| Year |
Citation |
Score |
| 2012 |
Ramos A, Garrison V, Koop D, Rooney W, Bourdette D, Lovera J. Polyphenon E, a Green Tea Extract, Increases Brain NAA Levels in MS: A Pilot Six Month Open Label Study (P03.050) Neurology. 78: P03.050-P03.050. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P03.050 |
0.316 |
|
| 2011 |
Wang Y, Guan S, Acharya P, Koop DR, Liu Y, Liao M, Burlingame AL, Correia MA. Ubiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitination. The Journal of Biological Chemistry. 286: 9443-56. PMID 21209460 DOI: 10.1074/Jbc.M110.176685 |
0.333 |
|
| 2011 |
Bradford BU, Lock EF, Kosyk O, Kim S, Uehara T, Harbourt D, DeSimone M, Threadgill DW, Tryndyak V, Pogribny IP, Bleyle L, Koop DR, Rusyn I. Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 206-17. PMID 21135412 DOI: 10.1093/Toxsci/Kfq362 |
0.315 |
|
| 2008 |
McDougall SJ, Peters JH, LaBrant L, Wang X, Koop DR, Andresen MC. Paired assessment of volatile anesthetic concentrations with synaptic actions recorded in vitro. Plos One. 3: e3372. PMID 18841202 DOI: 10.1371/Journal.Pone.0003372 |
0.531 |
|
| 2008 |
Peters JH, McDougall SJ, Mendelowitz D, Koop DR, Andresen MC. Isoflurane differentially modulates inhibitory and excitatory synaptic transmission to the solitary tract nucleus. Anesthesiology. 108: 675-83. PMID 18362600 DOI: 10.1097/Aln.0B013E318167Af9A |
0.528 |
|
| 2005 |
Lakshman R, Cederbaum AI, Hoek JB, Konishi M, Koop D, Donohu TM. Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol. Alcoholism, Clinical and Experimental Research. 29: 1726-34. PMID 16205373 DOI: 10.1097/01.Alc.0000179379.03078.8F |
0.338 |
|
| 2005 |
Bradford BU, Kono H, Isayama F, Kosyk O, Wheeler MD, Akiyama TE, Bleye L, Krausz KW, Gonzalez FJ, Koop DR, Rusyn I. Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver. Hepatology (Baltimore, Md.). 41: 336-44. PMID 15660387 DOI: 10.1002/Hep.20532 |
0.333 |
|
| 2004 |
Huan JY, Streicher JM, Bleyle LA, Koop DR. Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells. Toxicology and Applied Pharmacology. 199: 332-43. PMID 15364548 DOI: 10.1016/J.Taap.2003.12.019 |
0.362 |
|
| 2004 |
DeBarber AE, Bleyle LA, Roullet JB, Koop DR. Omega-hydroxylation of farnesol by mammalian cytochromes p450. Biochimica Et Biophysica Acta. 1682: 18-27. PMID 15158752 DOI: 10.1016/J.Bbalip.2004.01.003 |
0.389 |
|
| 2004 |
Schattenberg JM, Wang Y, Rigoli RM, Koop DR, Czaja MJ. CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling. Hepatology (Baltimore, Md.). 39: 444-55. PMID 14767997 DOI: 10.1002/Hep.20067 |
0.308 |
|
| 2003 |
Isayama F, Froh M, Bradford BU, McKim SE, Kadiiska MB, Connor HD, Mason RP, Koop DR, Wheeler MD, Arteel GE. The CYP inhibitor 1-aminobenzotriazole does not prevent oxidative stress associated with alcohol-induced liver injury in rats and mice. Free Radical Biology & Medicine. 35: 1568-81. PMID 14680680 DOI: 10.1016/J.Freeradbiomed.2003.09.007 |
0.36 |
|
| 2003 |
Wadsworth T, Poonyagariyagorn H, Sullivan E, Koop D, Roselli CE. In vivo effect of PC-SPES on prostate growth and hepatic CYP3A expression in rats. The Journal of Pharmacology and Experimental Therapeutics. 306: 187-94. PMID 12676889 DOI: 10.1124/Jpet.102.048645 |
0.305 |
|
| 2003 |
Spatzenegger M, Liu H, Wang Q, Debarber A, Koop DR, Halpert JR. Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling. The Journal of Pharmacology and Experimental Therapeutics. 304: 477-87. PMID 12490624 DOI: 10.1124/Jpet.102.043323 |
0.317 |
|
| 2002 |
Jones BE, Liu H, Lo CR, Koop DR, Czaja MJ. Cytochrome P450 2E1 expression induces hepatocyte resistance to cell death from oxidative stress. Antioxidants & Redox Signaling. 4: 701-9. PMID 12470497 DOI: 10.1089/152308602760598846 |
0.338 |
|
| 2001 |
Rivera CA, Bradford BU, Hunt KJ, Adachi Y, Schrum LW, Koop DR, Burchardt ER, Rippe RA, Thurman RG. Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G200-7. PMID 11408273 DOI: 10.1152/Ajpgi.2001.281.1.G200 |
0.317 |
|
| 1999 |
Kono H, Bradford BU, Yin M, Sulik KK, Koop DR, Peters JM, Gonzalez FJ, McDonald T, Dikalova A, Kadiiska MB, Mason RP, Thurman RG. CYP2E1 is not involved in early alcohol-induced liver injury. The American Journal of Physiology. 277: G1259-67. PMID 10600824 DOI: 10.1152/Ajpgi.1999.277.6.G1259 |
