Alice Chen-Plotkin - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neurodegeneration

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Reus LM, Jansen IE, Tijms BM, Visser PJ, Tesi N, van der Lee SJ, Vermunt L, Peeters CFW, De Groot LA, Hok-A-Hin YS, Chen-Plotkin A, Irwin DJ, Hu WT, Meeter LH, van Swieten JC, et al. Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia. Brain : a Journal of Neurology. PMID 38527854 DOI: 10.1093/brain/awae090  0.304
2024 Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L. Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38328211 DOI: 10.1101/2024.01.23.576728  0.598
2024 Cousins KAQ, Irwin DJ, Tropea TF, Rhodes E, Phillips J, Chen-Plotkin AS, Brumm MC, Coffey CS, Kang JH, Simuni T, Foroud TM, Toga AW, Tanner CM, Kieburtz KD, Mollenhauer B, et al. Evaluation of ATN Framework and Biofluid Markers to Predict Cognitive Decline in Early Parkinson Disease. Neurology. 102: e208033. PMID 38306599 DOI: 10.1212/WNL.0000000000208033  0.369
2024 Arezoumandan S, Cousins KAQ, Ohm DT, Lowe M, Chen M, Gee J, Phillips JS, McMillan CT, Luk KC, Deik A, Spindler MA, Tropea TF, Weintraub D, Wolk DA, Grossman M, ... ... Chen-Plotkin AS, et al. Tau maturation in the clinicopathological spectrum of Lewy body and Alzheimer's disease. Annals of Clinical and Translational Neurology. PMID 38263854 DOI: 10.1002/acn3.51988  0.798
2023 Diaz-Ortiz ME, Jain N, Gallagher MD, Posavi M, Unger TL, Chen-Plotkin AS. Testing for Allele-specific Expression from Human Brain Samples. Bio-Protocol. 13: e4832. PMID 37817908 DOI: 10.21769/BioProtoc.4832  0.808
2023 Kang JH, Korecka M, Lee EB, Cousins KAQ, Tropea TF, Chen-Plotkin AA, Irwin DJ, Wolk D, Brylska M, Wan Y, Shaw LM. Alzheimer Disease Biomarkers: Moving from CSF to Plasma for Reliable Detection of Amyloid and tau Pathology. Clinical Chemistry. PMID 37725909 DOI: 10.1093/clinchem/hvad139  0.465
2023 van der Ende EL, In 't Veld SGJG, Hanskamp I, van der Lee S, Dijkstra JIR, Hok-A-Hin YS, Blujdea ER, van Swieten JC, Irwin DJ, Chen-Plotkin A, Hu WT, Lemstra AW, Pijnenburg YAL, van der Flier WM, Del Campo M, et al. CSF proteomics in autosomal dominant Alzheimer's disease highlights parallels with sporadic disease. Brain : a Journal of Neurology. PMID 37348871 DOI: 10.1093/brain/awad213  0.548
2023 Carceles-Cordon M, Weintraub D, Chen-Plotkin AS. Cognitive heterogeneity in Parkinson's disease: A mechanistic view. Neuron. 111: 1531-1546. PMID 37028431 DOI: 10.1016/j.neuron.2023.03.021  0.325
2023 Cousins KAQ, Irwin DJ, Chen-Plotkin A, Shaw LM, Arezoumandan S, Lee EB, Wolk DA, Weintraub D, Spindler M, Deik A, Grossman M, Tropea TF. Plasma GFAP associates with secondary Alzheimer's pathology in Lewy body disease. Annals of Clinical and Translational Neurology. PMID 37000892 DOI: 10.1002/acn3.51768  0.492
2023 Neel DV, Basu H, Gunner G, Bergstresser MD, Giadone RM, Chung H, Miao R, Chou V, Brody E, Jiang X, Lee E, Watts ME, Marques C, Held A, Wainger B, ... ... Chen-Plotkin AS, et al. Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration. Neuron. PMID 36917977 DOI: 10.1016/j.neuron.2023.02.019  0.377
2023 Tropea TF, Albuja I, Cousins KAQ, Irwin DJ, Lee EB, Chen-Plotkin AS. Concomitant Alzheimer's Disease Pathology in Parkinson's Disease Dementia. Annals of Neurology. PMID 36892304 DOI: 10.1002/ana.26635  0.533
2023 Robinson JL, Xie SX, Baer DR, Suh E, Van Deerlin VM, Loh NJ, Irwin D, McMillan CT, Wolk D, Chen-Plotkin A, Weintraub D, Schuck T, Lee VM, Trojanowski JQ, Lee EB. Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated. Brain : a Journal of Neurology. PMID 36864661 DOI: 10.1093/brain/awad059  0.642
2022 Del Campo M, Peeters CFW, Johnson ECB, Vermunt L, Hok-A-Hin YS, van Nee M, Chen-Plotkin A, Irwin DJ, Hu WT, Lah JJ, Seyfried NT, Dammer EB, Herradon G, Meeter LH, van Swieten J, et al. CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature Aging. 2: 1040-1053. PMID 37118088 DOI: 10.1038/s43587-022-00300-1  0.555
2022 Tropea TF, Waligorska T, Xie SX, Nasrallah IM, Cousins KAQ, Trojanowski JQ, Grossman M, Irwin DJ, Weintraub D, Lee EB, Wolk DA, Chen-Plotkin AS, Shaw LM. Plasma phosphorylated tau181 predicts cognitive and functional decline. Annals of Clinical and Translational Neurology. PMID 36518085 DOI: 10.1002/acn3.51695  0.532
2022 Nilsson J, Cousins KAQ, Gobom J, Portelius E, Chen-Plotkin A, Shaw LM, Grossman M, Irwin DJ, Trojanowski JQ, Zetterberg H, Blennow K, Brinkmalm A. Cerebrospinal fluid biomarker panel of synaptic dysfunction in Alzheimer's disease and other neurodegenerative disorders. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36239248 DOI: 10.1002/alz.12809  0.427
2022 Cousins KAQ, Shaw LM, Chen-Plotkin A, Wolk DA, Van Deerlin VM, Lee EB, McMillan CT, Grossman M, Irwin DJ. Distinguishing Frontotemporal Lobar Degeneration Tau From TDP-43 Using Plasma Biomarkers. Jama Neurology. PMID 36215050 DOI: 10.1001/jamaneurol.2022.3265  0.449
