Steven J. Harper - Publications

Affiliations: 
Department of Physiology University of Bristol, Bristol, England, United Kingdom 

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Crompton M, Ferguson JK, Ramnath R, Onions KL, Ogier AS, Gamez M, Down CJ, Skinner LJ, Wong KH, Dixon LK, Sutak J, Harper SJ, Pontrelli P, Gesualdo L, Heerspink HL, et al. Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx. Jci Insight. PMID 36749631 DOI: 10.1172/jci.insight.154164  0.78
2022 Finch N, Fawaz S, Neal C, Butler M, Lee V, Salmon A, Lay A, Stevens M, Dalayan L, Band H, Mellor H, Harper S, Shima D, Welsh G, Foster R, et al. Reduced Glomerular Filtration in Diabetes is Attributable to Loss of Density and Increased Resistance of Glomerular Endothelial Cell Fenestrations. Journal of the American Society of Nephrology : Jasn. PMID 35292439 DOI: 10.1681/ASN.2021030294  0.6
2019 Stevens M, Star E, Lee M, Innes E, Li L, Bowler E, Harper S, Bates DO, Oltean S. The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds . Rna Biology. 1-10. PMID 31432737 DOI: 10.1080/15476286.2019.1652522  0.724
2019 Stevens M, Neal CR, Craciun EC, Dronca M, Harper SJ, Oltean S. The natural drug DIAVIT is protective in a type II mouse model of diabetic nephropathy. Plos One. 14: e0212910. PMID 30865689 DOI: 10.1371/Journal.Pone.0212910  0.501
2018 Neal CR, Arkill KP, Bell JS, Betteridge KB, Bates DO, Winlove CP, Salmon AHJ, Harper SJ. Novel hemodynamic structures in the human glomerulus. American Journal of Physiology. Renal Physiology. 315: F1370-F1384. PMID 30388047 DOI: 10.1152/ajprenal.00566.2017  0.61
2018 Bates DO, Beazley-Long N, Benest AV, Ye X, Ved N, Hulse RP, Barratt S, Machado MJ, Donaldson LF, Harper SJ, Peiris-Pages M, Tortonese DJ, Oltean S, Foster RR. Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators. Comprehensive Physiology. 8: 955-979. PMID 29978898 DOI: 10.1002/Cphy.C170015  0.813
2018 Neal CR, Arkill K, Bell JS, Betteridge KB, Bates DO, Winlove CP, Salmon AH, Harper SJ. NOVEL HAEMODYNAMIC STRUCTURES IN THE HUMAN GLOMERULUS. American Journal of Physiology. Renal Physiology. PMID 29923763 DOI: 10.1152/Ajprenal.00566.2017  0.62
2018 Stevens M, Neal CR, Salmon AHJ, Bates DO, Harper SJ, Oltean S. Vascular Endothelial Growth Factor-A165b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury. Nephron. PMID 29393270 DOI: 10.1159/000485664  0.766
2017 Stevens M, Neal CR, Salmon AH, Bates DO, Harper SJ, Oltean S. VEGF-A165 b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney. The Journal of Physiology. PMID 28574576 DOI: 10.1113/Jp274481  0.753
2017 Betteridge K, Arkill K, Neal C, Harper S, Foster B, Satchell S, Bates D, Salmon A. Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function. The Journal of Physiology. PMID 28524373 DOI: 10.1113/Jp274167  0.746
2016 Stevens M, Oltean S, Harper S. Manipulation of VEGF-A splicing using natural compounds as a potential therapeutic in diabetic nephropathy Journal of the International Society of Antioxidants in Nutrition & Health. 3. DOI: 10.18143/Jisanh_V3I4_1313  0.545
2015 Bullock N, Potts J, Simpkin AJ, Koupparis A, Harper SJ, Oxley J, Oltean S. Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion. Journal of Clinical Pathology. PMID 26500332 DOI: 10.1136/Jclinpath-2015-203125  0.446
2015 Bunni J, Shelley-Fraser G, Stevenson K, Oltean S, Salmon A, Harper SJ, Carter JG, Bates DO. Circulating levels of anti-angiogenic VEGF-A isoform (VEGF-Axxxb) in colorectal cancer patients predicts tumour VEGF-A ratios. American Journal of Cancer Research. 5: 2083-9. PMID 26269767  0.74
