| Year |
Citation |
Score |
| 2025 |
Nguyen T, Decker AM, Barrus DG, Song CH, Liu J, Gamage TF, Harris DL, Li JX, Zhang Y. Development of Squaramides as Allosteric Modulators of the CB Receptor: Synthesis, Computational Studies, Biological Characterization, and Effects against Cocaine-Induced Behavioral Sensitization and Reinstatement in Rats. Journal of Medicinal Chemistry. PMID 40198119 DOI: 10.1021/acs.jmedchem.5c00383 |
0.323 |
|
| 2024 |
Wiley JL, Marusich JA, Blough BE, Namjoshi O, Brackeen M, Akinfiresoye LR, Walker TD, Prioleau C, Barrus DG, Gamage TF. Evaluation of cannabimimetic effects of selected minor cannabinoids and Terpenoids in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 132: 110984. PMID 38417478 DOI: 10.1016/j.pnpbp.2024.110984 |
0.57 |
|
| 2022 |
Marusich JA, Gamage TF, Zhang Y, Akinfiresoye LR, Wiley JL. In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonists. Pharmacology, Biochemistry, and Behavior. 220: 173467. PMID 36154844 DOI: 10.1016/j.pbb.2022.173467 |
0.634 |
|
| 2022 |
Finlay DB, Nguyen T, Gamage TF, Chen S, Barrus DG, Patel PR, Thomas BF, Wiley JL, Zhang Y, Glass M. Exploring determinants of agonist efficacy at the CB1 cannabinoid receptor: Analogues of the synthetic cannabinoid receptor agonist EG-018. Pharmacology Research & Perspectives. 10: e00901. PMID 35041297 DOI: 10.1002/prp2.901 |
0.715 |
|
| 2021 |
Nguyen T, Gamage TF, Decker AM, Finlay DB, Langston TL, Barrus D, Glass M, Harris DL, Zhang Y. Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids. Bioorganic & Medicinal Chemistry. 41: 116215. PMID 34015703 DOI: 10.1016/j.bmc.2021.116215 |
0.335 |
|
| 2020 |
Wiley JL, Barrus DG, Farquhar CE, Lefever TW, Gamage TF. Sex, species and age: Effects of rodent demographics on the pharmacology of ∆-tetrahydrocanabinol. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110064. PMID 32810571 DOI: 10.1016/J.Pnpbp.2020.110064 |
0.624 |
|
| 2020 |
Gamage TF, Barrus DG, Kevin RC, Finlay DB, Lefever TW, Patel PR, Grabenauer MA, Glass M, McGregor IS, Wiley JL, Thomas BF. In vitro and in vivo pharmacological evaluation of the synthetic cannabinoid receptor agonist EG-018. Pharmacology, Biochemistry, and Behavior. 172918. PMID 32247816 DOI: 10.1016/J.Pbb.2020.172918 |
0.755 |
|
| 2019 |
Nguyen T, Gamage T, Decker AM, Barrus D, Langston TL, Li JX, Thomas BF, Zhang Y. Synthesis and Pharmacological Evaluation of 1-Phenyl-3-Thiophenylurea Derivatives as Cannabinoid Type-1 Receptor Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31596583 DOI: 10.1021/Acs.Jmedchem.9B01161 |
0.638 |
|
| 2019 |
Kevin RC, Kovach AL, Lefever TW, Gamage TF, Wiley JL, McGregor IS, Thomas BF. Toxic by design? Formation of thermal degradants and cyanide from carboxamide-type synthetic cannabinoids CUMYL-PICA, 5F-CUMYL-PICA, AMB-FUBINACA, MDMB-FUBINACA, NNEI, and MN-18 during exposure to high temperatures. Forensic Toxicology. 37: 17-26. PMID 30705707 DOI: 10.1007/S11419-018-0430-0 |
0.63 |
|
| 2018 |
Gamage TF, Farquhar CE, McKinnie RJ, Kevin RC, McGregor IS, Trudell M, Wiley JL, Thomas BF. Synthetic cannabinoid hydroxypentyl metabolites retain efficacy at human cannabinoid receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 30552295 DOI: 10.1124/Jpet.118.254425 |
0.728 |
|
| 2018 |
Farquhar CE, Breivogel CS, Gamage TF, Gay EA, Thomas BF, Craft RM, Wiley JL. Sex, THC, and hormones: Effects on density and sensitivity of CB cannabinoid receptors in rats. Drug and Alcohol Dependence. 194: 20-27. PMID 30391834 DOI: 10.1016/J.Drugalcdep.2018.09.018 |
0.674 |
|
| 2018 |
Nguyen T, Gamage TF, Decker AM, German N, Langston TL, Farquhar CE, Kenakin TP, Wiley JL, Thomas BF, Zhang Y. Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation. Acs Chemical Neuroscience. PMID 30188693 DOI: 10.1021/Acschemneuro.8B00396 |
0.711 |
|
| 2018 |
Gamage TF, Farquhar CE, Lefever TW, Marusich JA, Kevin RC, McGregor IS, Wiley JL, Thomas BF. Molecular and behavioral pharmacological characterization of abused synthetic cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-fluoro-CUMYL-PICA. The Journal of Pharmacology and Experimental Therapeutics. PMID 29549157 DOI: 10.1124/Jpet.117.246983 |
0.742 |
|
| 2017 |
