Srinivasa N. Raja - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 

202 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Berhane I, Hin N, Thomas AG, Huang Q, Zhang C, Veeravalli V, Wu Y, Ng J, Alt J, Rojas C, Hihara H, Aoki M, Yoshizawa K, Nishioka T, Suzuki S, ... ... Raja SN, et al. Thieno[2,3-]pyrimidine-Based Positive Allosteric Modulators of Human Mas-Related G Protein-Coupled Receptor X1 (MRGPRX1). Journal of Medicinal Chemistry. PMID 35119273 DOI: 10.1021/acs.jmedchem.1c01709  0.337
2021 Ford NC, Barpujari A, He SQ, Huang Q, Zhang C, Dong X, Guan Y, Raja SN. Role of primary sensory neurone cannabinoid type-1 receptors in pain and the analgesic effects of the peripherally acting agonist CB-13 in mice. British Journal of Anaesthesia. PMID 34844727 DOI: 10.1016/j.bja.2021.10.020  0.809
2021 Schwartz SM, Barpujari A, Finnerup NB, Raja SN. Pharmacologic therapies for neuropathic pain: an assessment of reporting biases in randomized controlled trials. Pain. PMID 34348355 DOI: 10.1097/j.pain.0000000000002426  0.789
2021 Gewandter JS, Dworkin RH, Turk DC, Farrar JT, Fillingim RB, Gilron I, Markman JD, Oaklander AL, Polydefkis MJ, Raja SN, Robinson JP, Woolf CJ, Ziegler D, Ashburn MA, Burke LB, et al. Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations. Pain Reports. 6: e895. PMID 33981929 DOI: 10.1097/PR9.0000000000000895  0.364
2021 Doshi TL, Dworkin RH, Polomano RC, Carr DB, Edwards RR, Finnerup NB, Freeman RL, Paice JA, Weisman SJ, Raja SN. AAAPT Diagnostic Criteria for Acute Neuropathic Pain. Pain Medicine (Malden, Mass.). PMID 33575803 DOI: 10.1093/pm/pnaa407  0.385
2020 Raja SN, Ringkamp M, Guan Y, Campbell JN. John J. Bonica Award Lecture: Peripheral neuronal hyperexcitability: the "low-hanging" target for safe therapeutic strategies in neuropathic pain. Pain. 161: S14-S26. PMID 33090736 DOI: 10.1097/J.Pain.0000000000001838  0.59
2020 Barpujari A, Ford N, He SQ, Huang Q, Gaveriaux-Ruff C, Dong X, Guan Y, Raja S. Role of peripheral sensory neuron mu-opioid receptors in nociceptive, inflammatory, and neuropathic pain. Regional Anesthesia and Pain Medicine. PMID 32928995 DOI: 10.1136/Rapm-2020-101779  0.814
2020 Doshi TL, Nixdorf DR, Campbell CM, Raja SN. Biomarkers in Temporomandibular Disorder and Trigeminal Neuralgia: A Conceptual Framework for Understanding Chronic Pain. Canadian Journal of Pain = Revue Canadienne De La Douleur. 4: 1-18. PMID 32923920 DOI: 10.1080/24740527.2019.1709163  0.38
2020 Raja SN, Carr DB, Cohen M, Finnerup NB, Flor H, Gibson S, Keefe FJ, Mogil JS, Ringkamp M, Sluka KA, Song XJ, Stevens B, Sullivan MD, Tutelman PR, Ushida T, et al. The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises. Pain. PMID 32694387 DOI: 10.1097/J.Pain.0000000000001939  0.456
2020 Smith SM, Dworkin RH, Turk DC, McDermott M, Eccleston C, Farrar JT, Rowbotham MC, Bhangwagar Z, Burke LB, Cowan P, Ellenberg SS, Evans SR, Freeman RL, Garrison LP, Iyengar S, ... ... Raja SN, et al. Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations. Pain. PMID 32520773 DOI: 10.1097/J.Pain.0000000000001952  0.329
2019 Hoydonckx Y, Kumar P, Flamer D, Costanzi M, Raja SN, Peng P, Bhatia A. Quality of Chronic Pain Interventional Treatment guidelines from Pain Societies: Assessment with the AGREE II instrument. European Journal of Pain (London, England). PMID 31880843 DOI: 10.1002/ejp.1524  0.427
2019 Tiwari V, He SQ, Huang Q, Liang L, Yang F, Chen Z, Tiwari V, Fujita W, Devi LA, Dong X, Guan Y, Raja SN. Activation of µ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents. Pain. PMID 31815916 DOI: 10.1097/J.Pain.0000000000001768  0.513
2019 Campbell CM, Gilron I, Doshi T, Raja S. Designing and conducting proof-of-concept chronic pain analgesic clinical trials. Pain Reports. 4: e697. PMID 31583338 DOI: 10.1097/PR9.0000000000000697  0.362
2019 Liu S, Huang Q, He S, Chen Z, Gao X, Ma D, Duan W, Ford N, Yang F, Chen X, Raja SN, Hao D, Guan Y. Dermorphin [D-Arg2, Lys4] (1-4) amide inhibits below-level heat hypersensitivity in mice after contusive thoracic spinal cord injury. Pain. PMID 31365470 DOI: 10.1097/J.Pain.0000000000001671  0.404
2019 Duan W, Huang Q, Chen Z, Raja SN, Yang F, Guan Y. Comparisons of motor and sensory abnormalities after lumbar and thoracic contusion spinal cord injury in male rats. Neuroscience Letters. 134358. PMID 31269465 DOI: 10.1016/J.Neulet.2019.134358  0.311
2019 Raja SN, Sivanesan E, Guan Y. Central Sensitization, N-methyl-D-aspartate Receptors, and Human Experimental Pain Models: Bridging the Gap between Target Discovery and Drug Development. Anesthesiology. PMID 31233408 DOI: 10.1097/Aln.0000000000002808  0.372
2019 Yang F, Duan W, Huang Q, Chen Z, Ford N, Gao X, Sivanesan E, Sarma SV, Vera-Portocarrero LP, Linderoth B, Raja SN, Guan Y. Modulation of Spinal Nociceptive Transmission by Sub-Sensory Threshold Spinal Cord Stimulation in Rats After Nerve Injury. Neuromodulation : Journal of the International Neuromodulation Society. PMID 31162783 DOI: 10.1111/Ner.12975  0.381
2019 Scholz J, Finnerup NB, Attal N, Aziz Q, Baron R, Bennett MI, Benoliel R, Cohen M, Cruccu G, Davis KD, Evers S, First M, Giamberardino MA, Hansson P, Kaasa S, ... ... Raja SN, et al. The IASP classification of chronic pain for ICD-11: chronic neuropathic pain. Pain. 160: 53-59. PMID 30586071 DOI: 10.1097/J.Pain.0000000000001365  0.641
2018 Sivanesan E, Maher DP, Raja SN, Linderoth B, Guan Y. Supraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain: Five Decades of Research and Prospects for the Future. Anesthesiology. PMID 30556812 DOI: 10.1097/Aln.0000000000002353  0.443
2018 Chen Z, Huang Q, Yang F, Shi C, Sivanesan E, Liu S, Chen X, Sarma SV, Vera-Portocarrero LP, Linderoth B, Raja SN, Guan Y. The Impact of Electrical Charge Delivery on Inhibition of Mechanical Hypersensitivity in Nerve-Injured Rats by Sub-Sensory Threshold Spinal Cord Stimulation. Neuromodulation : Journal of the International Neuromodulation Society. PMID 30556616 DOI: 10.1111/Ner.12910  0.452
2018 Stephens K, Chen Z, Sivanesan E, Raja S, Linderoth B, Tavernn SD, Guan Y. [EXPRESS] RNA-seq of Spinal Cord in Nerve-injured Rats after Spinal Cord Stimulation. Molecular Pain. 1744806918817429. PMID 30451078 DOI: 10.1177/1744806918817429  0.402
2018 Finnerup NB, Haroutounian S, Baron R, Dworkin RH, Gilron I, Haanpaa M, Jensen TS, Kamerman PR, McNicol E, Moore A, Raja SN, Andersen NT, Sena ES, Smith BH, Rice AS, et al. Neuropathic Pain Clinical Trials: Factors Associated with Decreases in Estimated Drug Efficacy. Pain. PMID 30015707 DOI: 10.1097/j.pain.0000000000001340  0.413
