Yukiko Gotoh - Publications

Affiliations: 
Institute of Molecular and Cellular Biosciences University of Tokyo, Bunkyō-ku, Tōkyō-to, Japan 

118 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kuwayama N, Kujirai T, Kishi Y, Hirano R, Echigoya K, Fang L, Watanabe S, Nakao M, Suzuki Y, Ishiguro KI, Kurumizaka H, Gotoh Y. HMGA2 directly mediates chromatin condensation in association with neuronal fate regulation. Nature Communications. 14: 6420. PMID 37828010 DOI: 10.1038/s41467-023-42094-9  0.37
2023 Fang L, Kuniya T, Harada Y, Yasuda O, Maeda N, Suzuki Y, Kawaguchi D, Gotoh Y. TIMP3 promotes the maintenance of neural stem-progenitor cells in the mouse subventricular zone. Frontiers in Neuroscience. 17: 1149603. PMID 37456993 DOI: 10.3389/fnins.2023.1149603  0.428
2021 Harada Y, Yamada M, Imayoshi I, Kageyama R, Suzuki Y, Kuniya T, Furutachi S, Kawaguchi D, Gotoh Y. Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module. Nature Communications. 12: 6562. PMID 34772946 DOI: 10.1038/s41467-021-26605-0  0.814
2021 Tsuboi M, Gotoh Y. Analysis of histone modifications in mouse neocortical neural progenitor-stem cells at various developmental stages. Star Protocols. 2: 100763. PMID 34467231 DOI: 10.1016/j.xpro.2021.100763  0.799
2021 Kishi Y, Gotoh Y. Isolation of genetically manipulated neural progenitors and immature neurons from embryonic mouse neocortex by FACS. Star Protocols. 2: 100540. PMID 34041504 DOI: 10.1016/j.xpro.2021.100540  0.353
2021 Utsunomiya S, Kishi Y, Tsuboi M, Kawaguchi D, Gotoh Y, Abe M, Sakimura K, Maeda K, Takemoto H. Ezh1 regulates expression of Cpg15/Neuritin in mouse cortical neurons. Drug Discoveries & Therapeutics. PMID 33678755 DOI: 10.5582/ddt.2021.01017  0.798
2021 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y. Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells (Dayton, Ohio). PMID 33609411 DOI: 10.1002/stem.3359  0.465
2021 Omiya H, Yamaguchi S, Watanabe T, Kuniya T, Harada Y, Kawaguchi D, Gotoh Y. BMP signaling suppresses Gemc1 expression and ependymal differentiation of mouse telencephalic progenitors. Scientific Reports. 11: 613. PMID 33436697 DOI: 10.1038/s41598-020-79610-6  0.411
2020 Nagahama K, Sakoori K, Watanabe T, Kishi Y, Kawaji K, Koebis M, Nakao K, Gotoh Y, Aiba A, Uesaka N, Kano M. Setd1a Insufficiency in Mice Attenuates Excitatory Synaptic Function and Recapitulates Schizophrenia-Related Behavioral Abnormalities. Cell Reports. 32: 108126. PMID 32937141 DOI: 10.1016/J.Celrep.2020.108126  0.763
2020 Imaizumi Y, Furutachi S, Watanabe T, Miya H, Kawaguchi D, Gotoh Y. Role of the imprinted allele of the Cdkn1c gene in mouse neocortical development. Scientific Reports. 10: 1884. PMID 32024956 DOI: 10.1038/S41598-020-58629-9  0.799
2019 Tsuboi M, Gotoh Y. Endfoot regrowth for neural stem cell renewal. Nature Cell Biology. PMID 31871316 DOI: 10.1038/S41556-019-0448-5  0.804
2019 Sakai H, Fujii Y, Kuwayama N, Kawaji K, Gotoh Y, Kishi Y. Plag1 regulates neuronal gene expression and neuronal differentiation of neocortical neural progenitor cells. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 31442350 DOI: 10.1111/Gtc.12718  0.512
2019 Tsuboi M, Hirabayashi Y, Gotoh Y. Diverse gene regulatory mechanisms mediated by Polycomb group proteins during neural development. Current Opinion in Neurobiology. 59: 164-173. PMID 31398486 DOI: 10.1016/J.Conb.2019.07.003  0.793
2019 Gotoh Y. Chromatin-level regulation of neural stem/progenitor cell fate Ibro Reports. 6: S4. DOI: 10.1016/j.ibror.2019.07.178  0.359
2018 Kishi Y, Gotoh Y. Regulation of Chromatin Structure During Neural Development. Frontiers in Neuroscience. 12: 874. PMID 30618540 DOI: 10.3389/Fnins.2018.00874  0.347
2018 Tsuboi M, Kishi Y, Yokozeki W, Koseki H, Hirabayashi Y, Gotoh Y. Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex. Developmental Cell. 47: 758-772.e5. PMID 30562514 DOI: 10.1016/J.Devcel.2018.11.018  0.804
