Heather A. Arnett - Publications

Affiliations: 
Amgen Inc., Thousand Oaks, CA, United States 
Area:
Neuroinflammation, multiple sclerosis

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Dietrich D, Martin P, Flacher V, Sun Y, Jarrossay D, Brembilla N, Mueller C, Arnett HA, Palmer G, Towne J, Gabay C. Interleukin-36 potently stimulates human M2 macrophages, Langerhans cells and keratinocytes to produce pro-inflammatory cytokines. Cytokine. 84: 88-98. PMID 27259168 DOI: 10.1016/j.cyto.2016.05.012  0.32
2015 Doody KM, Stanford SM, Sacchetti C, Svensson MND, Coles CH, Mitakidis N, Kiosses WB, Bartok B, Fos C, Cory E, Sah RL, Liu-Bryan R, Boyle DL, Arnett HA, Mustelin T, et al. Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy Science Translational Medicine. 7. DOI: 10.1126/scitranslmed.aaa4616  0.32
2014 Arnett HA, Viney JL. Immune modulation by butyrophilins. Nature Reviews. Immunology. 14: 559-69. PMID 25060581 DOI: 10.1038/nri3715  0.32
2013 Swanson RM, Gavin MA, Escobar SS, Rottman JB, Lipsky BP, Dube S, Li L, Bigler J, Wolfson M, Arnett HA, Viney JL. Butyrophilin-like 2 modulates B7 costimulation to induce Foxp3 expression and regulatory T cell development in mature T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 2027-35. PMID 23359506 DOI: 10.4049/jimmunol.1201760  0.32
2013 Stanford SM, Maestre MF, Campbell AM, Bartok B, Kiosses WB, Boyle DL, Arnett HA, Mustelin T, Firestein GS, Bottini N. Protein tyrosine phosphatase expression profile of rheumatoid arthritis fibroblast-like synoviocytes: a novel role of SH2 domain-containing phosphatase 2 as a modulator of invasion and survival. Arthritis and Rheumatism. 65: 1171-80. PMID 23335101 DOI: 10.1002/art.37872  0.32
2012 Harrington PE, Croghan MD, Fotsch C, Frohn M, Lanman BA, Pennington LD, Pickrell AJ, Reed AB, Sham KK, Tasker A, Arnett HA, Fiorino M, Lee MR, McElvain M, Morrison HG, et al. Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core. Acs Medicinal Chemistry Letters. 3: 74-8. PMID 24900374 DOI: 10.1021/ml200252b  0.32
2012 Pennington LD, Croghan MD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, ... ... Arnett HA, et al. Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activity. Bioorganic & Medicinal Chemistry Letters. 22: 527-31. PMID 22104144 DOI: 10.1016/j.bmcl.2011.10.085  0.32
2011 Cee VJ, Frohn M, Lanman BA, Golden J, Muller K, Neira S, Pickrell A, Arnett H, Buys J, Gore A, Fiorino M, Horner M, Itano A, Lee MR, McElvain M, et al. Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5. Acs Medicinal Chemistry Letters. 2: 107-12. PMID 24900288 DOI: 10.1021/ml100306h  0.32
2011 Pennington LD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Croghan MD, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, ... ... Arnett HA, et al. 4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1. Acs Medicinal Chemistry Letters. 2: 752-7. PMID 24900263 DOI: 10.1021/ml2001399  0.32
2011 Weinger JG, Brosnan CF, Loudig O, Goldberg MF, Macian F, Arnett HA, Prieto AL, Tsiperson V, Shafit-Zagardo B. Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis. Journal of Neuroinflammation. 8: 49. PMID 21569627 DOI: 10.1186/1742-2094-8-49  0.32
2011 Shen M, Siu S, Byrd S, Edelmann KH, Patel N, Ketchem RR, Mehlin C, Arnett HA, Hasegawa H. Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31. Experimental Cell Research. 317: 976-93. PMID 21182835 DOI: 10.1016/j.yexcr.2010.12.012  0.32
2010 Arnett HA, Viney JL. Gatekeepers of intestinal inflammation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 59: 1-14. PMID 20066780 DOI: 10.1007/s00011-009-0091-x  0.32
2009 Chen Y, Wu H, Wang S, Koito H, Li J, Ye F, Hoang J, Escobar SS, Gow A, Arnett HA, Trapp BD, Karandikar NJ, Hsieh J, Lu QR. The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nature Neuroscience. 12: 1398-406. PMID 19838178 DOI: 10.1038/nn.2410  0.32
