| Year |
Citation |
Score |
| 2023 |
Fahlke C, Machtens JP, Sandtner W, Schicker K, Sun H. Editorial: Combining computational and experimental approaches to characterize ion channels and transporters. Frontiers in Physiology. 14: 1320336. PMID 38028804 DOI: 10.3389/fphys.2023.1320336 |
0.36 |
|
| 2023 |
Suslova M, Kortzak D, Machtens JP, Kovermann P, Fahlke C. state pore opening as functional basis of increased EAAT anion channel activity in episodic ataxia 6. Frontiers in Physiology. 14: 1147216. PMID 37538371 DOI: 10.3389/fphys.2023.1147216 |
0.818 |
|
| 2023 |
Kolen B, Borghans B, Kortzak D, Lugo V, Hannack C, Guzman RE, Ullah G, Fahlke C. Vesicular glutamate transporters are H-anion exchangers that operate at variable stoichiometry. Nature Communications. 14: 2723. PMID 37169755 DOI: 10.1038/s41467-023-38340-9 |
0.476 |
|
| 2022 |
Guzman RE, Sierra-Marquez J, Bungert-Plümke S, Franzen A, Fahlke C. Functional Characterization of Variants Associated With X-Linked Intellectual Disability and Epilepsy. Frontiers in Molecular Neuroscience. 15: 872407. PMID 35721313 DOI: 10.3389/fnmol.2022.872407 |
0.357 |
|
| 2022 |
Kovermann P, Engels M, Müller F, Fahlke C. Cellular Physiology and Pathophysiology of EAAT Anion Channels. Frontiers in Cellular Neuroscience. 15: 815279. PMID 35087380 DOI: 10.3389/fncel.2021.815279 |
0.569 |
|
| 2021 |
Kovermann P, Kolobkova Y, Franzen A, Fahlke C. Mutations associated with epileptic encephalopathy modify EAAT2 anion channel function. Epilepsia. PMID 34961934 DOI: 10.1111/epi.17154 |
0.493 |
|
| 2021 |
Gehlen J, Aretzweiler C, Mataruga A, Fahlke C, Müller F. Excitatory amino acid transporter EAAT5 improves temporal resolution in the retina. Eneuro. PMID 34772693 DOI: 10.1523/ENEURO.0406-21.2021 |
0.396 |
|
| 2021 |
Engels M, Kalia M, Rahmati S, Petersilie L, Kovermann P, van Putten MJAM, Rose CR, Meijer HGE, Gensch T, Fahlke C. Glial Chloride Homeostasis Under Transient Ischemic Stress. Frontiers in Cellular Neuroscience. 15: 735300. PMID 34602981 DOI: 10.3389/fncel.2021.735300 |
0.367 |
|
| 2021 |
Alleva C, Machtens JP, Kortzak D, Weyand I, Fahlke C. Molecular Basis of Coupled Transport and Anion Conduction in Excitatory Amino Acid Transporters. Neurochemical Research. PMID 33587237 DOI: 10.1007/s11064-021-03252-x |
0.803 |
|
| 2020 |
Alleva C, Kovalev K, Astashkin R, Berndt MI, Baeken C, Balandin T, Gordeliy V, Fahlke C, Machtens JP. Na-dependent gate dynamics and electrostatic attraction ensure substrate coupling in glutamate transporters. Science Advances. 6. PMID 33208356 DOI: 10.1126/sciadv.aba9854 |
0.391 |
|
| 2020 |
Kovermann P, Untiet V, Kolobkova Y, Engels M, Baader S, Schilling K, Fahlke C. Increased glutamate transporter-associated anion currents cause glial apoptosis in episodic ataxia 6. Brain Communications. 2: fcaa022. PMID 32954283 DOI: 10.1093/braincomms/fcaa022 |
0.522 |
|
| 2020 |
Kolen B, Kortzak D, Franzen A, Fahlke C. An amino-terminal point mutation increases EAAT2 anion currents without affecting glutamate transport rates. The Journal of Biological Chemistry. PMID 32820048 DOI: 10.1074/Jbc.Ra120.013704 |
0.637 |
|
| 2020 |
Chivukula AS, Suslova M, Kortzak D, Kovermann P, Fahlke C. Functional consequences of SLC1A3 mutations associated with episodic ataxia 6. Human Mutation. PMID 32741053 DOI: 10.1002/Humu.24089 |
0.458 |
|
| 2020 |
Grieschat M, Guzman RE, Langschwager K, Fahlke C, Alekov AK. Metabolic energy sensing by mammalian CLC anion/proton exchangers. Embo Reports. e47872. PMID 32390228 DOI: 10.15252/Embr.201947872 |
0.467 |
|
| 2020 |
Chiariello MG, Bolnykh V, Ippoliti E, Meloni S, Olsen JMH, Beck T, Rothlisberger U, Fahlke C, Carloni P. Molecular Basis of CLC Antiporter Inhibition by Fluoride. Journal of the American Chemical Society. PMID 32233472 DOI: 10.1021/Jacs.9B13588 |
0.449 |
|
| 2019 |
Schewe J, Seidel E, Forslund S, Marko L, Peters J, Muller DN, Fahlke C, Stölting G, Scholl U. Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation. Nature Communications. 10: 5155. PMID 31727896 DOI: 10.1038/S41467-019-13033-4 |
