Barbara E. Ehrlich - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Intracellular Signaling
Website:
http://info.med.yale.edu/pharm/hermen/

148 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kuo IY, Brill AL, Lemos FO, Jiang JY, Falcone JL, Kimmerling EP, Cai Y, Dong K, Kaplan DL, Wallace DP, Hofer AM, Ehrlich BE. Polycystin 2 regulates mitochondrial Ca signaling, bioenergetics, and dynamics through mitofusin 2. Science Signaling. 12. PMID 31064883 DOI: 10.1126/scisignal.aat7397  0.88
2019 Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, ... Ehrlich BE, et al. TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells. Nature Communications. 10: 2024. PMID 31048699 DOI: 10.1038/s41467-019-10045-y  0.88
2018 Boeckel GR, Ehrlich BE. NCS-1 is a regulator of calcium signaling in health and disease. Biochimica Et Biophysica Acta. PMID 29746899 DOI: 10.1016/j.bbamcr.2018.05.005  0.44
2017 Ruan HB, Ma Y, Torres S, Zhang B, Feriod C, Heck RM, Qian K, Fu M, Li X, Nathanson MH, Bennett AM, Nie Y, Ehrlich BE, Yang X. Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation. Genes & Development. PMID 28903979 DOI: 10.1101/gad.305441.117  0.44
2017 Giehl E, Lemos FO, Huang Y, Giordano FJ, Kuo IY, Ehrlich BE. Polycystin 2-dependent cardio-protective mechanisms revealed by cardiac stress. Pflugers Archiv : European Journal of Physiology. PMID 28762163 DOI: 10.1007/s00424-017-2042-7  0.88
2017 Lemos FO, Ehrlich BE. Polycystin and calcium signaling in cell death and survival. Cell Calcium. PMID 28601384 DOI: 10.1016/j.ceca.2017.05.011  0.88
2016 Yi JS, Huang Y, Kwaczala AT, Kuo IY, Ehrlich BE, Campbell SG, Giordano FJ, Bennett AM. Low-dose dasatinib rescues cardiac function in Noonan syndrome. Jci Insight. 1: e90220. PMID 27942593 DOI: 10.1172/jci.insight.90220  0.88
2016 Padovano V, Kuo IY, Stavola LK, Aerni HR, Flaherty BJ, Chapin HC, Ma M, Somlo S, Boletta A, Ehrlich BE, Rinehart J, Caplan MJ. The polycystins are modulated by cellular oxygen sensing pathways and regulate mitochondrial function. Molecular Biology of the Cell. PMID 27881662 DOI: 10.1091/mbc.E16-08-0597  0.88
2016 Wang B, Boeckel GR, Huynh L, Nguyen L, Cao W, De La Cruz EM, Kaftan EJ, Ehrlich BE. Neuronal Calcium Sensor 1 Has Two Variants with Distinct Calcium Binding Characteristics. Plos One. 11: e0161414. PMID 27575489 DOI: 10.1371/journal.pone.0161414  0.88
2016 Kuo IY, Duong SL, Nguyen L, Ehrlich BE. Decreased Polycystin 2 Levels Result in Non-Renal Cardiac Dysfunction with Aging. Plos One. 11: e0153632. PMID 27081851 DOI: 10.1371/journal.pone.0153632  0.88
2015 Yang Y, Hodsdon ME, Lolis EJ, Ehrlich BE. Conformational dynamics of Ca2+-dependent responses in the polycystin-2 C-terminal tail. The Biochemical Journal. PMID 26574436 DOI: 10.1042/BJ20151031  1
2015 DesRochers TM, Kuo IY, Kimmerling EP, Ehrlich BE, Kaplan DL. The effects of mycoplasma contamination upon the ability to form bioengineered 3D kidney cysts. Plos One. 10: e0120097. PMID 25793639 DOI: 10.1371/journal.pone.0120097  1
2015 Yang Y, Keeler C, Kuo IY, Lolis EJ, Ehrlich BE, Hodsdon ME. Oligomerization of the polycystin-2 C-terminal tail and effects on its Ca2+-binding properties. The Journal of Biological Chemistry. 290: 10544-54. PMID 25716316 DOI: 10.1074/jbc.M115.641803  1
2015 Kuo IY, Ehrlich BE. Muscling in on the ryanodine receptor. Nature Structural & Molecular Biology. 22: 106-7. PMID 25650905 DOI: 10.1038/nsmb.2960  1
2015 Kuo IY, Ehrlich BE. Signaling in muscle contraction. Cold Spring Harbor Perspectives in Biology. 7: a006023. PMID 25646377 DOI: 10.1101/cshperspect.a006023  1
2015 Kuo IY, Hu J, Ha Y, Ehrlich BE. Presenilin-like GxGD membrane proteases have dual roles as proteolytic enzymes and ion channels. The Journal of Biological Chemistry. 290: 6419-27. PMID 25609250 DOI: 10.1074/jbc.M114.629584  1
2014 Kuo IY, Kwaczala AT, Nguyen L, Russell KS, Campbell SG, Ehrlich BE. Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 111: 16604-9. PMID 25368166 DOI: 10.1073/pnas.1415933111  1
2014 Cai Y, Fedeles SV, Dong K, Anyatonwu G, Onoe T, Mitobe M, Gao JD, Okuhara D, Tian X, Gallagher AR, Tang Z, Xie X, Lalioti MD, Lee AH, Ehrlich BE, et al. Altered trafficking and stability of polycystins underlie polycystic kidney disease. The Journal of Clinical Investigation. 124: 5129-44. PMID 25365220 DOI: 10.1172/JCI67273  1
