| Year |
Citation |
Score |
| 2024 |
Lochhead JJ, Ronaldson PT, Davis TP. The role of oxidative stress in blood-brain barrier disruption during ischemic stroke: Antioxidants in clinical trials. Biochemical Pharmacology. 116186. PMID 38561092 DOI: 10.1016/j.bcp.2024.116186 |
0.489 |
|
| 2024 |
Ronaldson PT, Davis TP. Blood-brain barrier transporters: a translational consideration for CNS delivery of neurotherapeutics. Expert Opinion On Drug Delivery. PMID 38217410 DOI: 10.1080/17425247.2024.2306138 |
0.66 |
|
| 2023 |
Ronaldson PT, Williams EI, Betterton RD, Stanton JA, Nilles KL, Davis TP. CNS Drug Delivery in Stroke: Improving Therapeutic Translation From the Bench to the Bedside. Stroke. 55: 190-202. PMID 38134249 DOI: 10.1161/STROKEAHA.123.043764 |
0.755 |
|
| 2023 |
Williams EI, Betterton RD, Stanton JA, Moreno-Rodriguez VM, Lochhead JJ, Davis TP, Ronaldson PT. Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke. Stroke. 54: 2875-2885. PMID 37750296 DOI: 10.1161/STROKEAHA.123.043649 |
0.804 |
|
| 2023 |
Lochhead JJ, Williams EI, Reddell ES, Dorn E, Ronaldson PT, Davis TP. High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke. Cells. 12. PMID 36831312 DOI: 10.3390/cells12040645 |
0.742 |
|
| 2023 |
Betterton RD, Williams EI, Nilles KL, Davis TP, Ronaldson PT. Methods to Study Drug Uptake at the Blood-Brain Barrier Following Experimental Ischemic Stroke: In Vitro and In Vivo Approaches. Methods in Molecular Biology (Clifton, N.J.). 2616: 403-418. PMID 36715949 DOI: 10.1007/978-1-0716-2926-0_28 |
0.764 |
|
| 2022 |
Stanton JA, Williams EI, Betterton RD, Davis TP, Ronaldson PT. Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats. Experimental Neurology. 357: 114181. PMID 35905840 DOI: 10.1016/j.expneurol.2022.114181 |
0.678 |
|
| 2022 |
Ronaldson PT, Davis TP. Transport Mechanisms at the Blood-Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs. Pharmaceutics. 14. PMID 35890396 DOI: 10.3390/pharmaceutics14071501 |
0.71 |
|
| 2022 |
Yang J, Betterton RD, Williams EI, Stanton JA, Reddell ES, Ogbonnaya CE, Dorn E, Davis TP, Lochhead JJ, Ronaldson PT. High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats. Pharmaceutics. 14. PMID 35631535 DOI: 10.3390/pharmaceutics14050949 |
0.716 |
|
| 2022 |
Betterton RD, Abdullahi W, Williams EI, Lochhead JL, Brzica H, Stanton JA, Reddell E, Ogbonnaya C, Davis TP, Ronaldson PT. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 35504656 DOI: 10.1124/dmd.121.000781 |
0.628 |
|
| 2022 |
Nilles KL, Williams EI, Betterton RD, Davis TP, Ronaldson PT. Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke. International Journal of Molecular Sciences. 23. PMID 35163820 DOI: 10.3390/ijms23031898 |
0.761 |
|
| 2021 |
Betterton RD, Davis TP, Ronaldson PT. Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery. Handbook of Experimental Pharmacology. PMID 33674914 DOI: 10.1007/164_2021_448 |
0.638 |
|
| 2020 |
Ronaldson PT, Brzica H, Abdullahi W, Reilly BG, Davis TP. . The Journal of Pharmacology and Experimental Therapeutics. PMID 33168642 DOI: 10.1124/jpet.120.000267 |
0.519 |
|
| 2020 |
Ronaldson PT, Davis TP. Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic opportunity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20951995. PMID 32928017 DOI: 10.1177/0271678X20951995 |
0.531 |
|
| 2020 |
Lochhead JJ, Yang J, Ronaldson PT, Davis TP. Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders. Frontiers in Physiology. 11: 914. PMID 32848858 DOI: 10.3389/Fphys.2020.00914 |
0.741 |
|
| 2020 |
Williams EI, Betterton RD, Davis TP, Ronaldson PT. Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke. Pharmaceutics. 12. PMID 32075088 DOI: 10.3390/pharmaceutics12020154 |
0.688 |
|
| 2020 |
Ronaldson PT, Lochhead JJ, Davis TP. Abstract TP121: Organic Anion Transporting Polypeptide (Oatp)-Mediated Transport is Required for Statin-Induced Neuroprotection: A Role for Blood-Brain Barrier Transporters in Stroke Treatment Stroke. 51. DOI: 10.1161/STR.51.SUPPL_1.TP121 |
0.524 |
|
| 2019 |
