Christian Vaisse, M.D., Ph.D. - Publications

Affiliations: 
Diabetes Center University of California, San Francisco, San Francisco, CA 
Area:
Genetics of Obesity

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Yulyaningsih E, Rudenko IA, Valdearcos M, Dahlén E, Vagena E, Chan A, Alvarez-Buylla A, Vaisse C, Koliwad SK, Xu AW. Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier. Cell Reports. 19: 2257-2271. PMID 28614713 DOI: 10.1016/j.celrep.2017.05.060  0.32
2015 Mishra S, Harris TB, Hsueh WC, Hue T, Leak TS, Li R, Mehta M, Vaisse C, Sahyoun NR. The Association of Serum Leptin with Mortality in Older Adults. Plos One. 10: e0140763. PMID 26473487 DOI: 10.1371/journal.pone.0140763  0.96
2014 Evans DS, Calton MA, Kim MJ, Kwok PY, Miljkovic I, Harris T, Koster A, Liu Y, Tranah GJ, Ahituv N, Hsueh WC, Vaisse C. Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions. Plos One. 9: e96805. PMID 24820477 DOI: 10.1371/journal.pone.0096805  0.96
2014 Kim MJ, Oksenberg N, Hoffmann TJ, Vaisse C, Ahituv N. Functional characterization of SIM1-associated enhancers. Human Molecular Genetics. 23: 1700-8. PMID 24203700 DOI: 10.1093/hmg/ddt559  0.96
2014 Aslan IR, Ranadive SA, Valle I, Kollipara S, Noble JA, Vaisse C. The melanocortin system and insulin resistance in humans: insights from a patient with complete POMC deficiency and type 1 diabetes mellitus. International Journal of Obesity (2005). 38: 148-51. PMID 23649472 DOI: 10.1038/ijo.2013.53  0.96
2012 Ersoy BA, Pardo L, Zhang S, Thompson DA, Millhauser G, Govaerts C, Vaisse C. Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR. Nature Chemical Biology. 8: 725-30. PMID 22729149 DOI: 10.1038/nchembio.1008  0.96
2011 Swarbrick MM, Evans DS, Valle MI, Favre H, Wu SH, Njajou OT, Li R, Zmuda JM, Miljkovic I, Harris TB, Kwok PY, Vaisse C, Hsueh WC. Replication and extension of association between common genetic variants in SIM1 and human adiposity. Obesity (Silver Spring, Md.). 19: 2394-403. PMID 21512513 DOI: 10.1038/oby.2011.79  0.96
2011 Aslan IR, Campos GM, Calton MA, Evans DS, Merriman RB, Vaisse C. Weight loss after Roux-en-Y gastric bypass in obese patients heterozygous for MC4R mutations. Obesity Surgery. 21: 930-4. PMID 20957447 DOI: 10.1007/s11695-010-0295-8  0.96
2011 Ionova-Martin SS, Wade JM, Tang S, Shahnazari M, Ager JW, Lane NE, Yao W, Alliston T, Vaisse C, Ritchie RO. Changes in cortical bone response to high-fat diet from adolescence to adulthood in mice. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 22: 2283-93. PMID 20941479 DOI: 10.1007/s00198-010-1432-x  0.96
2011 Aslan IR, Ranadive SA, Ersoy BA, Rogers SJ, Lustig RH, Vaisse C. Bariatric surgery in a patient with complete MC4R deficiency. International Journal of Obesity (2005). 35: 457-61. PMID 20733581 DOI: 10.1038/ijo.2010.168  0.96
2010 Ionova-Martin SS, Do SH, Barth HD, Szadkowska M, Porter AE, Ager JW, Ager JW, Alliston T, Vaisse C, Ritchie RO. Reduced size-independent mechanical properties of cortical bone in high-fat diet-induced obesity. Bone. 46: 217-25. PMID 19853069 DOI: 10.1016/j.bone.2009.10.015  0.96
2009 Bromberg Y, Overton J, Vaisse C, Leibel RL, Rost B. In silico mutagenesis: a case study of the melanocortin 4 receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3059-69. PMID 19417090 DOI: 10.1096/fj.08-127530  0.96
