Charles D. Stiles - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
developmental neurobiology
Website:
https://www.dana-farber.org/find-a-doctor/charles-d-stiles/

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Reitman ZJ, Paolella BR, Bergthold G, Pelton K, Becker S, Jones R, Sinai CE, Malkin H, Huang Y, Grimmet L, Herbert ZT, Sun Y, Weatherbee JL, Alberta JA, Daley JF, ... ... Stiles CD, et al. Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells. Nature Communications. 10: 3731. PMID 31427603 DOI: 10.1038/S41467-019-11493-2  0.646
2019 Reitman ZJ, Paolella B, Bergthold G, Pelton K, Jones R, Becker S, Sinai CE, Malkin H, Huang Y, Grimmett L, Herbert ZT, Sun Y, Weatherbee J, Alberta J, Daley J, ... ... Stiles C, et al. Abstract 3647: Single cell RNA sequencing reveals mitogenic and progenitor gene programs inBRAF-rearranged pilocytic astrocytomas Cancer Research. 79: 3647-3647. DOI: 10.1158/1538-7445.Am2019-3647  0.648
2019 Reitman Z, Paolella B, Bergthold G, Pelton K, Becker S, Jones R, Sinai C, Malkin H, Huang Y, Grimmet L, Herbert Z, Sun Y, Weatherbee J, Qian K, Condurat A, ... ... Stiles C, et al. LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS Neuro-Oncology. 21: ii99-ii99. DOI: 10.1093/Neuonc/Noz036.148  0.601
2017 Zhou J, Tien AC, Alberta JA, Ficarro SB, Griveau A, Sun Y, Deshpande JS, Card JD, Morgan-Smith M, Michowski W, Hashizume R, James CD, Ligon KL, Snider WD, Sicinski P, ... ... Stiles CD, et al. A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2. Cell Reports. 18: 3167-3177. PMID 28355568 DOI: 10.1016/J.Celrep.2017.03.003  0.433
2017 Paolella BR, Gibson WJ, Urbanski LM, Alberta JA, Zack TI, Bandopadhayay P, Nichols CA, Agarwalla PK, Brown MS, Lamothe R, Yu Y, Choi PS, Obeng EA, Heckl D, Wei G, ... ... Stiles CD, et al. Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability. Elife. 6. PMID 28177281 DOI: 10.7554/Elife.23268  0.323
2017 Sun Y, Alberta JA, Pilarz C, Calligaris D, Chadwick EJ, Ramkissoon SH, Ramkissoon LA, Garcia VM, Mazzola E, Goumnerova L, Kane M, Yao Z, Kieran MW, Ligon KL, Hahn WC, ... ... Stiles CD, et al. A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas. Neuro-Oncology. PMID 28082416 DOI: 10.1093/Neuonc/Now261  0.606
2017 Bandopadhayay P, Ramkissoon S, Hwang J, Ramkissoon L, Greenwald N, Schumacher S, O’Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi W, Chang M, ... ... Stiles C, et al. GENE-09. PRECISION MEDICINE ANALYSIS OF 203 PEDIATRIC BRAIN TUMORS REVEALS CLINICALLY RELEVANT GENOMIC ALTERATIONS Neuro-Oncology. 19: iv20-iv20. DOI: 10.1093/Neuonc/Nox083.080  0.303
2016 Selt F, Hohloch J, Hielscher T, Sahm F, Capper D, Korshunov A, Usta D, Brabetz S, Ridinger J, Ecker J, Oehme I, Gronych J, Marquardt V, Pauck D, Bächli H, ... Stiles CD, et al. Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing. Oncotarget. PMID 28002790 DOI: 10.18632/oncotarget.14004  0.396
2016 Edwards AL, Meijer DH, Guerra RM, Molenaar RJ, Alberta JA, Bernal F, Bird GH, Stiles CD, Walensky LD. Challenges in Targeting a Basic Helix-Loop-Helix Transcription Factor with Hydrocarbon-Stapled Peptides. Acs Chemical Biology. PMID 27643505 DOI: 10.1021/Acschembio.6B00465  0.749
2016 Ni J, Xie S, Ramkissoon SH, Luu V, Sun Y, Bandopadhayay P, Beroukhim R, Roberts TM, Stiles CD, Segal RA, Ligon KL, Hahn WC, Zhao JJ. Tyrosine receptor kinase B is a drug target in astrocytomas. Neuro-Oncology. PMID 27402815 DOI: 10.1093/Neuonc/Now139  0.597
2016 Paolella BR, Stiles CD. Gliomas "Dope Up" for Growth. Cancer Cell. 29: 778-80. PMID 27300432 DOI: 10.1016/j.ccell.2016.05.010  0.342
2016 Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, ... ... Stiles CD, et al. MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nature Genetics. PMID 26829751 DOI: 10.1038/Ng.3500  0.336
2016 Kieran MW, Sun Y, Pilarz C, Calligaris D, Chadwick EJ, Alberta JA, Ramkissoon SH, Ramkissoon LA, Garcia VM, Wilkinson K, Kane M, Goumnerova L, Chi SN, Manley P, Wright KD, ... ... Stiles CD, et al. LG-47TYPE II RAF INHIBITORS INHIBIT BRAF MUTATIONS AND TRUNCATED FUSIONS IN PEDIATRIC LOW-GRADE GLIOMAS Neuro-Oncology. 18: iii89.2-iii89. DOI: 10.1093/Neuonc/Now075.47  0.591
2015 Chadwick EJ, Yang DP, Filbin MG, Mazzola E, Sun Y, Behar O, Pazyra-Murphy MF, Goumnerova L, Ligon KL, Stiles CD, Segal RA. A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies. Journal of Visualized Experiments : Jove. PMID 26575352 DOI: 10.3791/53304  0.597