2014 Feriod CN, Nguyen L, Jurczak MJ, Kruglov EA, Nathanson MH, Shulman GI, Bennett AM, Ehrlich BE. Inositol 1,4,5-trisphosphate receptor type II (InsP3R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP3R-II. American Journal of Physiology. Endocrinology and Metabolism. 307: E1057-64. PMID 25315698 DOI: 10.1152/ajpendo.00236.2014  1
2014 Kuo IY, DesRochers TM, Kimmerling EP, Nguyen L, Ehrlich BE, Kaplan DL. Cyst formation following disruption of intracellular calcium signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 14283-8. PMID 25228769 DOI: 10.1073/pnas.1412323111  1
2014 Kuo IY, Keeler C, Corbin R, Ćelić A, Petri ET, Hodsdon ME, Ehrlich BE. The number and location of EF hand motifs dictates the calcium dependence of polycystin-2 function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2332-46. PMID 24558196 DOI: 10.1096/fj.13-247106  1
2013 Keeler C, Poon G, Kuo IY, Ehrlich BE, Hodsdon ME. An explicit formulation approach for the analysis of calcium binding to EF-hand proteins using isothermal titration calorimetry. Biophysical Journal. 105: 2843-53. PMID 24359756 DOI: 10.1016/j.bpj.2013.11.017  1
2013 Mo M, Hoang HT, Schmidt S, Clark RB, Ehrlich BE. The role of chromogranin B in an animal model of multiple sclerosis. Molecular and Cellular Neurosciences. 56: 102-14. PMID 23624073 DOI: 10.1016/j.mcn.2013.04.003  1
2013 Paavola J, Schliffke S, Rossetti S, Kuo IY, Yuan S, Sun Z, Harris PC, Torres VE, Ehrlich BE. Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 58: 199-208. PMID 23376035 DOI: 10.1016/j.yjmcc.2013.01.015  1
2012 Benbow JH, Mann T, Keeler C, Fan C, Hodsdon ME, Lolis E, DeGray B, Ehrlich BE. Inhibition of paclitaxel-induced decreases in calcium signaling. The Journal of Biological Chemistry. 287: 37907-16. PMID 22988235 DOI: 10.1074/jbc.M112.385070  1
2012 Yoshiba S, Shiratori H, Kuo IY, Kawasumi A, Shinohara K, Nonaka S, Asai Y, Sasaki G, Belo JA, Sasaki H, Nakai J, Dworniczak B, Ehrlich BE, Pennekamp P, Hamada H. Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2. Science (New York, N.Y.). 338: 226-31. PMID 22983710 DOI: 10.1126/science.1222538  1
2012 Mo M, Erdelyi I, Szigeti-Buck K, Benbow JH, Ehrlich BE. Prevention of paclitaxel-induced peripheral neuropathy by lithium pretreatment. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4696-709. PMID 22889832 DOI: 10.1096/fj.12-214643  1
2012 Zhang HS, Liu D, Huang Y, Schmidt S, Hickey R, Guschin D, Su H, Jovin IS, Kunis M, Hinkley S, Liang Y, Hinh L, Spratt SK, Case CC, Rebar EJ, ... Ehrlich BE, ... ... Ehrlich B, et al. A designed zinc-finger transcriptional repressor of phospholamban improves function of the failing heart. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1508-15. PMID 22828502 DOI: 10.1038/mt.2012.80  1
2012 Kuo IY, Ehrlich BE. Ion channels in renal disease. Chemical Reviews. 112: 6353-72. PMID 22809040 DOI: 10.1021/cr3001077  1
2012 Ćelić AS, Petri ET, Benbow J, Hodsdon ME, Ehrlich BE, Boggon TJ. Calcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating. The Journal of Biological Chemistry. 287: 17232-40. PMID 22474326 DOI: 10.1074/jbc.M112.354613  1
2012 Lee MY, Sun B, Schliffke S, Yue Z, Ye M, Paavola J, Bozkulak EC, Amos PJ, Ren Y, Ju R, Jung YW, Ge X, Yue L, Ehrlich BE, Qyang Y. Derivation of functional ventricular cardiomyocytes using endogenous promoter sequence from murine embryonic stem cells. Stem Cell Research. 8: 49-57. PMID 22099020 DOI: 10.1016/j.scr.2011.08.004  1
2011 Lee MY, Cagavi Bozkulak E, Schliffke S, Amos PJ, Ren Y, Ge X, Ehrlich BE, Qyang Y. High density cultures of embryoid bodies enhanced cardiac differentiation of murine embryonic stem cells. Biochemical and Biophysical Research Communications. 416: 51-7. PMID 22079290 DOI: 10.1016/j.bbrc.2011.10.140  1
2011 Schmidt S, Mo M, Heidrich FM, Ćelić A, Ehrlich BE. C-terminal domain of chromogranin B regulates intracellular calcium signaling. The Journal of Biological Chemistry. 286: 44888-96. PMID 22016391 DOI: 10.1074/jbc.M111.251330  1