2018 He SQ, Xu Q, Tiwari V, Yang F, Anderson M, Chen Z, Grenald SA, Raja SN, Dong X, Guan Y. Oligomerization of MrgC11 and μ-opioid receptors in sensory neurons enhances morphine analgesia. Science Signaling. 11. PMID 29921657 DOI: 10.1126/Scisignal.Aao3134  0.364
2018 Yang F, Anderson M, He S, Stephens K, Zheng Y, Chen Z, Raja SN, Aplin F, Guan Y, Fridman G. Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current. Science Advances. 4: eaaq1438. PMID 29651458 DOI: 10.1126/Sciadv.Aaq1438  0.307
2018 Tiwari V, Anderson M, Yang F, Tiwari V, Zheng Q, He SQ, Zhang T, Shu B, Chen X, Grenald SA, Stephens KE, Chen Z, Dong X, Raja SN, Guan Y. Peripherally Acting μ-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats. Anesthesiology. PMID 29601322 DOI: 10.1097/Aln.0000000000002191  0.491
2018 Sdrulla AD, Guan Y, Raja SN. Spinal Cord Stimulation: Clinical Efficacy and Potential Mechanisms. Pain Practice : the Official Journal of World Institute of Pain. PMID 29526043 DOI: 10.1111/Papr.12692  0.432
2018 Bhatnagar S, Patel A, Raja SN. Aspiring Pain Practitioners in India: Assessing Challenges and Building Opportunities. Indian Journal of Palliative Care. 24: 93-97. PMID 29440815 DOI: 10.4103/IJPC.IJPC_148_17  0.476
2018 Klein AH, Mohammad HK, Ali R, Peper B, Wilson SP, Raja SN, Ringkamp M, Sweitzer S. Overexpression of µ-Opioid Receptors in Peripheral Afferents, but Not in Combination with Enkephalin, Decreases Neuropathic Pain Behavior and Enhances Opioid Analgesia in Mouse. Anesthesiology. PMID 29334500 DOI: 10.1097/Aln.0000000000002063  0.447
2018 Grenald S, Guan Y, Raja S. Peripheral cannabinoid and mu opioid receptor synergistic inhibition of neuropathic pain The Journal of Pain. 19: S74. DOI: 10.1016/J.Jpain.2017.12.169  0.35
2017 Walco GA, Kopecky EA, Weisman SJ, Stinson J, Stevens B, Desjardins PJ, Berde CB, Krane EJ, Anand KJ, Yaster M, Dampier CD, Dworkin RH, Gilron I, Lynn AM, Maxwell LG, ... Raja S, et al. Clinical trial designs and models for analgesic medications for acute pain in neonates, infants, toddlers, children, and adolescents: ACTTION recommendations. Pain. PMID 29140927 DOI: 10.1097/J.Pain.0000000000001104  0.395
2017 Smith BH, Raja SN. NeuPSIG: investing in solutions to the growing global challenge of neuropathic pain. British Journal of Anaesthesia. 119: 705-708. PMID 29121305 DOI: 10.1093/bja/aex276  0.441
2017 Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, ... ... Raja S, et al. The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions. The Journal of Pain : Official Journal of the American Pain Society. 18: 479-489. PMID 28495013 DOI: 10.1016/J.Jpain.2017.02.421  0.382
2017 Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, ... ... Raja S, et al. The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions. Pain Medicine (Malden, Mass.). PMID 28482098 DOI: 10.1093/Pm/Pnx019  0.38
2017 Castillo RC, Raja SN, Frey KP, Vallier HA, Tornetta P, Jaeblon T, Goff BJ, Gottschalk A, Scharfstein DO, OʼToole RV. Improving Pain Management and Long-Term Outcomes Following High-Energy Orthopaedic Trauma (Pain Study). Journal of Orthopaedic Trauma. 31: S71-S77. PMID 28323806 DOI: 10.1097/Bot.0000000000000793  0.469
2017 Smith SM, Dworkin RH, Turk DC, Baron R, Polydefkis M, Tracey I, Borsook D, Edwards RR, Harris RE, Wager TD, Arendt-Nielsen L, Burke LB, Carr DB, Chappell A, Farrar JT, ... ... Raja SN, et al. The potential role of sensory testing, skin biopsy, and functional brain imaging as biomarkers in chronic pain clinical trials: IMMPACT considerations. The Journal of Pain : Official Journal of the American Pain Society. PMID 28254585 DOI: 10.1016/J.Jpain.2017.02.429  0.398
2017 Li Z, Tseng PY, Tiwari V, Xu Q, He SQ, Wang Y, Zheng Q, Han L, Wu Z, Blobaum AL, Cui Y, Tiwari V, Sun S, Cheng Y, Huang-Lionnet JH, ... ... Raja SN, et al. Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223516 DOI: 10.1073/Pnas.1615255114  0.489
2017 Colloca L, Ludman T, Bouhassira D, Baron R, Dickenson AH, Yarnitsky D, Freeman R, Truini A, Attal N, Finnerup NB, Eccleston C, Kalso E, Bennett DL, Dworkin RH, Raja SN. Neuropathic pain. Nature Reviews. Disease Primers. 3: 17002. PMID 28205574 DOI: 10.1038/nrdp.2017.2  0.399
2017 Rothstein D, Kitt RA, Smith SM, Abdi S, Engle MP, McDermott MP, Raja SN, Turk DC, Dworkin RH, Gewandter JS. Reporting of Design Features and Analysis Details in Randomized Clinical Trials of Procedural Treatments for Cancer Pain: An ACTTION Systematic Review. Regional Anesthesia and Pain Medicine. PMID 28085789 DOI: 10.1097/Aap.0000000000000553  0.381
2016 Polsunas PJ, Sowa G, Fritz JM, Gentili A, Morone NE, Raja SN, Rodriguez E, Schmader K, Scholten JD, Weiner DK. Deconstructing Chronic Low Back Pain in the Older Adult-Step by Step Evidence and Expert-Based Recommendations for Evaluation and Treatment: Part X: Sacroiliac Joint Syndrome. Pain Medicine (Malden, Mass.). 17: 1638-47. PMID 27605679 DOI: 10.1093/Pm/Pnw151  0.411
2016 Yang F, Xu Q, Shu B, Tiwari V, He SQ, Vera-Portocarrero LP, Dong X, Linderoth B, Raja SN, Wang Y, Guan Y. Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation. Pain. PMID 27589093 DOI: 10.1097/J.Pain.0000000000000680  0.409
2016 Williams MR, McKeown A, Pressman Z, Hunsinger M, Lee K, Coplan P, Gilron I, Katz NP, McDermott MP, Raja SN, Rappaport BA, Rowbotham MC, Turk DC, Dworkin RH, Smith SM. Adverse event reporting in clinical trials of intravenous and invasive pain treatments: an ACTTION systematic review. The Journal of Pain : Official Journal of the American Pain Society. PMID 27522950 DOI: 10.1016/J.Jpain.2016.07.006  0.35
2016 Finnerup NB, Haroutounian S, Kamerman P, Baron R, Bennett DL, Bouhassira D, Cruccu G, Freeman R, Hansson P, Nurmikko T, Raja SN, Rice AS, Serra J, Smith BH, Treede RD, et al. Neuropathic pain: An updated grading system for research and clinical practice. Pain. PMID 27115670 DOI: 10.1097/j.pain.0000000000000492  0.394
2016 Tiwari V, Tiwari V, He S, Zhang T, Raja SN, Dong X, Guan Y. Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy. Advances in Experimental Medicine and Biology. 904: 87-103. PMID 26900065 DOI: 10.1007/978-94-017-7537-3_7  0.442
2016 Tiwari V, Yang F, He SQ, Shechter R, Zhang C, Shu B, Zhang T, Tiwari V, Wang Y, Dong X, Guan Y, Raja SN. Activation of Peripheral μ-opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) Amide Leads to Modality-preferred Inhibition of Neuropathic Pain. Anesthesiology. PMID 26756519 DOI: 10.1097/Aln.0000000000000993  0.461