2015 Filbin MG, Stiles CD. Of Brains and Blood: Developmental Origins of Glioma Diversity? Cancer Cell. 28: 403-4. PMID 26461085 DOI: 10.1016/j.ccell.2015.09.013  0.331
2015 Bergthold G, Bandopadhayay P, Hoshida Y, Ramkissoon S, Ramkissoon L, Rich B, Maire CL, Paolella BR, Schumacher SE, Tabak B, Ferrer-Luna R, Ozek M, Sav A, Santagata S, Wen PY, ... ... Stiles C, et al. Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype. Neuro-Oncology. PMID 25825052 DOI: 10.1093/Neuonc/Nov045  0.568
2015 Kupp R, Cascio CL, Rauf F, Meijer D, Stiles CD, Sanai N, LaBaer J, Mehta SV. Abstract B20: Targeting Olig2 co-regulators for malignant glioma therapy Brain. 75. DOI: 10.1158/1538-7445.Brain15-B20  0.775
2015 Griveau A, Shelton S, Tien A, Seano G, Yuen T, Sabo J, Lau J, Jahangiri A, Huillard E, Phillips J, Persson A, Oldham M, Weiss W, Aghi M, Stiles C, et al. ANGI-04Olig2 REGULATES Wnt7b EXPRESSION AND VASCULATURE CHARACTERISTICS IN GLIOMA Neuro-Oncology. 17: v41.4-v41. DOI: 10.1093/Neuonc/Nov207.04  0.378
2014 Meijer DH, Sun Y, Liu T, Kane MF, Alberta JA, Adelmant G, Kupp R, Marto JA, Rowitch DH, Nakatani Y, Stiles CD, Mehta S. An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8507-18. PMID 24948806 DOI: 10.1523/Jneurosci.0309-14.2014  0.777
2014 Bergthold G, Bandopadhayay P, Bi WL, Ramkissoon L, Stiles C, Segal RA, Beroukhim R, Ligon KL, Grill J, Kieran MW. Pediatric low-grade gliomas: how modern biology reshapes the clinical field. Biochimica Et Biophysica Acta. 1845: 294-307. PMID 24589977 DOI: 10.1016/J.Bbcan.2014.02.004  0.538
2014 Silbereis JC, Nobuta H, Tsai HH, Heine VM, McKinsey GL, Meijer DH, Howard MA, Petryniak MA, Potter GB, Alberta JA, Baraban SC, Stiles CD, Rubenstein JL, Rowitch DH. Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain. Neuron. 81: 574-87. PMID 24507192 DOI: 10.1016/J.Neuron.2013.11.024  0.747
2014 Calligaris D, Loginov D, Machaidze R, Alberta JA, Stiles CD, Love JC, Agar NYR. Ni-10A Mass Spectrometry Imaging Platform To Study Drug-Susceptibility Of Brain Tumors Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou264.10  0.324
2013 Pak E, Segal RA, Stiles CD. New progenitors NESTIN(g) in the EGL. Nature Neuroscience. 16: 1710-2. PMID 24270268 DOI: 10.1038/Nn.3580  0.54
2013 Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD, Van Hummelen P, MacConaill LE, Pouissant-Young T, ... ... Stiles CD, et al. Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. Proceedings of the National Academy of Sciences of the United States of America. 110: 8188-93. PMID 23633565 DOI: 10.1073/Pnas.1300252110  0.349
2012 Meijer DH, Kane MF, Mehta S, Liu H, Harrington E, Taylor CM, Stiles CD, Rowitch DH. Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2. Nature Reviews. Neuroscience. 13: 819-31. PMID 23165259 DOI: 10.1038/Nrn3386  0.767
2012 Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, ... ... Stiles CD, et al. Identification of molecular compartments and genetic circuitry in the developing mammalian kidney. Development (Cambridge, England). 139: 1863-73. PMID 22510988 DOI: 10.1242/Dev.074005  0.397
2011 Tian Y, Rich BE, Vena N, Craig JM, Macconaill LE, Rajaram V, Goldman S, Taha H, Mahmoud M, Ozek M, Sav A, Longtine JA, Lindeman NI, Garraway LA, Ligon AH, ... Stiles CD, et al. Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. The Journal of Molecular Diagnostics : Jmd. 13: 669-77. PMID 21884820 DOI: 10.1016/J.Jmoldx.2011.07.002  0.314
2011 Mehta S, Huillard E, Kesari S, Maire CL, Golebiowski D, Harrington EP, Alberta JA, Kane MF, Theisen M, Ligon KL, Rowitch DH, Stiles CD. The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. Cancer Cell. 19: 359-71. PMID 21397859 DOI: 10.1016/J.Ccr.2011.01.035  0.314
2011 Sun Y, Meijer DH, Alberta JA, Mehta S, Kane MF, Tien AC, Fu H, Petryniak MA, Potter GB, Liu Z, Powers JF, Runquist IS, Rowitch DH, Stiles CD. Phosphorylation state of Olig2 regulates proliferation of neural progenitors. Neuron. 69: 906-17. PMID 21382551 DOI: 10.1016/J.Neuron.2011.02.005  0.788
2010 Qin Y, Yao L, King EE, Buddavarapu K, Lenci RE, Chocron ES, Lechleiter JD, Sass M, Aronin N, Schiavi F, Boaretto F, Opocher G, Toledo RA, Toledo SPA, Stiles C, et al. Germline mutations in TMEM127 confer susceptibility to pheochromocytoma Nature Genetics. 42: 229-233. PMID 20154675 DOI: 10.1038/Ng.533  0.326
