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Eileen H. Bigio, MD, University of Texas Medical Branch, MSc - Publications

Affiliations: 
Pathology Northwestern University, Evanston, IL 
Area:
Alzheimer's disease and related disorders
Website:
http://www.pathology.northwestern.edu/Faculty/FacultyBio.cfm?ID=2

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kawles A, Nishihira Y, Feldman A, Gill N, Minogue G, Keszycki R, Coventry C, Spencer C, Lilek J, Ajroud K, Coppola G, Rademakers R, Rogalski E, Weintraub S, Zhang H, ... ... Bigio EH, et al. Cortical and subcortical pathological burden and neuronal loss in an autopsy series of FTLD-TDP-type C. Brain : a Journal of Neurology. PMID 34919645 DOI: 10.1093/brain/awab368  0.484
2021 Iida MA, Farrell K, Walker JM, Richardson TE, Marx GA, Bryce CH, Purohit D, Ayalon G, Beach TG, Bigio EH, Cortes EP, Gearing M, Haroutunian V, McMillan CT, Lee EB, et al. Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study. Acta Neuropathologica Communications. 9: 134. PMID 34353357 DOI: 10.1186/s40478-021-01233-3  0.773
2021 Josephs KA, Duffy JR, Clark HM, Utianski RL, Strand EA, Machulda MM, Botha H, Martin PR, Pham NTT, Stierwalt J, Ali F, Buciuc M, Baker M, Fernandez De Castro CH, Spychalla AJ, ... ... Bigio EH, et al. A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech. Nature Communications. 12: 3452. PMID 34103532 DOI: 10.1038/s41467-021-23687-8  0.617
2021 Gefen T, Kawles A, Makowski-Woidan B, Engelmeyer J, Ayala I, Abbassian P, Zhang H, Weintraub S, Flanagan ME, Mao Q, Bigio EH, Rogalski E, Mesulam MM, Geula C. Paucity of Entorhinal Cortex Pathology of the Alzheimer's Type in SuperAgers with Superior Memory Performance. Cerebral Cortex (New York, N.Y. : 1991). PMID 33592091 DOI: 10.1093/cercor/bhaa409  0.535
2021 Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, ... ... Bigio EH, et al. Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nature Genetics. PMID 33589841 DOI: 10.1038/s41588-021-00785-3  0.476
2021 Mesulam MM, Coventry C, Kuang A, Bigio EH, Mao Q, Flanagan ME, Gefen T, Sridhar J, Geula C, Zhang H, Weintraub S, Rogalski EJ. Memory resilience in Alzheimer's disease with primary progressive aphasia. Neurology. PMID 33441454 DOI: 10.1212/WNL.0000000000011397  0.461
2020 Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, et al. Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. Journal of Neuropathology and Experimental Neurology. PMID 33367843 DOI: 10.1093/jnen/nlaa153  0.787
2020 Buciuc M, Whitwell JL, Kasanuki K, Graff-Radford J, Machulda MM, Duffy JR, Strand EA, Lowe VJ, Graff-Radford NR, Rush BK, Franczak MB, Flanagan ME, Baker MC, Rademakers R, Ross OA, ... ... Bigio EH, et al. Lewy body disease is a contributor to logopenic progressive aphasia phenotype. Annals of Neurology. PMID 33274526 DOI: 10.1002/ana.25979  0.623
2020 Gefen T, Mao Q, Kohler M, Moeller S, Kawles A, Coventry C, Spencer C, Lilek J, Ajroud K, Feldman A, Flanagan M, Rogalski E, Weintraub S, Rademaker A, Geula C, ... ... Bigio E, et al. Primary Progressive Aphasia has a Unique Signature Distinct from Dementia of the Alzheimer's Type and Behavioral Variant Frontotemporal Dementia Regardless of Pathology. Journal of Neuropathology and Experimental Neurology. PMID 33068393 DOI: 10.1093/jnen/nlaa080  0.526
2020 Lamerand S, Shahidehpour R, Ayala I, Gefen T, Mesulam MM, Bigio E, Geula C. Calbindin-D, parvalbumin, and calretinin in young and aged human locus coeruleus. Neurobiology of Aging. 94: 243-249. PMID 32663717 DOI: 10.1016/J.Neurobiolaging.2020.06.006  0.336
2020 McCord MR, Bigio EH, Kam KL, Fischer V, Obeidin F, White CL, Brat DJ, Muller WA, Mao Q. Spinocerebellar Ataxia Type 3: A Case Report and Literature Review. Journal of Neuropathology and Experimental Neurology. PMID 32346735 DOI: 10.1093/Jnen/Nlaa033  0.555
2020 Lee DJ, Bigio EH, Rogalski EJ, Mesulam MM. Speech and Language Presentations of FTLD-TDP Type B Neuropathology. Journal of Neuropathology and Experimental Neurology. PMID 31995205 DOI: 10.1093/Jnen/Nlz132  0.378
2019 Weintraub S, Teylan M, Rader B, Chan KCG, Bollenbeck M, Kukull WA, Coventry C, Rogalski E, Bigio E, Mesulam MM. is a correlate of phenotypic heterogeneity in Alzheimer disease in a national cohort. Neurology. PMID 31704790 DOI: 10.1212/Wnl.0000000000008666  0.447
2019 Jara JH, Gautam M, Kocak N, Xie EF, Mao Q, Bigio EH, Özdinler PH. MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology. Journal of Neuroinflammation. 16: 196. PMID 31666087 DOI: 10.1186/S12974-019-1589-Y  0.508
2019 Ohm DT, Fought AJ, Rademaker A, Kim G, Sridhar J, Coventry C, Gefen T, Weintraub S, Bigio E, Mesulam MM, Rogalski E, Geula C. Neuropathologic basis of in vivo cortical atrophy in the aphasic variant of alzheimer's disease. Brain Pathology (Zurich, Switzerland). PMID 31446630 DOI: 10.1111/Bpa.12783  0.393
2019 Mao Q, Zheng X, Gefen T, Rogalski E, Spencer CL, Rademakers R, Fought AJ, Kohler M, Weintraub S, Xia H, Mesulam MM, Bigio EH. FTLD-TDP With and Without GRN Mutations Cause Different Patterns of CA1 Pathology. Journal of Neuropathology and Experimental Neurology. PMID 31361008 DOI: 10.1093/Jnen/Nlz059  0.471
