olsson T, Brundin L, Major EO. Analysis of cerebrospinal fluid and cerebrospinal fluid cells from patients with multiple sclerosis for detection of JC virus DNA Multiple Sclerosis. 15: 28-35. PMID 18805840 DOI: 10.1177/1352458508096870  0.345
2008 Landry ML, Eid T, Bannykh S, Major E. False negative PCR despite high levels of JC virus DNA in spinal fluid: Implications for diagnostic testing. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 43: 247-9. PMID 18701345 DOI: 10.1016/j.jcv.2008.07.003  0.336
2008 Bohl DL, Brennan DC, Ryschkewitsch C, Gaudreault-Keener M, Major EO, Storch GA. BK virus antibody titers and intensity of infections after renal transplantation. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 43: 184-9. PMID 18676176 DOI: 10.1016/j.jcv.2008.06.009  0.328
2008 Ravichandran V, Major EO. DNA-binding transcription factor NF-1A negatively regulates JC virus multiplication. The Journal of General Virology. 89: 1396-401. PMID 18474555 DOI: 10.1099/vir.0.2008/000059-0  0.352
2007 Houff SA, Major EO. Neuropharmacology of HIV/AIDS. Handbook of Clinical Neurology. 85: 319-64. PMID 18808990 DOI: 10.1016/S0072-9752(07)85019-6  0.369
2007 Schwartz L, Civitello L, Dunn-Pirio A, Ryschkewitsch S, Berry E, Cavert W, Kinzel N, Lawrence DM, Hazra R, Major EO. Evidence of human immunodeficiency virus type 1 infection of nestin-positive neural progenitors in archival pediatric brain tissue. Journal of Neurovirology. 13: 274-83. PMID 17613718 DOI: 10.1080/13550280701344975  0.468
2007 Ravichandran V, Jensen PN, Major EO. MEK1/2 inhibitors block basal and transforming growth factor 1beta1-stimulated JC virus multiplication. Journal of Virology. 81: 6412-8. PMID 17409139 DOI: 10.1128/JVI.02658-06  0.342
2007 Roseti L, Facchini A, De Franceschi L, Marconi E, Major EO, Grigolo B. Induction of original phenotype of human immortalized chondrocytes: a quantitative gene expression analysis. International Journal of Molecular Medicine. 19: 89-96. PMID 17143552 DOI: 10.3892/Ijmm.19.1.89  0.302
2006 Berman JW, Carson MJ, Chang L, Cox BM, Fox HS, Gonzalez RG, Hanson GR, Hauser KF, Ho WZ, Hong JS, Major EO, Maragos WF, Masliah E, McArthur JC, Miller DB, et al. NeuroAIDS, drug abuse, and inflammation: building collaborative research activities. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 351-99. PMID 18040811 DOI: 10.1007/S11481-006-9048-9  0.391
2006 Ahlqvist J, Donati D, Martinelli E, Akhyani N, Hou J, Major EO, Jacobson S, Fogdell-Hahn A. Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A in astrocytes and in T-cells. Journal of Medical Virology. 78: 1542-53. PMID 17063514 DOI: 10.1002/Jmv.20737  0.36
2006 Ravichandran V, Major EO. Viral proteomics: a promising approach for understanding JC virus tropism. Proteomics. 6: 5628-36. PMID 16991198 DOI: 10.1002/pmic.200600261  0.359
2006 Li J, Melenhorst J, Hensel N, Rezvani K, Sconocchia G, Kilical Y, Hou J, Curfman B, Major E, Barrett AJ. T-cell responses to peptide fragments of the BK virus T antigen: implications for cross-reactivity of immune response to JC virus. The Journal of General Virology. 87: 2951-60. PMID 16963754 DOI: 10.1099/vir.0.82094-0  0.321
2006 Ravichandran V, Sabath BF, Jensen PN, Houff SA, Major EO. Interactions between c-Jun, nuclear factor 1, and JC virus promoter sequences: implications for viral tropism. Journal of Virology. 80: 10506-13. PMID 16928756 DOI: 10.1128/JVI.01355-06  0.324
2006 Schwartz L, Major EO. Neural progenitors and HIV-1-associated central nervous system disease in adults and children. Current Hiv Research. 4: 319-27. PMID 16842084 DOI: 10.2174/157016206777709438  0.42