2009 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD. A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11399-408. PMID 19741146 DOI: 10.1523/Jneurosci.0160-09.2009  0.377
2009 Sauvageot CM, Weatherbee JL, Kesari S, Winters SE, Barnes J, Dellagatta J, Ramakrishna NR, Stiles CD, Kung AL, Kieran MW, Wen PY. Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells. Neuro-Oncology. 11: 109-21. PMID 18682579 DOI: 10.1215/15228517-2008-060  0.37
2008 Stiles CD, Rowitch DH. Glioma stem cells: a midterm exam. Neuron. 58: 832-46. PMID 18579075 DOI: 10.1016/j.neuron.2008.05.031  0.311
2007 Sauvageot CM, Kesari S, Stiles CD. Molecular pathogenesis of adult brain tumors and the role of stem cells. Neurologic Clinics. 25: 891-924, vii. PMID 17964020 DOI: 10.1016/J.Ncl.2007.07.014  0.344
2007 Kesari S, Jackson-Grusby L, Stiles CD. "Smad"eningly erratic: target gene methylation determines whether TGFbeta promotes or suppresses malignant glioma. Developmental Cell. 12: 324-5. PMID 17336898 DOI: 10.1016/J.Devcel.2007.02.008  0.325
2007 Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron. 53: 503-17. PMID 17296553 DOI: 10.1016/J.Neuron.2007.01.009  0.393
2006 Kesari S, Stiles CD. The bad seed: PDGF receptors link adult neural progenitors to glioma stem cells. Neuron. 51: 151-3. PMID 16846849 DOI: 10.1016/J.Neuron.2006.07.001  0.35
2006 Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, Anderson DJ, Stiles CD, Rowitch DH. Development of NG2 neural progenitor cells requires Olig gene function. Proceedings of the National Academy of Sciences of the United States of America. 103: 7853-8. PMID 16682644 DOI: 10.1073/Pnas.0511001103  0.736
2006 Sun T, Hafler BP, Kaing S, Kitada M, Ligon KL, Widlund HR, Yuk DI, Stiles CD, Rowitch DH. Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. Developmental Biology. 292: 152-64. PMID 16469306 DOI: 10.1016/J.Ydbio.2005.12.047  0.328
2006 Kesari S, Ramakrishna N, Sauvageot C, Stiles CD, Wen PY. Targeted molecular therapy of malignant gliomas. Current Oncology Reports. 8: 58-70. PMID 16464405 DOI: 10.1007/S11912-006-0011-Y  0.356
2005 Dahia PL, Ross KN, Wright ME, Hayashida CY, Santagata S, Barontini M, Kung AL, Sanso G, Powers JF, Tischler AS, Hodin R, Heitritter S, Moore F, Dluhy R, Sosa JA, ... ... Stiles CD, et al. A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas. Plos Genetics. 1: 72-80. PMID 16103922 DOI: 10.1371/Journal.Pgen.0010008  0.325
2005 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. Bmc Developmental Biology. 5: 14. PMID 16033648 DOI: 10.1186/1471-213X-5-14  0.352
2005 Kesari S, Ramakrishna N, Sauvageot C, Stiles CD, Wen PY. Targeted molecular therapy of malignant gliomas. Current Neurology and Neuroscience Reports. 5: 186-97. PMID 15865884 DOI: 10.1007/S11910-005-0046-8  0.356
2005 Sauvageot C, Dahia PL, Lipan O, Park JK, Chang MS, Alberta JA, Stiles CD. Distinct temporal genetic signatures of neurogenic and gliogenic cues in cortical stem cell cultures. Journal of Neurobiology. 62: 121-33. PMID 15389679 DOI: 10.1002/neu.20072  0.421
2004 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, ... ... Stiles CD, et al. Mouse brain organization revealed through direct genome-scale TF expression analysis. Science (New York, N.Y.). 306: 2255-7. PMID 15618518 DOI: 10.1126/Science.1104935  0.341
2004 Arnett HA, Fancy SP, Alberta JA, Zhao C, Plant SR, Kaing S, Raine CS, Rowitch DH, Franklin RJ, Stiles CD. bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. Science (New York, N.Y.). 306: 2111-5. PMID 15604411 DOI: 10.1126/Science.1103709  0.707
2004 Ligon KL, Alberta JA, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. Journal of Neuropathology and Experimental Neurology. 63: 499-509. PMID 15198128 DOI: 10.1093/Jnen/63.5.499  0.348
2003 Bithell A, Alberta J, Hornby F, Stiles CD, Williams BP. Expression of the guanine nucleotide exchange factor, mr-gef, is regulated during the differentiation of specific subsets of telencephalic neurons. Brain Research. Developmental Brain Research. 146: 107-18. PMID 14643017 DOI: 10.1016/j.devbrainres.2003.09.017  0.378
2003 Sun T, Dong H, Wu L, Kane M, Rowitch DH, Stiles CD. Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9547-56. PMID 14573534 DOI: 10.1523/Jneurosci.23-29-09547.2003  0.325
2003 Ross SE, Greenberg ME, Stiles CD. Basic helix-loop-helix factors in cortical development. Neuron. 39: 13-25. PMID 12848929 DOI: 10.1016/S0896-6273(03)00365-9  0.357
