Aron H. Lichtman, PhD - Publications

Pharmacology and Toxicology Virginia Commonwealth University, Richmond, VA, United States 
Endocannabinoid system

207 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hermes DJ, Jacobs IR, Key MC, League AF, Yadav-Samudrala BJ, Xu C, McLane VD, Nass SR, Jiang W, Meeker RB, Ignatowska-Jankowska BM, Lichtman AH, Li Z, Wu Z, Yuan H, et al. Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids. Journal of Neuroinflammation. 17: 345. PMID 33208151 DOI: 10.1186/s12974-020-01971-6  0.8
2020 Ayoub SM, Smoum R, Farag M, Atwal H, Collins SA, Rock EM, Limebeer CL, Piscitelli F, Iannotti FA, Lichtman AH, Leri F, Di Marzo V, Mechoulam R, Parker LA. Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats. Psychopharmacology. PMID 32556401 DOI: 10.1007/s00213-020-05570-4  0.72
2020 Muldoon PP, Akinola LS, Schlosburg JE, Lichtman AH, Sim-Selley LJ, Mahadevan A, Cravatt BF, Damaj MI. Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice. Neuropharmacology. 108170. PMID 32479813 DOI: 10.1016/j.neuropharm.2020.108170  1
2020 Ulker E, Caillaud M, Patel T, White A, Rashid D, Alqasem M, Lichtman AH, Bryant CD, Damaj MI. C57BL/6 Substrain Differences in Formalin-Induced Pain-Like Behavioral Responses. Behavioural Brain Research. 112698. PMID 32428630 DOI: 10.1016/j.bbr.2020.112698  0.76
2020 Mock ED, Mustafa M, Gunduz-Cinar O, Cinar R, Petrie GN, Kantae V, Di X, Ogasawara D, Varga ZV, Paloczi J, Miliano C, Donvito G, van Esbroeck ACM, van der Gracht AMF, Kotsogianni I, ... ... Lichtman AH, et al. Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice. Nature Chemical Biology. PMID 32393901 DOI: 10.1038/s41589-020-0528-7  0.96
2020 Schurman LD, Lu D, Kendall DA, Howlett AC, Lichtman AH. Molecular Mechanism and Cannabinoid Pharmacology. Handbook of Experimental Pharmacology. PMID 32236882 DOI: 10.1007/164_2019_298  0.76
2020 Piscitelli F, Guida F, Luongo L, Iannotti FA, Boccella S, Verde R, Lauritano A, Imperatore R, Smoum R, Cristino L, Lichtman AH, Parker LA, Mechoulam R, Maione S, Di Marzo V. Protective effects of N-oleoylglycine in a mouse model of mild traumatic brain injury. Acs Chemical Neuroscience. PMID 32017529 DOI: 10.1021/acschemneuro.9b00633  0.72
2019 Mustafa M, Donvito G, Moncayo L, Swafford A, Poklis J, Grauer R, Olszewska T, Kendall DA, Lu D, Lichtman AH. In vivo evaluation of the CB allosteric modulator LDK1258 reveals CB-receptor independent behavioral effects. Pharmacology, Biochemistry, and Behavior. 172840. PMID 31899221 DOI: 10.1016/j.pbb.2019.172840  0.72
2019 Rock EM, Ayoub SM, Limebeer CL, Gene A, Wills KL, DeVuono MV, Smoum R, Di Marzo V, Lichtman AH, Mechoulam R, Parker LA. Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine. Psychopharmacology. PMID 31712968 DOI: 10.1007/s00213-019-05373-2  0.72
2019 Xi ZX, Muldoon P, Wang XF, Bi GH, Damaj MI, Lichtman AH, Pertwee RG, Gardner EL. Δ -Tetrahydrocannabivarin has potent anti-nicotine effects in multiple rodent models of nicotine dependence. British Journal of Pharmacology. PMID 31454413 DOI: 10.1111/bph.14844  0.76
2019 Jacobs IR, Xu C, Hermes DJ, League AF, Xu C, Nath B, Jiang W, Niphakis MJ, Cravatt BF, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Inhibitory Control Deficits Associated with Upregulation of CBR in the HIV-1 Tat Transgenic Mouse Model of Hand. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 31372820 DOI: 10.1007/s11481-019-09867-w  0.96
2019 Schurman LD, Carper MC, Moncayo LV, Ogasawara D, Richardson K, Yu L, Liu X, Poklis JL, Liu QS, Cravatt BF, Lichtman AH. Diacylglycerol lipase-alpha regulates hippocampal-dependent learning and memory processes in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31127001 DOI: 10.1523/JNEUROSCI.1353-18.2019  0.96
2019 Tseng CC, Baillie G, Donvito G, Mustafa M, Juola S, Zanato C, Massarenti C, Dall'Angelo S, Harrison WTA, Lichtman AH, Ross R, Zanda M, Greig IR. The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators (PAMs). Journal of Medicinal Chemistry. PMID 31050898 DOI: 10.1021/acs.jmedchem.9b00252  0.72
2019 Petrie GN, Wills KL, Piscitelli F, Smoum R, Limebeer CL, Rock EM, Humphrey AE, Sheppard-Perkins M, Lichtman AH, Mechoulam R, Di Marzo V, Parker LA. Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats. Psychopharmacology. PMID 30993360 DOI: 10.1007/s00213-019-05237-9  0.72
2018 Donvito G, Muldoon PP, Jackson KJ, Ahmad U, Zaveri NT, McIntosh JM, Chen X, Lichtman AH, Damaj MI. Neuronal nicotinic acetylcholine receptors mediate ∆ -THC dependence: Mouse and human studies. Addiction Biology. PMID 30378732 DOI: 10.1111/adb.12691  0.76
2018 Hermes DJ, Xu C, Poklis JL, Niphakis MJ, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. Neuropharmacology. PMID 30114402 DOI: 10.1016/j.neuropharm.2018.08.013  0.96
2018 Sim-Selley LJ, Wilkerson JL, Burston JJ, Hauser KF, McLane V, Welch SP, Lichtman AH, Selley DE. Differential Tolerance to FTY720-induced Antinociception in Acute Thermal and Nerve Injury Mouse Pain Models: Role of S1P Receptor Adaptation. The Journal of Pharmacology and Experimental Therapeutics. PMID 29945931 DOI: 10.1124/jpet.118.248260  0.8
2018 Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, ... Lichtman AH, et al. N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology. PMID 29567093 DOI: 10.1016/j.neuropharm.2018.03.020  0.76
2018 Curry Z, Wilkerson J, Bagdas D, Kyte S, Patel N, Donvito G, Mustafa MA, Poklis J, Niphakis M, Hsu KL, Cravatt BF, Gewirtz DA, Damaj MI, Lichtman AH. Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced neuropathy. The Journal of Pharmacology and Experimental Therapeutics. PMID 29540562 DOI: 10.1124/jpet.117.245704  0.96
2018 Wilkerson JL, Curry ZA, Kinlow PD, Mason BL, Hsu KL, van der Stelt M, Cravatt BF, Lichtman AH. Evaluation of different drug classes on transient sciatic nerve injury-depressed marble burying in mice. Pain. PMID 29528965 DOI: 10.1097/j.pain.0000000000001199  0.96
2017 Kyte SL, Toma W, Bagdas D, Meade JA, Schurman LD, Lichtman AH, Chen ZJ, Del Fabbro E, Fang X, Bigbee JW, Damaj MI, Gewirtz DA. Nicotine prevents and reverses paclitaxel-induced mechanical allodynia in a mouse model of CIPN. The Journal of Pharmacology and Experimental Therapeutics. PMID 29042416 DOI: 10.1124/jpet.117.243972  0.76
