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Eileen H. Bigio, MD, University of Texas Medical Branch, MSc - Publications

Affiliations: 
Pathology Northwestern University, Evanston, IL 
Area:
Alzheimer's disease and related disorders
Website:
http://www.pathology.northwestern.edu/Faculty/FacultyBio.cfm?ID=2

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nishihira Y, Gefen T, Mao Q, Appin C, Kohler M, Walker J, Rademakers R, Rademaker A, Rogalski E, Weintraub S, Geula C, Mesulam MM, Bigio EH. Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes. Acta Neuropathologica. PMID 31065833 DOI: 10.1007/s00401-019-02024-w  0.48
2019 Li Y, Wang D, Li Y, Zhu J, Zhao J, Deng Y, Rogalski EJ, Bigio EH, Rademaker AW, Xia H, Mao Q. A Highly Sensitive Sandwich ELISA to Detect CSF Progranulin: A Potential Biomarker for CNS Disorders. Journal of Neuropathology and Experimental Neurology. PMID 30939191 DOI: 10.1093/jnen/nlz022  0.48
2019 Mesulam MM, Nelson MJ, Hyun J, Rader B, Hurley RS, Rademakers R, Baker MC, Bigio EH, Weintraub S. Preferential Disruption of Auditory Word Representations in Primary Progressive Aphasia With the Neuropathology of FTLD-TDP Type A. Cognitive and Behavioral Neurology : Official Journal of the Society For Behavioral and Cognitive Neurology. 32: 46-53. PMID 30896577 DOI: 10.1097/WNN.0000000000000180  0.32
2019 Rogalski EJ, Sridhar J, Martersteck A, Rader B, Cobia D, Arora AK, Fought AJ, Bigio EH, Weintraub S, Mesulam MM, Rademaker A. Clinical and cortical decline in the aphasic variant of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30765195 DOI: 10.1016/j.jalz.2018.12.003  0.32
2019 Kim G, Bolbolan K, Shahidehpour R, Jamshidi P, Gefen T, Ayala IA, Weintraub S, Bigio EH, Mesulam MM, Geula C. Morphology and Distribution of TDP-43 Pre-inclusions in Primary Progressive Aphasia. Journal of Neuropathology and Experimental Neurology. PMID 30753613 DOI: 10.1093/jnen/nlz005  0.32
2019 Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, ... ... Bigio EH, et al. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathologica. PMID 30739198 DOI: 10.1007/s00401-019-01962-9  0.64
2018 Ramos EM, Dokuru DR, Van Berlo V, Wojta K, Wang Q, Huang AY, Miller ZA, Karydas AM, Bigio EH, Rogalski E, Weintraub S, Rader B, Miller BL, Gorno-Tempini ML, Mesulam MM, et al. Genetic screen in a large series of patients with primary progressive aphasia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30599136 DOI: 10.1016/j.jalz.2018.10.009  0.32
2018 Mesulam MM, Rader BM, Sridhar J, Nelson MJ, Hyun J, Rademaker A, Geula C, Bigio EH, Thompson CK, Gefen TD, Weintraub S, Rogalski EJ. Word comprehension in temporal cortex and Wernicke area: A PPA perspective. Neurology. PMID 30578374 DOI: 10.1212/WNL.0000000000006788  0.32
2018 Huentelman MJ, Piras IS, Siniard AL, De Both MD, Richholt RF, Balak CD, Jamshidi P, Bigio EH, Weintraub S, Loyer ET, Mesulam MM, Geula C, Rogalski EJ. Associations of Gene Variants With Superior Memory in SuperAgers. Frontiers in Aging Neuroscience. 10: 155. PMID 29896098 DOI: 10.3389/fnagi.2018.00155  0.32
2018 Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, ... ... Bigio EH, et al. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. The Lancet. Neurology. PMID 29724592 DOI: 10.1016/S1474-4422(18)30126-1  0.64
2018 Kim G, Bolbolan K, Gefen T, Weintraub S, Bigio EH, Rogalski E, Mesulam MM, Geula C. Atrophy and microglial distribution in primary progressive aphasia with TDP-43. Annals of Neurology. PMID 29665116 DOI: 10.1002/ana.25240  0.32
2018 Gefen T, Ahmadian SS, Mao Q, Kim G, Seckin M, Bonakdarpour B, Ramos EM, Coppola G, Rademakers R, Rogalski E, Rademaker A, Weintraub S, Mesulam MM, Geula C, Bigio EH. Combined Pathologies in FTLD-TDP Types A and C. Journal of Neuropathology and Experimental Neurology. PMID 29584904 DOI: 10.1093/jnen/nly018  0.48
2018 Rogalski E, Gefen T, Mao Q, Connelly M, Weintraub S, Geula C, Bigio EH, Mesulam MM. Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first ten cases. Hippocampus. PMID 29341318 DOI: 10.1002/hipo.22828  0.48
2018 Kim G, Vahedi S, Gefen T, Weintraub S, Bigio EH, Mesulam MM, Geula C. Asymmetric TDP pathology in primary progressive aphasia with right hemisphere language dominance. Neurology. PMID 29305438 DOI: 10.1212/WNL.0000000000004891  0.32
2017 Gefen T, Papastefan ST, Rezvanian A, Bigio EH, Weintraub S, Rogalski E, Mesulam MM, Geula C. Von Economo neurons of the anterior cingulate across the lifespan and in Alzheimer's disease. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 99: 69-77. PMID 29175073 DOI: 10.1016/j.cortex.2017.10.015  0.32
