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Year Citation  Score
2018 Fribourg M, Logothetis DE, González-Maeso J, Sealfon SC, Galocha-Iragüen B, Las-Heras Andrés F, Brezina V. Correction: Elucidation of molecular kinetic schemes from macroscopic traces using system identification. Plos Computational Biology. 14: e1006539. PMID 30325915 DOI: 10.1371/journal.pcbi.1006539  0.72
2018 Delgado-Ramírez M, De Jesús-Pérez JJ, Aréchiga-Figueroa IA, Arreola J, Adney SK, Villalba-Galea CA, Logothetis DE, Rodríguez-Menchaca AA. Regulation of Kv2.1 channel inactivation by phosphatidylinositol 4,5-bisphosphate. Scientific Reports. 8: 1769. PMID 29379118 DOI: 10.1038/s41598-018-20280-w  0.52
2017 Fribourg M, Logothetis DE, González-Maeso J, Sealfon SC, Galocha-Iragüen B, Las-Heras Andrés F, Brezina V. Elucidation of molecular kinetic schemes from macroscopic traces using system identification. Plos Computational Biology. 13: e1005376. PMID 28192423 DOI: 10.1371/journal.pcbi.1005376  0.72
2016 Meng XY, Liu S, Cui M, Zhou R, Logothetis DE. The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel. Scientific Reports. 6: 29399. PMID 27439597 DOI: 10.1038/srep29399  0.76
2016 Younkin J, Gaitonde SA, Ellaithy A, Vekariya RH, Baki L, Moreno JL, Shah S, Drossopoulos P, Hideshima KS, Eltit JM, González-Maeso J, Logothetis DE, Dukat M, Glennon RA. Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists. Acs Chemical Neuroscience. PMID 27385190 DOI: 10.1021/acschemneuro.6b00162  0.76
2016 Deng W, Mahajan R, Baumgarten CM, Logothetis DE. The ICl,swell inhibitor DCPIB blocks Kir channels that possess weak affinity for PIP2. Pflugers Archiv : European Journal of Physiology. PMID 26837888 DOI: 10.1007/s00424-016-1794-9  0.76
2016 Baki L, Fribourg M, Younkin J, Eltit JM, Moreno JL, Park G, Vysotskaya Z, Narahari A, Sealfon SC, Gonzalez-Maeso J, Logothetis DE. Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells. Pflugers Archiv : European Journal of Physiology. PMID 26780666 DOI: 10.1007/s00424-015-1780-7  0.76
2016 Moreno JL, Miranda-Azpiazu P, García-Bea A, Younkin J, Cui M, Kozlenkov A, Ben-Ezra A, Voloudakis G, Fakira AK, Baki L, Ge Y, Georgakopoulos A, Morón JA, Milligan G, López-Giménez JF, ... ... Logothetis DE, et al. Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia. Science Signaling. 9: ra5. PMID 26758213 DOI: 10.1126/scisignal.aab0467  0.76
2015 Tang QY, Zhang FF, Xu J, Wang R, Chen J, Logothetis DE, Zhang Z. Epilepsy-Related Slack Channel Mutants Lead to Channel Over-Activity by Two Different Mechanisms. Cell Reports. PMID 26725113 DOI: 10.1016/j.celrep.2015.12.019  0.76
2015 Adney SK, Ha J, Meng XY, Kawano T, Logothetis DE. A Critical Gating Switch at a Modulatory Site in Neuronal Kir3 Channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14397-405. PMID 26490875 DOI: 10.1523/JNEUROSCI.1415-15.2015  0.76
2015 Logothetis DE, Mahajan R, Adney SK, Ha J, Kawano T, Meng XY, Cui M. Unifying Mechanism of Controlling Kir3 Channel Activity by G Proteins and Phosphoinositides. International Review of Neurobiology. 123: 1-26. PMID 26422981 DOI: 10.1016/bs.irn.2015.05.013  0.76
2015 Ellaithy A, Younkin J, González-Maeso J, Logothetis DE. Positive allosteric modulators of metabotropic glutamate 2 receptors in schizophrenia treatment. Trends in Neurosciences. 38: 506-16. PMID 26148747 DOI: 10.1016/j.tins.2015.06.002  0.76
2015 Li J, Lü S, Liu Y, Pang C, Chen Y, Zhang S, Yu H, Long M, Zhang H, Logothetis DE, Zhan Y, An H. Identification of the Conformational transition pathway in PIP2 Opening Kir Channels. Scientific Reports. 5: 11289. PMID 26063437 DOI: 10.1038/srep11289  0.76