2017 Wilkerson JL, Donvito G, Grim TW, Abdullah RA, Ogasawara D, Cravatt BF, Lichtman AH. Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model. The Journal of Pharmacology and Experimental Therapeutics. PMID 28970359 DOI: 10.1124/jpet.117.243808  0.96
2017 Shin M, Snyder HW, Donvito G, Schurman LD, Fox TE, Lichtman AH, Kester M, Hsu KL. Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo. Molecular Pharmaceutics. PMID 28901776 DOI: 10.1021/acs.molpharmaceut.7b00657  0.84
2017 Donvito G, Nass SR, Wilkerson JL, Curry ZA, Schurman LD, Kinsey SG, Lichtman AH. The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28857069 DOI: 10.1038/npp.2017.204  1
2017 Xu C, Hermes DJ, Nwanguma B, Jacobs IR, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska B, Fitting S. Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. Molecular and Cellular Neurosciences. PMID 28733129 DOI: 10.1016/j.mcn.2017.07.003  0.72
2017 Owens RA, Mustafa MA, Ignatowska-Jankowska BM, Damaj MI, Beardsley PM, Wiley JL, Niphakis MJ, Cravatt BF, Lichtman AH. Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice. Neuropharmacology. PMID 28673548 DOI: 10.1016/j.neuropharm.2017.06.032  0.96
2017 Donvito G, Bagdas D, Toma W, Rahimpour E, Jackson A, Meade JA, AlSharari S, Kulkarni AR, Ivy Carroll F, Lichtman AH, Papke RL, Thakur GA, Imad Damaj M. The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice. Experimental Neurology. PMID 28606623 DOI: 10.1016/j.expneurol.2017.06.014  0.68
2017 Schurman LD, Smith TL, Morales AJ, Lee NN, Reeves TM, Phillips LL, Lichtman AH. Investigation of left and right lateral fluid percussion injury in C57BL6/J mice: In vivo functional consequences. Neuroscience Letters. PMID 28527714 DOI: 10.1016/j.neulet.2017.05.032  0.76
2017 Grim TW, Morales AJ, Thomas BF, Wiley JL, Endres GW, Negus SS, Lichtman AH. Apparent CB1 receptor rimonabant affinity estimates: combination with THC and synthetic cannabinoids in the mouse in vivo triad model. The Journal of Pharmacology and Experimental Therapeutics. PMID 28442584 DOI: 10.1124/jpet.117.240192  0.96
2017 Jackson A, Bagdas D, Muldoon PP, Lichtman AH, Carroll FI, Greenwald M, Miles MF, Damaj MI. In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence. Neuropharmacology. PMID 28279662 DOI: 10.1016/j.neuropharm.2017.03.005  0.76
2017 Schurman LD, Lichtman AH. Endocannabinoids: A Promising Impact for Traumatic Brain Injury. Frontiers in Pharmacology. 8: 69. PMID 28261100 DOI: 10.3389/fphar.2017.00069  0.76
2017 Toma W, Kyte SL, Bagdas D, Alkhlaif Y, Alsharari SD, Lichtman AH, Chen ZJ, Del Fabbro E, Bigbee JW, Gewirtz DA, Damaj MI. Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse. Neuropharmacology. PMID 28237807 DOI: 10.1016/j.neuropharm.2017.02.020  0.76
2017 Soethoudt M, Grether U, Fingerle J, Grim TW, Fezza F, de Petrocellis L, Ullmer C, Rothenhäusler B, Perret C, van Gils N, Finlay D, MacDonald C, Chicca A, Gens MD, Stuart J, ... ... Lichtman AH, et al. Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. Nature Communications. 8: 13958. PMID 28045021 DOI: 10.1038/ncomms13958  0.84
2016 Wilkerson JL, Ghosh S, Mustafa M, Abdullah RA, Niphakis MJ, Cabrera R, Maldonado RL, Cravatt BF, Lichtman AH. The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice. Neuropharmacology. PMID 27890602 DOI: 10.1016/j.neuropharm.2016.11.015  0.96
2016 Donvito G, Wilkerson JL, Damaj MI, Lichtman AH. Palmitoylethanolamide reverses paclitaxel-induced allodynia in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 27608657 DOI: 10.1124/jpet.116.236182  0.76
2016 Grim TW, Morales AJ, Gonek MM, Wiley JL, Thomas BF, Endres GW, Sim-Selley LJ, Selley DE, Negus SS, Lichtman AH. Stratification of cannabinoid 1 receptor (CB1R) agonist efficacy: Manipulation of CB1R density through use of transgenic mice reveals congruence between in vivo and in vitro assays. The Journal of Pharmacology and Experimental Therapeutics. PMID 27535976 DOI: 10.1124/jpet.116.233163  0.96
2016 Wiley JL, Lefever TW, Pulley NS, Marusich JA, Cravatt BF, Lichtman AH. Just add water: cannabinoid discrimination in a water T-maze with FAAH(-/-) and FAAH(+/+) mice. Behavioural Pharmacology. 27: 479-484. PMID 27385208 DOI: 10.1097/FBP.0000000000000228  0.92
2016 Wiley JL, Owens RA, Lichtman AH. Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids. Current Topics in Behavioral Neurosciences. PMID 27278640 DOI: 10.1007/7854_2016_24  0.96
2016 Bagdas D, Wilkerson JL, Kulkarni A, Toma W, AlSharari S, Gul Z, Lichtman AH, Papke RL, Thakur GA, Imad Damaj M. The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain. British Journal of Pharmacology. PMID 27243753 DOI: 10.1111/bph.13528  0.92
2016 Grim TW, Samano KL, Ignatowska-Jankowska B, Tao Q, Sim-Selly LJ, Selley DE, Wise LE, Poklis A, Lichtman AH. Pharmacological characterization of repeated administration of the first generation abused synthetic cannabinoid CP47,497. Journal of Basic and Clinical Physiology and Pharmacology. 27: 217-28. PMID 27149200 DOI: 10.1515/jbcpp-2015-0118  1
2016 Xu C, Hermes DJ, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 26993829 DOI: 10.1007/s11481-016-9664-y  0.92
2016 Wilkerson JL, Ghosh S, Bagdas D, Mason BL, Crowe MS, Hsu KL, Wise LE, Kinsey SG, Damaj MI, Cravatt BF, Lichtman AH. Diacylglycerol lipase beta inhibition reverses nociceptive behavior in mouse models of inflammatory and neuropathic pain. British Journal of Pharmacology. PMID 26915789 DOI: 10.1111/bph.13469  0.92
2016 Hahn YK, Paris JJ, Lichtman AH, Hauser KF, Sim-Selley LJ, Selley DE, Knapp PE. Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and β-arrestin 2 activity in the forebrain. Neurobiology of Disease. PMID 26845176 DOI: 10.1016/j.nbd.2016.01.014  0.92
2016 Wilkerson JL, Niphakis MJ, Grim TW, Mustafa MA, Abdullah RA, Poklis JL, Dewey WL, Akbarali HI, Banks ML, Wise LE, Cravatt BF, Lichtman AH. The selective monoacylglycerol lipase inhibitor MJN110 produces opioid sparing effects in a mouse neuropathic pain model. The Journal of Pharmacology and Experimental Therapeutics. PMID 26791602 DOI: 10.1124/jpet.115.229971  1
2015 Sticht MA, Limebeer CL, Rafla BR, Abdullah RA, Poklis JL, Ho W, Niphakis MJ, Cravatt BF, Sharkey KA, Lichtman AH, Parker LA. Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortex. Neuropharmacology. PMID 26541329 DOI: 10.1016/j.neuropharm.2015.10.039  0.92