2017 Mao Q, Wang D, Li Y, Kohler M, Wilson J, Parton Z, Shmaltsuyeva B, Gursel D, Rademakers R, Weintraub S, Mesulam MM, Xia H, Bigio EH. Disease and Region Specificity of Granulin Immunopositivities in Alzheimer Disease and Frontotemporal Lobar Degeneration. Journal of Neuropathology and Experimental Neurology. 76: 957-968. PMID 29044416 DOI: 10.1093/jnen/nlx085  0.48
2017 Jara JH, Genç B, Stanford MJ, Pytel P, Roos RP, Weintraub S, Mesulam MM, Bigio EH, Miller RJ, Özdinler PH. Evidence for an early innate immune response in the motor cortex of ALS. Journal of Neuroinflammation. 14: 129. PMID 28651542 DOI: 10.1186/s12974-017-0896-4  0.32
2017 Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, et al. Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG). Journal of Neuropathology and Experimental Neurology. PMID 28591867 DOI: 10.1093/jnen/nlx041  0.64
2017 Lopez A, Lee SE, Wojta K, Ramos EM, Klein E, Chen J, Boxer AL, Gorno-Tempini ML, Geschwind DH, Schlotawa L, Ogryzko NV, Bigio EH, Rogalski E, Weintraub S, Mesulam MM, et al. A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction. Brain : a Journal of Neurology. PMID 28334843 DOI: 10.1093/brain/awx005  0.32
2017 Oboudiyat C, Gefen T, Varelas E, Weintraub S, Rogalski E, Bigio EH, Mesulam MM. Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28196768 DOI: 10.1016/j.jalz.2017.01.006  0.32
2016 Hakar M, Chandler JP, Bigio EH, Mao Q. Neuroendocrine carcinoma of the pineal parenchyma. The first reported case. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 27742368 DOI: 10.1016/j.jocn.2016.09.024  0.48
2016 Rogalski E, Sridhar J, Rader B, Martersteck A, Chen K, Cobia D, Thompson CK, Weintraub S, Bigio EH, Mesulam MM. Aphasic variant of Alzheimer disease: Clinical, anatomic, and genetic features. Neurology. PMID 27566743 DOI: 10.1212/WNL.0000000000003165  0.32
2016 Kielb S, Cook A, Wieneke C, Rademaker A, Bigio EH, Mesulam MM, Rogalski E, Weintraub S. Neuropathologic Associations of Learning and Memory in Primary Progressive Aphasia. Jama Neurology. PMID 27183206 DOI: 10.1001/jamaneurol.2016.0880  0.32
2016 Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, et al. Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. Cell. PMID 27114033 DOI: 10.1016/j.cell.2016.04.001  0.32
2016 Ringman JM, Monsell S, Ng DW, Zhou Y, Nguyen A, Coppola G, Van Berlo V, Mendez MF, Tung S, Weintraub S, Mesulam MM, Bigio EH, Gitelman DR, Fisher-Hubbard AO, Albin RL, et al. Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database. Journal of Neuropathology and Experimental Neurology. PMID 26888304 DOI: 10.1093/jnen/nlv028  0.52
2015 Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, ... ... Bigio EH, et al. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica. PMID 26659578 DOI: 10.1007/s00401-015-1509-x  0.64
2015 Ahmadian SS, Rezvanian A, Peterson M, Weintraub S, Bigio EH, Mesulam MM, Geula C. Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease. Neurobiology of Aging. PMID 26417681 DOI: 10.1016/j.neurobiolaging.2015.09.001  0.32
2015 Deng J, Yang M, Chen Y, Chen X, Liu J, Sun S, Cheng H, Li Y, Bigio EH, Mesulam M, Xu Q, Du S, Fushimi K, Zhu L, Wu JY. FUS Interacts with HSP60 to Promote Mitochondrial Damage. Plos Genetics. 11: e1005357. PMID 26335776 DOI: 10.1371/journal.pgen.1005357  0.52
2015 Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26327235 DOI: 10.1016/j.jalz.2015.07.492  0.52
2015 Oboudiyat C, Bigio EH, Bonakdarpour B, Baker MC, Rademakers R, Weintraub S, Mesulam MM. Diffuse leukoencephalopathy with spheroids presenting as primary progressive aphasia. Neurology. 85: 652-3. PMID 26203093 DOI: 10.1212/WNL.0000000000001851  0.32
2015 Baker-Nigh A, Vahedi S, Davis EG, Weintraub S, Bigio EH, Klein WL, Geula C. Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease. Brain : a Journal of Neurology. 138: 1722-37. PMID 25732182 DOI: 10.1093/brain/awv024  0.52
2015 Gefen T, Peterson M, Papastefan ST, Martersteck A, Whitney K, Rademaker A, Bigio EH, Weintraub S, Rogalski E, Mesulam MM, Geula C. Morphometric and histologic substrates of cingulate integrity in elders with exceptional memory capacity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1781-91. PMID 25632151 DOI: 10.1523/JNEUROSCI.2998-14.2015  0.52