2015 Cooper SA, Desjardins PJ, Turk DC, Dworkin RH, Katz NP, Kehlet H, Ballantyne JC, Burke LB, Carragee E, Cowan P, Croll S, Dionne RA, Farrar JT, Gilron I, Gordon DB, ... ... Raja SN, et al. Research design considerations for single-dose analgesic clinical trials in acute pain: IMMPACT recommendations. Pain. PMID 26683233 DOI: 10.1097/J.Pain.0000000000000375  0.419
2015 van Hecke O, Kamerman PR, Attal N, Baron R, Bjornsdottir G, Bennett DL, Bennett MI, Bouhassira D, Diatchenko L, Freeman R, Freynhagen R, Haanpää M, Jensen TS, Raja SN, Rice AS, et al. Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations. Pain. 156: 2337-53. PMID 26469320 DOI: 10.1097/J.Pain.0000000000000335  0.458
2015 Yang F, Zhang T, Tiwari V, Shu B, Zhang C, Wang Y, Vera-Portocarrero LP, Raja SN, Guan Y. Effects of Combined Electrical Stimulation of the Dorsal Column and Dorsal Roots on Wide-Dynamic-Range Neuronal Activity in Nerve-Injured Rats. Neuromodulation : Journal of the International Neuromodulation Society. PMID 26307526 DOI: 10.1111/Ner.12341  0.319
2015 Sdrulla AD, Xu Q, He SQ, Tiwari V, Yang F, Zhang C, Shu B, Shechter R, Raja SN, Wang Y, Dong X, Guan Y. Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice. Pain. 156: 1008-17. PMID 25974163 DOI: 10.1097/01.J.Pain.0000460353.15460.A3  0.355
2015 Kamerman PR, Wadley AL, Davis KD, Hietaharju A, Jain P, Kopf A, Meyer AC, Raja SN, Rice AS, Smith BH, Treede RD, Wiffen PJ. World Health Organization essential medicines lists: where are the drugs to treat neuropathic pain? Pain. 156: 793-7. PMID 25894010 DOI: 10.1097/01.j.pain.0000460356.94374.a1  0.629
2015 Gewandter JS, Dworkin RH, Turk DC, Farrar JT, Fillingim RB, Gilron I, Markman JD, Oaklander AL, Polydefkis MJ, Raja SN, Robinson JP, Woolf CJ, Ziegler D, Ashburn MA, Burke LB, et al. Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations. Pain. 156: 1184-97. PMID 25887465 DOI: 10.1097/J.Pain.0000000000000191  0.468
2015 Campbell CM, Buenaver LF, Raja SN, Kiley KB, Swedberg LJ, Wacnik PW, Cohen SP, Erdek MA, Williams KA, Christo PJ. Dynamic Pain Phenotypes are Associated with Spinal Cord Stimulation-Induced Reduction in Pain: A Repeated Measures Observational Pilot Study. Pain Medicine (Malden, Mass.). 16: 1349-60. PMID 25800088 DOI: 10.1111/Pme.12732  0.474
2015 Smith SN, Paige C, Velazquez KT, Smith TP, Raja SN, Wilson SP, Sweitzer SM. Injury-specific promoters enhance herpes simplex virus-mediated gene therapy for treating neuropathic pain in rodents. The Journal of Pain : Official Journal of the American Pain Society. 16: 283-90. PMID 25576797 DOI: 10.1016/J.Jpain.2014.12.007  0.445
2015 Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpää M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, et al. Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. The Lancet. Neurology. 14: 162-73. PMID 25575710 DOI: 10.1016/S1474-4422(14)70251-0  0.46
2015 Yang F, Zhang C, Xu Q, Tiwari V, He SQ, Wang Y, Dong X, Vera-Portocarrero LP, Wacnik PW, Raja SN, Guan Y. Electrical stimulation of dorsal root entry zone attenuates wide-dynamic-range neuronal activity in rats. Neuromodulation : Journal of the International Neuromodulation Society. 18: 33-40; discussion 40. PMID 25308522 DOI: 10.1111/Ner.12249  0.409
2015 Xu Q, Yang F, Sdrulla A, Raja S, Dong X, Guan Y. (351) Electrophysiologic mechanisms of “pain gating” in the superficial dorsal horn by activation of low-threshold afferent fibers The Journal of Pain. 16: S63. DOI: 10.1016/J.Jpain.2015.01.269  0.303
2014 Manning DC, Alexander G, Arezzo JC, Cooper A, Harden RN, Oaklander AL, Raja SN, Rauck R, Schwartzman R. Lenalidomide for complex regional pain syndrome type 1: lack of efficacy in a phase II randomized study. The Journal of Pain : Official Journal of the American Pain Society. 15: 1366-76. PMID 25283471 DOI: 10.1016/j.jpain.2014.09.013  0.404
2014 Wong K, Phelan R, Kalso E, Galvin I, Goldstein D, Raja S, Gilron I. Antidepressant drugs for prevention of acute and chronic postsurgical pain: early evidence and recommended future directions. Anesthesiology. 121: 591-608. PMID 25222675 DOI: 10.1097/ALN.0000000000000307  0.317
2014 Gewandter JS, Dworkin RH, Turk DC, McDermott MP, Baron R, Gastonguay MR, Gilron I, Katz NP, Mehta C, Raja SN, Senn S, Taylor C, Cowan P, Desjardins P, Dimitrova R, et al. Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations. Pain. 155: 1683-95. PMID 24865794 DOI: 10.1016/J.Pain.2014.05.025  0.312
2014 Tiwari V, Guan Y, Raja SN. Modulating the delicate glial-neuronal interactions in neuropathic pain: promises and potential caveats. Neuroscience and Biobehavioral Reviews. 45: 19-27. PMID 24820245 DOI: 10.1016/J.Neubiorev.2014.05.002  0.487
2014 Li Z, He SQ, Xu Q, Yang F, Tiwari V, Liu Q, Tang Z, Han L, Chu YX, Wang Y, Hin N, Tsukamoto T, Slusher B, Guan X, Wei F, ... Raja SN, et al. Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice. Pain. 155: 1613-21. PMID 24813294 DOI: 10.1016/J.Pain.2014.05.008  0.414
2014 Xu Q, Cheong YK, He SQ, Tiwari V, Liu J, Wang Y, Raja SN, Li J, Guan Y, Li W. Suppression of spinal connexin 43 expression attenuates mechanical hypersensitivity in rats after an L5 spinal nerve injury. Neuroscience Letters. 566: 194-9. PMID 24631560 DOI: 10.1016/J.Neulet.2014.03.004  0.384
2014 Xu Q, Cheong YK, Yang F, Tiwari V, Li J, Liu J, Raja SN, Li W, Guan Y. Intrathecal carbenoxolone inhibits neuropathic pain and spinal wide-dynamic range neuronal activity in rats after an L5 spinal nerve injury. Neuroscience Letters. 563: 45-50. PMID 24486838 DOI: 10.1016/J.Neulet.2014.01.042  0.427
2014 Yang F, Xu Q, Cheong YK, Shechter R, Sdrulla A, He SQ, Tiwari V, Dong X, Wacnik PW, Meyer R, Raja SN, Guan Y. Comparison of intensity-dependent inhibition of spinal wide-dynamic range neurons by dorsal column and peripheral nerve stimulation in a rat model of neuropathic pain. European Journal of Pain (London, England). 18: 978-88. PMID 24390782 DOI: 10.1002/J.1532-2149.2013.00443.X  0.623
2014 Xu JT, Zhao JY, Zhao X, Ligons D, Tiwari V, Atianjoh FE, Lee CY, Liang L, Zang W, Njoku D, Raja SN, Yaster M, Tao YX. Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia. The Journal of Clinical Investigation. 124: 592-603. PMID 24382350 DOI: 10.1172/Jci70236  0.399
2014 He SQ, Han L, Li Z, Xu Q, Tiwari V, Yang F, Guan X, Wang Y, Raja SN, Dong X, Guan Y. Temporal changes in MrgC expression after spinal nerve injury. Neuroscience. 261: 43-51. PMID 24374082 DOI: 10.1016/J.Neuroscience.2013.12.041  0.417