0.324 |
|
| 1998 |
Jin R, Koop DR, Raucy JL, Lasker JM. Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4. Archives of Biochemistry and Biophysics. 359: 89-98. PMID 9799565 DOI: 10.1006/Abbi.1998.0880 |
0.398 |
|
| 1998 |
Nieusma JL, Claffey DJ, Koop DR, Chen W, Peter RM, Nelson SD, Ruth JA, Ross D. Oxidation of 1,3-butadiene to (R)- and (S)-butadiene monoxide by purified recombinant cytochrome P450 2E1 from rabbit, rat and human. Toxicology Letters. 95: 123-9. PMID 9635416 DOI: 10.1016/S0378-4274(98)00026-5 |
0.33 |
|
| 1998 |
Guan X, Fisher MB, Lang DH, Zheng YM, Koop DR, Rettie AE. Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid. Chemico-Biological Interactions. 110: 103-21. PMID 9566728 DOI: 10.1016/S0009-2797(97)00145-2 |
0.371 |
|
| 1997 |
Helvig C, Alayrac C, Mioskowski C, Koop D, Poullain D, Durst F, Salaün JP. Suicide inactivation of cytochrome P450 by midchain and terminal acetylenes. A mechanistic study of inactivation of a plant lauric acid omega-hydroxylase. The Journal of Biological Chemistry. 272: 414-21. PMID 8995277 DOI: 10.1074/Jbc.272.1.414 |
0.39 |
|
| 1995 |
Barmada S, Kienle E, Koop DR. Rabbit P450 2E1 expressed in CHO-K1 cells has a short half-life. Biochemical and Biophysical Research Communications. 206: 601-7. PMID 7826377 DOI: 10.1006/Bbrc.1995.1085 |
0.307 |
|
| 1994 |
Howard PC, McManus ME, Koop DR. The role of cytochrome P450 2C3 in rabbit liver microsomal metabolism of 1-nitropyrene and 3-nitrofluoranthene. Journal of Biochemical Toxicology. 9: 71-8. PMID 8071948 DOI: 10.1002/Jbt.2570090204 |
0.383 |
|
| 1994 |
Laethem RM, Halpert JR, Koop DR. Epoxidation of arachidonic acid as an active-site probe of cytochrome P-450 2B isoforms. Biochimica Et Biophysica Acta. 1206: 42-8. PMID 7910485 DOI: 10.1016/0167-4838(94)90070-1 |
0.315 |
|
| 1993 |
Kedderis GL, Batra R, Koop DR. Epoxidation of acrylonitrile by rat and human cytochromes P450. Chemical Research in Toxicology. 6: 866-71. PMID 8117926 DOI: 10.1021/Tx00036A017 |
0.39 |
|
| 1992 |
Koop DR. Oxidative and reductive metabolism by cytochrome P450 2E1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 724-30. PMID 1537462 DOI: 10.1096/Fasebj.6.2.1537462 |
0.386 |
|
| 1992 |
Castillo T, Koop DR, Kamimura S, Triadafilopoulos G, Tsukamoto H. Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation. Hepatology (Baltimore, Md.). 16: 992-6. PMID 1398507 DOI: 10.1002/Hep.1840160423 |
0.37 |
|
| 1992 |
Tierney DJ, Haas AL, Koop DR. Degradation of cytochrome P450 2E1: selective loss after labilization of the enzyme. Archives of Biochemistry and Biophysics. 293: 9-16. PMID 1309987 DOI: 10.1016/0003-9861(92)90358-4 |
0.364 |
|
| 1991 |
Koop DR, Laethem RM, Goldner AL, Douglas JG. Cytochrome P450 expression and metabolism in isolated rabbit renal epithelium. Methods in Enzymology. 206: 364-71. PMID 1784223 DOI: 10.1016/0076-6879(91)06106-D |
0.339 |
|
| 1990 |
Koop DR, Tierney DJ. Multiple mechanisms in the regulation of ethanol-inducible cytochrome P450IIE1. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 12: 429-35. PMID 2256907 DOI: 10.1002/Bies.950120906 |
0.349 |
|
| 1990 |
Koop DR. Inhibition of ethanol-inducible cytochrome P450IIE1 by 3-amino-1,2,4-triazole. Chemical Research in Toxicology. 3: 377-83. PMID 2133088 DOI: 10.1021/Tx00016A017 |
0.399 |
|
| 1989 |
Sinclair JF, Wood SG, Smith EL, Sinclair PR, Koop DR. Comparison of the form(s) of cytochrome P-450 induced by ethanol and glutethimide in cultured chick hepatocytes. Biochemical Pharmacology. 38: 657-64. PMID 2917020 DOI: 10.1016/0006-2952(89)90212-8 |
0.402 |
|
| 1989 |
Hoffman J, Konopka K, Buckhorn C, Koop DR, Waskell L. Ethanol-inducible cytochrome P450 in rabbits metabolizes enflurane. British Journal of Anaesthesia. 63: 103-8. PMID 2765333 DOI: 10.1093/Bja/63.1.103 |
0.405 |
|
| 1989 |
Koop DR, Laethem CL, Schnier GG. Identification of ethanol-inducible P450 isozyme 3a (P450IIE1) as a benzene and phenol hydroxylase. Toxicology and Applied Pharmacology. 98: 278-88. PMID 2711391 DOI: 10.1016/0041-008X(89)90233-0 |
0.348 |
|
| 1989 |