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Bigio EH, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/jamaneurol.2014.2157  0.52
2015 SantaCruz KS, Rottunda SJ, Meints JP, Bearer EL, Bigio EH, McCarten JR. A case of globular glial tauopathy presenting clinically as alzheimer disease. Alzheimer Disease and Associated Disorders. 29: 82-4. PMID 23751368 DOI: 10.1097/WAD.0b013e318298e531  0.52
2014 Rogalski EJ, Rademaker A, Wieneke C, Bigio EH, Weintraub S, Mesulam MM. Association between the prevalence of learning disabilities and primary progressive aphasia. Jama Neurology. 71: 1576-7. PMID 25486208 DOI: 10.1001/jamaneurol.2014.2805  0.52
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/s00401-014-1349-0  0.52
2014 Fawzi AA, Simonett JM, Purta P, Moss HE, Lowry JL, Deng HX, Siddique N, Sufit R, Bigio EH, Volpe NJ, Siddique T. Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 569-80. PMID 25319030 DOI: 10.3109/21678421.2014.951941  0.52
2014 van Blitterswijk M, Mullen B, Wojtas A, Heckman MG, Diehl NN, Baker MC, DeJesus-Hernandez M, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, et al. Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene. Molecular Neurodegeneration. 9: 38. PMID 25239657 DOI: 10.1186/1750-1326-9-38  0.64
2014 Mesulam MM, Rogalski EJ, Wieneke C, Hurley RS, Geula C, Bigio EH, Thompson CK, Weintraub S. Primary progressive aphasia and the evolving neurology of the language network. Nature Reviews. Neurology. 10: 554-69. PMID 25179257 DOI: 10.1038/nrneurol.2014.159  0.52
2014 van Blitterswijk M, Mullen B, Heckman MG, Baker MC, DeJesus-Hernandez M, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, et al. Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers. Neurobiology of Aging. 35: 2421.e13-7. PMID 24866401 DOI: 10.1016/j.neurobiolaging.2014.04.016  0.52
2014 Bit-Ivan EN, Lee KH, Gitelman D, Weintraub S, Mesulam M, Rademakers R, Isaacs AM, Hatanpaa KJ, White CL, Mao Q, Akman O, DiMauro S, Bigio EH. Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration. Neuropathology and Applied Neurobiology. 40: 778-82. PMID 24750115 DOI: 10.1111/nan.12144  0.52
2014 Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EH. A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases. Journal of Neuropathology and Experimental Neurology. 73: 467-73. PMID 24709683 DOI: 10.1097/NEN.0000000000000070  0.52
2014 Mesulam MM, Weintraub S, Rogalski EJ, Wieneke C, Geula C, Bigio EH. Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia. Brain : a Journal of Neurology. 137: 1176-92. PMID 24574501 DOI: 10.1093/brain/awu024  0.52
2014 Riascos D, Nicholas A, Samaeekia R, Yukhananov R, Mesulam MM, Bigio EH, Weintraub S, Guo L, Geula C. Alterations of Ca²⁺-responsive proteins within cholinergic neurons in aging and Alzheimer's disease. Neurobiology of Aging. 35: 1325-33. PMID 24461366 DOI: 10.1016/j.neurobiolaging.2013.12.017  0.52
2014 van Blitterswijk M, Mullen B, Nicholson AM, Bieniek KF, Heckman MG, Baker MC, DeJesus-Hernandez M, Finch NA, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, ... Bigio EH, et al. TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia. Acta Neuropathologica. 127: 397-406. PMID 24385136 DOI: 10.1007/s00401-013-1240-4  0.52
2013 van Blitterswijk M, Baker MC, DeJesus-Hernandez M, Ghidoni R, Benussi L, Finger E, Hsiung GY, Kelley BJ, Murray ME, Rutherford NJ, Brown PE, Ravenscroft T, Mullen B, Ash PE, Bieniek KF, ... ... Bigio EH, et al. C9ORF72 repeat expansions in cases with previously identified pathogenic mutations. Neurology. 81: 1332-41. PMID 24027057 DOI: 10.1212/WNL.0b013e3182a8250c  0.52
2013 Ahmed Z, Bigio EH, Budka H, Dickson DW, Ferrer I, Ghetti B, Giaccone G, Hatanpaa KJ, Holton JL, Josephs KA, Powers J, Spina S, Takahashi H, White CL, Revesz T, et al. Globular glial tauopathies (GGT): consensus recommendations. Acta Neuropathologica. 126: 537-44. PMID 23995422 DOI: 10.1007/s00401-013-1171-0  0.52
2013 Rayaprolu S, Mullen B, Baker M, Lynch T, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, Josephs KA, Knopman DS, White CL, Caselli R, et al. TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease. Molecular Neurodegeneration. 8: 19. PMID 23800361 DOI: 10.1186/1750-1326-8-19  0.52
2013 Pressman P, Bigio EH, Gitelman D, Zadikoff C. Clinical Reasoning: a woman with rapidly progressive apraxia. Neurology. 80: e162-5. PMID 23569002 DOI: 10.1212/WNL.0b013e31828c2eb8  0.52
