Xinzhong Dong - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Liu Y, Liu Y, Limjunyawong N, Narang C, Jamaldeen H, Yu S, Patiram S, Nie H, Caterina MJ, Dong X, Qu L. Sensory neuron expressed TRPC3 mediates acute and chronic itch. Pain. PMID 35507377 DOI: 10.1097/j.pain.0000000000002668  0.328
2022 Kim H, Kim H, Cho H, Lee B, Lu HJ, Kim K, Chung S, Shim WS, Shin YK, Dong X, Wood JN, Oh U. Anoctamin 1/TMEM16A in pruritoceptors is essential for Mas-related G protein receptor-dependent itch. Pain. PMID 35135993 DOI: 10.1097/j.pain.0000000000002611  0.634
2022 Berhane I, Hin N, Thomas AG, Huang Q, Zhang C, Veeravalli V, Wu Y, Ng J, Alt J, Rojas C, Hihara H, Aoki M, Yoshizawa K, Nishioka T, Suzuki S, ... Dong X, et al. Thieno[2,3-]pyrimidine-Based Positive Allosteric Modulators of Human Mas-Related G Protein-Coupled Receptor X1 (MRGPRX1). Journal of Medicinal Chemistry. PMID 35119273 DOI: 10.1021/acs.jmedchem.1c01709  0.638
2022 Kothari R, Dong X. Scratching the surface of itch receptors. Trends in Pharmacological Sciences. 43: 168-170. PMID 35039148 DOI: 10.1016/j.tips.2021.12.005  0.503
2021 Chen Z, Huang Q, Song X, Ford NC, Zhang C, Xu Q, Lay M, He SQ, Dong X, Hanani M, Guan Y. Purinergic signaling between neurons and satellite glial cells of mouse dorsal root ganglia modulates neuronal excitability in vivo. Pain. PMID 35027518 DOI: 10.1097/j.pain.0000000000002556  0.618
2021 Ford NC, Barpujari A, He SQ, Huang Q, Zhang C, Dong X, Guan Y, Raja SN. Role of primary sensory neurone cannabinoid type-1 receptors in pain and the analgesic effects of the peripherally acting agonist CB-13 in mice. British Journal of Anaesthesia. PMID 34844727 DOI: 10.1016/j.bja.2021.10.020  0.644
2021 Zheng Q, Xie W, Lückemeyer DD, Lay M, Wang XW, Dong X, Limjunyawong N, Ye Y, Zhou FQ, Strong JA, Zhang JM, Dong X. Synchronized cluster firing, a distinct form of sensory neuron activation, drives spontaneous pain. Neuron. PMID 34752775 DOI: 10.1016/j.neuron.2021.10.019  0.599
2021 Xu Q, Ford NC, He S, Huang Q, Anderson M, Chen Z, Yang F, Crawford LK, Caterina MJ, Guan Y, Dong X. Astrocytes contribute to pain gating in the spinal cord. Science Advances. 7: eabi6287. PMID 34730998 DOI: 10.1126/sciadv.abi6287  0.541
2021 Sutaria N, Alphonse MP, Marani M, Parthasarathy V, Deng J, Wongvibulsin S, Williams K, Roh YS, Choi J, Bordeaux Z, Pritchard T, Dillen C, Semenov YR, Kwatra MM, Archer NK, ... Dong X, et al. Cluster analysis of circulating plasma biomarkers in prurigo nodularis reveals a distinct systemic inflammatory signature in African Americans. The Journal of Investigative Dermatology. PMID 34717952 DOI: 10.1016/j.jid.2021.10.011  0.466
2021 Lawrence GW, Zurawski TH, Dong X, Dolly JO. Population Coding of Capsaicin Concentration by Sensory Neurons Revealed Using Ca Imaging of Dorsal Root Ganglia Explants from Adult pirt-GCaMP3 Mouse. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 55: 428-448. PMID 34242501 DOI: 10.33594/000000394  0.65
2021 Wongvibulsin S, Sutaria N, Kannan S, Alphonse MP, Belzberg M, Williams KA, Brown ID, Choi J, Roh YS, Pritchard T, Khanna R, Eseonu AC, Jedrych J, Dillen C, Kwatra MM, ... Dong X, et al. Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation. Scientific Reports. 11: 11175. PMID 34045476 DOI: 10.1038/s41598-021-90105-w  0.481
2021 Zaufel A, van de Wiel SMW, Yin L, Fauler G, Chien D, Dong X, Gilmer JF, Truong JK, Dawson P, van de Graaf SFJ, Fickert P, Moustafa T. Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 166153. PMID 33895309 DOI: 10.1016/j.bbadis.2021.166153  0.528
2021 Klein A, Solinski HJ, Malewicz NM, Ieong HF, Sypek EI, Shimada SG, Hartke TV, Wooten M, Wu G, Dong X, Hoon MA, LaMotte RH, Ringkamp M. Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates. Elife. 10. PMID 33891544 DOI: 10.7554/eLife.64506  0.607
2021 Belzberg M, Alphonse MP, Brown I, Williams KA, Khanna R, Ho B, Wongvibulsin S, Pritchard T, Roh YS, Sutaria N, Choi J, Jedrych J, Johnston AD, Sarkar K, Vasavda C, ... Dong X, et al. Prurigo Nodularis is Characterized by Systemic and Cutaneous Th22 Immune Polarization. The Journal of Investigative Dermatology. PMID 33771530 DOI: 10.1016/j.jid.2021.02.749  0.506
2021 Grundy L, Caldwell A, Garcia-Caraballo S, Grundy D, Spencer NJ, Dong X, Castro J, Harrington AM, Brierley SM. Activation of MrgprA3 and MrgprC11 on bladder-innervating afferents induces peripheral and central hypersensitivity to bladder distension. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33727332 DOI: 10.1523/JNEUROSCI.0033-21.2021  0.645
2021 Sun Q, Zhen G, Li TP, Guo Q, Li Y, Su W, Xue P, Wang X, Wan M, Guan Y, Dong X, Li S, Cai M, Cao X. Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice. Elife. 10. PMID 33646122 DOI: 10.7554/eLife.66532  0.561
2021 Wolf K, Kühn H, Boehm F, Gebhardt L, Glaudo M, Agelopoulos K, Ständer S, Ectors P, Zahn D, Riedel YK, Thimm D, Müller CE, Kretschmann S, Kremer AN, Chien D, ... Dong X, et al. A Group of Cationic Amphiphilic Drugs Activates MRGPRX2 and Induces Scratching Behavior in Mice. The Journal of Allergy and Clinical Immunology. PMID 33617860 DOI: 10.1016/j.jaci.2020.12.655  0.586