2015 Tang QY, Larry T, Hendra K, Yamamoto E, Bell J, Cui M, Logothetis DE, Boland LM. Mutations in Nature Conferred a High Affinity Phosphatidylinositol 4,5-Bisphosphate-binding Site in Vertebrate Inwardly Rectifying Potassium Channels. The Journal of Biological Chemistry. 290: 16517-29. PMID 25957411 DOI: 10.1074/jbc.M115.640409  0.76
2015 Mastorodemos V, Kanavouras K, Sundaram S, Providaki M, Petraki Z, Kokkinidis M, Zaganas I, Logothetis DE, Plaitakis A. Side-chain interactions in the regulatory domain of human glutamate dehydrogenase determine basal activity and regulation. Journal of Neurochemistry. 133: 73-82. PMID 25620628 DOI: 10.1111/jnc.13019  0.76
2015 Logothetis DE, Petrou VI, Zhang M, Mahajan R, Meng XY, Adney SK, Cui M, Baki L. Phosphoinositide control of membrane protein function: a frontier led by studies on ion channels. Annual Review of Physiology. 77: 81-104. PMID 25293526 DOI: 10.1146/annurev-physiol-021113-170358  0.76
2014 Hatcher-Solis C, Fribourg M, Spyridaki K, Younkin J, Ellaithy A, Xiang G, Liapakis G, Gonzalez-Maeso J, Zhang H, Cui M, Logothetis DE. G protein-coupled receptor signaling to Kir channels in Xenopus oocytes. Current Pharmaceutical Biotechnology. 15: 987-95. PMID 25374032  0.76
2014 Li J, Xie X, Liu J, Yu H, Zhang S, Zhan Y, Zhang H, Logothetis DE, An H. Lack of negatively charged residues at the external mouth of Kir2.2 channels enable the voltage-dependent block by external Mg2+. Plos One. 9: e111372. PMID 25350118 DOI: 10.1371/journal.pone.0111372  0.76
2014 Zhang M, Meng XY, Cui M, Pascal JM, Logothetis DE, Zhang JF. Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex. Nature Chemical Biology. 10: 753-9. PMID 25108821 DOI: 10.1038/nchembio.1592  0.76
2014 Spyridaki K, Matsoukas MT, Cordomi A, Gkountelias K, Papadokostaki M, Mavromoustakos T, Logothetis DE, Margioris AN, Pardo L, Liapakis G. Structural-functional analysis of the third transmembrane domain of the corticotropin-releasing factor type 1 receptor: role in activation and allosteric antagonism. The Journal of Biological Chemistry. 289: 18966-77. PMID 24838244 DOI: 10.1074/jbc.M113.544460  0.76
2014 Tang QY, Zhang Z, Meng XY, Cui M, Logothetis DE. Structural determinants of phosphatidylinositol 4,5-bisphosphate (PIP2) regulation of BK channel activity through the RCK1 Ca2+ coordination site. The Journal of Biological Chemistry. 289: 18860-72. PMID 24778177 DOI: 10.1074/jbc.M113.538033  0.76
2014 Hatcher-Solis C, Fribourg M, Spyridaki K, Younkin J, Ellaithy A, Xiang G, Liapakis G, Gonzalez-Maeso J, Zhang H, Cui M, Logothetis DE. G protein-coupled receptor signaling to kir channels in xenopus oocytes 1 Current Pharmaceutical Biotechnology. 15: 987-995.  0.76
2013 Rosenhouse-Dantsker A, Noskov S, Durdagi S, Logothetis DE, Levitan I. Identification of novel cholesterol-binding regions in Kir2 channels. The Journal of Biological Chemistry. 288: 31154-64. PMID 24019518 DOI: 10.1074/jbc.M113.496117  0.76
2013 Mahajan R, Ha J, Zhang M, Kawano T, Kozasa T, Logothetis DE. A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels. Science Signaling. 6: ra69. PMID 23943609 DOI: 10.1126/scisignal.2004075  0.76
2013 Rosenhouse-Dantsker A, Noskov S, Logothetis DE, Levitan I. Cholesterol sensitivity of KIR2.1 depends on functional inter-links between the N and C termini. Channels (Austin, Tex.). 7: 303-12. PMID 23807091 DOI: 10.4161/chan.25437  0.76
2013 Zhang Z, Tang QY, Alaimo JT, Davies AG, Bettinger JC, Logothetis DE. SLO-2 isoforms with unique Ca(2+) - and voltage-dependence characteristics confer sensitivity to hypoxia in C. elegans. Channels (Austin, Tex.). 7: 194-205. PMID 23590941 DOI: 10.4161/chan.24492  0.76
2013 Zhou L, Logothetis DE. The where and how of PIP regulation of cone photoreceptor CNG channels. The Journal of General Physiology. 141: 403-7. PMID 23530135 DOI: 10.1085/jgp.201310981  0.76
