| Year |
Citation |
Score |
| 2023 |
Yoon C, Lu J, Jun Y, Suh YS, Kim BJ, Till JE, Kim JH, Keshavjee SH, Ryeom S, Yoon SS. KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis. Bmc Cancer. 23: 690. PMID 37481516 DOI: 10.1186/s12885-023-11170-0 |
0.351 |
|
| 2021 |
Lu J, Cao LL, Xu Y, Huang XY, Cho SJ, Ashktorab H, Smoot DT, Li P, Zheng CH, Kim JW, Ryeom SW, Yoon SS, Yoon C, Huang CM. FOXC1 modulates stem-like cell properties and chemoresistance through Hedgehog and EMT signaling in gastric adenocarcinoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34534693 DOI: 10.1016/j.ymthe.2021.09.009 |
0.316 |
|
| 2021 |
Lu Z, Ortiz A, Verginadis II, Peck AR, Zahedi F, Cho C, Yu P, DeRita RM, Zhang H, Kubanoff R, Sun Y, Yaspan AT, Krespan E, Beiting DP, Radaelli E, ... Ryeom SW, et al. Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies. The Journal of Clinical Investigation. 131. PMID 33998600 DOI: 10.1172/JCI144225 |
0.37 |
|
| 2021 |
Yoon C, Lu J, Yi BC, Chang KK, Simon MC, Ryeom S, Yoon SS. PI3K/Akt pathway and Nanog maintain cancer stem cells in sarcomas. Oncogenesis. 10: 12. PMID 33468992 DOI: 10.1038/s41389-020-00300-z |
0.369 |
|
| 2021 |
Schmidt B, Lee HJ, Ryeom S, Yoon SS. Combining Bevacizumab with Radiation or Chemoradiation for Solid Tumors: A Review of the Scientific Rationale, and Clinical Trials. Current Angiogenesis. 1: 169-179. PMID 24977113 DOI: 10.2174/2211552811201030169 |
0.311 |
|
| 2020 |
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski KV, Alicea-Torres K, Li J, Todd L, Zhang H, Beiting DP, Sander C, Kirkwood JM, Snow BE, Wakeham AC, Mak TW, ... ... Ryeom SW, et al. Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs. Nature Cancer. 1: 603-619. PMID 34124690 DOI: 10.1038/s43018-020-0064-0 |
0.314 |
|
| 2020 |
Muramatsu M, Nakagawa S, Osawa T, Toyono T, Uemura A, Kidoya H, Takakura N, Usui T, Ryeom S, Minami T. Loss of Down Syndrome Critical Region-1 Mediated-Hypercholesterolemia Accelerates Corneal Opacity Via Pathological Neovessel Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315003. PMID 32787520 DOI: 10.1161/Atvbaha.120.315003 |
0.392 |
|
| 2020 |
Lin JX, Yoon C, Li P, Ryeom SW, Cho SJ, Zheng CH, Xie JW, Wang JB, Lu J, Chen QY, Yoon SS, Huang CM. CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer. British Journal of Cancer. PMID 32606358 DOI: 10.1038/S41416-020-0963-Y |
0.338 |
|
| 2019 |
Yoon C, Till J, Cho SJ, Chang KK, Lin JX, Huang CM, Ryeom S, Yoon SS. KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis. Molecular Cancer Research : McR. PMID 31217166 DOI: 10.1158/1541-7786.Mcr-19-0077 |
0.455 |
|
| 2019 |
Lieberman A, Barrett R, Kim J, Zhang KL, Avery D, Monslow J, Kim H, Kim BJ, Pure E, Ryeom S. Deletion of calcineurin promotes a pro-tumorigenic fibroblast phenotype. Cancer Research. PMID 31189649 DOI: 10.1158/0008-5472.Can-19-0056 |
0.431 |
|
| 2019 |
Kim YH, Oh MG, Bhang DH, Kim BJ, Jung SE, Kim SM, Dohr G, Kim SU, Ryeom S, Ryu BY. Testicular endothelial cells promote self-renewal of spermatogonial stem cells in rats. Biology of Reproduction. PMID 31187129 DOI: 10.1093/Biolre/Ioz105 |
0.308 |
|
| 2019 |