2011 Schulze C, McGowan M, Jordt SE, Ehrlich BE. Prolonged oxaliplatin exposure alters intracellular calcium signaling: a new mechanism to explain oxaliplatin-associated peripheral neuropathy. Clinical Colorectal Cancer. 10: 126-33. PMID 21859566 DOI: 10.1016/j.clcc.2011.03.010  1
2011 Benbow JH, DeGray B, Ehrlich BE. Protection of neuronal calcium sensor 1 protein in cells treated with paclitaxel. The Journal of Biological Chemistry. 286: 34575-82. PMID 21808066 DOI: 10.1074/jbc.M111.265751  1
2011 Ren Y, Lee MY, Schliffke S, Paavola J, Amos PJ, Ge X, Ye M, Zhu S, Senyei G, Lum L, Ehrlich BE, Qyang Y. Small molecule Wnt inhibitors enhance the efficiency of BMP-4-directed cardiac differentiation of human pluripotent stem cells. Journal of Molecular and Cellular Cardiology. 51: 280-7. PMID 21569778 DOI: 10.1016/j.yjmcc.2011.04.012  1
2011 Bimboese P, Gibson CJ, Schmidt S, Xiang W, Ehrlich BE. Isoform-specific regulation of the inositol 1,4,5-trisphosphate receptor by O-linked glycosylation. The Journal of Biological Chemistry. 286: 15688-97. PMID 21383013 DOI: 10.1074/jbc.M110.206482  1
2010 Schmidt S, Ehrlich BE. Unloading intracellular calcium stores reveals regionally specific functions. Neuron. 68: 806-8. PMID 21144994 DOI: 10.1016/j.neuron.2010.11.039  1
2010 Zhang K, Heidrich FM, DeGray B, Boehmerle W, Ehrlich BE. Paclitaxel accelerates spontaneous calcium oscillations in cardiomyocytes by interacting with NCS-1 and the InsP3R. Journal of Molecular and Cellular Cardiology. 49: 829-35. PMID 20801127 DOI: 10.1016/j.yjmcc.2010.08.018  1
2010 Petri ET, Celic A, Kennedy SD, Ehrlich BE, Boggon TJ, Hodsdon ME. Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity. Proceedings of the National Academy of Sciences of the United States of America. 107: 9176-81. PMID 20439752 DOI: 10.1073/pnas.0912295107  1
2009 Blachford C, Celić A, Petri ET, Ehrlich BE. Discrete proteolysis of neuronal calcium sensor-1 (NCS-1) by mu-calpain disrupts calcium binding. Cell Calcium. 46: 257-62. PMID 19732951 DOI: 10.1016/j.ceca.2009.08.002  1
2009 Casuscelli J, Schmidt S, DeGray B, Petri ET, Celić A, Folta-Stogniew E, Ehrlich BE, Boggon TJ. Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2. American Journal of Physiology. Renal Physiology. 297: F1310-5. PMID 19726544 DOI: 10.1152/ajprenal.00412.2009  1
2009 Collin T, Franconville R, Ehrlich BE, Llano I. Activation of metabotropic glutamate receptors induces periodic burst firing and concomitant cytosolic Ca2+ oscillations in cerebellar interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9281-91. PMID 19625518 DOI: 10.1523/JNEUROSCI.1865-09.2009  1
2009 Heidrich FM, Ehrlich BE. Calcium, calpains, and cardiac hypertrophy: a new link. Circulation Research. 104: e19-20. PMID 19179660 DOI: 10.1161/CIRCRESAHA.108.191072  1
2008 Geng L, Boehmerle W, Maeda Y, Okuhara DY, Tian X, Yu Z, Choe CU, Anyatonwu GI, Ehrlich BE, Somlo S. Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2. Proceedings of the National Academy of Sciences of the United States of America. 105: 15920-5. PMID 18836075 DOI: 10.1073/pnas.0805062105  1
2008 Celić A, Petri ET, Demeler B, Ehrlich BE, Boggon TJ. Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis. The Journal of Biological Chemistry. 283: 28305-12. PMID 18694932 DOI: 10.1074/jbc.M802743200  1
2008 Heidrich FM, Zhang K, Estrada M, Huang Y, Giordano FJ, Ehrlich BE. Chromogranin B regulates calcium signaling, nuclear factor kappaB activity, and brain natriuretic peptide production in cardiomyocytes. Circulation Research. 102: 1230-8. PMID 18420944 DOI: 10.1161/CIRCRESAHA.107.166033  1
2008 Gibson CJ, Ehrlich BE. Inositol 1,4,5-trisphosphate receptor movement is restricted by addition of elevated levels of O-linked sugar. Cell Calcium. 43: 228-35. PMID 17610951 DOI: 10.1016/j.ceca.2007.05.008  1
2007 Jordt SE, Ehrlich BE. TRP channels in disease. Sub-Cellular Biochemistry. 45: 253-71. PMID 18193640  1
2007 Rengifo J, Gibson CJ, Winkler E, Collin T, Ehrlich BE. Regulation of the inositol 1,4,5-trisphosphate receptor type I by O-GlcNAc glycosylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13813-21. PMID 18077693 DOI: 10.1523/JNEUROSCI.2069-07.2007  1
