Ghazaleh Sadri-Vakili - Publications

Massachusetts General Hospital, Boston, MA 
Huntington's disease, Addiction

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Mueller KA, Glajch KE, Huizenga MN, Wilson RA, Granucci EJ, Dios AM, Tousley AR, Iuliano M, Weisman E, LaQuaglia MJ, DiFiglia M, Kegel-Gleason K, Vakili K, Sadri-Vakili G. Hippo Signaling Pathway Dysregulation in Human Huntington's Disease Brain and Neuronal Stem Cells. Scientific Reports. 8: 11355. PMID 30054496 DOI: 10.1038/s41598-018-29319-4  0.48
2017 McCarthy DM, Mueller KA, Cannon EN, Huizenga MN, Darnell SB, Bhide PG, Sadri-Vakili G. Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain. Developmental Neuroscience. PMID 28132054 DOI: 10.1159/000453609  0.48
2016 McCarthy DM, Bell GA, Cannon EN, Mueller KA, Huizenga MN, Sadri-Vakili G, Fadool DA, Bhide PG. Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model. Developmental Neuroscience. PMID 27951531 DOI: 10.1159/000452739  0.48
2016 Batalha VL, Ferreira DG, Coelho JE, Valadas JS, Gomes R, Temido-Ferreira M, Shmidt T, Baqi Y, Buée L, Müller CE, Hamdane M, Outeiro TF, Bader M, Meijsing SH, Sadri-Vakili G, et al. The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. Scientific Reports. 6: 31493. PMID 27510168 DOI: 10.1038/srep31493  0.92
2015 Vodicka P, Mo S, Tousley A, Green KM, Sapp E, Iuliano M, Sadri-Vakili G, Shaffer SA, Aronin N, DiFiglia M, Kegel-Gleason KB. Mass Spectrometry Analysis of Wild-Type and Knock-in Q140/Q140 Huntington's Disease Mouse Brains Reveals Changes in Glycerophospholipids Including Alterations in Phosphatidic Acid and Lyso-Phosphatidic Acid. Journal of Huntington's Disease. 4: 187-201. PMID 26397899 DOI: 10.3233/JHD-150149  0.92
2015 Glajch KE, Sadri-Vakili G. Epigenetic Mechanisms Involved in Huntington's Disease Pathogenesis. Journal of Huntington's Disease. 4: 1-15. PMID 25813218 DOI: 10.3233/JHD-159001  0.92
2014 Satterlee JS, Basanta-Sanchez M, Blanco S, Li JB, Meyer K, Pollock J, Sadri-Vakili G, Rybak-Wolf A. Novel RNA modifications in the nervous system: form and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15170-7. PMID 25392485 DOI: 10.1523/JNEUROSCI.3236-14.2014  0.92
2014 Schmidt HD, McFarland KN, Darnell SB, Huizenga MN, Sangrey GR, Cha JH, Pierce RC, Sadri-Vakili G. ADAR2-dependent GluA2 editing regulates cocaine seeking. Molecular Psychiatry. PMID 25349168 DOI: 10.1038/mp.2014.134  0.92
2014 Sadri-Vakili G. Cocaine triggers epigenetic alterations in the corticostriatal circuit. Brain Research. PMID 25301690 DOI: 10.1016/j.brainres.2014.09.069  0.92
2014 Rasakham K, Schmidt HD, Kay K, Huizenga MN, Calcagno N, Pierce RC, Spires-Jones TL, Sadri-Vakili G. Synapse density and dendritic complexity are reduced in the prefrontal cortex following seven days of forced abstinence from cocaine self-administration. Plos One. 9: e102524. PMID 25072653 DOI: 10.1371/journal.pone.0102524  0.92
2014 Grijalva JL, Huizenga M, Mueller K, Rodriguez S, Brazzo J, Camargo F, Sadri-Vakili G, Vakili K. Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G196-204. PMID 24875096 DOI: 10.1152/ajpgi.00077.2014  0.92
2014 McFarland KN, Huizenga MN, Darnell SB, Sangrey GR, Berezovska O, Cha JH, Outeiro TF, Sadri-Vakili G. MeCP2: a novel Huntingtin interactor. Human Molecular Genetics. 23: 1036-44. PMID 24105466 DOI: 10.1093/hmg/ddt499  0.92
2014 Vassoler FM, Sadri-Vakili G. Mechanisms of transgenerational inheritance of addictive-like behaviors. Neuroscience. 264: 198-206. PMID 23920159 DOI: 10.1016/j.neuroscience.2013.07.064  0.92