2009 Calton MA, Vaisse C. Narrowing down the role of common variants in the genetic predisposition to obesity. Genome Medicine. 1: 31. PMID 19341502 DOI: 10.1186/gm31  0.96
2009 Ranadive SA, Ersoy B, Favre H, Cheung CC, Rosenthal SM, Miller WL, Vaisse C. Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus. Clinical Endocrinology. 71: 388-93. PMID 19170711 DOI: 10.1111/j.1365-2265.2008.03513.x  0.96
2009 Calton MA, Ersoy BA, Zhang S, Kane JP, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R, Ahituv N, Vaisse C. Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Human Molecular Genetics. 18: 1140-7. PMID 19091795 DOI: 10.1093/hmg/ddn431  0.96
2008 Ranadive SA, Vaisse C. Lessons from extreme human obesity: monogenic disorders. Endocrinology and Metabolism Clinics of North America. 37: 733-51, x. PMID 18775361 DOI: 10.1016/j.ecl.2008.07.003  0.96
2008 Clément K, Dubern B, Mencarelli M, Czernichow P, Ito S, Wakamatsu K, Barsh GS, Vaisse C, Leger J. Unexpected endocrine features and normal pigmentation in a young adult patient carrying a novel homozygous mutation in the POMC gene. The Journal of Clinical Endocrinology and Metabolism. 93: 4955-62. PMID 18765507 DOI: 10.1210/jc.2008-1164  0.96
2008 Louet JF, Smith SB, Gautier JF, Molokhia M, Virally ML, Kevorkian JP, Guillausseau PJ, Vexiau P, Charpentier G, German MS, Vaisse C, Urbanek M, Mauvais-Jarvis F. Gender and neurogenin3 influence the pathogenesis of ketosis-prone diabetes. Diabetes, Obesity & Metabolism. 10: 912-20. PMID 18093211 DOI: 10.1111/j.1463-1326.2007.00830.x  0.96
2008 Dubern B, Lubrano-Berthelier C, Mencarelli M, Ersoy B, Frelut ML, Bouglé D, Costes B, Simon C, Tounian P, Vaisse C, Clement K. Mutational analysis of the pro-opiomelanocortin gene in French obese children led to the identification of a novel deleterious heterozygous mutation located in the alpha-melanocyte stimulating hormone domain. Pediatric Research. 63: 211-6. PMID 18091355 DOI: 10.1203/PDR.0b013e31815ed62b  0.96
2007 Srinivasan S, Santiago P, Lubrano C, Vaisse C, Conklin BR. Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo. Plos One. 2: e668. PMID 17668051 DOI: 10.1371/journal.pone.0000668  0.96
2007 Ahituv N, Kavaslar N, Schackwitz W, Ustaszewska A, Martin J, Hebert S, Doelle H, Ersoy B, Kryukov G, Schmidt S, Yosef N, Ruppin E, Sharan R, Vaisse C, Sunyaev S, et al. Medical sequencing at the extremes of human body mass. American Journal of Human Genetics. 80: 779-91. PMID 17357083 DOI: 10.1086/513471  0.96
2006 Lubrano-Berthelier C, Dubern B, Lacorte JM, Picard F, Shapiro A, Zhang S, Bertrais S, Hercberg S, Basdevant A, Clement K, Vaisse C. Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating. The Journal of Clinical Endocrinology and Metabolism. 91: 1811-8. PMID 16507637 DOI: 10.1210/jc.2005-1411  0.96
2005 Swarbrick MM, Waldenmaier B, Pennacchio LA, Lind DL, Cavazos MM, Geller F, Merriman R, Ustaszewska A, Malloy M, Scherag A, Hsueh WC, Rief W, Mauvais-Jarvis F, Pullinger CR, Kane JP, ... ... Vaisse C, et al. Lack of support for the association between GAD2 polymorphisms and severe human obesity. Plos Biology. 3: e315. PMID 16122350 DOI: 10.1371/journal.pbio.0030315  0.96
2005 Govaerts C, Srinivasan S, Shapiro A, Zhang S, Picard F, Clement K, Lubrano-Berthelier C, Vaisse C. Obesity-associated mutations in the melanocortin 4 receptor provide novel insights into its function. Peptides. 26: 1909-19. PMID 16083993 DOI: 10.1016/j.peptides.2004.11.042  0.96