McCoy GD, DeMarco GJ, Koop DR. Microsomal nicotine metabolism: a comparison of relative activities of six purified rabbit cytochrome P-450 isozymes. Biochemical Pharmacology. 38: 1185-8. PMID 2706016 DOI: 10.1016/0006-2952(89)90267-0 |
0.338 |
|
| 1989 |
Koop DR, Laethem CL, Tierney DJ. The utility of p-nitrophenol hydroxylation in P450IIE1 analysis. Drug Metabolism Reviews. 20: 541-51. PMID 2680397 DOI: 10.3109/03602538909103560 |
0.331 |
|
| 1988 |
Handler JA, Koop DR, Coon MJ, Takei Y, Thurman RG. Identification of P-450ALC in microsomes from alcohol dehydrogenase-deficient deermice: contribution to ethanol elimination in vivo. Archives of Biochemistry and Biophysics. 264: 114-24. PMID 3395117 DOI: 10.1016/0003-9861(88)90576-0 |
0.353 |
|
| 1988 |
McCoy GD, Koop DR. Biochemical and immunochemical evidence for the induction of an ethanol-inducible cytochrome P-450 isozyme in male Syrian golden hamsters. Biochemical Pharmacology. 37: 1563-8. PMID 3358786 DOI: 10.1016/0006-2952(88)90019-6 |
0.405 |
|
| 1987 |
Raucy J, Fernandes P, Black M, Yang SL, Koop DR. Identification of a human liver cytochrome P-450 exhibiting catalytic and immunochemical similarities to cytochrome P-450 3a of rabbit liver. Biochemical Pharmacology. 36: 2921-6. PMID 3632717 DOI: 10.1016/0006-2952(87)90203-6 |
0.408 |
|
| 1987 |
Coon MJ, Koop DR. Alcohol-inducible cytochrome P-450 (P-450ALC). Archives of Toxicology. 60: 16-21. PMID 3304205 DOI: 10.1007/Bf00296940 |
0.385 |
|
| 1987 |
Khani SC, Zaphiropoulos PG, Fujita VS, Porter TD, Koop DR, Coon MJ. cDNA and derived amino acid sequence of ethanol-inducible rabbit liver cytochrome P-450 isozyme 3a (P-450ALC). Proceedings of the National Academy of Sciences of the United States of America. 84: 638-42. PMID 3027695 DOI: 10.1073/Pnas.84.3.638 |
0.374 |
|
| 1986 |
Koop DR, Coon MJ. Ethanol oxidation and toxicity: role of alcohol P-450 oxygenase. Alcoholism, Clinical and Experimental Research. 10: 44S-49S. PMID 3544930 DOI: 10.1111/J.1530-0277.1986.Tb05179.X |
0.407 |
|
| 1986 |
Ryan DE, Koop DR, Thomas PE, Coon MJ, Levin W. Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a. Archives of Biochemistry and Biophysics. 246: 633-44. PMID 3518633 DOI: 10.1016/0003-9861(86)90319-X |
0.419 |
|
| 1985 |
Koop DR, Coon MJ. Role of alcohol P-450-oxygenase (APO) in microsomal ethanol oxidation. Alcohol (Fayetteville, N.Y.). 2: 23-6. PMID 4015835 DOI: 10.1016/0741-8329(85)90008-4 |
0.408 |
|
| 1985 |
Yang CS, Koop DR, Wang TY, Coon MJ. Immunochemical studies on the metabolism of nitrosamines by ethanol-inducible cytochrome P-450. Biochemical and Biophysical Research Communications. 128: 1007-13. PMID 3994708 DOI: 10.1016/0006-291X(85)90147-0 |
0.432 |
|
| 1985 |
Yang CS, Tu YY, Koop DR, Coon MJ. Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes. Cancer Research. 45: 1140-5. PMID 3971365 |
0.321 |
|
| 1985 |
Holm KA, Koop DR, Coon MJ, Theoharides AD, Kupfer D. omega-1 and omega-2 hydroxylation of prostaglandins by rabbit hepatic microsomal cytochrome P-450 isozyme 6. Archives of Biochemistry and Biophysics. 243: 135-43. PMID 3864395 DOI: 10.1016/0003-9861(85)90781-7 |
0.412 |
|
| 1985 |
Koop DR, Crump BL, Nordblom GD, Coon MJ. Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid. Proceedings of the National Academy of Sciences of the United States of America. 82: 4065-9. PMID 3858864 DOI: 10.1073/Pnas.82.12.4065 |
0.407 |
|
| 1984 |
Coon MJ, Koop DR, Reeve LE, Crump BL. Alcohol metabolism and toxicity: role of cytochrome P-450. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: 134-43. PMID 6724188 DOI: 10.1016/0272-0590(84)90113-1 |
0.429 |
|
| 1984 |
Fujita VS, Black SD, Tarr GE, Koop DR, Coon MJ. On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit liver microsomes. Proceedings of the National Academy of Sciences of the United States of America. 81: 4260-4. PMID 6589592 DOI: 10.1073/Pnas.81.14.4260 |
0.347 |
|
| 1984 |
Koop DR, Nordblom GD, Coon MJ. Immunochemical evidence for a role of cytochrome P-450 in liver microsomal ethanol oxidation. Archives of Biochemistry and Biophysics. 235: 228-38. PMID 6497392 DOI: 10.1016/0003-9861(84)90272-8 |
0.407 |
|
| 1984 |