2014 He SQ, Li Z, Chu YX, Han L, Xu Q, Li M, Yang F, Liu Q, Tang Z, Wang Y, Hin N, Tsukamoto T, Slusher B, Tiwari V, Shechter R, ... ... Raja SN, et al. MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain. Pain. 155: 534-44. PMID 24333779 DOI: 10.1016/J.Pain.2013.12.008  0.515
2013 O'Connor AB, Turk DC, Dworkin RH, Katz NP, Colucci R, Haythornthwaite JA, Klein M, O'Brien C, Posner K, Rappaport BA, Reisfield G, Adams EH, Balster RL, Bigelow GE, Burke LB, ... ... Raja SN, et al. Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations. Pain. 154: 2324-34. PMID 24148704 DOI: 10.1016/J.Pain.2013.06.035  0.319
2013 Shechter R, Yang F, Xu Q, Cheong YK, He SQ, Sdrulla A, Carteret AF, Wacnik PW, Dong X, Meyer RA, Raja SN, Guan Y. Conventional and kilohertz-frequency spinal cord stimulation produces intensity- and frequency-dependent inhibition of mechanical hypersensitivity in a rat model of neuropathic pain. Anesthesiology. 119: 422-32. PMID 23880991 DOI: 10.1097/Aln.0B013E31829Bd9E2  0.562
2013 He SQ, Yang F, Perez FM, Xu Q, Shechter R, Cheong YK, Carteret AF, Dong X, Sweitzer SM, Raja SN, Guan Y. Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats. Pain. 154: 2477-86. PMID 23880055 DOI: 10.1016/J.Pain.2013.07.023  0.418
2013 Dworkin RH, O'Connor AB, Kent J, Mackey SC, Raja SN, Stacey BR, Levy RM, Backonja M, Baron R, Harke H, Loeser JD, Treede RD, Turk DC, Wells CD. Interventional management of neuropathic pain: NeuPSIG recommendations. Pain. 154: 2249-61. PMID 23748119 DOI: 10.1016/J.Pain.2013.06.004  0.465
2013 Cohen SP, Raja SN. Prevention of chronic postsurgical pain: the ongoing search for the holy grail of anesthesiology. Anesthesiology. 118: 241-3. PMID 23340346 DOI: 10.1097/ALN.0b013e31827d4129  0.465
2013 Finnerup NB, Scholz J, Attal N, Baron R, Haanpää M, Hansson P, Raja SN, Rice AS, Rief W, Rowbotham MC, Simpson DM, Treede RD. Neuropathic pain needs systematic classification. European Journal of Pain (London, England). 17: 953-6. PMID 23339030 DOI: 10.1002/J.1532-2149.2012.00282.X  0.483
2012 Comer SD, Zacny JP, Dworkin RH, Turk DC, Bigelow GE, Foltin RW, Jasinski DR, Sellers EM, Adams EH, Balster R, Burke LB, Cerny I, Colucci RD, Cone E, Cowan P, ... ... Raja SN, et al. Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations. Pain. 153: 2315-24. PMID 22998781 DOI: 10.1016/J.Pain.2012.07.035  0.31
2012 Ringkamp M, Tal M, Hartke TV, Wooten M, McKelvy A, Turnquist BP, Guan Y, Meyer RA, Raja SN. Local loperamide injection reduces mechanosensitivity of rat cutaneous, nociceptive C-fibers. Plos One. 7: e42105. PMID 22848720 DOI: 10.1371/Journal.Pone.0042105  0.624
2012 Turk DC, O'Connor AB, Dworkin RH, Chaudhry A, Katz NP, Adams EH, Brownstein JS, Comer SD, Dart R, Dasgupta N, Denisco RA, Klein M, Leiderman DB, Lubran R, Rappaport BA, ... ... Raja SN, et al. Research design considerations for clinical studies of abuse-deterrent opioid analgesics: IMMPACT recommendations. Pain. 153: 1997-2008. PMID 22770841 DOI: 10.1016/J.Pain.2012.05.029  0.325
2012 Chung C, Carteret AF, McKelvy AD, Ringkamp M, Yang F, Hartke TV, Dong X, Raja SN, Guan Y. Analgesic properties of loperamide differ following systemic and local administration to rats after spinal nerve injury. European Journal of Pain (London, England). 16: 1021-32. PMID 22508374 DOI: 10.1002/J.1532-2149.2012.00148.X  0.364
2012 Dworkin RH, Turk DC, Peirce-Sandner S, Burke LB, Farrar JT, Gilron I, Jensen MP, Katz NP, Raja SN, Rappaport BA, Rowbotham MC, Backonja MM, Baron R, Bellamy N, Bhagwagar Z, et al. Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations. Pain. 153: 1148-58. PMID 22494920 DOI: 10.1016/J.Pain.2012.03.003  0.376
2012 Raja SN. Modulating pain in the periphery: gene-based therapies to enhance peripheral opioid analgesia: Bonica lecture, ASRA 2010. Regional Anesthesia and Pain Medicine. 37: 210-4. PMID 22189620 DOI: 10.1097/AAP.0b013e31823b145f  0.504
2011 McGreevy K, Bottros MM, Raja SN. Preventing Chronic Pain following Acute Pain: Risk Factors, Preventive Strategies, and their Efficacy. European Journal of Pain Supplements. 5: 365-372. PMID 22102847 DOI: 10.1016/j.eujps.2011.08.013  0.485
2011 Yang F, Carteret AF, Wacnik PW, Chung CY, Xing L, Dong X, Meyer RA, Raja SN, Guan Y. Bipolar spinal cord stimulation attenuates mechanical hypersensitivity at an intensity that activates a small portion of A-fiber afferents in spinal nerve-injured rats. Neuroscience. 199: 470-80. PMID 22001681 DOI: 10.1016/J.Neuroscience.2011.09.049  0.571
2011 Yang F, Chung CY, Wacnik PW, Carteret AF, McKelvy AD, Meyer RA, Raja SN, Guan Y. Electrical stimulation at distinct peripheral sites in spinal nerve injured rats leads to different afferent activation profiles. Neuroscience Letters. 505: 52-7. PMID 22001268 DOI: 10.1016/J.Neulet.2011.09.065  0.543
2011 Park U, Vastani N, Guan Y, Raja SN, Koltzenburg M, Caterina MJ. TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11425-36. PMID 21832173 DOI: 10.1523/Jneurosci.1384-09.2011  0.333
2011 Donello JE, Guan Y, Tian M, Cheevers CV, Alcantara M, Cabrera S, Raja SN, Gil DW. A peripheral adrenoceptor-mediated sympathetic mechanism can transform stress-induced analgesia into hyperalgesia. Anesthesiology. 114: 1403-16. PMID 21540738 DOI: 10.1097/Aln.0B013E31821C3878  0.441
2011 Cohen SP, Gambel JM, Raja SN, Galvagno S. The contribution of sympathetic mechanisms to postamputation phantom and residual limb pain: a pilot study. The Journal of Pain : Official Journal of the American Pain Society. 12: 859-67. PMID 21481650 DOI: 10.1016/J.Jpain.2011.01.009  0.483
2011 Attal N, Bouhassira D, Baron R, Dostrovsky J, Dworkin RH, Finnerup N, Gourlay G, Haanpaa M, Raja S, Rice AS, Simpson D, Treede RD. Assessing symptom profiles in neuropathic pain clinical trials: can it improve outcome? European Journal of Pain (London, England). 15: 441-3. PMID 21458336 DOI: 10.1016/j.ejpain.2011.03.005  0.588
2011 Dworkin RH, Turk DC, Basch E, Berger A, Cleeland C, Farrar JT, Haythornthwaite JA, Jensen MP, Kerns RD, Markman J, Porter L, Raja SN, Ross E, Todd K, Wallace M, et al. Considerations for extrapolating evidence of acute and chronic pain analgesic efficacy. Pain. 152: 1705-8. PMID 21396781 DOI: 10.1016/J.Pain.2011.02.026  0.457
2011 Lee CY, Perez FM, Wang W, Guan X, Zhao X, Fisher JL, Guan Y, Sweitzer SM, Raja SN, Tao YX. Dynamic temporal and spatial regulation of mu opioid receptor expression in primary afferent neurons following spinal nerve injury. European Journal of Pain (London, England). 15: 669-75. PMID 21310637 DOI: 10.1016/J.Ejpain.2010.11.018  0.439