2005 Sobngwi E, Gautier JF, Kevorkian JP, Villette JM, Riveline JP, Zhang S, Vexiau P, Leal SM, Vaisse C, Mauvais-Jarvis F. High prevalence of glucose-6-phosphate dehydrogenase deficiency without gene mutation suggests a novel genetic mechanism predisposing to ketosis-prone diabetes. The Journal of Clinical Endocrinology and Metabolism. 90: 4446-51. PMID 15914531 DOI: 10.1210/jc.2004-2545  0.96
2005 Picard F, Robin S, Lavielle M, Vaisse C, Daudin JJ. A statistical approach for array CGH data analysis. Bmc Bioinformatics. 6: 27. PMID 15705208 DOI: 10.1186/1471-2105-6-27  0.96
2004 Mauvais-Jarvis F, Smith SB, Le May C, Leal SM, Gautier JF, Molokhia M, Riveline JP, Rajan AS, Kevorkian JP, Zhang S, Vexiau P, German MS, Vaisse C. PAX4 gene variations predispose to ketosis-prone diabetes. Human Molecular Genetics. 13: 3151-9. PMID 15509590 DOI: 10.1093/hmg/ddh341  0.96
2004 Srinivasan S, Lubrano-Berthelier C, Govaerts C, Picard F, Santiago P, Conklin BR, Vaisse C. Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans. The Journal of Clinical Investigation. 114: 1158-64. PMID 15489963 DOI: 10.1172/JCI21927  0.96
2004 Lubrano-Berthelier C, Le Stunff C, Bougnères P, Vaisse C. A homozygous null mutation delineates the role of the melanocortin-4 receptor in humans. The Journal of Clinical Endocrinology and Metabolism. 89: 2028-32. PMID 15126516 DOI: 10.1210/jc.2003-031993  0.96
2004 Mauvais-Jarvis F, Sobngwi E, Porcher R, Riveline JP, Kevorkian JP, Vaisse C, Charpentier G, Guillausseau PJ, Vexiau P, Gautier JF. Ketosis-prone type 2 diabetes in patients of sub-Saharan African origin: clinical pathophysiology and natural history of beta-cell dysfunction and insulin resistance. Diabetes. 53: 645-53. PMID 14988248 DOI: 10.2337/diabetes.53.3.645  0.96
2003 Lubrano-Berthelier C, Cavazos M, Le Stunff C, Haas K, Shapiro A, Zhang S, Bougneres P, Vaisse C. The human MC4R promoter: characterization and role in obesity. Diabetes. 52: 2996-3000. PMID 14633862 DOI: 10.2337/diabetes.52.12.2996  0.96
2003 Srinivasan S, Vaisse C, Conklin BR. Engineering the melanocortin-4 receptor to control G(s) signaling in vivo. Annals of the New York Academy of Sciences. 994: 225-32. PMID 12851320  0.96
2003 Lubrano-Berthelier C, Cavazos M, Dubern B, Shapiro A, Stunff CL, Zhang S, Picart F, Govaerts C, Froguel P, Bougneres P, Clement K, Vaisse C. Molecular genetics of human obesity-associated MC4R mutations. Annals of the New York Academy of Sciences. 994: 49-57. PMID 12851297  0.96
2003 Swarbrick MM, Vaisse C. Emerging trends in the search for genetic variants predisposing to human obesity. Current Opinion in Clinical Nutrition and Metabolic Care. 6: 369-75. PMID 12806208 DOI: 10.1097/01.mco.0000078997.96795.03  0.96
2003 Lubrano-Berthelier C, Durand E, Dubern B, Shapiro A, Dazin P, Weill J, Ferron C, Froguel P, Vaisse C. Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations. Human Molecular Genetics. 12: 145-53. PMID 12499395 DOI: 10.1093/hmg/ddg016  0.96
2002 Cummings DE, Clement K, Purnell JQ, Vaisse C, Foster KE, Frayo RS, Schwartz MW, Basdevant A, Weigle DS. Elevated plasma ghrelin levels in Prader Willi syndrome. Nature Medicine. 8: 643-4. PMID 12091883 DOI: 10.1038/nm0702-643  0.96