2007 Minagawa N, Nagata J, Shibao K, Masyuk AI, Gomes DA, Rodrigues MA, Lesage G, Akiba Y, Kaunitz JD, Ehrlich BE, Larusso NF, Nathanson MH. Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile. Gastroenterology. 133: 1592-602. PMID 17916355 DOI: 10.1053/j.gastro.2007.08.020  1
2007 Boehmerle W, Zhang K, Sivula M, Heidrich FM, Lee Y, Jordt SE, Ehrlich BE. Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation. Proceedings of the National Academy of Sciences of the United States of America. 104: 11103-8. PMID 17581879 DOI: 10.1073/pnas.0701546104  1
2007 Nicolay NH, Hertle D, Boehmerle W, Heidrich FM, Yeckel M, Ehrlich BE. Inositol 1,4,5 trisphosphate receptor and chromogranin B are concentrated in different regions of the hippocampus. Journal of Neuroscience Research. 85: 2026-36. PMID 17471556 DOI: 10.1002/jnr.21328  1
2007 Anyatonwu GI, Estrada M, Tian X, Somlo S, Ehrlich BE. Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. Proceedings of the National Academy of Sciences of the United States of America. 104: 6454-9. PMID 17404231 DOI: 10.1073/pnas.0610324104  1
2006 Choe CU, Ehrlich BE. The inositol 1,4,5-trisphosphate receptor (IP3R) and its regulators: sometimes good and sometimes bad teamwork. Science's Stke : Signal Transduction Knowledge Environment. 2006: re15. PMID 17132820 DOI: 10.1126/stke.3632006re15  1
2006 Estrada M, Varshney A, Ehrlich BE. Elevated testosterone induces apoptosis in neuronal cells. The Journal of Biological Chemistry. 281: 25492-501. PMID 16803879 DOI: 10.1074/jbc.M603193200  1
2006 Minagawa N, Ehrlich BE, Nathanson MH. Calcium signaling in cholangiocytes. World Journal of Gastroenterology : Wjg. 12: 3466-70. PMID 16773703  1
2006 Schlecker C, Boehmerle W, Jeromin A, DeGray B, Varshney A, Sharma Y, Szigeti-Buck K, Ehrlich BE. Neuronal calcium sensor-1 enhancement of InsP3 receptor activity is inhibited by therapeutic levels of lithium. The Journal of Clinical Investigation. 116: 1668-74. PMID 16691292 DOI: 10.1172/JCI22466  1
2006 Gibson TB, Lawrence MC, Gibson CJ, Vanderbilt CA, McGlynn K, Arnette D, Chen W, Collins J, Naziruddin B, Levy MF, Ehrlich BE, Cobb MH. Inhibition of glucose-stimulated activation of extracellular signal-regulated protein kinases 1 and 2 by epinephrine in pancreatic beta-cells. Diabetes. 55: 1066-73. PMID 16567530 DOI: 10.2337/diabetes.55.04.06.db05-1266  1
2006 Uhlén P, Burch PM, Zito CI, Estrada M, Ehrlich BE, Bennett AM. Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 2160-5. PMID 16461457 DOI: 10.1073/pnas.0510876103  1
2006 Estrada M, Uhlen P, Ehrlich BE. Ca2+ oscillations induced by testosterone enhance neurite outgrowth. Journal of Cell Science. 119: 733-43. PMID 16449326 DOI: 10.1242/jcs.02775  1
2006 Marius P, Guerra MT, Nathanson MH, Ehrlich BE, Leite MF. Calcium release from ryanodine receptors in the nucleoplasmic reticulum. Cell Calcium. 39: 65-73. PMID 16289270 DOI: 10.1016/j.ceca.2005.09.010  1
2006 Marius P, Guerra MT, Nathanson MH, Ehrlich BE, Leite MF. Corrigendum to "Calcium release from ryanodine receptors in the nucleoplasmic reticulum" [Cell Calcium 39 (2006) 65-73] (DOI:10.1016/j.ceca.2005.09.010) Cell Calcium. 39: 551. DOI: 10.1016/j.ceca.2006.02.001  1
2005 Anyatonwu GI, Ehrlich BE. Organic cation permeation through the channel formed by polycystin-2. The Journal of Biological Chemistry. 280: 29488-93. PMID 15961385 DOI: 10.1074/jbc.M504359200  1
2005 Zielinski CE, Jacob SN, Bouzahzah F, Ehrlich BE, Craft J. Naive CD4+ T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation. Journal of Immunology (Baltimore, Md. : 1950). 174: 5100-9. PMID 15814741  1
2005 Jacob SN, Choe CU, Uhlen P, DeGray B, Yeckel MF, Ehrlich BE. Signaling microdomains regulate inositol 1,4,5-trisphosphate-mediated intracellular calcium transients in cultured neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2853-64. PMID 15772345 DOI: 10.1523/JNEUROSCI.4313-04.2005  1
2004 Anyatonwu GI, Ehrlich BE. Calcium signaling and polycystin-2. Biochemical and Biophysical Research Communications. 322: 1364-73. PMID 15336985 DOI: 10.1016/j.bbrc.2004.08.043  1
2004 Choe CU, Harrison KD, Grant W, Ehrlich BE. Functional coupling of chromogranin with the inositol 1,4,5-trisphosphate receptor shapes calcium signaling. The Journal of Biological Chemistry. 279: 35551-6. PMID 15194698 DOI: 10.1074/jbc.M311261200  1