2002 Bhattacharyya A, Watson FL, Pomeroy SL, Zhang YZ, Stiles CD, Segal RA. High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors. Journal of Neurobiology. 51: 302-12. PMID 12150505 DOI: 10.1002/Neu.10062  0.536
2002 Sauvageot CM, Stiles CD. Molecular mechanisms controlling cortical gliogenesis. Current Opinion in Neurobiology. 12: 244-9. PMID 12049929 DOI: 10.1016/S0959-4388(02)00322-7  0.394
2002 Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, Rowitch DH. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell. 109: 75-86. PMID 11955448 DOI: 10.1016/S0092-8674(02)00678-5  0.35
2001 Alberta JA, Park SK, Mora J, Yuk D, Pawlitzky I, Iannarelli P, Vartanian T, Stiles CD, Rowitch DH. Sonic hedgehog is required during an early phase of oligodendrocyte development in mammalian brain. Molecular and Cellular Neurosciences. 18: 434-41. PMID 11640898 DOI: 10.1006/mcne.2001.1026  0.339
2001 Lu QR, Cai L, Rowitch D, Cepko CL, Stiles CD. Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex. Nature Neuroscience. 4: 973-4. PMID 11574831 DOI: 10.1038/nn718  0.329
2001 Sun T, Echelard Y, Lu R, Yuk DI, Kaing S, Stiles CD, Rowitch DH. Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube. Current Biology : Cb. 11: 1413-20. PMID 11566099 DOI: 10.1016/S0960-9822(01)00441-9  0.32
2001 Lu QR, Park JK, Noll E, Chan JA, Alberta J, Yuk D, Alzamora MG, Louis DN, Stiles CD, Rowitch DH, Black PM. Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 10851-6. PMID 11526205 DOI: 10.1073/Pnas.181340798  0.428
2001 Kim HA, Ratner N, Roberts TM, Stiles CD. Schwann cell proliferative responses to cAMP and Nf1 are mediated by cyclin D1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1110-6. PMID 11160381 DOI: 10.1523/Jneurosci.21-04-01110.2001  0.419
2000 Wang WL, Healy ME, Sattler M, Verma S, Lin J, Maulik G, Stiles CD, Griffin JD, Johnson BE, Salgia R. Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571. Oncogene. 19: 3521-8. PMID 10918610 DOI: 10.1038/Sj.Onc.1203698  0.366
2000 Kim HA, Pomeroy SL, Whoriskey W, Pawlitzky I, Benowitz LI, Sicinski P, Stiles CD, Roberts TM. A developmentally regulated switch directs regenerative growth of Schwann cells through cyclin D1. Neuron. 26: 405-16. PMID 10839359 DOI: 10.1016/S0896-6273(00)81173-3  0.318
2000 Lu QR, Yuk D, Alberta JA, Zhu Z, Pawlitzky I, Chan J, McMahon AP, Stiles CD, Rowitch DH. Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron. 25: 317-29. PMID 10719888 DOI: 10.1016/S0896-6273(00)80897-1  0.412
1999 Park JK, Williams BP, Alberta JA, Stiles CD. Bipotent cortical progenitor cells process conflicting cues for neurons and glia in a hierarchical manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10383-9. PMID 10575035 DOI: 10.1523/Jneurosci.19-23-10383.1999  0.358
1999 Alberta JA, Auger KR, Batt D, Iannarelli P, Hwang G, Elliott HL, Duke R, Roberts TM, Stiles CD. Platelet-derived growth factor stimulation of monocyte chemoattractant protein-1 gene expression is mediated by transient activation of the phosphoinositide 3-kinase signal transduction pathway. The Journal of Biological Chemistry. 274: 31062-7. PMID 10521506 DOI: 10.1074/Jbc.274.43.31062  0.406
1999 Watson FL, Porcionatto MA, Bhattacharyya A, Stiles CD, Segal RA. TrkA glycosylation regulates receptor localization and activity. Journal of Neurobiology. 39: 323-36. PMID 10235685 DOI: 10.1002/(Sici)1097-4695(199905)39:2<323::Aid-Neu15>3.0.Co;2-4  0.577
1999 Kim JY, Sutton ME, Lu DJ, Cho TA, Goumnerova LC, Goritchenko L, Kaufman JR, Lam KK, Billet AL, Tarbell NJ, Wu J, Allen JC, Stiles CD, Segal RA, Pomeroy SL. Activation of neurotrophin-3 receptor TrkC induces apoptosis in medulloblastomas. Cancer Research. 59: 711-9. PMID 9973222  0.563
1999 Dahia PLM, Aguiar RCT, Alberta J, Kum JB, Caron S, Sill H, Marsh DJ, Ritz J, Freedman A, Stiles C, Eng C. PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies Human Molecular Genetics. 8: 185-193. PMID 9931326 DOI: 10.1093/Hmg/8.2.185  0.383
1997 Alberta JA, Stiles CD. Phosphorylation-directed antibodies in high-flux screens for compounds that modulate signal transduction. Biotechniques. 23: 490-3. PMID 9298221 DOI: 10.2144/97233St07  0.311
