Arun P. Wiita, Ph.D. - Publications

Affiliations: 
Columbia University, New York, NY 

16/99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Huang HH, Ferguson ID, Thornton AM, Bastola P, Lam C, Lin YT, Choudhry P, Mariano MC, Marcoulis MD, Teo CF, Malato J, Phojanakong PJ, Martin TG, Wolf JL, Wong SW, ... ... Wiita AP, et al. Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma. Nature Communications. 11: 1931. PMID 32321912 DOI: 10.1038/S41467-020-15521-4  0.308
2018 Choudhry P, Galligan D, Wiita AP. Seeking Convergence and Cure with New Myeloma Therapies. Trends in Cancer. 4: 567-582. PMID 30064664 DOI: 10.1016/J.Trecan.2018.05.005  0.302
2018 Ferguson I, Lam C, Mariano MC, Wang D, Phojanakong P, Toumivaara S, Shao H, Hann BC, Gestwicki J, Wiita AP. Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma Blood. 132: 3212-3212. DOI: 10.1182/Blood-2018-99-117401  0.332
2017 Le Moigne R, Aftab BT, Djakovic S, Dhimolea E, Valle E, Murnane M, King EM, Soriano F, Menon MK, Wu ZY, Wong ST, Lee GJ, Yao B, Wiita AP, Lam C, et al. The p97 inhibitor CB-5083 is a unique disrupter of protein homeostasis in models of Multiple Myeloma. Molecular Cancer Therapeutics. PMID 28878026 DOI: 10.1158/1535-7163.Mct-17-0233  0.309
2017 Liu TY, Huang HH, Wheeler D, Xu Y, Wells JA, Song YS, Wiita AP. Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics. Cell Systems. PMID 28578850 DOI: 10.1016/J.Cels.2017.05.001  0.311
2016 Julien O, Zhuang M, Wiita AP, O'Donoghue AJ, Knudsen GM, Craik CS, Wells JA. Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles. Proceedings of the National Academy of Sciences of the United States of America. PMID 27006500 DOI: 10.1073/Pnas.1524900113  0.346
2014 Wiita AP, Seaman JE, Wells JA. Global analysis of cellular proteolysis by selective enzymatic labeling of protein N-termini. Methods in Enzymology. 544: 327-58. PMID 24974296 DOI: 10.1016/B978-0-12-417158-9.00013-3  0.357
2009 Perez-Jimenez R, Li J, Kosuri P, Sanchez-Romero I, Wiita AP, Rodriguez-Larrea D, Chueca A, Holmgren A, Miranda-Vizuete A, Becker K, Cho SH, Beckwith J, Gelhaye E, Jacquot JP, Gaucher EA, et al. Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nature Structural & Molecular Biology. 16: 890-6. PMID 19597482 DOI: 10.1038/Nsmb.1627  0.786
2008 Perez-Jimenez R, Wiita AP, Rodriguez-Larrea D, Kosuri P, Gavira JA, Sanchez-Ruiz JM, Fernandez JM. Force-clamp spectroscopy detects residue co-evolution in enzyme catalysis. The Journal of Biological Chemistry. 283: 27121-9. PMID 18687682 DOI: 10.1074/Jbc.M803746200  0.742
2008 Koti Ainavarapu SR, Wiita AP, Dougan L, Uggerud E, Fernandez JM. Single-molecule force spectroscopy measurements of bond elongation during a bimolecular reaction. Journal of the American Chemical Society. 130: 6479-87. PMID 18433129 DOI: 10.1021/Ja800180U  0.775
2008 Ainavarapu SR, Wiita AP, Huang HH, Fernandez JM. A single-molecule assay to directly identify solvent-accessible disulfide bonds and probe their effect on protein folding. Journal of the American Chemical Society. 130: 436-7. PMID 18088123 DOI: 10.1021/Ja077851S  0.783
2008 Szoszkiewicz R, Ainavarapu SR, Wiita AP, Perez-Jimenez R, Sanchez-Ruiz JM, Fernandez JM. Dwell time analysis of a single-molecule mechanochemical reaction. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 1356-64. PMID 17999545 DOI: 10.1021/La702368B  0.752
2007 Wiita AP, Perez-Jimenez R, Walther KA, Gräter F, Berne BJ, Holmgren A, Sanchez-Ruiz JM, Fernandez JM. Probing the chemistry of thioredoxin catalysis with force. Nature. 450: 124-7. PMID 17972886 DOI: 10.1038/Nature06231  0.746