2019 Borges LG, Rademaker AW, Bigio EH, Mesulam MM, Weintraub S. Apathy and Disinhibition Related to Neuropathology in Amnestic Versus Behavioral Dementias. American Journal of Alzheimer's Disease and Other Dementias. 1533317519853466. PMID 31170813 DOI: 10.1177/1533317519853466  0.343
2019 Apple AC, Mao Q, Bigio E, Bonakdarpour B. Sleep talking and primary progressive aphasia: case study and autopsy findings in a patient with logopenic primary progressive aphasia and dementia with Lewy bodies. Bmj Case Reports. 12. PMID 31133550 DOI: 10.1136/Bcr-2018-228938  0.474
2019 Nishihira Y, Gefen T, Mao Q, Appin C, Kohler M, Walker J, Rademakers R, Rademaker A, Rogalski E, Weintraub S, Geula C, Mesulam MM, Bigio EH. Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes. Acta Neuropathologica. PMID 31065833 DOI: 10.1007/S00401-019-02024-W  0.708
2019 Li Y, Wang D, Li Y, Zhu J, Zhao J, Deng Y, Rogalski EJ, Bigio EH, Rademaker AW, Xia H, Mao Q. A Highly Sensitive Sandwich ELISA to Detect CSF Progranulin: A Potential Biomarker for CNS Disorders. Journal of Neuropathology and Experimental Neurology. PMID 30939191 DOI: 10.1093/Jnen/Nlz022  0.416
2019 Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, ... ... Bigio EH, et al. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathologica. PMID 30739198 DOI: 10.1007/S00401-019-01962-9  0.685
2019 Walker JM, Richardson T, Farrell KW, Fudym Y, Woltjer R, Seshadri S, Bigio EH, White C, Crary JF. O2-08-06: CA2 NEUROFIBRILLARY DEGENERATION AND ASYMMETRY IN PRIMARY AGE-RELATED TAUOPATHY Alzheimer's & Dementia. 15: P557-P558. DOI: 10.1016/J.Jalz.2019.06.4498  0.581
2018 Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, ... ... Bigio EH, et al. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. The Lancet. Neurology. PMID 29724592 DOI: 10.1016/S1474-4422(18)30126-1  0.703
2018 Gefen T, Ahmadian SS, Mao Q, Kim G, Seckin M, Bonakdarpour B, Ramos EM, Coppola G, Rademakers R, Rogalski E, Rademaker A, Weintraub S, Mesulam MM, Geula C, Bigio EH. Combined Pathologies in FTLD-TDP Types A and C. Journal of Neuropathology and Experimental Neurology. PMID 29584904 DOI: 10.1093/Jnen/Nly018  0.541
2018 Rogalski E, Gefen T, Mao Q, Connelly M, Weintraub S, Geula C, Bigio EH, Mesulam MM. Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first ten cases. Hippocampus. PMID 29341318 DOI: 10.1002/Hipo.22828  0.463
2017 Gefen T, Papastefan ST, Rezvanian A, Bigio EH, Weintraub S, Rogalski E, Mesulam MM, Geula C. Von Economo neurons of the anterior cingulate across the lifespan and in Alzheimer's disease. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 99: 69-77. PMID 29175073 DOI: 10.1016/J.Cortex.2017.10.015  0.302
2017 Mao Q, Wang D, Li Y, Kohler M, Wilson J, Parton Z, Shmaltsuyeva B, Gursel D, Rademakers R, Weintraub S, Mesulam MM, Xia H, Bigio EH. Disease and Region Specificity of Granulin Immunopositivities in Alzheimer Disease and Frontotemporal Lobar Degeneration. Journal of Neuropathology and Experimental Neurology. 76: 957-968. PMID 29044416 DOI: 10.1093/Jnen/Nlx085  0.492
2017 Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, et al. Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG). Journal of Neuropathology and Experimental Neurology. PMID 28591867 DOI: 10.1093/Jnen/Nlx041  0.445
2017 Lopez A, Lee SE, Wojta K, Ramos EM, Klein E, Chen J, Boxer AL, Gorno-Tempini ML, Geschwind DH, Schlotawa L, Ogryzko NV, Bigio EH, Rogalski E, Weintraub S, Mesulam MM, et al. A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction. Brain : a Journal of Neurology. PMID 28334843 DOI: 10.1093/Brain/Awx005  0.372
2017 Oboudiyat C, Gefen T, Varelas E, Weintraub S, Rogalski E, Bigio EH, Mesulam MM. Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28196768 DOI: 10.1016/J.Jalz.2017.01.006  0.305
2016 Hakar M, Chandler JP, Bigio EH, Mao Q. Neuroendocrine carcinoma of the pineal parenchyma. The first reported case. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 27742368 DOI: 10.1016/J.Jocn.2016.09.024  0.427
2016 Guo L, Rezvanian A, Kukreja L, Hoveydai R, Bigio EH, Mesulam MM, El Khoury J, Geula C. Postmortem Adult Human Microglia Proliferate in Culture to High Passage and Maintain Their Response to Amyloid-β. Journal of Alzheimer's Disease : Jad. PMID 27567845 DOI: 10.3233/Jad-160394  0.3
2016 Rogalski E, Sridhar J, Rader B, Martersteck A, Chen K, Cobia D, Thompson CK, Weintraub S, Bigio EH, Mesulam MM. Aphasic variant of Alzheimer disease: Clinical, anatomic, and genetic features. Neurology. PMID 27566743 DOI: 10.1212/Wnl.0000000000003165  0.45
2016 Kielb S, Cook A, Wieneke C, Rademaker A, Bigio EH, Mesulam MM, Rogalski E, Weintraub S. Neuropathologic Associations of Learning and Memory in Primary Progressive Aphasia. Jama Neurology. PMID 27183206 DOI: 10.1001/Jamaneurol.2016.0880  0.352
2016 Ringman JM, Monsell S, Ng DW, Zhou Y, Nguyen A, Coppola G, Van Berlo V, Mendez MF, Tung S, Weintraub S, Mesulam MM, Bigio EH, Gitelman DR, Fisher-Hubbard AO, Albin RL, et al. Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database. Journal of Neuropathology and Experimental Neurology. PMID 26888304 DOI: 10.1093/Jnen/Nlv028  0.48