1997 Bhattacharyya A, Watson FL, Bradlee TA, Pomeroy SL, Stiles CD, Segal RA. Trk receptors function as rapid retrograde signal carriers in the adult nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7007-16. PMID 9278536 DOI: 10.1523/Jneurosci.17-18-07007.1997  0.552
1997 Williams BP, Park JK, Alberta JA, Muhlebach SG, Hwang GY, Roberts TM, Stiles CD. A PDGF-regulated immediate early gene response initiates neuronal differentiation in ventricular zone progenitor cells. Neuron. 18: 553-62. PMID 9136765 DOI: 10.1016/S0896-6273(00)80297-4  0.351
1996 Segal RA, Bhattacharyya A, Rua LA, Alberta JA, Stephens RM, Kaplan DR, Stiles CD. Differential utilization of Trk autophosphorylation sites. The Journal of Biological Chemistry. 271: 20175-81. PMID 8702742 DOI: 10.1074/Jbc.271.33.20175  0.58
1996 Freter RR, Alberta JA, Hwang GY, Wrentmore AL, Stiles CD. Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-kappaB and a 90-kDa phosphoprotein coactivator. The Journal of Biological Chemistry. 271: 17417-24. PMID 8663287 DOI: 10.1074/jbc.271.29.17417  0.334
1995 Shamah SM, Stiles CD. Transdominant negative mutations. Methods in Enzymology. 254: 565-76. PMID 8531715 DOI: 10.1016/0076-6879(95)54040-7  0.377
1995 Guha A, Dashner K, Black PM, Wagner JA, Stiles CD. Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. International Journal of Cancer. Journal International Du Cancer. 60: 168-73. PMID 7829210 DOI: 10.1002/Ijc.2910600206  0.371
1995 Freter RR, Alberta JA, Lam KK, Stiles CD. A new platelet-derived growth factor-regulated genomic element which binds a serine/threonine phosphoprotein mediates induction of the slow immediate-early gene MCP-1. Molecular and Cellular Biology. 15: 315-25. PMID 7799939 DOI: 10.1128/Mcb.15.1.315  0.376
1995 Segal RA, Pomeroy SL, Stiles CD. Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4970-81. PMID 7623126 DOI: 10.1523/Jneurosci.15-07-04970.1995  0.598
1995 Guha A, Glowacka D, Carroll R, Dashner K, Black PM, Stiles CD. Expression of platelet derived growth factor and platelet derived growth factor receptor mRNA in a glioblastoma from a patient with Li-Fraumeni syndrome. Journal of Neurology, Neurosurgery, and Psychiatry. 58: 711-4. PMID 7608673 DOI: 10.1136/Jnnp.58.6.711  0.37
1994 Wang C, Stiles CD. Platelet-derived growth factor alpha receptor gene expression: isolation and characterization of the promoter and upstream regulatory elements. Proceedings of the National Academy of Sciences of the United States of America. 91: 7061-5. PMID 8041746 DOI: 10.1073/pnas.91.15.7061  0.398
1994 Segal RA, Goumnerova LC, Kwon YK, Stiles CD, Pomeroy SL. Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proceedings of the National Academy of Sciences of the United States of America. 91: 12867-71. PMID 7809137 DOI: 10.1073/Pnas.91.26.12867  0.572
1993 Jones SD, Ho L, Smith JC, Yordan C, Stiles CD, Mercola M. The Xenopus platelet-derived growth factor alpha receptor: cDNA cloning and demonstration that mesoderm induction establishes the lineage-specific pattern of ligand and receptor gene expression. Developmental Genetics. 14: 185-93. PMID 8358864 DOI: 10.1002/Dvg.1020140305  0.601
1993 Shamah SM, Stiles CD, Guha A. Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells. Molecular and Cellular Biology. 13: 7203-12. PMID 8246942 DOI: 10.1128/mcb.13.12.7203-7212.1993  0.39
1992 Freter RR, Irminger JC, Porter JA, Jones SD, Stiles CD. A novel 7-nucleotide motif located in 3' untranslated sequences of the immediate-early gene set mediates platelet-derived growth factor induction of the JE gene. Molecular and Cellular Biology. 12: 5288-300. PMID 1448065 DOI: 10.1128/Mcb.12.12.5288  0.386
1992 Epstein RJ, Druker BJ, Roberts TM, Stiles CD. Synthetic phosphopeptide immunogens yield activation-specific antibodies to the c-erbB-2 receptor. Proceedings of the National Academy of Sciences of the United States of America. 89: 10435-9. PMID 1359539 DOI: 10.1073/Pnas.89.21.10435  0.314
1992 Wang C, Shamah SM, Stiles CD. Recombinant PDGF from lower vertebrates: receptor binding and immunochemical analysis with metabolically labeled growth factor. Growth Factors (Chur, Switzerland). 7: 279-88. PMID 1306683 DOI: 10.3109/08977199209046410  0.358
1992 Palmieri SL, Payne J, Stiles CD, Biggers JD, Mercola M. Expression of mouse PDGF-A and PDGF alpha-receptor genes during pre- and post-implantation development: evidence for a developmental shift from an autocrine to a paracrine mode of action. Mechanisms of Development. 39: 181-91. PMID 1292572 DOI: 10.1016/0925-4773(92)90045-L  0.581