2015 Hulse RP, Beazley-Long N, Ved N, Bestall SM, Riaz H, Singhal P, Ballmer Hofer K, Harper SJ, Bates DO, Donaldson LF. Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration. Clinical Science (London, England : 1979). 129: 741-56. PMID 26201024 DOI: 10.1042/Cs20150124  0.7
2015 Beazley-Long N, Gaston K, Harper SJ, Orlando A, Bates DO. Novel mechanisms of resistance to vemurafenib in melanoma - V600E B-Raf reversion and switching VEGF-A splice isoform expression. American Journal of Cancer Research. 5: 433-41. PMID 25628951  0.718
2015 Carter JG, Gammons MV, Damodaran G, Churchill AJ, Harper SJ, Bates DO. The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy. Angiogenesis. 18: 23-30. PMID 25274272 DOI: 10.1007/S10456-014-9444-3  0.751
2015 Hamdollah Zadeh MA, Amin EM, Hoareau-Aveilla C, Domingo E, Symonds KE, Ye X, Heesom KJ, Salmon A, D'Silva O, Betteridge KB, Williams AC, Kerr DJ, Salmon AH, Oltean S, Midgley RS, ... ... Harper SJ, et al. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Molecular Oncology. 9: 167-78. PMID 25224594 DOI: 10.1016/J.Molonc.2014.07.017  0.751
2015 Star E, Harper S, Bates D, Oltean S. Abstract A14: Use of VEGF-based splicing-sensitive fluorescent reporters to screen for anti-angiogenic molecules Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Tumang15-A14  0.747
2014 Oltean S, Qiu Y, Ferguson JK, Stevens M, Neal C, Russell A, Kaura A, Arkill KP, Harris K, Symonds C, Lacey K, Wijeyaratne L, Gammons M, Wylie E, Hulse RP, ... ... Harper SJ, et al. Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy. Journal of the American Society of Nephrology : Jasn. PMID 25542969 DOI: 10.1681/Asn.2014040350  0.81
2014 Mavrou A, Brakspear K, Hamdollah-Zadeh M, Damodaran G, Babaei-Jadidi R, Oxley J, Gillatt DA, Ladomery MR, Harper SJ, Bates DO, Oltean S. Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer. Oncogene. PMID 25381816 DOI: 10.1038/Onc.2014.360  0.738
2014 Hulse RP, Beazley-Long N, Hua J, Kennedy H, Prager J, Bevan H, Qiu Y, Fernandes ES, Gammons MV, Ballmer-Hofer K, Gittenberger de Groot AC, Churchill AJ, Harper SJ, Brain SD, Bates DO, et al. Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia. Neurobiology of Disease. 71: 245-59. PMID 25151644 DOI: 10.1016/J.Nbd.2014.08.012  0.778
2014 Bills VL, Hamdollah-Zadeh M, Soothill PW, Harper SJ, Bates DO. The role of VEGF-A165b in trophoblast survival. Bmc Pregnancy and Childbirth. 14: 278. PMID 25128406 DOI: 10.1186/1471-2393-14-278  0.753
2014 Thichanpiang P, Harper SJ, Wongprasert K, Bates DO. TNF-α-induced ICAM-1 expression and monocyte adhesion in human RPE cells is mediated in part through autocrine VEGF stimulation. Molecular Vision. 20: 781-9. PMID 24940033  0.699
2014 Arkill KP, Qvortrup K, Starborg T, Mantell JM, Knupp C, Michel CC, Harper SJ, Salmon AH, Squire JM, Bates DO, Neal CR. Resolution of the three dimensional structure of components of the glomerular filtration barrier. Bmc Nephrology. 15: 24. PMID 24484633 DOI: 10.1186/1471-2369-15-24  0.621
2013 Bates DO, Mavrou A, Qiu Y, Carter JG, Hamdollah-Zadeh M, Barratt S, Gammons MV, Millar AB, Salmon AH, Oltean S, Harper SJ. Detection of VEGF-A(xxx)b isoforms in human tissues. Plos One. 8: e68399. PMID 23935865 DOI: 10.1371/Journal.Pone.0068399  0.759
2013 Gammons MV, Fedorov O, Ivison D, Du C, Clark T, Hopkins C, Hagiwara M, Dick AD, Cox R, Harper SJ, Hancox JC, Knapp S, Bates DO. Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD. Investigative Ophthalmology & Visual Science. 54: 6052-62. PMID 23887803 DOI: 10.1167/Iovs.13-12422  0.739