2013 Bigio EH, Wu JY, Deng HX, Bit-Ivan EN, Mao Q, Ganti R, Peterson M, Siddique N, Geula C, Siddique T, Mesulam M. Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid. Acta Neuropathologica. 125: 463-5. PMID 23378033 DOI: 10.1007/s00401-013-1089-6  0.52
2013 Lee KH, Lall RR, Chandler JP, Bigio EH, Mao Q. Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: case report and literature review. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 33: 192-8. PMID 22784446 DOI: 10.1111/j.1440-1789.2012.01337.x  0.48
2013 Bigio EH, Weintraub S, Rademakers R, Baker M, Ahmadian SS, Rademaker A, Weitner BB, Mao Q, Lee KH, Mishra M, Ganti RA, Mesulam MM. Frontotemporal lobar degeneration with TDP-43 proteinopathy and chromosome 9p repeat expansion in C9ORF72: clinicopathologic correlation. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 33: 122-33. PMID 22702520 DOI: 10.1111/j.1440-1789.2012.01332.x  0.52
2013 Davidson YS, Robinson AC, Hu Q, Mishra M, Baborie A, Jaros E, Perry RH, Cairns NJ, Richardson A, Gerhard A, Neary D, Snowden JS, Bigio EH, Mann DM. Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes. Neuropathology and Applied Neurobiology. 39: 157-65. PMID 22497712 DOI: 10.1111/j.1365-2990.2012.01274.x  0.52
2012 Rutherford NJ, Heckman MG, Dejesus-Hernandez M, Baker MC, Soto-Ortolaza AI, Rayaprolu S, Stewart H, Finger E, Volkening K, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, Lippa C, et al. Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype. Neurobiology of Aging. 33: 2950.e5-7. PMID 22840558 DOI: 10.1016/j.neurobiolaging.2012.07.005  0.52
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Bigio EH, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/hmg/dds161  0.52
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/NEN.0b013e31825018f7  0.52
2012 Nakamura K, Greenwood A, Binder L, Bigio EH, Denial S, Nicholson L, Zhou XZ, Lu KP. Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease. Cell. 149: 232-44. PMID 22464332 DOI: 10.1016/j.cell.2012.02.016  0.52
2012 Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 1-13. PMID 22265587 DOI: 10.1016/j.jalz.2011.10.007  0.52
2012 Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathologica. 123: 1-11. PMID 22101365 DOI: 10.1007/s00401-011-0910-3  0.52
2011 Deng HX, Bigio EH, Siddique T. Detection of protein aggregation in neurodegenerative diseases. Methods in Molecular Biology (Clifton, N.J.). 793: 259-72. PMID 21913106 DOI: 10.1007/978-1-61779-328-8_17  0.52
2011 Deng HX, Chen W, Hong ST, Boycott KM, Gorrie GH, Siddique N, Yang Y, Fecto F, Shi Y, Zhai H, Jiang H, Hirano M, Rampersaud E, Jansen GH, Donkervoort S, ... Bigio EH, et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature. 477: 211-5. PMID 21857683 DOI: 10.1038/nature10353  0.52
2011 Deng HX, Bigio EH, Zhai H, Fecto F, Ajroud K, Shi Y, Yan J, Mishra M, Ajroud-Driss S, Heller S, Sufit R, Siddique N, Mugnaini E, Siddique T. Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations. Archives of Neurology. 68: 1057-61. PMID 21825243 DOI: 10.1001/archneurol.2011.178  0.52
2011 Armstrong RA, Gearing M, Bigio EH, Cruz-Sanchez FF, Duyckaerts C, Mackenzie IR, Perry RH, Skullerud K, Yokoo H, Cairns NJ. Spatial patterns of FUS-immunoreactive neuronal cytoplasmic inclusions (NCI) in neuronal intermediate filament inclusion disease (NIFID). Journal of Neural Transmission (Vienna, Austria : 1996). 118: 1651-7. PMID 21792670 DOI: 10.1007/s00702-011-0690-x  0.52
2011 Chen Y, Yang M, Deng J, Chen X, Ye Y, Zhu L, Liu J, Ye H, Shen Y, Li Y, Rao EJ, Fushimi K, Zhou X, Bigio EH, Mesulam M, et al. Expression of human FUS protein in Drosophila leads to progressive neurodegeneration. Protein & Cell. 2: 477-86. PMID 21748598 DOI: 10.1007/s13238-011-1065-7  0.52
2011 Guo W, Chen Y, Zhou X, Kar A, Ray P, Chen X, Rao EJ, Yang M, Ye H, Zhu L, Liu J, Xu M, Yang Y, Wang C, Zhang D, ... Bigio EH, et al. An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nature Structural & Molecular Biology. 18: 822-30. PMID 21666678 DOI: 10.1038/nsmb.2053  0.52
2011 Ross OA, Rutherford NJ, Baker M, Soto-Ortolaza AI, Carrasquillo MM, DeJesus-Hernandez M, Adamson J, Li M, Volkening K, Finger E, Seeley WW, Hatanpaa KJ, Lomen-Hoerth C, Kertesz A, Bigio EH, et al. Ataxin-2 repeat-length variation and neurodegeneration. Human Molecular Genetics. 20: 3207-12. PMID 21610160 DOI: 10.1093/hmg/ddr227  0.52
2011 Page T, Gitcho MA, Mosaheb S, Carter D, Chakraverty S, Perry RH, Bigio EH, Gearing M, Ferrer I, Goate AM, Cairns NJ, Thorpe JR. FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy. Journal of Molecular Neuroscience : Mn. 45: 409-21. PMID 21603978 DOI: 10.1007/s12031-011-9549-8  0.52