1991 Yaeger PC, Stiles CD, Rollins BJ. Human keratinocyte growth-promoting activity on the surface of fibroblasts. Journal of Cellular Physiology. 149: 110-6. PMID 1939339 DOI: 10.1002/jcp.1041490114  0.351
1991 Stephenson DA, Mercola M, Anderson E, Wang CY, Stiles CD, Bowen-Pope DF, Chapman VM. Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation. Proceedings of the National Academy of Sciences of the United States of America. 88: 6-10. PMID 1846043 DOI: 10.1073/Pnas.88.1.6  0.571
1990 Mercola M, Deininger PL, Shamah SM, Porter J, Wang CY, Stiles CD. Dominant-negative mutants of a platelet-derived growth factor gene. Genes & Development. 4: 2333-41. PMID 2279701 DOI: 10.1101/Gad.4.12B.2333  0.625
1990 Wang C, Kelly J, Bowen-Pope DF, Stiles CD. Retinoic acid promotes transcription of the platelet-derived growth factor alpha-receptor gene. Molecular and Cellular Biology. 10: 6781-4. PMID 2174116 DOI: 10.1128/MCB.10.12.6781  0.357
1990 Mercola M, Wang CY, Kelly J, Brownlee C, Jackson-Grusby L, Stiles C, Bowen-Pope D. Selective expression of PDGF A and its receptor during early mouse embryogenesis. Developmental Biology. 138: 114-22. PMID 2155144 DOI: 10.1016/0012-1606(90)90181-H  0.597
1989 Rollins BJ, Stiles CD. Serum-inducible genes. Advances in Cancer Research. 53: 1-32. PMID 2678945 DOI: 10.1016/S0065-230X(08)60277-8  0.409
1989 Hall DJ, Alberta JA, Stiles CD. Labile repressors are involved in the transcriptional control of PDGF-responsive genes. Oncogene Research. 4: 177-84. PMID 2544848  0.499
1989 Hall DJ, Jones SD, Kaplan DR, Whitman M, Rollins BJ, Stiles CD. Evidence for a novel signal transduction pathway activated by platelet-derived growth factor and by double-stranded RNA. Molecular and Cellular Biology. 9: 1705-13. PMID 2542776 DOI: 10.1128/MCB.9.4.1705  0.535
1989 Garcia-Blanco MA, Lengyel P, Morrison E, Brownlee C, Stiles CD, Rutherford M, Hannigan G, Williams BR. Regulation of 2',5'-oligoadenylate synthetase gene expression by interferons and platelet-derived growth factor. Molecular and Cellular Biology. 9: 1060-8. PMID 2542764 DOI: 10.1128/Mcb.9.3.1060  0.407
1989 Hall DJ, Brownlee C, Stiles CD. Interleukin-1 is a potent regulator of JE and KC gene expression in quiescent BALB/c fibroblasts. Journal of Cellular Physiology. 141: 154-9. PMID 2506194 DOI: 10.1002/jcp.1041410123  0.547
1988 Mercola M, Melton DA, Stiles CD. Platelet-derived growth factor A chain is maternally encoded in Xenopus embryos. Science (New York, N.Y.). 241: 1223-5. PMID 3413486 DOI: 10.1126/Science.3413486  0.593
1988 Rollins BJ, Morrison ED, Stiles CD. Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proceedings of the National Academy of Sciences of the United States of America. 85: 3738-42. PMID 3287374 DOI: 10.1073/Pnas.85.11.3738  0.392
1988 Burd PR, Rollins BJ, Wilson SD, Billings PR, Stiles CD, Dorf ME. Comparison of fibroblast and T-cell activation genes. Cellular Immunology. 115: 481-3. PMID 3261640 DOI: 10.1016/0008-8749(88)90200-6  0.324
1988 Jones SD, Hall DJ, Rollins BJ, Stiles CD. Platelet-derived growth factor generates at least two distinct intracellular signals that modulate gene expression. Cold Spring Harbor Symposia On Quantitative Biology. 53: 531-6. PMID 3254779 DOI: 10.1101/Sqb.1988.053.01.061  0.486
1988 Rollins BJ, Stiles CD. Regulation of c-myc and c-fos proto-oncogene expression by animal cell growth factors. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 24: 81-4. PMID 3125143 DOI: 10.1007/Bf02623883  0.392
1987 Rollins BJ, Morrison ED, Stiles CD. A cell-cycle constraint on the regulation of gene expression by platelet-derived growth factor. Science (New York, N.Y.). 238: 1269-71. PMID 3685976 DOI: 10.1126/Science.3685976  0.429
1987 Hall DJ, Stiles CD. Platelet-derived growth factor-inducible genes respond differentially to at least two distinct intracellular second messengers. The Journal of Biological Chemistry. 262: 15302-8. PMID 3117798  0.47
1987 Zullo J, Stiles CD, Garcea RL. Regulation of c-myc and c-fos mRNA levels by polyomavirus: distinct roles for the capsid protein VP1 and the viral early proteins. Proceedings of the National Academy of Sciences of the United States of America. 84: 1210-4. PMID 3029770 DOI: 10.1073/Pnas.84.5.1210  0.366