2013 Logothetis DE, Mahajan R, VanHook AM. Science signaling podcast: 13 August 2013 Science Signaling. 6. DOI: 10.1126/scisignal.2004566  0.76
2012 Rodríguez-Menchaca AA, Adney SK, Zhou L, Logothetis DE. Dual Regulation of Voltage-Sensitive Ion Channels by PIP(2). Frontiers in Pharmacology. 3: 170. PMID 23055973 DOI: 10.3389/fphar.2012.00170  0.76
2012 An HL, Lü SQ, Li JW, Meng XY, Zhan Y, Cui M, Long M, Zhang HL, Logothetis DE. The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels. The Journal of Biological Chemistry. 287: 42278-87. PMID 23033482 DOI: 10.1074/jbc.M112.418640  0.76
2012 Rosenhouse-Dantsker A, Noskov S, Han H, Adney SK, Tang QY, Rodríguez-Menchaca AA, Kowalsky GB, Petrou VI, Osborn CV, Logothetis DE, Levitan I. Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)). The Journal of Biological Chemistry. 287: 40266-78. PMID 22995912 DOI: 10.1074/jbc.M111.336339  0.76
2012 Rodriguez-Menchaca AA, Adney SK, Tang QY, Meng XY, Rosenhouse-Dantsker A, Cui M, Logothetis DE. PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4-S5 linker. Proceedings of the National Academy of Sciences of the United States of America. 109: E2399-408. PMID 22891352 DOI: 10.1073/pnas.1207901109  0.76
2012 Meng XY, Zhang HX, Logothetis DE, Cui M. The molecular mechanism by which PIP(2) opens the intracellular G-loop gate of a Kir3.1 channel. Biophysical Journal. 102: 2049-59. PMID 22824268 DOI: 10.1016/j.bpj.2012.03.050  0.76
2012 Wells GD, Tang QY, Heler R, Tompkins-MacDonald GJ, Pritchard EN, Leys SP, Logothetis DE, Boland LM. A unique alkaline pH-regulated and fatty acid-activated tandem pore domain potassium channel (K₂P) from a marine sponge. The Journal of Experimental Biology. 215: 2435-44. PMID 22723483 DOI: 10.1242/jeb.066233  0.76
2012 Deng W, Bukiya AN, Rodríguez-Menchaca AA, Zhang Z, Baumgarten CM, Logothetis DE, Levitan I, Rosenhouse-Dantsker A. Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4,5-bisphosphate and Gβγ. The Journal of Biological Chemistry. 287: 4925-35. PMID 22174416 DOI: 10.1074/jbc.M111.306134  0.76
2011 Fribourg M, Moreno JL, Holloway T, Provasi D, Baki L, Mahajan R, Park G, Adney SK, Hatcher C, Eltit JM, Ruta JD, Albizu L, Li Z, Umali A, Shim J, ... ... Logothetis DE, et al. Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs. Cell. 147: 1011-23. PMID 22118459 DOI: 10.1016/j.cell.2011.09.055  0.76
2011 Rosenhouse-Dantsker A, Logothetis DE, Levitan I. Cholesterol sensitivity of KIR2.1 is controlled by a belt of residues around the cytosolic pore. Biophysical Journal. 100: 381-9. PMID 21244834 DOI: 10.1016/j.bpj.2010.11.086  0.76
2011 Michailidis IE, Rusinova R, Georgakopoulos A, Chen Y, Iyengar R, Robakis NK, Logothetis DE, Baki L. Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation. PflüGers Archiv : European Journal of Physiology. 461: 387-97. PMID 21107857 DOI: 10.1007/s00424-010-0904-3  0.76
2010 Styer AM, Mirshahi UL, Wang C, Girard L, Jin T, Logothetis DE, Mirshahi T. G protein {beta}{gamma} gating confers volatile anesthetic inhibition to Kir3 channels. The Journal of Biological Chemistry. 285: 41290-9. PMID 21044958 DOI: 10.1074/jbc.M110.178541  0.76
2010 Leal-Pinto E, Gómez-Llorente Y, Sundaram S, Tang QY, Ivanova-Nikolova T, Mahajan R, Baki L, Zhang Z, Chavez J, Ubarretxena-Belandia I, Logothetis DE. Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayers. The Journal of Biological Chemistry. 285: 39790-800. PMID 20937804 DOI: 10.1074/jbc.M110.151373  0.76
2010 Zhang Z, Rosenhouse-Dantsker A, Tang QY, Noskov S, Logothetis DE. The RCK2 domain uses a coordination site present in Kir channels to confer sodium sensitivity to Slo2.2 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7554-62. PMID 20519529 DOI: 10.1523/JNEUROSCI.0525-10.2010  0.76