2013 McFarland KN, Das S, Sun TT, Leyfer D, Kim MO, Xia E, Sangrey GR, Kuhn A, Luthi-Carter R, Clark TW, Sadri-Vakili G, Cha JH. Genome-wide increase in histone H2A ubiquitylation in a mouse model of Huntington's disease. Journal of Huntington's Disease. 2: 263-77. PMID 25062675 DOI: 10.3233/JHD-130066  0.92
2013 Licata SC, Shinday NM, Huizenga MN, Darnell SB, Sangrey GR, Rudolph U, Rowlett JK, Sadri-Vakili G. Alterations in brain-derived neurotrophic factor in the mouse hippocampus following acute but not repeated benzodiazepine treatment. Plos One. 8: e84806. PMID 24367698 DOI: 10.1371/journal.pone.0084806  0.92
2013 Vashishtha M, Ng CW, Yildirim F, Gipson TA, Kratter IH, Bodai L, Song W, Lau A, Labadorf A, Vogel-Ciernia A, Troncosco J, Ross CA, Bates GP, Krainc D, Sadri-Vakili G, et al. Targeting H3K4 trimethylation in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E3027-36. PMID 23872847 DOI: 10.1073/pnas.1311323110  0.92
2013 Schmidt HD, McGinty JF, West AE, Sadri-Vakili G. Epigenetics and psychostimulant addiction. Cold Spring Harbor Perspectives in Medicine. 3: a012047. PMID 23359110 DOI: 10.1101/cshperspect.a012047  0.92
2013 Vassoler FM, White SL, Schmidt HD, Sadri-Vakili G, Pierce RC. Epigenetic inheritance of a cocaine-resistance phenotype. Nature Neuroscience. 16: 42-7. PMID 23242310 DOI: 10.1038/nn.3280  0.92
2012 McFarland KN, Das S, Sun TT, Leyfer D, Xia E, Sangrey GR, Kuhn A, Luthi-Carter R, Clark TW, Sadri-Vakili G, Cha JH. Genome-wide histone acetylation is altered in a transgenic mouse model of Huntington's disease. Plos One. 7: e41423. PMID 22848491 DOI: 10.1371/journal.pone.0041423  0.92
2012 Jia H, Pallos J, Jacques V, Lau A, Tang B, Cooper A, Syed A, Purcell J, Chen Y, Sharma S, Sangrey GR, Darnell SB, Plasterer H, Sadri-Vakili G, Gottesfeld JM, et al. Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease. Neurobiology of Disease. 46: 351-61. PMID 22590724 DOI: 10.1016/j.nbd.2012.01.016  0.92
2012 Ritch JJ, Valencia A, Alexander J, Sapp E, Gatune L, Sangrey GR, Sinha S, Scherber CM, Zeitlin S, Sadri-Vakili G, Irimia D, Difiglia M, Kegel KB. Multiple phenotypes in Huntington disease mouse neural stem cells. Molecular and Cellular Neurosciences. 50: 70-81. PMID 22508027 DOI: 10.1016/j.mcn.2012.03.011  0.92
2012 Schmidt HD, Sangrey GR, Darnell SB, Schassburger RL, Cha JH, Pierce RC, Sadri-Vakili G. Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation at BDNF exon I-containing promoters. Journal of Neurochemistry. 120: 202-9. PMID 22043863 DOI: 10.1111/j.1471-4159.2011.07571.x  0.92
2011 McCarthy DM, Zhang X, Darnell SB, Sangrey GR, Yanagawa Y, Sadri-Vakili G, Bhide PG. Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13400-11. PMID 21940433 DOI: 10.1523/JNEUROSCI.2944-11.2011  0.92
2010 Sadri-Vakili G, Kumaresan V, Schmidt HD, Famous KR, Chawla P, Vassoler FM, Overland RP, Xia E, Bass CE, Terwilliger EF, Pierce RC, Cha JH. Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11735-44. PMID 20810894 DOI: 10.1523/JNEUROSCI.2328-10.2010  0.92
2010 Benn CL, Luthi-Carter R, Kuhn A, Sadri-Vakili G, Blankson KL, Dalai SC, Goldstein DR, Spires TL, Pritchard J, Olson JM, van Dellen A, Hannan AJ, Cha JH. Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease. Journal of Neuropathology and Experimental Neurology. 69: 817-27. PMID 20613636 DOI: 10.1097/NEN.0b013e3181ea167f  0.92