2015 Ernst LM, Bit-Ivan EN, Miller ES, Minturn L, Bigio EH, Weese-Meyer DE. Stillbirth: Correlations Between Brain Injury and Placental Pathology. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. PMID 26492345 DOI: 10.2350/15-06-1658-Oa.1  0.339
2015 Ahmadian SS, Rezvanian A, Peterson M, Weintraub S, Bigio EH, Mesulam MM, Geula C. Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease. Neurobiology of Aging. PMID 26417681 DOI: 10.1016/J.Neurobiolaging.2015.09.001  0.451
2015 Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26327235 DOI: 10.1016/J.Jalz.2015.07.492  0.398
2015 Baker-Nigh A, Vahedi S, Davis EG, Weintraub S, Bigio EH, Klein WL, Geula C. Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease. Brain : a Journal of Neurology. 138: 1722-37. PMID 25732182 DOI: 10.1093/Brain/Awv024  0.409
2015 Gefen T, Peterson M, Papastefan ST, Martersteck A, Whitney K, Rademaker A, Bigio EH, Weintraub S, Rogalski E, Mesulam MM, Geula C. Morphometric and histologic substrates of cingulate integrity in elders with exceptional memory capacity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1781-91. PMID 25632151 DOI: 10.1523/Jneurosci.2998-14.2015  0.338
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Bigio EH, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.438
2015 SantaCruz KS, Rottunda SJ, Meints JP, Bearer EL, Bigio EH, McCarten JR. A case of globular glial tauopathy presenting clinically as alzheimer disease. Alzheimer Disease and Associated Disorders. 29: 82-4. PMID 23751368 DOI: 10.1097/Wad.0B013E318298E531  0.45
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/S00401-014-1349-0  0.48
2014 Fawzi AA, Simonett JM, Purta P, Moss HE, Lowry JL, Deng HX, Siddique N, Sufit R, Bigio EH, Volpe NJ, Siddique T. Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 569-80. PMID 25319030 DOI: 10.3109/21678421.2014.951941  0.305
2014 Gorrie GH, Fecto F, Radzicki D, Weiss C, Shi Y, Dong H, Zhai H, Fu R, Liu E, Li S, Arrat H, Bigio EH, Disterhoft JF, Martina M, Mugnaini E, et al. Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2. Proceedings of the National Academy of Sciences of the United States of America. 111: 14524-9. PMID 25246588 DOI: 10.1073/Pnas.1405741111  0.377
2014 van Blitterswijk M, Mullen B, Wojtas A, Heckman MG, Diehl NN, Baker MC, DeJesus-Hernandez M, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, et al. Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene. Molecular Neurodegeneration. 9: 38. PMID 25239657 DOI: 10.1186/1750-1326-9-38  0.381
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Bigio EH, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.369
2014 Mesulam MM, Rogalski EJ, Wieneke C, Hurley RS, Geula C, Bigio EH, Thompson CK, Weintraub S. Primary progressive aphasia and the evolving neurology of the language network. Nature Reviews. Neurology. 10: 554-69. PMID 25179257 DOI: 10.1038/Nrneurol.2014.159  0.367
2014 van Blitterswijk M, Mullen B, Heckman MG, Baker MC, DeJesus-Hernandez M, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, et al. Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers. Neurobiology of Aging. 35: 2421.e13-7. PMID 24866401 DOI: 10.1016/J.Neurobiolaging.2014.04.016  0.371
2014 Bit-Ivan EN, Lee KH, Gitelman D, Weintraub S, Mesulam M, Rademakers R, Isaacs AM, Hatanpaa KJ, White CL, Mao Q, Akman O, DiMauro S, Bigio EH. Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration. Neuropathology and Applied Neurobiology. 40: 778-82. PMID 24750115 DOI: 10.1111/Nan.12144  0.577
2014 Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EH. A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases. Journal of Neuropathology and Experimental Neurology. 73: 467-73. PMID 24709683 DOI: 10.1097/Nen.0000000000000070  0.4
2014 Mesulam MM, Weintraub S, Rogalski EJ, Wieneke C, Geula C, Bigio EH. Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia. Brain : a Journal of Neurology. 137: 1176-92. PMID 24574501 DOI: 10.1093/Brain/Awu024  0.484
2014 Riascos D, Nicholas A, Samaeekia R, Yukhananov R, Mesulam MM, Bigio EH, Weintraub S, Guo L, Geula C. Alterations of Ca²⁺-responsive proteins within cholinergic neurons in aging and Alzheimer's disease. Neurobiology of Aging. 35: 1325-33. PMID 24461366 DOI: 10.1016/J.Neurobiolaging.2013.12.017  0.404
2014 van Blitterswijk M, Mullen B, Nicholson AM, Bieniek KF, Heckman MG, Baker MC, DeJesus-Hernandez M, Finch NA, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, ... Bigio EH, et al. TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia. Acta Neuropathologica. 127: 397-406. PMID 24385136 DOI: 10.1007/S00401-013-1240-4  0.366
2014 Gefen T, Papastefan S, Peterson M, Kım G, Rogalskı E, Weıntraub S, Bıgıo E, Mesulam M, Geula C. Histopathologic Substrates of Cingulate Integrity in SuperAging: A Stereological Study Neurobiology of Aging. 35: 718. DOI: 10.1016/J.Neurobiolaging.2013.10.048  0.367