2010 Logothetis DE, Petrou VI, Adney SK, Mahajan R. Channelopathies linked to plasma membrane phosphoinositides. PflüGers Archiv : European Journal of Physiology. 460: 321-41. PMID 20396900 DOI: 10.1007/s00424-010-0828-y  0.76
2010 Tang QY, Zhang Z, Xia J, Ren D, Logothetis DE. Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibition. The Journal of Biological Chemistry. 285: 19259-66. PMID 20392696 DOI: 10.1074/jbc.M109.100156  0.76
2010 Lupyan D, Mezei M, Logothetis DE, Osman R. A molecular dynamics investigation of lipid bilayer perturbation by PIP2. Biophysical Journal. 98: 240-7. PMID 20338845 DOI: 10.1016/j.bpj.2009.09.063  0.76
2010 Rosenhouse-Dantsker A, Leal-Pinto E, Logothetis DE, Levitan I. Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loop. Channels (Austin, Tex.). 4: 63-6. PMID 19923917  0.76
2009 Mo G, Bernier LP, Zhao Q, Chabot-Doré AJ, Ase AR, Logothetis D, Cao CQ, Séguéla P. Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors. Molecular Pain. 5: 47. PMID 19671169 DOI: 10.1186/1744-8069-5-47  0.76
2009 Geng X, Du XN, Rusinova R, Liu BY, Li F, Zhang X, Chen XJ, Logothetis DE, Zhang HL. Specificity of Gbetagamma signaling depends on Galpha subunit coupling with G-protein-sensitive K(+) channels. Pharmacology. 84: 82-90. PMID 19590257 DOI: 10.1159/000227772  0.76
2009 Epshtein Y, Chopra AP, Rosenhouse-Dantsker A, Kowalsky GB, Logothetis DE, Levitan I. Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol. Proceedings of the National Academy of Sciences of the United States of America. 106: 8055-60. PMID 19416905 DOI: 10.1073/pnas.0809847106  0.76
2009 Rusinova R, Shen YM, Dolios G, Padovan J, Yang H, Kirchberger M, Wang R, Logothetis DE. Mass spectrometric analysis reveals a functionally important PKA phosphorylation site in a Kir3 channel subunit. PflüGers Archiv : European Journal of Physiology. 458: 303-14. PMID 19151997 DOI: 10.1007/s00424-008-0628-9  0.76
2008 Bernier LP, Ase AR, Chevallier S, Blais D, Zhao Q, Boué-Grabot E, Logothetis D, Séguéla P. Phosphoinositides regulate P2X4 ATP-gated channels through direct interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12938-45. PMID 19036987 DOI: 10.1523/JNEUROSCI.3038-08.2008  0.76
2008 Rosenhouse-Dantsker A, Sui JL, Zhao Q, Rusinova R, Rodríguez-Menchaca AA, Zhang Z, Logothetis DE. A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P(2). Nature Chemical Biology. 4: 624-31. PMID 18794864 DOI: 10.1038/nchembio.112  0.76
2008 Jin T, Sui JL, Rosenhouse-Dantsker A, Chan KW, Jan LY, Logothetis DE. Stoichiometry of Kir channels with phosphatidylinositol bisphosphate. Channels (Austin, Tex.). 2: 19-33. PMID 18690051 DOI: 10.4161/chan.2.1.5942  0.76
2008 Bernier LP, Ase AR, Tong X, Hamel E, Blais D, Zhao Q, Logothetis DE, Séguéla P. Direct modulation of P2X1 receptor-channels by the lipid phosphatidylinositol 4,5-bisphosphate. Molecular Pharmacology. 74: 785-92. PMID 18523136 DOI: 10.1124/mol.108.047019  0.76
2007 Zhao Q, Yang M, Ting AT, Logothetis DE. PIP(2) regulates the ionic current of P2X receptors and P2X(7) receptor-mediated cell death. Channels (Austin, Tex.). 1: 46-55. PMID 19151591 DOI: 10.4161/chan.3914  0.76
2007 Rosenhouse-Dantsker A, Logothetis DE. Potassium channel gating in the absence of the highly conserved glycine of the inner transmembrane helix. Channels (Austin, Tex.). 1: 189-97. PMID 18690025  0.76
2007 Lopes CM, Remon JI, Matavel A, Sui JL, Keselman I, Medei E, Shen Y, Rosenhouse-Dantsker A, Rohacs T, Logothetis DE. Protein kinase A modulates PLC-dependent regulation and PIP2-sensitivity of K+ channels. Channels (Austin, Tex.). 1: 124-34. PMID 18690021  0.76
2007 Keselman I, Fribourg M, Felsenfeld DP, Logothetis DE. Mechanism of PLC-mediated Kir3 current inhibition. Channels (Austin, Tex.). 1: 113-23. PMID 18690019  0.76