Kevin RC, Lefever TW, Snyder RW, Patel PR, Gamage TF, Fennell TR, Wiley JL, McGregor IS, Thomas BF. Kinetic and metabolic profiles of synthetic cannabinoids NNEI and MN-18. Drug Testing and Analysis. PMID 28834241 DOI: 10.1002/Dta.2262 |
0.666 |
|
| 2017 |
Gamage TF, Farquhar CE, Lefever TW, Thomas BF, Nguyen T, Zhang Y, Wiley JL. The great divide: Separation between in vitro and in vivo effects of PSNCBAM-based CB1 receptor allosteric modulators. Neuropharmacology. PMID 28803965 DOI: 10.1016/J.Neuropharm.2017.08.008 |
0.748 |
|
| 2017 |
Nguyen T, German N, Decker AM, Langston TL, Gamage TF, Farquhar CE, Li JX, Wiley JL, Thomas BF, Zhang Y. Novel Diarylurea Based Allosteric Modulators of the Cannabinoid CB1 Receptor: Evaluation of Importance of 6-Pyrrolidinylpyridinyl Substitution. Journal of Medicinal Chemistry. PMID 28792219 DOI: 10.1021/Acs.Jmedchem.7B00707 |
0.731 |
|
| 2017 |
Thomas BF, Lefever TW, Cortes RA, Kovach AL, Cox AO, Patel PR, Pollard GT, Marusich JA, Kevin RA, Gamage TF, Wiley JL. Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. The Journal of Pharmacology and Experimental Therapeutics. PMID 28087785 DOI: 10.1124/Jpet.116.238717 |
0.704 |
|
| 2016 |
Gamage TF, Anderson JC, Abood ME. CB1 allosteric modulator Org27569 is an antagonist/inverse agonist of ERK1/2 signaling. Cannabis and Cannabinoid Research. 1: 272-280. PMID 28660254 DOI: 10.1089/can.2016.0028 |
0.611 |
|
| 2016 |
Meza-Aviña ME, Lingerfelt MA, Console-Bram LM, Gamage TF, Sharir H, Gettys KE, Hurst DP, Kotsikorou E, Shore DM, Caron MG, Rao N, Barak LS, Abood ME, Reggio PH, Croatt MP. Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones. Bioorganic & Medicinal Chemistry Letters. PMID 26916440 DOI: 10.1016/J.Bmcl.2016.02.030 |
0.619 |
|
| 2015 |
Gamage TF, Ignatowska-Jankowska BM, Muldoon PP, Cravatt BF, Damaj MI, Lichtman AH. Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice. Drug and Alcohol Dependence. 146: 7-16. PMID 25479915 DOI: 10.1016/J.Drugalcdep.2014.11.015 |
0.728 |
|
| 2014 |
Gamage TF, Ignatowska-Jankowska BM, Wiley JL, Abdelrahman M, Trembleau L, Greig IR, Thakur GA, Tichkule R, Poklis J, Ross RA, Pertwee RG, Lichtman AH. In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. Behavioural Pharmacology. 25: 182-5. PMID 24603340 DOI: 10.1097/Fbp.0000000000000027 |
0.794 |
|
| 2013 |
Ramesh D, Gamage TF, Vanuytsel T, Owens RA, Abdullah RA, Niphakis MJ, Shea-Donohue T, Cravatt BF, Lichtman AH. Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1039-49. PMID 23303065 DOI: 10.1038/Npp.2012.269 |
0.739 |
|
| 2012 |
Wise LE, Premaratne ID, Gamage TF, Lichtman AH, Hughes LD, Harris LS, Aceto MD. l-theanine attenuates abstinence signs in morphine-dependent rhesus monkeys and elicits anxiolytic-like activity in mice. Pharmacology, Biochemistry, and Behavior. 103: 245-52. PMID 22935630 DOI: 10.1016/J.Pbb.2012.08.008 |
0.704 |
|
| 2012 |
Gamage TF, Lichtman AH. The endocannabinoid system: role in energy regulation. Pediatric Blood & Cancer. 58: 144-8. PMID 22076835 DOI: 10.1002/Pbc.23367 |
0.475 |
|
| 2012 |
Vann RE, Walentiny DM, Burston JJ, Tobey KM, Gamage TF, Wiley JL. Enhancement of the behavioral effects of endogenous and exogenous cannabinoid agonists by phenylmethyl sulfonyl fluoride. Neuropharmacology. 62: 1019-27. PMID 22051632 DOI: 10.1016/J.Neuropharm.2011.10.011 |
0.772 |
|
| 2011 |
Walentiny DM, Gamage TF, Warner JA, Nguyen TK, Grainger DB, Wiley JL, Vann RE. The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. European Journal of Pharmacology. 656: 63-7. PMID 21300050 DOI: 10.1016/J.Ejphar.2011.01.056 |
0.76 |
|
| 2010 |
Jackson KJ, Marks MJ, Vann RE, Chen X, Gamage TF, Warner JA, Damaj MI. Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice. The Journal of Pharmacology and Experimental Therapeutics. 334: 137-46. PMID 20400469 DOI: 10.1124/Jpet.110.165738 |
0.319 |
|
| 2008 |
Vann RE, Gamage TF, Warner JA, Marshall EM, Taylor NL, Martin BR, Wiley JL. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug and Alcohol Dependence. 94: 191-8. PMID 18206320 DOI: 10.1016/J.Drugalcdep.2007.11.017 |
0.665 |
|
| 2006 |
Wright MJ, Vann RE, Gamage TF, Damaj MI, Wiley JL. Comparative effects of dextromethorphan and dextrorphan on nicotine discrimination in rats. Pharmacology, Biochemistry, and Behavior. 85: 507-13. PMID 17112574 DOI: 10.1016/J.Pbb.2006.09.020 |
0.603 |
|
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