2022 Quilico Cousins KA, Arezoumandan S, Shellikeri S, Ohm D, Shaw LM, Grossman M, Wolk D, McMillan CT, Chen-Plotkin A, Lee E, Trojanowski JQ, Zetterberg H, Blennow K, Irwin DJ. CSF Biomarkers of Alzheimer Disease in Patients With Concomitant α-Synuclein Pathology. Neurology. PMID 36041863 DOI: 10.1212/WNL.0000000000201202  0.776
2022 Diaz-Ortiz ME, Seo Y, Posavi M, Carceles Cordon M, Clark E, Jain N, Charan R, Gallagher MD, Unger TL, Amari N, Skrinak RT, Davila-Rivera R, Brody EM, Han N, Zack R, ... ... Chen-Plotkin AS, et al. GPNMB confers risk for Parkinson's disease through interaction with α-synuclein. Science (New York, N.Y.). 377: eabk0637. PMID 35981040 DOI: 10.1126/science.abk0637  0.723
2022 Cousins KAQ, Shaw LM, Shellikeri S, Dratch L, Rosario L, Elman LB, Quinn C, Amado DA, Wolk DA, Tropea TF, Chen-Plotkin A, Irwin DJ, Grossman M, Lee EB, Trojanowski JQ, et al. Elevated plasma phosphorylated tau 181 in amyotrophic lateral sclerosis. Annals of Neurology. PMID 35877814 DOI: 10.1002/ana.26462  0.784
2022 Weintraub D, Posavi M, Fontanillas P, Tropea TF, Mamikonyan E, Suh E, Trojanowski JQ, Cannon P, Van Deerlin VM, Chen-Plotkin AS. Genetic prediction of impulse control disorders in Parkinson's disease. Annals of Clinical and Translational Neurology. PMID 35762106 DOI: 10.1002/acn3.51569  0.455
2022 Walker IM, Cousins KA, Siderowf A, Duda JE, Morley JF, Dahodwala N, Tropea T, Vaishnavi S, Wolk DA, Chen-Plotkin AS, Shaw LM, Lee EB, Trojanowski JQ, Grossman M, Weintraub D, et al. Non-tremor motor dysfunction in Lewy body dementias is associated with AD biomarkers. Parkinsonism & Related Disorders. 100: 33-36. PMID 35700626 DOI: 10.1016/j.parkreldis.2022.05.022  0.579
2022 Blömeke L, Pils M, Kraemer-Schulien V, Dybala A, Schaffrath A, Kulawik A, Rehn F, Cousin A, Nischwitz V, Willbold J, Zack R, Tropea TF, Bujnicki T, Tamgüney G, Weintraub D, ... ... Chen-Plotkin A, et al. Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting. Npj Parkinson's Disease. 8: 68. PMID 35655068 DOI: 10.1038/s41531-022-00330-x  0.474
2022 Shen J, Amari N, Zack R, Skrinak RT, Unger TL, Posavi M, Tropea TF, Xie SX, Van Deerlin VM, Dewey RB, Weintraub D, Trojanowski JQ, Chen-Plotkin AS. Plasma MIA, CRP, and albumin predict cognitive decline in Parkinson's Disease. Annals of Neurology. PMID 35593028 DOI: 10.1002/ana.26410  0.426
2022 Cervantes González A, Irwin DJ, Alcolea D, McMillan CT, Chen-Plotkin A, Wolk D, Sirisi S, Dols-Icardo O, Querol-Vilaseca M, Illán-Gala I, Santos-Santos MA, Fortea J, Lee EB, Trojanowski JQ, Grossman M, et al. Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration. Molecular Neurodegeneration. 17: 29. PMID 35395770 DOI: 10.1186/s13024-022-00534-y  0.507
2022 Aamodt WW, Chen-Plotkin AS. Reply to: "Age-Adjusted Serum Neurofilament Predicts Cognitive Decline in Parkinson's Disease (MARK-PD)". Movement Disorders : Official Journal of the Movement Disorder Society. 37: 436-437. PMID 35150470 DOI: 10.1002/mds.28920  0.327
2022 Li R, Tropea TF, Baratta LR, Zuroff L, Diaz-Ortiz ME, Zhang B, Shinoda K, Rezk A, Alcalay RN, Chen-Plotkin A, Bar-Or A. Abnormal B-Cell and Tfh-Cell Profiles in Patients With Parkinson Disease: A Cross-sectional Study. Neurology(R) Neuroimmunology & Neuroinflammation. 9. PMID 34955458 DOI: 10.1212/NXI.0000000000001125  0.801
2021 Campo MD, Pijnenburg YAL, Chen-Plotkin A, Irwin DJ, Grossman M, Twaalfhoven HAM, Hu WT, Meeter LH, van Swieten J, Vermunt L, Martens F, Heijboer AC, Teunissen CE. Sex Hormone-Binding Globulin (SHBG) in Cerebrospinal Fluid Does Not Discriminate between the Main FTLD Pathological Subtypes but Correlates with Cognitive Decline in FTLD Tauopathies. Biomolecules. 11. PMID 34680117 DOI: 10.3390/biom11101484  0.516
2021 Tropea TF, Chen-Plotkin A. Are Parkinson's Disease Patients the Ideal Preclinical Population for Alzheimer's Disease Therapeutics? Journal of Personalized Medicine. 11. PMID 34575610 DOI: 10.3390/jpm11090834  0.395
2021 Aamodt WW, Waligorska T, Shen J, Tropea TF, Siderowf A, Weintraub D, Grossman M, Irwin D, Wolk DA, Xie SX, Trojanowski JQ, Shaw LM, Chen-Plotkin AS. Neurofilament Light Chain as a Biomarker for Cognitive Decline in Parkinson Disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 34480363 DOI: 10.1002/mds.28779  0.366
2021 Mao F, Robinson JL, Unger T, Posavi M, Amado DA, Elman L, Grossman M, Wolk DA, Lee EB, Van Deerlin VM, Porta S, Lee VMY, Trojanowski JQ, Chen-Plotkin AS. TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy. Acta Neuropathologica. PMID 34152475 DOI: 10.1007/s00401-021-02330-2  0.793