2006 Nath A, Venkataramana A, Reich DS, Cortese I, Major EO. Progression of progressive multifocal leukoencephalopathy despite treatment with β-interferon Neurology. 66: 149-150. PMID 16769975 DOI: 10.1212/01.Wnl.0000230563.29202.6A  0.339
2006 Hou J, Seth P, Major EO. JC virus can infect human immune and nervous system progenitor cells: implications for pathogenesis. Advances in Experimental Medicine and Biology. 577: 266-73. PMID 16626042 DOI: 10.1007/0-387-32957-9_19  0.445
2006 Yousry TA, Major EO, Ryschkewitsch C, Fahle G, Fischer S, Hou J, Curfman B, Miszkiel K, Mueller-Lenke N, Sanchez E, Barkhof F, Radue EW, Jäger HR, Clifford DB. Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. The New England Journal of Medicine. 354: 924-33. PMID 16510746 DOI: 10.1056/Nejmoa054693  0.328
2006 Lubensky IA, Vortmeyer AO, Kim S, Lonser RR, Park DM, Ikejiri B, Li J, Okamoto H, Walbridge S, Ryschkewitsch C, Major E, Oldfield EH, Zhuang Z. Identification of tumor precursor cells in the brains of primates with radiation-induced de novo glioblastoma multiforme. Cell Cycle (Georgetown, Tex.). 5: 452-6. PMID 16479164 DOI: 10.4161/Cc.5.4.2482  0.305
2006 Lawrence DM, Seth P, Durham L, Diaz F, Boursiquot R, Ransohoff RM, Major EO. Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein-1 in cultured human brain-derived progenitor cells. Glia. 53: 81-91. PMID 16206198 DOI: 10.1002/glia.20261  0.448
2006 Sabri F, Chiodi F, Piret J, Wei C, Major E, Westermark B, Masucci MG, Levitsky V. Soluble factors released by virus specific activated cytotoxic T-lymphocytes induce apoptotic death of astroglioma cell lines. Brain Pathology. 13: 165-175. PMID 12744470 DOI: 10.1111/J.1750-3639.2003.Tb00016.X  0.328
2006 Ahlqvist J, Donati D, Martinelli E, Akhyani N, Hou J, Major EO, Jacobson S, Fogdell-Hahn A. 4: Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A (HHV-6A) in astrocytes and in T-cells Journal of Clinical Virology. 37. DOI: 10.1016/S1386-6532(06)70023-3  0.335
2005 Seth P, Major EO. Human brain derived cell culture models of HIV-1 infection. Neurotoxicity Research. 8: 83-9. PMID 16260387 DOI: 10.1007/BF03033821  0.47
2005 Hou J, Major E. Management of infections by the human polyomavirus JC: Past, present and future Expert Review of Anti-Infective Therapy. 3: 629-640. PMID 16107201 DOI: 10.1586/14787210.3.4.629  0.407
2005 Donati D, Martinelli E, Cassiani-Ingoni R, Ahlqvist J, Hou J, Major EO, Jacobson S. Variant-specific tropism of human herpesvirus 6 in human astrocytes. Journal of Virology. 79: 9439-48. PMID 16014907 DOI: 10.1128/JVI.79.15.9439-9448.2005  0.435
2005 Nicola AV, Hou J, Major EO, Straus SE. Herpes simplex virus type 1 enters human epidermal keratinocytes, but not neurons, via a pH-dependent endocytic pathway. Journal of Virology. 79: 7609-16. PMID 15919913 DOI: 10.1128/JVI.79.12.7609-7616.2005  0.38
2005 Rollison DE, Utaipat U, Ryschkewitsch C, Hou J, Goldthwaite P, Daniel R, Helzlsouer KJ, Burger PC, Shah KV, Major EO. Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories. International Journal of Cancer. Journal International Du Cancer. 113: 769-74. PMID 15499616 DOI: 10.1002/Ijc.20641  0.319
2004 Royal W, Leander M, Chen YE, Major EO, Bissonnette RP. Nuclear receptor activation and interaction with morphine. Journal of Neuroimmunology. 157: 61-5. PMID 15579281 DOI: 10.1016/j.jneuroim.2004.08.023  0.326
2004 Janabi N, Jensen PN, Major EO. Differential effects of interferon-gamma on the expression of cyclooxygenase-2 in high-grade human gliomas versus primary astrocytes. Journal of Neuroimmunology. 156: 113-22. PMID 15465602 DOI: 10.1016/j.jneuroim.2004.07.012  0.351