2007 Ainavarapu SR, Brujic J, Huang HH, Wiita AP, Lu H, Li L, Walther KA, Carrion-Vazquez M, Li H, Fernandez JM. Contour length and refolding rate of a small protein controlled by engineered disulfide bonds. Biophysical Journal. 92: 225-33. PMID 17028145 DOI: 10.1529/Biophysj.106.091561  0.699
2006 Wiita AP, Ainavarapu SR, Huang HH, Fernandez JM. Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques. Proceedings of the National Academy of Sciences of the United States of America. 103: 7222-7. PMID 16645035 DOI: 10.1073/Pnas.0511035103  0.793
2002 Kipp RA, Case MA, Wist AD, Cresson CM, Carrell M, Griner E, Wiita A, Albiniak PA, Chai J, Shi Y, Semmelhack MF, McLendon GL. Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners Biochemistry. 41: 7344-7349. PMID 12044166 DOI: 10.1021/Bi0121454  0.329
Low-probability matches (unlikely to be authored by this person)
2017 Embry M, Li X, Yu A, Abrahams C, Greenland NY, Wen KW, Jones C, DeAlmeida V, Krimm S, Krueger S, Matheny S, Kline T, Yam A, Stafford R, Wiita AP, et al. CD74 Is Expressed in Relapsed and Refractory Multiple Myeloma and Can be Targeted with a Novel Anti-CD74 Antibody Drug Conjugate, SΤRO-001 Blood. 130: 4420-4420. DOI: 10.1182/Blood.V130.Suppl_1.4420.4420  0.291
2018 Lin YT, Way GP, Mariano MC, Marcoulis M, Ferguson I, Greene CS, Wiita AP. Integrating Phosphoproteomics and Transcriptional Classifiers Reveals "Hidden Signaling" in Multiple Myeloma Including Differential KRAS and NRAS Mutant Effects Blood. 132: 469-469. DOI: 10.1182/Blood-2018-99-113683  0.284
2016 Lam C, Murnane M, Smith GA, Taunton J, Aftab BT, Wiita AP. Tofacitinib Reverses Growth Promoting Effects of the Bone Marrow Stromal Environment Though Inhibition of JAK1/STAT3 Signaling in Multiple Myeloma Blood. 128: 2098-2098. DOI: 10.1182/Blood.V128.22.2098.2098  0.281
2020 Kambhampati S, Wiita AP. Lessons Learned from Proteasome Inhibitors, the Paradigm for Targeting Protein Homeostasis in Cancer. Advances in Experimental Medicine and Biology. 1243: 147-162. PMID 32297217 DOI: 10.1007/978-3-030-40204-4_10  0.279
2018 Choudhry P, Mariano MC, Wiita AP. DNA Methyltransferase Inhibitors Increase Expression of CD38 and Enhance Daratumumab Efficacy in Multiple Myeloma Blood. 132: 5618-5618. DOI: 10.1182/Blood-2018-99-114206  0.279
2018 Abrahams CL, Li X, Embry M, Yu A, Krimm S, Krueger S, Greenland NY, Wen KW, Jones C, DeAlmeida V, Solis WA, Matheny S, Kline T, Yam AY, Stafford R, ... Wiita AP, et al. Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001. Oncotarget. 9: 37700-37714. PMID 30701025 DOI: 10.18632/Oncotarget.26491  0.278
2018 Ramkumar P, Leong J, Seyler M, Georgoulis SJ, Hyrenius Wittsten A, Choudhry P, Roybal K, Wiita AP, Kampmann M. Identifying Factors in Multiple Myeloma Controlling Response to B-Cell Maturation Antigen (BCMA)-Targeted Immunotherapy Using CRISPR-Based Functional Genomics Blood. 132: 1926-1926. DOI: 10.1182/Blood-2018-99-115368  0.275
2017 Buelow B, Pham D, Choudhry P, Dang K, Pratap P, Clarke S, Harris K, Jorgensen B, Aldred SF, Schellenberger U, Shah N, Trinklein N, Wiita AP, Iyer S, Schooten WV. T Cell Engagement without Cytokine Storm: A Novel Bcma x CD3 Antibody Killing Myeloma Cells with Minimal Cytokine Secretion Blood. 130: 501-501. DOI: 10.1182/Blood.V130.Suppl_1.501.501  0.273
2020 Chan LN, Murakami MA, Robinson ME, Caeser R, Sadras T, Lee J, Cosgun KN, Kume K, Khairnar V, Xiao G, Ahmed MA, Aghania E, Deb G, Hurtz C, Shojaee S, ... ... Wiita AP, et al. Signalling input from divergent pathways subverts B cell transformation. Nature. PMID 32699415 DOI: 10.1038/S41586-020-2513-4  0.272