2004 Johenning FW, Wenk MR, Uhlén P, Degray B, Lee E, De Camilli P, Ehrlich BE. InsP3-mediated intracellular calcium signalling is altered by expression of synaptojanin-1. The Biochemical Journal. 382: 687-94. PMID 15080793 DOI: 10.1042/BJ20040418  1
2004 Cai Y, Anyatonwu G, Okuhara D, Lee KB, Yu Z, Onoe T, Mei CL, Qian Q, Geng L, Wiztgall R, Ehrlich BE, Somlo S. Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812. The Journal of Biological Chemistry. 279: 19987-95. PMID 14742446 DOI: 10.1074/jbc.M312031200  1
2003 Thrower EC, Choe CU, So SH, Jeon SH, Ehrlich BE, Yoo SH. A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel. The Journal of Biological Chemistry. 278: 49699-706. PMID 14506248 DOI: 10.1074/jbc.M309307200  1
2003 Anyatonwu GI, Buck ED, Ehrlich BE. Methanethiosulfonate ethylammonium block of amine currents through the ryanodine receptor reveals single pore architecture. The Journal of Biological Chemistry. 278: 45528-38. PMID 12963712 DOI: 10.1074/jbc.M307863200  1
2003 Varshney A, Ehrlich BE. Intracellular Ca2+ signaling and human disease: the hunt begins with Huntington's. Neuron. 39: 195-7. PMID 12873376 DOI: 10.1016/S0896-6273(03)00425-2  1
2003 Leite MF, Thrower EC, Echevarria W, Koulen P, Hirata K, Bennett AM, Ehrlich BE, Nathanson MH. Nuclear and cytosolic calcium are regulated independently. Proceedings of the National Academy of Sciences of the United States of America. 100: 2975-80. PMID 12606721 DOI: 10.1073/pnas.0536590100  1
2002 Jiang QX, Thrower EC, Chester DW, Ehrlich BE, Sigworth FJ. Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution. The Embo Journal. 21: 3575-81. PMID 12110570 DOI: 10.1093/emboj/cdf380  1
2002 Johenning FW, Zochowski M, Conway SJ, Holmes AB, Koulen P, Ehrlich BE. Distinct intracellular calcium transients in neurites and somata integrate neuronal signals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5344-53. PMID 12097486  1
2002 O'Neill AF, Hagar RE, Zipfel WR, Nathanson MH, Ehrlich BE. Regulation of the type III InsP(3) receptor by InsP(3) and calcium. Biochemical and Biophysical Research Communications. 294: 719-25. PMID 12056830 DOI: 10.1016/S0006-291X(02)00524-7  1
2002 Pusl T, Wu JJ, Zimmerman TL, Zhang L, Ehrlich BE, Berchtold MW, Hoek JB, Karpen SJ, Nathanson MH, Bennett AM. Epidermal growth factor-mediated activation of the ETS domain transcription factor Elk-1 requires nuclear calcium. The Journal of Biological Chemistry. 277: 27517-27. PMID 11971908 DOI: 10.1074/jbc.M203002200  1
2002 Johenning FW, Ehrlich BE. Signaling microdomains: InsP(3) receptor localization takes on new meaning. Neuron. 34: 173-5. PMID 11970857 DOI: 10.1016/S0896-6273(02)00665-7  1
2002 Koulen P, Cai Y, Geng L, Maeda Y, Nishimura S, Witzgall R, Ehrlich BE, Somlo S. Polycystin-2 is an intracellular calcium release channel. Nature Cell Biology. 4: 191-7. PMID 11854751 DOI: 10.1038/ncb754  1
2002 Thrower EC, Park HY, So SH, Yoo SH, Ehrlich BE. Activation of the inositol 1,4,5-trisphosphate receptor by the calcium storage protein chromogranin A. The Journal of Biological Chemistry. 277: 15801-6. PMID 11842082 DOI: 10.1074/jbc.M110139200  1
2001 Thrower EC, Hagar RE, Ehrlich BE. Regulation of Ins(1,4,5)P3 receptor isoforms by endogenous modulators. Trends in Pharmacological Sciences. 22: 580-6. PMID 11698102 DOI: 10.1016/S0165-6147(00)01809-5  1
2001 Koulen P, Janowitz T, Johenning FW, Ehrlich BE. Characterization of the calcium-release channel/ryanodine receptor from zebrafish skeletal muscle. The Journal of Membrane Biology. 183: 155-63. PMID 11696857 DOI: 10.1007/s00232-001-0063-8  1
2001 Somlo S, Ehrlich B. Human disease: Calcium signaling in polycystic kidney disease Current Biology. 11: R356-R360. PMID 11369247 DOI: 10.1016/S0960-9822(01)00193-2  1
2000 Hagar RE, Ehrlich BE. Regulation of the type III InsP3 receptor and its role in beta cell function. Cellular and Molecular Life Sciences : Cmls. 57: 1938-49. PMID 11215519  1
2000 Koulen P, Janowitz T, Johnston LD, Ehrlich BE. Conservation of localization patterns of IP(3) receptor type 1 in cerebellar Purkinje cells across vertebrate species. Journal of Neuroscience Research. 61: 493-9. PMID 10956418 DOI: 10.1002/1097-4547(20000901)61:5<493::AID-JNR3>3.0.CO;2-9  1