2013 Beazley-Long N, Hua J, Jehle T, Hulse RP, Dersch R, Lehrling C, Bevan H, Qiu Y, Lagrèze WA, Wynick D, Churchill AJ, Kehoe P, Harper SJ, Bates DO, Donaldson LF. VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro. The American Journal of Pathology. 183: 918-29. PMID 23838428 DOI: 10.1016/J.Ajpath.2013.05.031  0.761
2013 Gammons MV, Dick AD, Harper SJ, Bates DO. SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity. Investigative Ophthalmology & Visual Science. 54: 5797-806. PMID 23761094 DOI: 10.1167/Iovs.13-11634  0.747
2012 Bates DO, Catalano PJ, Symonds KE, Varey AH, Ramani P, O'Dwyer PJ, Giantonio BJ, Meropol NJ, Benson AB, Harper SJ. Predictive value of the antiangiogenic VEGF splice variant expression for bevacizumab efficacy in the phase III trial of bevacizumab and FOLFOX4 versus FOLFOX4 in previously treated patients with advanced colorectal cancer (ECOG E3200T2). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 545. PMID 27983263 DOI: 10.1200/Jco.2012.30.4_Suppl.545  0.701
2012 Bates DO, Catalano PJ, Symonds KE, Varey AH, Ramani P, O'Dwyer PJ, Giantonio BJ, Meropol NJ, Benson AB, Harper SJ. Association between VEGF splice isoforms and progression-free survival in metastatic colorectal cancer patients treated with bevacizumab. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6384-91. PMID 23104894 DOI: 10.1158/1078-0432.Ccr-12-2223  0.71
2012 Oltean S, Gammons M, Hulse R, Hamdollah-Zadeh M, Mavrou A, Donaldson L, Salmon AH, Harper SJ, Ladomery MR, Bates DO. SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases. Biochemical Society Transactions. 40: 831-5. PMID 22817743 DOI: 10.1042/Bst20120051  0.744
2012 Oltean S, Neal CR, Mavrou A, Patel P, Ahad T, Alsop C, Lee T, Sison K, Qiu Y, Harper SJ, Bates DO, Salmon AH. VEGF165b overexpression restores normal glomerular water permeability in VEGF164-overexpressing adult mice. American Journal of Physiology. Renal Physiology. 303: F1026-36. PMID 22811490 DOI: 10.1152/Ajprenal.00410.2011  0.777
2012 Salmon AH, Ferguson JK, Burford JL, Gevorgyan H, Nakano D, Harper SJ, Bates DO, Peti-Peterdi J. Loss of the endothelial glycocalyx links albuminuria and vascular dysfunction. Journal of the American Society of Nephrology : Jasn. 23: 1339-50. PMID 22797190 DOI: 10.1681/Asn.2012010017  0.712
2012 Qiu Y, Seager M, Osman A, Castle-Miller J, Bevan H, Tortonese DJ, Murphy D, Harper SJ, Fraser HM, Donaldson LF, Bates DO. Ovarian VEGF(165)b expression regulates follicular development, corpus luteum function and fertility. Reproduction (Cambridge, England). 143: 501-11. PMID 22232745 DOI: 10.1530/Rep-11-0091  0.764
2011 Woolard J, Vousden W, Moss SJ, Krishnakumar A, Gammons MV, Nowak DG, Dixon N, Micklefield J, Spannhoff A, Bedford MT, Gregory MA, Martin CJ, Leadlay PF, Zhang MQ, Harper SJ, et al. Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms. Chemical Science (Royal Society of Chemistry : 2010). 2011: 273-278. PMID 22822423 DOI: 10.1039/C0Sc00297F  0.766
2011 Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, ... ... Harper SJ, et al. WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer Cell. 20: 768-80. PMID 22172722 DOI: 10.1016/J.Ccr.2011.10.016  0.743
2011 Rennel ES, Regula JT, Harper SJ, Thomas M, Klein C, Bates DO. A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis. Microcirculation (New York, N.Y. : 1994). 18: 598-607. PMID 21851472 DOI: 10.1111/J.1549-8719.2011.00120.X  0.718
2011 Bills VL, Salmon AH, Harper SJ, Overton TG, Neal CR, Jeffery B, Soothill PW, Bates DO. Impaired vascular permeability regulation caused by the VEGF165b splice variant in pre-eclampsia Bjog: An International Journal of Obstetrics and Gynaecology. 118: 1253-1261. PMID 21668772 DOI: 10.1111/J.1471-0528.2011.02925.X  0.742