Thomas PE, Reidy J, Reik LM, Ryan DE, Koop DR, Levin W. Use of monoclonal antibody probes against rat hepatic cytochromes P-450c and P-450d to detect immunochemically related isozymes in liver microsomes from different species. Archives of Biochemistry and Biophysics. 235: 239-53. PMID 6208847 DOI: 10.1016/0003-9861(84)90273-X |
0.371 |
|
| 1983 |
Morgan ET, Koop DR, Coon MJ. Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen. Biochemical and Biophysical Research Communications. 112: 8-13. PMID 6838622 DOI: 10.1016/0006-291X(83)91789-8 |
0.425 |
|
| 1983 |
Coon MJ, Koop DR, Morgan ET. Alcohol oxidation by isozyme 3a of liver microsomal cytochrome P-450. Pharmacology, Biochemistry, and Behavior. 18: 177-80. PMID 6685296 DOI: 10.1016/0091-3057(83)90168-5 |
0.391 |
|
| 1983 |
Coon MJ, Koop DR. 19 P-450 Oxygenases in Lipid Transformation Enzymes. 16: 645-677. DOI: 10.1016/S1874-6047(08)60317-0 |
0.386 |
|
| 1982 |
Delaforge M, Koop DR, Coon MJ. Role of isosafrole as complexing agent and inducer of P-450LM4 in rabbit liver microsomes. Biochemical and Biophysical Research Communications. 108: 59-65. PMID 6816232 DOI: 10.1016/0006-291X(82)91831-9 |
0.399 |
|
| 1979 |
Koop DR, Coon MJ. Purification and properties of P-450LM3b, a constitutive form of cytochrome P-450, from rabbit liver microsomes. Biochemical and Biophysical Research Communications. 91: 1075-81. PMID 526267 DOI: 10.1016/0006-291X(79)91990-9 |
0.392 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2010 |
Powell CL, Bradford BU, Craig CP, Tsuchiya M, Uehara T, O'Connell TM, Pogribny IP, Melnyk S, Koop DR, Bleyle L, Threadgill DW, Rusyn I. Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 131-9. PMID 20118189 DOI: 10.1093/Toxsci/Kfq031 |
0.296 |
|
| 1999 |
Haining RL, Jones JP, Henne KR, Fisher MB, Koop DR, Trager WF, Rettie AE. Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding. Biochemistry. 38: 3285-92. PMID 10079071 DOI: 10.1021/Bi982161+ |
0.295 |
|
| 1985 |
Kokkinakis DM, Koop DR, Scarpelli DG, Coon MJ, Hollenberg PF. Metabolism of N-nitroso-2,6-dimethylmorpholine by isozymes of rabbit liver microsomal cytochrome P-450. Cancer Research. 45: 619-24. PMID 3967237 |
0.293 |
|
| 1981 |
Huang MT, Johnson EF, Muller-Eberhard U, Koop DR, Coon MJ, Conney AH. Specificity in the activation and inhibition by flavonoids of benzo[a]pyrene hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes. The Journal of Biological Chemistry. 256: 10897-901. PMID 6270135 |
0.292 |
|
| 2003 |
Micu AL, Miksys S, Sellers EM, Koop DR, Tyndale RF. Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism. The Journal of Pharmacology and Experimental Therapeutics. 306: 941-7. PMID 12750430 DOI: 10.1124/Jpet.103.052183 |
0.292 |
|
| 2008 |
Zhang W, Otsuka T, Sugo N, Ardeshiri A, Alhadid YK, Iliff JJ, DeBarber AE, Koop DR, Alkayed NJ. Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 39: 2073-8. PMID 18369166 DOI: 10.1161/Strokeaha.107.508325 |
0.288 |
|
| 1988 |
Gruenke LD, Konopka K, Koop DR, Waskell LA. Characterization of halothane oxidation by hepatic microsomes and purified cytochromes P-450 using a gas chromatographic mass spectrometric assay. The Journal of Pharmacology and Experimental Therapeutics. 246: 454-9. PMID 3404442 |
0.287 |
|
| 2001 |
Wadsworth TL, Koop DR. Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced release of nitric oxide. Chemico-Biological Interactions. 137: 43-58. PMID 11518563 DOI: 10.1016/S0009-2797(01)00208-3 |
0.286 |
|
| 2011 |
O'Hare T, Eide CA, Adrian LT, Agarwal A, Zabriskie MS, MacKenzie R, LaTocha DH, You H, Luo J, Riddle SM, Marks B, Koop DR, Apgar J, Deininger MW, Druker BJ. Cryptic Intracellular Retention of ABL Tyrosine Kinase Inhibitors within CML Cells Mediates Apoptosis Commitment Following Acute Drug Exposure, Blood. 118: 3504-3504. DOI: 10.1182/Blood.V118.21.3504.3504 |
0.28 |
|
| 2005 |
Soumyanath A, Zhong YP, Gold SA, Yu X, Koop DR, Bourdette D, Gold BG. Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro. The Journal of Pharmacy and Pharmacology. 57: 1221-9. PMID 16105244 DOI: 10.1211/Jpp.57.9.0018 |
0.278 |
|
| 2011 |
Winter R, Kelly JX, Smilkstein MJ, Hinrichs D, Koop DR, Riscoe MK. Optimization of endochin-like quinolones for antimalarial activity. Experimental Parasitology. 127: 545-51. PMID 21040724 DOI: 10.1016/J.Exppara.2010.10.016 |