2021 Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR, Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X, ... Dong X, et al. A basophil-neuronal axis promotes itch. Cell. PMID 33450207 DOI: 10.1016/j.cell.2020.12.033  0.551
2020 Huang J, Lam H, Koziol-White C, Limjunyawong N, Kim D, Kim N, Karmacharya N, Rajkumar P, Firer D, Dalesio NM, Jude J, Kurten RC, Pluznick JL, Deshpande DA, Penn RB, ... Dong X, et al. The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Proceedings of the National Academy of Sciences of the United States of America. PMID 33097666 DOI: 10.1073/pnas.2003111117  0.543
2020 Meixiong J, Dong X, Weng HJ. Neuropathic Itch. Cells. 9. PMID 33050211 DOI: 10.3390/cells9102263  0.503
2020 Gao X, Han S, Huang Q, He S, Ford NC, Zheng Q, Chen Z, Yu S, Dong X, Guan Y. Calcium imaging in population of dorsal root ganglion neurons unravels novel mechanisms of visceral pain sensitization and referred somatic hypersensitivity. Pain. PMID 33021564 DOI: 10.1097/j.pain.0000000000002096  0.61
2020 Barpujari A, Ford N, He SQ, Huang Q, Gaveriaux-Ruff C, Dong X, Guan Y, Raja S. Role of peripheral sensory neuron mu-opioid receptors in nociceptive, inflammatory, and neuropathic pain. Regional Anesthesia and Pain Medicine. PMID 32928995 DOI: 10.1136/Rapm-2020-101779  0.633
2020 Patil MJ, Ru F, Sun H, Wang J, Kolbeck R, Dong X, Kollarik M, Canning BJ, Undem BJ. Acute activation of bronchopulmonary vagal nociceptors by type I interferons. The Journal of Physiology. PMID 32924209 DOI: 10.1113/Jp280276  0.638
2020 Shtessel M, Limjunyawong N, Oliver ET, Chichester K, Gao L, Dong X, Saini SS. MRGPRX2 Activation Causes Increased Skin Reactivity in Chronic Spontaneous Urticaria Patients. The Journal of Investigative Dermatology. PMID 32771471 DOI: 10.1016/J.Jid.2020.06.030  0.557
2020 Zhu J, Zhen G, An S, Wang X, Wan M, Li Y, Chen Z, Guan Y, Dong X, Hu Y, Cao X. Aberrant subchondral osteoblastic metabolism modifies NaV1.8 for osteoarthritis. Elife. 9. PMID 32441256 DOI: 10.7554/Elife.57656  0.641
2020 Lay M, Dong X. Neural Mechanisms of Itch. Annual Review of Neuroscience. PMID 32075517 DOI: 10.1146/Annurev-Neuro-083019-024537  0.644
2020 Meixiong J, Basso L, Dong X, Gaudenzio N. Nociceptor-Mast Cell Sensory Clusters as Regulators of Skin Homeostasis. Trends in Neurosciences. PMID 32014258 DOI: 10.1016/J.Tins.2020.01.001  0.552
2020 Ni S, Ling Z, Wang X, Cao Y, Wu T, Deng R, Crane JL, Skolasky R, Demehri S, Zhen G, Jain A, Wu P, Pan D, Hu B, Lyu X, ... ... Dong X, et al. Author Correction: Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice. Nature Communications. 11: 149. PMID 31907358 DOI: 10.1038/S41467-019-13970-0  0.588
2020 Zhu J, Zhen G, An S, Wang X, Wan M, Li Y, Chen Z, Guan Y, Dong X, Hu Y, Cao X. Author response: Aberrant subchondral osteoblastic metabolism modifies NaV1.8 for osteoarthritis Elife. DOI: 10.7554/Elife.57656.Sa2  0.525
2019 Tseng PY, Zheng Q, Li Z, Dong X. MrgprX1 Mediates Neuronal Excitability and Itch Through Tetrodotoxin-Resistant Sodium Channels. Itch (Philadelphia, Pa.). 4. PMID 33442562 DOI: 10.1097/itx.0000000000000028  0.573
2019 Ni S, Ling Z, Wang X, Cao Y, Wu T, Deng R, Crane JL, Skolask R, Demehril S, Zhen G, Jain A, Wu P, Pan D, Hu B, Lyu X, ... Dong X, et al. Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice. Nature Communications. 10: 5643. PMID 31822662 DOI: 10.1038/S41467-019-13476-9  0.628
2019 Tiwari V, He SQ, Huang Q, Liang L, Yang F, Chen Z, Tiwari V, Fujita W, Devi LA, Dong X, Guan Y, Raja SN. Activation of µ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents. Pain. PMID 31815916 DOI: 10.1097/J.Pain.0000000000001768  0.667
2019 Jall S, Finan B, Collden G, Fischer K, Dong X, Tschöp MH, Müller TD, Clemmensen C. Corrigendum to "Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice" [Molecular Metabolism 23 (2019) 75-81]. Molecular Metabolism. 30: 264. PMID 31767177 DOI: 10.1016/J.Molmet.2019.11.002  0.483
2019 Lei X, Liu L, Terrillion CE, Karuppagounder SS, Cisternas P, Lay M, Martinelli DC, Aja S, Dong X, Pletnikov MV, Wong GW. FAM19A1, a brain-enriched and metabolically responsive neurokine, regulates food intake patterns and mouse behaviors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901232RR. PMID 31689372 DOI: 10.1096/Fj.201901232Rr  0.582
2019 Serhan N, Basso L, Sibilano R, Petitfils C, Meixiong J, Bonnart C, Reber LL, Marichal T, Starkl P, Cenac N, Dong X, Tsai M, Galli SJ, Gaudenzio N. House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation. Nature Immunology. PMID 31591569 DOI: 10.1038/S41590-019-0493-Z  0.608
2019 Castro J, Harrington AM, Lieu T, Garcia-Caraballo S, Maddern J, Schober G, O'Donnell T, Grundy L, Lumsden AL, Miller PE, Ghetti A, Steinhoff MS, Poole DP, Dong X, Chang L, et al. Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivity. Jci Insight. PMID 31536477 DOI: 10.1172/Jci.Insight.131712  0.679
2019 Limjunyawong N, Dong X. Spicy Immunity: Pain to Gain. Immunity. 51: 426-428. PMID 31533055 DOI: 10.1016/J.Immuni.2019.08.014  0.552