2021 Zhang JV, Irwin DJ, Blennow K, Zetterberg H, Lee EB, Shaw LM, Rascovsky K, Massimo L, McMillan CT, Chen-Plotkin A, Elman L, Lee VM, McCluskey L, Toledo JB, Weintraub D, et al. Neurofilament Light Chain Related to Longitudinal Decline in Frontotemporal Lobar Degeneration. Neurology. Clinical Practice. 11: 105-116. PMID 33842063 DOI: 10.1212/CPJ.0000000000000959  0.608
2021 Howard E, Irwin DJ, Rascovsky K, Nevler N, Shellikeri S, Tropea TF, Spindler M, Deik A, Chen-Plotkin A, Siderowf A, Dahodwala N, Weintraub D, Shaw LM, Trojanowski JQ, Vaishnavi SN, et al. Cognitive Profile and Markers of AD-Type Pathology in Patients with Lewy Body Dementias. Neurology. PMID 33593865 DOI: 10.1212/WNL.0000000000011699  0.396
2021 Wie J, Liu Z, Song H, Tropea TF, Yang L, Wang H, Liang Y, Cang C, Aranda K, Lohmann J, Yang J, Lu B, Chen-Plotkin AS, Luk KC, Ren D. A growth-factor-activated lysosomal K channel regulates Parkinson's pathology. Nature. PMID 33505021 DOI: 10.1038/s41586-021-03185-z  0.322
2021 Tropea TF, Amari N, Han N, Rick J, Suh E, Akhtar RS, Dahodwala N, Deik A, Gonzalez-Alegre P, Hurtig H, Siderowf A, Spindler M, Stern M, Thenganatt MA, Weintraub D, ... ... Chen-Plotkin A, et al. Whole Clinic Research Enrollment in Parkinson's Disease: The Molecular Integration in Neurological Diagnosis (MIND) Study. Journal of Parkinson's Disease. PMID 33492247 DOI: 10.3233/JPD-202406  0.326
2020 Gallagher J, Rick J, Xie SX, Martinez-Martin P, Mamikonyan E, Chen-Plotkin A, Dahodwala N, Morley J, Duda JE, Trojanowski JQ, Siderowf A, Weintraub D. Psychometric Properties of the Clinical Dementia Rating Scale Sum of Boxes in Parkinson's Disease. Journal of Parkinson's Disease. PMID 33386814 DOI: 10.3233/JPD-202390  0.472
2020 Spotorno N, Coughlin DG, Olm CA, Wolk D, Vaishnavi SN, Shaw LM, Dahodwala N, Morley JF, Duda JE, Deik AF, Spindler MA, Chen-Plotkin A, Lee EB, Trojanowski JQ, McMillan CT, et al. Tau pathology associates with in vivo cortical thinning in Lewy body disorders. Annals of Clinical and Translational Neurology. PMID 33108692 DOI: 10.1002/acn3.51183  0.537
2020 Dai DL, Tropea TF, Robinson JL, Suh E, Hurtig H, Weintraub D, Van Deerlin V, Lee EB, Trojanowski JQ, Chen-Plotkin AS. ADNC-RS, a clinical-genetic risk score, predicts Alzheimer's pathology in autopsy-confirmed Parkinson's disease and Dementia with Lewy bodies. Acta Neuropathologica. PMID 32749525 DOI: 10.1007/S00401-020-02199-7  0.629
2020 Purri R, Brennan L, Rick J, Xie SX, Deck BL, Chahine LM, Dahodwala N, Chen-Plotkin A, Duda JE, Morley JF, Akhtar RS, Trojanowski JQ, Siderowf A, Weintraub D. Subjective Cognitive Complaint in Parkinson's Disease Patients with Normal Cognition: Canary in the Coal Mine? Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32520435 DOI: 10.1002/Mds.28115  0.407
2020 Diaz-Ortiz ME, Chen-Plotkin AS. Omics in Neurodegenerative Disease: Hope or Hype? Trends in Genetics : Tig. 36: 152-159. PMID 31932096 DOI: 10.1016/j.tig.2019.12.002  0.82
2019 Posavi M, Diaz-Ortiz M, Liu B, Swanson CR, Skrinak RT, Hernandez-Con P, Amado DA, Fullard M, Rick J, Siderowf A, Weintraub D, McCluskey L, Trojanowski JQ, Dewey RB, Huang X, ... Chen-Plotkin AS, et al. Characterization of Parkinson's disease using blood-based biomarkers: A multicohort proteomic analysis. Plos Medicine. 16: e1002931. PMID 31603904 DOI: 10.1371/Journal.Pmed.1002931  0.794
2019 Deck BL, Xie SX, Choi G, Rick J, Siderowf A, Rudovsky S, Chen-Plotkin A, Duda JE, Morley JF, Dahodwala N, Trojanowski JQ, Weintraub D. Cognitive Functional Abilities in Parkinson's Disease: Agreement Between Patients and Informants. Movement Disorders Clinical Practice. 6: 440-445. PMID 31392244 DOI: 10.1002/Mdc3.12781  0.457
2019 Tropea TF, Mak J, Guo MH, Xie SX, Suh E, Rick J, Siderowf A, Weintraub D, Grossman M, Irwin D, Wolk DA, Trojanowski JQ, Van Deerlin V, Chen-Plotkin AS. TMEM106B Effect on Cognition in Parkinson's Disease and Frontotemporal Dementia. Annals of Neurology. PMID 30973966 DOI: 10.1002/Ana.25486  0.455
2019 Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Author Correction: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 10: 555. PMID 30696825 DOI: 10.1038/S41467-019-08562-X  0.304
2019 Toledo JB, Kovacs G, Kvartsberg H, Portelius E, Chen-Plotkin A, Zetterberg H, Blennow K, Shaw LM, Trojanowski JQ. P1-245: CSF BIOMARKER CORRELATES OF ARTAG NEUROPATHOLOGY Alzheimer's & Dementia. 15: P332-P332. DOI: 10.1016/J.Jalz.2019.06.800  0.308
2019 Waligorska T, Figurski MJ, Jeromin A, Chen-Plotkin A, Trojanowski JQ, Shaw LM. P3-232: VALIDATION STUDIES OF NEUROFILAMENT LIGHT AND Aβ-40 AND Aβ-42 ASSAYS IN HUMAN PLASMA USING THE SIMOA PLATFORM Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3262  0.326
2018 Chen-Plotkin AS, Zetterberg H. Updating Our Definitions of Parkinson's Disease for a Molecular Age. Journal of Parkinson's Disease. 8: S53-S57. PMID 30584165 DOI: 10.3233/JPD-181487  0.365