0.278 |
|
| 2017 |
Asquith M, Davin S, Stauffer P, Michell C, Janowitz C, Lin P, Ensign-Lewis J, Kinchen JM, Koop DR, Rosenbaum J. Intestinal metabolites are profoundly altered in the context of HLA-B27 expression and functionally modulate disease in a rat model of spondyloarthropathy. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28622455 DOI: 10.1002/Art.40183 |
0.278 |
|
| 2007 |
Koerner IP, Jacks R, DeBarber AE, Koop D, Mao P, Grant DF, Alkayed NJ. Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4642-9. PMID 17460077 DOI: 10.1097/00008506-200610000-00099 |
0.275 |
|
| 1982 |
Koop DR, Morgan ET, Tarr GE, Coon MJ. Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits. The Journal of Biological Chemistry. 257: 8472-80. PMID 7085677 |
0.273 |
|
| 1982 |
Morgan ET, Koop DR, Coon MJ. Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols. The Journal of Biological Chemistry. 257: 13951-7. PMID 7142188 |
0.273 |
|
| 2019 |
Shinto L, Lahna D, Dodge HH, Hagen K, Koop D, Quinn JF, Kaye JA, Silbert LC. P2-025: Products From Soluble Epoxide Hydrolase Derived Omega-6 And Omega-3 Oxylipins Are Associated With Increased White Matter Hyperintensity And Poorer Performance On Trails-B In A Cohort Of Cognitively Normal, Hypertensive Young-Old Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.1247 |
0.268 |
|
| 2011 |
Jones JP, Joswig-Jones CA, Hebner M, Chu Y, Koop DR. The effects of nitrogen-heme-iron coordination on substrate affinities for cytochrome P450 2E1. Chemico-Biological Interactions. 193: 50-6. PMID 21600194 DOI: 10.1016/J.Cbi.2011.05.001 |
0.266 |
|
| 2010 |
Yadav V, Marracci GH, Munar MY, Cherala G, Stuber LE, Alvarez L, Shinto L, Koop DR, Bourdette DN. Pharmacokinetic study of lipoic acid in multiple sclerosis: comparing mice and human pharmacokinetic parameters. Multiple Sclerosis (Houndmills, Basingstoke, England). 16: 387-97. PMID 20150394 DOI: 10.1177/1352458509359722 |
0.265 |
|
| 2012 |
Salinthone S, Yadav V, Ganesh M, Cherala G, Shinto L, Koop D, Bourdette D, Carr D. P02.183. Comparing the bioavailability of two forms of lipoic acid in multiple sclerosis Bmc Complementary and Alternative Medicine. 12. DOI: 10.1186/1472-6882-12-S1-P239 |
0.264 |
|
| 2013 |
O'Hare T, Eide CA, Agarwal A, Adrian LT, Zabriskie MS, Mackenzie RJ, Latocha DH, Johnson KJ, You H, Luo J, Riddle SM, Marks BD, Vogel KW, Koop DR, Apgar J, et al. Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells determine their commitment to apoptosis. Cancer Research. 73: 3356-70. PMID 23576564 DOI: 10.1158/0008-5472.Can-12-3904 |
0.262 |
|
| 2001 |
Wadsworth TL, McDonald TL, Koop DR. Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha. Biochemical Pharmacology. 62: 963-74. PMID 11543732 DOI: 10.1016/S0006-2952(01)00734-1 |
0.261 |
|
| 1986 |
Koop DR. Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Molecular Pharmacology. 29: 399-404. PMID 3702859 |
0.26 |
|
| 1999 |
Wadsworth TL, Koop DR. Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages. Biochemical Pharmacology. 57: 941-9. PMID 10086329 DOI: 10.1016/S0006-2952(99)00002-7 |
0.255 |
|
| 2013 |
Alumkal JJ, Slottke R, Mori M, Schwartzman J, Graff JN, Beer TM, Ryan CW, Koop DR, Cherala G, Munar M, Flamiatos JF, Gao L, Tucker E. Sulforaphane treatment in men with recurrent prostate cancer. Journal of Clinical Oncology. 31: 5017-5017. DOI: 10.1200/Jco.2013.31.15_Suppl.5017 |
0.254 |
|
| 2005 |
Koerner IP, Zhang W, Hurn PD, Koop D, Alkayed NJ. Soluble epoxide hydrolase gene deletion reduces inflammation after stroke Journal of Cerebral Blood Flow & Metabolism. 25: S93-S93. DOI: 10.1038/Sj.Jcbfm.9591524.0093 |
0.254 |
|
| 2005 |
Deng QG, She H, Cheng JH, French SW, Koop DR, Xiong S, Tsukamoto H. Steatohepatitis induced by intragastric overfeeding in mice. Hepatology (Baltimore, Md.). 42: 905-14. PMID 16175602 DOI: 10.1002/Hep.20877 |
0.253 |
|
| 1992 |
Koop DR, Laethem CL. Inhibition of rabbit microsomal cytochrome P-450 2E1-dependent p-nitrophenol hydroxylation by substituted benzene derivatives. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 20: 775-7. PMID 1358586 |
0.253 |
|