2019 Chan LN, Murakami MA, Caesar R, Hurtz C, Kume K, Sadras T, Shojaee S, Pölönen P, Ugale A, Lee J, Cosgun KN, Geng H, Heinäniemi M, Lohi O, Wiita AP, et al. Signaling Input from Divergent Pathways Subverts Malignant B-Cell Transformation Blood. 134: 3944-3944. DOI: 10.1182/Blood-2019-130774  0.272
2015 Murnane M, Dhimolea E, Li R, Bariteau MA, Wheeler DD, Akhurst RJ, Logan AC, Munster P, Wiita A, Martin TG, Wolf JL, Liu JO, Mitsiades CS, Aftab BT. Defining Primary Marrow Microenvironment-Induced Synthetic Lethality and Resistance for 2,684 Approved Drugs Across Molecularly Distinct Forms of Multiple Myeloma Blood. 126: 503-503. DOI: 10.1182/Blood.V126.23.503.503  0.271
2019 Spector JD, Wiita AP. ClinTAD: a tool for copy number variant interpretation in the context of topologically associated domains. Journal of Human Genetics. PMID 30765865 DOI: 10.1038/S10038-019-0573-9  0.269
2014 Wiita AP, Hsu GW, Lu CM, Esensten JH, Wells JA. Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling. Proceedings of the National Academy of Sciences of the United States of America. 111: 7594-9. PMID 24821784 DOI: 10.1073/Pnas.1405987111  0.269
2013 Wiita AP, Ziv E, Wiita PJ, Urisman A, Julien O, Burlingame AL, Weissman JS, Wells JA. Global cellular response to chemotherapy-induced apoptosis. Elife. 2: e01236. PMID 24171104 DOI: 10.7554/Elife.01236  0.267
2020 Leidal AM, Huang HH, Marsh T, Solvik T, Zhang D, Ye J, Kai F, Goldsmith J, Liu JY, Huang YH, Monkkonen T, Vlahakis A, Huang EJ, Goodarzi H, Yu L, ... Wiita AP, et al. The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. Nature Cell Biology. PMID 31932738 DOI: 10.1038/S41556-019-0450-Y  0.263
2014 Carr SA, Abbatiello SE, Ackermann BL, Borchers C, Domon B, Deutsch EW, Grant RP, Hoofnagle AN, Hüttenhain R, Koomen JM, Liebler DC, Liu T, MacLean B, Mani DR, Mansfield E, ... ... Wiita A, et al. Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach. Molecular & Cellular Proteomics : McP. 13: 907-17. PMID 24443746 DOI: 10.1074/Mcp.M113.036095  0.262
2019 Lin YT, Way GP, Barwick BG, Mariano MC, Marcoulis M, Ferguson ID, Driessen C, Boise LH, Greene CS, Wiita AP. Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma. Blood Advances. 3: 3214-3227. PMID 31698452 DOI: 10.1182/Bloodadvances.2019000303  0.261
2019 Nix M, Lin YT, Geng H, Marcoulis M, Phojanakong P, Wang D, Steri V, Whitman J, Bapat S, Stieglitz E, Deucher A, White KL, Hann BC, Wiita AP. In Vitro-Selected Nanobody-Based Cellular Therapy Targeting CD72 for Treatment of Refractory B-Cell Malignancies Blood. 134: 1337-1337. DOI: 10.1182/Blood-2019-130938  0.259
2019 Lorentsen K, Sankaran P, Trinklein ND, Pham D, Schellenberger U, Buelow B, Boudreau A, Choudhry P, Clarke SC, Dang K, Harris KE, Iyer S, Jorgensen B, Pratap P, Rangaswamy US, ... ... Wiita AP, et al. Abstract 1554: Uncoupling tumor-cell cytotoxicity from cytokine release with novel T-cell engaging bispecific antibodies Cancer Research. 79: 1554-1554. DOI: 10.1158/1538-7445.Am2019-1554  0.259
2018 Buelow B, Choudhry P, Clarke S, Dang K, Davison L, Force Aldred S, Harris K, Pham D, Pratap P, Rangaswamy U, Schellenberger U, Shah N, Trinklein N, Ugamraj H, Wiita A, et al. Development of a fully human t-cell engaging bispecific antibody for the treatment of multiple myeloma. Journal of Clinical Oncology. 36: 60-60. DOI: 10.1200/Jco.2018.36.5_Suppl.60  0.258