0.304 |
|
| 2019 |
Bratanov D, Kovalev K, Machtens JP, Astashkin R, Chizhov I, Soloviov D, Volkov D, Polovinkin V, Zabelskii D, Mager T, Gushchin I, Rokitskaya T, Antonenko Y, Alekseev A, Shevchenko V, ... ... Fahlke C, et al. Unique structure and function of viral rhodopsins. Nature Communications. 10: 4939. PMID 31666521 DOI: 10.1038/S41467-019-12718-0 |
0.739 |
|
| 2019 |
Meyer J, Untiet V, Fahlke C, Gensch T, Rose CR. Quantitative determination of cellular [Na] by fluorescence lifetime imaging with CoroNaGreen. The Journal of General Physiology. PMID 31597684 DOI: 10.1085/Jgp.201912404 |
0.345 |
|
| 2019 |
Kortzak D, Alleva C, Weyand I, Ewers D, Zimmermann MI, Franzen A, Machtens JP, Fahlke C. Allosteric gate modulation confers K coupling in glutamate transporters. The Embo Journal. e101468. PMID 31506973 DOI: 10.15252/Embj.2019101468 |
0.793 |
|
| 2019 |
Viennet T, Bungert-Plümke S, Elter S, Viegas A, Fahlke C, Etzkorn M. Reconstitution and NMR Characterization of the Ion-Channel Accessory Subunit Barttin in Detergents and Lipid-Bilayer Nanodiscs. Frontiers in Molecular Biosciences. 6: 13. PMID 30931313 DOI: 10.3389/Fmolb.2019.00013 |
0.434 |
|
| 2018 |
Wojciechowski D, Kovalchuk E, Yu L, Tan H, Fahlke C, Stölting G, Alekov AK. Barttin Regulates the Subcellular Localization and Posttranslational Modification of Human Cl/H Antiporter ClC-5. Frontiers in Physiology. 9: 1490. PMID 30405442 DOI: 10.3389/Fphys.2018.01490 |
0.425 |
|
| 2018 |
Guzman RE, Fahlke C. ClC-3: biophysical properties clarify cellular functions. The Journal of Physiology. PMID 29974478 DOI: 10.1113/Jp276670 |
0.385 |
|
| 2018 |
Scholl UI, Stölting G, Schewe J, Thiel A, Tan H, Nelson-Williams C, Vichot AA, Jin SC, Loring E, Untiet V, Yoo T, Choi J, Xu S, Wu A, Kirchner M, ... ... Fahlke C, et al. CLCN2 chloride channel mutations in familial hyperaldosteronism type II. Nature Genetics. PMID 29403011 DOI: 10.1038/S41588-018-0048-5 |
0.429 |
|
| 2017 |
Martineau M, Guzman RE, Fahlke C, Klingauf J. VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses. Nature Communications. 8: 2279. PMID 29273736 DOI: 10.1038/S41467-017-02367-6 |
0.554 |
|
| 2017 |
Kovermann P, Hessel M, Kortzak D, Jen JC, Koch J, Fahlke C, Freilinger T. Impaired K(+) binding to glial glutamate transporter EAAT1 in migraine. Scientific Reports. 7: 13913. PMID 29066757 DOI: 10.1038/S41598-017-14176-4 |
0.536 |
|
| 2017 |
Guzman RE, Bungert-Plümke S, Franzen A, Fahlke C. Preferential Association with ClC-3 Permits Sorting of ClC-4 into Endosomal Compartments. The Journal of Biological Chemistry. PMID 28972156 DOI: 10.1074/Jbc.M117.801951 |
0.37 |
|
| 2017 |
Tan H, Bungert-Plümke S, Fahlke C, Stölting G. Reduced Membrane Insertion of CLC-K by V33L Barttin Results in Loss of Hearing, but Leaves Kidney Function Intact. Frontiers in Physiology. 8: 269. PMID 28555110 DOI: 10.3389/Fphys.2017.00269 |
0.426 |
|
| 2017 |
Machtens JP, Briones R, Alleva C, de Groot BL, Fahlke C. Gating Charge Calculations by Computational Electrophysiology Simulations. Biophysical Journal. 112: 1396-1405. PMID 28402882 DOI: 10.1016/J.Bpj.2017.02.016 |
0.801 |
|
| 2016 |
Rose CR, Ziemens D, Untiet V, Fahlke C. Molecular and cellular physiology of sodium-dependent glutamate transporters. Brain Research Bulletin. PMID 28040508 DOI: 10.1016/J.Brainresbull.2016.12.013 |
0.527 |
|
| 2016 |
Untiet V, Kovermann P, Gerkau NJ, Gensch T, Rose CR, Fahlke C. Glutamate transporter-associated anion channels adjust intracellular chloride concentrations during glial maturation. Glia. PMID 27859594 DOI: 10.1002/Glia.23098 |
0.573 |
|
| 2016 |
Stölting G, Fahlke C. Chloride channels in renal salt and water transport. Acta Physiologica (Oxford, England). PMID 27636562 DOI: 10.1111/Apha.12802 |
0.374 |
|
| 2016 |
Fahlke C, Nilius B. Molecular physiology of anion channels: dual function proteins and new structural motifs-a special issue. Pflugers Archiv : European Journal of Physiology. PMID 26769337 DOI: 10.1007/S00424-016-1791-Z |