2018 Amado DA, Rieders JM, Diatta F, Hernandez-Con P, Singer A, Mak JT, Zhang J, Lancaster E, Davidson BL, Chen-Plotkin AS. AAV-Mediated Progranulin Delivery to a Mouse Model of Progranulin Deficiency Causes T Cell-Mediated Toxicity. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30559071 DOI: 10.1016/J.Ymthe.2018.11.013  0.72
2018 Olsson B, Portelius E, Cullen NC, Sandelius Å, Zetterberg H, Andreasson U, Höglund K, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk D, McCluskey L, Elman L, Shaw LM, et al. Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders. Jama Neurology. PMID 30508027 DOI: 10.1001/Jamaneurol.2018.3746  0.549
2018 Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 9: 4406. PMID 30353006 DOI: 10.1038/S41467-018-06543-0  0.436
2018 Sandelius Å, Portelius E, Källén Å, Zetterberg H, Rot U, Olsson B, Toledo JB, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, et al. Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30321501 DOI: 10.1016/J.Jalz.2018.08.006  0.467
2018 Chen-Plotkin AS, Albin R, Alcalay R, Babcock D, Bajaj V, Bowman D, Buko A, Cedarbaum J, Chelsky D, Cookson MR, Dawson TM, Dewey R, Foroud T, Frasier M, German D, et al. Finding useful biomarkers for Parkinson's disease. Science Translational Medicine. 10. PMID 30111645 DOI: 10.1126/Scitranslmed.Aam6003  0.32
2018 Jain N, Chen-Plotkin AS. Genetic Modifiers in Neurodegeneration. Current Genetic Medicine Reports. 6: 11-19. PMID 29977663 DOI: 10.1007/s40142-018-0133-1  0.393
2018 Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Yousef A, Hurtig HI, Siderowf A, Grossman M, McMillan CT, Miller B, ... ... Chen-Plotkin A, et al. Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated. Brain : a Journal of Neurology. PMID 29878075 DOI: 10.1093/Brain/Awy146  0.673
2018 Gallagher MD, Chen-Plotkin AS. The Post-GWAS Era: From Association to Function. American Journal of Human Genetics. 102: 717-730. PMID 29727686 DOI: 10.1016/j.ajhg.2018.04.002  0.589
2018 Portelius E, Olsson B, Höglund K, Cullen NC, Kvartsberg H, Andreasson U, Zetterberg H, Sandelius Å, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, et al. Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology. Acta Neuropathologica. PMID 29700597 DOI: 10.1007/S00401-018-1851-X  0.457
2018 Shi M, Tang L, Toledo JB, Ginghina C, Wang H, Aro P, Jensen PH, Weintraub D, Chen-Plotkin AS, Irwin DJ, Grossman M, McCluskey L, Elman LB, Wolk DA, Lee EB, et al. Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29604263 DOI: 10.1016/J.Jalz.2018.02.015  0.554
2018 Irwin DJ, Xie SX, Coughlin D, Nevler N, Akhtar RS, McMillan CT, Lee EB, Wolk DA, Weintraub D, Chen-Plotkin A, Duda JE, Spindler M, Siderowf A, Hurtig HI, Shaw LM, et al. CSF tau and amyloid-beta predict cerebral synucleinopathy in autopsied Lewy body disorders. Neurology. PMID 29467305 DOI: 10.1212/Wnl.0000000000005166  0.487
2018 Chen-Plotkin AS. Parkinson disease: Blood transcriptomics for Parkinson disease? Nature Reviews. Neurology. 14: 5-6. PMID 29192261 DOI: 10.1038/nrneurol.2017.166  0.335
2018 Tropea TF, Chen-Plotkin AS. Unlocking the mystery of biomarkers: A brief introduction, challenges and opportunities in Parkinson Disease. Parkinsonism & Related Disorders. 46: S15-S18. PMID 28793971 DOI: 10.1016/j.parkreldis.2017.07.021  0.3
2017 Tropea TF, Xie SX, Rick J, Chahine LM, Dahodwala N, Doshi J, Davatzikos C, Shaw LM, Van Deerlin V, Trojanowski JQ, Weintraub D, Chen-Plotkin AS. APOE, thought disorder, and SPARE-AD predict cognitive decline in established Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29168904 DOI: 10.1002/Mds.27204  0.451
2017 Sheinerman KS, Toledo JB, Tsivinsky VG, Irwin D, Grossman M, Weintraub D, Hurtig HI, Chen-Plotkin A, Wolk DA, McCluskey LF, Elman LB, Trojanowski JQ, Umansky SR. Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases. Alzheimer's Research & Therapy. 9: 89. PMID 29121998 DOI: 10.1186/S13195-017-0316-0  0.539
2017 Gallagher MD, Posavi M, Huang P, Unger TL, Berlyand Y, Gruenewald AL, Chesi A, Manduchi E, Wells AD, Grant SFA, Blobel GA, Brown CD, Chen-Plotkin AS. A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression. American Journal of Human Genetics. PMID 29056226 DOI: 10.1016/J.Ajhg.2017.09.004  0.641
2017 Deck BL, Rick J, Xie SX, Chen-Plotkin A, Duda JE, Morley JF, Chahine LM, Dahodwala N, Trojanowski JQ, Weintraub D. Statins and Cognition in Parkinson's Disease. Journal of Parkinson's Disease. PMID 28922167 DOI: 10.3233/Jpd-171113  0.42
2017 Gwinn K, David KK, Swanson-Fischer C, Albin R, Hillaire-Clarke CS, Sieber BA, Lungu C, Bowman FD, Alcalay RN, Babcock D, Dawson TM, Dewey RB, Foroud T, German D, Huang X, ... ... Chen-Plotkin A, et al. Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program. Biomarkers in Medicine. PMID 28644039 DOI: 10.2217/Bmm-2016-0370  0.366
2017 McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, ... ... Chen-Plotkin A, et al. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology. PMID 28592453 DOI: 10.1212/Wnl.0000000000004058  0.397