2016 Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita AP, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B. CD46 Is Amplified in High-Risk Myeloma with Gain of Chromosome 1q and Selectively Targeted By a Novel Anti-CD46 Antibody-Drug Conjugate Blood. 128: 384-384. DOI: 10.1182/Blood.V128.22.384.384  0.257
2019 Choudhry P, Mariano MC, Geng H, Martin TG, Wolf JL, Wong SW, Shah N, Wiita AP. DNA methyltransferase inhibitors upregulate CD38 protein expression and enhance daratumumab efficacy in multiple myeloma. Leukemia. PMID 31595037 DOI: 10.1038/S41375-019-0587-5  0.254
2018 Lee J, Geng H, Dinson DS, Xiao G, Cosgun KN, Chan LN, Chen Z, Farzan M, Jung JU, Wiita AP, Muschen M. IFITM3-Mediated Regulation of Cell Membrane Dynamics Is Essential for Malignant B-Cell Transformation Blood. 132: 552-552. DOI: 10.1182/Blood-2018-99-117472  0.254
2020 Ramkumar P, Abarientos AB, Tian R, Seyler M, Leong JT, Chen M, Choudhry P, Hechler T, Shah N, Wong SW, Martin TG, Wolf JL, Roybal KT, Pahl A, Taunton J, ... Wiita AP, et al. CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma. Blood Advances. 4: 2899-2911. PMID 32589729 DOI: 10.1182/Bloodadvances.2019001346  0.252
2013 Miller S, Wiita A, Wright C, Reyes H, Liu C. Evaluation of Glutamate Dehydrogenase Immunoassay Screening with Toxin Confirmation for the Diagnosis of Clostridium difficile Infection Labmedicine. 44. DOI: 10.1309/Lm31Zx1Pfrztgjui  0.252
2018 Lam C, Ferguson ID, Mariano MC, Lin YT, Murnane M, Liu H, Smith GA, Wong SW, Taunton J, Liu JO, Mitsiades CS, Hann BC, Aftab BT, Wiita AP. Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment. Haematologica. PMID 29622655 DOI: 10.3324/Haematol.2017.174482  0.251
2019 Trinklein ND, Pham D, Schellenberger U, Buelow B, Boudreau A, Choudhry P, Clarke SC, Dang K, Harris KE, Iyer S, Jorgensen B, Pratap PP, Rangaswamy US, Ugamraj HS, Vafa O, ... Wiita AP, et al. Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies. Mabs. PMID 30698484 DOI: 10.1080/19420862.2019.1574521  0.25
2019 Lee J, Xiao G, Cosgun KNN, Geng H, Ma N, Chan LN, Kume K, Nix M, Chen Z, Chen CD, Chen J, Khairnar V, Wiita AP, Thomas-Tikhonenko A, Farzan M, et al. Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis Blood. 134: 2782-2782. DOI: 10.1182/Blood-2019-127615  0.25
2020 Kambhampati S, Wen KW, Sung V, Wong SWK, Martin TG, Wolf JL, Shah N, Wiita A. Investigating macrophage function as a mechanism of resistance to daratumumab in relapsed refractory multiple myeloma patients. Journal of Clinical Oncology. 38: e20547-e20547. DOI: 10.1200/Jco.2020.38.15_Suppl.E20547  0.248
2020 Sarin V, Yu K, Ferguson ID, Gugliemini O, Nix MA, Hann B, Sirota M, Wiita AP. Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis. Leukemia. PMID 32123307 DOI: 10.1016/J.Clml.2019.09.120  0.245
2016 Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B. Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells. The Journal of Clinical Investigation. PMID 27841764 DOI: 10.1172/Jci85856  0.244
2016 Mather C, Qi Z, Wiita AP. False Positive Cell Free DNA Screening for Microdeletions Due to Non-Pathogenic Copy Number Variants. Prenatal Diagnosis. PMID 27061292 DOI: 10.1002/Pd.4823  0.242
2011 Wiita AP, Schrijver I. Clinical application of high throughput molecular screening techniques for pharmacogenomics. Pharmacogenomics and Personalized Medicine. 4: 109-21. PMID 23226057 DOI: 10.2147/Pgpm.S15302  0.241