2007 Rusinova R, Mirshahi T, Logothetis DE. Specificity of Gbetagamma signaling to Kir3 channels depends on the helical domain of pertussis toxin-sensitive Galpha subunits. The Journal of Biological Chemistry. 282: 34019-30. PMID 17872944 DOI: 10.1074/jbc.M704928200  0.76
2007 Gibor G, Yakubovich D, Rosenhouse-Dantsker A, Peretz A, Schottelndreier H, Seebohm G, Dascal N, Logothetis DE, Paas Y, Attali B. An inactivation gate in the selectivity filter of KCNQ1 potassium channels. Biophysical Journal. 93: 4159-72. PMID 17704175 DOI: 10.1529/biophysj.107.107987  0.76
2007 Logothetis DE, Nilius B. Dynamic changes in phosphoinositide levels control ion channel activity. PflüGers Archiv : European Journal of Physiology. 455: 1-3. PMID 17641911 DOI: 10.1007/s00424-007-0311-6  0.76
2007 Rosenhouse-Dantsker A, Logothetis DE. Molecular characteristics of phosphoinositide binding. PflüGers Archiv : European Journal of Physiology. 455: 45-53. PMID 17588168 DOI: 10.1007/s00424-007-0291-6  0.76
2007 Logothetis DE, Jin T, Lupyan D, Rosenhouse-Dantsker A. Phosphoinositide-mediated gating of inwardly rectifying K(+) channels. PflüGers Archiv : European Journal of Physiology. 455: 83-95. PMID 17520276 DOI: 10.1007/s00424-007-0276-5  0.76
2007 Michailidis IE, Helton TD, Petrou VI, Mirshahi T, Ehlers MD, Logothetis DE. Phosphatidylinositol-4,5-bisphosphate regulates NMDA receptor activity through alpha-actinin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5523-32. PMID 17507574 DOI: 10.1523/JNEUROSCI.4378-06.2007  0.76
2007 Logothetis DE, Lupyan D, Rosenhouse-Dantsker A. Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding. The Journal of Physiology. 582: 953-65. PMID 17495041 DOI: 10.1113/jphysiol.2007.133157  0.76
2007 Zhao Q, Logothetis DE, Séguéla P. Regulation of ATP-gated P2X receptors by phosphoinositides. PflüGers Archiv : European Journal of Physiology. 455: 181-5. PMID 17479282 DOI: 10.1007/s00424-007-0271-x  0.76
2006 Pyo RT, Sui J, Dhume A, Palomeque J, Blaxall BC, Diaz G, Tunstead J, Logothetis DE, Hajjar RJ, Schecter AD. CXCR4 modulates contractility in adult cardiac myocytes. Journal of Molecular and Cellular Cardiology. 41: 834-44. PMID 17010372 DOI: 10.1016/j.yjmcc.2006.08.008  0.76
2006 Ishii Y, Pirkmaier A, Alvarez JV, Frank DA, Keselman I, Logothetis D, Mandeli J, O'Connell MJ, Waxman S, Germain D. Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model. Journal of the National Cancer Institute. 98: 1238-47. PMID 16954476 DOI: 10.1093/jnci/djj334  0.76
2006 Rosenhouse-Dantsker A, Logothetis DE. New roles for a key glycine and its neighboring residue in potassium channel gating. Biophysical Journal. 91: 2860-73. PMID 16877518 DOI: 10.1529/biophysj.105.080242  0.76
2006 Mirshahi T, Logothetis DE, Rosenhouse-Dantsker A. Hydrogen-bonding dynamics between adjacent blades in G-protein beta-subunit regulates GIRK channel activation. Biophysical Journal. 90: 2776-85. PMID 16428273 DOI: 10.1529/biophysj.105.069302  0.76
2005 Rohács T, Lopes CM, Michailidis I, Logothetis DE. PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain. Nature Neuroscience. 8: 626-34. PMID 15852009 DOI: 10.1038/nn1451  0.76
2005 Lopes CM, Rohács T, Czirják G, Balla T, Enyedi P, Logothetis DE. PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels. The Journal of Physiology. 564: 117-29. PMID 15677683 DOI: 10.1113/jphysiol.2004.081935  0.76
2004 Scott DB, Michailidis I, Mu Y, Logothetis D, Ehlers MD. Endocytosis and degradative sorting of NMDA receptors by conserved membrane-proximal signals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7096-109. PMID 15306643 DOI: 10.1523/JNEUROSCI.0780-04.2004  0.76
2004 Du X, Zhang H, Lopes C, Mirshahi T, Rohacs T, Logothetis DE. Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators. The Journal of Biological Chemistry. 279: 37271-81. PMID 15155739 DOI: 10.1074/jbc.M403413200  0.76