2013 van Blitterswijk M, Baker MC, DeJesus-Hernandez M, Ghidoni R, Benussi L, Finger E, Hsiung GY, Kelley BJ, Murray ME, Rutherford NJ, Brown PE, Ravenscroft T, Mullen B, Ash PE, Bieniek KF, ... ... Bigio EH, et al. C9ORF72 repeat expansions in cases with previously identified pathogenic mutations. Neurology. 81: 1332-41. PMID 24027057 DOI: 10.1212/Wnl.0B013E3182A8250C  0.343
2013 Ahmed Z, Bigio EH, Budka H, Dickson DW, Ferrer I, Ghetti B, Giaccone G, Hatanpaa KJ, Holton JL, Josephs KA, Powers J, Spina S, Takahashi H, White CL, Revesz T, et al. Globular glial tauopathies (GGT): consensus recommendations. Acta Neuropathologica. 126: 537-44. PMID 23995422 DOI: 10.1007/S00401-013-1171-0  0.436
2013 Rayaprolu S, Mullen B, Baker M, Lynch T, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Josephs KA, Knopman DS, White CL, Caselli R, et al. TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease. Molecular Neurodegeneration. 8: 19. PMID 23800361 DOI: 10.1186/1750-1326-8-19  0.414
2013 Bigio EH, Wu JY, Deng HX, Bit-Ivan EN, Mao Q, Ganti R, Peterson M, Siddique N, Geula C, Siddique T, Mesulam M. Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid. Acta Neuropathologica. 125: 463-5. PMID 23378033 DOI: 10.1007/S00401-013-1089-6  0.553
2013 Rogalski EJ, Gefen T, Shi J, Samimi M, Bigio E, Weintraub S, Geula C, Mesulam MM. Youthful memory capacity in old brains: anatomic and genetic clues from the Northwestern SuperAging Project. Journal of Cognitive Neuroscience. 25: 29-36. PMID 23198888 DOI: 10.1162/Jocn_A_00300  0.329
2013 Lee KH, Lall RR, Chandler JP, Bigio EH, Mao Q. Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: case report and literature review. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 33: 192-8. PMID 22784446 DOI: 10.1111/J.1440-1789.2012.01337.X  0.476
2013 Bigio EH, Weintraub S, Rademakers R, Baker M, Ahmadian SS, Rademaker A, Weitner BB, Mao Q, Lee KH, Mishra M, Ganti RA, Mesulam MM. Frontotemporal lobar degeneration with TDP-43 proteinopathy and chromosome 9p repeat expansion in C9ORF72: clinicopathologic correlation. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 33: 122-33. PMID 22702520 DOI: 10.1111/J.1440-1789.2012.01332.X  0.575
2012 Rutherford NJ, Heckman MG, Dejesus-Hernandez M, Baker MC, Soto-Ortolaza AI, Rayaprolu S, Stewart H, Finger E, Volkening K, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, et al. Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype. Neurobiology of Aging. 33: 2950.e5-7. PMID 22840558 DOI: 10.1016/J.Neurobiolaging.2012.07.005  0.373
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Bigio EH, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161  0.44
2012 Gefen T, Gasho K, Rademaker A, Lalehzari M, Weintraub S, Rogalski E, Wieneke C, Bigio E, Geula C, Mesulam MM. Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia. Brain : a Journal of Neurology. 135: 1554-65. PMID 22522938 DOI: 10.1093/Brain/Aws076  0.5
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/Nen.0B013E31825018F7  0.433
2012 Nakamura K, Greenwood A, Binder L, Bigio EH, Denial S, Nicholson L, Zhou XZ, Lu KP. Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease. Cell. 149: 232-44. PMID 22464332 DOI: 10.1016/J.Cell.2012.02.016  0.377
2012 Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 1-13. PMID 22265587 DOI: 10.1016/J.Jalz.2011.10.007  0.46
2012 Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathologica. 123: 1-11. PMID 22101365 DOI: 10.1007/S00401-011-0910-3  0.448
2012 Fecto F, Deng H, Chen W, Hong S, Boycott K, Gorrie G, Siddique N, Yang Y, Shi Y, Zhai H, Jiang H, Hirano M, Rampersaud E, Jansen G, Donkervoort S, ... Bigio E, et al. UBQLN2 Mutations in ALS and ALS/Dementia: A Genetic, Functional and Histopathological Analysis (S05.006) Neurology. 78: S05.006-S05.006. DOI: 10.1212/Wnl.78.1_Meetingabstracts.S05.006  0.324
2011 Deng HX, Chen W, Hong ST, Boycott KM, Gorrie GH, Siddique N, Yang Y, Fecto F, Shi Y, Zhai H, Jiang H, Hirano M, Rampersaud E, Jansen GH, Donkervoort S, ... Bigio EH, et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature. 477: 211-5. PMID 21857683 DOI: 10.1038/Nature10353  0.346
2011 Deng HX, Bigio EH, Zhai H, Fecto F, Ajroud K, Shi Y, Yan J, Mishra M, Ajroud-Driss S, Heller S, Sufit R, Siddique N, Mugnaini E, Siddique T. Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations. Archives of Neurology. 68: 1057-61. PMID 21825243 DOI: 10.1001/Archneurol.2011.178  0.305
2011 Armstrong RA, Gearing M, Bigio EH, Cruz-Sanchez FF, Duyckaerts C, Mackenzie IR, Perry RH, Skullerud K, Yokoo H, Cairns NJ. Spatial patterns of FUS-immunoreactive neuronal cytoplasmic inclusions (NCI) in neuronal intermediate filament inclusion disease (NIFID). Journal of Neural Transmission (Vienna, Austria : 1996). 118: 1651-7. PMID 21792670 DOI: 10.1007/S00702-011-0690-X  0.33
2011 Chen Y, Yang M, Deng J, Chen X, Ye Y, Zhu L, Liu J, Ye H, Shen Y, Li Y, Rao EJ, Fushimi K, Zhou X, Bigio EH, Mesulam M, et al. Expression of human FUS protein in Drosophila leads to progressive neurodegeneration. Protein & Cell. 2: 477-86. PMID 21748598 DOI: 10.1007/S13238-011-1065-7  0.35