2004 Ryschkewitsch C, Jensen P, Hou J, Fahle G, Fischer S, Major EO. Comparison of PCR-southern hybridization and quantitative real-time PCR for the detection of JC and BK viral nucleotide sequences in urine and cerebrospinal fluid. Journal of Virological Methods. 121: 217-21. PMID 15381359 DOI: 10.1016/j.jviromet.2004.06.021  0.32
2004 Lawrence DM, Durham LC, Schwartz L, Seth P, Maric D, Major EO. Human immunodeficiency virus type 1 infection of human brain-derived progenitor cells. Journal of Virology. 78: 7319-28. PMID 15220405 DOI: 10.1128/JVI.78.14.7319-7328.2004  0.499
2004 Seth P, Diaz F, Tao-Cheng JH, Major EO. JC virus induces nonapoptotic cell death of human central nervous system progenitor cell-derived astrocytes. Journal of Virology. 78: 4884-91. PMID 15078969 DOI: 10.1128/JVI.78.9.4884-4891.2004  0.407
2004 Buch S, Sui Y, Potula R, Pinson D, Adany I, Li Z, Huang M, Li S, Dhillon N, Major E, Narayan O. Role of interleukin-4 and monocyte chemoattractant protein-1 in the neuropathogenesis of X4 simian human immunodeficiency virus infection in macaques. Journal of Neurovirology. 10: 118-24. PMID 14982750 DOI: 10.1080/753312763  0.428
2003 D'Costa J, Harvey-White J, Qasba P, Limaye A, Kaneski CR, Davis-Warren A, Brady RO, Bankiewicz KS, Major EO, Arya SK. HIV-2 derived lentiviral vectors: gene transfer in Parkinson's and Fabry disease models in vitro. Journal of Medical Virology. 71: 173-82. PMID 12938190 DOI: 10.1002/Jmv.10467  0.362
2003 Bofill-Mas S, Clemente-Casares P, Major EO, Curfman B, Girones R. Analysis of the excreted JC virus strains and their potential oral transmission. Journal of Neurovirology. 9: 498-507. PMID 12907394 DOI: 10.1080/13550280390218887  0.376
2003 Messam CA, Hou J, Gronostajski RM, Major EO. Lineage pathway of human brain progenitor cells identified by JC virus susceptibility. Annals of Neurology. 53: 636-46. PMID 12730998 DOI: 10.1002/Ana.10523  0.455
2003 Joseph J, Major EO. Basic, clinical, and epidemiological studies of progressive multifocal leukoencephalopathy: implications for therapy. Journal of Neurovirology. 9: 1-2. PMID 12709863 DOI: 10.1080/13550280390195414  0.406
2003 Seth P, Diaz F, Major EO. Advances in the biology of JC virus and induction of progressive multifocal leukoencephalopathy. Journal of Neurovirology. 9: 236-46. PMID 12707854 DOI: 10.1080/13550280390194019  0.351
2003 Viscidi RP, Rollison DE, Viscidi E, Clayman B, Rubalcaba E, Daniel R, Major EO, Shah KV. Serological cross-reactivities between antibodies to simian virus 40, BK virus, and JC virus assessed by virus-like-particle-based enzyme immunoassays. Clinical and Diagnostic Laboratory Immunology. 10: 278-85. PMID 12626455 DOI: 10.1128/CDLI.10.2.278-285.2003  0.34
2003 Chauhan A, Turchan J, Pocernich C, Bruce-Keller A, Roth S, Butterfield DA, Major EO, Nath A. Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport. The Journal of Biological Chemistry. 278: 13512-9. PMID 12551932 DOI: 10.1074/Jbc.M209381200  0.344
2002 Grigolo B, Roseti L, Neri S, Gobbi P, Jensen P, Major EO, Facchini A. Human articular chondrocytes immortalized by HPV-16 E6 and E7 genes: Maintenance of differentiated phenotype under defined culture conditions. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 10: 879-89. PMID 12435333 DOI: 10.1053/joca.2002.0836  0.327
2002 Sabath BF, Major EO. Traffic of JC virus from sites of initial infection to the brain: the path to progressive multifocal leukoencephalopathy. The Journal of Infectious Diseases. 186: S180-6. PMID 12424695 DOI: 10.1086/344280  0.452
