Yun Guan - Publications

Affiliations: 
National Institute of Dental and Craniofacial Research 
Area:
pain

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Liu S, Huang Q, He S, Chen Z, Gao X, Ma D, Duan W, Ford N, Yang F, Chen X, Raja SN, Hao D, Guan Y. Dermorphin [D-Arg2, Lys4] (1-4) amide inhibits below-level heat hypersensitivity in mice after contusive thoracic spinal cord injury. Pain. PMID 31365470 DOI: 10.1097/j.pain.0000000000001671  0.36
2019 Duan W, Huang Q, Chen Z, Raja SN, Yang F, Guan Y. Comparisons of motor and sensory abnormalities after lumbar and thoracic contusion spinal cord injury in male rats. Neuroscience Letters. 134358. PMID 31269465 DOI: 10.1016/j.neulet.2019.134358  0.36
2019 Raja SN, Sivanesan E, Guan Y. Central Sensitization, N-methyl-D-aspartate Receptors, and Human Experimental Pain Models: Bridging the Gap between Target Discovery and Drug Development. Anesthesiology. PMID 31233408 DOI: 10.1097/ALN.0000000000002808  0.36
2019 Yang F, Duan W, Huang Q, Chen Z, Ford N, Gao X, Sivanesan E, Sarma SV, Vera-Portocarrero LP, Linderoth B, Raja SN, Guan Y. Modulation of Spinal Nociceptive Transmission by Sub-Sensory Threshold Spinal Cord Stimulation in Rats After Nerve Injury. Neuromodulation : Journal of the International Neuromodulation Society. PMID 31162783 DOI: 10.1111/ner.12975  0.36
2018 Sivanesan E, Maher DP, Raja SN, Linderoth B, Guan Y. Supraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain: Five Decades of Research and Prospects for the Future. Anesthesiology. PMID 30556812 DOI: 10.1097/ALN.0000000000002353  0.36
2018 Chen Z, Huang Q, Yang F, Shi C, Sivanesan E, Liu S, Chen X, Sarma SV, Vera-Portocarrero LP, Linderoth B, Raja SN, Guan Y. The Impact of Electrical Charge Delivery on Inhibition of Mechanical Hypersensitivity in Nerve-Injured Rats by Sub-Sensory Threshold Spinal Cord Stimulation. Neuromodulation : Journal of the International Neuromodulation Society. PMID 30556616 DOI: 10.1111/ner.12910  0.36
2018 He SQ, Xu Q, Tiwari V, Yang F, Anderson M, Chen Z, Grenald SA, Raja SN, Dong X, Guan Y. Oligomerization of MrgC11 and μ-opioid receptors in sensory neurons enhances morphine analgesia. Science Signaling. 11. PMID 29921657 DOI: 10.1126/scisignal.aao3134  0.36
2018 Yang F, Anderson M, He S, Stephens K, Zheng Y, Chen Z, Raja SN, Aplin F, Guan Y, Fridman G. Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current. Science Advances. 4: eaaq1438. PMID 29651458 DOI: 10.1126/sciadv.aaq1438  0.36
2018 Tiwari V, Anderson M, Yang F, Tiwari V, Zheng Q, He SQ, Zhang T, Shu B, Chen X, Grenald SA, Stephens KE, Chen Z, Dong X, Raja SN, Guan Y. Peripherally Acting μ-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats. Anesthesiology. PMID 29601322 DOI: 10.1097/ALN.0000000000002191  0.36
2018 Sdrulla AD, Guan Y, Raja SN. Spinal Cord Stimulation: Clinical Efficacy and Potential Mechanisms. Pain Practice : the Official Journal of World Institute of Pain. PMID 29526043 DOI: 10.1111/papr.12692  0.36
2017 Li Z, Tseng PY, Tiwari V, Xu Q, He SQ, Wang Y, Zheng Q, Han L, Wu Z, Blobaum AL, Cui Y, Tiwari V, Sun S, Cheng Y, Huang-Lionnet JH, ... ... Guan Y, et al. Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223516 DOI: 10.1073/pnas.1615255114  0.36
2016 Yang F, Xu Q, Shu B, Tiwari V, He SQ, Vera-Portocarrero LP, Dong X, Linderoth B, Raja SN, Wang Y, Guan Y. Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation. Pain. PMID 27589093 DOI: 10.1097/j.pain.0000000000000680  0.36