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Bigio EH, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/ng.801  0.52
2011 Ferreira A, Bigio EH. Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathies. Molecular Medicine (Cambridge, Mass.). 17: 676-85. PMID 21442128 DOI: 10.2119/molmed.2010.00220  0.52
2011 Finch N, Carrasquillo MM, Baker M, Rutherford NJ, Coppola G, Dejesus-Hernandez M, Crook R, Hunter T, Ghidoni R, Benussi L, Crook J, Finger E, Hantanpaa KJ, Karydas AM, Sengdy P, ... ... Bigio EH, et al. TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers. Neurology. 76: 467-74. PMID 21178100 DOI: 10.1212/WNL.0b013e31820a0e3b  0.52
2011 Armstrong RA, Gearing M, Bigio EH, Cruz-Sanchez FF, Duyckaerts C, Mackenzie IR, Perry RH, Skullerud K, Yokoo H, Cairns NJ. The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease. Acta Neuropathologica. 121: 219-28. PMID 20886222 DOI: 10.1007/s00401-010-0753-3  0.52
2011 Dequen F, Cairns NJ, Bigio EH, Julien JP. Gigaxonin mutation analysis in patients with NIFID. Neurobiology of Aging. 32: 1528-9. PMID 19782434 DOI: 10.1016/j.neurobiolaging.2009.08.018  0.52
2010 Deng HX, Zhai H, Bigio EH, Yan J, Fecto F, Ajroud K, Mishra M, Ajroud-Driss S, Heller S, Sufit R, Siddique N, Mugnaini E, Siddique T. FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis. Annals of Neurology. 67: 739-48. PMID 20517935 DOI: 10.1002/ana.22051  0.52
2010 Urwin H, Josephs KA, Rohrer JD, Mackenzie IR, Neumann M, Authier A, Seelaar H, Van Swieten JC, Brown JM, Johannsen P, Nielsen JE, Holm IE, Dickson DW, Rademakers R, ... ... Bigio EH, et al. FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathologica. 120: 33-41. PMID 20490813 DOI: 10.1007/s00401-010-0698-6  0.52
2010 Gliebus G, Bigio EH, Gasho K, Mishra M, Caplan D, Mesulam MM, Geula C. Asymmetric TDP-43 distribution in primary progressive aphasia with progranulin mutation. Neurology. 74: 1607-10. PMID 20479359 DOI: 10.1212/WNL.0b013e3181df0a1b  0.52
2010 Perry A, Burton SS, Fuller GN, Robinson CA, Palmer CA, Resch L, Bigio EH, Gujrati M, Rosenblum MK. Oligodendroglial neoplasms with ganglioglioma-like maturation: a diagnostic pitfall. Acta Neuropathologica. 120: 237-52. PMID 20464403 DOI: 10.1007/s00401-010-0695-9  0.52
2010 Bigio EH, Mishra M, Hatanpaa KJ, White CL, Johnson N, Rademaker A, Weitner BB, Deng HX, Dubner SD, Weintraub S, Mesulam M. TDP-43 pathology in primary progressive aphasia and frontotemporal dementia with pathologic Alzheimer disease. Acta Neuropathologica. 120: 43-54. PMID 20361198 DOI: 10.1007/s00401-010-0681-2  0.52
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Bigio EH, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/ng.536  0.52
2009 Foulds PG, Davidson Y, Mishra M, Hobson DJ, Humphreys KM, Taylor M, Johnson N, Weintraub S, Akiyama H, Arai T, Hasegawa M, Bigio EH, Benson FE, Allsop D, Mann DM. Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathologica. 118: 647-58. PMID 19823856 DOI: 10.1007/s00401-009-0594-0  0.52
2009 Gitcho MA, Bigio EH, Mishra M, Johnson N, Weintraub S, Mesulam M, Rademakers R, Chakraverty S, Cruchaga C, Morris JC, Goate AM, Cairns NJ. TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy. Acta Neuropathologica. 118: 633-45. PMID 19618195 DOI: 10.1007/s00401-009-0571-7  0.52
2008 Schaffer BA, Bertram L, Miller BL, Mullin K, Weintraub S, Johnson N, Bigio EH, Mesulam M, Wiedau-Pazos M, Jackson GR, Cummings JL, Cantor RM, Levey AI, Tanzi RE, Geschwind DH. Association of GSK3B with Alzheimer disease and frontotemporal dementia. Archives of Neurology. 65: 1368-74. PMID 18852354 DOI: 10.1001/archneur.65.10.1368  0.52
2008 Rutherford NJ, Zhang YJ, Baker M, Gass JM, Finch NA, Xu YF, Stewart H, Kelley BJ, Kuntz K, Crook RJ, Sreedharan J, Vance C, Sorenson E, Lippa C, Bigio EH, et al. Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. Plos Genetics. 4: e1000193. PMID 18802454 DOI: 10.1371/journal.pgen.1000193  0.52
2008 Mesulam M, Wicklund A, Johnson N, Rogalski E, Léger GC, Rademaker A, Weintraub S, Bigio EH. Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia. Annals of Neurology. 63: 709-19. PMID 18412267 DOI: 10.1002/ana.21388  0.52
2008 Hatanpaa KJ, Bigio EH, Cairns NJ, Womack KB, Weintraub S, Morris JC, Foong C, Xiao G, Hladik C, Mantanona TY, White CL. TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study. Journal of Neuropathology and Experimental Neurology. 67: 271-9. PMID 18379440 DOI: 10.1097/NEN.0b013e31816a12a6  0.52