2010 Harper SJ, Bates DO. Glomerular filtration barrier and molecular segregation: guilty as charged? Journal of the American Society of Nephrology : Jasn. 21: 2009-11. PMID 21071522 DOI: 10.1681/Asn.2010101071  0.601
2010 Qiu Y, Ferguson J, Oltean S, Neal CR, Kaura A, Bevan H, Wood E, Sage LM, Lanati S, Nowak DG, Salmon AH, Bates D, Harper SJ. Overexpression of VEGF165b in podocytes reduces glomerular permeability. Journal of the American Society of Nephrology : Jasn. 21: 1498-509. PMID 20688932 DOI: 10.1681/Asn.2009060617  0.747
2010 Peiris-Pagès M, Harper SJ, Bates DO, Ramani P. Balance of pro- versus anti-angiogenic splice isoforms of vascular endothelial growth factor as a regulator of neuroblastoma growth. The Journal of Pathology. 222: 138-47. PMID 20662003 DOI: 10.1002/Path.2746  0.791
2010 Hua J, Spee C, Kase S, Rennel ES, Magnussen AL, Qiu Y, Varey A, Dhayade S, Churchill AJ, Harper SJ, Bates DO, Hinton DR. Recombinant human VEGF165b inhibits experimental choroidal neovascularization. Investigative Ophthalmology & Visual Science. 51: 4282-8. PMID 20237252 DOI: 10.1167/Iovs.09-4360  0.759
2010 Magnussen AL, Rennel ES, Hua J, Bevan HS, Beazley Long N, Lehrling C, Gammons M, Floege J, Harper SJ, Agostini HT, Bates DO, Churchill AJ. VEGF-A165b is cytoprotective and antiangiogenic in the retina. Investigative Ophthalmology & Visual Science. 51: 4273-81. PMID 20237249 DOI: 10.1167/Iovs.09-4296  0.761
2010 Varet J, Douglas SK, Gilmartin L, Medford AR, Bates DO, Harper SJ, Millar AB. VEGF in the lung: a role for novel isoforms. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L768-74. PMID 20228180 DOI: 10.1152/Ajplung.00353.2009  0.746
2010 Nowak DG, Amin EM, Rennel ES, Hoareau-Aveilla C, Gammons M, Damodoran G, Hagiwara M, Harper SJ, Woolard J, Ladomery MR, Bates DO. Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis. The Journal of Biological Chemistry. 285: 5532-40. PMID 19906640 DOI: 10.1074/Jbc.M109.074930  0.768
2009 Qiu Y, Hoareau-Aveilla C, Oltean S, Harper SJ, Bates DO. The anti-angiogenic isoforms of VEGF in health and disease. Biochemical Society Transactions. 37: 1207-13. PMID 19909248 DOI: 10.1042/Bst0371207  0.79
2009 Rennel ES, Varey AH, Churchill AJ, Wheatley ER, Stewart L, Mather S, Bates DO, Harper SJ. VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo. British Journal of Cancer. 101: 1183-93. PMID 19707198 DOI: 10.1038/Sj.Bjc.6605249  0.76
2009 Woolard J, Bevan HS, Harper SJ, Bates DO. Molecular diversity of VEGF-A as a regulator of its biological activity. Microcirculation (New York, N.Y. : 1994). 16: 572-92. PMID 19521900 DOI: 10.1080/10739680902997333  0.787
2009 Rennel ES, Harper SJ, Bates DO. Therapeutic potential of manipulating VEGF splice isoforms in oncology. Future Oncology (London, England). 5: 703-12. PMID 19519209 DOI: 10.2217/Fon.09.33  0.76
2009 Salmon AHJ, Neal CR, Harper SJ. New aspects of glomerular filtration barrier structure and function: Five layers (at least) not three Current Opinion in Nephrology and Hypertension. 18: 197-205. PMID 19365184 DOI: 10.1097/Mnh.0B013E328329F837  0.352
2009 Salmon AHJ, Neal CR, Sage LM, Glass CA, Harper SJ, Bates DO. Angiopoietin-1 alters microvascular permeability coefficients in vivo via modification of endothelial glycocalyx Cardiovascular Research. 83: 24-33. PMID 19297368 DOI: 10.1093/Cvr/Cvp093  0.735
2009 Bills VL, Varet J, Millar A, Harper SJ, Soothill PW, Bates DO. Failure to up-regulate VEGF165b in maternal plasma is a first trimester predictive marker for pre-eclampsia. Clinical Science (London, England : 1979). 116: 265-72. PMID 18826376 DOI: 10.1042/Cs20080270  0.707
