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Ranganath Mamidi, Ph.D. - Publications

Affiliations: 
2013 Veterinary and Comparative Anatomy, Pharmacology and Physiology Washington State University, Pullman, WA, United States 
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mamidi R, Holmes JB, Doh CY, Dominic KL, Madugula N, Stelzer JE. cMyBPC phosphorylation modulates the effect of omecamtiv mecarbil on myocardial force generation. The Journal of General Physiology. 153. PMID 33688929 DOI: 10.1085/jgp.202012816  0.377
2020 Li J, Mamidi R, Doh CY, Holmes JB, Bharambe N, Ramachandran R, Stelzer JE. AAV9 gene transfer of cMyBPC N-terminal domains ameliorates cardiomyopathy in cMyBPC deficient mice. Jci Insight. PMID 32750038 DOI: 10.1172/Jci.Insight.130182  0.423
2020 Holmes JB, Doh CY, Mamidi R, Li J, Stelzer JE. Strategies for targeting the cardiac sarcomere: avenues for novel drug discovery. Expert Opinion On Drug Discovery. 1-13. PMID 32067508 DOI: 10.1080/17460441.2020.1722637  0.369
2019 Doh CY, Li J, Mamidi R, Stelzer J. The HCM-causing Y235S cMyBPC mutation accelerates contractile function by altering C1 domain structure. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30611859 DOI: 10.1016/J.Bpj.2018.11.1443  0.478
2018 Mamidi R, Li J, Doh CY, Holmes JB, Stelzer JE. Lost in translation: Interpreting cardiac muscle mechanics data in clinical practice. Archives of Biochemistry and Biophysics. 662: 213-218. PMID 30576628 DOI: 10.1016/J.Abb.2018.12.021  0.482
2018 Mamidi R, Li J, Doh CY, Verma S, Stelzer JE. Impact of the Myosin Modulator Mavacamten on Force Generation and Cross-Bridge Behavior in a Murine Model of Hypercontractility. Journal of the American Heart Association. 7: e009627. PMID 30371160 DOI: 10.1161/Jaha.118.009627  0.348
2018 Li J, Gresham KS, Mamidi R, Doh CY, Wan X, Deschenes I, Stelzer JE. Sarcomere-based genetic enhancement of systolic cardiac function in a murine model of dilated cardiomyopathy. International Journal of Cardiology. PMID 30279005 DOI: 10.1016/J.Ijcard.2018.09.073  0.521
2017 Mamidi R, Li J, Gresham KS, Verma S, Doh CY, Li A, Lal S, Dos Remedios CG, Stelzer JE. Dose-Dependent Effects of the Myosin Activator Omecamtiv Mecarbil on Cross-Bridge Behavior and Force Generation in Failing Human Myocardium. Circulation. Heart Failure. 10. PMID 29030372 DOI: 10.1161/Circheartfailure.117.004257  0.344
2017 Mamidi R, Gresham KS, Li J, Stelzer JE. Cardiac myosin binding protein-C Ser(302) phosphorylation regulates cardiac β-adrenergic reserve. Science Advances. 3: e1602445. PMID 28345052 DOI: 10.1126/Sciadv.1602445  0.456
2017 Mamidi R, Gresham KS, Li J, Stelzer JE. Myosin Activator Omecamtiv Mecarbil Differentially Impacts the Contractile Properties of Skinned Myocardium from Failing and Donor Human Hearts Biophysical Journal. 112: 556a. DOI: 10.1016/J.Bpj.2016.11.3001  0.466
2016 Gresham KS, Mamidi R, Li J, Kwak H, Stelzer JE. Sarcomeric protein modification during adrenergic stress enhances cross-bridge kinetics and cardiac output. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00306.2016. PMID 27909224 DOI: 10.1152/Japplphysiol.00306.2016  0.49
2016 Mamidi R, Gresham KS, Verma S, Stelzer JE. Cardiac Myosin Binding Protein-C Phosphorylation Modulates Myofilament Length-Dependent Activation. Frontiers in Physiology. 7: 38. PMID 26913007 DOI: 10.3389/Fphys.2016.00038  0.458