| 1999 |
Downes H, Koop DR, Klopfenstein B, Lessov N. Retention of nociceptor responses during deep barbiturate anesthesia in frogs. Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 124: 203-10. PMID 10622437 DOI: 10.1016/S0742-8413(99)00069-9 |
0.252 |
|
| 1997 |
Koop DR, Klopfenstein B, Iimuro Y, Thurman RG. Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1. Molecular Pharmacology. 51: 944-50. PMID 9187260 DOI: 10.1124/Mol.51.6.944 |
0.251 |
|
| 1988 |
Howard PC, Reed KA, Koop DR. Oxidative metabolism of 1-nitropyrene by rabbit liver microsomes and purified microsomal cytochrome P-450 isozymes. Cancer Research. 48: 4261-5. PMID 3390822 |
0.25 |
|
| 1984 |
Koop DR, Coon MJ. Purification of liver microsomal cytochrome P-450 isozymes 3a and 6 from imidazole-treated rabbits. Evidence for the identity of isozyme 3a with the form obtained by ethanol treatment. Molecular Pharmacology. 25: 494-501. PMID 6427601 |
0.25 |
|
| 2016 |
Foss MH, Pou S, Davidson PM, Dunaj JL, Winter RW, Pou S, Licon MH, Doh JK, Li Y, Kelly JX, Dodean RA, Koop DR, Riscoe MK, Purdy GE. Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis. Acs Infectious Diseases. 2: 500-508. PMID 27626102 DOI: 10.1021/Acsinfecdis.6B00052 |
0.249 |
|
| 1989 |
Clejan LA, Koop DR, Cederbaum AI. Sensitivity of the rat liver microsomal oxidation of pyrazole to antibody raised against the ethanol-inducible rabbit liver cytochrome P-450 isozyme. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 17: 694-8. PMID 2575510 |
0.249 |
|
| 2013 |
Koop DR, Bleyle LA, Munar M, Cherala G, Al-Uzri A. Analysis of tacrolimus and creatinine from a single dried blood spot using liquid chromatography tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 926: 54-61. PMID 23548676 DOI: 10.1016/J.Jchromb.2013.02.035 |
0.246 |
|
| 2019 |
Smilkstein MJ, Pou S, Krollenbrock A, Bleyle LA, Dodean RA, Frueh L, Hinrichs DJ, Li Y, Martinson T, Munar MY, Winter RW, Bruzual I, Whiteside S, Nilsen A, Koop DR, et al. ELQ-331 as a prototype for extremely durable chemoprotection against malaria. Malaria Journal. 18: 291. PMID 31455339 DOI: 10.1186/S12936-019-2921-9 |
0.245 |
|
| 1990 |
Tierney DJ, Koop DR. Rapid proteolysis of CCI4-inactivated P450IIE1 is accompanied by ubiquitin conjugation Free Radical Biology and Medicine. 9: 83. DOI: 10.1016/0891-5849(90)90463-S |
0.244 |
|
| 1981 |
Koop DR, Persson AV, Coon MJ. Properties of electrophoretically homogeneous constitutive forms of liver microsomal cytochrome P-450. The Journal of Biological Chemistry. 256: 10704-11. PMID 7287730 |
0.237 |
|
| 2016 |
Welker KM, Lassetter B, Brandes CM, Prasad S, Koop DR, Mehta PH. A comparison of salivary testosterone measurement using immunoassays and tandem mass spectrometry. Psychoneuroendocrinology. 71: 180-188. PMID 27295182 DOI: 10.1016/J.Psyneuen.2016.05.022 |
0.235 |
|
| 1997 |
Sewer MB, Koop DR, Morgan ET. Differential inductive and suppressive effects of endotoxin and particulate irritants on hepatic and renal cytochrome P-450 expression. The Journal of Pharmacology and Experimental Therapeutics. 280: 1445-54. PMID 9067334 |
0.23 |
|
| 2012 |
Edelman A, Munar M, Elman MR, Koop D, Cherala G. Effect of the ethinylestradiol/levonorgestrel combined oral contraceptive on the activity of cytochrome P4503A in obese women. British Journal of Clinical Pharmacology. 74: 510-4. PMID 22299599 DOI: 10.1111/J.1365-2125.2012.04209.X |
0.229 |
|
| 2012 |
Wallisch M, El Rody NM, Huang B, Koop DR, Baker JR, Olsen GD. Naloxone pro-drug rescues morphine induced respiratory depression in Sprague-Dawley rats. Respiratory Physiology & Neurobiology. 180: 52-60. PMID 22027217 DOI: 10.1016/J.Resp.2011.10.009 |
0.228 |
|
| 1985 |
Koop DR, Casazza JP. Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes. The Journal of Biological Chemistry. 260: 13607-12. PMID 4055750 |
0.228 |
|
| 2017 |
Bittner F, Murchison C, Koop D, Bourdette D, Spain R. Lipoic Acid Pharmacokinetics at Baseline and 1 year in Secondary Progressive MS. Neuroimmunology and Neuroinflammation. 4: 380. PMID 28680918 DOI: 10.1212/Nxi.0000000000000380 |
0.227 |
|
| 1998 |
