| Year |
Citation |
Score |
| 2017 |
Lis P, Burel S, Steger M, Mann M, Brown F, Diez F, Tonelli F, Holton JL, Ho PW, Ho SL, Chou MY, Polinski NK, Martinez TN, Davies P, Alessi DR. Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase. The Biochemical Journal. PMID 29127256 DOI: 10.1042/Bcj20170802 |
0.327 |
|
| 2016 |
Steger M, Tonelli F, Ito G, Davies P, Trost M, Vetter M, Wachter S, Lorentzen E, Duddy G, Wilson S, Baptista MA, Fiske BK, Fell MJ, Morrow JA, Reith AD, et al. Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases. Elife. 5. PMID 26824392 DOI: 10.7554/Elife.12813 |
0.308 |
|
| 2015 |
Bago R, Sommer E, Malik N, Munson MJ, Prescott AR, Davies P, Natalia S, Ganley IG, Alessi DR. Abstract A04: Characterization of VPS34-IN1, a specific inhibitor of Vps34 reveals that the phosphatidylinositol 3-phosphate binding SGK3 protein kinase is regulated by class III PI-3 kinase Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-A04 |
0.32 |
|
| 2014 |
Bago R, Malik N, Munson MJ, Prescott AR, Davies P, Sommer E, Shpiro N, Ward R, Cross D, Ganley IG, Alessi DR. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase. The Biochemical Journal. 463: 413-27. PMID 25177796 DOI: 10.1042/Bj20140889 |
0.307 |
|
| 2014 |
Houde VP, Ritorto MS, Gourlay R, Varghese J, Davies P, Shpiro N, Sakamoto K, Alessi DR. Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity. The Biochemical Journal. 458: 41-56. PMID 24295069 DOI: 10.1042/Bj20131324 |
0.301 |
|
| 2013 |
Younan ND, Sarell CJ, Davies P, Brown DR, Viles JH. The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1847-58. PMID 23335053 DOI: 10.1096/Fj.12-222588 |
0.446 |
|
| 2012 |
Younan ND, Nadal RC, Davies P, Brown DR, Viles JH. Methionine oxidation perturbs the structural core of the prion protein and suggests a generic misfolding pathway. The Journal of Biological Chemistry. 287: 28263-75. PMID 22654104 DOI: 10.1074/Jbc.M112.354779 |
0.43 |
|
| 2012 |
Meloni G, Crameri A, Fritz G, Davies P, Brown DR, Kroneck PM, Vašák M. The catalytic redox activity of prion protein-Cu(II) is controlled by metal exchange with the Zn(II) -thiolate clusters of Zn(7) metallothionein-3. Chembiochem : a European Journal of Chemical Biology. 13: 1261-5. PMID 22615124 DOI: 10.1002/Cbic.201200198 |
0.449 |
|
| 2011 |
Davies P, McHugh PC, Hammond VJ, Marken F, Brown DR. Contribution of individual histidines to prion protein copper binding. Biochemistry. 50: 10781-91. PMID 22039779 DOI: 10.1021/Bi2012349 |
0.503 |
|
| 2011 |
Younan ND, Klewpatinond M, Davies P, Ruban AV, Brown DR, Viles JH. Copper(II)-induced secondary structure changes and reduced folding stability of the prion protein. Journal of Molecular Biology. 410: 369-82. PMID 21619885 DOI: 10.1016/J.Jmb.2011.05.013 |
0.479 |
|
| 2011 |
Davies P, Moualla D, Brown DR. Alpha-synuclein is a cellular ferrireductase. Plos One. 6: e15814. PMID 21249223 DOI: 10.1371/Journal.Pone.0015814 |
0.433 |
|
| 2011 |
Davies P, Wang X, Sarell CJ, Drewett A, Marken F, Viles JH, Brown DR. The synucleins are a family of redox-active copper binding proteins. Biochemistry. 50: 37-47. PMID 21117662 DOI: 10.1021/Bi101582P |
0.562 |
|
| 2009 |
Davies P, Brown DR. Manganese enhances prion protein survival in model soils and increases prion infectivity to cells. Plos One. 4: e7518. PMID 19844576 DOI: 10.1371/Journal.Pone.0007518 |