1987 Cochran BH, Zumstein P, Zullo J, Rollins B, Mercola M, Stiles CD. Differential colony hybridization: molecular cloning from a zero data base. Methods in Enzymology. 147: 64-85. PMID 2444861 DOI: 10.1016/0076-6879(87)47099-7  0.737
1986 Gibson CW, Rittling SR, Hirschhorn RR, Kaczmarek L, Calabretta B, Stiles CD, Baserga R. Cell cycle dependent genes inducible by different mitogens in cells from different species. Molecular and Cellular Biochemistry. 71: 61-9. PMID 3755218 DOI: 10.1007/Bf00219329  0.413
1985 Callahan M, Cochran BH, Stiles CD. The PDGF-inducible 'competence genes': intracellular mediators of the mitogenic response. Ciba Foundation Symposium. 116: 87-97. PMID 4075904 DOI: 10.1002/9780470720974.ch6  0.663
1985 Zullo JN, Cochran BH, Huang AS, Stiles CD. Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells. Cell. 43: 793-800. PMID 3000615 DOI: 10.1016/0092-8674(85)90252-1  0.699
1985 Stiles CD. The biological role of oncogenes--insights from platelet-derived growth factor: Rhoads Memorial Award lecture. Cancer Research. 45: 5215-8. PMID 2996757  0.302
1984 Bockus BJ, Stiles CD. Regulation of cytoskeletal architecture by platelet-derived growth factor, insulin and epidermal growth factor. Experimental Cell Research. 153: 186-97. PMID 6376151 DOI: 10.1016/0014-4827(84)90460-9  0.341
1984 Hendrickson SL, Cochran BH, Reffel AC, Stiles CD. Regulation of gene expression by serum and serum growth factors. Symposium On Fundamental Cancer Research. 37: 71-85. PMID 6335592  0.651
1984 Kelly K, Cochran B, Stiles C, Leder P. The regulation of c-myc by growth signals. Current Topics in Microbiology and Immunology. 113: 117-26. PMID 6332711 DOI: 10.1007/978-3-642-69860-6_22  0.695
1984 Cochran BH, Zullo J, Verma IM, Stiles CD. Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor. Science (New York, N.Y.). 226: 1080-2. PMID 6093261 DOI: 10.1126/Science.6093261  0.693
1984 Armelin HA, Armelin MC, Kelly K, Stewart T, Leder P, Cochran BH, Stiles CD. Functional role for c-myc in mitogenic response to platelet-derived growth factor. Nature. 310: 655-60. PMID 6088986 DOI: 10.1038/310655A0  0.7
1984 Cochran BH, Kelly K, Leder P, Stiles CD. Molecular action of platelet-derived growth factor: Insights to oncogene function Federation Proceedings. 43: no. 3265.  0.639
1983 Cochran BH, Reffel AC, Stiles CD. Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell. 33: 939-47. PMID 6872001 DOI: 10.1016/0092-8674(83)90037-5  0.699
1983 Singh JP, Chaikin MA, Pledger WJ, Scher CD, Stiles CD. Persistence of the mitogenic response to platelet-derived growth factor (competence) does not reflect a long-term interaction between the growth factor and the target cell. The Journal of Cell Biology. 96: 1497-502. PMID 6841457 DOI: 10.1083/Jcb.96.5.1497  0.364
1983 Kelly K, Cochran BH, Stiles CD, Leder P. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell. 35: 603-10. PMID 6606489 DOI: 10.1016/0092-8674(83)90092-2  0.699
1983 Stiles CD. The molecular biology of platelet-derived growth factor. Cell. 33: 653-5. PMID 6307524 DOI: 10.1016/0092-8674(83)90008-9  0.46
1982 Singh JP, Chaikin MA, Stiles CD. Phylogenetic analysis of platelet-derived growth factor by radio-receptor assay. The Journal of Cell Biology. 95: 667-71. PMID 7142300 DOI: 10.1083/Jcb.95.2.667  0.319
1982 Smith JC, Singh JP, Lillquist JS, Goon DS, Stiles CD. Growth factors adherent to cell substrate are mitogenically active in situ. Nature. 296: 154-6. PMID 6278315 DOI: 10.1038/296154A0  0.361
1981 Cochran BH, Lillquist JS, Stiles CD. Post-transcriptional control of protein synthesis in Balb/c-3T3 cells by platelet-derived growth factor and platelet-poor plasma. Journal of Cellular Physiology. 109: 429-38. PMID 6798044 DOI: 10.1002/Jcp.1041090308  0.683
1981 Smith JC, Stiles CD. Cytoplasmic transfer of the mitogenic response to platelet-derived growth factor. Proceedings of the National Academy of Sciences of the United States of America. 78: 4363-7. PMID 6170063 DOI: 10.1073/Pnas.78.7.4363  0.384
1980 Stiles CD, Pledger WJ, Tucker RW, Martin RG, Scher CD. Regulation of the Balb/c-3T3 cell cycle-effects of growth factors. Journal of Supramolecular Structure. 13: 489-99. PMID 6453256 DOI: 10.1002/Jss.400130408  0.356
1980 Frantz CN, Stiles CD, Pledger WJ, Scher CD. Effect of ouabain on growth regulation by serum components in Balb/c-3T3 cells: inhibition of entry into S phase by decreased protein synthesis. Journal of Cellular Physiology. 105: 439-48. PMID 6257737 DOI: 10.1002/Jcp.1041050308  0.322