Yoon C, Till J, Cho S, Chang K, Lin J, Ryeom S, Yoon S. Abstract 4680: KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis Cancer Research. 79: 4680-4680. DOI: 10.1158/1538-7445.Sabcs18-4680 |
0.421 |
|
| 2018 |
Rowbotham SP, Li F, Dost AFM, Louie SM, Marsh BP, Pessina P, Anbarasu CR, Brainson CF, Tuminello SJ, Lieberman A, Ryeom S, Schlaeger TM, Aronow BJ, Watanabe H, Wong KK, et al. H3K9 methyltransferases and demethylases control lung tumor-propagating cells and lung cancer progression. Nature Communications. 9: 4559. PMID 30455465 DOI: 10.1038/S41467-018-07077-1 |
0.432 |
|
| 2018 |
Ryu MO, Kim BG, Choi US, Baek KH, Song YK, Li Q, Seo KW, Ryeom S, Youn HY, Bhang DH. Extracellular cyclic AMP-dependent protein kinase autoantibodies and C-reactive protein as serum biomarkers for diagnosis of cancer in dogs. Veterinary and Comparative Oncology. PMID 30411459 DOI: 10.1111/Vco.12450 |
0.369 |
|
| 2018 |
Bhang DH, Kim BJ, Kim BG, Schadler K, Baek KH, Kim YH, Hsiao W, Ding BS, Rafii S, Weiss MJ, Chou ST, Kolon TF, Ginsberg JP, Ryu BY, Ryeom S. Testicular endothelial cells are a critical population in the germline stem cell niche. Nature Communications. 9: 4379. PMID 30348976 DOI: 10.1038/S41467-018-06881-Z |
0.377 |
|
| 2018 |
Till J, Addai P, Bhagwat N, Yee S, Carpenter E, Yoon S, Ryeom S. Abstract 4077: A new mouse model of gastric adenocarcinoma: A valuable tool for preclinical studies Cancer Research. 78: 4077-4077. DOI: 10.1158/1538-7445.Am2018-4077 |
0.364 |
|
| 2017 |
Till J, Yoon C, Kim BJ, Roby KC, Addai P, Jonokuchi E, Tang LH, Yoon SS, Ryeom S. Oncogenic KRAS and p53 loss drive gastric tumorigenesis in mice that can be attenuated by E-cadherin expression. Cancer Research. PMID 28760854 DOI: 10.1158/0008-5472.Can-17-0061 |
0.396 |
|
| 2017 |
Yoon C, Cho SJ, Chang KK, Park DJ, Ryeom S, Yoon SS. Role of Rac1 pathway in epithelial-to-mesenchymal transition and cancer stem-like cell phenotypes in gastric adenocarcinoma. Molecular Cancer Research : McR. PMID 28461325 DOI: 10.1158/1541-7786.Mcr-17-0053 |
0.434 |
|
| 2017 |
Baek KH, Ryeom S. Detection of Oncogene-Induced Senescence In Vivo. Methods in Molecular Biology (Clifton, N.J.). 1534: 185-198. PMID 27812880 DOI: 10.1007/978-1-4939-6670-7_18 |
0.431 |
|
| 2017 |
Yoon C, Chang KK, Till J, Ryeom SW, Yoon SS. Abstract 2897: Oncogenic Kras activation in gastric adenocarcinoma promotes cancer stem cell phenotypes including metastasis & chemotherapy resistance Cancer Research. 77: 2897-2897. DOI: 10.1158/1538-7445.Am2017-2897 |
0.346 |
|
| 2016 |
Schadler KL, Thomas NJ, Galie PA, Bhang DH, Roby KC, Addai P, Till JE, Sturgeon K, Zaslavsky A, Chen CS, Ryeom S. Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy. Oncotarget. PMID 27589843 DOI: 10.18632/Oncotarget.11748 |
0.409 |
|
| 2016 |
Till J, Addai P, Yoon C, Kim B, Yoon S, Ryeom S. 782 A Tumor Suppressive Role for E-Cadherin in a New Model of Metastatic Gastric Cancer Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30637-0 |
0.373 |
|
| 2015 |
Lehman SL, Ryeom S, Koumenis C. Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma. Scientific Reports. 5: 11781. PMID 26123823 DOI: 10.1038/Srep11781 |
0.425 |
|
| 2015 |
