Year |
Citation |
Score |
2016 |
Nickell JR, Siripurapu KB, Horton DB, Zheng G, Crooks PA, Dwoskin LP. GZ-793A inhibits the neurochemical effects of methamphetamine via a selective interaction with the vesicular monoamine transporter-2. European Journal of Pharmacology. 795: 143-149. PMID 27986625 DOI: 10.1016/J.Ejphar.2016.12.016 |
0.661 |
|
2015 |
Beckmann JS, Meyer AC, Pivavarchyk M, Horton DB, Zheng G, Smith AM, Wooters TE, McIntosh JM, Crooks PA, Bardo MT, Dwoskin LP. r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement. Neurochemical Research. PMID 26227997 DOI: 10.1007/S11064-015-1680-4 |
0.667 |
|
2014 |
Wager TT, Chandrasekaran RY, Bradley J, Rubitski D, Berke H, Mente S, Butler T, Doran A, Chang C, Fisher K, Knafels J, Liu S, Ohren J, Marconi M, DeMarco G, ... ... Horton D, et al. Casein kinase 1δ/ε inhibitor PF-5006739 attenuates opioid drug-seeking behavior. Acs Chemical Neuroscience. 5: 1253-65. PMID 25299732 DOI: 10.1021/Cn500201X |
0.327 |
|
2013 |
Horton DB, Nickell JR, Zheng G, Crooks PA, Dwoskin LP. GZ-793A, a lobelane analog, interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine. Journal of Neurochemistry. 127: 177-86. PMID 23875622 DOI: 10.1111/Jnc.12371 |
0.669 |
|
2013 |
Horton DB, Potter DM, Mead AN. A translational pharmacology approach to understanding the predictive value of abuse potential assessments. Behavioural Pharmacology. 24: 410-36. PMID 23873088 DOI: 10.1097/Fbp.0B013E3283644D2E |
0.302 |
|
2013 |
Narayanaswami V, Somkuwar SS, Horton DB, Cassis LA, Dwoskin LP. Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [³H]dopamine and [³H]norepinephrine release. Biochemical Pharmacology. 86: 656-65. PMID 23831951 DOI: 10.1016/J.Bcp.2013.06.025 |
0.661 |
|
2013 |
Zheng G, Horton DB, Penthala NR, Nickell JR, Culver JP, Deaciuc AG, Dwoskin LP, Crooks PA. Exploring the effect of N-substitution in nor-lobelane on the interaction with VMAT2: discovery of a potential clinical candidate for treatment of methamphetamine abuse. Medchemcomm. 4: 564-568. PMID 23527317 DOI: 10.1039/C3Md20374C |
0.621 |
|
2011 |
Horton DB, Siripurapu KB, Zheng G, Crooks PA, Dwoskin LP. Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release. The Journal of Pharmacology and Experimental Therapeutics. 339: 286-97. PMID 21778282 DOI: 10.1124/Jpet.111.184770 |
0.67 |
|
2011 |
Meyer AC, Horton DB, Neugebauer NM, Wooters TE, Nickell JR, Dwoskin LP, Bardo MT. Tetrabenazine inhibition of monoamine uptake and methamphetamine behavioral effects: locomotor activity, drug discrimination and self-administration. Neuropharmacology. 61: 849-56. PMID 21669212 DOI: 10.1016/J.Neuropharm.2011.05.033 |
0.613 |
|
2011 |
Horton DB, Siripurapu KB, Norrholm SD, Culver JP, Hojahmat M, Beckmann JS, Harrod SB, Deaciuc AG, Bardo MT, Crooks PA, Dwoskin LP. meso-Transdiene analogs inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release. The Journal of Pharmacology and Experimental Therapeutics. 336: 940-51. PMID 21177475 DOI: 10.1124/Jpet.110.175117 |
0.752 |
|
2011 |
Crooks PA, Zheng G, Vartak AP, Culver JP, Zheng F, Horton DB, Dwoskin LP. Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse. Current Topics in Medicinal Chemistry. 11: 1103-27. PMID 21050177 DOI: 10.2174/156802611795371332 |
0.638 |
|
2010 |
Beckmann JS, Siripurapu KB, Nickell JR, Horton DB, Denehy ED, Vartak A, Crooks PA, Dwoskin LP, Bardo MT. The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 335: 841-51. PMID 20805303 DOI: 10.1124/Jpet.110.172742 |
0.719 |
|
2010 |
Hojahmat M, Horton DB, Norrholm SD, Miller DK, Grinevich VP, Deaciuc AG, Dwoskin LP, Crooks PA. Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters. Bioorganic & Medicinal Chemistry. 18: 640-9. PMID 20036131 DOI: 10.1016/J.Bmc.2009.12.002 |
0.696 |
|
2007 |
Norrholm SD, Horton DB, Dwoskin LP. The promiscuity of the dopamine transporter: implications for the kinetic analysis of [3H]serotonin uptake in rat hippocampal and striatal synaptosomes. Neuropharmacology. 53: 982-9. PMID 18022203 DOI: 10.1016/J.Neuropharm.2007.10.001 |
0.694 |
|
2006 |
Zheng G, Horton DB, Deaciuc AG, Dwoskin LP, Crooks PA. Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters. Bioorganic & Medicinal Chemistry Letters. 16: 5018-21. PMID 16905316 DOI: 10.1016/J.Bmcl.2006.07.070 |
0.687 |
|
Show low-probability matches. |