2004 Mirshahi T, Logothetis DE. Molecular determinants responsible for differential cellular distribution of G protein-gated inwardly rectifying K+ channels. The Journal of Biological Chemistry. 279: 11890-7. PMID 14703518 DOI: 10.1074/jbc.M313322200  0.76
2003 Peng L, Mirshahi T, Zhang H, Hirsch JP, Logothetis DE. Critical determinants of the G protein gamma subunits in the Gbetagamma stimulation of G protein-activated inwardly rectifying potassium (GIRK) channel activity. The Journal of Biological Chemistry. 278: 50203-11. PMID 12975366 DOI: 10.1074/jbc.M308299200  0.76
2003 Mirshahi T, Jin T, Logothetis DE. G beta gamma and KACh: old story, new insights. Science's Stke : Signal Transduction Knowledge Environment. 2003: PE32. PMID 12902568 DOI: 10.1126/stke.2003.194.pe32  0.76
2003 Chan KW, Zhang H, Logothetis DE. N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits. The Embo Journal. 22: 3833-43. PMID 12881418 DOI: 10.1093/emboj/cdg376  0.76
2003 Davila V, Yan Z, Craciun LC, Logothetis D, Sulzer D. D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5693-7. PMID 12843272  0.76
2003 Zhang H, Craciun LC, Mirshahi T, Rohács T, Lopes CM, Jin T, Logothetis DE. PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents. Neuron. 37: 963-75. PMID 12670425 DOI: 10.1016/S0896-6273(03)00125-9  0.76
2003 Rohács T, Lopes CM, Jin T, Ramdya PP, Molnár Z, Logothetis DE. Specificity of activation by phosphoinositides determines lipid regulation of Kir channels. Proceedings of the National Academy of Sciences of the United States of America. 100: 745-50. PMID 12525701 DOI: 10.1073/pnas.0236364100  0.76
2002 Mirshahi T, Logothetis DE. GIRK channel trafficking: different paths for different family members. Molecular Interventions. 2: 289-91. PMID 14993383 DOI: 10.1124/mi.2.5.289  0.76
2002 Jin T, Peng L, Mirshahi T, Rohacs T, Chan KW, Sanchez R, Logothetis DE. The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment. Molecular Cell. 10: 469-81. PMID 12408817 DOI: 10.1016/S1097-2765(02)00659-7  0.76
2002 Mirshahi T, Mittal V, Zhang H, Linder ME, Logothetis DE. Distinct sites on G protein beta gamma subunits regulate different effector functions. The Journal of Biological Chemistry. 277: 36345-50. PMID 12124391 DOI: 10.1074/jbc.M205359200  0.76
2002 Lopes CM, Zhang H, Rohacs T, Jin T, Yang J, Logothetis DE. Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies. Neuron. 34: 933-44. PMID 12086641 DOI: 10.1016/S0896-6273(02)00725-0  0.76
2002 He C, Yan X, Zhang H, Mirshahi T, Jin T, Huang A, Logothetis DE. Identification of critical residues controlling G protein-gated inwardly rectifying K(+) channel activity through interactions with the beta gamma subunits of G proteins. The Journal of Biological Chemistry. 277: 6088-96. PMID 11741896 DOI: 10.1074/jbc.M104851200  0.76
2002 Mirshahi T, Robillard L, Zhang H, Hébert TE, Logothetis DE. Gbeta residues that do not interact with Galpha underlie agonist-independent activity of K+ channels. The Journal of Biological Chemistry. 277: 7348-55. PMID 11707461 DOI: 10.1074/jbc.M109999200  0.76
2002 Rohács T, Lopes C, Mirshahi T, Jin T, Zhang H, Logothetis DE. Assaying phosphatidylinositol bisphosphate regulation of potassium channels. Methods in Enzymology. 345: 71-92. PMID 11665643 DOI: 10.1016/S0076-6879(02)45008-2  0.76
2001 Zhu L, Wu X, Wu MB, Chan KW, Logothetis DE, Thornhill WB. Cloning and characterization of G protein-gated inward rectifier K+ channel (GIRK1) isoforms from heart and brain. Journal of Molecular Neuroscience : Mn. 16: 21-32. PMID 11345517 DOI: 10.1385/JMN:16:1:21  0.76