Brunner LJ, Bennett WM, Koop DR. Cyclosporine suppresses rat hepatic cytochrome P450 in a time-dependent manner. Kidney International. 54: 216-23. PMID 9648082 DOI: 10.1046/j.1523-1755.1998.00970.x |
0.225 |
|
| 2005 |
Yang MD, Deng QG, Chen S, Xiong S, Koop D, Tsukamoto H. Hepatoprotective mechanisms of Yan-gan-wan. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 32: 202-12. PMID 16107322 DOI: 10.1016/J.Hepres.2005.06.004 |
0.225 |
|
| 2005 |
Blanke CD, Mattek NC, Deloughery TG, Koop DR. A phase I study of 5-fluorouracil, leucovorin, and celecoxib in patients with incurable colorectal cancer. Prostaglandins & Other Lipid Mediators. 75: 169-72. PMID 15789623 DOI: 10.1016/J.Prostaglandins.2004.10.004 |
0.224 |
|
| 2015 |
Lovera J, Ramos A, Devier D, Garrison V, Kovner B, Reza T, Koop D, Rooney W, Foundas A, Bourdette D. Polyphenon E, non-futile at neuroprotection in multiple sclerosis but unpredictably hepatotoxic: Phase I single group and phase II randomized placebo-controlled studies. Journal of the Neurological Sciences. 358: 46-52. PMID 26298797 DOI: 10.1016/J.Jns.2015.08.006 |
0.22 |
|
| 1986 |
Ding XX, Koop DR, Crump BL, Coon MJ. Immunochemical identification of cytochrome P-450 isozyme 3a (P-450ALC) in rabbit nasal and kidney microsomes and evidence for differential induction by alcohol. Molecular Pharmacology. 30: 370-8. PMID 3762523 |
0.217 |
|
| 1980 |
Koop DR, Hollenberg PF. Kinetics of the hydroperoxide-dependent dealkylation reactions catalyzed by rabbit liver microsomal cytochrome P-450. The Journal of Biological Chemistry. 255: 9685-92. PMID 7430093 |
0.217 |
|
| 2017 |
Al-Uzri A, Freeman KA, Wade J, Clark K, Bleyle LA, Munar M, Koop DR. Longitudinal study on the use of dried blood spots for home monitoring in children after kidney transplantation. Pediatric Transplantation. PMID 28635157 DOI: 10.1111/Petr.12983 |
0.212 |
|
| 1984 |
Gorsky LD, Koop DR, Coon MJ. On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction. The Journal of Biological Chemistry. 259: 6812-7. PMID 6725272 |
0.208 |
|
| 2006 |
Lycette JL, Dul CL, Munar M, Belle D, Chui SY, Koop DR, Nichols CR. Effect of pregnancy on the pharmacokinetics of paclitaxel: a case report. Clinical Breast Cancer. 7: 342-4. PMID 17092404 DOI: 10.3816/Cbc.2006.N.049 |
0.207 |
|
| 1991 |
Koop DR, Chernosky A, Brass EP. Identification and induction of cytochrome P450 2E1 in rat Kupffer cells. The Journal of Pharmacology and Experimental Therapeutics. 258: 1072-6. PMID 1890612 |
0.205 |
|
| 2015 |
Alumkal JJ, Slottke R, Schwartzman J, Cherala G, Munar M, Graff JN, Beer TM, Ryan CW, Koop DR, Gibbs A, Gao L, Flamiatos JF, Tucker E, Kleinschmidt R, Mori M. A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer. Investigational New Drugs. 33: 480-9. PMID 25431127 DOI: 10.1007/S10637-014-0189-Z |
0.204 |
|
| 2006 |
Koop DR. Alcohol metabolism's damaging effects on the cell: a focus on reactive oxygen generation by the enzyme cytochrome P450 2E1. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 29: 274-80. PMID 17718406 |
0.204 |
|
| 1992 |
Laethem RM, Laethem CL, Ding X, Koop DR. P-450-dependent arachidonic acid metabolism in rabbit olfactory microsomes. The Journal of Pharmacology and Experimental Therapeutics. 262: 433-8. PMID 1625211 |
0.197 |
|
| 2014 |
Freeman K, Clark K, Garg B, Koop D, Munar M, Al-Uzri A. Itʼs in the Blood: Association Between Completion of Dried Blood Spot Monitoring and Medication Adherence and Patient Preference. Transplantation. 98: 497. DOI: 10.1097/00007890-201407151-01658 |
0.192 |
|
| 1994 |
Daikh BE, Laethem RM, Koop DR. Stereoselective epoxidation of arachidonic acid by cytochrome P-450s 2CAA and 2C2. The Journal of Pharmacology and Experimental Therapeutics. 269: 1130-5. PMID 8014857 |
0.191 |
|
| 2014 |
Al-Uzri A, Munar M, Freeman K, Iragorri S, Jenkins R, Rozansky D, Koop D. Novel Use of Dried Blood Spots for Home Monitoring in Children After Kidney Transplanation. Transplantation. 98: 500. DOI: 10.1097/00007890-201407151-01669 |
0.191 |
|
| 1996 |
Sewer MB, Koop DR, Morgan ET. Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 24: 401-7. PMID 8801054 |
0.187 |
|
| 1988 |
Coon MJ, Koop DR. Answer 1 to Rao Et Al. Alcoholism: Clinical and Experimental Research. 12: 300-301. DOI: 10.1111/J.1530-0277.1988.Tb00200.X |