2008 Famous KR, Kumaresan V, Sadri-Vakili G, Schmidt HD, Mierke DF, Cha JH, Pierce RC. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11061-70. PMID 18945913 DOI: 10.1523/JNEUROSCI.1221-08.2008  0.92
2008 Benn CL, Sun T, Sadri-Vakili G, McFarland KN, DiRocco DP, Yohrling GJ, Clark TW, Bouzou B, Cha JH. Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10720-33. PMID 18923047 DOI: 10.1523/JNEUROSCI.2126-08.2008  0.92
2008 Sadri-Vakili G, Janis GC, Pierce RC, Gibbs TT, Farb DH. Nanomolar concentrations of pregnenolone sulfate enhance striatal dopamine overflow in vivo. The Journal of Pharmacology and Experimental Therapeutics. 327: 840-5. PMID 18772319 DOI: 10.1124/jpet.108.143958  0.92
2008 Broom WJ, Greenway M, Sadri-Vakili G, Russ C, Auwarter KE, Glajch KE, Dupre N, Swingler RJ, Purcell S, Hayward C, Sapp PC, McKenna-Yasek D, Valdmanis PN, Bouchard JP, Meininger V, et al. 50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 9: 229-37. PMID 18608091 DOI: 10.1080/17482960802103107  0.92
2008 Kim MO, Chawla P, Overland RP, Xia E, Sadri-Vakili G, Cha JH. Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3947-57. PMID 18400894 DOI: 10.1523/JNEUROSCI.5667-07.2008  0.92
2008 Anderson SM, Famous KR, Sadri-Vakili G, Kumaresan V, Schmidt HD, Bass CE, Terwilliger EF, Cha JH, Pierce RC. CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking. Nature Neuroscience. 11: 344-53. PMID 18278040 DOI: 10.1038/nn2054  0.92
2008 Anderson SM, Famous KR, Sadri-Vakili G, Kumaresan V, Schmidt HD, Bass CE, Terwilliger EF, Cha JHJ, Pierce RC. CaMKII: A biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking (Nature Neuroscience (2008) 11, 344-353) Nature Neuroscience. 11: 617. DOI: 10.1038/nn0508-617  0.92
2007 Sadri-Vakili G, Bouzou B, Benn CL, Kim MO, Chawla P, Overland RP, Glajch KE, Xia E, Qiu Z, Hersch SM, Clark TW, Yohrling GJ, Cha JH. Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models. Human Molecular Genetics. 16: 1293-306. PMID 17409194 DOI: 10.1093/hmg/ddm078  0.92
2006 Sadri-Vakili G, Cha JH. Histone deacetylase inhibitors: a novel therapeutic approach to Huntington's disease (complex mechanism of neuronal death). Current Alzheimer Research. 3: 403-8. PMID 17017871 DOI: 10.2174/156720506778249407  0.92
2006 Sadri-Vakili G, Cha JH. Mechanisms of disease: Histone modifications in Huntington's disease. Nature Clinical Practice. Neurology. 2: 330-8. PMID 16932577 DOI: 10.1038/ncpneuro0199  0.92
2006 Sadri-Vakili G, Menon AS, Farrell LA, Keller-McGandy CE, Cantuti-Castelvetri I, Standaert DG, Augood SJ, Yohrling GJ, Cha JH. Huntingtin inclusions do not down-regulate specific genes in the R6/2 Huntington's disease mouse. The European Journal of Neuroscience. 23: 3171-5. PMID 16820007 DOI: 10.1111/j.1460-9568.2006.04871.x  0.92
2006 Chen-Plotkin AS, Sadri-Vakili G, Yohrling GJ, Braveman MW, Benn CL, Glajch KE, DiRocco DP, Farrell LA, Krainc D, Gines S, MacDonald ME, Cha JH. Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease. Neurobiology of Disease. 22: 233-41. PMID 16442295 DOI: 10.1016/j.nbd.2005.11.001  0.92
2003 Sadri-Vakili G, Johnson DW, Janis GC, Gibbs TT, Pierce RC, Farb DH. Inhibition of NMDA-induced striatal dopamine release and behavioral activation by the neuroactive steroid 3alpha-hydroxy-5beta-pregnan-20-one hemisuccinate. Journal of Neurochemistry. 86: 92-101. PMID 12807429 DOI: 10.1046/j.1471-4159.2003.01814.x  0.92
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