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Darren A. Cusanovich, Ph.D. - Publications

Affiliations: 
2013 Human Genetics University of Chicago, Chicago, IL 
Area:
Olfaction
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Adelus ML, Ding J, Tran BT, Conklin AC, Golebiewski AK, Stolze LK, Whalen MB, Cusanovich DA, Romanoski CE. Single-cell 'omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations. Elife. 12. PMID 38578680 DOI: 10.7554/eLife.91729  0.336
2024 Zhang H, Mulqueen RM, Iannuzo N, Farrera DO, Polverino F, Galligan JJ, Ledford JG, Adey AC, Cusanovich DA. txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility. Genome Biology. 25: 78. PMID 38519979 DOI: 10.1186/s13059-023-03150-1  0.662
2023 Welfley H, Kylat R, Zaghloul N, Halonen M, Martinez FD, Ahmed M, Cusanovich DA. Single-Cell Profiling of Premature Neonate Airways Reveals a Continuum of Myeloid Differentiation. American Journal of Respiratory Cell and Molecular Biology. PMID 37643399 DOI: 10.1165/rcmb.2022-0293OC  0.347
2023 Kang H, Fitch JC, Varghese RP, Thorne CA, Cusanovich DA. SGRN: A Cas12a-driven Synthetic Gene Regulatory Network System. Biorxiv : the Preprint Server For Biology. PMID 37214915 DOI: 10.1101/2023.05.08.539911  0.351
2021 Durham TJ, Daza RM, Gevirtzman L, Cusanovich D, Bolonduro O, Noble WS, Shendure J, Waterston RH. Comprehensive characterization of tissue-specific chromatin accessibility in L2 nematodes. Genome Research. PMID 33888511 DOI: 10.1101/gr.271791.120  0.666
2020 Domcke S, Hill AJ, Daza RM, Cao J, O'Day DR, Pliner HA, Aldinger KA, Pokholok D, Zhang F, Milbank JH, Zager MA, Glass IA, Steemers FJ, Doherty D, Trapnell C, ... Cusanovich DA, et al. A human cell atlas of fetal chromatin accessibility. Science (New York, N.Y.). 370. PMID 33184180 DOI: 10.1126/science.aba7612  0.778
2020 Rai V, Quang DX, Erdos MR, Cusanovich DA, Daza RM, Narisu N, Zou LS, Didion JP, Guan Y, Shendure J, Parker SCJ, Collins FS. Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures. Molecular Metabolism. 32: 109-121. PMID 32029221 DOI: 10.1016/J.Molmet.2019.12.006  0.601
2018 Allan CM, Heizer PJ, Tu Y, Sandoval NP, Jung RS, Morales JE, Sajti E, Troutman TD, Saunders TL, Cusanovich DA, Beigneux AP, Romanoski CE, Fong LG, Young SG. An upstream enhancer regulates expression in a tissue-specific manner. Journal of Lipid Research. PMID 30598475 DOI: 10.1194/Jlr.M091322  0.353
2018 Cao J, Cusanovich DA, Ramani V, Aghamirzaie D, Pliner HA, Hill AJ, Daza RM, McFaline-Figueroa JL, Packer JS, Christiansen L, Steemers FJ, Adey AC, Trapnell C, Shendure J. Joint profiling of chromatin accessibility and gene expression in thousands of single cells. Science (New York, N.Y.). PMID 30166440 DOI: 10.1126/Science.Aau0730  0.763
2018 Pliner HA, Packer JS, McFaline-Figueroa JL, Cusanovich DA, Daza RM, Aghamirzaie D, Srivatsan S, Qiu X, Jackson D, Minkina A, Adey AC, Steemers FJ, Shendure J, Trapnell C. Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data. Molecular Cell. PMID 30078726 DOI: 10.1016/J.Molcel.2018.06.044  0.732
2018 Cusanovich DA, Hill AJ, Aghamirzaie D, Daza RM, Pliner HA, Berletch JB, Filippova GN, Huang X, Christiansen L, DeWitt WS, Lee C, Regalado SG, Read DF, Steemers FJ, Disteche CM, et al. A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility. Cell. PMID 30078704 DOI: 10.1016/J.Cell.2018.06.052  0.701
2018 Cusanovich DA, Reddington JP, Garfield DA, Daza RM, Aghamirzaie D, Marco-Ferreres R, Pliner HA, Christiansen L, Qiu X, Steemers FJ, Trapnell C, Shendure J, Furlong EEM. The cis-regulatory dynamics of embryonic development at single-cell resolution. Nature. PMID 29539636 DOI: 10.1038/Nature25981  0.634