2016 Chao YC, Xie F, Li X, Guo R, Yang N, Zhang C, Shi R, Guan Y, Yue Y, Wang Y. Demethylation regulation of BDNF gene expression in dorsal root ganglion neurons is implicated in opioid-induced pain hypersensitivity in rats. Neurochemistry International. PMID 26970395 DOI: 10.1016/j.neuint.2016.03.007  1
2016 Tiwari V, Tiwari V, He S, Zhang T, Raja SN, Dong X, Guan Y. Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy. Advances in Experimental Medicine and Biology. 904: 87-103. PMID 26900065 DOI: 10.1007/978-94-017-7537-3_7  0.36
2015 Wang C, Wang Z, Yang Y, Zhu C, Wu G, Yu G, Jian T, Yang N, Shi H, Tang M, He Q, Lan L, Liu Q, Guan Y, Dong X, et al. Pirt contributes to uterine contraction-induced pain in mice. Molecular Pain. 11: 57. PMID 26376721 DOI: 10.1186/s12990-015-0054-x  1
2015 Yang F, Zhang T, Tiwari V, Shu B, Zhang C, Wang Y, Vera-Portocarrero LP, Raja SN, Guan Y. Effects of Combined Electrical Stimulation of the Dorsal Column and Dorsal Roots on Wide-Dynamic-Range Neuronal Activity in Nerve-Injured Rats. Neuromodulation : Journal of the International Neuromodulation Society. PMID 26307526 DOI: 10.1111/ner.12341  1
2015 Xie F, Li X, Bao M, Guo R, Zhang C, Wu A, Yue Y, Guan Y, Wang Y. Plerixafor may treat intractable post-herpetic neuralgia. Medical Hypotheses. PMID 26175195 DOI: 10.1016/j.mehy.2015.07.005  1
2015 Wang Y, Zhang M, Xie F, Li X, Bao M, Yang N, Shi R, Wang Z, Wu A, Guan Y, Yue Y. Upregulation of α2δ-1 Calcium Channel Subunit in the Spinal Cord Contributes to Pelvic Organ Cross-Sensitization in a Rat Model of Experimentally-Induced Endometriosis. Neurochemical Research. 40: 1267-73. PMID 25935199 DOI: 10.1007/s11064-015-1592-3  1
2015 Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 85: 833-46. PMID 25640077 DOI: 10.1016/j.neuron.2014.12.065  1
2015 Yang F, Zhang C, Xu Q, Tiwari V, He SQ, Wang Y, Dong X, Vera-Portocarrero LP, Wacnik PW, Raja SN, Guan Y. Electrical stimulation of dorsal root entry zone attenuates wide-dynamic-range neuronal activity in rats. Neuromodulation : Journal of the International Neuromodulation Society. 18: 33-40; discussion 40. PMID 25308522 DOI: 10.1111/ner.12249  1
2014 Guo R, Zhao Y, Zhang M, Wang Y, Shi R, Liu Y, Xu J, Wu A, Yue Y, Wu J, Guan Y, Wang Y. Down-regulation of Stargazin inhibits the enhanced surface delivery of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor GluR1 subunit in rat dorsal horn and ameliorates postoperative pain. Anesthesiology. 121: 609-19. PMID 25093662 DOI: 10.1097/ALN.0000000000000291  1
2014 Tiwari V, Guan Y, Raja SN. Modulating the delicate glial-neuronal interactions in neuropathic pain: promises and potential caveats. Neuroscience and Biobehavioral Reviews. 45: 19-27. PMID 24820245 DOI: 10.1016/j.neubiorev.2014.05.002  1
2014 Li Z, He SQ, Xu Q, Yang F, Tiwari V, Liu Q, Tang Z, Han L, Chu YX, Wang Y, Hin N, Tsukamoto T, Slusher B, Guan X, Wei F, ... Guan Y, et al. Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice. Pain. 155: 1613-21. PMID 24813294 DOI: 10.1016/j.pain.2014.05.008  1
2014 Xu Q, Cheong YK, He SQ, Tiwari V, Liu J, Wang Y, Raja SN, Li J, Guan Y, Li W. Suppression of spinal connexin 43 expression attenuates mechanical hypersensitivity in rats after an L5 spinal nerve injury. Neuroscience Letters. 566: 194-9. PMID 24631560 DOI: 10.1016/j.neulet.2014.03.004  1
2014 Xu Q, Cheong YK, Yang F, Tiwari V, Li J, Liu J, Raja SN, Li W, Guan Y. Intrathecal carbenoxolone inhibits neuropathic pain and spinal wide-dynamic range neuronal activity in rats after an L5 spinal nerve injury. Neuroscience Letters. 563: 45-50. PMID 24486838 DOI: 10.1016/j.neulet.2014.01.042  1