2001 Hughes TE, Zhang H, Logothetis DE, Berlot CH. Visualization of a functional Galpha q-green fluorescent protein fusion in living cells. Association with the plasma membrane is disrupted by mutational activation and by elimination of palmitoylation sites, but not be activation mediated by receptors or AlF4-. The Journal of Biological Chemistry. 276: 4227-35. PMID 11076942 DOI: 10.1074/jbc.M007608200  0.76
2000 Kobrinsky E, Mirshahi T, Zhang H, Jin T, Logothetis DE. Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization. Nature Cell Biology. 2: 507-14. PMID 10934471 DOI: 10.1038/35019544  0.76
2000 Pabon A, Chan KW, Sui JL, Wu X, Logothetis DE, Thornhill WB. Glycosylation of GIRK1 at Asn119 and ROMK1 at Asn117 has different consequences in potassium channel function. The Journal of Biological Chemistry. 275: 30677-82. PMID 10889209 DOI: 10.1074/jbc.M005338200  0.76
1999 Rohács T, Chen J, Prestwich GD, Logothetis DE. Distinct specificities of inwardly rectifying K(+) channels for phosphoinositides. The Journal of Biological Chemistry. 274: 36065-72. PMID 10593888 DOI: 10.1074/jbc.274.51.36065  0.76
1999 Zhang H, He C, Yan X, Mirshahi T, Logothetis DE. Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions. Nature Cell Biology. 1: 183-8. PMID 10559906 DOI: 10.1038/11103  0.76
1999 Logothetis DE, Zhang H. Gating of G protein-sensitive inwardly rectifying K+ channels through phosphatidylinositol 4,5-bisphosphate. The Journal of Physiology. 520: 630. PMID 10545130 DOI: 10.1111/j.1469-7793.1999.00630.x  0.76
1999 Petit-Jacques J, Sui JL, Logothetis DE. Synergistic activation of G protein-gated inwardly rectifying potassium channels by the betagamma subunits of G proteins and Na(+) and Mg(2+) ions. The Journal of General Physiology. 114: 673-84. PMID 10532964 DOI: 10.1085/jgp.114.5.673  0.76
1999 Sui JL, Chan K, Langan MN, Vivaudou M, Logothetis DE. G protein gated potassium channels. Advances in Second Messenger and Phosphoprotein Research. 33: 179-201. PMID 10218119  0.76
1999 He C, Zhang H, Mirshahi T, Logothetis DE. Identification of a potassium channel site that interacts with G protein betagamma subunits to mediate agonist-induced signaling. The Journal of Biological Chemistry. 274: 12517-24. PMID 10212228 DOI: 10.1074/jbc.274.18.12517  0.76
1999 Sui JL, Petit-Jacques J, Logothetis DE. Chapter 18 Effect of Phosphatidylinositol Phosphates on the Gating of G-Protein-Activated K+Channels Current Topics in Membranes and Transport. 46: 337-354. DOI: 10.1016/S0070-2161(08)60934-X  0.76
1998 Kozak JA, Misler S, Logothetis DE. Characterization of a Ca2+-activated K+ current in insulin-secreting murine betaTC-3 cells. The Journal of Physiology. 509: 355-70. PMID 9575286  0.76
1998 Sui JL, Petit-Jacques J, Logothetis DE. Activation of the atrial KACh channel by the betagamma subunits of G proteins or intracellular Na+ ions depends on the presence of phosphatidylinositol phosphates. Proceedings of the National Academy of Sciences of the United States of America. 95: 1307-12. PMID 9448327 DOI: 10.1073/pnas.95.3.1307  0.76
1998 Kozak JA, Misler S, Logothetis DE. Characterization of a Ca2+-activated K+ current in insulin-secreting murine βTC-3 cells Journal of Physiology. 509: 355-370. DOI: 10.1111/j.1469-7793.1998.355bn.x  0.76
1997 Vivaudou M, Chan KW, Sui JL, Jan LY, Reuveny E, Logothetis DE. Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants. The Journal of Biological Chemistry. 272: 31553-60. PMID 9395492 DOI: 10.1074/jbc.272.50.31553  0.76
1997 Kozak JA, Logothetis DE. A calcium-dependent chloride current in insulin-secreting beta TC-3 cells. PflüGers Archiv : European Journal of Physiology. 433: 679-90. PMID 9049157 DOI: 10.1007/s004240050332  0.76
1997 Chan KW, Sui JL, Vivaudou M, Logothetis DE. Specific regions of heteromeric subunits involved in enhancement of G protein-gated K+ channel activity. The Journal of Biological Chemistry. 272: 6548-55. PMID 9045681 DOI: 10.1074/jbc.272.10.6548  0.76