2000 Koulen P, Ehrlich BE. Reversible block of the calcium release channel/ryanodine receptor by protamine, a heparin antidote. Molecular Biology of the Cell. 11: 2213-9. PMID 10888663  1
2000 Hagar RE, Ehrlich BE. Regulation of the type III InsP(3) receptor by InsP(3) and ATP. Biophysical Journal. 79: 271-8. PMID 10866953 DOI: 10.1016/S0006-3495(00)76289-8  1
1999 Moraru II, Kaftan EJ, Ehrlich BE, Watras J. Regulation of type 1 inositol 1,4,5-trisphosphate-gated calcium channels by InsP3 and calcium: Simulation of single channel kinetics based on ligand binding and electrophysiological analysis. The Journal of General Physiology. 113: 837-49. PMID 10352034 DOI: 10.1085/jgp.113.6.837  1
1999 Zecevic N, Milosevic A, Ehrlich BE. Calcium signaling molecules in human cerebellum at midgestation and in ataxia. Early Human Development. 54: 103-16. PMID 10213289 DOI: 10.1016/S0378-3782(98)00090-5  1
1998 Quinn KE, Castellani L, Ondrias K, Ehrlich BE. Characterization of the ryanodine receptor/channel of invertebrate muscle. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 274: R494-R502. PMID 29587041 DOI: 10.1152/ajpregu.1998.274.2.R494  0.92
1998 Hagar RE, Burgstahler AD, Nathanson MH, Ehrlich BE. Type III InsP3 receptor channel stays open in the presence of increased calcium. Nature. 396: 81-4. PMID 9817204 DOI: 10.1038/23954  1
1998 Quinn KE, Castellani L, Ondrias K, Ehrlich BE. Characterization of the ryanodine receptor/channel of invertebrate muscle. The American Journal of Physiology. 274: R494-502. PMID 9486309  1
1997 Kaftan EJ, Ehrlich BE, Watras J. Inositol 1,4,5-trisphosphate (InsP3) and calcium interact to increase the dynamic range of InsP3 receptor-dependent calcium signaling. The Journal of General Physiology. 110: 529-38. PMID 9348325 DOI: 10.1085/jgp.110.5.529  1
1997 Striggow F, Ehrlich BE. Regulation of intracellular calcium release channel function by arachidonic acid and leukotriene B4. Biochemical and Biophysical Research Communications. 237: 413-8. PMID 9268725 DOI: 10.1006/bbrc.1997.7152  1
1997 Quinn KE, Ehrlich BE. Methanethiosulfonate derivatives inhibit current through the ryanodine receptor/channel. The Journal of General Physiology. 109: 255-64. PMID 9041453 DOI: 10.1085/jgp.109.2.255  1
1996 Striggow F, Ehrlich BE. The inositol 1,4,5-trisphosphate receptor of cerebellum. Mn2+ permeability and regulation by cytosolic Mn2+. The Journal of General Physiology. 108: 115-24. PMID 8854341  1
1996 Ondrias K, Brillantes AM, Scott A, Ehrlich BE, Marks AR. Single channel properties and calcium conductance of the cloned expressed ryanodine receptor/calcium-release channel. Society of General Physiologists Series. 51: 29-45. PMID 8809932  1
1996 Striggow F, Ehrlich BE. Ligand-gated calcium channels inside and out. Current Opinion in Cell Biology. 8: 490-5. PMID 8791458 DOI: 10.1016/S0955-0674(96)80025-1  1
1996 Kaftan E, Marks AR, Ehrlich BE. Effects of rapamycin on ryanodine receptor/Ca(2+)-release channels from cardiac muscle. Circulation Research. 78: 990-7. PMID 8635249  1
1995 Ehrlich BE. Functional properties of intracellular calcium-release channels. Current Opinion in Neurobiology. 5: 304-9. PMID 7580152 DOI: 10.1016/0959-4388(95)80042-5  1
1995 Bezprozvanny I, Ehrlich BE. The inositol 1,4,5-trisphosphate (InsP3) receptor. The Journal of Membrane Biology. 145: 205-16. PMID 7563022 DOI: 10.1007/BF00232713  1
1994 Bezprozvanny I, Bezprozvannaya S, Ehrlich BE. Caffeine-induced inhibition of inositol(1,4,5)-trisphosphate-gated calcium channels from cerebellum. Molecular Biology of the Cell. 5: 97-103. PMID 8186468  1
1994 Ehrlich BE, Bezprozvanny I. Intracellular calcium release channels. The Chinese Journal of Physiology. 37: 1-7. PMID 7956507  1
1994 Bezprozvanny I, Ehrlich BE. Inositol (1,4,5)-trisphosphate (InsP3)-gated Ca channels from cerebellum: conduction properties for divalent cations and regulation by intraluminal calcium. The Journal of General Physiology. 104: 821-56. PMID 7876825  1
1994 Ehrlich BE, Kaftan E, Bezprozvannaya S, Bezprozvanny I. The pharmacology of intracellular Ca(2+)-release channels. Trends in Pharmacological Sciences. 15: 145-9. PMID 7754532 DOI: 10.1016/0165-6147(94)90074-4  1