0.168 |
|
| 1980 |
Koop DR, Hollenberg PF. Liver microsomal metabolism of N-methylcarbazole: a probe for induction, inhibition, and species differences. Molecular Pharmacology. 17: 118-27. PMID 7383014 |
0.165 |
|
| 1994 |
Daikh BE, Lasker JM, Raucy JL, Koop DR. Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9. The Journal of Pharmacology and Experimental Therapeutics. 271: 1427-33. PMID 7996455 |
0.157 |
|
| 1992 |
Laethem RM, Koop DR. Identification of rabbit cytochromes P450 2C1 and 2C2 as arachidonic acid epoxygenases. Molecular Pharmacology. 42: 958-63. PMID 1480136 |
0.156 |
|
| 1993 |
Thibonnier M, Bayer AL, Laethem CL, Koop DR, Simonson MS. Role of eicosanoids in vasopressin-induced calcium mobilization in A7r5 vascular smooth muscle cells. The American Journal of Physiology. 265: E108-14. PMID 8338143 |
0.152 |
|
| 1993 |
Laethem RM, Balazy M, Falck JR, Laethem CL, Koop DR. Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1. The Journal of Biological Chemistry. 268: 12912-8. PMID 8509425 |
0.15 |
|
| 1992 |
Laethem RM, Laethem CL, Koop DR. Purification and properties of a cytochrome P450 arachidonic acid epoxygenase from rabbit renal cortex. The Journal of Biological Chemistry. 267: 5552-9. PMID 1544930 |
0.14 |
|
| 1996 |
Brunner LJ, Bennett WM, Koop DR. Selective suppression of rat hepatic microsomal activity during chronic cyclosporine nephrotoxicity. The Journal of Pharmacology and Experimental Therapeutics. 277: 1710-8. PMID 8667242 |
0.131 |
|
| 1989 |
Schnier GG, Laethem CL, Koop DR. Identification and induction of cytochromes P450, P450IIE1 and P450IA1 in rabbit bone marrow. The Journal of Pharmacology and Experimental Therapeutics. 251: 790-6. PMID 2509684 |
0.128 |
|
| 2011 |
Edelman A, Cherala G, Koop D, Munar M, Jensen J, Stanczyk F. Cytochrome P450 phenotyping to estimate contraceptive steroid hormone metabolism — a pilot study in obese women Contraception. 84: 318-319. DOI: 10.1016/J.Contraception.2011.05.064 |
0.122 |
|
| 2016 |
Martin JL, Yates PA, Boitz JM, Koop DR, Fulwiler AL, Cassera MB, Ullman B, Carter NS. A Role for Adenine Nucleotides in the Sensing Mechanism to Purine Starvation in Leishmania donovani. Molecular Microbiology. PMID 27062185 DOI: 10.1111/mmi.13390 |
0.121 |
|
| 1980 |
Novak RF, Koop DR, Hollenberg PF. Liver microsomal metabolism of N-methylcarbazole: structural identification of the four major metabolites of N-methylcarbazole using 1H Fourier transform NMR spectroscopy. Molecular Pharmacology. 17: 128-36. PMID 7383015 |
0.116 |
|
| 1988 |
McCoy GD, Koop DR. Reconstitution of rabbit liver microsomal N-nitrosopyrrolidine alpha-hydroxylase activity. Cancer Research. 48: 3987-92. PMID 3383193 |
0.116 |
|
| 1996 |
Laethem RM, Balazy M, Koop DR. Epoxidation of C18 unsaturated fatty acids by cytochromes P4502C2 and P4502CAA. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 24: 664-8. PMID 8781783 |
0.094 |
|
| 2022 |
Togioka BM, Zarnegarnia Y, Bleyle LA, Koop D, Brookfield K, Yanez ND, Treggiari MM. Pharmacokinetics a>nd Tolerability of Intraperitoneal Chloroprocaine After Fetal Extraction in Women Undergoing Cesarean Delivery. Anesthesia and Analgesia. PMID 35544759 DOI: 10.1213/ANE.0000000000006064 |
0.092 |
|
| 2020 |
Cameron M, Taylor C, Lapidus J, Ramsey K, Koop D, Spain R. Gastrointestinal Tolerability and Absorption of R- Versus R,S-Lipoic Acid in Progressive Multiple Sclerosis: A Randomized Crossover Trial. Journal of Clinical Pharmacology. PMID 32212340 DOI: 10.1002/jcph.1605 |
0.09 |
|
| 1999 |
Huan JY, Koop DR. Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 27: 549-54. PMID 10101151 |
0.075 |
|
| 1980 |
Kedderis GL, Koop DR, Hollenberg PF. N-Demethylation reactions catalyzed by chloroperoxidase. The Journal of Biological Chemistry. 255: 10174-82. PMID 7191853 |
0.035 |
|
| 2021 |
Moss MJ, Bushlin I, Kazmierczak S, Koop D, Hendrickson RG, Zuckerman KE, Grigsby TM. Cannabis use and measurement of cannabinoids in plasma and breast milk of breastfeeding mothers. Pediatric Research. PMID 33469174 DOI: 10.1038/s41390-020-01332-2 |
0.021 |
|
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