1996 Chan KW, Sui JL, Vivaudou M, Logothetis DE. Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit. Proceedings of the National Academy of Sciences of the United States of America. 93: 14193-8. PMID 8943083 DOI: 10.1073/pnas.93.24.14193  0.76
1996 Sui JL, Chan KW, Logothetis DE. Na+ activation of the muscarinic K+ channel by a G-protein-independent mechanism. The Journal of General Physiology. 108: 381-91. PMID 8923264 DOI: 10.1085/jgp.108.5.381  0.76
1996 Chan KW, Langan MN, Sui JL, Kozak JA, Pabon A, Ladias JA, Logothetis DE. A recombinant inwardly rectifying potassium channel coupled to GTP-binding proteins. The Journal of General Physiology. 107: 381-97. PMID 8868049  0.76
1995 Chen J, DeVivo M, Dingus J, Harry A, Li J, Sui J, Carty DJ, Blank JL, Exton JH, Stoffel RH, Inglese J, Lefkowitz RJ, Logothetis DE, Hildebrandt JD, Iyengar R. A region of adenylyl cyclase 2 critical for regulation by G protein βγ subunits Science. 268: 1166-1169. PMID 7761832  0.76
1995 Welsh DK, Logothetis DE, Meister M, Reppert SM. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron. 14: 697-706. PMID 7718233 DOI: 10.1016/0896-6273(95)90214-7  0.76
1994 Castle NA, Fadous S, Logothetis DE, Wang GK. Aminopyridine block of Kv1.1 potassium channels expressed in mammalian cells and Xenopus oocytes. Molecular Pharmacology. 45: 1242-52. PMID 8022416  0.76
1994 Castle NA, Fadous SR, Logothetis DE, Wang GK. 4-Aminopyridine binding and slow inactivation are mutually exclusive in rat Kv1.1 and Shaker potassium channels. Molecular Pharmacology. 46: 1175-81. PMID 7808439  0.76
1993 Logothetis DE, Kammen BF, Lindpaintner K, Bisbas D, Nadal-Ginard B. Gating charge differences between two voltage-gated K+ channels are due to the specific charge content of their respective S4 regions. Neuron. 10: 1121-9. PMID 8318233 DOI: 10.1016/0896-6273(93)90060-5  0.76
1992 Logothetis DE, Movahedi S, Satler C, Lindpaintner K, Nadal-Ginard B. Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge. Neuron. 8: 531-40. PMID 1550676 DOI: 10.1016/0896-6273(92)90281-H  0.76
1990 Koren G, Liman ER, Logothetis DE, Nadal-Ginard B, Hess P. Gating mechanism of a cloned potassium channel expressed in frog oocytes and mammalian cells. Neuron. 4: 39-51. PMID 2310574 DOI: 10.1016/0896-6273(90)90442-I  0.76
1990 Boulos Z, Logothetis DE. Rats anticipate and discriminate between two daily feeding times. Physiology & Behavior. 48: 523-9. PMID 2075203 DOI: 10.1016/0031-9384(90)90294-E  0.76
1989 Plummer MR, Logothetis DE, Hess P. Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons. Neuron. 2: 1453-63. PMID 2560643 DOI: 10.1016/0896-6273(89)90191-8  0.76
1988 Clapham DE, Logothetis DE. Delayed rectifier K+ current in embryonic chick heart ventricle. The American Journal of Physiology. 254: H192-7. PMID 2827524  0.76
1988 Logothetis DE, Kim DH, Northup JK, Neer EJ, Clapham DE. Specificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 85: 5814-8. PMID 2457901  0.76
1987 Logothetis DE, Kurachi Y, Galper J, Neer EJ, Clapham DE. The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. Nature. 325: 321-6. PMID 2433589 DOI: 10.1038/325321a0  0.76
1987 Logothetis DE, Kurachi Y, Galper J, Neer EJ, Clapham DE. G protein opening of K+ channels Nature. 327: 22.  0.76
1987 Kurachi Y, Nakajima T, Sugimoto T, Clapham DE, Logothetis DE, Neer EJ, Galper J. On the molecular regulation of muscarinic K+ channel by GTP-binding proteins in cardiac atrial myocytes Biomedical Research. 8: 135-142.  0.76
1984 Logothetis DE, Boulos Z, Terman M. Lick rate and the circadian rhythm of water intake in the rat: Effects of deuterium oxide Annals of the New York Academy of Sciences. 614-617.  0.76
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