1979 Scher CD, Stone ME, Stiles CD. Platelet-derived growth factor prevents G0 growth arrest. Nature. 281: 390-2. PMID 481605 DOI: 10.1038/281390a0  0.322
1979 Kaplan DR, Chao FC, Stiles CD, Antoniades HN, Scher CD. Platelet alpha granules contain a growth factor for fibroblasts. Blood. 53: 1043-52. PMID 444648 DOI: 10.1182/Blood.V53.6.1043.Bloodjournal5361043  0.33
1979 Scher CD, Shepard RC, Antoniades HN, Stiles CD. Platelet-derived growth factor and the regulation of the mammalian fibroblast cell cycle. Biochimica Et Biophysica Acta. 560: 217-41. PMID 380651 DOI: 10.1016/0304-419X(79)90020-9  0.388
1979 Frantz CN, Stiles CD, Scher CD. The tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate enhances the proliferative response of Balb/c-3T3 cells to hormonal growth factors. Journal of Cellular Physiology. 100: 413-24. PMID 314942 DOI: 10.1002/jcp.1041000305  0.377
1979 Stiles CD, Capone GT, Scher CD, Antoniades HN, Van Wyk JJ, Pledger WJ. Dual control of cell growth by somatomedins and platelet-derived growth factor. Proceedings of the National Academy of Sciences of the United States of America. 76: 1279-83. PMID 312500 DOI: 10.1073/Pnas.76.3.1279  0.393
1979 Antoniades HN, Scher CD, Stiles CD. Purification of human platelet-derived growth factor. Proceedings of the National Academy of Sciences of the United States of America. 76: 1809-13. PMID 287022 DOI: 10.1073/Pnas.76.4.1809  0.349
1979 Tucker RW, Scher CD, Stiles CD. Centriole deciliation associated with the early response of 3T3 cells to growth factors but not to SV40. Cell. 18: 1065-72. PMID 229969 DOI: 10.1016/0092-8674(79)90219-8  0.375
1979 Stiles CD, Isberg RR, Pledger WJ, Antoniades HN, Scher CD. Control of the Balb/c-3T3 cell cycle by nutrients and serum factors: analysis using platelet-derived growth factor and platelet-poor plasma. Journal of Cellular Physiology. 99: 395-405. PMID 222785 DOI: 10.1002/Jcp.1040990314  0.37
1978 Pledger WJ, Stiles CD, Antoniades HN, Scher CD. An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis. Proceedings of the National Academy of Sciences of the United States of America. 75: 2839-43. PMID 275855 DOI: 10.1073/Pnas.75.6.2839  0.301
1978 Scher CD, Pledger WJ, Martin P, Antoniades H, Stiles CD. Transforming viruses directly reduce the cellular growth requirement for a platelet derived growth factor. Journal of Cellular Physiology. 97: 371-80. PMID 215597 DOI: 10.1002/Jcp.1040970312  0.388
1977 Pledger WJ, Stiles CD, Antoniades HN, Scher CD. Induction of DNA synthesis in BALB/c 3T3 cells by serum components: reevaluation of the commitment process. Proceedings of the National Academy of Sciences of the United States of America. 74: 4481-5. PMID 270695 DOI: 10.1073/Pnas.74.10.4481  0.332
1976 Stiles CD, Desmond W, Chuman LM, Sato G, Saier MH. Growth control of heterologous tissue culture cells in the congenitally athymic nude mouse. Cancer Research. 36: 1353-60. PMID 1260760  0.6
1976 Stiles CD, Desmond W, Chuman LM, Sato G, Saier MH. Relationship of cell growth behavior in vitro to tumorigenicity in athymic nude mice. Cancer Research. 36: 3300-5. PMID 975091  0.602
1976 Stiles CD, Roberts PE, Saier MH, Sato G. Growth regulation and suppression of metastasis in the congenitally athymic nude mouse. Hã¤Matologie Und Bluttransfusion. 19: 185-94. PMID 188726  0.591
1976 Stiles CD, Lee KL, Kenney FT. Differential degradation of messenger RNAs in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 73: 2634-8. PMID 8777 DOI: 10.1073/Pnas.73.8.2634  0.631
1975 Stiles CD, Desmond W, Sato G, Saier MH. Failure of human cells transformed by simian virus 40 to form tumors in athymic nude mice. Proceedings of the National Academy of Sciences of the United States of America. 72: 4971-5. PMID 174085 DOI: 10.1073/Pnas.72.12.4971  0.618
1973 Kenney FT, Lee KL, Stiles CD, Fritz JE. Further evidence against post-transcriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells. Nature: New Biology. 246: 208-10. PMID 4148697 DOI: 10.1038/Newbio246208A0  0.676
1972 Kenney FT, Lee KL, Stiles CD. Degradation of messenger RNA in mammalian cells. Acta Endocrinologica. Supplementum. 168: 369-80. PMID 4404131 DOI: 10.1530/Acta.0.071S369  0.618
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