2011 Guo W, Chen Y, Zhou X, Kar A, Ray P, Chen X, Rao EJ, Yang M, Ye H, Zhu L, Liu J, Xu M, Yang Y, Wang C, Zhang D, ... Bigio EH, et al. An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nature Structural & Molecular Biology. 18: 822-30. PMID 21666678 DOI: 10.1038/Nsmb.2053  0.347
2011 Ross OA, Rutherford NJ, Baker M, Soto-Ortolaza AI, Carrasquillo MM, DeJesus-Hernandez M, Adamson J, Li M, Volkening K, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, et al. Ataxin-2 repeat-length variation and neurodegeneration. Human Molecular Genetics. 20: 3207-12. PMID 21610160 DOI: 10.1093/Hmg/Ddr227  0.376
2011 Page T, Gitcho MA, Mosaheb S, Carter D, Chakraverty S, Perry RH, Bigio EH, Gearing M, Ferrer I, Goate AM, Cairns NJ, Thorpe JR. FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy. Journal of Molecular Neuroscience : Mn. 45: 409-21. PMID 21603978 DOI: 10.1007/S12031-011-9549-8  0.334
2011 Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, ... ... Bigio E, et al. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Archives of Neurology. 68: 488-97. PMID 21482928 DOI: 10.1001/Archneurol.2011.53  0.328
2011 Rogalski EJ, Rademaker A, Harrison TM, Helenowski I, Johnson N, Bigio E, Mishra M, Weintraub S, Mesulam MM. ApoE E4 is a susceptibility factor in amnestic but not aphasic dementias. Alzheimer Disease and Associated Disorders. 25: 159-63. PMID 21346518 DOI: 10.1097/Wad.0B013E318201F249  0.459
2011 Dakson A, Yokota O, Esiri M, Bigio EH, Horan M, Pendleton N, Richardson A, Neary D, Snowden JS, Robinson A, Davidson YS, Mann DM. Granular expression of prolyl-peptidyl isomerase PIN1 is a constant and specific feature of Alzheimer's disease pathology and is independent of tau, Aβ and TDP-43 pathology. Acta Neuropathologica. 121: 635-49. PMID 21243369 DOI: 10.1007/S00401-011-0798-Y  0.486
2011 Armstrong RA, Gearing M, Bigio EH, Cruz-Sanchez FF, Duyckaerts C, Mackenzie IR, Perry RH, Skullerud K, Yokoo H, Cairns NJ. The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease. Acta Neuropathologica. 121: 219-28. PMID 20886222 DOI: 10.1007/S00401-010-0753-3  0.382
2011 Dequen F, Cairns NJ, Bigio EH, Julien JP. Gigaxonin mutation analysis in patients with NIFID. Neurobiology of Aging. 32: 1528-9. PMID 19782434 DOI: 10.1016/J.Neurobiolaging.2009.08.018  0.382
2010 Deng HX, Zhai H, Bigio EH, Yan J, Fecto F, Ajroud K, Mishra M, Ajroud-Driss S, Heller S, Sufit R, Siddique N, Mugnaini E, Siddique T. FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis. Annals of Neurology. 67: 739-48. PMID 20517935 DOI: 10.1002/Ana.22051  0.353
2010 Yokota O, Davidson Y, Bigio EH, Ishizu H, Terada S, Arai T, Hasegawa M, Akiyama H, Sikkink S, Pickering-Brown S, Mann DM. Phosphorylated TDP-43 pathology and hippocampal sclerosis in progressive supranuclear palsy. Acta Neuropathologica. 120: 55-66. PMID 20512649 DOI: 10.1007/S00401-010-0702-1  0.421
2010 Urwin H, Josephs KA, Rohrer JD, Mackenzie IR, Neumann M, Authier A, Seelaar H, Van Swieten JC, Brown JM, Johannsen P, Nielsen JE, Holm IE, Dickson DW, Rademakers R, ... ... Bigio EH, et al. FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathologica. 120: 33-41. PMID 20490813 DOI: 10.1007/S00401-010-0698-6  0.435
2010 Gliebus G, Bigio EH, Gasho K, Mishra M, Caplan D, Mesulam MM, Geula C. Asymmetric TDP-43 distribution in primary progressive aphasia with progranulin mutation. Neurology. 74: 1607-10. PMID 20479359 DOI: 10.1212/Wnl.0B013E3181Df0A1B  0.423
2010 Perry A, Burton SS, Fuller GN, Robinson CA, Palmer CA, Resch L, Bigio EH, Gujrati M, Rosenblum MK. Oligodendroglial neoplasms with ganglioglioma-like maturation: a diagnostic pitfall. Acta Neuropathologica. 120: 237-52. PMID 20464403 DOI: 10.1007/S00401-010-0695-9  0.338
2010 Bigio EH, Mishra M, Hatanpaa KJ, White CL, Johnson N, Rademaker A, Weitner BB, Deng HX, Dubner SD, Weintraub S, Mesulam M. TDP-43 pathology in primary progressive aphasia and frontotemporal dementia with pathologic Alzheimer disease. Acta Neuropathologica. 120: 43-54. PMID 20361198 DOI: 10.1007/S00401-010-0681-2  0.777
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Bigio EH, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  0.329
2010 Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathologica. 119: 1-4. PMID 19924424 DOI: 10.1007/S00401-009-0612-2  0.355
2010 Chauhan NB, Bigio EH, Geula C, Gatto R. P4-033: Is Diabetes the Pre-disposing Co-morbid Trigger for Sporadic Alzheimer's Disease Alzheimer's & Dementia. 6: e30-e30. DOI: 10.1016/J.Jalz.2010.08.093  0.321
2009 Foulds PG, Davidson Y, Mishra M, Hobson DJ, Humphreys KM, Taylor M, Johnson N, Weintraub S, Akiyama H, Arai T, Hasegawa M, Bigio EH, Benson FE, Allsop D, Mann DM. Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathologica. 118: 647-58. PMID 19823856 DOI: 10.1007/S00401-009-0594-0  0.388
2009 Gitcho MA, Bigio EH, Mishra M, Johnson N, Weintraub S, Mesulam M, Rademakers R, Chakraverty S, Cruchaga C, Morris JC, Goate AM, Cairns NJ. TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy. Acta Neuropathologica. 118: 633-45. PMID 19618195 DOI: 10.1007/S00401-009-0571-7  0.366