2018 Okazaki T, Gotoh Y. An Unexpected Calm: Mfge8 Controls Stem Cell Quiescence and Maintenance. Cell Stem Cell. 23: 311-312. PMID 30193126 DOI: 10.1016/J.Stem.2018.08.006  0.471
2018 Lanjakornsiripan D, Pior BJ, Kawaguchi D, Furutachi S, Tahara T, Katsuyama Y, Suzuki Y, Fukazawa Y, Gotoh Y. Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers. Nature Communications. 9: 1623. PMID 29691400 DOI: 10.1038/S41467-018-03940-3  0.76
2017 Kawai H, Kawaguchi D, Kuebrich BD, Kitamoto T, Yamaguchi M, Gotoh Y, Furutachi S. Area-specific regulation of quiescent neural stem cells by Notch3 in the adult mouse subependymal zone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29101245 DOI: 10.1523/Jneurosci.0001-17.2017  0.826
2016 Imaizumi Y, Kawaguchi D, Furutachi S, Gotoh Y. [Embryonic origin of adult neural stem cells]. Seikagaku. the Journal of Japanese Biochemical Society. 88: 766-70. PMID 29624352  0.805
2016 Itoh Y, Higuchi M, Oishi K, Kishi Y, Okazaki T, Sakai H, Miyata T, Nakajima K, Gotoh Y. PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex. Proceedings of the National Academy of Sciences of the United States of America. 113: E2955-64. PMID 27170189 DOI: 10.1073/Pnas.1516321113  0.435
2016 Nagao M, Ogata T, Sawada Y, Gotoh Y. Zbtb20 promotes astrocytogenesis during neocortical development. Nature Communications. 7: 11102. PMID 27000654 DOI: 10.1038/Ncomms11102  0.445
2016 Itoh Y, Higuchi M, Oishi K, Kishi Y, Okazaki T, Sakai H, Miyata T, Nakajima K, Gotoh Y. PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex Proceedings of the National Academy of Sciences of the United States of America. 113: E2955-E2964. DOI: 10.1073/pnas.1516321113  0.322
2015 Okazaki T, Higuchi M, Takeda K, Iwatsuki-Horimoto K, Kiso M, Miyagishi M, Yanai H, Kato A, Yoneyama M, Fujita T, Taniguchi T, Kawaoka Y, Ichijo H, Gotoh Y. The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response. Science Signaling. 8: ra78. PMID 26243192 DOI: 10.1126/Scisignal.Aab1883  0.357
2015 Furutachi S, Miya H, Watanabe T, Kawai H, Yamasaki N, Harada Y, Imayoshi I, Nelson M, Nakayama KI, Hirabayashi Y, Gotoh Y. Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells. Nature Neuroscience. 18: 657-65. PMID 25821910 DOI: 10.1038/Nn.3989  0.798
2015 Oshiro H, Hirabayashi Y, Furuta Y, Okabe S, Gotoh Y. Up-regulation of HP1γ expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 20: 108-20. PMID 25441120 DOI: 10.1111/Gtc.12205  0.72
2014 Morimoto-Suzki N, Hirabayashi Y, Tyssowski K, Shinga J, Vidal M, Koseki H, Gotoh Y. The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development. Development (Cambridge, England). 141: 4343-53. PMID 25344075 DOI: 10.1242/Dev.112276  0.752
2014 Nagao M, Lanjakornsiripan D, Itoh Y, Kishi Y, Ogata T, Gotoh Y. High mobility group nucleosome-binding family proteins promote astrocyte differentiation of neural precursor cells. Stem Cells (Dayton, Ohio). 32: 2983-97. PMID 25069414 DOI: 10.1002/Stem.1787  0.455
2014 Kuwahara A, Sakai H, Xu Y, Itoh Y, Hirabayashi Y, Gotoh Y. Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development. Plos One. 9: e94408. PMID 24832538 DOI: 10.1371/Journal.Pone.0094408  0.762
2014 Tyssowski K, Kishi Y, Gotoh Y. Chromatin regulators of neural development. Neuroscience. 264: 4-16. PMID 24144622 DOI: 10.1016/J.Neuroscience.2013.10.008  0.395
2013 Itoh Y, Tyssowski K, Gotoh Y. Transcriptional coupling of neuronal fate commitment and the onset of migration. Current Opinion in Neurobiology. 23: 957-64. PMID 23973158 DOI: 10.1016/J.Conb.2013.08.003  0.471
2013 Kawaguchi D, Furutachi S, Kawai H, Hozumi K, Gotoh Y. Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis. Nature Communications. 4: 1880. PMID 23695674 DOI: 10.1038/Ncomms2895  0.81