2017 Akhtar RS, Xie SX, Chen YJ, Rick J, Gross RG, Nasrallah IM, Van Deerlin VM, Trojanowski JQ, Chen-Plotkin AS, Hurtig HI, Siderowf AD, Dubroff JG, Weintraub D. Regional brain amyloid-β accumulation associates with domain-specific cognitive performance in Parkinson disease without dementia. Plos One. 12: e0177924. PMID 28542444 DOI: 10.1371/Journal.Pone.0177924  0.385
2017 Brennan L, Devlin KM, Xie SX, Mechanic-Hamilton D, Tran B, Hurtig HH, Chen-Plotkin A, Chahine LM, Morley JF, Duda JE, Roalf DR, Dahodwala N, Rick J, Trojanowski JQ, Moberg PJ, et al. Neuropsychological Subgroups in Non-Demented Parkinson's Disease: A Latent Class Analysis. Journal of Parkinson's Disease. PMID 28387684 DOI: 10.3233/Jpd-171081  0.465
2017 Espay AJ, Schwarzschild MA, Tanner CM, Fernandez HH, Simon DK, Leverenz JB, Merola A, Chen-Plotkin A, Brundin P, Kauffman MA, Erro R, Kieburtz K, Woo D, Macklin EA, Standaert DG, et al. Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 28233927 DOI: 10.1002/Mds.26913  0.348
2017 Cooper CA, Jain N, Gallagher MD, Weintraub D, Xie SX, Berlyand Y, Espay AJ, Quinn J, Edwards KL, Montine T, Van Deerlin VM, Trojanowski J, Zabetian CP, Chen-Plotkin AS. Common variant rs356182 near SNCA defines a Parkinson's disease endophenotype. Annals of Clinical and Translational Neurology. 4: 15-25. PMID 28078311 DOI: 10.1002/Acn3.371  0.681
2016 Davis MY, Johnson CO, Leverenz JB, Weintraub D, Trojanowski JQ, Chen-Plotkin A, Van Deerlin VM, Quinn JF, Chung KA, Peterson-Hiller AL, Rosenthal LS, Dawson TM, Albert MS, Goldman JG, Stebbins GT, et al. Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease. Jama Neurology. PMID 27571329 DOI: 10.1001/Jamaneurol.2016.2245  0.511
2016 Lim NS, Swanson CR, Cherng HR, Unger TL, Xie SX, Weintraub D, Marek K, Stern MB, Siderowf A, Trojanowski JQ, Chen-Plotkin AS. Plasma EGF and cognitive decline in Parkinson's disease and Alzheimer's disease. Annals of Clinical and Translational Neurology. 3: 346-55. PMID 27231704 DOI: 10.1002/Acn3.299  0.762
2016 Busch JI, Unger TL, Jain N, Skrinak RT, Charan RA, Chen-Plotkin AS. Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes. Human Molecular Genetics. PMID 27126638 DOI: 10.1093/Hmg/Ddw127  0.767
2016 Kang JH, Mollenhauer B, Coffey CS, Toledo JB, Weintraub D, Galasko DR, Irwin DJ, Van Deerlin V, Chen-Plotkin AS, Caspell-Garcia C, Waligórska T, Taylor P, Shah N, Pan S, Zero P, et al. CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study. Acta Neuropathologica. PMID 27021906 DOI: 10.1007/S00401-016-1552-2  0.518
2016 Berlyand Y, Weintraub D, Xie SX, Mellis IA, Doshi J, Rick J, McBride J, Davatzikos C, Shaw LM, Hurtig H, Trojanowski JQ, Chen-Plotkin AS. An Alzheimer's Disease-Derived Biomarker Signature Identifies Parkinson's Disease Patients with Dementia. Plos One. 11: e0147319. PMID 26812251 DOI: 10.1371/Journal.Pone.0147319  0.497
2015 Swanson CR, Alcalay RN, Chen-Plotkin A. Reply to letter: Plasma fasting cholesterol profiles and age at onset in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 1975-6. PMID 26584479 DOI: 10.1002/mds.26447  0.675
2015 Rosenthal LS, Drake D, Alcalay RN, Babcock D, Bowman FD, Chen-Plotkin A, Dawson TM, Dewey RB, German DC, Huang X, Landin B, McAuliffe M, Petyuk VA, Scherzer CR, Hillaire-Clarke CS, et al. The NINDS Parkinson's disease biomarkers program. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26442452 DOI: 10.1002/Mds.26438  0.337
2015 Pigott K, Rick J, Xie SX, Hurtig H, Chen-Plotkin A, Duda JE, Morley JF, Chahine LM, Dahodwala N, Akhtar RS, Siderowf A, Trojanowski JQ, Weintraub D. Longitudinal study of normal cognition in Parkinson disease. Neurology. PMID 26362285 DOI: 10.1212/Wnl.0000000000002001  0.351
2015 Mata IF, Leverenz JB, Weintraub D, Trojanowski JQ, Chen-Plotkin A, Van Deerlin VM, Ritz B, Rausch R, Factor SA, Wood-Siverio C, Quinn JF, Chung KA, Peterson-Hiller AL, Goldman JG, Stebbins GT, et al. GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26296077 DOI: 10.1002/Mds.26359  0.452
2015 Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ, Gwinn K, Sutherland M, Martinez M, Heutink P, Williams NM, Hardy J, Gasser T, Brice A, Price TR, Nicolas A, ... ... Chen-Plotkin A, et al. Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study. The Lancet. Neurology. 14: 1002-9. PMID 26271532 DOI: 10.1016/S1474-4422(15)00178-7  0.317
2015 Swanson CR, Berlyand Y, Xie SX, Alcalay RN, Chahine LM, Chen-Plotkin AS. Plasma apolipoprotein A1 associates with age at onset and motor severity in early Parkinson's disease patients. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 1648-56. PMID 26207725 DOI: 10.1002/Mds.26290  0.705