2002 Hicks A, Potula R, Sui YJ, Villinger F, Pinson D, Adany I, Li Z, Long C, Cheney P, Marcario J, Novembre F, Mueller N, Kumar A, Major E, Narayan O, et al. Neuropathogenesis of lentiviral infection in macaques: roles of CXCR4 and CCR5 viruses and interleukin-4 in enhancing monocyte chemoattractant protein-1 production in macrophages. The American Journal of Pathology. 161: 813-22. PMID 12213709 DOI: 10.1016/S0002-9440(10)64241-1  0.421
2002 Messam CA, Hou J, Berman JW, Major EO. Analysis of the temporal expression of nestin in human fetal brain derived neuronal and glial progenitor cells. Brain Research. Developmental Brain Research. 134: 87-92. PMID 11947939 DOI: 10.1016/S0165-3806(01)00325-X  0.332
2002 Lawrence DM, Major EO. HIV-1 and the brain: connections between HIV-1-associated dementia, neuropathology and neuroimmunology. Microbes and Infection / Institut Pasteur. 4: 301-8. PMID 11909740 DOI: 10.1016/S1286-4579(02)01542-3  0.382
2002 Peterson P, Major E, Oldstone M, Remington J. Immunopathogenesis of Infections and Inflammatory Diseases of the Brain The Journal of Infectious Diseases. 186: i-i. DOI: 10.1086/512577  0.339
2001 Bankiewicz KS, Pivirotto P, Sanchez-Pernaute R, Major EO. Grafting genetically engineered cells into the striatum of nonhuman primates. Methods in Molecular Medicine. 62: 269-78. PMID 21318782 DOI: 10.1385/1-59259-142-6:269  0.319
2001 Hou J, Major EO. Direct and indirect mechanisms of HIV-1 neuropathogenesis in the human central nervous system. Advances in Experimental Medicine and Biology. 493: 29-34. PMID 11727777 DOI: 10.1007/0-306-47611-8_3  0.443
2001 Monaco MC, Sabath BF, Durham LC, Major EO. JC virus multiplication in human hematopoietic progenitor cells requires the NF-1 class D transcription factor. Journal of Virology. 75: 9687-95. PMID 11559801 DOI: 10.1128/JVI.75.20.9687-9695.2001  0.413
2001 Levy RM, Major E, Ali MJ, Cohen B, Groothius D. Convection-enhanced intraparenchymal delivery (CEID) of cytosine arabinoside (AraC) for the treatment of HIV-related progressive multifocal leukoencephalopathy (PML) Journal of Neurovirology. 7: 382-385. PMID 11517421 DOI: 10.1080/13550280152537283  0.375
2001 Jensen PN, Major EO. A classification scheme for human polyomavirus JCV variants based on the nucleotide sequence of the noncoding regulatory region. Journal of Neurovirology. 7: 280-7. PMID 11517403 DOI: 10.1080/13550280152537102  0.308
2001 Clifford DB, Major EO. The biology of JC virus and progressive multifocal leukoencephalopathy Journal of Neurovirology. 7: 279. PMID 11517402 DOI: 10.1080/13550280152537094  0.365
2000 Messam CA, Major EO. Stages of restricted HIV-1 infection in astrocyte cultures derived from human fetal brain tissue. Journal of Neurovirology. 6: S90-4. PMID 10871771  0.367
2000 Wu DT, Woodman SE, Weiss JM, McManus CM, D'Aversa TG, Hesselgesser J, Major EO, Nath A, Berman JW. Mechanisms of leukocyte trafficking into the CNS. Journal of Neurovirology. 6: S82-5. PMID 10871769  0.348
2000 Major EO, Rausch D, Marra C, Clifford D. HIV-associated dementia. Science (New York, N.Y.). 288: 440-2. PMID 10798979 DOI: 10.1126/Science.288.5465.439D  0.324
2000 Messam CA, Hou J, Major EO. Coexpression of nestin in neural and glial cells in the developing human CNS defined by a human-specific anti-nestin antibody. Experimental Neurology. 161: 585-96. PMID 10686078 DOI: 10.1006/exnr.1999.7319  0.359
1999 Berger JR, Major EO. Progressive multifocal leukoencephalopathy. Seminars in Neurology. 19: 193-200. PMID 10718540 DOI: 10.1055/s-2008-1040837  0.388
1999 Sabri F, Tresoldi E, Stefano MD, Polo S, Monaco MC, Verani A, Fiore JR, Lusso P, Major E, Chiodi F, Scarlatti G. Nonproductive human immunodeficiency virus type 1 infection of human fetal astrocytes: independence from CD4 and major chemokine receptors. Virology. 264: 370-384. PMID 10562499 DOI: 10.1006/Viro.1999.9998  0.465