0.403 |
|
| 2016 |
Schmalzing G, Detro-Dassen S, Fahlke C, Markwardt F. Oligomerization States of LRRC8A and LRRC8B, Essential Components of the Volume-Regulated Anion Channel VRAC Biophysical Journal. 110: 119a-120a. DOI: 10.1016/J.Bpj.2015.11.695 |
0.321 |
|
| 2016 |
Machtens J, Briones R, de Groot BL, Fahlke C. Gating Charge Calculations: Probing Voltage-Sensing Proteins through Computational Electrophysiology Biophysical Journal. 110: 106a. DOI: 10.1016/J.Bpj.2015.11.628 |
0.395 |
|
| 2015 |
Fahlke C, Kortzak D, Machtens JP. Molecular physiology of EAAT anion channels. Pflugers Archiv : European Journal of Physiology. PMID 26687113 DOI: 10.1007/S00424-015-1768-3 |
0.826 |
|
| 2015 |
Ronstedt K, Sternberg D, Detro-Dassen S, Gramkow T, Begemann B, Becher T, Kilian P, Grieschat M, Machtens JP, Schmalzing G, Fischer M, Fahlke C. Impaired surface membrane insertion of homo- and heterodimeric human muscle chloride channels carrying amino-terminal myotonia-causing mutations. Scientific Reports. 5: 15382. PMID 26502825 DOI: 10.1038/Srep15382 |
0.774 |
|
| 2015 |
Silverstein N, Ewers D, Forrest LR, Fahlke C, Kanner BI. Molecular Determinants of Substrate Specificity in Sodium-Coupled Glutamate Transporters. The Journal of Biological Chemistry. PMID 26475859 DOI: 10.1074/Jbc.M115.682666 |
0.534 |
|
| 2015 |
Stölting G, Bungert-Plümke S, Franzen A, Fahlke C. Carboxy-terminal Truncations of ClC-Kb Abolish Channel Activation by Barttin Via Modified Common Gating and Trafficking. The Journal of Biological Chemistry. PMID 26453302 DOI: 10.1074/Jbc.M115.675827 |
0.477 |
|
| 2015 |
Guzman RE, Miranda-Laferte E, Franzen A, Fahlke C. Neuronal ClC-3 Splice Variants Differ in Subcellular Localizations, but Mediate Identical Transport Functions. The Journal of Biological Chemistry. 290: 25851-62. PMID 26342074 DOI: 10.1074/Jbc.M115.668186 |
0.411 |
|
| 2015 |
Wojciechowski D, Fischer M, Fahlke C. Tryptophan Scanning Mutagenesis Identifies the Molecular Determinants of Distinct Barttin Functions. The Journal of Biological Chemistry. 290: 18732-43. PMID 26063802 DOI: 10.1074/Jbc.M114.625376 |
0.452 |
|
| 2015 |
Steinke KV, Gorinski N, Wojciechowski D, Todorov V, Guseva D, Ponimaskin E, Fahlke C, Fischer M. Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional. The Journal of Biological Chemistry. 290: 17390-400. PMID 26013830 DOI: 10.1074/Jbc.M114.631705 |
0.456 |
|
| 2015 |
Scholl UI, Stölting G, Nelson-Williams C, Vichot AA, Choi M, Loring E, Prasad ML, Goh G, Carling T, Juhlin CC, Quack I, Rump LC, Thiel A, Lande M, Frazier BG, ... ... Fahlke C, et al. Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism. Elife. 4: e06315. PMID 25907736 DOI: 10.7554/Elife.06315 |
0.365 |
|
| 2015 |
Machtens JP, Kortzak D, Lansche C, Leinenweber A, Kilian P, Begemann B, Zachariae U, Ewers D, de Groot BL, Briones R, Fahlke C. Mechanisms of anion conduction by coupled glutamate transporters. Cell. 160: 542-53. PMID 25635461 DOI: 10.1016/J.Cell.2014.12.035 |
0.853 |
|
| 2015 |
Jensen AA, Fahlke C, Bjørn-Yoshimoto WE, Bunch L. Excitatory amino acid transporters: recent insights into molecular mechanisms, novel modes of modulation and new therapeutic possibilities. Current Opinion in Pharmacology. 20: 116-23. PMID 25466154 DOI: 10.1016/J.Coph.2014.10.008 |
0.49 |
|
| 2015 |
Scholl UI, Stölting G, Nelson-Williams C, Vichot AA, Choi M, Loring E, Prasad ML, Goh G, Carling T, Juhlin CC, Quack I, Rump LC, Thiel A, Lande M, Frazier BG, ... ... Fahlke C, et al. Author response: Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism Elife. DOI: 10.7554/Elife.06315.019 |
0.341 |
|
| 2015 |
Machtens J, Grieschat M, Fahlke C, Alekov AK. Molecular Basis of Voltage-Dependent Gating in ClC Transporters Biophysical Journal. 108: 428a. DOI: 10.1016/J.Bpj.2014.11.2340 |
0.495 |
|
| 2014 |
Stölting G, Fischer M, Fahlke C. CLC channel function and dysfunction in health and disease. Frontiers in Physiology. 5: 378. PMID 25339907 DOI: 10.3389/Fphys.2014.00378 |