2009 Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, et al. Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathologica. 117: 15-8. PMID 19015862 DOI: 10.1007/S00401-008-0460-5  0.348
2008 Schaffer BA, Bertram L, Miller BL, Mullin K, Weintraub S, Johnson N, Bigio EH, Mesulam M, Wiedau-Pazos M, Jackson GR, Cummings JL, Cantor RM, Levey AI, Tanzi RE, Geschwind DH. Association of GSK3B with Alzheimer disease and frontotemporal dementia. Archives of Neurology. 65: 1368-74. PMID 18852354 DOI: 10.1001/Archneur.65.10.1368  0.478
2008 Rutherford NJ, Zhang YJ, Baker M, Gass JM, Finch NA, Xu YF, Stewart H, Kelley BJ, Kuntz K, Crook RJ, Sreedharan J, Vance C, Sorenson E, Lippa C, Bigio EH, et al. Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. Plos Genetics. 4: e1000193. PMID 18802454 DOI: 10.1371/Journal.Pgen.1000193  0.336
2008 Mesulam M, Wicklund A, Johnson N, Rogalski E, Léger GC, Rademaker A, Weintraub S, Bigio EH. Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia. Annals of Neurology. 63: 709-19. PMID 18412267 DOI: 10.1002/Ana.21388  0.471
2008 Hatanpaa KJ, Bigio EH, Cairns NJ, Womack KB, Weintraub S, Morris JC, Foong C, Xiao G, Hladik C, Mantanona TY, White CL. TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study. Journal of Neuropathology and Experimental Neurology. 67: 271-9. PMID 18379440 DOI: 10.1097/Nen.0B013E31816A12A6  0.435
2008 Gitcho MA, Baloh RH, Chakraverty S, Mayo K, Norton JB, Levitch D, Hatanpaa KJ, White CL, Bigio EH, Caselli R, Baker M, Al-Lozi MT, Morris JC, Pestronk A, Rademakers R, et al. TDP-43 A315T mutation in familial motor neuron disease. Annals of Neurology. 63: 535-8. PMID 18288693 DOI: 10.1002/Ana.21344  0.34
2008 Mukherjee O, Wang J, Gitcho M, Chakraverty S, Taylor-Reinwald L, Shears S, Kauwe JS, Norton J, Levitch D, Bigio EH, Hatanpaa KJ, White CL, Morris JC, Cairns NJ, Goate A. Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia. Human Mutation. 29: 512-21. PMID 18183624 DOI: 10.1002/Humu.20681  0.413
2008 De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL. Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers. Neurobiology of Aging. 29: 1334-47. PMID 17403556 DOI: 10.1016/J.Neurobiolaging.2007.02.029  0.41
2008 Gitcho MA, Baloh RH, Chakraverty S, Mayo K, Norton JB, Levitch D, Hatanpaa KJ, White CH, Bigio EH, Caselli R, Baker M, Al-Lozi MT, Morris JC, Pestronk A, Rademakers R, et al. P3-287: TDP-43 A315T mutation in familial motor neuron disease Alzheimer's & Dementia. 4: T606-T607. DOI: 10.1016/J.Jalz.2008.05.1855  0.314
2007 Cairns NJ, Neumann M, Bigio EH, Holm IE, Troost D, Hatanpaa KJ, Foong C, White CL, Schneider JA, Kretzschmar HA, Carter D, Taylor-Reinwald L, Paulsmeyer K, Strider J, Gitcho M, et al. TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. The American Journal of Pathology. 171: 227-40. PMID 17591968 DOI: 10.2353/Ajpath.2007.070182  0.377
2007 Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, et al. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathologica. 114: 5-22. PMID 17579875 DOI: 10.1007/S00401-007-0237-2  0.444
2007 Mishra M, Paunesku T, Woloschak GE, Siddique T, Zhu LJ, Lin S, Greco K, Bigio EH. Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions. Acta Neuropathologica. 114: 81-94. PMID 17569064 DOI: 10.1007/S00401-007-0240-7  0.31
2007 Davion S, Johnson N, Weintraub S, Mesulam MM, Engberg A, Mishra M, Baker M, Adamson J, Hutton M, Rademakers R, Bigio EH. Clinicopathologic correlation in PGRN mutations. Neurology. 69: 1113-21. PMID 17522386 DOI: 10.1212/01.Wnl.0000267701.58488.69  0.376
2007 Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Annals of Neurology. 61: 427-34. PMID 17469116 DOI: 10.1002/Ana.21147  0.362
2007 Guillozet-Bongaarts AL, Glajch KE, Libson EG, Cahill ME, Bigio E, Berry RW, Binder LI. Phosphorylation and cleavage of tau in non-AD tauopathies. Acta Neuropathologica. 113: 513-20. PMID 17357802 DOI: 10.1007/S00401-007-0209-6  0.456
2007 Lambert MP, Velasco PT, Chang L, Viola KL, Fernandez S, Lacor PN, Khuon D, Gong Y, Bigio EH, Shaw P, De Felice FG, Krafft GA, Klein WL. Monoclonal antibodies that target pathological assemblies of Abeta. Journal of Neurochemistry. 100: 23-35. PMID 17116235 DOI: 10.1111/J.1471-4159.2006.04157.X  0.37
2007 Grudzien A, Shaw P, Weintraub S, Bigio E, Mash DC, Mesulam MM. Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease. Neurobiology of Aging. 28: 327-35. PMID 16574280 DOI: 10.1016/J.Neurobiolaging.2006.02.007  0.44
2007 Bigio EH, Mishra M, Johnson N, Mao H, Mesulam M. Characterization of TDP43 protein in primary progressive aphasia (PPA) and frontotemporal dementia (FTD) with Alzheimer disease (AD) pathology Journal of Neuropathology and Experimental Neurology. 66: 421. DOI: 10.1097/01.Jnen.0000268988.44653.7F  0.467
2007 Hatanpaa KJ, Bigio EH, Cairns NJ, Schneider JA, Foong C, Hladik C, Shang P, White CL. TDP-43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a Midwest-Southwest Consortium for FTLD study Journal of Neuropathology and Experimental Neurology. 66: 425. DOI: 10.1096/Fasebj.21.5.A24-C  0.373