1999 Weiss JM, Nath A, Major EO, Berman JW. HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes. Journal of Immunology (Baltimore, Md. : 1950). 163: 2953-9. PMID 10453044  0.328
1999 Yiannoutsos CT, Major EO, Curfman B, Jensen PN, Gravell M, Hou J, Clifford DB, Hall CD. Relation of JC virus DNA in the cerebrospinal fluid to survival in acquired immunodeficiency syndrome patients with biopsy-proven progressive multifocal leukoencephalopathy. Annals of Neurology. 45: 816-21. PMID 10360779 DOI: 10.1002/1531-8249(199906)45:6<816::AID-ANA21>3.0.CO;2-W  0.328
1999 Nath A, Conant K, Chen P, Scott C, Major EO. Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon. The Journal of Biological Chemistry. 274: 17098-102. PMID 10358063 DOI: 10.1074/Jbc.274.24.17098  0.614
1999 Jensen PN, Major EO. Viral variant nucleotide sequences help expose leukocytic positioning in the JC virus pathway to the CNS. Journal of Leukocyte Biology. 65: 428-38. PMID 10204570 DOI: 10.1002/Jlb.65.4.428  0.429
1998 Major EO, Neel JV. The JC and BK human polyoma viruses appear to be recent introductions to some South American Indian tribes: there is no serological evidence of cross-reactivity with the simian polyoma virus SV40. Proceedings of the National Academy of Sciences of the United States of America. 95: 15525-30. PMID 9861002 DOI: 10.1073/Pnas.95.26.15525  0.358
1998 Monaco MC, Jensen PN, Hou J, Durham LC, Major EO. Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection. Journal of Virology. 72: 9918-23. PMID 9811728 DOI: 10.1128/Jvi.72.12.9918-9923.1998  0.381
1998 Monaco MC, Shin J, Major EO. JC virus infection in cells from lymphoid tissue. Developments in Biological Standardization. 94: 115-22. PMID 9776232  0.34
1998 Hou J, Major EO. The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cell line. Journal of Neurovirology. 4: 451-6. PMID 9718138 DOI: 10.3109/13550289809114545  0.442
1998 Conant K, Ahmed U, Schwartz JP, Major EO. IFN-gamma inhibits AP-1 binding activity in human brain-derived cells through a nitric oxide dependent mechanism. Journal of Neuroimmunology. 88: 39-44. PMID 9688322 DOI: 10.1016/S0165-5728(98)00069-1  0.599
1998 Hall CD, Dafni U, Simpson D, Clifford D, Wetherill PE, Cohen B, McArthur J, Hollander H, Yainnoutsos C, Major E, Millar L, Timpone J. Failure of cytarabine in progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. AIDS Clinical Trials Group 243 Team. The New England Journal of Medicine. 338: 1345-51. PMID 9571254 DOI: 10.1056/Nejm199805073381903  0.369
1998 Conant K, Garzino-Demo A, Nath A, McArthur JC, Halliday W, Power C, Gallo RC, Major EO. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 3117-21. PMID 9501225 DOI: 10.1073/Pnas.95.6.3117  0.644
1997 Weber T, Major EO. Progressive multifocal leukoencephalopathy: molecular biology, pathogenesis and clinical impact. Intervirology. 40: 98-111. PMID 9450227 DOI: 10.1159/000150537  0.427
1997 Gallia GL, Houff SA, Major EO, Khalili K. Review: JC virus infection of lymphocytes--revisited. The Journal of Infectious Diseases. 176: 1603-9. PMID 9395374  0.363
1997 Heyes MP, Chen CY, Major EO, Saito K. Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types. The Biochemical Journal. 326: 351-6. PMID 9291104 DOI: 10.1042/Bj3260351  0.335
1997 Shinohara T, Nagashima K, Major EO. Propagation of the human polyomavirus, JCV, in human neuroblastoma cell lines. Virology. 228: 269-77. PMID 9123834 DOI: 10.1006/Viro.1996.8409  0.404