0.519 |
|
| 2014 |
Fahlke C. Behind the scenes of CLC gating: deriving the voltage dependence of membrane proteins by admittance measurements. Biophysical Journal. 107: 1261-2. PMID 25229133 DOI: 10.1016/J.Bpj.2014.08.002 |
0.579 |
|
| 2014 |
Guzman RE, Alekov AK, Filippov M, Hegermann J, Fahlke C. Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons. Frontiers in Cellular Neuroscience. 8: 143. PMID 24904288 DOI: 10.3389/Fncel.2014.00143 |
0.389 |
|
| 2014 |
Stölting G, Fischer M, Fahlke C. ClC-1 and ClC-2 form hetero-dimeric channels with novel protopore functions. PflüGers Archiv : European Journal of Physiology. 466: 2191-204. PMID 24638271 DOI: 10.1007/S00424-014-1490-6 |
0.478 |
|
| 2014 |
Kegler K, Imbschweiler I, Ulrich R, Kovermann P, Fahlke C, Deschl U, Kalkuhl A, Baumgärnter W, Wewetzer K. CNS Schwann cells display oligodendrocyte precursor-like potassium channel activation and antigenic expression in vitro. Journal of Neural Transmission (Vienna, Austria : 1996). 121: 569-81. PMID 24487976 DOI: 10.1007/S00702-014-1163-9 |
0.381 |
|
| 2014 |
Schneider N, Cordeiro S, Machtens JP, Braams S, Rauen T, Fahlke C. Functional properties of the retinal glutamate transporters GLT-1c and EAAT5. The Journal of Biological Chemistry. 289: 1815-24. PMID 24307171 DOI: 10.1074/Jbc.M113.517177 |
0.831 |
|
| 2014 |
Machtens J, Lansche C, Leinenweber A, Kilian P, Begemann B, Zachariae U, Ewers D, de Groot BL, Briones R, Fahlke C. Anion Permeation through Excitatory Amino Acid Transporters Biophysical Journal. 106: 149a. DOI: 10.1016/J.Bpj.2013.11.858 |
0.633 |
|
| 2014 |
Guzman Castro RE, Miranda Laferte E, Stölting G, Fahlke C. The Amino Terminus Controls Sorting and Voltage Dependence of CLC 3 Biophysical Journal. 106: 146a. DOI: 10.1016/J.Bpj.2013.11.845 |
0.42 |
|
| 2013 |
Hotzy J, Schneider N, Kovermann P, Fahlke C. Mutating a conserved proline residue within the trimerization domain modifies Na+ binding to excitatory amino acid transporters and associated conformational changes. The Journal of Biological Chemistry. 288: 36492-501. PMID 24214974 DOI: 10.1074/Jbc.M113.489385 |
0.593 |
|
| 2013 |
Scholl UI, Goh G, Stölting G, de Oliveira RC, Choi M, Overton JD, Fonseca AL, Korah R, Starker LF, Kunstman JW, Prasad ML, Hartung EA, Mauras N, Benson MR, Brady T, ... ... Fahlke C, et al. Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. Nature Genetics. 45: 1050-4. PMID 23913001 DOI: 10.1038/Ng.2695 |
0.42 |
|
| 2013 |
Ewers D, Becher T, Machtens JP, Weyand I, Fahlke C. Induced fit substrate binding to an archeal glutamate transporter homologue. Proceedings of the National Academy of Sciences of the United States of America. 110: 12486-91. PMID 23840066 DOI: 10.1073/Pnas.1300772110 |
0.77 |
|
| 2013 |
Stölting G, Teodorescu G, Begemann B, Schubert J, Nabbout R, Toliat MR, Sander T, Nürnberg P, Lerche H, Fahlke C. Regulation of ClC-2 gating by intracellular ATP. Pflã¼Gers Archiv : European Journal of Physiology. 465: 1423-37. PMID 23632988 DOI: 10.1007/S00424-013-1286-0 |
0.47 |
|
| 2013 |
Guzman RE, Grieschat M, Fahlke C, Alekov AK. ClC-3 is an intracellular chloride/proton exchanger with large voltage-dependent nonlinear capacitance. Acs Chemical Neuroscience. 4: 994-1003. PMID 23509947 DOI: 10.1021/Cn400032Z |
0.484 |
|
| 2013 |
Abrahamsen B, Schneider N, Erichsen MN, Huynh TH, Fahlke C, Bunch L, Jensen AA. Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1068-87. PMID 23325245 DOI: 10.1523/Jneurosci.3396-12.2013 |
0.477 |
|
| 2012 |
Winter N, Kovermann P, Fahlke C. A point mutation associated with episodic ataxia 6 increases glutamate transporter anion currents. Brain : a Journal of Neurology. 135: 3416-25. PMID 23107647 DOI: 10.1093/Brain/Aws255 |
0.577 |
|
| 2012 |
Weinberger S, Wojciechowski D, Sternberg D, Lehmann-Horn F, Jurkat-Rott K, Becher T, Begemann B, Fahlke C, Fischer M. Disease-causing mutations C277R and C277Y modify gating of human ClC-1 chloride channels in myotonia congenita. The Journal of Physiology. 590: 3449-64. PMID 22641783 DOI: 10.1113/Jphysiol.2012.232785 |