2007 Bigio EH, Engberg A, Mishra M, Johnson N, Mesulam M. Basophilic inclusion body disease with novel ubiquitinated extracellular, cytoplasmic, and intranuclear inclusions Journal of Neuropathology and Experimental Neurology. 66: 423. DOI: 10.1096/Fasebj.21.5.A23-B  0.31
2006 Reynolds MR, Reyes JF, Fu Y, Bigio EH, Guillozet-Bongaarts AL, Berry RW, Binder LI. Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10636-45. PMID 17050703 DOI: 10.1523/Jneurosci.2143-06.2006  0.428
2006 Gass J, Cannon A, Mackenzie IR, Boeve B, Baker M, Adamson J, Crook R, Melquist S, Kuntz K, Petersen R, Josephs K, Pickering-Brown SM, Graff-Radford N, Uitti R, Dickson D, ... ... Bigio E, et al. Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. Human Molecular Genetics. 15: 2988-3001. PMID 16950801 DOI: 10.1093/Hmg/Ddl241  0.333
2006 Shiarli AM, Jennings R, Shi J, Bailey K, Davidson Y, Tian J, Bigio EH, Ghetti B, Murrell JR, Delisle MB, Mirra S, Crain B, Zolo P, Arima K, Iseki E, et al. Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease. Neuropathology and Applied Neurobiology. 32: 374-87. PMID 16866983 DOI: 10.1111/J.1365-2990.2006.00736.X  0.437
2006 Bonte FJ, Harris TS, Hynan LS, Bigio EH, White CL. Tc-99m HMPAO SPECT in the differential diagnosis of the dementias with histopathologic confirmation. Clinical Nuclear Medicine. 31: 376-8. PMID 16785801 DOI: 10.1097/01.Rlu.0000222736.81365.63  0.318
2006 Deng HX, Shi Y, Furukawa Y, Zhai H, Fu R, Liu E, Gorrie GH, Khan MS, Hung WY, Bigio EH, Lukas T, Dal Canto MC, O'Halloran TV, Siddique T. Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 103: 7142-7. PMID 16636275 DOI: 10.1073/Pnas.0602046103  0.302
2006 de Silva R, Lashley T, Strand C, Shiarli AM, Shi J, Tian J, Bailey KL, Davies P, Bigio EH, Arima K, Iseki E, Murayama S, Kretzschmar H, Neumann M, Lippa C, et al. An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathologica. 111: 329-40. PMID 16552612 DOI: 10.1007/S00401-006-0048-X  0.406
2006 Momeni P, Cairns NJ, Perry RH, Bigio EH, Gearing M, Singleton AB, Hardy J. Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID). Neurobiology of Aging. 27: 778.e1-778.e6. PMID 16005115 DOI: 10.1016/J.Neurobiolaging.2005.03.030  0.409
2006 Yan J, Siddique N, Slifer S, Bigio E, Mao H, Chen W, Liu E, Shi Y, Khan S, Haines J, Pericak-Vance M, Siddique T. A Major Novel Locus for ALS/FTD on Chromosome 9p21 and its Pathological Correlates: S61.006 Neurology. 67: 186-186. DOI: 10.1212/01.Wnl.0000234887.27166.69  0.422
2006 Weintraub S, Teylan M, Rader B, Bollenbeck M, Kukull WA, Rogalski EJ, Bigio EH, Mesulam M. P4-332: APOE4 IS NOT A RISK FACTOR FOR ALZHEIMER'S DISEASE PATHOLOGY IN PPA, IRRESPECTIVE OF CLINICAL SUBTYPE Alzheimer's & Dementia. 14: P1593-P1593. DOI: 10.1016/J.Jalz.2018.07.155  0.388
2006 Ohm DT, Kim G, Gefen T, Rademaker A, Weintraub S, Bigio EH, Mesulam M, Rogalski EJ, Geula C. P2-169: NEUROFIBRILLARY TANGLES PREDICT IN VIVO CORTICAL ATROPHY IN PRIMARY PROGRESSIVE APHASIA WITH ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P733-P733. DOI: 10.1016/J.Jalz.2018.06.856  0.392
2006 Dunlop SR, Lalehzari N, Ohm DT, Kim G, Weintraub S, Bigio EH, Mesulam M, Geula C. P3-460: VULNERABILITY OF THE CHOLINERGIC BASAL FOREBRAIN TO AD VERSUS FTLD-TDP PATHOLOGY IN PRIMARY PROGRESSIVE APHASIA Alzheimer's & Dementia. 14: P1295-P1295. DOI: 10.1016/J.Jalz.2018.06.1824  0.411
2005 Guillozet-Bongaarts AL, Garcia-Sierra F, Reynolds MR, Horowitz PM, Fu Y, Wang T, Cahill ME, Bigio EH, Berry RW, Binder LI. Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease. Neurobiology of Aging. 26: 1015-22. PMID 15748781 DOI: 10.1016/J.Neurobiolaging.2004.09.019  0.413
2004 Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10191-200. PMID 15537891 DOI: 10.1523/Jneurosci.3432-04.2004  0.395
2004 Cairns NJ, Grossman M, Arnold SE, Burn DJ, Jaros E, Perry RH, Duyckaerts C, Stankoff B, Pillon B, Skullerud K, Cruz-Sanchez FF, Bigio EH, Mackenzie IR, Gearing M, Juncos JL, et al. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Neurology. 63: 1376-84. PMID 15505152 DOI: 10.1212/01.Wnl.0000139809.16817.Dd  0.314
2004 Berry RW, Sweet AP, Clark FA, Lagalwar S, Lapin BR, Wang T, Topgi S, Guillozet-Bongaarts AL, Cochran EJ, Bigio EH, Binder LI. Tau epitope display in progressive supranuclear palsy and corticobasal degeneration. Journal of Neurocytology. 33: 287-95. PMID 15475684 DOI: 10.1023/B:Neur.0000044190.96426.B9  0.455
2004 Bigio EH, Johnson NA, Rademaker AW, Fung BB, Mesulam MM, Siddique N, Dellefave L, Caliendo J, Freeman S, Siddique T. Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology. 63: 801-11. PMID 15330335 DOI: 10.1093/Jnen/63.8.801  0.379
2004 Hatanpaa KJ, Blass DM, Pletnikova O, Crain BJ, Bigio EH, Hedreen JC, White CL, Troncoso JC. Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia. Neurology. 63: 538-42. PMID 15304590 DOI: 10.1212/01.Wnl.0000129543.46734.C0  0.47
2004 Lipton AM, Benavides R, Hynan LS, Bonte FJ, Harris TS, White CL, Bigio EH. Lateralization on neuroimaging does not differentiate frontotemporal lobar degeneration from Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 17: 324-7. PMID 15178946 DOI: 10.1159/000077164  0.409
