Jeffrey J. Lochhead, Ph.D. - Publications

Affiliations: 
2011 Neuroscience University of Arizona, Tucson, AZ 
Area:
Pain, opioids, pharmacology

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lochhead JJ, Ronaldson PT, Davis TP. The role of oxidative stress in blood-brain barrier disruption during ischemic stroke: Antioxidants in clinical trials. Biochemical Pharmacology. 116186. PMID 38561092 DOI: 10.1016/j.bcp.2024.116186  0.677
2023 Williams EI, Betterton RD, Stanton JA, Moreno-Rodriguez VM, Lochhead JJ, Davis TP, Ronaldson PT. Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke. Stroke. 54: 2875-2885. PMID 37750296 DOI: 10.1161/STROKEAHA.123.043649  0.677
2023 Lochhead JJ, Williams EI, Reddell ES, Dorn E, Ronaldson PT, Davis TP. High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke. Cells. 12. PMID 36831312 DOI: 10.3390/cells12040645  0.692
2022 Yang J, Betterton RD, Williams EI, Stanton JA, Reddell ES, Ogbonnaya CE, Dorn E, Davis TP, Lochhead JJ, Ronaldson PT. High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats. Pharmaceutics. 14. PMID 35631535 DOI: 10.3390/pharmaceutics14050949  0.686
2022 Kwak EA, Pan CC, Ramonett A, Kumar S, Cruz-Flores P, Ahmed T, Ortiz HR, Lochhead JJ, Ellis NA, Mouneimne G, Georgieva TG, Lee YS, Vanderah TW, Largent-Milnes T, Mohler PJ, et al. β-spectrin as a stalk cell-intrinsic regulator of VEGF signaling. Nature Communications. 13: 1326. PMID 35288568 DOI: 10.1038/s41467-022-28933-1  0.628
2020 Lochhead JJ, Yang J, Ronaldson PT, Davis TP. Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders. Frontiers in Physiology. 11: 914. PMID 32848858 DOI: 10.3389/Fphys.2020.00914  0.718
2019 Lochhead JJ, Davis TP. Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration. Pharmaceutics. 11. PMID 31726721 DOI: 10.3390/Pharmaceutics11110598  0.59
2019 Lochhead JJ, Kellohen KL, Ronaldson PT, Davis TP. Distribution of insulin in trigeminal nerve and brain after intranasal administration. Scientific Reports. 9: 2621. PMID 30796294 DOI: 10.1038/S41598-019-39191-5  0.647
2018 Kumar NN, Lochhead JJ, Pizzo ME, Nehra G, Boroumand S, Greene G, Tnhorne RG. Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30081144 DOI: 10.1016/J.Jconrel.2018.08.006  0.458
2017 Lochhead JJ, Ronaldson PT, Davis TP. Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System. The Aaps Journal. PMID 28353217 DOI: 10.1208/S12248-017-0076-6  0.722
2016 Kumar NN, Gautam M, Lochhead JJ, Wolak DJ, Ithapu V, Singh V, Thorne RG. Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery. Scientific Reports. 6: 31732. PMID 27558973 DOI: 10.1038/Srep31732  0.4
2015 Lochhead JJ, Wolak DJ, Pizzo ME, Thorne RG. Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 371-81. PMID 25492117 DOI: 10.1038/Jcbfm.2014.215  0.466
2012 Lochhead JJ, Thorne RG. Intranasal delivery of biologics to the central nervous system. Advanced Drug Delivery Reviews. 64: 614-28. PMID 22119441 DOI: 10.1016/J.Addr.2011.11.002  0.467
2012 Lochhead JJ, McCaffrey G, Sanchez-Covarrubias L, Finch JD, Demarco KM, Quigley CE, Davis TP, Ronaldson PT. Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain. American Journal of Physiology. Heart and Circulatory Physiology. 302: H582-93. PMID 22081706 DOI: 10.1152/Ajpheart.00889.2011  0.711
2011 Lochhead JJ, McCaffrey G, Quigley CE, Finch J, Demarco KM, Nametz N, Davis TP. Erratum: Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation (Journal of Cerebral Blood Flow and Metabolism (2010) 30 (1625-1636) DOI: 10.1038/jcbfm.2010.29) Journal of Cerebral Blood Flow and Metabolism. 31: 790-791. DOI: 10.1038/Jcbfm.2010.177  0.421
2010 Lochhead JJ, McCaffrey G, Quigley CE, Finch J, DeMarco KM, Nametz N, Davis TP. Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1625-36. PMID 20234382 DOI: 10.1038/Jcbfm.2010.29  0.601
2009 McCaffrey G, Willis CL, Staatz WD, Nametz N, Quigley CA, Hom S, Lochhead JJ, Davis TP. Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress. Journal of Neurochemistry. 110: 58-71. PMID 19457074 DOI: 10.1111/J.1471-4159.2009.06113.X  0.673
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