1996 Dayton ET, Major EO. Recombinant human interleukin 1 beta induces production of prostaglandins in primary human fetal astrocytes and immortalized human fetal astrocyte cultures. Journal of Neuroimmunology. 71: 11-8. PMID 8982097 DOI: 10.1016/S0165-5728(96)00111-7  0.303
1996 Heyes MP, Achim CL, Wiley CA, Major EO, Saito K, Markey SP. Human microglia convert l-tryptophan into the neurotoxin quinolinic acid. The Biochemical Journal. 320: 595-7. PMID 8973572 DOI: 10.1042/Bj3200595  0.306
1996 Sumner C, Shinohara T, Durham L, Traub R, Major EO, Amemiya K. Expression of multiple classes of the nuclear factor-1 family in the developing human brain: differential expression of two classes of NF-1 genes. Journal of Neurovirology. 2: 87-100. PMID 8799200 DOI: 10.3109/13550289609146542  0.358
1996 Monaco MC, Atwood WJ, Gravell M, Tornatore CS, Major EO. JC virus infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: implications for viral latency. Journal of Virology. 70: 7004-12. PMID 8794345 DOI: 10.1128/Jvi.70.10.7004-7012.1996  0.45
1996 Tornatore C, Baker-Cairns B, Yadid G, Hamilton R, Meyers K, Atwood W, Cummins A, Tanner V, Major E. Expression of tyrosine hydroxylase in an immortalized human fetal astrocyte cell line; in vitro characterization and engraftment into the rodent striatum Cell Transplantation. 5: 145-163. PMID 8689028 DOI: 10.1016/0963-6897(95)02041-1  0.336
1996 Conant K, Ma M, Nath A, Major EO. Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes. Journal of Virology. 70: 1384-9. PMID 8627654 DOI: 10.1128/Jvi.70.3.1384-1389.1996  0.671
1996 Neel JV, Major EO, Awa AA, Glover T, Burgess A, Traub R, Curfman B, Satoh C. Hypothesis: "Rogue cell"-type chromosomal damage in lymphocytes is associated with infection with the JC human polyoma virus and has implications for oncopenesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 2690-5. PMID 8610102 DOI: 10.1073/Pnas.93.7.2690  0.436
1995 Atwood WJ, Wang L, Durham LC, Amemiya K, Traub RG, Major EO. Evaluation of the role of cytokine activation in the multiplication of JC virus (JCV) in human fetal glial cells. Journal of Neurovirology. 1: 40-9. PMID 9222341 DOI: 10.3109/13550289509111009  0.447
1995 Major EO, Ault GS. Progressive multifocal leukoencephalopathy: clinical and laboratory observations on a viral induced demyelinating disease in the immunodeficient patient. Current Opinion in Neurology. 8: 184-90. PMID 7551117  0.301
1995 Tomatore C, Conant K, Atwood W, Major E. Characterization of the natural history of HIV-1 infection of astrocytes in the developing pediatric nervous system Journal of Neuroimmunology. 63: 99. DOI: 10.1016/0165-5728(96)80982-9  0.656
1994 Tornatore C, Meyers K, Atwood W, Conant K, Major E. Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes. Journal of Virology. 68: 93-102. PMID 8254781 DOI: 10.1128/Jvi.68.1.93-102.1994  0.696
1994 Tornatore C, Chandra R, Berger JR, Major EO. HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology. 44: 481-7. PMID 8145919 DOI: 10.1212/Wnl.44.3_Part_1.481  0.443
1994 Conant K, Atwood WJ, Traub R, Tornatore C, Major EO. An increase in p50/p65 NF-kB binding to the HIV-1 LTR is not sufficient to increase viral expression in the primary human astrocyte. Virology. 205: 586-90. PMID 7975262 DOI: 10.1006/Viro.1994.1685  0.652
1994 Kennedy PG, Major EO, Williams RK, Straus SE. Down-regulation of glial fibrillary acidic protein expression during acute lytic varicella-zoster virus infection of cultured human astrocytes. Virology. 205: 558-62. PMID 7975257 DOI: 10.1006/viro.1994.1679  0.457
1994 Conant K, Tornatore C, Atwood W, Meyers K, Traub R, Major EO. In vivo and in vitro infection of the astrocyte by HIV-1. Advances in Neuroimmunology. 4: 287-9. PMID 7874397 DOI: 10.1016/S0960-5428(06)80269-X  0.654