2015 Viader A, Blankman JL, Zhong P, Liu X, Schlosburg JE, Joslyn CM, Liu QS, Tomarchio AJ, Lichtman AH, Selley DE, Sim-Selley LJ, Cravatt BF. Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action. Cell Reports. PMID 26212325 DOI: 10.1016/j.celrep.2015.06.075  1
2015 Lazenka MF, Tomarchio A, Lichtman AH, Greengard P, Flajolet M, Selley DE, Sim-Selley LJ. Role of dopamine type 1 receptors and DARPP-32 in Δ9-THC-mediated induction of ΔFosB in the mouse forebrain. The Journal of Pharmacology and Experimental Therapeutics. PMID 26099530 DOI: 10.1124/jpet.115.224428  0.92
2015 Cabral GA, Rogers TJ, Lichtman AH. Turning Over a New Leaf: Cannabinoid and Endocannabinoid Modulation of Immune Function. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 10: 193-203. PMID 26054900 DOI: 10.1007/s11481-015-9615-z  1
2015 Ignatowska-Jankowska BM, Baillie GL, Kinsey S, Crowe M, Ghosh S, Allen Owens R, Imad Damaj M, Poklis J, Wiley JL, Zanda M, Zanato C, Greig IR, Lichtman AH, Ross RA. A Cannabinoid CB1 Receptor Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with no Psychoactive Effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26052038 DOI: 10.1038/npp.2015.148  0.92
2015 Ghosh S, Kinsey SG, Liu QS, Hruba L, McMahon LR, Grim TW, Merritt CR, Wise LE, Abdullah RA, Selley DE, Sim-Selley LJ, Cravatt BF, Lichtman AH. Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice. The Journal of Pharmacology and Experimental Therapeutics. 354: 111-20. PMID 25998048 DOI: 10.1124/jpet.115.222851  1
2015 Grim TW, Wiebelhaus JM, Morales AJ, Negus SS, Lichtman AH. Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice. Drug and Alcohol Dependence. 150: 31-7. PMID 25772438 DOI: 10.1016/j.drugalcdep.2015.01.022  1
2015 Ignatowska-Jankowska B, Wilkerson JL, Mustafa M, Abdullah R, Niphakis M, Wiley JL, Cravatt BF, Lichtman AH. Selective monoacylglycerol lipase inhibitors: antinociceptive versus cannabimimetic effects in mice. The Journal of Pharmacology and Experimental Therapeutics. 353: 424-32. PMID 25762694 DOI: 10.1124/jpet.114.222315  0.92
2015 Poklis JL, Clay DJ, Ignatowska-Jankowska BM, Zanato C, Ross RA, Greig IR, Abdullah RA, Mustafa MA, Lichtman AH, Poklis A. HPLC-MS-MS Determination of ZCZ-011, A Novel Pharmacological Tool for Investigation of the Cannabinoid Receptor in Mouse Brain Using Clean Screen FASt™ Column Extraction. Journal of Analytical Toxicology. 39: 353-8. PMID 25737338 DOI: 10.1093/jat/bkv015  0.84
2015 Nass SR, Long JZ, Schlosburg JE, Cravatt BF, Lichtman AH, Kinsey SG. Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 10: 364-70. PMID 25715681 DOI: 10.1007/s11481-015-9593-1  1
2015 Hruba L, Seillier A, Zaki A, Cravatt BF, Lichtman AH, Giuffrida A, McMahon LR. Simultaneous inhibition of fatty acid amide hydrolase and monoacylglycerol lipase shares discriminative stimulus effects with Δ9-tetrahydrocannabinol in mice. The Journal of Pharmacology and Experimental Therapeutics. 353: 261-8. PMID 25711338 DOI: 10.1124/jpet.115.222836  0.96
2015 Gamage TF, Ignatowska-Jankowska BM, Muldoon PP, Cravatt BF, Damaj MI, Lichtman AH. Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice. Drug and Alcohol Dependence. 146: 7-16. PMID 25479915 DOI: 10.1016/j.drugalcdep.2014.11.015  1
2015 Wiebelhaus JM, Grim TW, Owens RA, Lazenka MF, Sim-Selley LJ, Abdullah RA, Niphakis MJ, Vann RE, Cravatt BF, Wiley JL, Negus SS, Lichtman AH. Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice. The Journal of Pharmacology and Experimental Therapeutics. 352: 195-207. PMID 25398241 DOI: 10.1124/jpet.114.218677  1
2015 Muldoon PP, Chen J, Harenza JL, Abdullah RA, Sim-Selley LJ, Cravatt BF, Miles MF, Chen X, Lichtman AH, Damaj MI. Inhibition of monoacylglycerol lipase reduces nicotine withdrawal. British Journal of Pharmacology. 172: 869-82. PMID 25258021 DOI: 10.1111/bph.12948  1
2015 Parker LA, Niphakis MJ, Downey R, Limebeer CL, Rock EM, Sticht MA, Morris H, Abdullah RA, Lichtman AH, Cravatt BF. Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus. Psychopharmacology. 232: 583-93. PMID 25085768 DOI: 10.1007/s00213-014-3696-x  1
2014 Brown JD, Lin CY, Duan Q, Griffin G, Federation AJ, Paranal RM, Bair S, Newton G, Lichtman AH, Kung AL, Yang T, Wang H, Luscinskas FW, Croce KJ, Bradner JE, et al. NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis. Molecular Cell. 56: 219-31. PMID 25263595 DOI: 10.1016/j.molcel.2014.08.024  0.72
2014 Sexton M, Cudaback E, Abdullah RA, Finnell J, Mischley LK, Rozga M, Lichtman AH, Stella N. Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters. Inflammopharmacology. 22: 295-303. PMID 25135301 DOI: 10.1007/s10787-014-0214-z  1
2014 Lazenka MF, David BG, Lichtman AH, Nestler EJ, Selley DE, Sim-Selley LJ. Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions. Biochemical Pharmacology. 91: 380-9. PMID 25093286 DOI: 10.1016/j.bcp.2014.07.024  1
2014 Grim TW, Ghosh S, Hsu KL, Cravatt BF, Kinsey SG, Lichtman AH. Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models. Pharmacology, Biochemistry, and Behavior. 124: 405-11. PMID 25058512 DOI: 10.1016/j.pbb.2014.07.008  1
2014 Hait NC, Wise LE, Allegood JC, O'Brien M, Avni D, Reeves TM, Knapp PE, Lu J, Luo C, Miles MF, Milstien S, Lichtman AH, Spiegel S. Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. Nature Neuroscience. 17: 971-80. PMID 24859201 DOI: 10.1038/nn.3728  1
2014 Wiley JL, Walentiny DM, Wright MJ, Beardsley PM, Burston JJ, Poklis JL, Lichtman AH, Vann RE. Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. European Journal of Pharmacology. 737: 97-105. PMID 24858366 DOI: 10.1016/j.ejphar.2014.05.013  1
2014 Schlosburg JE, Kinsey SG, Ignatowska-Jankowska B, Ramesh D, Abdullah RA, Tao Q, Booker L, Long JZ, Selley DE, Cravatt BF, Lichtman AH. Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 350: 196-204. PMID 24849924 DOI: 10.1124/jpet.114.212753  1
2014 Samano KL, Poklis JL, Lichtman AH, Poklis A. Development of a high-performance liquid chromatography-tandem mass spectrometry method for the identification and quantification of CP-47,497, CP-47,497-C8 and JWH-250 in mouse brain. Journal of Analytical Toxicology. 38: 307-14. PMID 24816398 DOI: 10.1093/jat/bku043  0.72
2014 Gamage TF, Ignatowska-Jankowska BM, Wiley JL, Abdelrahman M, Trembleau L, Greig IR, Thakur GA, Tichkule R, Poklis J, Ross RA, Pertwee RG, Lichtman AH. In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. Behavioural Pharmacology. 25: 182-5. PMID 24603340 DOI: 10.1097/FBP.0000000000000027  1