2008 Gitcho MA, Baloh RH, Chakraverty S, Mayo K, Norton JB, Levitch D, Hatanpaa KJ, White CL, Bigio EH, Caselli R, Baker M, Al-Lozi MT, Morris JC, Pestronk A, Rademakers R, et al. TDP-43 A315T mutation in familial motor neuron disease. Annals of Neurology. 63: 535-8. PMID 18288693 DOI: 10.1002/ana.21344  0.52
2008 Mukherjee O, Wang J, Gitcho M, Chakraverty S, Taylor-Reinwald L, Shears S, Kauwe JS, Norton J, Levitch D, Bigio EH, Hatanpaa KJ, White CL, Morris JC, Cairns NJ, Goate A. Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia. Human Mutation. 29: 512-21. PMID 18183624 DOI: 10.1002/humu.20681  0.64
2008 De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL. Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers. Neurobiology of Aging. 29: 1334-47. PMID 17403556 DOI: 10.1016/j.neurobiolaging.2007.02.029  0.52
2007 Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, ... ... Bigio EH, et al. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. The Lancet. Neurology. 6: 857-68. PMID 17826340 DOI: 10.1016/S1474-4422(07)70221-1  0.52
2007 Cairns NJ, Neumann M, Bigio EH, Holm IE, Troost D, Hatanpaa KJ, Foong C, White CL, Schneider JA, Kretzschmar HA, Carter D, Taylor-Reinwald L, Paulsmeyer K, Strider J, Gitcho M, et al. TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. The American Journal of Pathology. 171: 227-40. PMID 17591968 DOI: 10.2353/ajpath.2007.070182  0.52
2007 Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, et al. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathologica. 114: 5-22. PMID 17579875 DOI: 10.1007/s00401-007-0237-2  0.52
2007 Mishra M, Paunesku T, Woloschak GE, Siddique T, Zhu LJ, Lin S, Greco K, Bigio EH. Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions. Acta Neuropathologica. 114: 81-94. PMID 17569064 DOI: 10.1007/s00401-007-0240-7  0.52
2007 Davion S, Johnson N, Weintraub S, Mesulam MM, Engberg A, Mishra M, Baker M, Adamson J, Hutton M, Rademakers R, Bigio EH. Clinicopathologic correlation in PGRN mutations. Neurology. 69: 1113-21. PMID 17522386 DOI: 10.1212/01.wnl.0000267701.58488.69  0.52
2007 Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Annals of Neurology. 61: 427-34. PMID 17469116 DOI: 10.1002/ana.21147  0.52
2007 Melquist S, Craig DW, Huentelman MJ, Crook R, Pearson JV, Baker M, Zismann VL, Gass J, Adamson J, Szelinger S, Corneveaux J, Cannon A, Coon KD, Lincoln S, Adler C, ... ... Bigio EH, et al. Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms. American Journal of Human Genetics. 80: 769-78. PMID 17357082 DOI: 10.1086/513320  0.52
2007 Mesulam M, Johnson N, Krefft TA, Gass JM, Cannon AD, Adamson JL, Bigio EH, Weintraub S, Dickson DW, Hutton ML, Graff-Radford NR. Progranulin mutations in primary progressive aphasia: the PPA1 and PPA3 families. Archives of Neurology. 64: 43-7. PMID 17210807 DOI: 10.1001/archneur.64.1.43  0.52
2007 Lambert MP, Velasco PT, Chang L, Viola KL, Fernandez S, Lacor PN, Khuon D, Gong Y, Bigio EH, Shaw P, De Felice FG, Krafft GA, Klein WL. Monoclonal antibodies that target pathological assemblies of Abeta. Journal of Neurochemistry. 100: 23-35. PMID 17116235 DOI: 10.1111/j.1471-4159.2006.04157.x  0.52
2006 Reynolds MR, Reyes JF, Fu Y, Bigio EH, Guillozet-Bongaarts AL, Berry RW, Binder LI. Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10636-45. PMID 17050703 DOI: 10.1523/JNEUROSCI.2143-06.2006  0.52
2006 Shiarli AM, Jennings R, Shi J, Bailey K, Davidson Y, Tian J, Bigio EH, Ghetti B, Murrell JR, Delisle MB, Mirra S, Crain B, Zolo P, Arima K, Iseki E, et al. Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease. Neuropathology and Applied Neurobiology. 32: 374-87. PMID 16866983 DOI: 10.1111/j.1365-2990.2006.00736.x  0.52
2006 Bonte FJ, Harris TS, Hynan LS, Bigio EH, White CL. Tc-99m HMPAO SPECT in the differential diagnosis of the dementias with histopathologic confirmation. Clinical Nuclear Medicine. 31: 376-8. PMID 16785801 DOI: 10.1097/01.rlu.0000222736.81365.63  0.52
2006 Deng HX, Shi Y, Furukawa Y, Zhai H, Fu R, Liu E, Gorrie GH, Khan MS, Hung WY, Bigio EH, Lukas T, Dal Canto MC, O'Halloran TV, Siddique T. Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 103: 7142-7. PMID 16636275 DOI: 10.1073/pnas.0602046103  0.52