1994 Brillantes AB, Ondrias K, Scott A, Kobrinsky E, Ondriasová E, Moschella MC, Jayaraman T, Landers M, Ehrlich BE, Marks AR. Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein. Cell. 77: 513-23. PMID 7514503 DOI: 10.1016/0092-8674(94)90214-3  1
1993 Bernal J, Ehrlich BE. Guanine nucleotides modulate calcium currents in a marine Paramecium. The Journal of Experimental Biology. 176: 117-33. PMID 8386740  1
1993 Bezprozvanny I, Ehrlich BE. ATP modulates the function of inositol 1,4,5-trisphosphate-gated channels at two sites. Neuron. 10: 1175-84. PMID 7686381 DOI: 10.1016/0896-6273(93)90065-Y  1
1993 Bezprozvanny IB, Ondrias K, Kaftan E, Stoyanovsky DA, Ehrlich BE. Activation of the calcium release channel (ryanodine receptor) by heparin and other polyanions is calcium dependent. Molecular Biology of the Cell. 4: 347-52. PMID 7683508  1
1992 Ehrlich BE. Planar lipid bilayers on patch pipettes: bilayer formation and ion channel incorporation. Methods in Enzymology. 207: 463-70. PMID 1382197  1
1991 Bernal J, Kelsey AM, Ehrlich BE. GTP-gamma-S increases the duration of backward swimming behavior and the calcium action potential in marine Paramecium. The Journal of Experimental Biology. 155: 505-18. PMID 1849956  1
1991 Watras J, Bezprozvanny I, Ehrlich BE. Inositol 1,4,5-trisphosphate-gated channels in cerebellum: presence of multiple conductance states. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3239-45. PMID 1719158  1
1991 Lee YS, Ondrias K, Duhl AJ, Ehrlich BE, Kim DH. Comparison of calcium release from sarcoplasmic reticulum of slow and fast twitch muscles. The Journal of Membrane Biology. 122: 155-63. PMID 1716686 DOI: 10.1007/BF01872638  1
1991 Borgatta L, Watras J, Katz AM, Ehrlich BE. Regional differences in calcium-release channels from heart. Proceedings of the National Academy of Sciences of the United States of America. 88: 2486-9. PMID 1706525  1
1991 Bezprozvanny I, Watras J, Ehrlich BE. Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature. 351: 751-4. PMID 1648178 DOI: 10.1038/351751a0  1
1990 Ondrias K, Borgatta L, Kim DH, Ehrlich BE. Biphasic effects of doxorubicin on the calcium release channel from sarcoplasmic reticulum of cardiac muscle. Circulation Research. 67: 1167-74. PMID 2171802  1
1988 Ehrlich BE, Watras J. Inositol 1,4,5-trisphosphate activates a channel from smooth muscle sarcoplasmic reticulum. Nature. 336: 583-6. PMID 2849060 DOI: 10.1038/336583a0  1
1988 Ehrlich BE, Jacobson AR, Hinrichsen R, Sayre LM, Forte MA. Paramecium calcium channels are blocked by a family of calmodulin antagonists. Proceedings of the National Academy of Sciences of the United States of America. 85: 5718-22. PMID 2456578  1
1986 Ehrlich BE, Schen CR, Garcia ML, Kaczorowski GJ. Incorporation of calcium channels from cardiac sarcolemmal membrane vesicles into planar lipid bilayers. Proceedings of the National Academy of Sciences of the United States of America. 83: 193-7. PMID 2417238  1
1985 Hoch DH, Romero-Mira M, Ehrlich BE, Finkelstein A, DasGupta BR, Simpson LL. Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes. Proceedings of the National Academy of Sciences of the United States of America. 82: 1692-6. PMID 3856850 DOI: 10.1073/pnas.82.6.1692  1
1984 Ehrlich BE, Clausen C, Gosenfeld LF, Diamond JM. Lithium concentration in the muscle compartment of manic-depressive patients during lithium therapy. Journal of Psychiatric Research. 18: 139-48. PMID 6747912 DOI: 10.1016/0022-3956(84)90005-0  1
1984 Ehrlich BE, Schen CR, Spudich JL. Bacterial rhodopsins monitored with fluorescent dyes in vesicles and in vivo. The Journal of Membrane Biology. 82: 89-94. PMID 6502700 DOI: 10.1007/BF01870735  1
1984 Ehrlich BE, Finkelstein A, Forte M, Kung C. Voltage-dependent calcium channels from Paramecium cilia incorporated into planar lipid bilayers. Science (New York, N.Y.). 225: 427-8. PMID 6330895  1
1984 Ehrlich BE, Russell JM. Lithium transport across squid axon membrane. Brain Research. 311: 141-3. PMID 6091848 DOI: 10.1016/0006-8993(84)91406-9  1
1983 Diamond JM, Ehrlich BE, Morawski SG, Santa Ana CA, Fordtran JS. Lithium absorption in tight and leaky segments of intestine. The Journal of Membrane Biology. 72: 153-9. PMID 6854620 DOI: 10.1007/BF01870322  1