2009 Augello A, Vergani A, Jurewicz M, Dada S, D'Addio F, Mocci A, Sayegh M, Abdi R, Fiorina P, Zhang Q, Shi Y, Li Y, Zhang Y, Lee V, Zheng D, ... ... Harper SJ, et al. Diabetes mellitus - basic research Ndt Plus. 2. DOI: 10.1093/Ndtplus/2.S2.7  0.593
2008 Bevan HS, Van Den Akker NMS, Qiu Y, Polman JAE, Foster RR, Yem J, Nishikawa A, Satchell SC, Harper SJ, Gittenberger-De Groot AC, Bates DO. The alternatively spliced anti-angiogenic family of VEGF isoforms VEGF xxxb in human kidney development Nephron - Physiology. 110. PMID 19039247 DOI: 10.1159/000177614  0.815
2008 Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics? Nature Reviews. Cancer. 8: 880-7. PMID 18923433 DOI: 10.1038/Nrc2505  0.772
2008 Nowak DG, Woolard J, Amin EM, Konopatskaya O, Saleem MA, Churchill AJ, Ladomery MR, Harper SJ, Bates DO. Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors. Journal of Cell Science. 121: 3487-95. PMID 18843117 DOI: 10.1242/Jcs.016410  0.756
2008 Rennel ES, Hamdollah-Zadeh MA, Wheatley ER, Magnussen A, Schüler Y, Kelly SP, Finucane C, Ellison D, Cebe-Suarez S, Ballmer-Hofer K, Mather S, Stewart L, Bates DO, Harper SJ. Recombinant human VEGF165b protein is an effective anti-cancer agent in mice. European Journal of Cancer (Oxford, England : 1990). 44: 1883-94. PMID 18657413 DOI: 10.1016/J.Ejca.2008.05.027  0.776
2008 Kawamura H, Li X, Harper SJ, Bates DO, Claesson-Welsh L. Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity. Cancer Research. 68: 4683-92. PMID 18559514 DOI: 10.1158/0008-5472.Can-07-6577  0.783
2008 Benest AV, Stone OA, Miller WH, Glover CP, Uney JB, Baker AH, Harper SJ, Bates DO. Arteriolar genesis and angiogenesis induced by endothelial nitric oxide synthase overexpression results in a mature vasculature. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1462-8. PMID 18497305 DOI: 10.1161/Atvbaha.108.169375  0.779
2008 Varey AHR, Rennel ES, Qiu Y, Bevan HS, Perrin RM, Raffy S, Dixon AR, Paraskeva C, Zaccheo O, Hassan AB, Harper SJ, Bates DO. VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: Balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy British Journal of Cancer. 98: 1366-1379. PMID 18349829 DOI: 10.1038/Sj.Bjc.6604308  0.841
2008 Rennel E, Waine E, Guan H, Schüler Y, Leenders W, Woolard J, Sugiono M, Gillatt D, Kleinerman E, Bates D, Harper S. The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice. British Journal of Cancer. 98: 1250-7. PMID 18349828 DOI: 10.1038/Sj.Bjc.6604309  0.762
2008 Benest AV, Harper SJ, Herttuala SY, Alitalo K, Bates DO. VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis Cardiovascular Research. 78: 315-323. PMID 18065770 DOI: 10.1093/Cvr/Cvm094  0.753
2008 Qiu Y, Bevan H, Weeraperuma S, Wratting D, Murphy D, Neal CR, Bates DO, Harper SJ. Mammary alveolar development during lactation is inhibited by the endogenous antiangiogenic growth factor isoform, VEGF165b Faseb Journal. 22: 1104-1112. PMID 18032632 DOI: 10.1096/Fj.07-9718Com  0.729
2008 Bevan HS, Akker NMSvd, Qiu Y, Polman JAE, Foster RR, Yem J, Nishikawa A, Satchell SC, Harper SJ, Groot ACG, Bates DO. Contents Vol. 110, 2008 Nephron Physiology. 110. DOI: 10.1159/000187120  0.561
2008 Gopi SS, Zadeh MH, Sen C, Harper SJ, Bates DO, Gillatt DA. INVIVO EXPRESSION OF VEGF 165 b, AN INHIBITORY SPLICE VARIANT OF VEGF165 IN TRANSITIONAL CELL CARCINOMA OF THE BLADDER Journal of Urology. 179: 316-316. DOI: 10.1016/S0022-5347(08)60925-8  0.71
2008 Gopi S, H-Zadeh M, Sen C, Harper S, Bates D, Gillatt D. SCHU-01: VEGF165b, an Inhibitory Splice Variant of VEGF165 in Transitional Cell Carcinoma of the Bladder: In Vivo Expression Urology. 72: S3. DOI: 10.1016/J.Urology.2008.08.004  0.661