Casey SC, Vaccari M, Al-Mulla F, Al-Temaimi R, Amedei A, Barcellos-Hoff MH, Brown DG, Chapellier M, Christopher J, Curran C, Forte S, Hamid RA, Heneberg P, Koch DC, Krishnakumar PK, ... ... Ryeom S, et al. The effect of environmental chemicals on the tumor microenvironment. Carcinogenesis. 36: S160-83. PMID 26106136 DOI: 10.1093/Carcin/Bgv035 |
0.444 |
|
| 2015 |
Zhou AY, Ryeom SW. Abstract A11: Cyclosporin A promotes tumor angiogenesis in a calcineurin-independent manner by increasing mitochondrial reactive oxygen species Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-A11 |
0.472 |
|
| 2014 |
Zhou AY, Ryeom SW. Cyclosporin A promotes tumor angiogenesis in a calcineurin-independent manner by increasing mitochondrial reactive oxygen species. Molecular Cancer Research. 12: 1663-1676. PMID 25009293 DOI: 10.1158/1541-7786.Mcr-14-0136 |
0.5 |
|
| 2014 |
Sturgeon K, Schadler K, Muthukumaran G, Ding D, Bajulaiye A, Thomas NJ, Ferrari V, Ryeom S, Libonati JR. Concomitant low-dose doxorubicin treatment and exercise. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R685-92. PMID 25009215 DOI: 10.1152/Ajpregu.00082.2014 |
0.312 |
|
| 2014 |
Schadler KL, Crosby EJ, Zhou AY, Bhang DH, Braunstein L, Baek KH, Crawford D, Crawford A, Angelosanto J, Wherry EJ, Ryeom S. Immunosurveillance by antiangiogenesis: tumor growth arrest by T cell-derived thrombospondin-1. Cancer Research. 74: 2171-81. PMID 24590059 DOI: 10.1158/0008-5472.Can-13-0094 |
0.443 |
|
| 2014 |
Lee JH, Bhang DH, Beede A, Huang TL, Stripp BR, Bloch KD, Wagers AJ, Tseng YH, Ryeom S, Kim CF. Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis. Cell. 156: 440-55. PMID 24485453 DOI: 10.1016/J.Cell.2013.12.039 |
0.369 |
|
| 2013 |
Baek KH, Bhang D, Zaslavsky A, Wang LC, Vachani A, Kim CF, Albelda SM, Evan GI, Ryeom S. Thrombospondin-1 mediates oncogenic Ras-induced senescence in premalignant lung tumors. The Journal of Clinical Investigation. 123: 4375-89. PMID 24018559 DOI: 10.1172/Jci67465 |
0.368 |
|
| 2013 |
Minami T, Jiang S, Schadler K, Suehiro JI, Osawa T, Oike Y, Miura M, Naito M, Kodama T, Ryeom S. The Calcineurin-NFAT-Angiopoietin-2 Signaling Axis in Lung Endothelium Is Critical for the Establishment of Lung Metastases Cell Reports. 4: 709-723. PMID 23954784 DOI: 10.1016/J.Celrep.2013.07.021 |
0.383 |
|
| 2013 |
Zaslavsky A, Chou ST, Schadler K, Lieberman A, Pimkin M, Kim YJ, Baek KH, Aird WC, Weiss MJ, Ryeom S. The calcineurin-NFAT pathway negatively regulates megakaryopoiesis. Blood. 121: 3205-15. PMID 23446734 DOI: 10.1182/Blood-2012-04-421172 |
0.385 |
|
| 2011 |
Becker CM, Beaudry P, Funakoshi T, Benny O, Zaslavsky A, Zurakowski D, Folkman J, D'Amato RJ, Ryeom S. Circulating endothelial progenitor cells are up-regulated in a mouse model of endometriosis. The American Journal of Pathology. 178: 1782-91. PMID 21435458 DOI: 10.1016/J.Ajpath.2010.12.037 |
0.376 |
|
| 2011 |
Ryeom SW. The cautionary tale of side effects of chronic Notch1 inhibition Journal of Clinical Investigation. 121: 508-509. PMID 21266769 DOI: 10.1172/Jci45976 |
0.354 |
|
| 2010 |
Rakhra K, Bachireddy P, Zabuawala T, Zeiser R, Xu L, Kopelman A, Fan AC, Yang Q, Braunstein L, Crosby E, Ryeom S, Felsher DW. CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation. Cancer Cell. 18: 485-98. PMID 21035406 DOI: 10.1016/J.Ccr.2010.10.002 |
0.405 |