2015 Fitts W, Weintraub D, Massimo L, Chahine L, Chen-Plotkin A, Duda JE, Hurtig HI, Rick J, Trojanowski JQ, Dahodwala N. Caregiver report of apathy predicts dementia in Parkinson's disease. Parkinsonism & Related Disorders. 21: 992-5. PMID 26117435 DOI: 10.1016/J.Parkreldis.2015.06.009  0.48
2015 Swanson CR, Li K, Unger TL, Gallagher MD, Van Deerlin VM, Agarwal P, Leverenz J, Roberts J, Samii A, Gross RG, Hurtig H, Rick J, Weintraub D, Trojanowski JQ, Zabetian C, ... Chen-Plotkin AS, et al. Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 805-12. PMID 25227208 DOI: 10.1002/Mds.26022  0.79
2015 Fitts W, Weintraub D, Massimo L, Chahine L, Chen-Plotkin A, Duda JE, Hurtig HI, Rick J, Trojanowski JQ, Dahodwala N. Caregiver report of apathy predicts dementia in Parkinson's disease Parkinsonism and Related Disorders. DOI: 10.1016/j.parkreldis.2015.06.009  0.445
2014 Chen-Plotkin AS. Unbiased approaches to biomarker discovery in neurodegenerative diseases. Neuron. 84: 594-607. PMID 25442938 DOI: 10.1016/j.neuron.2014.10.031  0.357
2014 van Steenoven I, Aarsland D, Hurtig H, Chen-Plotkin A, Duda JE, Rick J, Chahine LM, Dahodwala N, Trojanowski JQ, Roalf DR, Moberg PJ, Weintraub D. Conversion between mini-mental state examination, montreal cognitive assessment, and dementia rating scale-2 scores in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1809-15. PMID 25381961 DOI: 10.1002/Mds.26062  0.394
2014 Mollenhauer B, Rochester L, Chen-Plotkin A, Brooks D. What can biomarkers tell us about cognition in Parkinson's disease? Movement Disorders. 29: 622-633. PMID 24757111 DOI: 10.1002/Mds.25846  0.332
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Chen-Plotkin AS, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  0.686
2014 Chahine LM, Stern MB, Chen-Plotkin A. Blood-based biomarkers for Parkinson's disease. Parkinsonism & Related Disorders. 20: S99-103. PMID 24262199 DOI: 10.1016/S1353-8020(13)70025-7  0.331
2014 Toledo JB, Van Deerlin VM, Lee EB, Suh E, Baek Y, Robinson JL, Xie SX, McBride J, Wood EM, Schuck T, Irwin DJ, Gross RG, Hurtig H, McCluskey L, Elman L, ... ... Chen-Plotkin A, et al. A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 477-84.e1. PMID 23978324 DOI: 10.1016/J.Jalz.2013.06.003  0.621
2014 Tsuang D, Bekris L, Leverenz J, Yu C, Lopez O, Hamilton R, Bennett D, Schneider J, Buchman A, Larson EB, Crane P, Kaye J, Kramer P, Woltjer R, Trojanowski JQ, ... ... Chen-Plotkin A, et al. P4-377: A TOMM40 SNP IN APOE E4 NON-CARRIERS INCREASES RISK FOR MULTIPLE TYPES OF DEMENTIA Alzheimer's & Dementia. 10: P926-P926. DOI: 10.1016/J.Jalz.2014.07.146  0.465
2013 Busch JI, Martinez-Lage M, Ashbridge E, Grossman M, Van Deerlin VM, Hu F, Lee VM, Trojanowski JQ, Chen-Plotkin AS. Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain. Acta Neuropathologica Communications. 1: 36. PMID 24252750 DOI: 10.1186/2051-5960-1-36  0.811
2013 Wood EM, Falcone D, Suh E, Irwin DJ, Chen-Plotkin AS, Lee EB, Xie SX, Van Deerlin VM, Grossman M. Development and validation of pedigree classification criteria for frontotemporal lobar degeneration. Jama Neurology. 70: 1411-7. PMID 24081456 DOI: 10.1001/Jamaneurol.2013.3956  0.413
2013 Kang JH, Irwin DJ, Chen-Plotkin AS, Siderowf A, Caspell C, Coffey CS, Waligórska T, Taylor P, Pan S, Frasier M, Marek K, Kieburtz K, Jennings D, Simuni T, Tanner CM, et al. Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease. Jama Neurology. 70: 1277-87. PMID 23979011 DOI: 10.1001/Jamaneurol.2013.3861  0.486
2013 Yarchoan M, Louneva N, Xie SX, Swenson FJ, Hu W, Soares H, Trojanowski JQ, Lee VM, Kling MA, Shaw LM, Chen-Plotkin A, Wolk DA, Arnold SE. Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease. Journal of the Neurological Sciences. 333: 9-12. PMID 23978419 DOI: 10.1016/J.Jns.2013.05.028  0.658
2013 Chahine LM, Qiang J, Ashbridge E, Minger J, Yearout D, Horn S, Colcher A, Hurtig HI, Lee VM, Van Deerlin VM, Leverenz JB, Siderowf AD, Trojanowski JQ, Zabetian CP, Chen-Plotkin A. Clinical and biochemical differences in patients having Parkinson disease with vs without GBA mutations. Jama Neurology. 70: 852-8. PMID 23699752 DOI: 10.1001/Jamaneurol.2013.1274  0.579
2013 Qiang JK, Wong YC, Siderowf A, Hurtig HI, Xie SX, Lee VM, Trojanowski JQ, Yearout D, B Leverenz J, Montine TJ, Stern M, Mendick S, Jennings D, Zabetian C, Marek K, ... Chen-Plotkin AS, et al. Plasma apolipoprotein A1 as a biomarker for Parkinson disease. Annals of Neurology. 74: 119-27. PMID 23447138 DOI: 10.1002/Ana.23872  0.591
2013 Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Trojanowski JQ, Weintraub D, Chen-Plotkin AS, et al. APOE ε4 increases risk for dementia in pure synucleinopathies. Jama Neurology. 70: 223-8. PMID 23407718 DOI: 10.1001/Jamaneurol.2013.600  0.562