2019 Prchalová E, Hin N, Thomas AG, Veeravalli V, Ng J, Alt J, Rais R, Rojas C, Li Z, Hihara H, Aoki M, Yoshizawa K, Nishioka T, Suzuki S, Kopajtic T, ... Dong X, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. Journal of Medicinal Chemistry. PMID 31498617 DOI: 10.1021/Acs.Jmedchem.9B01003  0.638
2019 Zhang T, Liu R, Che D, Pundir P, Wang N, Han S, Cao J, Lv Y, Dong H, Fang F, Wang J, Ma P, Zhao T, Lei T, Dong X, et al. A Mast Cell-Specific Receptor Is Critical for Granuloma Induced by Intrathecal Morphine Infusion. Journal of Immunology (Baltimore, Md. : 1950). PMID 31484729 DOI: 10.4049/Jimmunol.1801423  0.614
2019 Singh BK, Lu W, Schmidt Paustian AM, Ge MQ, Koziol-White CJ, Flayer CH, Killingbeck SS, Wang N, Dong X, Riese MJ, Deshpande DA, Panettieri RA, Haczku A, Kambayashi T. Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms. Science Signaling. 12. PMID 31481522 DOI: 10.1126/Scisignal.Aax3332  0.554
2019 Green D, Dong X. A Pungent and Painful Toxin. Cell. 178: 1279-1281. PMID 31474364 DOI: 10.1016/J.Cell.2019.08.016  0.552
2019 Abdus-Saboor I, Fried NT, Lay M, Burdge J, Swanson K, Fischer R, Jones J, Dong P, Cai W, Guo X, Tao YX, Bethea J, Ma M, Dong X, Ding L, et al. Development of a Mouse Pain Scale Using Sub-second Behavioral Mapping and Statistical Modeling. Cell Reports. 28: 1623-1634.e4. PMID 31390574 DOI: 10.1016/J.Celrep.2019.07.017  0.605
2019 Pundir P, Liu R, Vasavda C, Serhan N, Limjunyawong N, Yee R, Zhan Y, Dong X, Wu X, Zhang Y, Snyder SH, Gaudenzio N, Vidal JE, Dong X. A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity. Cell Host & Microbe. PMID 31278040 DOI: 10.1016/J.Chom.2019.06.003  0.594
2019 Wang L, Jiang X, Zheng Q, Jeon SM, Chen T, Liu Y, Kulaga H, Reed R, Dong X, Caterina MJ, Qu L. Neuronal FcγRI mediates acute and chronic joint pain. The Journal of Clinical Investigation. 130. PMID 31211699 DOI: 10.1172/Jci128010  0.65
2019 Chen Z, Wang T, Fang Y, Luo D, Anderson M, Huang Q, He S, Song X, Cui H, Dong X, Xie Y, Guan Y, Ma C. Adjacent intact nociceptive neurons drive the acute outburst of pain following peripheral axotomy. Scientific Reports. 9: 7651. PMID 31113988 DOI: 10.1038/S41598-019-44172-9  0.64
2019 Marchitto MC, Dillen CA, Liu H, Miller RJ, Archer NK, Ortines RV, Alphonse MP, Marusina AI, Merleev AA, Wang Y, Pinsker BL, Byrd AS, Brown ID, Ravipati A, Zhang E, ... Dong X, et al. Clonal Vγ6Vδ4 T cells promote IL-17-mediated immunity against skin infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31088972 DOI: 10.1073/Pnas.1818256116  0.533
2019 Meixiong J, Vasavda C, Snyder SH, Dong X. MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus. Proceedings of the National Academy of Sciences of the United States of America. PMID 31068464 DOI: 10.1073/Pnas.1903316116  0.662
2019 Syu GD, Wang SC, Ma G, Liu S, Pearce D, Prakash A, Henson B, Weng LC, Ghosh D, Ramos P, Eichinger D, Pino I, Dong X, Xiao J, Wang S, et al. Development and application of a high-content virion display human GPCR array. Nature Communications. 10: 1997. PMID 31040288 DOI: 10.1038/S41467-019-09938-9  0.571
2019 Meixiong J, Anderson M, Limjunyawong N, Sabbagh MF, Hu E, Mack MR, Oetjen LK, Wang F, Kim BS, Dong X. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch. Immunity. PMID 31027996 DOI: 10.1016/J.Immuni.2019.03.013  0.635
2019 Patel SP, Vasavda C, Ho B, Meixiong J, Dong X, Kwatra SG. Cholestatic pruritus: Emerging mechanisms and therapeutics. Journal of the American Academy of Dermatology. PMID 31009666 DOI: 10.1016/J.Jaad.2019.04.035  0.538
2019 Huang Y, Patil MJ, Yu M, Liptak P, Undem BJ, Dong X, Wang G, Yu S. Effects of ginger constituent 6-shogaol on gastroesophageal vagal afferent C-fibers. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13585. PMID 30947399 DOI: 10.1111/Nmo.13585  0.581
2019 Jall S, Finan B, Collden G, Fischer K, Dong X, Tschöp MH, Müller TD, Clemmensen C. Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice. Molecular Metabolism. PMID 30902502 DOI: 10.1016/J.Molmet.2019.02.011  0.518
2019 Xu Q, Dong X. Calcium imaging approaches in investigation of pain mechanism in the spinal cord. Experimental Neurology. PMID 30853387 DOI: 10.1016/j.expneurol.2019.03.002  0.553
2019 Patil MJ, Meeker S, Bautista D, Dong X, Undem BJ. Sphingosine-1-phosphate activates mouse vagal airway afferent C-fibres via S1PR3 receptors. The Journal of Physiology. PMID 30793318 DOI: 10.1113/Jp277521  0.595
2019 Green DP, Limjunyawong N, Gour N, Pundir P, Dong X. A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain. Neuron. PMID 30686732 DOI: 10.1016/J.Neuron.2019.01.012  0.621
2019 Meixiong J, Vasavda C, Green D, Zheng Q, Qi L, Kwatra SG, Hamilton JP, Snyder SH, Dong X. Identification of a bilirubin receptor may mediate a component of cholestatic itch. Elife. 8. PMID 30657454 DOI: 10.7554/Elife.44116  0.649
2019 Chen H, Hu B, Lv X, Zhu S, Zhen G, Wan M, Jain A, Gao B, Chai Y, Yang M, Wang X, Deng R, Wang L, Cao Y, Ni S, ... Dong X, et al. Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis. Nature Communications. 10: 181. PMID 30643142 DOI: 10.1038/S41467-018-08097-7  0.575
