Kent E. Vrana - Publications

Pharmacology Pennsylvania State University, State College, PA, United States 
biogenic amines, stem cells, dopamine, drug abuse, alcoholism, tyrosine hydroxylase, tryptophan hydroxylase, parthenogenesis,

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Imperio CG, McFalls AJ, Hadad N, Blanco-Berdugo L, Masser DR, Colechio EM, Coffey AA, Bixler GV, Stanford DR, Vrana KE, Grigson PS, Freeman WM. Exposure to environmental enrichment attenuates addiction-like behavior and alters molecular effects of heroin self-administration in rats. Neuropharmacology. PMID 29964093 DOI: 10.1016/J.Neuropharm.2018.06.037  0.371
2015 Imperio CG, McFalls AJ, Colechio EM, Masser DR, Vrana KE, Grigson PS, Freeman WM. Assessment of individual differences in the rat nucleus accumbens transcriptome following taste-heroin extended access. Brain Research Bulletin. PMID 26733446 DOI: 10.1016/J.Brainresbull.2015.12.005  0.376
2015 McFalls AJ, Imperio CG, Bixler G, Freeman WM, Grigson PS, Vrana KE. Reward devaluation and heroin escalation is associated with differential expression of CRF signaling genes. Brain Research Bulletin. PMID 26655889 DOI: 10.1016/J.Brainresbull.2015.11.009  0.406
2014 Carkaci-Salli N, Salli U, Tekin I, Hengst JA, Zhao MK, Gilman TL, Andrews AM, Vrana KE. Functional characterization of the S41Y (C2755A) polymorphism of tryptophan hydroxylase 2. Journal of Neurochemistry. 130: 748-58. PMID 24899127 DOI: 10.1111/Jnc.12779  0.703
2012 Huber-Keener KJ, Liu X, Wang Z, Wang Y, Freeman W, Wu S, Planas-Silva MD, Ren X, Cheng Y, Zhang Y, Vrana K, Liu CG, Yang JM, Wu R. Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data. Plos One. 7: e41333. PMID 22844461 DOI: 10.1371/Journal.Pone.0041333  0.301
2012 Helms CM, Messaoudi I, Jeng S, Freeman WM, Vrana KE, Grant KA. A longitudinal analysis of circulating stress-related proteins and chronic ethanol self-administration in cynomolgus macaques. Alcoholism, Clinical and Experimental Research. 36: 995-1003. PMID 22141444 DOI: 10.1111/J.1530-0277.2011.01685.X  0.311
2011 Freeman WM, Vanguilder HD, Guidone E, Krystal JH, Grant KA, Vrana KE. Plasma proteomic alterations in non-human primates and humans after chronic alcohol self-administration. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 899-911. PMID 21303580 DOI: 10.1017/S1461145711000046  0.321
2011 Carkaci-Salli N, Salli U, Kuntz-Melcavage KL, Pennock MM, Ozgen H, Tekin I, Freeman WM, Vrana KE. TPH2 in the ventral tegmental area of the male rat brain. Brain Research Bulletin. 84: 376-80. PMID 21272616 DOI: 10.1016/J.Brainresbull.2011.01.006  0.756
2010 Mathew R, Jia W, Sharma A, Zhao Y, Clarke LE, Cheng X, Wang H, Salli U, Vrana KE, Robertson GP, Zhu J, Wang S. Robust activation of the human but not mouse telomerase gene during the induction of pluripotency. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2702-15. PMID 20354136 DOI: 10.1096/Fj.09-148973  0.332
2010 Umstead TM, Lu CJ, Freeman WM, Myers JL, Clark JB, Thomas NJ, Chinchilli VM, Vrana KE, Undar A, Phelps DS. Dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Pediatric Research. 67: 641-9. PMID 20308938 DOI: 10.1203/Pdr.0B013E3181Dceef5  0.328