2016 Mamidi R, Gresham KS, Stelzer JE. cMyBP-C Phosphorylation Modulates Sarcomere Length-Dependent Changes in Cardiac Muscle Contractile Function Biophysical Journal. 110: 525a-526a. DOI: 10.1016/J.Bpj.2015.11.2811  0.473
2015 Mamidi R, Gresham KS, Li A, dos Remedios CG, Stelzer JE. Molecular effects of the myosin activator omecamtiv mecarbil on contractile properties of skinned myocardium lacking cardiac myosin binding protein-C. Journal of Molecular and Cellular Cardiology. 85: 262-72. PMID 26100051 DOI: 10.1016/J.Yjmcc.2015.06.011  0.497
2015 Mamidi R, Gresham KS, Stelzer JE. Length-Dependent Contractile Dynamics are Blunted Upon Ablation of Cardiac Myosin Binding Protein-C Biophysical Journal. 108: 597a. DOI: 10.1016/J.Bpj.2014.11.3250  0.51
2014 Mamidi R, Gresham KS, Stelzer JE. Length-dependent changes in contractile dynamics are blunted due to cardiac myosin binding protein-C ablation. Frontiers in Physiology. 5: 461. PMID 25520665 DOI: 10.3389/Fphys.2014.00461  0.398
2014 Gresham KS, Mamidi R, Stelzer JE. The contribution of cardiac myosin binding protein-c Ser282 phosphorylation to the rate of force generation and in vivo cardiac contractility. The Journal of Physiology. 592: 3747-65. PMID 24951619 DOI: 10.1113/Jphysiol.2014.276022  0.525
2014 Mamidi R, Li J, Gresham KS, Stelzer JE. Cardiac myosin binding protein-C: a novel sarcomeric target for gene therapy. PflüGers Archiv : European Journal of Physiology. 466: 225-30. PMID 24310821 DOI: 10.1007/S00424-013-1412-Z  0.387
2013 Mamidi R, Muthuchamy M, Chandra M. Instability in the central region of tropomyosin modulates the function of its overlapping ends. Biophysical Journal. 105: 2104-13. PMID 24209855 DOI: 10.1016/J.Bpj.2013.09.026  0.635
2013 Mamidi R, Chandra M. Divergent effects of α- and β-myosin heavy chain isoforms on the N terminus of rat cardiac troponin T. The Journal of General Physiology. 142: 413-23. PMID 24043862 DOI: 10.1085/Jgp.201310971  0.68
2013 Mamidi R, Michael JJ, Muthuchamy M, Chandra M. Interplay between the overlapping ends of tropomyosin and the N terminus of cardiac troponin T affects tropomyosin states on actin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3848-59. PMID 23748972 DOI: 10.1096/Fj.13-232363  0.663
2013 Mamidi R, Mallampalli SL, Wieczorek DF, Chandra M. Identification of two new regions in the N-terminus of cardiac troponin T that have divergent effects on cardiac contractile function. The Journal of Physiology. 591: 1217-34. PMID 23207592 DOI: 10.1113/Jphysiol.2012.243394  0.692
2013 Mamidi R, Chandra M. Effects of the N-Terminus of Cardiac Troponin T on Contractile Activation Depend on the Type of Myosin Heavy Chain Isoform Biophysical Journal. 104: 482a-483a. DOI: 10.1016/J.Bpj.2012.11.2664  0.665
2012 Gollapudi SK, Mamidi R, Mallampalli SL, Chandra M. The N-terminal extension of cardiac troponin T stabilizes the blocked state of cardiac thin filament. Biophysical Journal. 103: 940-8. PMID 23009843 DOI: 10.1016/J.Bpj.2012.07.035  0.718
2012 Ford SJ, Mamidi R, Jimenez J, Tardiff JC, Chandra M. Effects of R92 mutations in mouse cardiac troponin T are influenced by changes in myosin heavy chain isoform. Journal of Molecular and Cellular Cardiology. 53: 542-51. PMID 22884844 DOI: 10.1016/J.Yjmcc.2012.07.018  0.731
2012 Mamidi R, Gollapudi SK, Mallampalli SL, Chandra M. Alanine or aspartic acid substitutions at serine23/24 of cardiac troponin I decrease thin filament activation, with no effect on crossbridge detachment kinetics. Archives of Biochemistry and Biophysics. 525: 1-8. PMID 22684024 DOI: 10.1016/J.Abb.2012.05.024  0.654