2019 Liu X, Wang H, Jiang Y, Zheng Q, Petrus M, Zhang M, Zheng S, Schmedt C, Dong X, Xiao B. STIM1 thermosensitivity defines the optimal preference temperature for warm sensation in mice. Cell Research. PMID 30607017 DOI: 10.1038/s41422-018-0129-0  0.526
2019 Meixiong J, Vasavda C, Green D, Zheng Q, Qi L, Kwatra SG, Hamilton JP, Snyder SH, Dong X. Author response: Identification of a bilirubin receptor that may mediate a component of cholestatic itch Elife. DOI: 10.7554/Elife.44116.027  0.582
2019 Huang Y, Patil MJ, Yu M, Undem B, Dong X, Yu S. Su1622 – Determine Ginger Constituent 6-Shogaol-Induced Effect on Gastroesophageal Vagal Afferent C-Fibers by Two-Photon Neuron Imaging and Extra-Cellular Single-Fiber Recording Gastroenterology. 156: S-586-S-587. DOI: 10.1016/S0016-5085(19)38361-1  0.552
2018 Zhu S, Zhu J, Zhen G, Hu Y, An S, Li Y, Zheng Q, Chen Z, Yang Y, Wan M, Skolasky RL, Cao Y, Wu T, Gao B, Yang M, ... Dong X, et al. Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain. The Journal of Clinical Investigation. PMID 30530994 DOI: 10.1172/Jci121561  0.615
2018 Shiratori-Hayashi M, Hasegawa A, Toyonaga H, Andoh T, Nakahara T, Kido-Nakahara M, Furue M, Kuraishi Y, Inoue K, Dong X, Tsuda M. Role of P2X3 receptors in scratching behavior in mouse models. The Journal of Allergy and Clinical Immunology. PMID 30452925 DOI: 10.1016/j.jaci.2018.10.053  0.603
2018 Salvatierra J, Diaz-Bustamante M, Meixiong J, Tierney E, Dong X, Bosmans F. A disease mutation reveals a role for NaV1.9 in acute itch. The Journal of Clinical Investigation. PMID 30395542 DOI: 10.1172/Jci122481  0.635
2018 Wang C, Gu L, Ruan Y, Geng X, Xu M, Yang N, Yu L, Jiang Y, Zhu C, Yang Y, Zhou Y, Guan X, Luo W, Liu Q, Dong X, et al. Facilitation of MrgprD by TRP-A1 promotes neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800615RR. PMID 30148678 DOI: 10.1096/Fj.201800615Rr  0.623
2018 Geng X, Shi H, Ye F, Du H, Qian L, Gu L, Wu G, Zhu C, Yang Y, Wang C, Zhou Y, Yu G, Liu Q, Dong X, Yu L, et al. Matrine inhibits itching by lowering the activity of calcium channel. Scientific Reports. 8: 11328. PMID 30054511 DOI: 10.1038/S41598-018-28661-X  0.586
2018 He SQ, Xu Q, Tiwari V, Yang F, Anderson M, Chen Z, Grenald SA, Raja SN, Dong X, Guan Y. Oligomerization of MrgC11 and μ-opioid receptors in sensory neurons enhances morphine analgesia. Science Signaling. 11. PMID 29921657 DOI: 10.1126/Scisignal.Aao3134  0.643
2018 Jain S, Panyutin A, Liu N, Xiao C, Piñol RA, Pundir P, Girardet C, Butler AA, Dong X, Gavrilova O, Reitman ML. Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors. American Journal of Physiology. Endocrinology and Metabolism. PMID 29812984 DOI: 10.1152/Ajpendo.00024.2018  0.616
2018 Dong X, Dong X. Peripheral and Central Mechanisms of Itch. Neuron. 98: 482-494. PMID 29723501 DOI: 10.1016/J.Neuron.2018.03.023  0.552
2018 Tiwari V, Anderson M, Yang F, Tiwari V, Zheng Q, He SQ, Zhang T, Shu B, Chen X, Grenald SA, Stephens KE, Chen Z, Dong X, Raja SN, Guan Y. Peripherally Acting μ-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats. Anesthesiology. PMID 29601322 DOI: 10.1097/Aln.0000000000002191  0.639
2018 Han L, Limjunyawong N, Ru F, Li Z, Hall OJ, Steele H, Zhu Y, Wilson J, Mitzner W, Kollarik M, Undem BJ, Canning BJ, Dong X. Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyper-responsiveness. Nature Neuroscience. PMID 29403029 DOI: 10.1038/S41593-018-0074-8  0.608
2018 Green D, Limjunyawong J, Dong X. The mast cell receptor mrgprb2 contributes to inflammatory pain via immune cell modulation The Journal of Pain. 19: S98. DOI: 10.1016/J.Jpain.2017.12.218  0.552
2018 Salvatierra J, Bosmans F, Diaz-Bustamante M, Meixiong J, Dong X. The Role NaV1.9 in Somatosensory Signaling Biophysical Journal. 114: 634a. DOI: 10.1016/J.Bpj.2017.11.3427  0.536
2017 Wang N, Che D, Zhang T, Liu R, Cao J, Wang J, Zhao T, Ma P, Dong X, He L. Saikosaponin A inhibits compound 48/80-induced pseudo-allergy via the Mrgprx2 pathway in vitro and in vivo. Biochemical Pharmacology. PMID 29274317 DOI: 10.1016/J.Bcp.2017.12.017  0.595
2017 Meixiong J, Dong X. Mas-Related G Protein-Coupled Receptors and the Biology of Itch Sensation. Annual Review of Genetics. 51: 103-121. PMID 29178819 DOI: 10.1146/Annurev-Genet-120116-024723  0.552
2017 Han S, Lv Y, Kong L, Che D, Liu R, Fu J, Cao J, Wang J, Wang C, He H, Zhang T, Dong X, He L. Use of the relative release index for histamine in LAD2 cells to evaluate the potential anaphylactoid effects of drugs. Scientific Reports. 7: 13714. PMID 29057927 DOI: 10.1038/S41598-017-14224-Z  0.539
2017 Miller RE, Kim YS, Tran PB, Ishihara S, Dong X, Miller RJ, Malfait AM. In vivo calcium imaging visualizes peripheral neuron sensitization in a surgical mouse model of osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28992367 DOI: 10.1002/Art.40342  0.622
2017 Liu R, Che D, Zhao T, Pundir P, Cao J, Lv Y, Wang J, Ma P, Fu J, Wang N, Wang X, Zhang T, Dong X, He L. MRGPRX2 is Essential for Sinomenine HydrochlorideInduced Anaphylactoid Reactions. Biochemical Pharmacology. PMID 28987593 DOI: 10.1016/J.Bcp.2017.09.017  0.594