2014 He SQ, Li Z, Chu YX, Han L, Xu Q, Li M, Yang F, Liu Q, Tang Z, Wang Y, Hin N, Tsukamoto T, Slusher B, Tiwari V, Shechter R, ... Guan Y, et al. MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain. Pain. 155: 534-44. PMID 24333779 DOI: 10.1016/j.pain.2013.12.008  1
2013 Shechter R, Yang F, Xu Q, Cheong YK, He SQ, Sdrulla A, Carteret AF, Wacnik PW, Dong X, Meyer RA, Raja SN, Guan Y. Conventional and kilohertz-frequency spinal cord stimulation produces intensity- and frequency-dependent inhibition of mechanical hypersensitivity in a rat model of neuropathic pain. Anesthesiology. 119: 422-32. PMID 23880991 DOI: 10.1097/ALN.0b013e31829bd9e2  1
2013 He SQ, Yang F, Perez FM, Xu Q, Shechter R, Cheong YK, Carteret AF, Dong X, Sweitzer SM, Raja SN, Guan Y. Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats. Pain. 154: 2477-86. PMID 23880055 DOI: 10.1016/j.pain.2013.07.023  1
2013 Xu Q, Li WY, Guan Y. Mu-opioidergic modulation differs in deep and superficial wide-dynamic range dorsal horn neurons in mice. Neuroscience Letters. 549: 157-62. PMID 23748039 DOI: 10.1016/j.neulet.2013.05.059  1
2013 Han L, Ma C, Liu Q, Weng HJ, Cui Y, Tang Z, Kim Y, Nie H, Qu L, Patel KN, Li Z, McNeil B, He S, Guan Y, Xiao B, et al. A subpopulation of nociceptors specifically linked to itch. Nature Neuroscience. 16: 174-82. PMID 23263443 DOI: 10.1038/nn.3289  1
2012 Ringkamp M, Tal M, Hartke TV, Wooten M, McKelvy A, Turnquist BP, Guan Y, Meyer RA, Raja SN. Local loperamide injection reduces mechanosensitivity of rat cutaneous, nociceptive C-fibers. Plos One. 7: e42105. PMID 22848720 DOI: 10.1371/journal.pone.0042105  1
2012 Xiong W, Cui T, Cheng K, Yang F, Chen SR, Willenbring D, Guan Y, Pan HL, Ren K, Xu Y, Zhang L. Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. The Journal of Experimental Medicine. 209: 1121-34. PMID 22585736 DOI: 10.1084/jem.20120242  1
2012 Guan Y. Spinal cord stimulation: neurophysiological and neurochemical mechanisms of action. Current Pain and Headache Reports. 16: 217-25. PMID 22399391 DOI: 10.1007/s11916-012-0260-4  1
2011 Yang F, Chung CY, Wacnik PW, Carteret AF, McKelvy AD, Meyer RA, Raja SN, Guan Y. Electrical stimulation at distinct peripheral sites in spinal nerve injured rats leads to different afferent activation profiles. Neuroscience Letters. 505: 52-7. PMID 22001268 DOI: 10.1016/j.neulet.2011.09.065  1
2011 Park U, Vastani N, Guan Y, Raja SN, Koltzenburg M, Caterina MJ. TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11425-36. PMID 21832173 DOI: 10.1523/JNEUROSCI.1384-09.2011  1
2011 Donello JE, Guan Y, Tian M, Cheevers CV, Alcantara M, Cabrera S, Raja SN, Gil DW. A peripheral adrenoceptor-mediated sympathetic mechanism can transform stress-induced analgesia into hyperalgesia. Anesthesiology. 114: 1403-16. PMID 21540738 DOI: 10.1097/ALN.0b013e31821c3878  1
2011 Lee CY, Perez FM, Wang W, Guan X, Zhao X, Fisher JL, Guan Y, Sweitzer SM, Raja SN, Tao YX. Dynamic temporal and spatial regulation of mu opioid receptor expression in primary afferent neurons following spinal nerve injury. European Journal of Pain (London, England). 15: 669-75. PMID 21310637 DOI: 10.1016/j.ejpain.2010.11.018  1
2010 Guan Y, Wacnik PW, Yang F, Carteret AF, Chung CY, Meyer RA, Raja SN. Spinal cord stimulation-induced analgesia: electrical stimulation of dorsal column and dorsal roots attenuates dorsal horn neuronal excitability in neuropathic rats. Anesthesiology. 113: 1392-405. PMID 21068658 DOI: 10.1097/ALN.0b013e3181fcd95c  1
2010 Guan X, Wang L, Chen CL, Guan Y, Li S. Roles of two subtypes of corticotrophin-releasing factor receptor in the corticostriatal long-term potentiation under cocaine withdrawal condition. Journal of Neurochemistry. 115: 795-803. PMID 20807310 DOI: 10.1111/j.1471-4159.2010.06981.x  1