2011 Goff BJ, Castillo R, Raja SN. Painful sequelae following limb salvage: etiology and management. The Journal of the American Academy of Orthopaedic Surgeons. 19: S23-7. PMID 21304043 DOI: 10.5435/00124635-201102001-00005  0.477
2011 Lee FH, Raja SN. Complementary and alternative medicine in chronic pain. Pain. 152: 28-30. PMID 20933330 DOI: 10.1016/j.pain.2010.09.023  0.469
2011 Wacnik P, Yang F, Chung C, Meyer R, Raja S, Guan Y. S704 PROPORTION OF MYELINATED FIBERS ACTIVATED BY VARIOUS PERIPHERAL TISSUE/NERVE ELECTRICAL STIMULATION THERAPIES DIFFER IN SPINAL NERVE-INJURED RATS European Journal of Pain Supplements. 5: 286-287. DOI: 10.1016/S1754-3207(11)70988-9  0.524
2011 Bartels K, Cohen SP, Raja SN. Postamputation pain Essentials of Pain Medicine. 365-369. DOI: 10.1016/B978-1-4377-2242-0.00061-4  0.394
2011 Dougherty PM, Raja SN, Boyette-Davis J. Neurochemistry of somatosensory and pain processing Essentials of Pain Medicine. 8-15. DOI: 10.1016/B978-1-4377-2242-0.00011-0  0.371
2011 Raja SN, Dougherty PM. Anatomy and physiology of somatosensory and pain processing Essentials of Pain Medicine. 1-7. DOI: 10.1016/B978-1-4377-2242-0.00010-9  0.374
2011 Benzon H, Fishman S, Liu S, Cohen SP, Raja SN. Essentials of Pain Medicine Essentials of Pain Medicine 0.391
2010 Guan Y, Wacnik PW, Yang F, Carteret AF, Chung CY, Meyer RA, Raja SN. Spinal cord stimulation-induced analgesia: electrical stimulation of dorsal column and dorsal roots attenuates dorsal horn neuronal excitability in neuropathic rats. Anesthesiology. 113: 1392-405. PMID 21068658 DOI: 10.1097/Aln.0B013E3181Fcd95C  0.555
2010 Guan Y, Liu Q, Tang Z, Raja SN, Anderson DJ, Dong X. Mas-related G-protein-coupled receptors inhibit pathological pain in mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 15933-8. PMID 20724664 DOI: 10.1073/Pnas.1011221107  0.493
2010 Borzan J, Zhao C, Meyer RA, Raja SN. A role for acid-sensing ion channel 3, but not acid-sensing ion channel 2, in sensing dynamic mechanical stimuli. Anesthesiology. 113: 647-54. PMID 20693874 DOI: 10.1097/ALN.0b013e3181eaa58a  0.537
2010 Raja SN, Jensen TS. Predicting postoperative pain based on preoperative pain perception: are we doing better than the weatherman? Anesthesiology. 112: 1311-2. PMID 20502114 DOI: 10.1097/ALN.0b013e3181dcd5cc  0.51
2010 Guan Y, Raja SN. Wide-dynamic-range neurons are heterogeneous in windup responsiveness to changes in stimulus intensity and isoflurane anesthesia level in mice. Journal of Neuroscience Research. 88: 2272-83. PMID 20209628 DOI: 10.1002/Jnr.22383  0.323
2010 Dworkin RH, Turk DC, Peirce-Sandner S, McDermott MP, Farrar JT, Hertz S, Katz NP, Raja SN, Rappaport BA. Placebo and treatment group responses in postherpetic neuralgia vs. painful diabetic peripheral neuropathy clinical trials in the REPORT database. Pain. 150: 12-6. PMID 20202753 DOI: 10.1016/J.Pain.2010.02.002  0.391
2010 Dworkin RH, O'Connor AB, Audette J, Baron R, Gourlay GK, Haanpää ML, Kent JL, Krane EJ, Lebel AA, Levy RM, Mackey SC, Mayer J, Miaskowski C, Raja SN, Rice AS, et al. Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. Mayo Clinic Proceedings. 85: S3-14. PMID 20194146 DOI: 10.4065/Mcp.2009.0649  0.362
2010 Haanpää ML, Gourlay GK, Kent JL, Miaskowski C, Raja SN, Schmader KE, Wells CD. Treatment considerations for patients with neuropathic pain and other medical comorbidities. Mayo Clinic Proceedings. 85: S15-25. PMID 20194144 DOI: 10.4065/Mcp.2009.0645  0.386
2010 Dworkin RH, McDermott MP, Raja SN. Preventing chronic postsurgical pain: how much of a difference makes a difference? Anesthesiology. 112: 516-8. PMID 20124976 DOI: 10.1097/Aln.0B013E3181Cf4253  0.463
2010 Guan Y, Yuan F, Carteret AF, Raja SN. A partial L5 spinal nerve ligation induces a limited prolongation of mechanical allodynia in rats: an efficient model for studying mechanisms of neuropathic pain. Neuroscience Letters. 471: 43-7. PMID 20067820 DOI: 10.1016/J.Neulet.2010.01.006  0.52
2010 Borzan J, Tall JM, Zhao C, Meyer RA, Raja SN. Effects of soy diet on inflammation-induced primary and secondary hyperalgesia in rat. European Journal of Pain (London, England). 14: 792-8. PMID 20060762 DOI: 10.1016/j.ejpain.2009.12.002  0.524
2010 Guan Y, Carteret A, Wacnik P, Meyer R, Raja S. 517 BI-POLAR SPINAL CORD STIMULATION ATTENUATED MECHANICAL ALLODYNIA IN NEUROPATHIC RATS AT INTENSITIES THAT ACTIVATES A SMALL FRACTION OF A-FIBER AFFERENTS European Journal of Pain Supplements. 4: 146-146. DOI: 10.1016/S1754-3207(10)70522-8  0.514
2010 Bounds S, Klick B, Buenaver L, Smith M, Edwards R, Grace E, Raja S, Haythornthwaite J. Recruitment and retention in pain studies: experience from a clinical trial involving behavioral and pharmacological therapies The Journal of Pain. 11: S40. DOI: 10.1016/J.Jpain.2010.01.168  0.399
2010 Guan Y, Wacnik P, Carteret A, Meyer R, Raja S. A model combining in vivo electrophysiological and behavioral approaches to study mechanisms of spinal cord stimulation induced analgesia in spinal nerve injured rats The Journal of Pain. 11: S28. DOI: 10.1016/J.Jpain.2010.01.120  0.515
2010 Sweitzer SM, Minella CE, Wilson SP, Raja SN. Peripheral opioid analgesia for the treatment of neuropathic pain: Gene mutation to virus mediated gene transfer European Journal of Pain Supplements. 4: 251-256. DOI: 10.1016/J.Eujps.2010.09.013  0.507
2010 Sharma A, Campbell JN, Raja SN. Sympathetic Blocks for Pain The Senses: a Comprehensive Reference. 5: 227-235. DOI: 10.1016/B978-012370880-9.00159-6  0.593
2009 Seal RP, Wang X, Guan Y, Raja SN, Woodbury CJ, Basbaum AI, Edwards RH. Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors. Nature. 462: 651-5. PMID 19915548 DOI: 10.1038/Nature08505  0.34
2009 Sharma A, Agarwal S, Broatch J, Raja SN. A web-based cross-sectional epidemiological survey of complex regional pain syndrome. Regional Anesthesia and Pain Medicine. 34: 110-5. PMID 19282709 DOI: 10.1097/Aap.0B013E3181958F90  0.388
2009 Singh OV, Yaster M, Xu JT, Guan Y, Guan X, Dharmarajan AM, Raja SN, Zeitlin PL, Tao YX. Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury. Proteomics. 9: 1241-53. PMID 19206110 DOI: 10.1002/Pmic.200800636  0.369
2009 Cohen SP, Raja SN. Does prolonged skin temperature measurement improve the diagnosis of complex regional pain syndrome? Nature Clinical Practice. Neurology. 5: 14-5. PMID 19129786 DOI: 10.1038/ncpneuro0987  0.442