2014 Kwilasz AJ, Abdullah RA, Poklis JL, Lichtman AH, Negus SS. Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats. Behavioural Pharmacology. 25: 119-29. PMID 24583930 DOI: 10.1097/FBP.0000000000000023  1
2014 Emery SM, Alotaibi MR, Tao Q, Selley DE, Lichtman AH, Gewirtz DA. Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 348: 293-302. PMID 24259678 DOI: 10.1124/jpet.113.205120  1
2014 Limebeer CL, Abdullah RA, Rock EM, Imhof E, Wang K, Lichtman AH, Parker LA. Attenuation of anticipatory nausea in a rat model of contextually elicited conditioned gaping by enhancement of the endocannabinoid system. Psychopharmacology. 231: 603-12. PMID 24043345 DOI: 10.1007/s00213-013-3282-7  1
2014 Ignatowska-Jankowska BM, Ghosh S, Crowe MS, Kinsey SG, Niphakis MJ, Abdullah RA, Tao Q, O' Neal ST, Walentiny DM, Wiley JL, Cravatt BF, Lichtman AH. In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects. British Journal of Pharmacology. 171: 1392-407. PMID 23848221 DOI: 10.1111/bph.12298  1
2013 Burston JJ, Sagar DR, Shao P, Bai M, King E, Brailsford L, Turner JM, Hathway GJ, Bennett AJ, Walsh DA, Kendall DA, Lichtman A, Chapman V. Cannabinoid CB2 receptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint. Plos One. 8: e80440. PMID 24282543 DOI: 10.1371/journal.pone.0080440  1
2013 Ignatowska-Jankowska BM, Muldoon PP, Lichtman AH, Damaj MI. The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice. Psychopharmacology. 229: 591-601. PMID 23652588 DOI: 10.1007/s00213-013-3117-6  1
2013 Otrubova K, Brown M, McCormick MS, Han GW, O'Neal ST, Cravatt BF, Stevens RC, Lichtman AH, Boger DL. Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues. Journal of the American Chemical Society. 135: 6289-99. PMID 23581831 DOI: 10.1021/ja4014997  1
2013 Kinsey SG, Wise LE, Ramesh D, Abdullah R, Selley DE, Cravatt BF, Lichtman AH. Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects. The Journal of Pharmacology and Experimental Therapeutics. 345: 492-501. PMID 23412396 DOI: 10.1124/jpet.112.201426  1
2013 Ramesh D, Gamage TF, Vanuytsel T, Owens RA, Abdullah RA, Niphakis MJ, Shea-Donohue T, Cravatt BF, Lichtman AH. Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1039-49. PMID 23303065 DOI: 10.1038/npp.2012.269  1
2013 Fitting S, Ignatowska-Jankowska BM, Bull C, Skoff RP, Lichtman AH, Wise LE, Fox MA, Su J, Medina AE, Krahe TE, Knapp PE, Guido W, Hauser KF. Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 Tat transgenic mice. Biological Psychiatry. 73: 443-53. PMID 23218253 DOI: 10.1016/j.biopsych.2012.09.026  1
2013 AlSharari SD, Akbarali HI, Abdullah RA, Shahab O, Auttachoat W, Ferreira GA, White KL, Lichtman AH, Cabral GA, Damaj MI. Novel insights on the effect of nicotine in a murine colitis model. The Journal of Pharmacology and Experimental Therapeutics. 344: 207-17. PMID 23115221 DOI: 10.1124/jpet.112.198796  1
2013 Freitas K, Ghosh S, Ivy Carroll F, Lichtman AH, Imad Damaj M. Effects of α7 positive allosteric modulators in murine inflammatory and chronic neuropathic pain models. Neuropharmacology. 65: 156-64. PMID 23079470 DOI: 10.1016/j.neuropharm.2012.08.022  1
2013 Bisogno T, Mahadevan A, Coccurello R, Chang JW, Allarà M, Chen Y, Giacovazzo G, Lichtman A, Cravatt B, Moles A, Di Marzo V. A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects British Journal of Pharmacology. 169: 784-793. PMID 23072382 DOI: 10.1111/bph.12013  1
2013 Ghosh S, Wise LE, Chen Y, Gujjar R, Mahadevan A, Cravatt BF, Lichtman AH. The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model. Life Sciences. 92: 498-505. PMID 22749865 DOI: 10.1016/j.lfs.2012.06.020  1
2013 Muldoon PP, Lichtman AH, Parsons LH, Damaj MI. The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. Life Sciences. 92: 458-62. PMID 22705310 DOI: 10.1016/j.lfs.2012.05.015  1
2013 Fowler CJ, Björklund E, Lichtman AH, Naidu PS, Congiu C, Onnis V. Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide. Journal of Enzyme Inhibition and Medicinal Chemistry. 28: 172-82. PMID 22225576 DOI: 10.3109/14756366.2011.643304  1
2013 Gillespie NA, Lichtman A, Kendler KS. The Genetics of Cannabis Use and Cannabis Use Disorders Biological Research On Addiction. 523-531. DOI: 10.1016/B978-0-12-398335-0.00051-0  1
2012 Schlosburg JE, Radanova L, Di Marzo V, Imming P, Lichtman AH. Evaluation of the endogenous cannabinoid system in mediating the behavioral effects of dipyrone (metamizol) in mice. Behavioural Pharmacology. 23: 722-6. PMID 22954646 DOI: 10.1097/FBP.0b013e3283584794  1
2012 Wise LE, Premaratne ID, Gamage TF, Lichtman AH, Hughes LD, Harris LS, Aceto MD. l-theanine attenuates abstinence signs in morphine-dependent rhesus monkeys and elicits anxiolytic-like activity in mice. Pharmacology, Biochemistry, and Behavior. 103: 245-52. PMID 22935630 DOI: 10.1016/j.pbb.2012.08.008  1
2012 Wise LE, Long KA, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH. Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice. Acs Chemical Neuroscience. 3: 369-78. PMID 22860205 DOI: 10.1021/cn200130s  1
2012 Wiebelhaus JM, Poklis JL, Poklis A, Vann RE, Lichtman AH, Wise LE. Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice. Drug and Alcohol Dependence. 126: 316-23. PMID 22776442 DOI: 10.1016/j.drugalcdep.2012.05.034  1
2012 Ross GR, Lichtman A, Dewey WL, Akbarali HI. Evidence for the putative cannabinoid receptor (GPR55)-mediated inhibitory effects on intestinal contractility in mice. Pharmacology. 90: 55-65. PMID 22759743 DOI: 10.1159/000339076  1
2012 Ritter JK, Li C, Xia M, Poklis JL, Lichtman AH, Abdullah RA, Dewey WL, Li PL. Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. The Journal of Pharmacology and Experimental Therapeutics. 342: 770-9. PMID 22685343 DOI: 10.1124/jpet.112.196451  1
2012 Poklis JL, Amira D, Wise LE, Wiebelhaus JM, Haggerty BJ, Lichtman AH, Poklis A. Determination of naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in mouse blood and tissue after inhalation exposure to 'buzz' smoke by HPLC/MS/MS. Biomedical Chromatography : Bmc. 26: 1393-8. PMID 22407432 DOI: 10.1002/bmc.2710  1
2012 Gatta L, Piscitelli F, Giordano C, Boccella S, Lichtman A, Maione S, Di Marzo V. Discovery of prostamide F 2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability Plos One. 7. PMID 22363560 DOI: 10.1371/journal.pone.0031111  1