0.409 |
|
| 2009 |
Nadal RC, Davies P, Brown DR, Viles JH. Evaluation of copper2+ affinities for the prion protein. Biochemistry. 48: 8929-31. PMID 19697960 DOI: 10.1021/Bi9011397 |
0.494 |
|
| 2009 |
Chang B, Gray P, Piltch M, Bulgin MS, Sorensen-Melson S, Miller MW, Davies P, Brown DR, Coughlin DR, Rubenstein R. Surround optical fiber immunoassay (SOFIA): an ultra-sensitive assay for prion protein detection. Journal of Virological Methods. 159: 15-22. PMID 19442839 DOI: 10.1016/J.Jviromet.2009.02.019 |
0.407 |
|
| 2009 |
Stevens DJ, Walter ED, RodrÃguez A, Draper D, Davies P, Brown DR, Millhauser GL. Early onset prion disease from octarepeat expansion correlates with copper binding properties. Plos Pathogens. 5: e1000390. PMID 19381258 DOI: 10.1371/Journal.Ppat.1000390 |
0.489 |
|
| 2009 |
Davies P, Marken F, Salter S, Brown DR. Thermodynamic and voltammetric characterization of the metal binding to the prion protein: insights into pH dependence and redox chemistry. Biochemistry. 48: 2610-9. PMID 19196019 DOI: 10.1021/Bi900170N |
0.512 |
|
| 2008 |
Davies P, Fontaine SN, Moualla D, Wang X, Wright JA, Brown DR. Amyloidogenic metal-binding proteins: new investigative pathways. Biochemical Society Transactions. 36: 1299-303. PMID 19021544 DOI: 10.1042/Bst0361299 |
0.691 |
|
| 2008 |
Brazier MW, Davies P, Player E, Marken F, Viles JH, Brown DR. Manganese binding to the prion protein. The Journal of Biological Chemistry. 283: 12831-9. PMID 18332141 DOI: 10.1074/Jbc.M709820200 |
0.62 |
|
| 2008 |
Davies P, Brown DR. The chemistry of copper binding to PrP: is there sufficient evidence to elucidate a role for copper in protein function? The Biochemical Journal. 410: 237-44. PMID 18254729 DOI: 10.1042/Bj20071477 |
0.502 |
|
| 2008 |
Zhu F, Davies P, Thompsett AR, Kelly SM, Tranter GE, Hecht L, Isaacs NW, Brown DR, Barron LD. Raman optical activity and circular dichroism reveal dramatic differences in the influence of divalent copper and manganese ions on prion protein folding. Biochemistry. 47: 2510-7. PMID 18205409 DOI: 10.1021/Bi7022893 |
0.467 |
|
| 2008 |
Klewpatinond M, Davies P, Bowen S, Brown DR, Viles JH. Deconvoluting the Cu2+ binding modes of full-length prion protein. The Journal of Biological Chemistry. 283: 1870-81. PMID 18042548 DOI: 10.1074/Jbc.M708472200 |
0.487 |
|
| 2007 |
Alderton A, Davies P, Illman K, Brown DR. Ancient conserved domain protein-1 binds copper and modifies its retention in cells. Journal of Neurochemistry. 103: 312-21. PMID 17608643 DOI: 10.1111/J.1471-4159.2007.04751.X |
0.495 |
|
| 2007 |
Butowt R, Davies P, Brown DR. Anterograde axonal transport of chicken cellular prion protein (PrPc) in vivo requires its N-terminal part. Journal of Neuroscience Research. 85: 2567-79. PMID 17335074 DOI: 10.1002/Jnr.21229 |
0.391 |
|
| 2006 |
de Silva R, Lashley T, Strand C, Shiarli AM, Shi J, Tian J, Bailey KL, Davies P, Bigio EH, Arima K, Iseki E, Murayama S, Kretzschmar H, Neumann M, Lippa C, et al. An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathologica. 111: 329-40. PMID 16552612 DOI: 10.1007/S00401-006-0048-X |
0.363 |
|
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