|
| 2010 |
Lee YJ, Karl DL, Maduekwe UN, Rothrock C, Ryeom S, D'Amore PA, Yoon SS. Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment. Cancer Research. 70: 8357-67. PMID 20978198 DOI: 10.1158/0008-5472.Can-10-1138 |
0.441 |
|
| 2010 |
Zaslavsky A, Chen C, Grillo J, Baek KH, Holmgren L, Yoon SS, Folkman J, Ryeom S. Regional control of tumor growth. Molecular Cancer Research : McR. 8: 1198-206. PMID 20736295 DOI: 10.1158/1541-7786.Mcr-10-0047 |
0.429 |
|
| 2010 |
Lee MN, Lee SN, Kim SH, Kim B, Jung BK, Seo JH, Park JH, Choi JH, Yim SH, Lee MR, Park JG, Yoo JY, Kim JH, Lee ST, Kim HM, ... Ryeom S, et al. Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1alpha in tumor growth and metastasis. Journal of the National Cancer Institute. 102: 426-42. PMID 20194889 DOI: 10.1093/Jnci/Djq026 |
0.402 |
|
| 2010 |
Min J, Zaslavsky A, Fedele G, McLaughlin SK, Reczek EE, De Raedt T, Guney I, Strochlic DE, Macconaill LE, Beroukhim R, Bronson RT, Ryeom S, Hahn WC, Loda M, Cichowski K. An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB. Nature Medicine. 16: 286-94. PMID 20154697 DOI: 10.1038/Nm.2100 |
0.371 |
|
| 2010 |
Lee YJ, Koch M, Karl D, Torres-Collado AX, Fernando NT, Rothrock C, Kuruppu D, Ryeom S, Iruela-Arispe ML, Yoon SS. Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1. Cancer Research. 70: 948-56. PMID 20103648 DOI: 10.1158/0008-5472.Can-09-3094 |
0.39 |
|
| 2010 |
Zaslavsky A, Baek KH, Lynch RC, Short S, Grillo J, Folkman J, Italiano JE, Ryeom S. Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis. Blood. 115: 4605-13. PMID 20086246 DOI: 10.1182/Blood-2009-09-242065 |
0.455 |
|
| 2010 |
Karl DL, Lee YJ, Koch M, Torres-Collado AX, Fernando NT, Rothrock C, Kuruppu D, Ryeom S, Iruela-Arispe ML, Yoon SS. Abstract 2325: Thrombospondin 1 inhibits angiogenesis in liver metastases but not lung metastases due to differential cleavage activity of ADAMTS1 Cancer Research. 70: 2325-2325. DOI: 10.1158/1538-7445.Am10-2325 |
0.41 |
|
| 2009 |
Ryeom S, Folkman J. Role of endogenous angiogenesis inhibitors in Down syndrome. The Journal of Craniofacial Surgery. 20: 595-6. PMID 19795527 DOI: 10.1097/Scs.0B013E3181927F47 |
0.465 |
|
| 2009 |
Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T. The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice. The Journal of Clinical Investigation. 119: 2257-70. PMID 19620774 DOI: 10.1172/Jci35738 |
0.386 |
|
| 2009 |
Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, et al. Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. International Journal of Radiation Oncology, Biology, Physics. 74: 1207-16. PMID 19545786 DOI: 10.1016/J.Ijrobp.2009.02.052 |
0.312 |
|
| 2009 |
Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Folkman J, Daley GQ, Aird WC, Galdzicki Z, ... Ryeom S, et al. Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature. 459: 1126-30. PMID 19458618 DOI: 10.1038/Nature08062 |
0.384 |
|
| 2008 |
Ryeom S, Baek KH, Rioth MJ, Lynch RC, Zaslavsky A, Birsner A, Yoon SS, McKeon F. Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth. Cancer Cell. 13: 420-31. PMID 18455125 DOI: 10.1016/J.Ccr.2008.02.018 |
0.503 |
|
| 2008 |