2007 Perrin RM, Harper SJ, Bates DO. A role for the endothelial glycocalyx in regulating microvascular permeability in diabetes mellitus Cell Biochemistry and Biophysics. 49: 65-72. PMID 17906361 DOI: 10.1007/S12013-007-0041-6  0.786
2007 Perrin RM, Harper SJ, Corrall R, Bates DO. Hyperglycemia stimulates a sustained increase in hydraulic conductivity in vivo without any change in reflection coefficient Microcirculation. 14: 683-696. PMID 17885994 DOI: 10.1080/10739680701436129  0.765
2007 Salmon AH, Toma I, Sipos A, Muston PR, Harper SJ, Bates DO, Neal CR, Peti-Peterdi J. Evidence for restriction of fluid and solute movement across the glomerular capillary wall by the subpodocyte space. American Journal of Physiology. Renal Physiology. 293: F1777-86. PMID 17804486 DOI: 10.1152/Ajprenal.00187.2007  0.595
2007 Neal CR, Muston PR, Njegovan D, Verrill R, Harper SJ, Deen WM, Bates DO. Glomerular filtration into the subpodocyte space is highly restricted under physiological perfusion conditions. American Journal of Physiology. Renal Physiology. 293: F1787-98. PMID 17715264 DOI: 10.1152/Ajprenal.00157.2007  0.597
2007 Cross SE, Richards SK, Clark A, Benest AV, Bates DO, Mathieson PW, Johnson PR, Harper SJ, Smith RM. Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs. Diabetologia. 50: 1423-32. PMID 17476476 DOI: 10.1007/S00125-007-0670-8  0.745
2007 Ladomery MR, Harper SJ, Bates DO. Alternative splicing in angiogenesis: the vascular endothelial growth factor paradigm. Cancer Letters. 249: 133-42. PMID 17027147 DOI: 10.1016/J.Canlet.2006.08.015  0.78
2007 Salmon A, Toma I, Harper S, Bates D, Neal C, Peti‐Peterdi J. Multiphoton imaging of sub‐podocyte space in isolated perfused glomeruli The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A503-A  0.575
2007 Nowak DG, Amin E, Ladomery MR, Harper SJ, Bates DO. Selective upregulation of anti‐angiogenic splice variants of VEGF by TGF‐β1 is mediated by Cdc2‐like kinase family (Clk) and p38 MAPK The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A248-D  0.667
2007 Gopi S, Zadeh M, Harper S, Bates D, Gillatt D. MP-04.12: Anti angiogenic VEGF165b is an inhibitory splice variant of VEGF in transitional cell carcinoma of the bladder Urology. 70: 61. DOI: 10.1016/J.Urology.2007.06.241  0.67
2006 Benest AV, Salmon AH, Wang W, Glover CP, Uney J, Harper SJ, Bates DO. VEGF and angiopoietin-1 stimulate different angiogenic phenotypes that combine to enhance functional neovascularization in adult tissue Microcirculation. 13: 423-437. PMID 16864410 DOI: 10.1080/10739680600775940  0.768
2006 Foster RR, Satchell SC, Seckley J, Emmett MS, Joory K, Xing CY, Saleem MA, Mathieson PW, Bates DO, Harper SJ. VEGF-C promotes survival in podocytes American Journal of Physiology - Renal Physiology. 291. PMID 16525158 DOI: 10.1152/Ajprenal.00431.2005  0.819
2006 Bates DO, MacMillan PP, Manjaly JG, Qiu Y, Hudson SJ, Bevan HS, Hunter AJ, Soothill PW, Read M, Donaldson LF, Harper SJ. The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term. Clinical Science (London, England : 1979). 110: 575-85. PMID 16451124 DOI: 10.1042/Cs20050292  0.761
2006 Glass CA, Harper SJ, Bates DO. The anti-angiogenic VEGF isoform VEGF165b transiently increases hydraulic conductivity, probably through VEGF receptor 1 in vivo. The Journal of Physiology. 572: 243-57. PMID 16423853 DOI: 10.1113/Jphysiol.2005.103127  0.78
2006 Salmon AHJ, Neal CR, Bates DO, Harper SJ. Vascular endothelial growth factor increases the ultrafiltration coefficient in isolated intact Wistar rat glomeruli Journal of Physiology. 570: 141-156. PMID 16239266 DOI: 10.1113/Jphysiol.2005.099184  0.752