2012 Oleson EB, Beckert MV, Morra JT, Lansink CS, Cachope R, Abdullah RA, Loriaux AL, Schetters D, Pattij T, Roitman MF, Lichtman AH, Cheer JF. Endocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum. Neuron. 73: 360-73. PMID 22284189 DOI: 10.1016/j.neuron.2011.11.018  0.72
2012 Rogosch T, Sinning C, Podlewski A, Watzer B, Schlosburg J, Lichtman AH, Cascio MG, Bisogno T, Di Marzo V, Nüsing R, Imming P. Novel bioactive metabolites of dipyrone (metamizol). Bioorganic & Medicinal Chemistry. 20: 101-7. PMID 22172309 DOI: 10.1016/j.bmc.2011.11.028  1
2012 Gamage TF, Lichtman AH. The endocannabinoid system: role in energy regulation. Pediatric Blood & Cancer. 58: 144-8. PMID 22076835 DOI: 10.1002/pbc.23367  1
2012 Booker L, Kinsey SG, Abdullah RA, Blankman JL, Long JZ, Ezzili C, Boger DL, Cravatt BF, Lichtman AH. The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. British Journal of Pharmacology. 165: 2485-96. PMID 21506952 DOI: 10.1111/j.1476-5381.2011.01445.x  1
2012 Bátkai S, Mukhopadhyay P, Horváth B, Rajesh M, Gao RY, Mahadevan A, Amere M, Battista N, Lichtman AH, Gauson LA, Maccarrone M, Pertwee RG, Pacher P. Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors. British Journal of Pharmacology. 165: 2450-61. PMID 21470208 DOI: 10.1111/j.1476-5381.2011.01410.x  1
2011 Ramesh D, Schlosburg JE, Wiebelhaus JM, Lichtman AH. Marijuana dependence: not just smoke and mirrors. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 52: 295-308. PMID 23382144 DOI: 10.1093/ilar.52.3.295  1
2011 Nomura DK, Morrison BE, Blankman JL, Long JZ, Kinsey SG, Marcondes MC, Ward AM, Hahn YK, Lichtman AH, Conti B, Cravatt BF. Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation. Science (New York, N.Y.). 334: 809-13. PMID 22021672 DOI: 10.1126/science.1209200  1
2011 DeLong GT, Wolf CE, Poklis A, Lichtman A. Cannabichromene and tetrahydrocannabinol determination in mouse blood and brain by gas chromatography-mass spectrometry. Journal of Analytical Toxicology. 35: 496-500. PMID 21871159  0.72
2011 Kinsey SG, Naidu PS, Cravatt BF, Dudley DT, Lichtman AH. Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice. Pharmacology, Biochemistry, and Behavior. 99: 718-25. PMID 21740924 DOI: 10.1016/j.pbb.2011.06.022  1
2011 Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH. Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice. The Journal of Pharmacology and Experimental Therapeutics. 339: 173-85. PMID 21719468 DOI: 10.1124/jpet.111.181370  1
2011 Kinsey SG, Nomura DK, O'Neal ST, Long JZ, Mahadevan A, Cravatt BF, Grider JR, Lichtman AH. Inhibition of monoacylglycerol lipase attenuates nonsteroidal anti-inflammatory drug-induced gastric hemorrhages in mice. The Journal of Pharmacology and Experimental Therapeutics. 338: 795-802. PMID 21659471 DOI: 10.1124/jpet.110.175778  1
2011 Wise LE, Varvel SA, Selley DE, Wiebelhaus JM, Long KA, Middleton LS, Sim-Selley LJ, Lichtman AH. delta(9)-Tetrahydrocannabinol-dependent mice undergoing withdrawal display impaired spatial memory. Psychopharmacology. 217: 485-94. PMID 21559804 DOI: 10.1007/s00213-011-2305-5  1
2011 Ezzili C, Mileni M, McGlinchey N, Long JZ, Kinsey SG, Hochstatter DG, Stevens RC, Lichtman AH, Cravatt BF, Bilsky EJ, Boger DL. Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics. Journal of Medicinal Chemistry. 54: 2805-22. PMID 21428410 DOI: 10.1021/jm101597x  1
2011 Bu DX, Griffin G, Lichtman AH. Mechanisms for the anti-inflammatory effects of statins. Current Opinion in Lipidology. 22: 165-70. PMID 21412153 DOI: 10.1097/MOL.0b013e3283453e41  0.72
2011 Lichtman AH, Chapman V. A FAAH-fetched approach to treat osteoarthritis pain. Pain. 152: 959-60. PMID 21371823 DOI: 10.1016/j.pain.2011.02.034  1
2011 Schlosburg JE, O'Neal ST, Conrad DH, Lichtman AH. CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action. Psychopharmacology. 216: 323-31. PMID 21340468 DOI: 10.1007/s00213-011-2224-5  1
2011 Soderstrom K, Poklis JL, Lichtman AH. Cannabinoid exposure during zebra finch sensorimotor vocal learning persistently alters expression of endocannabinoid signaling elements and acute agonist responsiveness. Bmc Neuroscience. 12: 3. PMID 21211022 DOI: 10.1186/1471-2202-12-3  1
2011 Kinsey SG, O'Neal ST, Long JZ, Cravatt BF, Lichtman AH. Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay. Pharmacology, Biochemistry, and Behavior. 98: 21-7. PMID 21145341 DOI: 10.1016/j.pbb.2010.12.002  1
2011 Avraham Y, Saidian M, Burston JJ, Mevorach R, Vorobiev L, Magen I, Kunkes E, Borges B, Lichtman AH, Berry EM. Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. The Journal of Nutritional Biochemistry. 22: 766-76. PMID 21109417 DOI: 10.1016/j.jnutbio.2010.07.001  1
2011 Kinsey SG, Mahadevan A, Zhao B, Sun H, Naidu PS, Razdan RK, Selley DE, Imad Damaj M, Lichtman AH. The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects. Neuropharmacology. 60: 244-51. PMID 20849866 DOI: 10.1016/j.neuropharm.2010.09.004  1
2010 Poklis JL, Thompson CC, Long KA, Lichtman AH, Poklis A. Disposition of cannabichromene, cannabidiol, and Δ⁹-tetrahydrocannabinol and its metabolites in mouse brain following marijuana inhalation determined by high-performance liquid chromatography-tandem mass spectrometry. Journal of Analytical Toxicology. 34: 516-20. PMID 21258613  0.76
2010 Lichtman AH, Blankman JL, Cravatt BF. Endocannabinoid overload. Molecular Pharmacology. 78: 993-5. PMID 20952498 DOI: 10.1124/mol.110.069427  1
2010 Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, et al. Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. Nature Neuroscience. 13: 1113-9. PMID 20729846 DOI: 10.1038/nn.2616  1
2010 DeLong GT, Wolf CE, Poklis A, Lichtman AH. Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol. Drug and Alcohol Dependence. 112: 126-33. PMID 20619971 DOI: 10.1016/j.drugalcdep.2010.05.019  0.72
2010 Kinsey SG, Long JZ, Cravatt BF, Lichtman AH. Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms. The Journal of Pain : Official Journal of the American Pain Society. 11: 1420-8. PMID 20554481 DOI: 10.1016/j.jpain.2010.04.001  1
2010 Naidu PS, Kinsey SG, Guo TL, Cravatt BF, Lichtman AH. Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase. The Journal of Pharmacology and Experimental Therapeutics. 334: 182-90. PMID 20375198 DOI: 10.1124/jpet.109.164806  1