2017 Wang J, Kollarik M, Ru F, Sun H, McNeil B, Dong X, Stephens G, Korolevich S, Brohawn P, Kolbeck R, Undem B. Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencing. Plos One. 12: e0185985. PMID 28982197 DOI: 10.1371/Journal.Pone.0185985  0.655
2017 Zhang T, Che D, Liu R, Han S, Wang N, Zhan Y, Pundir P, Cao J, Lv Y, Yang L, Wang J, Ding M, Dong X, He L. Typical antimicrobials induce mast cell degranulation and anaphylactoid reactions via MRGPRX2 and its murine homologue MRGPRB2. European Journal of Immunology. PMID 28688196 DOI: 10.1002/Eji.201746951  0.594
2017 Anderson M, Zheng Q, Dong X. Investigation of Pain Mechanisms by Calcium Imaging Approaches. Neuroscience Bulletin. PMID 28501905 DOI: 10.1007/S12264-017-0139-9  0.61
2017 Yuan X, Li Z, Baines AC, Gavriilaki E, Ye Z, Wen Z, Braunstein EM, Biesecker LG, Cheng L, Dong X, Brodsky RA. A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model. Plos One. 12: e0174074. PMID 28441409 DOI: 10.1371/Journal.Pone.0174074  0.59
2017 Weng YL, An R, Cassin J, Joseph J, Mi R, Wang C, Zhong C, Jin SG, Pfeifer GP, Bellacosa A, Dong X, Hoke A, He Z, Song H, Ming GL. An Intrinsic Epigenetic Barrier for Functional Axon Regeneration. Neuron. 94: 337-346.e6. PMID 28426967 DOI: 10.1016/J.Neuron.2017.03.034  0.587
2017 Kulkarni S, Micci MA, Leser J, Shin C, Tang SC, Fu YY, Liu L, Li Q, Saha M, Li C, Enikolopov G, Becker L, Rakhilin N, Anderson M, Shen X, Dong X, et al. Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28420791 DOI: 10.1073/Pnas.1619406114  0.612
2017 Salazar TE, Richardson MR, Beli E, Ripsch MS, George J, Kim Y, Duan Y, Moldovan L, Yan Y, Bhatwadekar A, Jadhav V, Smith JA, McGorray S, Bertone AL, Traktuev DO, ... Dong X, et al. Electroacupuncture Promotes CNS-Dependent Release of Mesenchymal Stem Cells. Stem Cells (Dayton, Ohio). PMID 28299842 DOI: 10.1002/Stem.2613  0.56
2017 Sun S, Xu Q, Guo C, Guan Y, Liu Q, Dong X. Leaky Gate Model: Intensity-Dependent Coding of Pain and Itch in the Spinal Cord. Neuron. 93: 840-853.e5. PMID 28231466 DOI: 10.1016/J.Neuron.2017.01.012  0.641
2017 Li Z, Tseng PY, Tiwari V, Xu Q, He SQ, Wang Y, Zheng Q, Han L, Wu Z, Blobaum AL, Cui Y, Tiwari V, Sun S, Cheng Y, Huang-Lionnet JH, ... Dong X, et al. Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223516 DOI: 10.1073/Pnas.1615255114  0.652
2017 Ru F, Sun H, Jurcakova D, Herbstsomer RA, Meixong J, Dong X, Undem BJ. Mechanisms of pruritogen-induced activation of itch nerves in isolated mouse skin. The Journal of Physiology. PMID 28217875 DOI: 10.1113/Jp273795  0.61
2017 Yu M, Liu S, Liu Y, Yu S, Hou X, Dong X, Yu X. MrgprC11 Expression and Function in Vagal Afferent Neurons in the Esophagus: A Novel Mechanism Underlying Visceral Sensation and Nociception Gastroenterology. 152: S211. DOI: 10.1016/S0016-5085(17)31009-0  0.552
2016 Green D, Dong X. (296) MRGB2 contributes to mechanical and thermal allodynia in an animal model of postoperative pain. The Journal of Pain : Official Journal of the American Pain Society. 17: S50. PMID 28162537 DOI: 10.1016/J.Jpain.2016.01.203  0.586
2016 Wang J, Xu W, Zhong T, Song Z, Zou Y, Ding Z, Guo Q, Dong X, Zou W. miR-365 targets β-arrestin 2 to reverse morphine tolerance in rats. Scientific Reports. 6: 38285. PMID 27922111 DOI: 10.1038/Srep38285  0.546
2016 Emery EC, Luiz AP, Sikandar S, Magnúsdóttir R, Dong X, Wood JN. In vivo characterization of distinct modality-specific subsets of somatosensory neurons using GCaMP. Science Advances. 2: e1600990. PMID 27847865 DOI: 10.1126/Sciadv.1600990  0.667
2016 Gaudenzio N, Sibilano R, Marichal T, Starkl P, Reber LL, Cenac N, McNeil BD, Dong X, Hernandez JD, Sagi-Eisenberg R, Hammel I, Roers A, Valitutti S, Tsai M, Espinosa E, et al. Different activation signals induce distinct mast cell degranulation strategies. The Journal of Clinical Investigation. PMID 27643442 DOI: 10.1172/Jci85538  0.575
2016 Yang F, Xu Q, Shu B, Tiwari V, He SQ, Vera-Portocarrero LP, Dong X, Linderoth B, Raja SN, Wang Y, Guan Y. Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation. Pain. PMID 27589093 DOI: 10.1097/J.Pain.0000000000000680  0.649
2016 Kim YS, Anderson M, Park K, Zheng Q, Agarwal A, Gong C, Saijilafu, Young L, He S, LaVinka PC, Zhou F, Bergles D, Hanani M, Guan Y, Spray DC, Dong X, et al. Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain. Neuron. PMID 27568517 DOI: 10.1016/J.Neuron.2016.07.044  0.66
2016 Oh Y, Cho GS, Li Z, Hong I, Zhu R, Kim MJ, Kim YJ, Tampakakis E, Tung L, Huganir R, Dong X, Kwon C, Lee G. Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons. Cell Stem Cell. PMID 27320040 DOI: 10.1016/J.Stem.2016.05.002  0.582
2016 Rakhilin N, Barth B, Choi J, Muñoz NL, Kulkarni S, Jones JS, Small DM, Cheng YT, Cao Y, LaVinka C, Kan E, Dong X, Spencer M, Pasricha P, Nishimura N, et al. Simultaneous optical and electrical in vivo analysis of the enteric nervous system. Nature Communications. 7: 11800. PMID 27270085 DOI: 10.1038/Ncomms11800  0.553
2016 Chang AY, Mann TS, McFawn PK, Han L, Dong X, Henry PJ. Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways. Respiratory Research. 17: 62. PMID 27215903 DOI: 10.1186/S12931-016-0378-8  0.612