2005 Bates DO, Harper SJ. Therapeutic potential of inhibitory VEGF splice variants. Future Oncology (London, England). 1: 467-73. PMID 16556023 DOI: 10.2217/14796694.1.4.467  0.749
2005 Perrin RM, Konopatskaya O, Qiu Y, Harper S, Bates DO, Churchill AJ. Diabetic retinopathy is associated with a switch in splicing from anti- to pro-angiogenic isoforms of vascular endothelial growth factor Diabetologia. 48: 2422-2427. PMID 16193288 DOI: 10.1007/S00125-005-1951-8  0.852
2005 Neal CR, Crook H, Bell E, Harper SJ, Bates DO. Three-dimensional reconstruction of glomeruli by electron microscopy reveals a distinct restrictive urinary subpodocyte space Journal of the American Society of Nephrology. 16: 1223-1235. PMID 15829713 DOI: 10.1681/Asn.2004100822  0.596
2005 Coward RJ, Foster RR, Patton D, Ni L, Lennon R, Bates DO, Harper SJ, Mathieson PW, Saleem MA. Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes. Journal of the American Society of Nephrology : Jasn. 16: 629-37. PMID 15659563 DOI: 10.1681/Asn.2004030172  0.706
2005 Foster RR, Saleem MA, Mathieson PW, Bates DO, Harper SJ. Vascular endothelial growth factor and nephrin interact and reduce apoptosis in human podocytes American Journal of Physiology - Renal Physiology. 288. PMID 15339792 DOI: 10.1152/Ajprenal.00146.2004  0.817
2004 Woolard J, Wang WY, Bevan HS, Qiu Y, Morbidelli L, Pritchard-Jones RO, Cui TG, Sugiono M, Waine E, Perrin R, Foster R, Digby-Bell J, Shields JD, Whittles CE, Mushens RE, ... ... Harper SJ, et al. VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression. Cancer Research. 64: 7822-35. PMID 15520188 DOI: 10.1158/0008-5472.Can-04-0934  0.856
2004 Wang WY, Whittles CE, Harper SJ, Bates DO. An adenovirus-mediated gene-transfer model of angiogenesis in rat mesentery. Microcirculation (New York, N.Y. : 1994). 11: 361-75. PMID 15280075 DOI: 10.1080/10739680490437568  0.701
2004 Neal CR, Hunter AJ, Harper SJ, Soothill PW, Bates DO. Plasma from women with severe pre-eclampsia increases microvascular permeability in an animal model in vivo Clinical Science. 107: 399-405. PMID 15186215 DOI: 10.1042/Cs20040018  0.66
2004 Shields JD, Borsetti M, Rigby H, Harper SJ, Mortimer PS, Levick JR, Orlando A, Bates DO. Lymphatic density and metastatic spread in human malignant melanoma. British Journal of Cancer. 90: 693-700. PMID 14760386 DOI: 10.1038/Sj.Bjc.6601571  0.576
2004 Cui TG, Foster RR, Saleem M, Mathieson PW, Gillatt DA, Bates DO, Harper SJ. Differentiated human podocytes endogenously express an inhibitory isoform of vascular endothelial growth factor (VEGF165b) mRNA and protein American Journal of Physiology - Renal Physiology. 286. PMID 14644752 DOI: 10.1152/Ajprenal.00337.2003  0.837
2004 Salmon AHJ, Bates DO, Harper SJ. PC35 THE ULTRAFILTRATION COEFFICIENT (LpA) OF MAMMALIAN GLOMERULI DOES NOT DISPLAY RECTIFICATION Microcirculation. 11: 550-551. DOI: 10.1080/10739680490488742  0.54
2004 Neal CR, Bell E, Crook H, Bates DO, Harper SJ. PC33 3D RECONSTRUCTION OF THE GLOMERULAR CAPILLARY TUFT SHOWS A SECOND RESTRICTIVE SPACE BETWEEN THE GLOMERULAR FILTRATION BARRIER (GFB) AND PERIPHERAL BOWMAN'S SPACE Microcirculation. 11: 550-550. DOI: 10.1080/10739680490488724  0.545
2004 Foster RR, Mathieson PW, Saleem MA, Bates DO, Harper SJ. PC32 VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) ACTS THROUGH NEPHRIN TO REDUCE APOPTOSIS IN HUMAN CONDITIONALLY IMMORTALISED PODOCYTES (HCIPS) Microcirculation. 11: 549-550. DOI: 10.1080/10739680490488715  0.819
2004 Benest AV, Harper SJ, Bates DO. PC1 MEASUREMENT OF BLOOD FLOW USING A NON-RADIOACTIVE CLEARANCE TECHNIQUE IN RAT MESENTERIC TISSUE [moor instruments award] Microcirculation. 11: 539-539. DOI: 10.1080/10739680490488409  0.548