2010 Guan Y, Liu Q, Tang Z, Raja SN, Anderson DJ, Dong X. Mas-related G-protein-coupled receptors inhibit pathological pain in mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 15933-8. PMID 20724664 DOI: 10.1073/pnas.1011221107  1
2010 Guan Y, Raja SN. Wide-dynamic-range neurons are heterogeneous in windup responsiveness to changes in stimulus intensity and isoflurane anesthesia level in mice. Journal of Neuroscience Research. 88: 2272-83. PMID 20209628 DOI: 10.1002/jnr.22383  1
2010 Guan Y, Yuan F, Carteret AF, Raja SN. A partial L5 spinal nerve ligation induces a limited prolongation of mechanical allodynia in rats: an efficient model for studying mechanisms of neuropathic pain. Neuroscience Letters. 471: 43-7. PMID 20067820 DOI: 10.1016/j.neulet.2010.01.006  1
2009 Liu Q, Tang Z, Surdenikova L, Kim S, Patel KN, Kim A, Ru F, Guan Y, Weng HJ, Geng Y, Undem BJ, Kollarik M, Chen ZF, Anderson DJ, Dong X. Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus. Cell. 139: 1353-65. PMID 20004959 DOI: 10.1016/j.cell.2009.11.034  1
2009 Seal RP, Wang X, Guan Y, Raja SN, Woodbury CJ, Basbaum AI, Edwards RH. Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors. Nature. 462: 651-5. PMID 19915548 DOI: 10.1038/nature08505  1
2009 Singh OV, Yaster M, Xu JT, Guan Y, Guan X, Dharmarajan AM, Raja SN, Zeitlin PL, Tao YX. Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury. Proteomics. 9: 1241-53. PMID 19206110 DOI: 10.1002/pmic.200800636  1
2008 Park JS, Yaster M, Guan X, Xu JT, Shih MH, Guan Y, Raja SN, Tao YX. Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory pain. Molecular Pain. 4: 67. PMID 19116032 DOI: 10.1186/1744-8069-4-67  1
2008 Guan Y, Johanek LM, Hartke TV, Shim B, Tao YX, Ringkamp M, Meyer RA, Raja SN. Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury. Pain. 138: 318-29. PMID 18276075 DOI: 10.1016/j.pain.2008.01.004  1
2007 Guan Y, Yaster M, Raja SN, Tao YX. Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice. Molecular Pain. 3: 29. PMID 17922909 DOI: 10.1186/1744-8069-3-29  1
2006 Guan Y, Borzan J, Meyer RA, Raja SN. Windup in dorsal horn neurons is modulated by endogenous spinal mu-opioid mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4298-307. PMID 16624950 DOI: 10.1523/JNEUROSCI.0960-06.2006  1
2005 Chu YC, Guan Y, Skinner J, Raja SN, Johns RA, Tao YX. Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain. Pain. 119: 113-23. PMID 16297560 DOI: 10.1016/j.pain.2005.09.024  1
2005 Shimizu I, Iida T, Guan Y, Zhao C, Raja SN, Jarvis MF, Cockayne DA, Caterina MJ. Enhanced thermal avoidance in mice lacking the ATP receptor P2X3. Pain. 116: 96-108. PMID 15927378 DOI: 10.1016/j.pain.2005.03.030  1
2004 Guan Y, Guo W, Robbins MT, Dubner R, Ren K. Changes in AMPA receptor phosphorylation in the rostral ventromedial medulla after inflammatory hyperalgesia in rats. Neuroscience Letters. 366: 201-5. PMID 15276247 DOI: 10.1016/j.neulet.2004.05.051  1
2003 Guan Y, Guo W, Zou SP, Dubner R, Ren K. Inflammation-induced upregulation of AMPA receptor subunit expression in brain stem pain modulatory circuitry. Pain. 104: 401-13. PMID 12855351 DOI: 10.1016/S0304-3959(03)00048-4  1
2002 Guo W, Zou S, Guan Y, Ikeda T, Tal M, Dubner R, Ren K. Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6208-17. PMID 12122079  1
2002 Guan Y, Terayama R, Dubner R, Ren K. Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammation. The Journal of Pharmacology and Experimental Therapeutics. 300: 513-20. PMID 11805211 DOI: 10.1124/jpet.300.2.513  1
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