2019 Ferguson I, Lin YT, Tuomivaara S, Wolf JL, Martin TG, Wong SW, Shah ND, Driessen C, Ness BGV, Wiita AP. Profiling the Cell Surface Landscape of Proteasome Inhibitor-Treated and –Resistant Multiple Myeloma to Guide Immunotherapy Targeting, Diagnosis, and Biology Blood. 134: 1803-1803. DOI: 10.1182/Blood-2019-131681  0.24
2020 Han LM, Grenert JP, Wiita AP, Quinn M, Fujimoto VY, Rabban JT. Prevalence of Partial Hydatidiform Mole in Products of Conception From Gestations With Fetal Triploidy Merits Reflex Genotype Testing Independent of the Morphologic Appearance of the Chorionic Villi. The American Journal of Surgical Pathology. PMID 32205485 DOI: 10.1097/Pas.0000000000001466  0.236
2012 Wiita AP, Nambiar A. Longitudinal management with crossmatch-compatible platelets for refractory patients: alloimmunization, response to transfusion, and clinical outcomes (CME). Transfusion. 52: 2146-54. PMID 23113654 DOI: 10.1111/J.1537-2995.2012.03593.X  0.235
2020 Guo X, Aviles G, Liu Y, Tian R, Unger BA, Lin YT, Wiita AP, Xu K, Correia MA, Kampmann M. Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway. Nature. PMID 32132707 DOI: 10.1038/S41586-020-2078-2  0.231
2018 Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, ... ... Wiita AP, et al. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nature Communications. 9: 810. PMID 29476136 DOI: 10.1038/S41467-018-02826-8  0.224
2019 Crottès D, Lin YT, Peters CJ, Gilchrist JM, Wiita AP, Jan YN, Jan LY. TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31182586 DOI: 10.1073/Pnas.1900703116  0.224
2012 Wiita AP, Roubinian N, Khan Y, Chin-Hong PV, Singer JP, Golden JA, Miller S. Cytomegalovirus disease and infection in lung transplant recipients in the setting of planned indefinite valganciclovir prophylaxis. Transplant Infectious Disease : An Official Journal of the Transplantation Society. 14: 248-58. PMID 22385394 DOI: 10.1111/J.1399-3062.2012.00723.X  0.222
2019 Choudhry P, Mariano M, Geng H, Wiita A. DNA methyltransferase inhibitors upregulate CD38 expression and enhance daratumumab efficacy in multiple myeloma Clinical Lymphoma, Myeloma & Leukemia. 19. DOI: 10.1016/J.Clml.2019.09.241  0.219
2019 Ha TK, Mardy AH, Beleford D, Spanier A, Wayman BV, Penon-Portmann M, Wiita AP, Shieh JT. X-linked duplication copy number variation in a familial overgrowth condition. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 31762227 DOI: 10.1002/Ajmg.C.31756  0.218
2016 Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, Jan YN. Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. PMID 27112495 DOI: 10.1016/J.Neuron.2016.03.027  0.217
2018 Buelow B, Choudry P, Clarke S, Dang K, Davison L, Force Aldred S, Harris K, Pratap P, Pham D, Rangaswamy U, Schellenberger U, Shah N, Trinklein N, Ugamraj H, Wiita A, et al. Pre-clinical development of TNB-383B, a fully human T-cell engaging bispecific antibody targeting BCMA for the treatment of multiple myeloma. Journal of Clinical Oncology. 36: 8034-8034. DOI: 10.1200/Jco.2018.36.15_Suppl.8034  0.215
2020 Mardy AH, Wiita AP, Wayman BV, Drexler K, Sparks TN, Norton ME. Variants of uncertain significance in prenatal microarrays: a retrospective cohort study. Bjog : An International Journal of Obstetrics and Gynaecology. PMID 32702189 DOI: 10.1111/1471-0528.16427  0.214
2017 Qi Z, Madaan S, Chetty S, Yu J, Wiita AP. False Negative Fetal Cell Free DNA Screening for Microdeletion Syndromes in the Presence of an Unbalanced Translocation Involving Monosomy 4p. Prenatal Diagnosis. PMID 28207935 DOI: 10.1002/Pd.5027  0.213
2017 Deshpande A, Yadav S, Dao DQ, Wu ZY, Hokanson KC, Cahill MK, Wiita AP, Jan YN, Ullian EM, Weiss LA. Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. Cell Reports. 21: 2678-2687. PMID 29212016 DOI: 10.1016/J.Celrep.2017.11.037  0.212