2016 Green D, Dong X. The cell biology of acute itch. The Journal of Cell Biology. 213: 155-61. PMID 27114499 DOI: 10.1083/Jcb.201603042  0.552
2016 Tiwari V, Tiwari V, He S, Zhang T, Raja SN, Dong X, Guan Y. Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy. Advances in Experimental Medicine and Biology. 904: 87-103. PMID 26900065 DOI: 10.1007/978-94-017-7537-3_7  0.639
2016 Tang M, Wu G, Wang Z, Yang N, Shi H, He Q, Zhu C, Yang Y, Yu G, Wang C, Yuan X, Liu Q, Guan Y, Dong X, Tang Z. Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons. Brain Research. PMID 26874069 DOI: 10.1016/J.Brainres.2016.02.014  0.635
2016 Tiwari V, Yang F, He SQ, Shechter R, Zhang C, Shu B, Zhang T, Tiwari V, Wang Y, Dong X, Guan Y, Raja SN. Activation of Peripheral μ-opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) Amide Leads to Modality-preferred Inhibition of Neuropathic Pain. Anesthesiology. PMID 26756519 DOI: 10.1097/Aln.0000000000000993  0.609
2015 Sun S, Dong X. Trp channels and itch. Seminars in Immunopathology. PMID 26385480 DOI: 10.1007/S00281-015-0530-4  0.573
2015 Wang C, Wang Z, Yang Y, Zhu C, Wu G, Yu G, Jian T, Yang N, Shi H, Tang M, He Q, Lan L, Liu Q, Guan Y, Dong X, et al. Pirt contributes to uterine contraction-induced pain in mice. Molecular Pain. 11: 57. PMID 26376721 DOI: 10.1186/S12990-015-0054-X  0.672
2015 Green D, Dong X. Supporting itch: a new role for astrocytes in chronic itch. Nature Medicine. 21: 841-2. PMID 26248264 DOI: 10.1038/Nm.3921  0.552
2015 Reddy VB, Sun S, Azimi E, Elmariah SB, Dong X, Lerner EA. Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs. Nature Communications. 6: 7864. PMID 26216096 DOI: 10.1038/Ncomms8864  0.626
2015 Gao XF, Feng JF, Wang W, Xiang ZH, Liu XJ, Zhu C, Tang ZX, Dong XZ, He C. Pirt reduces bladder overactivity by inhibiting purinergic receptor P2X3. Nature Communications. 6: 7650. PMID 26151598 DOI: 10.1038/Ncomms8650  0.641
2015 Li Z, He SQ, Tseng PY, Xu Q, Tiwari V, Yang F, Shu B, Zhang T, Tang Z, Raja SN, Wang Y, Dong X, Guan Y. The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms. Neuroscience. 300: 393-403. PMID 26022362 DOI: 10.1016/J.Neuroscience.2015.05.043  0.649
2015 Sdrulla AD, Xu Q, He SQ, Tiwari V, Yang F, Zhang C, Shu B, Shechter R, Raja SN, Wang Y, Dong X, Guan Y. Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice. Pain. 156: 1008-17. PMID 25974163 DOI: 10.1097/01.J.Pain.0000460353.15460.A3  0.631
2015 Liu Q, Dong X. The role of the Mrgpr receptor family in itch. Handbook of Experimental Pharmacology. 226: 71-88. PMID 25861775 DOI: 10.1007/978-3-662-44605-8_5  0.657
2015 Pang Z, Sakamoto T, Tiwari V, Kim YS, Yang F, Dong X, Güler AD, Guan Y, Caterina MJ. Selective keratinocyte stimulation is sufficient to evoke nociception in mice. Pain. 156: 656-65. PMID 25790456 DOI: 10.1097/J.Pain.0000000000000092  0.634
2015 Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 85: 833-46. PMID 25640077 DOI: 10.1016/J.Neuron.2014.12.065  0.629
2015 McNeil BD, Pundir P, Meeker S, Han L, Undem BJ, Kulka M, Dong X. Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions. Nature. 519: 237-41. PMID 25517090 DOI: 10.1038/Nature14022  0.606
2015 Yang F, Zhang C, Xu Q, Tiwari V, He SQ, Wang Y, Dong X, Vera-Portocarrero LP, Wacnik PW, Raja SN, Guan Y. Electrical stimulation of dorsal root entry zone attenuates wide-dynamic-range neuronal activity in rats. Neuromodulation : Journal of the International Neuromodulation Society. 18: 33-40; discussion 40. PMID 25308522 DOI: 10.1111/Ner.12249  0.642
2015 Wen W, Wang Y, Li Z, Tseng PY, McManus OB, Wu M, Li M, Lindsley CW, Dong X, Hopkins CR. Discovery and characterization of 2-(cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide, ML382: a potent and selective positive allosteric modulator of MrgX1. Chemmedchem. 10: 57-61. PMID 25209672 DOI: 10.1002/Cmdc.201402277  0.617
2015 Green D, Dong X. Supporting itch: A new role for astrocytes in chronic itch Nature Medicine. 21: 841-842. DOI: 10.1038/nm.3921  0.503
2015 Reddy VB, Sun S, Azimi E, Elmariah SB, Dong X, Lerner EA. Redefining the concept of protease-activated receptors: Cathepsin S evokes itch via activation of Mrgprs Nature Communications. 6. DOI: 10.1038/ncomms8864  0.534
2015 Xu Q, Yang F, Sdrulla A, Raja S, Dong X, Guan Y. (351) Electrophysiologic mechanisms of “pain gating” in the superficial dorsal horn by activation of low-threshold afferent fibers The Journal of Pain. 16: S63. DOI: 10.1016/J.Jpain.2015.01.269  0.564
2015 Miller R, Park K, Ishihara S, Kim Y, Miller R, Dong X, Malfait A. In vivo calcium imaging of knee-innervating dorsal root ganglion neurons reveals increased neuronal responsiveness to physical stimuli after dmm surgery Osteoarthritis and Cartilage. 23: A61. DOI: 10.1016/J.Joca.2015.02.127  0.61
2014 Hin N, Alt J, Zimmermann SC, Delahanty G, Ferraris DV, Rojas C, Li F, Liu Q, Dong X, Slusher BS, Tsukamoto T. Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors. Bioorganic & Medicinal Chemistry. 22: 5831-7. PMID 25288495 DOI: 10.1016/J.Bmc.2014.09.025  0.589