0.462 |
|
| 2012 |
Hotzy J, Machtens JP, Fahlke C. Neutralizing aspartate 83 modifies substrate translocation of excitatory amino acid transporter 3 (EAAT3) glutamate transporters. The Journal of Biological Chemistry. 287: 20016-26. PMID 22532568 DOI: 10.1074/Jbc.M112.344077 |
0.837 |
|
| 2012 |
Schänzler M, Fahlke C. Anion transport by the cochlear motor protein prestin. The Journal of Physiology. 590: 259-72. PMID 22063625 DOI: 10.1113/Jphysiol.2011.209577 |
0.526 |
|
| 2012 |
Grieschat M, Fahlke C, Alekov AK. Lysine 210 Regulates Voltage-Dependent Gating of the Anion-Proton Exchanger CLC-5 Biophysical Journal. 102: 521a. DOI: 10.1016/J.Bpj.2011.11.2848 |
0.482 |
|
| 2012 |
Fahlke C. Glutamate Transporter-Associated Anion Channels Biophysical Journal. 102: 407a. DOI: 10.1016/J.Bpj.2011.11.2227 |
0.603 |
|
| 2011 |
Machtens JP, Fahlke C, Kovermann P. Noise analysis to study unitary properties of transporter-associated ion channels. Channels (Austin, Tex.). 5: 468-74. PMID 21849820 DOI: 10.4161/Chan.5.6.17453 |
0.812 |
|
| 2011 |
Machtens JP, Kovermann P, Fahlke C. Substrate-dependent gating of anion channels associated with excitatory amino acid transporter 4. The Journal of Biological Chemistry. 286: 23780-8. PMID 21572047 DOI: 10.1074/Jbc.M110.207514 |
0.828 |
|
| 2011 |
Orhan G, Fahlke C, Alekov AK. Anion- and proton-dependent gating of ClC-4 anion/proton transporter under uncoupling conditions. Biophysical Journal. 100: 1233-41. PMID 21354396 DOI: 10.1016/J.Bpj.2011.01.045 |
0.555 |
|
| 2011 |
Fahlke C. Chloride channels take center stage in a muscular drama. The Journal of General Physiology. 137: 17-9. PMID 21149545 DOI: 10.1085/Jgp.201010574 |
0.396 |
|
| 2011 |
Nothmann D, Leinenweber A, Torres-Salazar D, Kovermann P, Hotzy J, Gameiro A, Grewer C, Fahlke C. Hetero-oligomerization of neuronal glutamate transporters. The Journal of Biological Chemistry. 286: 3935-43. PMID 21127051 DOI: 10.1074/Jbc.M110.187492 |
0.814 |
|
| 2011 |
Leinenweber A, Machtens JP, Begemann B, Fahlke C. Regulation of glial glutamate transporters by C-terminal domains. The Journal of Biological Chemistry. 286: 1927-37. PMID 21097502 DOI: 10.1074/Jbc.M110.153486 |
0.813 |
|
| 2011 |
Melzer N, Meuth SG, Torres-Salazar D, Bittner S, Zozulya AL, Weidenfeller C, Kotsiari A, Stangel M, Fahlke C, Wiendl H. Correction: A β-Lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis Plos One. 6. DOI: 10.1371/annotation/b1ff1c14-fa84-40a0-b095-e5ee47c74125 |
0.741 |
|
| 2010 |
Fahlke C, Fischer M. Physiology and pathophysiology of ClC-K/barttin channels. Frontiers in Physiology. 1: 155. PMID 21423394 DOI: 10.3389/Fphys.2010.00155 |
0.465 |
|
| 2010 |
Fischer M, Janssen AG, Fahlke C. Barttin activates ClC-K channel function by modulating gating. Journal of the American Society of Nephrology : Jasn. 21: 1281-9. PMID 20538786 DOI: 10.1681/Asn.2009121274 |
0.466 |
|
| 2010 |
Kovermann P, Machtens JP, Ewers D, Fahlke C. A conserved aspartate determines pore properties of anion channels associated with excitatory amino acid transporter 4 (EAAT4). The Journal of Biological Chemistry. 285: 23676-86. PMID 20519505 DOI: 10.1074/Jbc.M110.126557 |
0.836 |
|
| 2010 |
Ewers D, Becher T, Krefft R, Hidalgo P, Fahlke C. Characterization of Substrate Binding by the Bacterial Aspartate Transporter GltPh Through Equilibrium and Stopped-Flow Tryptophan Fluorescence Measurements Biophysical Journal. 98: 686a. DOI: 10.1016/J.Bpj.2009.12.3766 |
0.442 |
|
| 2010 |
Grieschat M, Fahlke C, Alekov AK. Regulation of the Chloride/Proton Exchanger CLC-5 By Internal pH Biophysical Journal. 98: 319a. DOI: 10.1016/J.Bpj.2009.12.1734 |
0.459 |
|
| 2009 |
Haug K, Warnstedt M, Alekov AK, Sander T, Ramírez A, Poser B, Maljevic S, Hebeisen S, Kubisch C, Rebstock J, Horvath S, Hallmann K, Dullinger JS, Rau B, Haverkamp F, ... ... Fahlke C, et al. Retraction: Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies. Nature Genetics. 41: 1043. PMID 19710717 DOI: 10.1038/Ng0909-1043 |