2006 de Silva R, Lashley T, Strand C, Shiarli AM, Shi J, Tian J, Bailey KL, Davies P, Bigio EH, Arima K, Iseki E, Murayama S, Kretzschmar H, Neumann M, Lippa C, et al. An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathologica. 111: 329-40. PMID 16552612 DOI: 10.1007/s00401-006-0048-x  0.52
2006 Momeni P, Cairns NJ, Perry RH, Bigio EH, Gearing M, Singleton AB, Hardy J. Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID). Neurobiology of Aging. 27: 778.e1-778.e6. PMID 16005115 DOI: 10.1016/j.neurobiolaging.2005.03.030  0.52
2004 Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10191-200. PMID 15537891 DOI: 10.1523/JNEUROSCI.3432-04.2004  0.52
2004 Cairns NJ, Grossman M, Arnold SE, Burn DJ, Jaros E, Perry RH, Duyckaerts C, Stankoff B, Pillon B, Skullerud K, Cruz-Sanchez FF, Bigio EH, Mackenzie IR, Gearing M, Juncos JL, et al. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Neurology. 63: 1376-84. PMID 15505152  0.52
2004 Berry RW, Sweet AP, Clark FA, Lagalwar S, Lapin BR, Wang T, Topgi S, Guillozet-Bongaarts AL, Cochran EJ, Bigio EH, Binder LI. Tau epitope display in progressive supranuclear palsy and corticobasal degeneration. Journal of Neurocytology. 33: 287-95. PMID 15475684 DOI: 10.1023/B:NEUR.0000044190.96426.b9  0.52
2004 Lipton AM, White CL, Bigio EH. Frontotemporal lobar degeneration with motor neuron disease-type inclusions predominates in 76 cases of frontotemporal degeneration. Acta Neuropathologica. 108: 379-85. PMID 15351890 DOI: 10.1007/s00401-004-0900-9  0.64
2004 Bigio EH, Johnson NA, Rademaker AW, Fung BB, Mesulam MM, Siddique N, Dellefave L, Caliendo J, Freeman S, Siddique T. Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology. 63: 801-11. PMID 15330335  0.52
2004 Hatanpaa KJ, Blass DM, Pletnikova O, Crain BJ, Bigio EH, Hedreen JC, White CL, Troncoso JC. Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia. Neurology. 63: 538-42. PMID 15304590  0.64
2004 Lipton AM, Benavides R, Hynan LS, Bonte FJ, Harris TS, White CL, Bigio EH. Lateralization on neuroimaging does not differentiate frontotemporal lobar degeneration from Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 17: 324-7. PMID 15178946 DOI: 10.1159/000077164  0.52
2004 Cairns NJ, Uryu K, Bigio EH, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Arnold SE, Lee VM, Trojanowski JQ. alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases. Acta Neuropathologica. 108: 213-23. PMID 15170578 DOI: 10.1007/s00401-004-0882-7  0.52
2003 Weiner MF, Hynan LS, Parikh B, Zaki N, White CL, Bigio EH, Lipton AM, Martin-Cook K, Svetlik DA, Cullum CM, Vobach S, Rosenberg RN. Can alzheimer's disease and dementias with Lewy bodies be distinguished clinically? Journal of Geriatric Psychiatry and Neurology. 16: 245-50. PMID 14653435 DOI: 10.1177/0891988703258671  0.52
2003 Hogg M, Grujic ZM, Baker M, Demirci S, Guillozet AL, Sweet AP, Herzog LL, Weintraub S, Mesulam MM, LaPointe NE, Gamblin TC, Berry RW, Binder LI, de Silva R, Lees A, ... ... Bigio EH, et al. The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy. Acta Neuropathologica. 106: 323-36. PMID 12883828 DOI: 10.1007/s00401-003-0734-x  0.52
2003 Strong MJ, Lomen-Hoerth C, Caselli RJ, Bigio EH, Yang W. Cognitive impairment, frontotemporal dementia, and the motor neuron diseases. Annals of Neurology. 54: S20-3. PMID 12833364 DOI: 10.1002/ana.10574  0.52
2003 Bigio EH, Lipton AM, White CL, Dickson DW, Hirano A. Frontotemporal and motor neurone degeneration with neurofilament inclusion bodies: additional evidence for overlap between FTD and ALS. Neuropathology and Applied Neurobiology. 29: 239-53. PMID 12787321  0.64
2003 Bigio EH, Reisch JS, White CL, Satumtira S, Sontag E, Bonte FJ. Synapse loss may be a minor contributor to decreased regional cerebral blood flow in Alzheimer disease. Dementia and Geriatric Cognitive Disorders. 15: 72-8. PMID 12566595  0.64
2002 Morris HR, Baker M, Yasojima K, Houlden H, Khan MN, Wood NW, Hardy J, Grossman M, Trojanowski J, Revesz T, Bigio EH, Bergeron C, Janssen JC, McGeer PL, Rossor MN, et al. Analysis of tau haplotypes in Pick's disease. Neurology. 59: 443-5. PMID 12177383  0.52
2002 Bigio EH, Hynan LS, Sontag E, Satumtira S, White CL. Synapse loss is greater in presenile than senile onset Alzheimer disease: implications for the cognitive reserve hypothesis. Neuropathology and Applied Neurobiology. 28: 218-27. PMID 12060346  0.64
2001 Lipton AM, Cullum CM, Satumtira S, Sontag E, Hynan LS, White CL, Bigio EH. Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias. Archives of Neurology. 58: 1233-9. PMID 11493163  0.64