2017 Wiita A, Liu H, Lam C, Jandeleit B, Fischer W, Koller K, Hann B. Hijacking Myeloma Metabolism to Target Cytotoxic Chemotherapy to Malignant Plasma Cells With Decreased Bone Marrow Toxicity Clinical Lymphoma, Myeloma & Leukemia. 17. DOI: 10.1016/J.Clml.2017.03.096  0.21
2018 Whitman J, Ng D, Nix M, Leung K, Balassanian R, Wiita A. Fine Needle Aspiration is an Effective Method for Cell Surface Proteomics: Towards a Personalized Cancer Surfaceome Journal of the American Society of Cytopathology. 7. DOI: 10.1016/J.Jasc.2018.06.013  0.206
2013 Wiita AP, Ziv E, Wiita PJ, Urisman A, Julien O, Burlingame AL, Weissman JS, Wells JA. Correction: Global cellular response to chemotherapy-induced apoptosis Elife. 2. DOI: 10.7554/Elife.01816  0.198
2019 Mardy AH, Sparks TN, Wiita AP, Drexler K, Wayman BV, Nadel A, Norton ME. 880: Variants of uncertain significance in prenatal microarrays American Journal of Obstetrics and Gynecology. 220. DOI: 10.1016/J.Ajog.2018.11.904  0.196
2023 Tuomivaara ST, Teo CF, Jan YN, Jan LY, Wiita AP. SLAPSHOT reveals rapid dynamics of extracellularly exposed proteome in response to calcium-activated plasma membrane phospholipid scrambling. Biorxiv : the Preprint Server For Biology. PMID 36993417 DOI: 10.1101/2023.03.26.534250  0.195
2013 Wiita AP, Ziv E, Wiita PJ, Urisman A, Julien O, Burlingame AL, Weissman JS, Wells JA. Author response: Global cellular response to chemotherapy-induced apoptosis Elife. DOI: 10.7554/Elife.01236.036  0.183
2023 Mandal K, Wicaksono G, Yu C, Adams JJ, Hoopmann MR, Temple WC, Izgutdina A, Escobar BP, Gorelik M, Ihling CH, Nix MA, Naik A, Xie WH, Hübner J, Rollins LA, ... ... Wiita AP, et al. Structural surfaceomics reveals an AML-specific conformation of integrin β as a CAR T cellular therapy target. Nature Cancer. PMID 37904046 DOI: 10.1038/s43018-023-00652-6  0.157
2022 Patiño-Escobar B, Ferguson ID, Wiita AP. Unraveling the surface proteomic profile of multiple myeloma to reveal new immunotherapeutic targets and markers of drug resistance. Cell Stress. 6: 89-92. PMID 36311892 DOI: 10.15698/cst2022.11.273  0.136
2022 Ferguson ID, Patiño-Escobar B, Tuomivaara ST, Lin YT, Nix MA, Leung KK, Kasap C, Ramos E, Nieves Vasquez W, Talbot A, Hale M, Naik A, Kishishita A, Choudhry P, Lopez-Girona A, ... ... Wiita AP, et al. The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance. Nature Communications. 13: 4121. PMID 35840578 DOI: 10.1038/s41467-022-31810-6  0.133
2023 Naik A, Srivastava S, Wiita AP. "Cell Surface Capture" Workflow for Label-Free Quantification of the Cell Surface Proteome. Journal of Visualized Experiments : Jove. PMID 37036222 DOI: 10.3791/64952  0.129
2023 Patiño-Escobar B, Talbot A, Wiita AP. Overcoming proteasome inhibitor resistance in the immunotherapy era. Trends in Pharmacological Sciences. 44: 507-518. PMID 37344251 DOI: 10.1016/j.tips.2023.05.006  0.127
2020 Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Lim SA, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, et al. Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 32766586 DOI: 10.1101/2020.07.31.231746  0.126
2020 Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, et al. Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America. PMID 33093202 DOI: 10.1073/pnas.2016093117  0.121