2010 Freeman WM, Lull ME, Patel KM, Brucklacher RM, Morgan D, Roberts DC, Vrana KE. Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration. Bmc Neuroscience. 11: 29. PMID 20187946 DOI: 10.1186/1471-2202-11-29  0.758
2010 Lull ME, Freeman WM, VanGuilder HD, Vrana KE. The use of neuroproteomics in drug abuse research. Drug and Alcohol Dependence. 107: 11-22. PMID 19926406 DOI: 10.1016/J.Drugalcdep.2009.10.001  0.742
2009 Barthéléry M, Jaishankar A, Salli U, Freeman WM, Vrana KE. 2-D DIGE identification of differentially expressed heterogeneous nuclear ribonucleoproteins and transcription factors during neural differentiation of human embryonic stem cells. Proteomics. Clinical Applications. 3: 505-14. PMID 21136975 DOI: 10.1002/Prca.200800109  0.758
2009 Lull ME, Erwin MS, Morgan D, Roberts DC, Vrana KE, Freeman WM. Persistent proteomic alterations in the medial prefrontal cortex with abstinence from cocaine self-administration. Proteomics. Clinical Applications. 3: 462-472. PMID 20161123 DOI: 10.1002/Prca.200800055  0.76
2009 Kuntz-Melcavage KL, Brucklacher RM, Grigson PS, Freeman WM, Vrana KE. Gene expression changes following extinction testing in a heroin behavioral incubation model. Bmc Neuroscience. 10: 95. PMID 19664213 DOI: 10.1186/1471-2202-10-95  0.768
2009 Jaishankar A, Vrana KE. Emerging molecular approaches in stem cell biology Biotechniques. 46: 367-371. PMID 19480634 DOI: 10.2144/000113144  0.729
2009 Barthéléry M, Jaishankar A, Salli U, Vrana KE. Reptin52 expression during in vitro neural differentiation of human embryonic stem cells. Neuroscience Letters. 452: 47-51. PMID 19444951 DOI: 10.1016/J.Neulet.2009.01.023  0.749
2009 Jaishankar A, Barthelery M, Freeman WM, Salli U, Ritty TM, Vrana KE. Human embryonic and mesenchymal stem cells express different nuclear proteomes. Stem Cells and Development. 18: 793-802. PMID 18821827 DOI: 10.1089/Scd.2008.0156  0.75
2009 Salli U, Fox TE, Carkaci-Salli N, Sharma A, Robertson GP, Kester M, Vrana KE. Propagation of undifferentiated human embryonic stem cells with nano-liposomal ceramide. Stem Cells and Development. 18: 55-65. PMID 18393629 DOI: 10.1089/Scd.2007.0271  0.331
2008 Kuntz-Melcavage KL, Freeman WM, Vrana KE. CNS genes implicated in relapse. Substance Abuse : Research and Treatment. 2: 1-12. PMID 25922574 DOI: 10.4137/Sart.S1042  0.759
2008 Lull ME, Freeman WM, Vrana KE, Mash DC. Correlating human and animal studies of cocaine abuse and gene expression. Annals of the New York Academy of Sciences. 1141: 58-75. PMID 18991951 DOI: 10.1196/Annals.1441.013  0.758
2008 VanGuilder HD, Vrana KE, Freeman WM. Twenty-five years of quantitative PCR for gene expression analysis. Biotechniques. 44: 619-26. PMID 18474036 DOI: 10.2144/000112776  0.321
2008 Kuntz KL, Twining RC, Baldwin AE, Vrana KE, Grigson PS. Heroin self-administration: I. Incubation of goal-directed behavior in rats. Pharmacology, Biochemistry, and Behavior. 90: 344-8. PMID 18471868 DOI: 10.1016/J.Pbb.2008.03.018  0.308
2008 Kuntz KL, Patel KM, Grigson PS, Freeman WM, Vrana KE. Heroin self-administration: II. CNS gene expression following withdrawal and cue-induced drug-seeking behavior. Pharmacology, Biochemistry, and Behavior. 90: 349-56. PMID 18466961 DOI: 10.1016/J.Pbb.2008.03.019  0.393