2013 Ryvkin P, Leung YY, Dragomir I, Schuck T, Schellenberg G, Arnold S, Chen-Plotkin A, Van Deerlin V, Lee V, Trojanowski J, Gregory B, Wang L. P3-064: Characterizing the Alzheimer's disease prefrontal cortex transcriptome by multiple RNA-sequencing Alzheimer's & Dementia. 9: P574-P574. DOI: 10.1016/J.Jalz.2013.05.1134  0.5
2013 Leung YY, Toledo J, Nefedov A, Polikar R, Raghavan N, Xie S, Farnum M, Schultz T, Baek Y, Lobanov V, DiBernardo A, Deerlin VV, Kling M, Chen-Plotkin A, Mailman M, et al. Identifying multi-analyte CSF biomarkers for Alzheimer’s disease in a multi-cohort study Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.059  0.659
2012 Chen-Plotkin AS, Unger TL, Gallagher MD, Bill E, Kwong LK, Volpicelli-Daley L, Busch JI, Akle S, Grossman M, Van Deerlin V, Trojanowski JQ, Lee VM. TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11213-27. PMID 22895706 DOI: 10.1523/Jneurosci.0521-12.2012  0.791
2012 Hu WT, Holtzman DM, Fagan AM, Shaw LM, Perrin R, Arnold SE, Grossman M, Xiong C, Craig-Schapiro R, Clark CM, Pickering E, Kuhn M, Chen Y, Van Deerlin VM, McCluskey L, ... ... Chen-Plotkin A, et al. Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology. 79: 897-905. PMID 22855860 DOI: 10.1212/Wnl.0B013E318266Fa70  0.692
2012 Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VM, Mackin RS, Trojanowski JQ, et al. Plasma biomarkers of depressive symptoms in older adults. Translational Psychiatry. 2: e65. PMID 22832727 DOI: 10.1038/Tp.2011.63  0.61
2012 Morley JF, Xie SX, Hurtig HI, Stern MB, Colcher A, Horn S, Dahodwala N, Duda JE, Weintraub D, Chen-Plotkin AS, Van Deerlin V, Falcone D, Siderowf A. Genetic influences on cognitive decline in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 512-8. PMID 22344634 DOI: 10.1002/Mds.24946  0.351
2012 Chahine L, Ashbridge E, Minger J, Yearout D, Qiang J, Siderowf A, Hurtig H, Zabetian C, Lee V, Van Deerlin V, Trojanowski J, Chen-Plotkin A. Clinical and Biochemical Differences between Parkinson's Disease Patients With and Without Mutations in the Glucocerebrosidase Gene (P06.072) Neurology. 78: P06.072-P06.072. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P06.072  0.562
2012 Kang JH, Chen-Plotkin A, Irwin D, Siderowf A, Caspell C, Coffey C, Taylor P, Frasier M, Marek K, Mollenhauer B, Trojanowski J, Shaw L. CSF α-synuclein, BETA-AMYLOID 1-42 and tau proteins: Relationship to clinical parameters in early Parkinson's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2013.08.089  0.428
2012 Farnum M, Baek Y, Schultz T, Nefedov A, Xie S, Leung YY, Toledo J, Raghavan N, Chen-Plotkin A, Wolk D, Polikar R, DiBernardo A, Siderowf A, Davatzikos C, Van Deerlin V, et al. P1-006: An integrated approach to the development of biomarkers for Alzheimer's disease using hospital population data Alzheimer's & Dementia. 8: P109-P109. DOI: 10.1016/J.Jalz.2012.05.281  0.524
2011 Chen-Plotkin AS, Hu WT, Siderowf A, Weintraub D, Goldmann Gross R, Hurtig HI, Xie SX, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Van Deerlin VM, Lee VM, et al. Plasma epidermal growth factor levels predict cognitive decline in Parkinson disease. Annals of Neurology. 69: 655-63. PMID 21520231 DOI: 10.1002/Ana.22271  0.683
2011 Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, et al. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Archives of Neurology. 68: 488-97. PMID 21482928 DOI: 10.1001/Archneurol.2011.53  0.719
2011 Yu Z, Zhu Y, Chen-Plotkin AS, Clay-Falcone D, McCluskey L, Elman L, Kalb RG, Trojanowski JQ, Lee VM, Van Deerlin VM, Gitler AD, Bonini NM. PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats. Plos One. 6: e17951. PMID 21479228 DOI: 10.1371/Journal.Pone.0017951  0.533
2011 Igaz LM, Kwong LK, Lee EB, Chen-Plotkin A, Swanson E, Unger T, Malunda J, Xu Y, Winton MJ, Trojanowski JQ, Lee VM. Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. The Journal of Clinical Investigation. 121: 726-38. PMID 21206091 DOI: 10.1172/Jci44867  0.778
2011 Vass R, Ashbridge E, Geser F, Hu WT, Grossman M, Clay-Falcone D, Elman L, McCluskey L, Lee VM, Van Deerlin VM, Trojanowski JQ, Chen-Plotkin AS. Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis. Acta Neuropathologica. 121: 373-80. PMID 21104415 DOI: 10.1007/S00401-010-0782-Y  0.648
2011 Arnold S, Xie SX, Leung Y, Kim E, Kling M, Wilson R, Bennett D, Hu W, Mackin S, Grossman M, Chen-Plotkin A, Wolk D, Lee V, Trojanowski J, Shaw L. P2-017: Biochemical Biomarkers of Depressive Symptoms in ADNI Alzheimer's & Dementia. 7: S312-S312. DOI: 10.1016/J.Jalz.2011.05.907  0.578
2011 Hu WT, Holtzman D, Clark C, Grossman M, Karlawish J, Fagan A, Lee V, Swenson F, Craig-Schapiro R, Perrin RJ, Soares H, Trojanowski J, Xiong C, Morris J, Shaw L, ... ... Chen-Plotkin A, et al. P1-089: Plasma multianalyte profiling of mild cognitive impairment and Alzheimer's disease in two academic centers and the Alzheimer's Disease Neuroimaging Initiative Alzheimer's & Dementia. 7: S138-S138. DOI: 10.1016/J.Jalz.2011.05.368  0.687