0.399 |
|
| 2009 |
Riazuddin S, Anwar S, Fischer M, Ahmed ZM, Khan SY, Janssen AG, Zafar AU, Scholl U, Husnain T, Belyantseva IA, Friedman PL, Riazuddin S, Friedman TB, Fahlke C. Molecular basis of DFNB73: mutations of BSND can cause nonsyndromic deafness or Bartter syndrome. American Journal of Human Genetics. 85: 273-80. PMID 19646679 DOI: 10.1016/J.Ajhg.2009.07.003 |
0.339 |
|
| 2009 |
Alekov AK, Fahlke C. Channel-like slippage modes in the human anion/proton exchanger ClC-4. The Journal of General Physiology. 133: 485-96. PMID 19364886 DOI: 10.1085/Jgp.200810155 |
0.48 |
|
| 2009 |
Saint-Martin C, Gauvain G, Teodorescu G, Gourfinkel-An I, Fedirko E, Weber YG, Maljevic S, Ernst JP, Garcia-Olivares J, Fahlke C, Nabbout R, LeGuern E, Lerche H, Poncer JC, Depienne C. Two novel CLCN2 mutations accelerating chloride channel deactivation are associated with idiopathic generalized epilepsy. Human Mutation. 30: 397-405. PMID 19191339 DOI: 10.1002/Humu.20876 |
0.755 |
|
| 2009 |
Janssen AG, Scholl U, Domeyer C, Nothmann D, Leinenweber A, Fahlke C. Disease-causing dysfunctions of barttin in Bartter syndrome type IV. Journal of the American Society of Nephrology : Jasn. 20: 145-53. PMID 18776122 DOI: 10.1681/Asn.2008010102 |
0.439 |
|
| 2009 |
Kovermann PA, Fahlke C. Voltage-dependent Gating Of Wt And D177a Eaat4-associated Anion Channels Biophysical Journal. 96: 472a. DOI: 10.1016/J.Bpj.2008.12.2429 |
0.598 |
|
| 2008 |
Alekov AK, Fahlke C. Anion channels: regulation of ClC-3 by an orphan second messenger. Current Biology : Cb. 18: R1061-4. PMID 19036336 DOI: 10.1016/J.Cub.2008.09.023 |
0.492 |
|
| 2008 |
Garcia-Olivares J, Alekov A, Boroumand MR, Begemann B, Hidalgo P, Fahlke C. Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains. The Journal of Physiology. 586: 5325-36. PMID 18801843 DOI: 10.1113/Jphysiol.2008.158097 |
0.795 |
|
| 2008 |
Melzer N, Meuth SG, Torres-Salazar D, Bittner S, Zozulya AL, Weidenfeller C, Kotsiari A, Stangel M, Fahlke C, Wiendl H. A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis. Plos One. 3: e3149. PMID 18773080 DOI: 10.1371/Journal.Pone.0003149 |
0.801 |
|
| 2008 |
Detro-Dassen S, Schänzler M, Lauks H, Martin I, zu Berstenhorst SM, Nothmann D, Torres-Salazar D, Hidalgo P, Schmalzing G, Fahlke C. Conserved dimeric subunit stoichiometry of SLC26 multifunctional anion exchangers. The Journal of Biological Chemistry. 283: 4177-88. PMID 18073211 DOI: 10.1074/Jbc.M704924200 |
0.776 |
|
| 2008 |
Melzer N, Meuth SG, Torres-Salazar D, Bittner S, Zozulya AL, Weidenfeller C, Kotsiari A, Stangel M, Fahlke C, Wiendl H. Correction: A β-Lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis Plos One. 3. DOI: 10.1371/annotation/b898d6ee-801a-474e-9776-72e4da664b89 |
0.741 |
|
| 2007 |
Torres-Salazar D, Fahlke C. Neuronal glutamate transporters vary in substrate transport rate but not in unitary anion channel conductance. The Journal of Biological Chemistry. 282: 34719-26. PMID 17908688 DOI: 10.1074/Jbc.M704118200 |
0.838 |
|
| 2007 |
Torres-Salazar D, Fahlke C. Parawixin1: a spider toxin opening new avenues for glutamate transporter pharmacology. Molecular Pharmacology. 72: 1100-2. PMID 17726155 DOI: 10.1124/Mol.107.041020 |
0.801 |
|
| 2006 |
Scholl U, Hebeisen S, Janssen AG, Müller-Newen G, Alekov A, Fahlke C. Barttin modulates trafficking and function of ClC-K channels. Proceedings of the National Academy of Sciences of the United States of America. 103: 11411-6. PMID 16849430 DOI: 10.1073/Pnas.0601631103 |
0.453 |
|
| 2006 |
Torres-Salazar D, Fahlke C. Intersubunit interactions in EAAT4 glutamate transporters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7513-22. PMID 16837599 DOI: 10.1523/Jneurosci.4545-05.2006 |
0.833 |
|
| 2005 |
Melzer N, Torres-Salazar D, Fahlke C. A dynamic switch between inhibitory and excitatory currents in a neuronal glutamate transporter. Proceedings of the National Academy of Sciences of the United States of America. 102: 19214-8. PMID 16365297 DOI: 10.1073/Pnas.0508837103 |