2014 Kim YJ, Lim H, Li Z, Oh Y, Kovlyagina I, Choi IY, Dong X, Lee G. Generation of multipotent induced neural crest by direct reprogramming of human postnatal fibroblasts with a single transcription factor. Cell Stem Cell. 15: 497-506. PMID 25158936 DOI: 10.1016/J.Stem.2014.07.013  0.535
2014 Miskimon M, Han S, Lee JJ, Ringkamp M, Wilson MA, Petralia RS, Dong X, Worley PF, Baraban JM, Reti IM. Selective expression of Narp in primary nociceptive neurons: role in microglia/macrophage activation following nerve injury. Journal of Neuroimmunology. 274: 86-95. PMID 25005116 DOI: 10.1016/J.Jneuroim.2014.06.016  0.669
2014 Wooten M, Weng HJ, Hartke TV, Borzan J, Klein AH, Turnquist B, Dong X, Meyer RA, Ringkamp M. Three functionally distinct classes of C-fibre nociceptors in primates. Nature Communications. 5: 4122. PMID 24947823 DOI: 10.1038/Ncomms5122  0.601
2014 Boitano S, Hoffman J, Tillu DV, Asiedu MN, Zhang Z, Sherwood CL, Wang Y, Dong X, Price TJ, Vagner J. Development and evaluation of small peptidomimetic ligands to protease-activated receptor-2 (PAR2) through the use of lipid tethering. Plos One. 9: e99140. PMID 24927179 DOI: 10.1371/Journal.Pone.0099140  0.594
2014 Han L, Dong X. Itch mechanisms and circuits. Annual Review of Biophysics. 43: 331-55. PMID 24819620 DOI: 10.1146/Annurev-Biophys-051013-022826  0.566
2014 Li Z, He SQ, Xu Q, Yang F, Tiwari V, Liu Q, Tang Z, Han L, Chu YX, Wang Y, Hin N, Tsukamoto T, Slusher B, Guan X, Wei F, ... Dong X, et al. Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice. Pain. 155: 1613-21. PMID 24813294 DOI: 10.1016/J.Pain.2014.05.008  0.694
2014 Qu L, Fan N, Ma C, Wang T, Han L, Fu K, Wang Y, Shimada SG, Dong X, LaMotte RH. Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain. Brain : a Journal of Neurology. 137: 1039-50. PMID 24549959 DOI: 10.1093/Brain/Awu007  0.668
2014 Kim YS, Chu Y, Han L, Li M, Li Z, Lavinka PC, Sun S, Tang Z, Park K, Caterina MJ, Ren K, Dubner R, Wei F, Dong X. Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain. Neuron. 81: 873-87. PMID 24462040 DOI: 10.1016/J.Neuron.2013.12.011  0.657
2014 Yang F, Xu Q, Cheong YK, Shechter R, Sdrulla A, He SQ, Tiwari V, Dong X, Wacnik PW, Meyer R, Raja SN, Guan Y. Comparison of intensity-dependent inhibition of spinal wide-dynamic range neurons by dorsal column and peripheral nerve stimulation in a rat model of neuropathic pain. European Journal of Pain (London, England). 18: 978-88. PMID 24390782 DOI: 10.1002/J.1532-2149.2013.00443.X  0.641
2014 He SQ, Han L, Li Z, Xu Q, Tiwari V, Yang F, Guan X, Wang Y, Raja SN, Dong X, Guan Y. Temporal changes in MrgC expression after spinal nerve injury. Neuroscience. 261: 43-51. PMID 24374082 DOI: 10.1016/J.Neuroscience.2013.12.041  0.66
2014 LaMotte RH, Dong X, Ringkamp M. Sensory neurons and circuits mediating itch. Nature Reviews. Neuroscience. 15: 19-31. PMID 24356071 DOI: 10.1038/Nrn3641  0.657
2014 He SQ, Li Z, Chu YX, Han L, Xu Q, Li M, Yang F, Liu Q, Tang Z, Wang Y, Hin N, Tsukamoto T, Slusher B, Tiwari V, Shechter R, ... Dong X, et al. MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain. Pain. 155: 534-44. PMID 24333779 DOI: 10.1016/J.Pain.2013.12.008  0.683
2014 Kim YS, Chu Y, Han L, Park K, Li M, Li Z, LaVinka P, Caterina MJ, Ren K, Dubner R, Wei F, Dong X. Imaging orofacial pain in mice Molecular Pain. 10: O2. DOI: 10.1186/1744-8069-10-S1-O2  0.675
2013 Shechter R, Yang F, Xu Q, Cheong YK, He SQ, Sdrulla A, Carteret AF, Wacnik PW, Dong X, Meyer RA, Raja SN, Guan Y. Conventional and kilohertz-frequency spinal cord stimulation produces intensity- and frequency-dependent inhibition of mechanical hypersensitivity in a rat model of neuropathic pain. Anesthesiology. 119: 422-32. PMID 23880991 DOI: 10.1097/Aln.0B013E31829Bd9E2  0.603
2013 He SQ, Yang F, Perez FM, Xu Q, Shechter R, Cheong YK, Carteret AF, Dong X, Sweitzer SM, Raja SN, Guan Y. Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats. Pain. 154: 2477-86. PMID 23880055 DOI: 10.1016/J.Pain.2013.07.023  0.609
2013 Tang Z, Kim A, Masuch T, Park K, Weng H, Wetzel C, Dong X. Pirt functions as an endogenous regulator of TRPM8. Nature Communications. 4: 2179. PMID 23863968 DOI: 10.1038/Ncomms3179  0.64
2013 Zhao X, Tang Z, Zhang H, Atianjoh FE, Zhao JY, Liang L, Wang W, Guan X, Kao SC, Tiwari V, Gao YJ, Hoffman PN, Cui H, Li M, Dong X, et al. A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons. Nature Neuroscience. 16: 1024-31. PMID 23792947 DOI: 10.1038/Nn.3438  0.624
2013 Han L, Ma C, Liu Q, Weng HJ, Cui Y, Tang Z, Kim Y, Nie H, Qu L, Patel KN, Li Z, McNeil B, He S, Guan Y, Xiao B, ... Dong X, et al. A subpopulation of nociceptors specifically linked to itch. Nature Neuroscience. 16: 174-82. PMID 23263443 DOI: 10.1038/Nn.3289  0.664
2012 Liu Q, Sikand P, Ma C, Tang Z, Han L, Li Z, Sun S, LaMotte RH, Dong X. Mechanisms of itch evoked by β-alanine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14532-7. PMID 23077038 DOI: 10.1523/Jneurosci.3509-12.2012  0.663
2012 Liu T, Berta T, Xu ZZ, Park CK, Zhang L, Lü N, Liu Q, Liu Y, Gao YJ, Liu YC, Ma Q, Dong X, Ji RR. TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. The Journal of Clinical Investigation. 122: 2195-207. PMID 22565312 DOI: 10.1172/Jci45414  0.758