2001 Bonte FJ, Weiner MF, Bigio EH, White CL. SPECT imaging in dementias. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 42: 1131-3. PMID 11438640  0.52
2001 Houlden H, Baker M, Morris HR, MacDonald N, Pickering-Brown S, Adamson J, Lees AJ, Rossor MN, Quinn NP, Kertesz A, Khan MN, Hardy J, Lantos PL, St George-Hyslop P, Munoz DG, ... ... Bigio EH, et al. Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. Neurology. 56: 1702-6. PMID 11425937  0.52
2001 Bigio EH, Vono MB, Satumtira S, Adamson J, Sontag E, Hynan LS, White CL, Baker M, Hutton M. Cortical synapse loss in progressive supranuclear palsy. Journal of Neuropathology and Experimental Neurology. 60: 403-10. PMID 11379815  0.52
2001 Bigio EH, Lipton AM, Yen SH, Hutton ML, Baker M, Nacharaju P, White CL, Davies P, Lin W, Dickson DW. Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia. Journal of Neuropathology and Experimental Neurology. 60: 328-41. PMID 11305868  0.64
2000 Honig LS, Chambliss DD, Bigio EH, Carroll SL, Elliott JL. Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls. Neurology. 55: 1082-8. PMID 11071482  0.52
1999 Bigio EH, Colvin SM, Mickey BE, White CL, Rushing EJ. Radiation change versus recurrent astrocytoma: diagnostic utility of the proliferation index? Journal of Neuro-Oncology. 41: 55-63. PMID 10222423 DOI: 10.1023/A:1006112228001  0.52
1999 Bigio EH, Brown DF, White CL. Progressive supranuclear palsy with dementia: cortical pathology. Journal of Neuropathology and Experimental Neurology. 58: 359-64. PMID 10218631  0.64
1998 Amato AA, Kagan-Hallet K, Jackson CE, Lampkin S, Wolfe GI, Ferrante M, Bigio EH, Barohn RJ. The wide spectrum of myofibrillar myopathy suggests a multifactorial etiology and pathogenesis. Neurology. 51: 1646-55. PMID 9855517  0.52
1998 Barnea A, Aguila-Mansilla N, Bigio EH, Worby C, Roberts J. Evidence for regulated expression of neuropeptide Y gene by rat and human cultured astrocytes. Regulatory Peptides. 75: 293-300. PMID 9802422 DOI: 10.1016/S0167-0115(98)00081-0  0.52
1998 Brown DF, Risser RC, Bigio EH, Tripp P, Stiegler A, Welch E, Eagan KP, Hladik CL, White CL. Neocortical synapse density and Braak stage in the Lewy body variant of Alzheimer disease: a comparison with classic Alzheimer disease and normal aging. Journal of Neuropathology and Experimental Neurology. 57: 955-60. PMID 9786245  0.52
1998 Brown DF, Dababo MA, Bigio EH, Risser RC, Eagan KP, Hladik CL, White CL. Neuropathologic evidence that the Lewy body variant of Alzheimer disease represents coexistence of Alzheimer disease and idiopathic Parkinson disease. Journal of Neuropathology and Experimental Neurology. 57: 39-46. PMID 9600196  0.52
1998 Rushing EJ, White JA, D' Alise MD, Chason DP, White CL, Bigio EH. Primary epithelioid hemangioendothelioma of the clivus. Clinical Neuropathology. 17: 110-4. PMID 9561333  0.64
1998 Bigio EH, Fontaine CS, Dababo MA, Prahlow JA, Chason DP, Weiner MF, White CL. Dementia associated with cortical dysplasia. Acta Neuropathologica. 95: 193-8. PMID 9498056 DOI: 10.1007/s004010050786  0.52
1997 Rushing EJ, Barnard JJ, Bigio EH, Eagan KP, White CL. Frequency of unilateral and bilateral mesial temporal sclerosis in primary and secondary epilepsy: a forensic autopsy study. The American Journal of Forensic Medicine and Pathology. 18: 335-41. PMID 9430283 DOI: 10.1097/00000433-199712000-00004  0.52
1997 Bigio EH, Weiner MF, Bonte FJ, White CL. Familial dementia due to adult polyglucosan body disease. Clinical Neuropathology. 16: 227-34. PMID 9266150  0.52
1997 Bonte FJ, Weiner MF, Bigio EH, White CL. Brain blood flow in the dementias: SPECT with histopathologic correlation in 54 patients. Radiology. 202: 793-7. PMID 9051035 DOI: 10.1148/radiology.202.3.9051035  0.52
1994 Pardue S, White CL, Bigio EH, Morrison-Bogorad M. Anomalous binding of radiolabeled oligonucleotide probes to plaques and tangles in Alzheimer disease hippocampus. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 22: 1-24. PMID 7916765  0.64
1993 Bonte FJ, Tintner R, Weiner MF, Bigio EH, White CL. Brain blood flow in the dementias: SPECT with histopathologic correlation. Radiology. 186: 361-5. PMID 8421735 DOI: 10.1148/radiology.186.2.8421735  0.52
1991 Sparkman DR, Bigio EH, White CL. Neuropathologic examination of rabbit brain after long-term immunization with Alzheimer paired helical filaments. Alzheimer Disease and Associated Disorders. 5: 194-6. PMID 1772640  0.52
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