0.855 |
|
| 2005 |
Hebeisen S, Fahlke C. Carboxy-terminal truncations modify the outer pore vestibule of muscle chloride channels. Biophysical Journal. 89: 1710-20. PMID 15980168 DOI: 10.1529/Biophysj.104.056093 |
0.472 |
|
| 2005 |
Shcherbyna I, Hidalgo P, Fahlke C. Functional characterization of bacterial glutamate transporter reconstituted in lipide membranes Ukrain'Skyi Biokhimichnyi Zhurnal. 77: 75. |
0.338 |
|
| 2004 |
Gendreau S, Voswinkel S, Torres-Salazar D, Lang N, Heidtmann H, Detro-Dassen S, Schmalzing G, Hidalgo P, Fahlke C. A trimeric quaternary structure is conserved in bacterial and human glutamate transporters. The Journal of Biological Chemistry. 279: 39505-12. PMID 15265858 DOI: 10.1074/Jbc.M408038200 |
0.813 |
|
| 2004 |
Hebeisen S, Biela A, Giese B, Müller-Newen G, Hidalgo P, Fahlke C. The role of the carboxyl terminus in ClC chloride channel function. The Journal of Biological Chemistry. 279: 13140-7. PMID 14718533 DOI: 10.1074/Jbc.M312649200 |
0.469 |
|
| 2004 |
Fahlke C. Molecular physiology and pathophysiology of ClC-type chloride channels Advances in Molecular and Cell Biology. 32: 189-217. DOI: 10.1016/S1569-2558(03)32009-0 |
0.438 |
|
| 2003 |
Melzer N, Biela A, Fahlke C. Glutamate modifies ion conduction and voltage-dependent gating of excitatory amino acid transporter-associated anion channels. The Journal of Biological Chemistry. 278: 50112-9. PMID 14506254 DOI: 10.1074/Jbc.M307990200 |
0.76 |
|
| 2003 |
Hebeisen S, Heidtmann H, Cosmelli D, Gonzalez C, Poser B, Latorre R, Alvarez O, Fahlke C. Anion permeation in human ClC-4 channels. Biophysical Journal. 84: 2306-18. PMID 12668439 DOI: 10.1016/S0006-3495(03)75036-X |
0.476 |
|
| 2002 |
Ryan A, Rüdel R, Kuchenbecker M, Fahlke C. A novel alteration of muscle chloride channel gating in myotonia levior. The Journal of Physiology. 545: 345-54. PMID 12456816 DOI: 10.1113/Jphysiol.2002.027037 |
0.485 |
|
| 2002 |
Wu FF, Ryan A, Devaney J, Warnstedt M, Korade-Mirnics Z, Poser B, Escriva MJ, Pegoraro E, Yee AS, Felice KJ, Giuliani MJ, Mayer RF, Mongini T, Palmucci L, Marino M, ... ... Fahlke C, et al. Novel CLCN1 mutations with unique clinical and electrophysiological consequences. Brain : a Journal of Neurology. 125: 2392-407. PMID 12390967 DOI: 10.1093/Brain/Awf246 |
0.391 |
|
| 2002 |
Warnstedt M, Sun C, Poser B, Escriva MJ, Tranebjaerg L, Torbergsen T, van Ghelue M, Fahlke C. The myotonia congenita mutation A331T confers a novel hyperpolarization-activated gate to the muscle chloride channel ClC-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7462-70. PMID 12196568 DOI: 10.1523/Jneurosci.22-17-07462.2002 |
0.447 |
|
| 2001 |
Fahlke C. Ion permeation and selectivity in ClC-type chloride channels. American Journal of Physiology. Renal Physiology. 280: F748-57. PMID 11292616 DOI: 10.1152/Ajprenal.2001.280.5.F748 |
0.447 |
|
| 2001 |
Fahlke C, Desai RR, Gillani N, George AL. Residues lining the inner pore vestibule of human muscle chloride channels. The Journal of Biological Chemistry. 276: 1759-65. PMID 11035024 DOI: 10.1074/Jbc.M007649200 |
0.442 |
|
| 2000 |
Fahlke C. Molecular mechanisms of ion conduction in ClC-type chloride channels: lessons from disease-causing mutations. Kidney International. 57: 780-6. PMID 10720929 DOI: 10.1046/J.1523-1755.2000.00915.X |
0.46 |
|
| 1999 |
Rhodes TH, Vite CH, Giger U, Patterson DF, Fahlke C, George AL. A missense mutation in canine C1C-1 causes recessive myotonia congenita in the dog. Febs Letters. 456: 54-8. PMID 10452529 DOI: 10.1016/S0014-5793(99)00926-6 |
0.386 |
|
| 1999 |
Rosenbohm A, Rüdel R, Fahlke C. Regulation of the human skeletal muscle chloride channel hClC-1 by protein kinase C. The Journal of Physiology. 514: 677-85. PMID 9882739 DOI: 10.1111/J.1469-7793.1999.677Ad.X |
0.355 |
|
| 1998 |
Fahlke C, Rhodes TH, Desai RR, George AL. Pore stoichiometry of a voltage-gated chloride channel. Nature. 394: 687-90. PMID 9716133 DOI: 10.1038/29319 |