2004 Neal CR, Crook H, Bell E, Bates DO, Harper SJ. OC25 RECONSTRUCTION OF THE SUB-PODOCYTE SPACE (SPS) REVEALS SIGNIFICANT PATHLENGTH AND RESTRICTION TO FLUID FLOW IN THE REMAINDER OF BOWMAN'S SPACE Microcirculation. 11: 537-537. DOI: 10.1080/10739680490488355  0.535
2004 Wang W-, Whittles CE, Harper SJ, Bates DO. OC22 CHARACTERISATION OF FILOPODIA OF ENDOTHELIAL SPROUT TIP CELLS IN RAT MESENTERIC ANGIOGENESIS Microcirculation. 11: 536-536. DOI: 10.1080/10739680490488328  0.693
2004 Bevan HS, Woolard J, Harper SJ, Bates DO. OC21 VEGF165b INHIBITS VEGF165 MEDIATED VEGF-R2 PHOSPHORYLATION AND AKT PHOSPHORYLATION Microcirculation. 11: 536-536. DOI: 10.1080/10739680490488319  0.688
2004 Jones ROP, Shields JD, Woolard J, Harper SJ, Bates DO. OC11 DIFFERENTIAL VEGF ISOFORM EXPRESSION REGULATES GROWTH OF XENOGRAFTED MALIGNANT MELANOMA [terence Ryan award] Microcirculation. 11: 532-533. DOI: 10.1080/10739680490488210  0.683
2003 Bates DO, Harper SJ. Regulation of vascular permeability by vascular endothelial growth factors. Vascular Pharmacology. 39: 225-37. PMID 12747962 DOI: 10.1016/S1537-1891(03)00011-9  0.758
2003 Harper SJ, Bates DO. Endothelial permeability in uremia. Kidney International. Supplement. S41-4. PMID 12694306 DOI: 10.1046/J.1523-1755.63.S84.15.X  0.728
2003 Foster RR, Hole R, Anderson K, Satchell SC, Coward RJ, Mathieson PW, Gillatt DA, Saleem MA, Bates DO, Harper SJ. Functional evidence that vascular endothelial growth factor may act as an autocrine factor on human podocytes American Journal of Physiology - Renal Physiology. 284. PMID 12620928 DOI: 10.1152/Ajprenal.00276.2002  0.797
2003 Whittles CE, Pocock TM, Wedge SR, Kendrew J, Hennequin LF, Harper SJ, Bates DO. ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity. Microcirculation (New York, N.Y. : 1994). 9: 513-22. PMID 12483548 DOI: 10.1038/Sj.Mn.7800164  0.751
2002 Bates DO, Cui TG, Doughty JM, Winkler M, Sugiono M, Shields JD, Peat D, Gillatt D, Harper SJ. VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Research. 62: 4123-31. PMID 12124351  0.729
2002 Harper SJ, Tomson CR, Bates DO. Human uremic plasma increases microvascular permeability to water and proteins in vivo. Kidney International. 61: 1416-22. PMID 11918748 DOI: 10.1046/J.1523-1755.2002.00252.X  0.614
2002 Harper SJ, Downs L, Tomson CR, Dwight JS, Bolton C. Elevated plasma vascular endothelial growth factor levels in non-diabetic predialysis uraemia. Nephron. 90: 341-3. PMID 11867956 DOI: 10.1159/000049071  0.541
2001 HARPER SJ, XING CY, WHITTLE C, PARRY R, GILLATT D, PEAT D, MATHIESON PW. Expression of neuropilin-1 by human glomerular epithelial cells in vitro and in vivo Clinical Science. 101: 439. DOI: 10.1042/Cs1010439  0.558
2001 HARPER SJ, XING CY, WHITTLE C, PARRY R, GILLATT D, PEAT D, MATHIESON PW. Expression of neuropilin-1 by human glomerular epithelial cells in vitro and in vivo Clinical Science. 101: 439-446. DOI: 10.1042/cs1010439  0.471
1999 Bailey E, Bottomley MJ, Westwell S, Pringle JH, Furness PN, Feehally J, Brenchley PE, Harper SJ. Vascular endothelial growth factor mRNA expression in minimal change, membranous, and diabetic nephropathy demonstrated by non-isotopic in situ hybridisation. Journal of Clinical Pathology. 52: 735-8. PMID 10674029 DOI: 10.1136/jcp.52.10.735  0.507
1999 WHITTLE C, GILLESPIE K, HARRISON R, MATHIESON PW, HARPER SJ. Heterogeneous vascular endothelial growth factor (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant Clinical Science. 97: 303. DOI: 10.1042/CS19990016  0.454
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