2008 Park JS, Yaster M, Guan X, Xu JT, Shih MH, Guan Y, Raja SN, Tao YX. Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory pain. Molecular Pain. 4: 67. PMID 19116032 DOI: 10.1186/1744-8069-4-67  0.409
2008 Wu CL, Agarwal S, Tella PK, Klick B, Clark MR, Haythornthwaite JA, Max MB, Raja SN. Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trial. Anesthesiology. 109: 289-96. PMID 18648238 DOI: 10.1097/ALN.0b013e31817f4523  0.466
2008 Guan Y, Johanek LM, Hartke TV, Shim B, Tao YX, Ringkamp M, Meyer RA, Raja SN. Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury. Pain. 138: 318-29. PMID 18276075 DOI: 10.1016/J.Pain.2008.01.004  0.618
2008 Zhang G, Mohammad H, Peper BD, Raja S, Wilson SP, Sweitzer SM. Enhanced peripheral analgesia using virally mediated gene transfer of the mu-opioid receptor in mice. Anesthesiology. 108: 305-13. PMID 18212576 DOI: 10.1097/01.Anes.0000299836.61785.79  0.385
2008 Dworkin RH, Gnann JW, Oaklander AL, Raja SN, Schmader KE, Whitley RJ. Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia. The Journal of Pain : Official Journal of the American Pain Society. 9: S37-44. PMID 18166464 DOI: 10.1016/j.jpain.2007.10.008  0.486
2008 Chu YC, Guan Y, Skinner J, Raja SN, Johns RA, Tao YX. Corrigendum to "Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain" [Pain 119 (2005) 113-123] (DOI:10.1016/j.pain.2005.09.024) Pain. 137: 463. DOI: 10.1016/J.Pain.2008.04.011  0.482
2008 Haythornthwaite J, Edwards R, Buenaver L, Campbell C, Raja S. (321) The effects of opioids and tricyclic antidepressants on pain-related catastrophizing in patients with postherpetic neuralgia The Journal of Pain. 9: 56. DOI: 10.1016/J.Jpain.2008.01.244  0.453
2008 Singh O, Yaster M, Guan Y, Raja S, Zeitlin P, Tao Y. (104) Peripheral nerve injury insult alters proteomic profile of the spinal dorsal horn synaptosome-associated proteins The Journal of Pain. 9: 2. DOI: 10.1016/J.Jpain.2008.01.022  0.321
2007 Guan Y, Yaster M, Raja SN, Tao YX. Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice. Molecular Pain. 3: 29. PMID 17922909 DOI: 10.1186/1744-8069-3-29  0.402
2007 Agarwal S, Polydefkis M, Block B, Haythornthwaite J, Raja SN. Transdermal fentanyl reduces pain and improves functional activity in neuropathic pain states. Pain Medicine (Malden, Mass.). 8: 554-62. PMID 17883740 DOI: 10.1111/j.1526-4637.2006.00246.x  0.493
2007 Zhao C, Chen L, Tao YX, Tall JM, Borzan J, Ringkamp M, Meyer RA, Raja SN. Lumbar sympathectomy attenuates cold allodynia but not mechanical allodynia and hyperalgesia in rats with spared nerve injury. The Journal of Pain : Official Journal of the American Pain Society. 8: 931-7. PMID 17693138 DOI: 10.1016/J.Jpain.2007.06.008  0.637
2007 Kudel I, Edwards RR, Kozachik S, Block BM, Agarwal S, Heinberg LJ, Haythornthwaite J, Raja SN. Predictors and consequences of multiple persistent postmastectomy pains. Journal of Pain and Symptom Management. 34: 619-27. PMID 17629668 DOI: 10.1016/J.Jpainsymman.2007.01.013  0.488
2007 Cohen SP, Raja SN. Pathogenesis, diagnosis, and treatment of lumbar zygapophysial (facet) joint pain. Anesthesiology. 106: 591-614. PMID 17325518 DOI: 10.1097/00000542-200703000-00024  0.355
2007 Guan Y, Johanek L, Hartke T, Shim B, Chen D, Ringkamp M, Meyer R, Raja S. (759) The Journal of Pain. 8: S40. DOI: 10.1016/J.Jpain.2007.02.164  0.477
2006 Cohen SP, Raja SN. The middle way: a practical approach to prescribing opioids for chronic pain. Nature Clinical Practice. Neurology. 2: 580-1. PMID 17057740 DOI: 10.1038/ncpneuro0342  0.414
2006 Sharma A, Williams K, Raja SN. Advances in treatment of complex regional pain syndrome: recent insights on a perplexing disease. Current Opinion in Anaesthesiology. 19: 566-72. PMID 16960493 DOI: 10.1097/01.Aco.0000245286.30282.Ab  0.382
2006 Lin EE, Horasek S, Agarwal S, Wu CL, Raja SN. Local administration of norepinephrine in the stump evokes dose-dependent pain in amputees. The Clinical Journal of Pain. 22: 482-6. PMID 16772803 DOI: 10.1097/01.ajp.0000202980.51786.ae  0.51
2006 Edwards RR, Haythornthwaite JA, Tella P, Max MB, Raja S. Basal heat pain thresholds predict opioid analgesia in patients with postherpetic neuralgia. Anesthesiology. 104: 1243-8. PMID 16732096 DOI: 10.1097/00000542-200606000-00020  0.493
2006 Guan Y, Borzan J, Meyer RA, Raja SN. Windup in dorsal horn neurons is modulated by endogenous spinal mu-opioid mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4298-307. PMID 16624950 DOI: 10.1523/Jneurosci.0960-06.2006  0.526
2006 Edwards RR, Raja S. The laterality of long-term pain following mastectomy. Journal of Pain and Symptom Management. 31: 98-9. PMID 16488342 DOI: 10.1016/J.Jpainsymman.2005.12.002  0.425
2006 Raja SN, Brennan TJ. Special issue on plasticity in postoperative pain: Select reports from the Journal-sponsored symposium Anesthesiology. 104: 397-398. DOI: 10.1097/00000542-200603000-00002  0.44
2005 Chu YC, Guan Y, Skinner J, Raja SN, Johns RA, Tao YX. Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain. Pain. 119: 113-23. PMID 16297560 DOI: 10.1016/J.Pain.2005.09.024  0.494
2005 Meyer RA, Ringkamp M, Campbell JN, Raja SN. Neural mechanisms of hyperalgesia after tissue injury Johns Hopkins Apl Technical Digest (Applied Physics Laboratory). 26: 56-66.  0.546
2004 Tall JM, Seeram NP, Zhao C, Nair MG, Meyer RA, Raja SN. Tart cherry anthocyanins suppress inflammation-induced pain behavior in rat. Behavioural Brain Research. 153: 181-8. PMID 15219719 DOI: 10.1016/J.Bbr.2003.11.011  0.605
2004 Zhao C, Tall JM, Meyer RA, Raja SN. Antiallodynic effects of systemic and intrathecal morphine in the spared nerve injury model of neuropathic pain in rats. Anesthesiology. 100: 905-11. PMID 15087626 DOI: 10.1097/00000542-200404000-00021  0.61
2004 Zhao C, Wacnik PW, Tall JM, Johns DC, Wilcox GL, Meyer RA, Raja SN. Analgesic effects of a soy-containing diet in three murine bone cancer pain models. The Journal of Pain : Official Journal of the American Pain Society. 5: 104-10. PMID 15042518 DOI: 10.1016/J.Jpain.2003.12.001  0.57
2004 Tall JM, Raja SN. Dietary constituents as novel therapies for pain. The Clinical Journal of Pain. 20: 19-26. PMID 14668652 DOI: 10.1097/00002508-200401000-00005  0.426
2003 Zhao CS, Tao YX, Tall JM, Donovan DM, Meyer RA, Raja SN. Role of micro-opioid receptors in formalin-induced pain behavior in mice. Experimental Neurology. 184: 839-45. PMID 14769376 DOI: 10.1016/S0014-4886(03)00346-7  0.567