2004 Cairns NJ, Uryu K, Bigio EH, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Arnold SE, Lee VM, Trojanowski JQ. alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases. Acta Neuropathologica. 108: 213-23. PMID 15170578 DOI: 10.1007/S00401-004-0882-7  0.371
2004 Cairns NJ, Zhukareva V, Uryu K, Zhang B, Bigio E, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Lee VM, Trojanowski JQ. alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. The American Journal of Pathology. 164: 2153-61. PMID 15161649 DOI: 10.1016/S0002-9440(10)63773-X  0.405
2003 Weiner MF, Hynan LS, Parikh B, Zaki N, White CL, Bigio EH, Lipton AM, Martin-Cook K, Svetlik DA, Cullum CM, Vobach S, Rosenberg RN. Can alzheimer's disease and dementias with Lewy bodies be distinguished clinically? Journal of Geriatric Psychiatry and Neurology. 16: 245-50. PMID 14653435 DOI: 10.1177/0891988703258671  0.451
2003 Hogg M, Grujic ZM, Baker M, Demirci S, Guillozet AL, Sweet AP, Herzog LL, Weintraub S, Mesulam MM, LaPointe NE, Gamblin TC, Berry RW, Binder LI, de Silva R, Lees A, ... ... Bigio EH, et al. The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy. Acta Neuropathologica. 106: 323-36. PMID 12883828 DOI: 10.1007/S00401-003-0734-X  0.376
2003 Bigio EH, Reisch JS, White CL, Satumtira S, Sontag E, Bonte FJ. Synapse loss may be a minor contributor to decreased regional cerebral blood flow in Alzheimer disease. Dementia and Geriatric Cognitive Disorders. 15: 72-8. PMID 12566595 DOI: 10.1159/000067970  0.373
2002 Morris HR, Baker M, Yasojima K, Houlden H, Khan MN, Wood NW, Hardy J, Grossman M, Trojanowski J, Revesz T, Bigio EH, Bergeron C, Janssen JC, McGeer PL, Rossor MN, et al. Analysis of tau haplotypes in Pick's disease. Neurology. 59: 443-5. PMID 12177383 DOI: 10.1212/Wnl.59.3.443  0.403
2001 Lipton AM, Cullum CM, Satumtira S, Sontag E, Hynan LS, White CL, Bigio EH. Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias. Archives of Neurology. 58: 1233-9. PMID 11493163 DOI: 10.1001/Archneur.58.8.1233  0.428
2001 Houlden H, Baker M, Morris HR, MacDonald N, Pickering-Brown S, Adamson J, Lees AJ, Rossor MN, Quinn NP, Kertesz A, Khan MN, Hardy J, Lantos PL, St George-Hyslop P, Munoz DG, ... ... Bigio EH, et al. Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. Neurology. 56: 1702-6. PMID 11425937 DOI: 10.1212/Wnl.56.12.1702  0.403
2001 Bigio EH, Vono MB, Satumtira S, Adamson J, Sontag E, Hynan LS, White CL, Baker M, Hutton M. Cortical synapse loss in progressive supranuclear palsy. Journal of Neuropathology and Experimental Neurology. 60: 403-10. PMID 11379815 DOI: 10.1093/Jnen/60.5.403  0.758
2001 Bigio EH, Lipton AM, Yen SH, Hutton ML, Baker M, Nacharaju P, White CL, Davies P, Lin W, Dickson DW. Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia. Journal of Neuropathology and Experimental Neurology. 60: 328-41. PMID 11305868 DOI: 10.1093/Jnen/60.4.328  0.45
2000 Honig LS, Chambliss DD, Bigio EH, Carroll SL, Elliott JL. Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls. Neurology. 55: 1082-8. PMID 11071482 DOI: 10.1212/Wnl.55.8.1082  0.346
1999 Bigio EH, Colvin SM, Mickey BE, White CL, Rushing EJ. Radiation change versus recurrent astrocytoma: diagnostic utility of the proliferation index? Journal of Neuro-Oncology. 41: 55-63. PMID 10222423 DOI: 10.1023/A:1006112228001  0.714
1999 Bigio EH, Brown DF, White CL. Progressive supranuclear palsy with dementia: cortical pathology. Journal of Neuropathology and Experimental Neurology. 58: 359-64. PMID 10218631 DOI: 10.1097/00005072-199904000-00006  0.469
1998 Brown DF, Risser RC, Bigio EH, Tripp P, Stiegler A, Welch E, Eagan KP, Hladik CL, White CL. Neocortical synapse density and Braak stage in the Lewy body variant of Alzheimer disease: a comparison with classic Alzheimer disease and normal aging. Journal of Neuropathology and Experimental Neurology. 57: 955-60. PMID 9786245 DOI: 10.1097/00005072-199810000-00007  0.617
1998 Brown DF, Dababo MA, Bigio EH, Risser RC, Eagan KP, Hladik CL, White CL. Neuropathologic evidence that the Lewy body variant of Alzheimer disease represents coexistence of Alzheimer disease and idiopathic Parkinson disease. Journal of Neuropathology and Experimental Neurology. 57: 39-46. PMID 9600196 DOI: 10.1097/00005072-199801000-00006  0.796
1998 Bigio EH, Fontaine CS, Dababo MA, Prahlow JA, Chason DP, Weiner MF, White CL. Dementia associated with cortical dysplasia. Acta Neuropathologica. 95: 193-8. PMID 9498056 DOI: 10.1007/S004010050786  0.748
1997 Bonte FJ, Weiner MF, Bigio EH, White CL. Brain blood flow in the dementias: SPECT with histopathologic correlation in 54 patients. Radiology. 202: 793-7. PMID 9051035 DOI: 10.1148/Radiology.202.3.9051035  0.374
1993 Bonte FJ, Tintner R, Weiner MF, Bigio EH, White CL. Brain blood flow in the dementias: SPECT with histopathologic correlation. Radiology. 186: 361-5. PMID 8421735 DOI: 10.1148/Radiology.186.2.8421735  0.361
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