2012 Hu JH, Yang L, Kammermeier PJ, Moore CG, Brakeman PR, Tu J, Yu S, Petralia RS, Li Z, Zhang PW, Park JM, Dong X, Xiao B, Worley PF. Preso1 dynamically regulates group I metabotropic glutamate receptors. Nature Neuroscience. 15: 836-44. PMID 22561452 DOI: 10.1038/Nn.3103  0.587
2012 Chung C, Carteret AF, McKelvy AD, Ringkamp M, Yang F, Hartke TV, Dong X, Raja SN, Guan Y. Analgesic properties of loperamide differ following systemic and local administration to rats after spinal nerve injury. European Journal of Pain (London, England). 16: 1021-32. PMID 22508374 DOI: 10.1002/J.1532-2149.2012.00148.X  0.579
2012 McNeil B, Dong X. Peripheral mechanisms of itch. Neuroscience Bulletin. 28: 100-10. PMID 22466121 DOI: 10.1007/S12264-012-1202-1  0.552
2011 Yang F, Carteret AF, Wacnik PW, Chung CY, Xing L, Dong X, Meyer RA, Raja SN, Guan Y. Bipolar spinal cord stimulation attenuates mechanical hypersensitivity at an intensity that activates a small portion of A-fiber afferents in spinal nerve-injured rats. Neuroscience. 199: 470-80. PMID 22001681 DOI: 10.1016/J.Neuroscience.2011.09.049  0.598
2011 Liu Q, Weng HJ, Patel KN, Tang Z, Bai H, Steinhoff M, Dong X. The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia. Science Signaling. 4: ra45. PMID 21775281 DOI: 10.1126/Scisignal.2001925  0.666
2011 Patel KN, Dong X. Itch: Cells, Molecules, and Circuits. Acs Chemical Neuroscience. 2: 17-25. PMID 21720568 DOI: 10.1021/Cn100085G  0.558
2011 Patel KN, Liu Q, Meeker S, Undem BJ, Dong X. Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch. Plos One. 6: e20559. PMID 21655234 DOI: 10.1371/Journal.Pone.0020559  0.628
2011 Sikand P, Dong X, LaMotte RH. BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7563-7. PMID 21593341 DOI: 10.1523/Jneurosci.1192-11.2011  0.604
2011 Wilson SR, Gerhold KA, Bifolck-Fisher A, Liu Q, Patel KN, Dong X, Bautista DM. TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch. Nature Neuroscience. 14: 595-602. PMID 21460831 DOI: 10.1038/Nn.2789  0.664
2010 Patel KN, Dong X. An itch to be scratched. Neuron. 68: 334-9. PMID 21040839 DOI: 10.1016/J.Neuron.2010.10.018  0.542
2010 Guan Y, Liu Q, Tang Z, Raja SN, Anderson DJ, Dong X. Mas-related G-protein-coupled receptors inhibit pathological pain in mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 15933-8. PMID 20724664 DOI: 10.1073/Pnas.1011221107  0.713
2009 Liu Q, Tang Z, Surdenikova L, Kim S, Patel KN, Kim A, Ru F, Guan Y, Weng HJ, Geng Y, Undem BJ, Kollarik M, Chen ZF, Anderson DJ, Dong X. Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus. Cell. 139: 1353-65. PMID 20004959 DOI: 10.1016/J.Cell.2009.11.034  0.802
2008 Kim AY, Tang Z, Liu Q, Patel KN, Maag D, Geng Y, Dong X. Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. Cell. 133: 475-85. PMID 18455988 DOI: 10.1016/J.Cell.2008.02.053  0.639
2008 Lee MG, Dong X, Liu Q, Patel KN, Choi OH, Vonakis B, Undem BJ. Agonists of the MAS-related gene (Mrgs) orphan receptors as novel mediators of mast cell-sensory nerve interactions. Journal of Immunology (Baltimore, Md. : 1950). 180: 2251-5. PMID 18250432 DOI: 10.4049/Jimmunol.180.4.2251  0.611
2008 Liu Y, Yang FC, Okuda T, Dong X, Zylka MJ, Chen CL, Anderson DJ, Kuner R, Ma Q. Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 125-32. PMID 18171930 DOI: 10.1523/Jneurosci.4472-07.2008  0.795
2007 Liu Q, Vrontou S, Rice FL, Zylka MJ, Dong X, Anderson DJ. Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch. Nature Neuroscience. 10: 946-8. PMID 17618277 DOI: 10.1038/Nn1937  0.76
2007 Fiacco TA, Agulhon C, Taves SR, Petravicz J, Casper KB, Dong X, Chen J, McCarthy KD. Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity. Neuron. 54: 611-26. PMID 17521573 DOI: 10.1016/J.Neuron.2007.04.032  0.615
2003 Zylka MJ, Dong X, Southwell AL, Anderson DJ. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Proceedings of the National Academy of Sciences of the United States of America. 100: 10043-8. PMID 12909716 DOI: 10.1073/Pnas.1732949100  0.811
2002 Han SK, Dong X, Hwang JI, Zylka MJ, Anderson DJ, Simon MI. Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway. Proceedings of the National Academy of Sciences of the United States of America. 99: 14740-5. PMID 12397184 DOI: 10.1073/Pnas.192565799  0.771
2001 Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 106: 619-32. PMID 11551509 DOI: 10.1016/S0092-8674(01)00483-4  0.794
1999 Dong X, Tsuda L, Zavitz KH, Lin M, Li S, Carthew RW, Zipursky SL. ebi regulates epidermal growth factor receptor signaling pathways in Drosophila. Genes & Development. 13: 954-65. PMID 10215623 DOI: 10.1101/Gad.13.8.954  0.578
1998 Jackson GR, Salecker I, Dong X, Yao X, Arnheim N, Faber PW, MacDonald ME, Zipursky SL. Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron. 21: 633-42. PMID 9768849 DOI: 10.1016/S0896-6273(00)80573-5  0.617
1997 Thomas BJ, Zavitz KH, Dong X, Lane ME, Weigmann K, Finley RL, Brent R, Lehner CF, Zipursky SL. roughex down-regulates G2 cyclins in G1. Genes & Development. 11: 1289-98. PMID 9171373 DOI: 10.1101/Gad.11.10.1289  0.542
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