2002 Mansikka H, Zhou L, Donovan DM, Pertovaara A, Raja SN. The role of mu-opioid receptors in inflammatory hyperalgesia and alpha 2-adrenoceptor-mediated antihyperalgesia. Neuroscience. 113: 339-49. PMID 12127091 DOI: 10.1016/S0306-4522(02)00189-6  0.348
2002 Shir Y, Campbell JN, Raja SN, Seltzer Z. The correlation between dietary soy phytoestrogens and neuropathic pain behavior in rats after partial denervation. Anesthesia and Analgesia. 94: 421-6, table of cont. PMID 11812712 DOI: 10.1213/00000539-200202000-00037  0.586
2001 Shir Y, Raja SN, Weissman CS, Campbell JN, Seltzer Z. Consumption of soy diet before nerve injury preempts the development of neuropathic pain in rats. Anesthesiology. 95: 1238-44. PMID 11684996 DOI: 10.1097/00000542-200111000-00031  0.565
2001 Shir Y, Sheth R, Campbell JN, Raja SN, Seltzer Z. Soy-containing diet suppresses chronic neuropathic sensory disorders in rats. Anesthesia and Analgesia. 92: 1029-34. PMID 11273945 DOI: 10.1097/00000539-200104000-00042  0.574
2001 Fuchs PN, Meyer RA, Raja SN. Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin. Pain. 90: 15-23. PMID 11166966 DOI: 10.1016/S0304-3959(00)00381-X  0.606
2000 Raja SN, Campbell JN. Risk-benefit ratio for surgical sympathectomy: dilemmas in clinical decision making. The Journal of Pain : Official Journal of the American Pain Society. 1: 261-4. PMID 14622607 DOI: 10.1054/jpai.2000.14261  0.414
2000 Ali Z, Raja SN, Wesselmann U, Fuchs PN, Meyer RA, Campbell JN. Intradermal injection of norepinephrine evokes pain in patients with sympathetically maintained pain. Pain. 88: 161-8. PMID 11050371 DOI: 10.1016/S0304-3959(00)00327-4  0.722
2000 Tran KM, Frank SM, Raja SN, El-Rahmany HK, Kim LJ, Vu B. Lumbar sympathetic block for sympathetically maintained pain: changes in cutaneous temperatures and pain perception. Anesthesia and Analgesia. 90: 1396-401. PMID 10825327 DOI: 10.1097/00000539-200006000-00025  0.434
2000 Mansikka H, Sheth RN, DeVries C, Lee H, Winchurch R, Raja SN. Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice. Experimental Neurology. 162: 343-9. PMID 10739640 DOI: 10.1006/exnr.1999.7336  0.438
2000 Todd M, Raja SN, Eisenach JC. International Association for the Study of Pain 9th World Congress on Pain. Anesthesiology. 92: 292-292. DOI: 10.1097/00000542-200001000-00061  0.481
1999 Ringkamp M, Eschenfelder S, Grethel EJ, Häbler HJ, Meyer RA, Jänig W, Raja SN. Lumbar sympathectomy failed to reverse mechanical allodynia- and hyperalgesia-like behavior in rats with L5 spinal nerve injury. Pain. 79: 143-53. PMID 10068160 DOI: 10.1016/S0304-3959(98)00186-9  0.555
1999 Ringkamp M, Grethel EJ, Choi Y, Meyer RA, Raja SN. Mechanical hyperalgesia after spinal nerve ligation in rat is not reversed by intraplantar or systemic administration of adrenergic antagonists. Pain. 79: 135-41. PMID 10068159 DOI: 10.1016/S0304-3959(98)00185-7  0.579
1999 Fuchs PN, Roza C, Sora I, Uhl G, Raja SN. Characterization of mechanical withdrawal responses and effects of mu-, delta- and kappa-opioid agonists in normal and mu-opioid receptor knockout mice. Brain Research. 821: 480-6. PMID 10064835 DOI: 10.1016/S0006-8993(99)01060-4  0.303
1999 Fuchs PN, Ringkamp M, Shiotani M, Raja SN. Sympathectomy decreases formalin-induced nociceptive responses independent of changes in peripheral blood flow. Experimental Neurology. 155: 95-102. PMID 9918708 DOI: 10.1006/Exnr.1998.6967  0.356
1998 Shir Y, Ratner A, Raja SN, Campbell JN, Seltzer Z. Neuropathic pain following partial nerve injury in rats is suppressed by dietary soy. Neuroscience Letters. 240: 73-6. PMID 9486475 DOI: 10.1016/S0304-3940(97)00923-3  0.574
1998 Raja SN. Peripheral modulatory effects of catecholamines in inflammatory and neuropathic pain. Advances in Pharmacology (San Diego, Calif.). 42: 567-71. PMID 9327965 DOI: 10.1016/S1054-3589(08)60814-5  0.508
1997 Raja SN. Nerve blocks in the evaluation of chronic pain. Anesthesiology. 86: 4-6. PMID 9009933 DOI: 10.1097/00000542-199701000-00001  0.481
1996 Raja SN, Turnquist JL, Meleka S, Campbell JN. Monitoring adequacy of alpha-adrenoceptor blockade following systemic phentolamine administration. Pain. 64: 197-204. PMID 8867263 DOI: 10.1016/0304-3959(95)00099-2  0.502
1996 Lam HH, Hanley DF, Trapp BD, Saito S, Raja S, Dawson TM, Yamaguchi H. Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw. Neuroscience Letters. 210: 201-4. PMID 8805130 DOI: 10.1016/0304-3940(96)12702-6  0.308
1996 Choi Y, Raja SN, Moore LC, Tobin JR. Neuropathic pain in rats is associated with altered nitric oxide synthase activity in neural tissue. Journal of the Neurological Sciences. 138: 14-20. PMID 8791233 DOI: 10.1016/0022-510X(95)00325-V  0.444
1995 Campbell JN, Raja SN. Reflex sympathetic dystrophy. Neurology. 45: 1235-7. PMID 7783904 DOI: 10.1212/Wnl.45.6.1235-A  0.48
1995 Treede RD, Meyer RA, Raja SN, Campbell JN. Evidence for two different heat transduction mechanisms in nociceptive primary afferents innervating monkey skin. The Journal of Physiology. 483: 747-58. PMID 7776255 DOI: 10.1113/Jphysiol.1995.Sp020619  0.61
1995 Raja SN. Role of the sympathetic nervous system in acute pain and inflammation. Annals of Medicine. 27: 241-6. PMID 7632421 DOI: 10.3109/07853899509031966  0.496
1994 Pappagallo M, Raja SN, Haythornthwaite JA, Clarke M, Campbell JN. Oral Opioids in the Management of Postherpetic Neuralgia: A Prospective Survey Analgesia. 1: 51-55. DOI: 10.3727/107156994819564438  0.377
1993 Shir Y, Cameron LB, Raja SN, Bourke DL. The safety of intravenous phentolamine administration in patients with neuropathic pain. Anesthesia and Analgesia. 76: 1008-11. PMID 8484498 DOI: 10.1213/00000539-199305000-00016  0.391
1993 Raja SN, Meyer RA, Campbell JN. Clonidine: effects on pre- vs. post-junctional adrenoceptors. Pain. 54: 361-2. PMID 8233554 DOI: 10.1016/0304-3959(93)90039-R  0.564
1992 Treede RD, Davis KD, Campbell JN, Raja SN. The plasticity of cutaneous hyperalgesia during sympathetic ganglion blockade in patients with neuropathic pain. Brain : a Journal of Neurology. 115: 607-21. PMID 1606484 DOI: 10.1093/Brain/115.2.607  0.725
1992 Treede RD, Meyer RA, Raja SN, Campbell JN. Peripheral and central mechanisms of cutaneous hyperalgesia. Progress in Neurobiology. 38: 397-421. PMID 1574584 DOI: 10.1016/0301-0082(92)90027-C  0.685
1992 Meyer RA, Davis KD, Raja SN, Campbell JN. Sympathectomy does not abolish bradykinin-induced cutaneous hyperalgesia in man. Pain. 51: 323-7. PMID 1491860 DOI: 10.1016/0304-3959(92)90217-Y  0.744