Fernando NT, Koch M, Rothrock C, Gollogly LK, D'Amore PA, Ryeom S, Yoon SS. Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1529-39. PMID 18316578 DOI: 10.1158/1078-0432.Ccr-07-4126 |
0.432 |
|
| 2008 |
Beaudry P, Nilsson M, Rioth M, Prox D, Poon D, Xu L, Zweidler-Mckay P, Ryan A, Folkman J, Ryeom S, Heymach J. Potent antitumor effects of ZD6474 on neuroblastoma via dual targeting of tumor cells and tumor endothelium. Molecular Cancer Therapeutics. 7: 418-24. PMID 18245671 DOI: 10.1158/1535-7163.Mct-07-0568 |
0.486 |
|
| 2008 |
Johannessen CM, Johnson BW, Williams SM, Chan AW, Reczek EE, Lynch RC, Rioth MJ, McClatchey A, Ryeom S, Cichowski K. TORC1 is essential for NF1-associated malignancies. Current Biology : Cb. 18: 56-62. PMID 18164202 DOI: 10.1016/J.Cub.2007.11.066 |
0.43 |
|
| 2008 |
Italiano JE, Richardson JL, Patel-Hett S, Battinelli E, Zaslavsky A, Short S, Ryeom S, Folkman J, Klement GL. Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released. Blood. 111: 1227-33. PMID 17962514 DOI: 10.1182/Blood-2007-09-113837 |
0.348 |
|
| 2008 |
Maduekwe UN, Rothrock C, Ryeom S, Yoon SS, Lee Y. Differential effects of VEGF receptor inhibition in the liver and lung Journal of the American College of Surgeons. 207. DOI: 10.1016/J.Jamcollsurg.2008.06.254 |
0.331 |
|
| 2007 |
Beaudry P, Hida Y, Udagawa T, Alwayn IP, Greene AK, Arsenault D, Folkman J, Heymach JV, Ryeom S, Puder M. Endothelial progenitor cells contribute to accelerated liver regeneration. Journal of Pediatric Surgery. 42: 1190-8. PMID 17618879 DOI: 10.1016/J.Jpedsurg.2007.02.034 |
0.377 |
|
| 2007 |
Gollogly LK, Ryeom SW, Yoon SS. Down Syndrome Candidate Region 1-like 1 (DSCR1-L1) Mimics the Inhibitory Effects of DSCR1 on Calcineurin Signaling in Endothelial Cells and Inhibits Angiogenesis Journal of Surgical Research. 142: 129-136. PMID 17610901 DOI: 10.1016/J.Jss.2006.10.011 |
0.397 |
|
| 2006 |
Giuriato S, Ryeom S, Fan AC, Bachireddy P, Lynch RC, Rioth MJ, van Riggelen J, Kopelman AM, Passegué E, Tang F, Folkman J, Felsher DW. Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch. Proceedings of the National Academy of Sciences of the United States of America. 103: 16266-71. PMID 17056717 DOI: 10.1073/Pnas.0608017103 |
0.444 |
|
| 2006 |
Yoon SS, Segal NH, Park PJ, Detwiller KY, Fernando NT, Ryeom SW, Brennan MF, Singer S. Angiogenic profile of soft tissue sarcomas based on analysis of circulating factors and microarray gene expression. The Journal of Surgical Research. 135: 282-90. PMID 16603191 DOI: 10.1016/J.Jss.2006.01.023 |
0.326 |
|
| 2006 |
Gollogly LK, Ryeom SW, Detwiller KY, McKeon F, Yoon SS. Inhibition of VEGF-mediated calcineurin signaling by DSCR1 and DSCRL1 disrupts endothelial cell function and tumor angiogenesis Journal of Surgical Research. 130: 167. DOI: 10.1016/J.Jss.2005.11.019 |
0.447 |
|
| 2005 |
Detwiller KY, Fernando NT, Segal NH, Ryeom SW, D'Amore PA, Yoon SS. Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A. Cancer Research. 65: 5881-9. PMID 15994966 DOI: 10.1158/0008-5472.Can-04-4078 |
0.434 |
|
| 2003 |
Ryeom S, Greenwald RJ, Sharpe AH, McKeon F. The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin. Nature Immunology. 4: 874-81. PMID 12925851 DOI: 10.1038/Ni966 |
0.319 |
|
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