1994 Atwood WJ, Tornatore CS, Traub R, Conant K, Drew PD, Major EO. Stimulation of HIV type 1 gene expression and induction of NF-kappa B (p50/p65)-binding activity in tumor necrosis factor alpha-treated human fetal glial cells. Aids Research and Human Retroviruses. 10: 1207-11. PMID 7848678 DOI: 10.1089/Aid.1994.10.1207  0.662
1994 Tornatore C, Amemiya K, Atwood W, Conant K, Major EO, Berger J. JC virus: Current concepts and controversies in the molecular virology and pathogenesis of progressive multifocal leucoencephalopathy Reviews in Medical Virology. 4: 197-219. DOI: 10.1002/rmv.1980040306  0.616
1993 Heyes MP, Saito K, Major EO, Milstien S, Markey SP, Vickers JH. A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate. Brain : a Journal of Neurology. 116: 1425-50. PMID 8293279 DOI: 10.1093/Brain/116.6.1425  0.307
1993 Atwood WJ, Berger JR, Kaderman R, Tornatore CS, Major EO. Human immunodeficiency virus type 1 infection of the brain. Clinical Microbiology Reviews. 6: 339-66. PMID 8269391 DOI: 10.1128/Cmr.6.4.339  0.448
1993 Atwood WJ, Tornatore CS, Meyers K, Major EO. HIV-1 mRNA transcripts from persistently infected human fetal astrocytes. Annals of the New York Academy of Sciences. 693: 324-5. PMID 8267293 DOI: 10.1111/J.1749-6632.1993.Tb26298.X  0.406
1992 Buckle GJ, Godec MS, Rubi JU, Tornatore C, Major EO, Gibbs CJ, Gajdusek DC, Asher DM. Lack of JC viral genomic sequences in multiple sclerosis brain tissue by polymerase chain reaction. Annals of Neurology. 32: 829-31. PMID 1335225 DOI: 10.1002/ana.410320622  0.33
1992 Atwood WJ, Amemiya K, Traub R, Harms J, Major EO. Interaction of the human polyomavirus, JCV, with human B-lymphocytes. Virology. 190: 716-23. PMID 1325703 DOI: 10.1016/0042-6822(92)90909-9  0.438
1992 Tornatore C, Berger JR, Houff SA, Curfman B, Meyers K, Winfield D, Major EO. Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy. Annals of Neurology. 31: 454-62. PMID 1316734 DOI: 10.1002/ana.410310426  0.406
1992 Berger JR, Tornatore C, Major EO, Bruce J, Shapshak P, Yoshioka M, Houff S, Sheremata W, Horton GF, Landy H. Relapsing and remitting human immunodeficiency virus-associated leukoencephalomyelopathy. Annals of Neurology. 31: 34-8. PMID 1311910 DOI: 10.1002/Ana.410310107  0.45
1992 Major EO, Amemiya K, Tornatore CS, Houff SA, Berger JR. Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clinical Microbiology Reviews. 5: 49-73. PMID 1310438 DOI: 10.1128/Cmr.5.1.49  0.471
1991 Tornatore C, Nath A, Amemiya K, Major EO. Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta. Journal of Virology. 65: 6094-100. PMID 1920627 DOI: 10.1128/Jvi.65.11.6094-6100.1991  0.507
1991 Assouline JG, Major EO. Human fetal Schwann cells support JC virus multiplication. Journal of Virology. 65: 1002-6. PMID 1846179  0.339
1991 Vitković L, Wood GP, Major EO, Fauci AS. Human astrocytes stimulate HIV-1 expression in a chronically infected promonocyte clone via interleukin-6. Aids Research and Human Retroviruses. 7: 723-7. PMID 1742078 DOI: 10.1089/Aid.1991.7.723  0.428
1990 Assouline JG, Levin MJ, Major EO, Forghani B, Straus SE, Ostrove JM. Varicella-zoster virus infection of human astrocytes, Schwann cells, and neurons. Virology. 179: 834-44. PMID 2173263 DOI: 10.1016/0042-6822(90)90152-H  0.403
1990 Major EO, Amemiya K, Elder G, Houff SA. Glial cells of the human developing brain and B cells of the immune system share a common DNA binding factor for recognition of the regulatory sequences of the human polyomavirus, JCV. Journal of Neuroscience Research. 27: 461-71. PMID 1964178 DOI: 10.1002/jnr.490270405  0.413