1983 Ehrlich BE, Diamond JM, Fry V, Meier K. Lithium's inhibition of erythrocyte cation countertransport involves a slow process in the erythrocyte. The Journal of Membrane Biology. 75: 233-40. PMID 6631944 DOI: 10.1007/BF01871954  1
1983 Clausen C, Ehrlich BE, Diamond JM, Gosenfeld LF. Muscle lithium in manic-depressive patients during lithium therapy. The New England Journal of Medicine. 309: 190. PMID 6408477 DOI: 10.1056/NEJM198307213090321  1
1983 Ehrlich BE, Diamond JM. Lithium absorption: implications for sustained-release lithium preparations. Lancet. 1: 306. PMID 6130326  1
1982 Diamond JM, Ehrlich BE, Freedman JC. A slow process in the effect of lithium therapy on countertransport. The New England Journal of Medicine. 307: 1646. PMID 7144858 DOI: 10.1056/NEJM198212233072617  1
1982 Ehrlich BE, Wright EM. Choline and PAH transport across blood-CSF barriers: the effect of lithium. Brain Research. 250: 245-9. PMID 6293641 DOI: 10.1016/0006-8993(82)90418-8  1
1981 Modlin IM, Ehrlich BE, Lamers CB, Diamond JM, Walsh JH. Variable effect of lithium on canine pancreatic polypeptide and gastrin release by a meal or bombesin. Digestion. 22: 177-84. PMID 7308590 DOI: 10.1159/000198642  1
1981 Ehrlich BE, Diamond JM, Gosenfeld L. Lithium-induced changes in sodium-lithium countertransport. Biochemical Pharmacology. 30: 2539-43. PMID 7306206 DOI: 10.1016/0006-2952(81)90580-3  1
1981 Ehrlich BE, Russell JM. Lithium fluxes across squid axon membrane Biophysical Journal. 33: M-AM-Po91.  1
1980 Ehrlich BE, Diamond JM, Braun LD, Cornford EM, Oldendorf WH. Effects of lithium on blood-brain barrier transport of the neurotransmitter precursors choline, tyrosine and tryptophan. Brain Research. 193: 604-7. PMID 7388615 DOI: 10.1016/0006-8993(80)90198-5  1
1980 Ehrlich BE, Clausen C, Diamond JM. Lithium pharmacokinetics: single-dose experiments and analysis using a physiological model. Journal of Pharmacokinetics and Biopharmaceutics. 8: 439-61. PMID 7252790 DOI: 10.1007/BF01059545  1
1980 Ehrlich BE, Diamond JM. Lithium, membranes, and manic-depressive illness. The Journal of Membrane Biology. 52: 187-200. PMID 6991708 DOI: 10.1007/BF01869189  1
1980 Jope RS, Jenden DJ, Ehrlich BE, Diamond JM, Gosenfeld LF. Erythrocyte choline concentrations are elevated in manic patients. Proceedings of the National Academy of Sciences of the United States of America. 77: 6144-6. PMID 6934541 DOI: 10.1073/pnas.77.10.6144  1
1980 Ehrlich BE, Gosenfeld L, Diamond JM. A kinetic analysis of lithium-induced changes in lithium transport across erythrocyte membranes Federation Proceedings. 39: 3626.  1
1979 Ehrlich BE, Diamond JM, Kaye W, Ornitz EM, Gosenfeld L. Lithium transport in erythrocytes from a pair of twins with manic disorder. The American Journal of Psychiatry. 136: 1477-8. PMID 495808  1
1979 Ehrlich BE, Diamond JM. Lithium fluxes in human erythrocytes. The American Journal of Physiology. 237: C102-10. PMID 464037  1
1978 Ehrlich BE, Diamond JM. An ultramicro method for analysis of lithium and other biologically important cations. Biochimica Et Biophysica Acta. 543: 264-8. PMID 728464 DOI: 10.1016/0304-4165(78)90072-7  1
1978 Jope RS, Jenden DJ, Ehrlich BE, Diamond JM. Choline accumulates in erythrocytes during lithium therapy. The New England Journal of Medicine. 299: 833-4. PMID 692570  1
1978 Ehrlich BE, Diamond JM, Gosenfeld L, Kaufman-Diamond S. Lithium, membranes, and manic-depressive illness [proceedings]. Psychopharmacology Bulletin. 14: 21-2. PMID 674530  1
1978 Ehrlich BE, Cserr HF. Comparative aspects of brain barrier systems for iodide. The American Journal of Physiology. 234: R61-5. PMID 623285  1
1978 Ehrlich BE, Clausen C, Diamond JM. Lithium (Li+) pharmacokinetics in manic-depressive patients: Experiments and a model Federation Proceedings. 37: No. 3676.  1
1977 Ehrlich BE, Diamond JM. Lithium transport across the red blood cell membrane Federation Proceedings. 36: No. 7.  1
1977 Cserr HF, Ehrlich BE. Active transport of iodide by choroid plexus: a phylogenetic survey Federation Proceedings. 36: No. 1424.  1
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