2010 Falenski KW, Thorpe AJ, Schlosburg JE, Cravatt BF, Abdullah RA, Smith TH, Selley DE, Lichtman AH, Sim-Selley LJ. FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1775-87. PMID 20357755 DOI: 10.1038/npp.2010.44  1
2009 Varvel SA, Wise LE, Lichtman AH. Are CB(1) Receptor Antagonists Nootropic or Cognitive Impairing Agents? Drug Development Research. 70: 555-565. PMID 20539824 DOI: 10.1002/ddr.20334  1
2009 Long JZ, Nomura DK, Vann RE, Walentiny DM, Booker L, Jin X, Burston JJ, Sim-Selley LJ, Lichtman AH, Wiley JL, Cravatt BF. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 20270-5. PMID 19918051 DOI: 10.1073/pnas.0909411106  1
2009 Booker L, Naidu PS, Razdan RK, Mahadevan A, Lichtman AH. Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception. Drug and Alcohol Dependence. 105: 42-7. PMID 19679411 DOI: 10.1016/j.drugalcdep.2009.06.009  1
2009 Wise LE, Harloe JP, Lichtman AH. Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. Neurobiology of Learning and Memory. 92: 597-601. PMID 19524055 DOI: 10.1016/j.nlm.2009.06.001  1
2009 Kinsey SG, Long JZ, O'Neal ST, Abdullah RA, Poklis JL, Boger DL, Cravatt BF, Lichtman AH. Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 330: 902-10. PMID 19502530 DOI: 10.1124/jpet.109.155465  1
2009 Schlosburg JE, Carlson BL, Ramesh D, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH. Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice. The Aaps Journal. 11: 342-52. PMID 19430909 DOI: 10.1208/s12248-009-9110-7  1
2009 Wise LE, Thorpe AJ, Lichtman AH. Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2072-80. PMID 19322169 DOI: 10.1038/npp.2009.31  1
2009 Schlosburg JE, Kinsey SG, Lichtman AH. Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. The Aaps Journal. 11: 39-44. PMID 19184452 DOI: 10.1208/s12248-008-9075-y  1
2009 Schlosburg JE, Boger DL, Cravatt BF, Lichtman AH. Endocannabinoid modulation of scratching response in an acute allergenic model: a new prospective neural therapeutic target for pruritus. The Journal of Pharmacology and Experimental Therapeutics. 329: 314-23. PMID 19168707 DOI: 10.1124/jpet.108.150136  1
2009 Naidu PS, Booker L, Cravatt BF, Lichtman AH. Synergy between enzyme inhibitors of fatty acid amide hydrolase and cyclooxygenase in visceral nociception. The Journal of Pharmacology and Experimental Therapeutics. 329: 48-56. PMID 19118134 DOI: 10.1124/jpet.108.143487  1
2009 Long JZ, Li W, Booker L, Burston JJ, Kinsey SG, Schlosburg JE, Pavón FJ, Serrano AM, Selley DE, Parsons LH, Lichtman AH, Cravatt BF. Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nature Chemical Biology. 5: 37-44. PMID 19029917 DOI: 10.1038/nchembio.129  1
2009 Fowler CJ, Naidu PS, Lichtman A, Onnis V. The case for the development of novel analgesic agents targeting both fatty acid amide hydrolase and either cyclooxygenase or TRPV1 British Journal of Pharmacology. 156: 412-419. DOI: 10.1111/j.1476-5381.2008.00029.x  1
2008 Harloe JP, Thorpe AJ, Lichtman AH. Differential endocannabinoid regulation of extinction in appetitive and aversive Barnes maze tasks. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 806-9. PMID 18957525 DOI: 10.1101/lm.1113008  1
2008 Nomura DK, Hudak CS, Ward AM, Burston JJ, Issa RS, Fisher KJ, Abood ME, Wiley JL, Lichtman AH, Casida JE. Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. Bioorganic & Medicinal Chemistry Letters. 18: 5875-8. PMID 18752948 DOI: 10.1016/j.bmcl.2008.08.007  1
2008 Wise LE, Iredale PA, Lichtman AH. The cannabinoid CB(1) receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task. European Journal of Pharmacology. 590: 246-9. PMID 18602386 DOI: 10.1016/j.ejphar.2008.06.049  1
2008 Merritt LL, Martin BR, Walters C, Lichtman AH, Damaj MI. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of Pharmacology and Experimental Therapeutics. 326: 483-92. PMID 18451315 DOI: 10.1124/jpet.108.138321  1
2008 Oltmanns MH, Samudre SS, Castillo IG, Hosseini A, Lichtman AH, Allen RC, Lattanzio FA, Williams PB. Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 24: 104-15. PMID 18201139 DOI: 10.1089/jop.2007.0074  1
2008 Wise LE, Cannavacciulo R, Cravatt BF, Martin BF, Lichtman AH. Evaluation of fatty acid amides in the carrageenan-induced paw edema model. Neuropharmacology. 54: 181-8. PMID 17675189 DOI: 10.1016/j.neuropharm.2007.06.003  1
2007 Wise LE, Lichtman AH. The uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist memantine prolongs spatial memory in a rat delayed radial-arm maze memory task. European Journal of Pharmacology. 575: 98-102. PMID 17850786 DOI: 10.1016/j.ejphar.2007.07.059  1
2007 Niyuhire F, Varvel SA, Martin BR, Lichtman AH. Exposure to marijuana smoke impairs memory retrieval in mice. The Journal of Pharmacology and Experimental Therapeutics. 322: 1067-75. PMID 17586723 DOI: 10.1124/jpet.107.119594  1
2007 Varvel SA, Martin BR, Lichtman AH. Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine. Psychopharmacology. 193: 511-9. PMID 17497137 DOI: 10.1007/s00213-007-0811-2  1
2007 Naidu PS, Lichtman AH, Archer CC, May EL, Harris LS, Aceto MD. NIH 11082 produces anti-depressant-like activity in the mouse tail-suspension test through a delta-opioid receptor mechanism of action. European Journal of Pharmacology. 566: 132-6. PMID 17459369 DOI: 10.1016/j.ejphar.2007.03.031  1
2007 Naidu PS, Varvel SA, Ahn K, Cravatt BF, Martin BR, Lichtman AH. Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. Psychopharmacology. 192: 61-70. PMID 17279376 DOI: 10.1007/s00213-006-0689-4  1
2007 Pertwee RG, Thomas A, Stevenson LA, Ross RA, Varvel SA, Lichtman AH, Martin BR, Razdan RK. The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo. British Journal of Pharmacology. 150: 586-94. PMID 17245367 DOI: 10.1038/sj.bjp.0707124  1
2007 Wise LE, Shelton CC, Cravatt BF, Martin BR, Lichtman AH. Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. European Journal of Pharmacology. 557: 44-8. PMID 17217945 DOI: 10.1016/j.ejphar.2006.11.002  1
2007 Wise LE, Iredale PA, Stokes RJ, Lichtman AH. Combination of rimonabant and donepezil prolongs spatial memory duration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1805-12. PMID 17213845 DOI: 10.1038/sj.npp.1301297  1
2007 Niyuhire F, Varvel SA, Thorpe AJ, Stokes RJ, Wiley JL, Lichtman AH. The disruptive effects of the CB1 receptor antagonist rimonabant on extinction learning in mice are task-specific. Psychopharmacology. 191: 223-31. PMID 17211653 DOI: 10.1007/s00213-006-0650-6  1