2008 Lull ME, Carkaci-Salli N, Freeman WM, Myers JL, Midgley FM, Thomas NJ, Kimatian SJ, Vrana KE, Undar A. Plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Pediatric Research. 63: 638-44. PMID 18317239 DOI: 10.1203/Pdr.0B013E31816E391F  0.732
2008 Freeman WM, Patel KM, Brucklacher RM, Lull ME, Erwin M, Morgan D, Roberts DC, Vrana KE. Persistent alterations in mesolimbic gene expression with abstinence from cocaine self-administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1807-17. PMID 17851536 DOI: 10.1038/Sj.Npp.1301577  0.756
2007 Barthelery M, Salli U, Vrana KE. Nuclear proteomics and directed differentiation of embryonic stem cells. Stem Cells and Development. 16: 905-19. PMID 17999636 DOI: 10.1089/Scd.2007.0071  0.372
2007 Ward GR, Franklin SO, Gerald TM, Dempsey KT, Clodfelter DE, Krissinger DJ, Patel KM, Vrana KE, Howlett AC. Glucocorticoids plus opioids up-regulate genes that influence neuronal function. Cellular and Molecular Neurobiology. 27: 651-60. PMID 17554624 DOI: 10.1007/S10571-007-9151-3  0.319
2007 Bowyer JF, Pogge AR, Delongchamp RR, O'Callaghan JP, Patel KM, Vrana KE, Freeman WM. A threshold neurotoxic amphetamine exposure inhibits parietal cortex expression of synaptic plasticity-related genes. Neuroscience. 144: 66-76. PMID 17049170 DOI: 10.1016/J.Neuroscience.2006.08.076  0.343
2006 Cibelli JB, Cunniff K, Vrana KE. Embryonic stem cells from parthenotes. Methods in Enzymology. 418: 117-35. PMID 17141033 DOI: 10.1016/S0076-6879(06)18008-8  0.303
2006 Lull ME, Freeman WM, Myers JL, Midgley F, Kimatian SJ, Undar A, Vrana KE. Plasma proteomics: a noninvasive window on pathology and pediatric cardiac surgery. Asaio Journal (American Society For Artificial Internal Organs : 1992). 52: 562-6. PMID 16966860 DOI: 10.1097/01.Mat.0000237694.53808.78  0.726
2006 Freeman WM, Lull ME, Guilford MT, Vrana KE. Depletion of abundant proteins from non-human primate serum for biomarker studies. Proteomics. 6: 3109-13. PMID 16619306 DOI: 10.1002/Pmic.200500717  0.731
2006 Freeman WM, Gooch RS, Lull ME, Worst TJ, Walker SJ, Xu AS, Green H, Pierre PJ, Grant KA, Vrana KE. Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration. Alcohol and Alcoholism (Oxford, Oxfordshire). 41: 300-5. PMID 16581821 DOI: 10.1093/Alcalc/Agl021  0.73
2006 Hipp JD, Mychaleckyj JC, Cibelli JB, Wininger JD, Grant KA, Vrana KE. Parthenogenetic Stem Cells Reviews in Cell Biology and Molecular Medicine. 635-637. DOI: 10.1002/3527600906.Mcb.200400066  0.311
2005 McCracken CB, Hamby SM, Patel KM, Morgan D, Vrana KE, Roberts DC. Extended cocaine self-administration and deprivation produces region-specific and time-dependent changes in connexin36 expression in rat brain. Synapse (New York, N.Y.). 58: 141-50. PMID 16138316 DOI: 10.1002/Syn.20194  0.394
2005 Worst TJ, Tan JC, Robertson DJ, Freeman WM, Hyytia P, Kiianmaa K, Vrana KE. Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. Journal of Neuroscience Research. 80: 529-38. PMID 15846778 DOI: 10.1002/Jnr.20496  0.32
2005 McCracken CB, Patel KM, Vrana KE, Paul DL, Roberts DC. Amphetamine withdrawal produces region-specific and time-dependent changes in connexin36 expression in rat brain. Synapse (New York, N.Y.). 56: 39-44. PMID 15700285 DOI: 10.1002/Syn.20127  0.364