2000 Mueller MD, Vigne JL, Vaisse C, Taylor RN. Glycodelin: a pane in the implantation window. Seminars in Reproductive Medicine. 18: 289-98. PMID 11299967 DOI: 10.1055/s-2000-12566  0.96
2000 Vaisse C, Clement K, Durand E, Hercberg S, Guy-Grand B, Froguel P. Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. The Journal of Clinical Investigation. 106: 253-62. PMID 10903341 DOI: 10.1172/JCI9238  0.96
2000 Navas MA, Vaisse C, Boger S, Heimesaat M, Kollee LA, Stoffel M. The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis. Human Heredity. 50: 370-81. PMID 10899756  0.96
2000 Clement K, Hercberg S, Passinge B, Galan P, Varroud-Vial M, Shuldiner AR, Beamer BA, Charpentier G, Guy-Grand B, Froguel P, Vaisse C. The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 24: 391-3. PMID 10757637  0.96
1999 Bruneau G, Vaisse C, Caraty A, Monget P. Leptin: A key for reproduction | La leptine: Une cle pour la reproduction Medecine/Sciences. 15: 191-196.  0.96
1998 Taylor RN, Savouret JF, Vaisse C, Vigne JL, Ryan I, Hornung D, Seppälä M, Milgrom E. Promegestone (R5020) and mifepristone (RU486) both function as progestational agonists of human glycodelin gene expression in isolated human epithelial cells. The Journal of Clinical Endocrinology and Metabolism. 83: 4006-12. PMID 9814484 DOI: 10.1210/jcem.83.11.5214  0.96
1998 Vaisse C, Clement K, Guy-Grand B, Froguel P. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nature Genetics. 20: 113-4. PMID 9771699 DOI: 10.1038/2407  0.96
1998 Clément K, Vaisse C, Lahlou N, Cabrol S, Pelloux V, Cassuto D, Gourmelen M, Dina C, Chambaz J, Lacorte JM, Basdevant A, Bougnères P, Lebouc Y, Froguel P, Guy-Grand B. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature. 392: 398-401. PMID 9537324 DOI: 10.1038/32911  0.96
1997 Vaisse C, Kim J, Espinosa R, Le Beau MM, Stoffel M. Pancreatic islet expression studies and polymorphic DNA markers in the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6. Diabetes. 46: 1364-7. PMID 9231664  0.96
1996 Vaisse C, Halaas JL, Horvath CM, Darnell JE, Stoffel M, Friedman JM. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nature Genetics. 14: 95-7. PMID 8782827 DOI: 10.1038/ng0996-95  0.96
1995 Hager J, Hansen L, Vaisse C, Vionnet N, Philippi A, Poller W, Velho G, Carcassi C, Contu L, Julier C. A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus. Nature Genetics. 9: 299-304. PMID 7773293 DOI: 10.1038/ng0395-299  0.96
1995 Clément K, Vaisse C, Manning BS, Basdevant A, Guy-Grand B, Ruiz J, Silver KD, Shuldiner AR, Froguel P, Strosberg AD. Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. The New England Journal of Medicine. 333: 352-4. PMID 7609752 DOI: 10.1056/NEJM199508103330605  0.96
1995 Ruiz J, Blanché H, James RW, Garin MC, Vaisse C, Charpentier G, Cohen N, Morabia A, Passa P, Froguel P. Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes. Lancet. 346: 869-72. PMID 7564671 DOI: 10.1016/S0140-6736(95)92709-3  0.96
1991 Van Cong N, Vaisse C, Gross MS, Slim R, Milgrom E, Bernheim A. The human placental protein 14 (PP14) gene is localized on chromosome 9q34. Human Genetics. 86: 515-8. PMID 2016092 DOI: 10.1007/BF00194645  0.96
1990 Vaisse C, Atger M, Potier B, Milgrom E. Human placental protein 14 gene: sequence and characterization of a short duplication. Dna and Cell Biology. 9: 401-13. PMID 2206398  0.96
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