1989 Houff SA, Katz D, Kufta CV, Major EO. A rapid method for in situ hybridization for viral DNA in brain biopsies from patients with AIDS. Aids (London, England). 3: 843-5. PMID 2561055 DOI: 10.1097/00002030-198912000-00010  0.351
1989 Major EO, Vacante DA. Human fetal astrocytes in culture support the growth of the neurotropic human polyomavirus, JCV. Journal of Neuropathology and Experimental Neurology. 48: 425-36. PMID 2543798 DOI: 10.1097/00005072-198907000-00004  0.406
1989 Vacante DA, Traub R, Major EO. Extension of JC virus host range to monkey cells by insertion of a simian virus 40 enhancer into the JC virus regulatory region. Virology. 170: 353-61. PMID 2543122 DOI: 10.1016/0042-6822(89)90425-X  0.377
1988 Elder GA, Major EO. Early appearance of type II astrocytes in developing human fetal brain. Brain Research. 470: 146-50. PMID 3409045 DOI: 10.1016/0165-3806(88)90211-8  0.33
1988 Houff SA, Major EO, Katz DA, Kufta CV, Sever JL, Pittaluga S, Roberts JR, Gitt J, Saini N, Lux W. Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. The New England Journal of Medicine. 318: 301-5. PMID 2827029 DOI: 10.1056/Nejm198802043180507  0.42
1987 Major EO, Vacante DA, Traub RG, London WT, Sever JL. Owl monkey astrocytoma cells in culture spontaneously produce infectious JC virus which demonstrates altered biological properties. Journal of Virology. 61: 1435-41. PMID 3033272 DOI: 10.1128/Jvi.61.5.1435-1441.1987  0.372
1986 Major EO, Traub RG. JC virus T protein during productive infection in human fetal brain and kidney cells. Virology. 148: 221-5. PMID 3002030 DOI: 10.1016/0042-6822(86)90418-6  0.378
1985 Aksamit AJ, Mourrain P, Sever JL, Major EO. Progressive multifocal leukoencephalopathy: investigation of three cases using in situ hybridization with JC virus biotinylated DNA probe. Annals of Neurology. 18: 490-6. PMID 3000279 DOI: 10.1002/Ana.410180412  0.379
1985 Major EO, Miller AE, Mourrain P, Traub RG, de Widt E, Sever J. Establishment of a line of human fetal glial cells that supports JC virus multiplication. Proceedings of the National Academy of Sciences of the United States of America. 82: 1257-61. PMID 2983332 DOI: 10.1073/Pnas.82.4.1257  0.437
1984 Major EO, Matsumura P. Human embryonic kidney cells: stable transformation with an origin-defective simian virus 40 DNA and use as hosts for human papovavirus replication. Molecular and Cellular Biology. 4: 379-82. PMID 6321962 DOI: 10.1128/Mcb.4.2.379  0.356
1984 Major EO, Mourrain P, Cummins C. JC virus-induced owl monkey glioblastoma cells in culture: biological properties associated with the viral early gene product. Virology. 136: 359-67. PMID 6087549 DOI: 10.1016/0042-6822(84)90172-7  0.38
1980 Olive DM, Lampert M, Major EO. Comparison of wild-type BK virus DNA and BK virion DNA rescued from virus-transformed BHK cells. Virology. 103: 1-10. PMID 6245520 DOI: 10.1016/0042-6822(80)90121-X  0.381
1978 Bourne KA, Major EO, Khoobyarian N. A variant of adenovirus 12 producing cytoplasmic accumulation of capsid proteins. The Journal of General Virology. 40: 685-9. PMID 690616 DOI: 10.1099/0022-1317-40-3-685  0.323
1976 Wright PJ, Bernhardt G, Major EO, di Mayorca G. Comparison of the serology, transforming ability, and polypeptide composition of human papovaviruses isolated from urine. Journal of Virology. 17: 762-75. PMID 56460 DOI: 10.1128/Jvi.17.3.762-775.1976  0.352
1973 Major EO, Di Mayorca G. Malignant transformation of BHK21 clone 13 cells by BK virus--a human papovavirus. Proceedings of the National Academy of Sciences of the United States of America. 70: 3210-2. PMID 4361683 DOI: 10.1073/Pnas.70.11.3210  0.368
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