2003 Vrana KE, Hipp JD, Goss AM, McCool BA, Riddle DR, Walker SJ, Wettstein PJ, Studer LP, Tabar V, Cunniff K, Chapman K, Vilner L, West MD, Grant KA, Cibelli JB. Nonhuman primate parthenogenetic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 11911-6. PMID 14504386 DOI: 10.1073/Pnas.2034195100  0.317
2003 Vrana KE, Freeman WM, Aschner M. Use of microarray technologies in toxicology research. Neurotoxicology. 24: 321-32. PMID 12782098 DOI: 10.1016/S0161-813X(02)00193-6  0.327
2002 Freeman WM, Dougherty KE, Vacca SE, Vrana KE. An interactive database of cocaine-responsive gene expression. Thescientificworldjournal. 2: 701-6. PMID 12805995 DOI: 10.1100/Tsw.2002.145  0.397
2002 Stokes AH, Freeman WM, Mitchell SG, Burnette TA, Hellmann GM, Vrana KE. Induction of GADD45 and GADD153 in neuroblastoma cells by dopamine-induced toxicity. Neurotoxicology. 23: 675-84. PMID 12520757 DOI: 10.1016/S0161-813X(02)00093-1  0.345
2002 Freeman WM, Brebner K, Patel KM, Lynch WJ, Roberts DC, Vrana KE. Repeated cocaine self-administration causes multiple changes in rat frontal cortex gene expression. Neurochemical Research. 27: 1181-92. PMID 12462416 DOI: 10.1023/A:1020929526688  0.404
2002 Freeman WM, Brebner K, Lynch WJ, Patel KM, Robertson DJ, Roberts DC, Vrana KE. Changes in rat frontal cortex gene expression following chronic cocaine. Brain Research. Molecular Brain Research. 104: 11-20. PMID 12117546 DOI: 10.1016/S0169-328X(02)00197-3  0.415
2001 Freeman WM, Brebner K, Lynch WJ, Robertson DJ, Roberts DC, Vrana KE. Cocaine-responsive gene expression changes in rat hippocampus. Neuroscience. 108: 371-80. PMID 11738252 DOI: 10.1016/S0306-4522(01)00432-8  0.404
2001 Freeman WM, Nader MA, Nader SH, Robertson DJ, Gioia L, Mitchell SM, Daunais JB, Porrino LJ, Friedman DP, Vrana KE. Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression. Journal of Neurochemistry. 77: 542-9. PMID 11299316 DOI: 10.1046/J.1471-4159.2001.00252.X  0.404
2001 Freeman WM, Nader MA, Nader SH, Robertson DJ, Gioia L, Mitchell SM, Daunais JB, Porrino LJ, Friedman DP, Vrana KE. Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression: Correction Journal of Neurochemistry. 77: 1423-1423. DOI: 10.1046/J.1471-4159.2001.00382.X  0.372
2000 Freeman WM, Robertson DJ, Vrana KE. Fundamentals of DNA hybridization arrays for gene expression analysis. Biotechniques. 29: 1042-6, 1048-55. PMID 11084867 DOI: 10.2144/00295Rv01  0.305
2000 Freeman WM, Yohrling GJ, Daunais JB, Gioia L, Hart SL, Porrino LJ, Davies HM, Vrana KE. A cocaine analog, 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT), reduces tyrosine hydroxylase in the mesolimbic dopamine pathway. Drug and Alcohol Dependence. 61: 15-21. PMID 11064180 DOI: 10.1016/S0376-8716(00)00119-8  0.369
1997 Xu Y, Stokes AH, Freeman WM, Kumer SC, Vogt BA, Vrana KE. Tyrosinase mRNA is expressed in human substantia nigra. Brain Research. Molecular Brain Research. 45: 159-62. PMID 9105685 DOI: 10.1016/S0169-328X(96)00308-7  0.355
1993 Vrana SL, Vrana KE, Koves TR, Smith JE, Dworkin SI. Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity levels. Journal of Neurochemistry. 61: 2262-8. PMID 7902421 DOI: 10.1111/J.1471-4159.1993.Tb07468.X  0.359
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