2022 Sharma A, Nair R, Achreja A, Mittal A, Gupta P, Balakrishnan K, Edgar CL, Animasahun O, Dwivedi B, Barwick BG, Gupta VA, Matulis SM, Bhasin M, Lonial S, Nooka AK, ... Wiita AP, et al. Therapeutic implications of mitochondrial stress-induced proteasome inhibitor resistance in multiple myeloma. Science Advances. 8: eabq5575. PMID 36170375 DOI: 10.1126/sciadv.abq5575  0.116
2020 Lee J, Robinson ME, Ma N, Artadji D, Ahmed MA, Xiao G, Sadras T, Deb G, Winchester J, Cosgun KN, Geng H, Chan LN, Kume K, Miettinen TP, Zhang Y, ... ... Wiita AP, et al. IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells. Nature. PMID 33149299 DOI: 10.1038/s41586-020-2884-6  0.11
2022 Ferguson ID, Lin YT, Lam C, Shao H, Tharp KM, Hale M, Kasap C, Mariano MC, Kishishita A, Patiño Escobar B, Mandal K, Steri V, Wang D, Phojanakong P, Tuomivaara ST, ... ... Wiita AP, et al. Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma. Cell Chemical Biology. PMID 35853457 DOI: 10.1016/j.chembiol.2022.06.010  0.107
2023 Ge AY, Huang CY, Banerjee R, Knoche J, Chung A, Arora S, Martin TG, Wolf J, Wong SW, Wiita AP, Shah N. Cytomegalovirus seropositivity is associated with improved responses to CD38 monoclonal antibody therapies in multiple myeloma: A single-centre retrospective study. British Journal of Haematology. PMID 36846905 DOI: 10.1111/bjh.18711  0.104
2023 Wadhwa A, Wang S, Patiño-Escobar B, Bidkar AP, Bobba KN, Chan E, Meher N, Bidlingmaier S, Su Y, Dhrona S, Geng H, Sarin V, VanBrocklin HF, Wilson DM, He J, ... ... Wiita AP, et al. CD46-targeted theranostics for Positron Emission Tomography and 225Ac-Radiopharmaceutical Therapy of Multiple Myeloma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 38109209 DOI: 10.1158/1078-0432.CCR-23-2130  0.104
2021 Liu JY, Lin YT, Leidal AM, Huang HH, Ye J, Wiita AP, Debnath J. GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network. Biology Open. PMID 34533192 DOI: 10.1242/bio.058736  0.101
2022 Kai F, Ou G, Tourdot RW, Stashko C, Gaietta G, Swift MF, Volkmann N, Long AF, Han Y, Huang HH, Northey JJ, Leidal AM, Viasnoff V, Bryant DM, Guo W, ... Wiita AP, et al. ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells. The Embo Journal. e109205. PMID 35880301 DOI: 10.15252/embj.2021109205  0.1
2024 Nejo T, Wang L, Leung KK, Wang A, Lakshmanachetty S, Gallus M, Kwok DW, Hong C, Chen LH, Carrera DA, Zhang MY, Stevers NO, Maldonado GC, Yamamichi A, Watchmaker PB, ... ... Wiita AP, et al. Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma. Scientific Reports. 14: 6362. PMID 38493204 DOI: 10.1038/s41598-024-56684-0  0.097
2024 Kasap C, Izgutdina A, Patiño-Escobar B, Kang A, Chilakapati N, Akagi N, Johnson H, Rashid T, Werner J, Barpanda A, Geng H, Lin YT, Rampersaud S, Gil-Alós D, Sobh A, ... ... Wiita AP, et al. Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells. Biorxiv : the Preprint Server For Biology. PMID 38463958 DOI: 10.1101/2024.02.24.581875  0.095
2020 Spector JD, Wiita AP. A Guide to Using ClinTAD for Interpretation of DNA Copy Number Variants in the Context of Topologically Associated Domains. Current Protocols in Human Genetics. 108: e106. PMID 33170544 DOI: 10.1002/cphg.106  0.094
2023 Kwok DW, Stevers NO, Nejo T, Chen LH, Etxeberria I, Jung J, Okada K, Cove MC, Lakshmanachetty S, Gallus M, Barpanda A, Hong C, Chan GKL, Wu SH, Ramos E, ... ... Wiita AP, et al. Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens. Biorxiv : the Preprint Server For Biology. PMID 37904942 DOI: 10.1101/2023.10.19.563178  0.091
2024 Nix MA, Wiita AP. Alternative target recognition elements for chimeric antigen receptor (CAR) T cells: beyond standard antibody fragments. Cytotherapy. PMID 38466264 DOI: 10.1016/j.jcyt.2024.02.024  0.088