2012 Gollapudi SK, Mamidi R, Mallampalli S, Chandra M. Alterations in Hyper-Variable N-Terminal Region of Cardiac Troponin T Result in Diminished Cardiac Myofilament Function Biophysical Journal. 102: 561a. DOI: 10.1016/J.Bpj.2011.11.3056  0.724
2012 Michael JJ, Mamidi R, Gollapudi S, Tal L, Tardiff J, Chandra M. D230N Mutation in Tropomyosin and R92L Mutation in Cardiac Troponin T have Strikingly Different Impact on Calcium-Regulated Activation of Cardiac Myofilaments Biophysical Journal. 102: 358a. DOI: 10.1016/J.Bpj.2011.11.1956  0.685
2012 Mamidi R, Mallampalli S, Chandra M. Changes in the Myocardial Expression of Tropomyosin Isoforms Modulate Troponin T-Mediated Cardiac Thin Filament Activation Biophysical Journal. 102: 357a-358a. DOI: 10.1016/J.Bpj.2011.11.1954  0.681
2011 Ford SJ, Mamidi R, Jimenez JJ, Tardiff JC, Chandra M. Effects of R92 Mutations on Cardiac Contractile Function are Influenced by Changes in Myosin Heavy Chain Isoform Biophysical Journal. 100: 127a. DOI: 10.1016/J.Bpj.2010.12.898  0.731
2011 Mamidi R, Ford SJ, Chandra M. Deletions in the N-Terminus of Troponin T Reveal a Region Important for Ca2+- and Length-Dependent Cardiac Myofilament Activation Biophysical Journal. 100: 586a. DOI: 10.1016/J.Bpj.2010.12.3383  0.751
2011 Ford SJ, Mamidi R, Chandra M. Cardiac-Specific Helical Structure in Troponin I Imparts Unique, Cardiac-Specific Contractile Function Biophysical Journal. 100: 586a. DOI: 10.1016/J.Bpj.2010.12.3382  0.769
2010 Ford SJ, Chandra M, Mamidi R, Dong W, Campbell KB. Model representation of the nonlinear step response in cardiac muscle. The Journal of General Physiology. 136: 159-77. PMID 20660660 DOI: 10.1085/Jgp.201010467  0.735
2010 Ouyang Y, Mamidi R, Jayasundar JJ, Chandra M, Dong WJ. Structural and kinetic effects of PAK3 phosphorylation mimic of cTnI(S151E) on the cTnC-cTnI interaction in the cardiac thin filament. Journal of Molecular Biology. 400: 1036-45. PMID 20540949 DOI: 10.1016/J.Jmb.2010.06.007  0.626
2010 Jayasundar JJ, Mamidi R, Ouyang Y, Chandra M, Dong W. Effects of Pseudo-Phosphorylation of cTnI by P21 Activated Kinase-3 (PAK3) on Structure and Kinetics of Ca2+-Induced Cardiac Thin Filament Regulation Biophysical Journal. 98: 148a-149a. DOI: 10.1016/J.Bpj.2009.12.800  0.643
2010 Ford SJ, Mamidi R, Campbell KB, Chandra M. H2-Helical Region of Cardiac Troponin T Contributes to Length-Dependent Regulation of Cardiac Contractile Activation Biophysical Journal. 98: 358a. DOI: 10.1016/J.Bpj.2009.12.1933  0.733
2009 Kirk JA, MacGowan GA, Evans C, Smith SH, Warren CM, Mamidi R, Chandra M, Stewart AF, Solaro RJ, Shroff SG. Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I. Circulation Research. 105: 1232-9. PMID 19850940 DOI: 10.1161/Circresaha.109.205427  0.675
2009 Chandra M, Mamidi R, Ford S, Hidalgo C, Witt C, Ottenheijm C, Labeit S, Granzier H. Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost. The Journal of Biological Chemistry. 284: 30889-96. PMID 19736309 DOI: 10.1074/Jbc.M109.049718  0.717
2009 Rodgers BD, Interlichia JP, Garikipati DK, Mamidi R, Chandra M, Nelson OL, Murry CE, Santana LF. Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling. The Journal of Physiology. 587: 4873-86. PMID 19736304 DOI: 10.1113/Jphysiol.2009.172544  0.661
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