2007 Hoffman AF, Oz M, Yang R, Lichtman AH, Lupica CR. Opposing actions of chronic Delta9-tetrahydrocannabinol and cannabinoid antagonists on hippocampal long-term potentiation. Learning & Memory (Cold Spring Harbor, N.Y.). 14: 63-74. PMID 17202425 DOI: 10.1101/lm.439007  1
2007 Varvel SA, Wise LE, Niyuhire F, Cravatt BF, Lichtman AH. Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1032-41. PMID 17047668 DOI: 10.1038/sj.npp.1301224  1
2006 Wilson DM, Varvel SA, Harloe JP, Martin BR, Lichtman AH. SR 141716 (Rimonabant) precipitates withdrawal in marijuana-dependent mice. Pharmacology, Biochemistry, and Behavior. 85: 105-13. PMID 16934319 DOI: 10.1016/j.pbb.2006.07.018  1
2006 Varvel SA, Wiley JL, Yang R, Bridgen DT, Long K, Lichtman AH, Martin BR. Interactions between THC and cannabidiol in mouse models of cannabinoid activity. Psychopharmacology. 186: 226-34. PMID 16572263 DOI: 10.1007/s00213-006-0356-9  1
2006 Varvel SA, Cravatt BF, Engram AE, Lichtman AH. Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. The Journal of Pharmacology and Experimental Therapeutics. 317: 251-7. PMID 16352706 DOI: 10.1124/jpet.105.095059  1
2006 Lichtman AH, Martin BR. Understanding the pharmacology and physiology of cannabis dependence Cannabis Dependence: Its Nature, Consequences, and Treatment. 37-57. DOI: 10.1017/CBO9780511544248.005  1
2005 Lichtman AH, Martin BR. Cannabinoid tolerance and dependence. Handbook of Experimental Pharmacology. 691-717. PMID 16596793 DOI: 10.1007/3-540-26573-2-24  1
2005 Lichtman AH, Cravatt BF. Food for thought: endocannabinoid modulation of lipogenesis. The Journal of Clinical Investigation. 115: 1130-3. PMID 15864340 DOI: 10.1172/JCI25076  1
2005 Varvel SA, Bridgen DT, Tao Q, Thomas BF, Martin BR, Lichtman AH. Delta9-tetrahydrocannbinol accounts for the antinociceptive, hypothermic, and cataleptic effects of marijuana in mice. The Journal of Pharmacology and Experimental Therapeutics. 314: 329-37. PMID 15831444 DOI: 10.1124/jpet.104.080739  1
2005 Varvel SA, Anum EA, Lichtman AH. Disruption of CB(1) receptor signaling impairs extinction of spatial memory in mice. Psychopharmacology. 179: 863-72. PMID 15619104 DOI: 10.1007/s00213-004-2121-2  1
2005 Varvel SA, Anum E, Niyuhire F, Wise LE, Lichtman AH. Delta(9)-THC-induced cognitive deficits in mice are reversed by the GABA(A) antagonist bicuculline. Psychopharmacology. 178: 317-27. PMID 15322725 DOI: 10.1007/s00213-004-1988-2  1
2004 Cravatt BF, Lichtman AH. The endogenous cannabinoid system and its role in nociceptive behavior. Journal of Neurobiology. 61: 149-60. PMID 15362158 DOI: 10.1002/neu.20080  1
2004 Cravatt BF, Saghatelian A, Hawkins EG, Clement AB, Bracey MH, Lichtman AH. Functional disassociation of the central and peripheral fatty acid amide signaling systems. Proceedings of the National Academy of Sciences of the United States of America. 101: 10821-6. PMID 15247426 DOI: 10.1073/pnas.0401292101  1
2004 Lichtman AH, Leung D, Shelton CC, Saghatelian A, Hardouin C, Boger DL, Cravatt BF. Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity. The Journal of Pharmacology and Experimental Therapeutics. 311: 441-8. PMID 15229230 DOI: 10.1124/jpet.104.069401  1
2004 Lichtman AH, Shelton CC, Advani T, Cravatt BF. Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. Pain. 109: 319-27. PMID 15157693 DOI: 10.1016/j.pain.2004.01.022  1
2003 Mechoulam R, Lichtman AH. Neuroscience. Stout guards of the central nervous system. Science (New York, N.Y.). 302: 65-7. PMID 14526067 DOI: 10.1126/science.1091256  1
2003 Cravatt BF, Lichtman AH. Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. Current Opinion in Chemical Biology. 7: 469-75. PMID 12941421 DOI: 10.1016/S1367-5931(03)00079-6  1
2003 Clement AB, Hawkins EG, Lichtman AH, Cravatt BF. Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3916-23. PMID 12736361  1
2002 Cravatt BF, Lichtman AH. The enzymatic inactivation of the fatty acid amide class of signaling lipids. Chemistry and Physics of Lipids. 121: 135-48. PMID 12505696 DOI: 10.1016/S0009-3084(02)00147-0  1
2002 Lichtman AH, Martin BR. Marijuana withdrawal syndrome in the animal model. Journal of Clinical Pharmacology. 42: 20S-27S. PMID 12412832  1
2002 Wilson DM, Peart J, Martin BR, Bridgen DT, Byron PR, Lichtman AH. Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler. Drug and Alcohol Dependence. 67: 259-67. PMID 12127197 DOI: 10.1016/S0376-8716(02)00078-9  1
2002 Lichtman AH, Hawkins EG, Griffin G, Cravatt BF. Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. The Journal of Pharmacology and Experimental Therapeutics. 302: 73-9. PMID 12065702 DOI: 10.1124/jpet.302.1.73  1
2002 Lichtman AH, Varvel SA, Martin BR. Endocannabinoids in cognition and dependence. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 66: 269-85. PMID 12052042 DOI: 10.1054/plef.2001.0351  1
2002 Varvel SA, Lichtman AH. Evaluation of CB1 receptor knockout mice in the Morris water maze. The Journal of Pharmacology and Experimental Therapeutics. 301: 915-24. PMID 12023519 DOI: 10.1124/jpet.301.3.915  1
2001 O'Neal CL, Poklis A, Lichtman AH. Acetylcodeine, an impurity of illicitly manufactured heroin, elicits convulsions, antinociception, and locomotor stimulation in mice. Drug and Alcohol Dependence. 65: 37-43. PMID 11714588 DOI: 10.1016/S0376-8716(01)00145-4  1
2001 Varvel SA, Hamm RJ, Martin BR, Lichtman AH. Differential effects of delta 9-THC on spatial reference and working memory in mice. Psychopharmacology. 157: 142-50. PMID 11594438 DOI: 10.1007/s002130100780  1
2001 Lichtman AH, Sheikh SM, Loh HH, Martin BR. Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice. The Journal of Pharmacology and Experimental Therapeutics. 298: 1007-14. PMID 11504797  1
2001 Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Giang DK, Martin BR, Lichtman AH. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proceedings of the National Academy of Sciences of the United States of America. 98: 9371-6. PMID 11470906 DOI: 10.1073/pnas.161191698  1
2001 Lichtman AH, Fisher J, Martin BR. Precipitated cannabinoid withdrawal is reversed by Delta(9)-tetrahydrocannabinol or clonidine. Pharmacology, Biochemistry, and Behavior. 69: 181-8. PMID 11420084 DOI: 10.1016/S0091-3057(01)00514-7  1