2021 Nix MA, Mandal K, Geng H, Paranjape N, Lin YT, Rivera J, Marcoulis M, White KL, Whitman JD, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, ... ... Wiita AP, et al. Surface proteomics reveals CD72 as a target for in vitro-evolved nanobody-based CAR-T cells in KMT2A/MLL1-rearranged B-ALL. Cancer Discovery. PMID 33727310 DOI: 10.1158/2159-8290.CD-20-0242  0.087
2023 Temple WC, Nix MA, Naik A, Izgutdina A, Huang BJ, Wicaksono G, Phojanakong P, Serrano JAC, Young EP, Ramos E, Salangsang F, Steri V, Xirenayi S, Hermiston M, Logan AC, ... ... Wiita AP, et al. Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies. Journal For Immunotherapy of Cancer. 11. PMID 38007238 DOI: 10.1136/jitc-2023-006985  0.087
2021 Bigley AB, Spade S, Agha NH, Biswas S, Tang S, Malik MH, Dai L, Masoumi S, Patiño-Escobar B, Hale M, DiPierro G, Martell R, Hann B, Shah N, Wiita AP, et al. FcεRIγ-negative NK cells persist in vivo and enhance efficacy of therapeutic monoclonal antibodies in multiple myeloma. Blood Advances. 5: 3021-3031. PMID 34357379 DOI: 10.1182/bloodadvances.2020002440  0.086
2023 Paranjape N, Lin YT, Flores-Ramirez Q, Sarin V, Johnson AB, Chu J, Paredes M, Wiita AP. A CRISPR-engineered isogenic model of the 22q11.2 A-B syndromic deletion. Scientific Reports. 13: 7689. PMID 37169815 DOI: 10.1038/s41598-023-34325-2  0.074
2022 Solvik TA, Nguyen TA, Tony Lin YH, Marsh T, Huang EJ, Wiita AP, Debnath J, Leidal AM. Secretory autophagy maintains proteostasis upon lysosome inhibition. The Journal of Cell Biology. 221. PMID 35446347 DOI: 10.1083/jcb.202110151  0.072
2023 Gökbuget D, Lenshoek K, Boileau RM, Bayerl J, Huang H, Wiita AP, Laird DJ, Blelloch R. Transcriptional repression upon S phase entry protects genome integrity in pluripotent cells. Nature Structural & Molecular Biology. 30: 1561-1570. PMID 37696959 DOI: 10.1038/s41594-023-01092-7  0.069
2024 Shin D, Kim CN, Ross J, Hennick KM, Wu SR, Paranjape N, Leonard R, Wang JC, Keefe MG, Pavlovic BJ, Donohue KC, Moreau C, Wigdor EM, Larson HH, Allen DE, ... ... Wiita AP, et al. Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders. Cell Stem Cell. PMID 38382530 DOI: 10.1016/j.stem.2024.01.010  0.058
2023 Nejo T, Wang L, Leung KK, Wang A, Lakshmanachetty S, Gallus M, Kwok DW, Hong C, Chen LH, Carrera DA, Zhang MY, Stevers NO, Maldonado GC, Yamamichi A, Watchmaker P, ... ... Wiita AP, et al. Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma. Biorxiv : the Preprint Server For Biology. PMID 37961484 DOI: 10.1101/2023.10.26.564156  0.057
2024 Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V. Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy. Neurology. Genetics. 10: e200142. PMID 38586598 DOI: 10.1212/NXG.0000000000200142  0.053
2024 Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal N, Glenn O, Kamiya S, Wiita A, Berger A, Shieh JT, Titus EW, Paredes MF, Upadhyay V. Cell type specificity of mosaic chromosome 1q gain resolved by snRNA-seq in a case of epilepsy with hyaline protoplasmic astrocytopathy. Biorxiv : the Preprint Server For Biology. PMID 38328093 DOI: 10.1101/2023.10.16.562560  0.053
2021 Lee J, Robinson ME, Ma N, Artadji D, Ahmed MA, Xiao G, Sadras T, Deb G, Winchester J, Cosgun KN, Geng H, Chan LN, Kume K, Miettinen TP, Zhang Y, ... ... Wiita AP, et al. Author Correction: IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells. Nature. PMID 33712811 DOI: 10.1038/s41586-021-03388-4  0.048
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