Lochhead JJ, Kellohen KL, Ronaldson PT, Davis TP. Distribution of insulin in trigeminal nerve and brain after intranasal administration. Scientific Reports. 9: 2621. PMID 30796294 DOI: 10.1038/S41598-019-39191-5 |
0.649 |
|
| 2018 |
Yang J, Reilly BG, Davis TP, Ronaldson PT. Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity. Pharmaceutics. 10. PMID 30340346 DOI: 10.3390/pharmaceutics10040192 |
0.466 |
|
| 2018 |
Abdullahi W, Brzica H, Hirsch NA, Reilly BG, Ronaldson PT. Functional Expression of Organic Anion Transporting Polypeptide 1a4 Is Regulated by Transforming Growth Factor-/Activin Receptor-like Kinase 1 Signaling at the Blood-Brain Barrier. Molecular Pharmacology. 94: 1321-1333. PMID 30262595 DOI: 10.1124/mol.118.112912 |
0.488 |
|
| 2018 |
Brzica H, Abdullahi W, Reilly BG, Ronaldson PT. Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in Sprague-Dawley rats. Fluids and Barriers of the Cns. 15: 25. PMID 30208928 DOI: 10.1186/s12987-018-0110-9 |
0.482 |
|
| 2018 |
Abdullahi W, Tripathi D, Ronaldson PT. Blood-Brain Barrier Dysfunction in Ischemic Stroke: Targeting Tight Junctions and Transporters for Vascular Protection. American Journal of Physiology. Cell Physiology. PMID 29949404 DOI: 10.1152/ajpcell.00095.2018 |
0.584 |
|
| 2018 |
Brzica H, Abdullahi W, Reilly BG, Ronaldson PT. A Simple and Reproducible Method to Prepare Membrane Samples from Freshly Isolated Rat Brain Microvessels. Journal of Visualized Experiments : Jove. PMID 29782001 DOI: 10.3791/57698 |
0.34 |
|
| 2017 |
Brzica H, Abdullahi W, Ibbotson K, Ronaldson PT. Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke. Journal of Central Nervous System Disease. 9: 1179573517693802. PMID 28469523 DOI: 10.1177/1179573517693802 |
0.588 |
|
| 2017 |
Abdullahi W, Davis TP, Ronaldson PT. Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery? The Aaps Journal. PMID 28447295 DOI: 10.1208/s12248-017-0081-9 |
0.626 |
|
| 2017 |
Abdullahi W, Brzica H, Ibbotson K, Davis TP, Ronaldson PT. Bone morphogenetic protein-9 increases the functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier via the activin receptor-like kinase-1 receptor. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17702916. PMID 28387157 DOI: 10.1177/0271678X17702916 |
0.601 |
|
| 2017 |
Lochhead JJ, Ronaldson PT, Davis TP. Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System. The Aaps Journal. PMID 28353217 DOI: 10.1208/S12248-017-0076-6 |
0.756 |
|
| 2017 |
Ibbotson K, Yell J, Ronaldson PT. Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress. Fluids and Barriers of the Cns. 14: 6. PMID 28298215 DOI: 10.1186/s12987-017-0055-4 |
0.302 |
|
| 2017 |
Ronaldson PT, Davis TP. Mechanisms of Endothelial Injury and Blood–Brain Barrier Dysfunction in Stroke Primer On Cerebrovascular Diseases. 220-226. DOI: 10.1016/B978-0-12-803058-5.00045-X |
0.655 |
|
| 2016 |
Ronaldson PT, Bauer B, El-Kattan AF, Shen H, Salphati L, Louie SW. Highlights from the AAPS/ITC Joint Workshop on Drug Transporters in ADME: From the Bench to the Bedside - Clinical Pharmacology Considerations. Clinical Pharmacology and Therapeutics. PMID 27500791 DOI: 10.1002/cpt.439 |
0.34 |
|
| 2015 |
Ronaldson PT, Davis TP. Targeting transporters: Promoting blood-brain barrier repair in response to oxidative stress injury. Brain Research. PMID 25796436 DOI: 10.1016/j.brainres.2015.03.018 |
0.603 |
|
| 2014 |
Thompson BJ, Ronaldson PT. Drug delivery to the ischemic brain. Advances in Pharmacology (San Diego, Calif.). 71: 165-202. PMID 25307217 DOI: 10.1016/bs.apha.2014.06.013 |
0.591 |
|
| 2014 |
Sanchez-Covarrubias L, Slosky LM, Thompson BJ, Zhang Y, Laracuente ML, DeMarco KM, Ronaldson PT, Davis TP. P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac. Plos One. 9: e88516. PMID 24520393 DOI: 10.1371/Journal.Pone.0088516 |
0.493 |
|
| 2014 |
Thompson BJ, Sanchez-Covarrubias L, Slosky LM, Zhang Y, Laracuente ML, Ronaldson PT. Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood-brain barrier: relevance to CNS drug delivery. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 699-707. PMID 24473481 DOI: 10.1038/Jcbfm.2014.4 |
0.47 |
|
| 2014 |