0.476 |
|
| 1997 |
Fahlke C, Yu HT, Beck CL, Rhodes TH, George AL. Pore-forming segments in voltage-gated chloride channels. Nature. 390: 529-32. PMID 9394005 DOI: 10.1038/37391 |
0.44 |
|
| 1997 |
Fahlke C, Dürr C, George AL. Mechanism of ion permeation in skeletal muscle chloride channels. The Journal of General Physiology. 110: 551-64. PMID 9348327 DOI: 10.1085/Jgp.110.5.551 |
0.475 |
|
| 1997 |
Fahlke C, Beck CL, George AL. A mutation in autosomal dominant myotonia congenita affects pore properties of the muscle chloride channel. Proceedings of the National Academy of Sciences of the United States of America. 94: 2729-34. PMID 9122265 DOI: 10.1073/Pnas.94.6.2729 |
0.488 |
|
| 1997 |
Fahlke C, Knittle T, Gurnett CA, Campbell KP, George AL. Subunit stoichiometry of human muscle chloride channels. The Journal of General Physiology. 109: 93-104. PMID 8997668 DOI: 10.1085/Jgp.109.1.93 |
0.475 |
|
| 1996 |
Beck CL, Fahlke C, George AL. Molecular basis for decreased muscle chloride conductance in the myotonic goat. Proceedings of the National Academy of Sciences of the United States of America. 93: 11248-52. PMID 8855341 DOI: 10.1073/Pnas.93.20.11248 |
0.348 |
|
| 1996 |
Fahlke C, Rosenbohm A, Mitrovic N, George AL, Rüdel R. Mechanism of voltage-dependent gating in skeletal muscle chloride channels. Biophysical Journal. 71: 695-706. PMID 8842208 DOI: 10.1016/S0006-3495(96)79269-X |
0.455 |
|
| 1995 |
Fahlke C, Rüdel R, Mitrovic N, Zhou M, George AL. An aspartic acid residue important for voltage-dependent gating of human muscle chloride channels. Neuron. 15: 463-72. PMID 7646898 DOI: 10.1016/0896-6273(95)90050-0 |
0.493 |
|
| 1995 |
Fahlke C, Rüdel R. Chloride currents across the membrane of mammalian skeletal muscle fibres. The Journal of Physiology. 484: 355-68. PMID 7602531 DOI: 10.1113/Jphysiol.1995.Sp020670 |
0.347 |
|
| 1995 |
Mitrović N, George AL, Lerche H, Wagner S, Fahlke C, Lehmann-Horn F. Different effects on gating of three myotonia-causing mutations in the inactivation gate of the human muscle sodium channel. The Journal of Physiology. 487: 107-14. PMID 7473241 DOI: 10.1113/Jphysiol.1995.Sp020864 |
0.454 |
|
| 1994 |
Mitrović N, George AL, Heine R, Wagner S, Pika U, Hartlaub U, Zhou M, Lerche H, Fahlke C, Lehmann-Horn F. K(+)-aggravated myotonia: destabilization of the inactivated state of the human muscle Na+ channel by the V1589M mutation. The Journal of Physiology. 478: 395-402. PMID 7965854 DOI: 10.1113/Jphysiol.1994.Sp020260 |
0.469 |
|
| 1994 |
Häussler U, Rivet-Bastide M, Fahlke C, Müller D, Zachar E, Rüdel R. Role of the cytoskeleton in the regulation of Cl- channels in human embryonic skeletal muscle cells. Pflã¼Gers Archiv : European Journal of Physiology. 428: 323-30. PMID 7816555 DOI: 10.1007/BF00724514 |
0.325 |
|
| 1993 |
Fahlke C, Zachar E, Rüdel R. Chloride channels with reduced single-channel conductance in recessive myotonia congenita. Neuron. 10: 225-32. PMID 8382498 DOI: 10.1016/0896-6273(93)90313-G |
0.368 |
|
| 1992 |
Fahlke C, Zachar E, Rüdel R. Single-channel recordings of chloride currents in cultured human skeletal muscle. Pflã¼Gers Archiv : European Journal of Physiology. 421: 108-16. PMID 1382261 DOI: 10.1007/BF00374816 |
0.367 |
|
| 1992 |
Fahlke C, Rüdel R. Giga-seal formation alters properties of sodium channels of human myoballs. Pflã¼Gers Archiv : European Journal of Physiology. 420: 248-54. PMID 1317948 DOI: 10.1007/BF00374454 |
0.314 |
|
| 1992 |
Fahlke C, Zachar E, Häussler U, Rüdel R. Chloride channels in cultured human skeletal muscle are regulated by G proteins. Pflã¼Gers Archiv : European Journal of Physiology. 421: 566-71. PMID 1279515 DOI: 10.1007/BF00375052 |
0.315 |
|
| 1988 |
Fahlke C, Ruppersberg JP. Saturation effects and rectifier properties of sodium channels in human skeletal muscle. European Biophysics Journal : Ebj. 16: 307-12. PMID 2853670 DOI: 10.1007/Bf00254067 |
0.432 |
|
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