2017 Cao J, Packer JS, Ramani V, Cusanovich DA, Huynh C, Daza R, Qiu X, Lee C, Furlan SN, Steemers FJ, Adey A, Waterston RH, Trapnell C, Shendure J. Comprehensive single-cell transcriptional profiling of a multicellular organism. Science (New York, N.Y.). 357: 661-667. PMID 28818938 DOI: 10.1126/Science.Aam8940  0.74
2017 Gasperini M, Findlay GM, McKenna A, Milbank JH, Lee C, Zhang MD, Cusanovich DA, Shendure J. CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions. American Journal of Human Genetics. PMID 28712454 DOI: 10.1016/J.Ajhg.2017.06.010  0.663
2016 Ramani V, Cusanovich DA, Hause RJ, Ma W, Qiu R, Deng X, Blau CA, Disteche CM, Noble WS, Shendure J, Duan Z. Mapping 3D genome architecture through in situ DNase Hi-C. Nature Protocols. 11: 2104-2121. PMID 27685100 DOI: 10.1038/Nprot.2016.126  0.656
2016 Cusanovich DA, Caliskan M, Billstrand C, Michelini K, Chavarria C, De Leon S, Mitrano A, Lewellyn N, Elias JA, Chupp GL, Lang RM, Shah SJ, DeCara JM, Gilad Y, Ober C. Integrated Analyses of Gene Expression and Genetic Association Studies in a Founder Population. Human Molecular Genetics. PMID 26931462 DOI: 10.1093/Hmg/Ddw061  0.606
2015 Davenport ER, Cusanovich DA, Michelini K, Barreiro LB, Ober C, Gilad Y. Genome-Wide Association Studies of the Human Gut Microbiota. Plos One. 10: e0140301. PMID 26528553 DOI: 10.1371/Journal.Pone.0140301  0.569
2015 Cusanovich DA, Daza R, Adey A, Pliner HA, Christiansen L, Gunderson KL, Steemers FJ, Trapnell C, Shendure J. Epigenetics. Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing. Science (New York, N.Y.). 348: 910-4. PMID 25953818 DOI: 10.1126/Science.Aab1601  0.754
2015 Cusanovich DA, Daza R, Adey A, Pliner HA, Christiansen L, Gunderson KL, Steemers FJ, Trapnell C, Shendure J. Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing Science. 348: 910-914. DOI: 10.1126/science.aab1601  0.73
2014 Cusanovich DA, Pavlovic B, Pritchard JK, Gilad Y. The functional consequences of variation in transcription factor binding. Plos Genetics. 10: e1004226. PMID 24603674 DOI: 10.1371/Journal.Pgen.1004226  0.758
2013 Khan Z, Ford MJ, Cusanovich DA, Mitrano A, Pritchard JK, Gilad Y. Primate transcript and protein expression levels evolve under compensatory selection pressures. Science (New York, N.Y.). 342: 1100-4. PMID 24136357 DOI: 10.1126/Science.1242379  0.607
2012 Iskow RC, Gokcumen O, Abyzov A, Malukiewicz J, Zhu Q, Sukumar AT, Pai AA, Mills RE, Habegger L, Cusanovich DA, Rubel MA, Perry GH, Gerstein M, Stone AC, Gilad Y, et al. Regulatory element copy number differences shape primate expression profiles. Proceedings of the National Academy of Sciences of the United States of America. 109: 12656-61. PMID 22797897 DOI: 10.1073/Pnas.1205199109  0.752
2012 Cusanovich DA, Billstrand C, Zhou X, Chavarria C, De Leon S, Michelini K, Pai AA, Ober C, Gilad Y. The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Human Molecular Genetics. 21: 2111-23. PMID 22286170 DOI: 10.1093/Hmg/Dds021  0.739
2011 Caliskan M, Cusanovich DA, Ober C, Gilad Y. The effects of EBV transformation on gene expression levels and methylation profiles. Human Molecular Genetics. 20: 1643-52. PMID 21289059 DOI: 10.1093/Hmg/Ddr041  0.684
2009 Ober C, Nord AS, Thompson EE, Pan L, Tan Z, Cusanovich D, Sun Y, Nicolae R, Edelstein C, Schneider DH, Billstrand C, Pfaffinger D, Phillips N, Anderson RL, Philips B, et al. Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. Journal of Lipid Research. 50: 798-806. PMID 19124843 DOI: 10.1194/Jlr.M800515-Jlr200  0.339
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