2009 Arnett HA, Viney JL. Recent developments in IBD and the B7 family of costimulatory molecules. Current Opinion in Investigational Drugs (London, England : 2000). 10: 443-51. PMID 19431077  0.32
2009 Arnett HA, Escobar SS, Viney JL. Regulation of costimulation in the era of butyrophilins. Cytokine. 46: 370-5. PMID 19380239 DOI: 10.1016/j.cyto.2009.03.009  0.32
2008 Mozaffarian A, Brewer AW, Trueblood ES, Luzina IG, Todd NW, Atamas SP, Arnett HA. Mechanisms of oncostatin M-induced pulmonary inflammation and fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 181: 7243-53. PMID 18981146  0.32
2008 Duan H, Fleming J, Pritchard DK, Amon LM, Xue J, Arnett HA, Chen G, Breen P, Buckner JH, Molitor JA, Elkon KB, Schwartz SM. Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma. Arthritis and Rheumatism. 58: 1465-74. PMID 18438864 DOI: 10.1002/art.23451  0.32
2008 Arnett HA, Swanson RM, Viney JL. Cosignaling complexity gets more convoluted: The emerging importance of the B7-like butyrophilin family of immune regulators Current Immunology Reviews. 4: 43-52. DOI: 10.2174/157339508783597307  0.32
2007 Arnett HA, Viney JL. Considerations for the sensible use of rodent models of inflammatory disease in predicting efficacy of new biological therapeutics in the clinic. Advanced Drug Delivery Reviews. 59: 1084-92. PMID 17804112 DOI: 10.1016/j.addr.2007.06.013  0.32
2007 Plant SR, Iocca HA, Wang Y, Thrash JC, O'Connor BP, Arnett HA, Fu YX, Carson MJ, Ting JP. Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7429-37. PMID 17626203 DOI: 10.1523/JNEUROSCI.1307-07.2007  0.32
2007 Arnett HA, Escobar SS, Gonzalez-Suarez E, Budelsky AL, Steffen LA, Boiani N, Zhang M, Siu G, Brewer AW, Viney JL. BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation. Journal of Immunology (Baltimore, Md. : 1950). 178: 1523-33. PMID 17237401  0.32
2006 Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, Anderson DJ, Stiles CD, Rowitch DH. Development of NG2 neural progenitor cells requires Olig gene function. Proceedings of the National Academy of Sciences of the United States of America. 103: 7853-8. PMID 16682644 DOI: 10.1073/pnas.0511001103  0.32
2006 Plant SR, Wang Y, Vasseur S, Thrash JC, McMahon EJ, Bergstralh DT, Arnett HA, Miller SD, Carson MJ, Iovanna JL, Ting JP. Upregulation of the stress-associated gene p8 in mouse models of demyelination and in multiple sclerosis tissues. Glia. 53: 529-37. PMID 16374777 DOI: 10.1002/glia.20297  0.32
2005 Plant SR, Arnett HA, Ting JP. Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination. Glia. 49: 1-14. PMID 15382206 DOI: 10.1002/glia.20089  0.64
2004 Arnett HA, Fancy SP, Alberta JA, Zhao C, Plant SR, Kaing S, Raine CS, Rowitch DH, Franklin RJ, Stiles CD. bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. Science (New York, N.Y.). 306: 2111-5. PMID 15604411 DOI: 10.1126/science.1103709  0.32
2004 Arancibia-Cárcamo CV, Osawa H, Arnett HA, Háskova Z, George AJ, Ono SJ, Ting JP, Streilein JW. A CIITA-independent pathway that promotes expression of endogenous rather than exogenous peptides in immune-privileged sites. European Journal of Immunology. 34: 471-80. PMID 14768052 DOI: 10.1002/eji.200324195  0.32
2003 Arnett HA, Wang Y, Matsushima GK, Suzuki K, Ting JP. Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9824-32. PMID 14586011  0.32
2002 Arnett HA, Hellendall RP, Matsushima GK, Suzuki K, Laubach VE, Sherman P, Ting JP. The protective role of nitric oxide in a neurotoxicant-induced demyelinating model. Journal of Immunology (Baltimore, Md. : 1950). 168: 427-33. PMID 11751989  0.32
2001 Arnett HA, Mason J, Marino M, Suzuki K, Matsushima GK, Ting JP. TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. Nature Neuroscience. 4: 1116-22. PMID 11600888 DOI: 10.1038/nn738  0.32
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