2010 Hu WT, Chen-Plotkin A, Grossman M, Arnold SE, Clark CM, Shaw LM, McCluskey L, Elman L, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Novel CSF biomarkers for frontotemporal lobar degenerations. Neurology. 75: 2079-86. PMID 21048198 DOI: 10.1016/J.Jalz.2010.05.253  0.651
2010 Cao K, Chen-Plotkin AS, Plotkin JB, Wang LS. Age-correlated gene expression in normal and neurodegenerative human brain tissues. Plos One. 5. PMID 20927326 DOI: 10.1371/Journal.Pone.0013098  0.308
2010 Elden AC, Kim HJ, Hart MP, Chen-Plotkin AS, Johnson BS, Fang X, Armakola M, Geser F, Greene R, Lu MM, Padmanabhan A, Clay-Falcone D, McCluskey L, Elman L, Juhr D, et al. Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature. 466: 1069-75. PMID 20740007 DOI: 10.1038/Nature09320  0.523
2010 Siderowf A, Xie SX, Hurtig H, Weintraub D, Duda J, Chen-Plotkin A, Shaw LM, Van Deerlin V, Trojanowski JQ, Clark C. CSF amyloid {beta} 1-42 predicts cognitive decline in Parkinson disease. Neurology. 75: 1055-61. PMID 20720189 DOI: 10.1212/Wnl.0B013E3181F39A78  0.463
2010 Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Biomarker discovery for Alzheimer's disease, frontotemporal lobar degeneration, and Parkinson's disease. Acta Neuropathologica. 120: 385-99. PMID 20652578 DOI: 10.1007/S00401-010-0723-9  0.704
2010 Chen-Plotkin AS, Lee VM, Trojanowski JQ. TAR DNA-binding protein 43 in neurodegenerative disease. Nature Reviews. Neurology. 6: 211-20. PMID 20234357 DOI: 10.1038/Nrneurol.2010.18  0.582
2010 Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, Pickering E, Kuhn M, Chen Y, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, et al. Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment. Acta Neuropathologica. 119: 669-78. PMID 20232070 DOI: 10.1007/S00401-010-0667-0  0.66
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  0.685
2010 Yu CE, Bird TD, Bekris LM, Montine TJ, Leverenz JB, Steinbart E, Galloway NM, Feldman H, Woltjer R, Miller CA, Wood EM, Grossman M, McCluskey L, Clark CM, Neumann M, ... ... Chen-Plotkin A, et al. The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. Archives of Neurology. 67: 161-70. PMID 20142524 DOI: 10.1001/Archneurol.2009.328  0.487
2010 Chen-Plotkin AS, Xiao J, Geser F, Martinez-Lage M, Grossman M, Unger T, Wood EM, Van Deerlin VM, Trojanowski JQ, Lee VM. Brain progranulin expression in GRN-associated frontotemporal lobar degeneration. Acta Neuropathologica. 119: 111-22. PMID 19649643 DOI: 10.1007/S00401-009-0576-2  0.678
2010 Hu WT, Grossman M, Chen-Plotkin A, Arnold SE, Clark CM, Shaw LM, Lee VM, Soares HD, Trojanowski JQ. O1-07-05: Novel CSF biomarkers for frontotemporal lobar degenerations Alzheimer's & Dementia. 6: S84-S84. DOI: 10.1016/j.jalz.2010.05.253  0.524
2010 Soares H, Hu W, Grossman M, Clark C, Pickering E, Chen Y, Kuhn M, Chen-Plotkin A, Arnold S, Shaw L, Lee VM, Swenson F, Trojanowski JQ. P2-093: Multiplex plasma panels as screening tools in Alzheimer's disease. Alzheimer's & Dementia. 6: S340-S340. DOI: 10.1016/J.Jalz.2010.05.1139  0.595
2009 Igaz LM, Kwong LK, Chen-Plotkin A, Winton MJ, Unger TL, Xu Y, Neumann M, Trojanowski JQ, Lee VM. Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies. The Journal of Biological Chemistry. 284: 8516-24. PMID 19164285 DOI: 10.1074/Jbc.M809462200  0.789
2008 Van Deerlin VM, Leverenz JB, Bekris LM, Bird TD, Yuan W, Elman LB, Clay D, Wood EM, Chen-Plotkin AS, Martinez-Lage M, Steinbart E, McCluskey L, Grossman M, Neumann M, Wu IL, et al. TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis. The Lancet. Neurology. 7: 409-16. PMID 18396105 DOI: 10.1016/S1474-4422(08)70071-1  0.682
2008 Chen-Plotkin AS, Geser F, Plotkin JB, Clark CM, Kwong LK, Yuan W, Grossman M, Van Deerlin VM, Trojanowski JQ, Lee VM. Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration. Human Molecular Genetics. 17: 1349-62. PMID 18223198 DOI: 10.1093/Hmg/Ddn023  0.559
2008 Chen-Plotkin AS, Yuan W, Anderson C, McCarty Wood E, Hurtig HI, Clark CM, Miller BL, Lee VM, Trojanowski JQ, Grossman M, Van Deerlin VM. Corticobasal syndrome and primary progressive aphasia as manifestations of LRRK2 gene mutations. Neurology. 70: 521-7. PMID 17914064 DOI: 10.1212/01.Wnl.0000280574.17166.26  0.571
2006 Chen-Plotkin AS, Sadri-Vakili G, Yohrling GJ, Braveman MW, Benn CL, Glajch KE, DiRocco DP, Farrell LA, Krainc D, Gines S, MacDonald ME, Cha JH. Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease. Neurobiology of Disease. 22: 233-41. PMID 16442295 DOI: 10.1016/J.Nbd.2005.11.001  0.77
2004 Braveman MW, Chen-Plotkin AS, Yohrling GJ, Cha JH. Chromatin immunoprecipitation technique for study of transcriptional dysregulation in intact mouse brain. Methods in Molecular Biology (Clifton, N.J.). 277: 261-76. PMID 15201461 DOI: 10.1385/1-59259-804-8:261  0.721
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