2001 Lichtman AH, Poklis JL, Poklis A, Wilson DM, Martin BR. The pharmacological activity of inhalation exposure to marijuana smoke in mice. Drug and Alcohol Dependence. 63: 107-16. PMID 11376914 DOI: 10.1016/S0376-8716(00)00205-2  1
2000 Lichtman AH. SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats. European Journal of Pharmacology. 404: 175-9. PMID 10980277 DOI: 10.1016/S0014-2999(00)00615-4  1
2000 Lichtman AH, Peart J, Poklis JL, Bridgen DT, Razdan RK, Wilson DM, Poklis A, Meng Y, Byron PR, Martin BR. Pharmacological evaluation of aerosolized cannabinoids in mice. European Journal of Pharmacology. 399: 141-9. PMID 10884513 DOI: 10.1016/S0014-2999(00)00321-6  1
1999 Meng Y, Dukat M, Bridgen DT, Martin BR, Lichtman AH. Pharmacological effects of methamphetamine and other stimulants via inhalation exposure. Drug and Alcohol Dependence. 53: 111-20. PMID 10080037 DOI: 10.1016/S0376-8716(98)00120-3  1
1998 Martin BR, Lichtman AH. Cannabinoid transmission and pain perception. Neurobiology of Disease. 5: 447-61. PMID 9974177 DOI: 10.1006/nbdi.1998.0218  1
1998 Lichtman AH, Wiley JL, LaVecchia KL, Neviaser ST, Arthur DB, Wilson DM, Martin BR. Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. European Journal of Pharmacology. 357: 139-48. PMID 9797029 DOI: 10.1016/S0014-2999(98)00558-5  1
1997 Meng Y, Lichtman AH, Bridgen DT, Martin BR. Inhalation studies with drugs of abuse. Nida Research Monograph. 173: 201-24. PMID 9260190  1
1997 Lichtman AH, Martin BR. The selective cannabinoid antagonist SR 141716A blocks cannabinoid-induced antinociception in rats. Pharmacology, Biochemistry, and Behavior. 57: 7-12. PMID 9164547  1
1996 Wiley JL, Compton DR, Gordon PM, Siegel C, Singer M, Dutta A, Lichtman AH, Balster RL, Razdan RK, Martin BR. Evaluation of agonist-antagonist properties of nitrogen mustard and cyano derivatives of delta 8-tetrahydrocannabinol. Neuropharmacology. 35: 1793-804. PMID 9076759 DOI: 10.1016/S0028-3908(96)00120-7  1
1996 Meng Y, Lichtman AH, Bridgen DT, Martin BR. Pharmacological potency and biodisposition of phencyclidine via inhalation exposure in mice. Drug and Alcohol Dependence. 43: 13-22. PMID 8957139 DOI: 10.1016/S0376-8716(96)01284-7  1
1996 Lichtman AH, Meng Y, Martin BR. Inhalation exposure to volatilized opioids produces antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 279: 69-76. PMID 8858977  1
1996 Lichtman AH, Martin BR. Delta 9-tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism. Psychopharmacology. 126: 125-31. PMID 8856831  1
1996 Lichtman AH, Cook SA, Martin BR. Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement. The Journal of Pharmacology and Experimental Therapeutics. 276: 585-93. PMID 8632325  1
1995 Moore KA, Lichtman AH, Poklis A, Borzelleca JF. alpha-Benzyl-N-methylphenethylamine (BNMPA), an impurity of illicit methamphetamine synthesis: pharmacological evaluation and interaction with methamphetamine. Drug and Alcohol Dependence. 39: 83-9. PMID 8529536  0.72
1995 Cook SA, Welch SP, Lichtman AH, Martin BR. Evaluation of cAMP involvement in cannabinoid-induced antinociception. Life Sciences. 56: 2049-56. PMID 7776831  1
1995 Lichtman AH, Dimen KR, Martin BR. Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats. Psychopharmacology. 119: 282-90. PMID 7675962  1
1995 Lichtman AH, Sathe P, Dimen KR, Martin BR. Acute tolerance to the cardiovascular effects of volatilized cocaine free base in rats. Drug and Alcohol Dependence. 38: 247-54. PMID 7555625  1
1993 Lichtman AH, Smith FL, Martin BR. Evidence that the antinociceptive tail-flick response is produced independently from changes in either tail-skin temperature or core temperature. Pain. 55: 283-95. PMID 8121689  1
1992 Lichtman AH, Smith PB, Martin BR. The antinociceptive effects of intrathecally administered cannabinoids are influenced by lipophilicity. Pain. 51: 19-26. PMID 1454400  1
1991 Lichtman AH, Fanselow MS. Opioid and nonopioid conditional analgesia: the role of spinal opioid, noradrenergic, and serotonergic systems. Behavioral Neuroscience. 105: 687-98. PMID 1667731 DOI: 10.1037/0735-7044.105.5.687  1
1991 Lichtman AH, Martin BR. Cannabinoid-induced antinociception is mediated by a spinal alpha 2-noradrenergic mechanism. Brain Research. 559: 309-14. PMID 1665384 DOI: 10.1016/0006-8993(91)90017-P  1
1991 Lichtman AH, Martin BR. Spinal and supraspinal components of cannabinoid-induced antinociception. The Journal of Pharmacology and Experimental Therapeutics. 258: 517-23. PMID 1650831  1
1990 Borszcz GS, Lichtman AH, Hughes HC. Comparison of escape and tail flick thresholds in the rat: a psychophysical analysis of morphine hypoalgesia. Physiology & Behavior. 47: 1017-22. PMID 2388930 DOI: 10.1016/0031-9384(90)90028-3  1
1990 McLaughlin CR, Lichtman AH, Fanselow MS, Cramer CP. Tonic nociception in neonatal rats. Pharmacology, Biochemistry, and Behavior. 36: 859-62. PMID 2217514 DOI: 10.1016/0091-3057(90)90090-5  1
1990 Lichtman AH, Fanselow MS. Cats produce analgesia in rats on the tail-flick test: naltrexone sensitivity is determined by the nociceptive test stimulus. Brain Research. 533: 91-4. PMID 2085738 DOI: 10.1016/0006-8993(90)91800-V  1
1990 Bateman ST, Lichtman AH, Cramer CP. Peripheral serotonergic inhibition of suckling. Pharmacology, Biochemistry, and Behavior. 37: 219-25. PMID 2080185 DOI: 10.1016/0091-3057(90)90324-B  1
1990 Lichtman AH, Martin BR. Spinal action of cannabinoid-induced antinociception. Nida Research Monograph. 105: 422-4. PMID 1876060  1
1989 Lichtman AH, Cramer CP. Relative importance of experience, social facilitation, and availability of milk in weaning of rats. Developmental Psychobiology. 22: 347-56. PMID 2721817 DOI: 10.1002/dev.420220403  1
1989 Lichtman AH, Cramer CP. Methysergide-induced nipple attachment depends on suckling experience in juvenile rats. Behavioral Neuroscience. 103: 254-61. PMID 2706072 DOI: 10.1037/0735-7044.103.2.254  1
1989 McLaughlin CR, Lichtman AH, Fanselow MS, Cramer CP. Pro-Leu-Gly-NH2 serves as a conditioned stimulus in the acquisition of conditioned tolerance. Behavioral Neuroscience. 103: 447-51. PMID 2565116 DOI: 10.1037/0735-7044.103.2.447  1
1989 McLaughlin CR, Lichtman AH, Pretlow JP, Cramer CP. The ontogenesis of lithium-induced effects on suckling: inhibition and facilitation. Developmental Psychobiology. 22: 803-15. PMID 2517630 DOI: 10.1002/dev.420220805  1
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