1992 Raja SN, Dickstein RE, Johnson CA. Comparison of postoperative analgesic effects of intraarticular bupivacaine and morphine following arthroscopic knee surgery. Anesthesiology. 77: 1143-7. PMID 1466465 DOI: 10.1097/00000542-199212000-00015  0.316
1992 Raja SN, Davis KD, Campbell JN. The adrenergic pharmacology of sympathetically-maintained pain. Journal of Reconstructive Microsurgery. 8: 63-9. PMID 1349919 DOI: 10.1055/s-2007-1006686  0.719
1992 Raja SN, Campbell JN, Meyer RA, Colman RW. Role of kinins in pain and hyperalgesia: psychophysical studies in a patient with kininogen deficiency. Clinical Science (London, England : 1979). 83: 337-41. PMID 1327652 DOI: 10.1042/Cs0830337  0.716
1992 Khan AA, Raja SN, Manning DC, Campbell JN, Meyer RA. The effects of bradykinin and sequence-related analogs on the response properties of cutaneous nociceptors in monkeys. Somatosensory & Motor Research. 9: 97-106. PMID 1323902 DOI: 10.3109/08990229209144765  0.633
1992 Campbell JN, Meyer RA, Raja SN. Is nociceptor activation by alpha-1 adrenoreceptors the culprit in sympathetically maintained pain? Aps Journal. 1: 3-11. DOI: 10.1016/S1058-9139(06)80003-3  0.678
1992 Meyer RA, Treede RD, Raja SN, Campbell JN. Peripheral versus central mechanisms for secondary hyperalgesia Is the Controversy Resolved? Aps Journal. 1: 127-131. DOI: 10.1016/1058-9139(92)90041-A  0.623
1991 Raja SN, Treede RD, Davis KD, Campbell JN. Systemic alpha-adrenergic blockade with phentolamine: a diagnostic test for sympathetically maintained pain. Anesthesiology. 74: 691-8. PMID 1848966 DOI: 10.1097/00000542-199104000-00012  0.716
1991 Manning DC, Raja SN, Meyer RA, Campbell JN. Pain and hyperalgesia after intradermal injection of bradykinin in humans. Clinical Pharmacology and Therapeutics. 50: 721-9. PMID 1752117 DOI: 10.1038/Clpt.1991.212  0.722
1991 Davis KD, Treede RD, Raja SN, Meyer RA, Campbell JN. Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain. Pain. 47: 309-17. PMID 1664508 DOI: 10.1016/0304-3959(91)90221-I  0.737
1991 Davis KD, Raja SN, Treede RD, Meyer RA, Campbell JN. Topical Application of Clonidine Eliminates Hyperalgesia at Site of Administration in Patients with Sympathetically-Maintained Pain The Clinical Journal of Pain. 7: 57. DOI: 10.1097/00002508-199103000-00079  0.744
1991 Manning D, Raja S, Meyer R, Campbell J. INTRADERMAL BRADYKININ INDUCES PAIN AND HYPERALGESIA IN HUMANS Anesthesiology. 75: A699-A699. DOI: 10.1097/00000542-199109001-00698  0.701
1990 Treede R, Raja S, Davis K, Meyer R, Campbell J. Evidence that alpha-adrenergic receptors mediate sympathetically maintained pain (reflex sympathetic dystrophy) Pain. 41: S487. DOI: 10.1016/0304-3959(90)93085-C  0.734
1990 Davis K, Campbell J, Raja S, Treede R, Lin C, Meyer R. Topical application of an α2-adrenergic agonist relieves hyperalgesia in sympathetically-maintained pain: A case study Pain. 41: S421. DOI: 10.1016/0304-3959(90)92958-S  0.686
1990 Raja S, Kozak S, Manning D, Meyer R, Campbell J. Intradermal bradykinin induces hyperalgesia to heat stimuli in man Pain. 41: S130. DOI: 10.1016/0304-3959(90)92397-9  0.599
1989 Raja SN, Treede RD, Tewes PA, Davis KD, Lin C, Campbell JN. A NEW DIAGNOSTIC TEST FOR SYMPATHETICALLY MAINTAINED PAIN Anesthesiology. 71: A732. DOI: 10.1097/00000542-198909001-00732  0.685
1988 Campbell JN, Khan AA, Meyer RA, Raja SN. Responses to heat of C-fiber nociceptors in monkey are altered by injury in the receptive field but not by adjacent injury. Pain. 32: 327-32. PMID 3362567 DOI: 10.1016/0304-3959(88)90044-9  0.603
1988 Meyer RA, Campbell JN, Raja SN. Antidromic nerve stimulation in monkey does not sensitize unmyelinated nociceptors to heat. Brain Research. 441: 168-72. PMID 3359229 DOI: 10.1016/0006-8993(88)91395-9  0.621
1988 Campbell JN, Raja SN, Meyer RA, Mackinnon SE. Myelinated afferents signal the hyperalgesia associated with nerve injury. Pain. 32: 89-94. PMID 3340426 DOI: 10.1016/0304-3959(88)90027-9  0.66
1988 Raja SN, Meyer RA, Campbell JN. Peripheral mechanisms of somatic pain. Anesthesiology. 68: 571-90. PMID 3281512 DOI: 10.1097/00000542-198804000-00016  0.702
1987 Raja SN, Campbell JN, Meyer RA, Frost SA, Khan AA. Does hyperalgesia to cold stimuli characterize patients with sympathetically maintained pain (reflex sympathetic dystrophy)? Pain. 30: S344. DOI: 10.1016/0304-3959(87)91743-X  0.715
1987 Campbell JN, Raja SN, Meyer RA. Painful sequelae of nerve injury Pain. 30: S334. DOI: 10.1016/0304-3959(87)91728-3  0.697
1987 Mannin DC, Rhan AA, Campbell JN, Meyer RA, Raja SN. Bradykinin induced cutaneous pain is independent of wheal and flare Pain. 30: S16. DOI: 10.1016/0304-3959(87)91111-0  0.712
1986 Raja SN, Meyer RA, Campbell JN, Khan AA. Narcotics do not alter the heat response of unmyelinated primary afferents in monkeys. Anesthesiology. 65: 468-73. PMID 3777476 DOI: 10.1097/00000542-198611000-00003  0.664
1985 Meyer RA, Raja SN, Campbell JN. Coupling of action potential activity between unmyelinated fibers in the peripheral nerve of monkey. Science (New York, N.Y.). 227: 184-7. PMID 3966152 DOI: 10.1016/0304-3959(86)90132-6  0.607
1985 Meyer RA, Raja SN, Campbell JN, Mackinnon SE, Dellon AL. Neural activity originating from a neuroma in the baboon. Brain Research. 325: 255-60. PMID 2983828 DOI: 10.1016/0006-8993(85)90321-X  0.62
1984 Raja SN, Campbell JN, Meyer RA. Evidence for different mechanisms of primary and secondary hyperalgesia following heat injury to the glabrous skin. Brain : a Journal of Neurology. 107: 1179-88. PMID 6509313 DOI: 10.1093/brain/107.4.1179  0.671
1984 Campbell JN, Raja SN, Meyer RA. Halothane sensitizes cutaneous nociceptors in monkeys. Journal of Neurophysiology. 52: 762-70. PMID 6491715 DOI: 10.1152/Jn.1984.52.4.762  0.61
1984 Raja S, Campbell J, Meyer R, Mackinnon S. MYELINATED FIBERS IN PERIPHERAL NERVES SIGNAL THE HYPERALGESIA THAT FOLLOWS NERVE INJURY Anesthesiology. 61: A199-A199. DOI: 10.1097/00000542-198409001-00199  0.616
1984 Meyer RA, Campbell JN, Raja SN. Coupling of action potential activity between unmyelinated fibers in the normal peripheral nerve of sat 2:45 monkey Pain. 18: S8. DOI: 10.1016/0304-3959(84)90142-8  0.609
1984 Raja SN, Campbell JN, Meyer RA, Mackinnon SE. Hyperalgesia following peripheral nerve injury is signalled by myelinated fibers Pain. 18: S8. DOI: 10.1016/0304-3959(84)90141-6  0.614
1984 Campbell JN, Meyer RA, Raja SN. Hyperalgesia: New insights Pain. 18: S3. DOI: 10.1016/0304-3959(84)90135-0  0.573
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