Sanchez-Covarrubias L, Slosky LM, Thompson BJ, Davis TP, Ronaldson PT. Transporters at CNS barrier sites: obstacles or opportunities for drug delivery? Current Pharmaceutical Design. 20: 1422-49. PMID 23789948 DOI: 10.2174/13816128113199990463 |
0.639 |
|
| 2014 |
Ronaldson PT. Targeting transporters for CNS drug delivery. Current Pharmaceutical Design. 20: 1419-21. PMID 23789947 DOI: 10.2174/13816128113199990469 |
0.41 |
|
| 2013 |
Ronaldson PT, Davis TP. Gabapentin and diclofenac reduce opioid consumption in patients undergoing tonsillectomy: a result of altered CNS drug delivery? Archives of Trauma Research. 2: 97-8. PMID 24396803 DOI: 10.5812/atr.11011 |
0.495 |
|
| 2013 |
Slosky LM, Thompson BJ, Sanchez-Covarrubias L, Zhang Y, Laracuente ML, Vanderah TW, Ronaldson PT, Davis TP. Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism. Molecular Pharmacology. 84: 774-86. PMID 24019224 DOI: 10.1124/Mol.113.086298 |
0.505 |
|
| 2013 |
Ronaldson PT, Davis TP. Targeted drug delivery to treat pain and cerebral hypoxia. Pharmacological Reviews. 65: 291-314. PMID 23343976 DOI: 10.1124/pr.112.005991 |
0.638 |
|
| 2012 |
McCaffrey G, Staatz WD, Sanchez-Covarrubias L, Finch JD, Demarco K, Laracuente ML, Ronaldson PT, Davis TP. P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia. Journal of Neurochemistry. 122: 962-75. PMID 22716933 DOI: 10.1111/j.1471-4159.2012.07831.x |
0.462 |
|
| 2012 |
Ronaldson PT, Davis TP. Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke. Current Pharmaceutical Design. 18: 3624-44. PMID 22574987 DOI: 10.2174/138161212802002625 |
0.693 |
|
| 2012 |
Lochhead JJ, McCaffrey G, Sanchez-Covarrubias L, Finch JD, Demarco KM, Quigley CE, Davis TP, Ronaldson PT. Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain. American Journal of Physiology. Heart and Circulatory Physiology. 302: H582-93. PMID 22081706 DOI: 10.1152/Ajpheart.00889.2011 |
0.718 |
|
| 2011 |
Ronaldson PT, Davis TP. Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery. Therapeutic Delivery. 2: 1015-41. PMID 22468221 DOI: 10.4155/tde.11.67 |
0.62 |
|
| 2011 |
Ronaldson PT, Finch JD, Demarco KM, Quigley CE, Davis TP. Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier. The Journal of Pharmacology and Experimental Therapeutics. 336: 827-39. PMID 21131267 DOI: 10.1124/jpet.110.174151 |
0.533 |
|
| 2010 |
Witt KA, Ronaldson PT, Sandoval KE, Davis TP. CNS delivery of peptides across the bbb using the dual-artery in situ brain perfusion model Neuromethods. 45: 233-247. DOI: 10.1007/978-1-60761-529-3_11 |
0.692 |
|
| 2009 |
Ronaldson PT, Demarco KM, Sanchez-Covarrubias L, Solinsky CM, Davis TP. Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1084-98. PMID 19319146 DOI: 10.1038/jcbfm.2009.32 |
0.398 |
|
| 2009 |
Zastre JA, Chan GNY, Ronaldson PT, Ramaswamy M, Couraud PO, Romero IA, Weksler B, Bendayan M, Bendayan R. Up-regulation of p-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line Journal of Neuroscience Research. 87: 1023-1036. PMID 18855943 DOI: 10.1002/jnr.21898 |
0.372 |
|
| 2008 |
Ronaldson PT, Persidsky Y, Bendayan R. Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection. Glia. 56: 1711-35. PMID 18649402 DOI: 10.1002/Glia.20725 |
0.368 |
|
| 2006 |
Bendayan R, Ronaldson PT, Gingras D, Bendayan M. In situ localization of P-glycoprotein (ABCB1) in human and rat brain Journal of Histochemistry and Cytochemistry. 54: 1159-1167. PMID 16801529 DOI: 10.1369/jhc.5A6870.2006 |
0.328 |
|
| 2004 |
Ronaldson PT, Lee G, Dallas S, Bendayan R. Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines. Pharmaceutical Research. 21: 811-8. PMID 15180339 DOI: 10.1023/B:PHAM.0000026433.27773.47 |
0.317 |
|
| 2004 |
Dallas S, Ronaldson PT, Bendayan M, Bendayan R. Multidrug resistance protein 1-mediated transport of saquinavir by microglia. Neuroreport. 15: 1183-6. PMID 15129170 DOI: 10.1097/00001756-200405190-00020 |
0.308 |
|
| 2002 |
Ronaldson PT, Bendayan R. Renal Drug Transport and Drug-Drug Interactions Journal of Pharmacy Practice. 15: 490-503. DOI: 10.1177/089719002237667 |
0.355 |
|
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