2013 Furutachi S, Matsumoto A, Nakayama KI, Gotoh Y. p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis. The Embo Journal. 32: 970-81. PMID 23481253 DOI: 10.1038/Emboj.2013.50  0.799
2013 Itoh Y, Moriyama Y, Hasegawa T, Endo TA, Toyoda T, Gotoh Y. Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nature Neuroscience. 16: 416-25. PMID 23434913 DOI: 10.1038/Nn.3336  0.464
2013 Fujii Y, Kishi Y, Gotoh Y. IMP2 regulates differentiation potentials of mouse neocortical neural precursor cells. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 18: 79-89. PMID 23331702 DOI: 10.1111/Gtc.12024  0.455
2013 Higuchi M, Kihara R, Okazaki T, Aoki I, Suetsugu S, Gotoh Y. Akt1 promotes focal adhesion disassembly and cell motility through phosphorylation of FAK in growth factor-stimulated cells. Journal of Cell Science. 126: 745-55. PMID 23264741 DOI: 10.1242/Jcs.112722  0.357
2013 Aoki I, Higuchi M, Gotoh Y. NEDDylation controls the target specificity of E2F1 and apoptosis induction. Oncogene. 32: 3954-64. PMID 23001041 DOI: 10.1038/Onc.2012.428  0.369
2012 Onoguchi M, Hirabayashi Y, Koseki H, Gotoh Y. A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development. Proceedings of the National Academy of Sciences of the United States of America. 109: 16939-44. PMID 23027973 DOI: 10.1073/Pnas.1202956109  0.722
2012 Kishi Y, Kondo S, Gotoh Y. Transcriptional activation of mouse major satellite regions during neuronal differentiation. Cell Structure and Function. 37: 101-10. PMID 22976370 DOI: 10.1247/Csf.12009  0.431
2012 Kishi Y, Fujii Y, Hirabayashi Y, Gotoh Y. HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells. Nature Neuroscience. 15: 1127-33. PMID 22797695 DOI: 10.1038/Nn.3165  0.741
2012 Watatani K, Hirabayashi Y, Itoh Y, Gotoh Y. PDK1 regulates the generation of oligodendrocyte precursor cells at an early stage of mouse telencephalic development. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 17: 326-35. PMID 22390626 DOI: 10.1111/J.1365-2443.2012.01591.X  0.748
2012 Ip JP, Shi L, Chen Y, Itoh Y, Fu WY, Betz A, Yung WH, Gotoh Y, Fu AK, Ip NY. α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2. Nature Neuroscience. 15: 39-47. PMID 22138645 DOI: 10.1038/Nn.2972  0.761
2010 Hirabayashi Y, Gotoh Y. Epigenetic control of neural precursor cell fate during development. Nature Reviews. Neuroscience. 11: 377-88. PMID 20485363 DOI: 10.1038/Nrn2810  0.763
2010 Kuwahara A, Hirabayashi Y, Knoepfler PS, Taketo MM, Sakai J, Kodama T, Gotoh Y. Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development (Cambridge, England). 137: 1035-44. PMID 20215343 DOI: 10.1242/Dev.046417  0.748
2010 Miyata T, Kawaguchi D, Kawaguchi A, Gotoh Y. Mechanisms that regulate the number of neurons during mouse neocortical development. Current Opinion in Neurobiology. 20: 22-8. PMID 20138502 DOI: 10.1016/J.Conb.2010.01.001  0.426
2010 Hirabayashi Y, Suzki N, Gotoh Y. Temporal regulation of neural stem cell fate in the developing mouse neocortex Neuroscience Research. 68: e3. DOI: 10.1016/J.Neures.2010.07.002  0.764
2009 Hirabayashi Y, Suzki N, Tsuboi M, Endo TA, Toyoda T, Shinga J, Koseki H, Vidal M, Gotoh Y. Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron. 63: 600-13. PMID 19755104 DOI: 10.1016/J.Neuron.2009.08.021  0.812
2009 Oishia K, Watatani K, Itoh Y, Okano H, Guillemot F, Nakajima K, Gotoh Y. Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1 Proceedings of the National Academy of Sciences of the United States of America. 106: 13064-13069. PMID 19549840 DOI: 10.1073/Pnas.0808400106  0.484
2008 Kawaguchi D, Yoshimatsu T, Hozumi K, Gotoh Y. Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon. Development (Cambridge, England). 135: 3849-58. PMID 18997111 DOI: 10.1242/Dev.024570  0.531
2008 Higuchi M, Onishi K, Kikuchi C, Gotoh Y. Scaffolding function of PAK in the PDK1-Akt pathway. Nature Cell Biology. 10: 1356-64. PMID 18931661 DOI: 10.1038/Ncb1795  0.316
2008 Mori Y, Higuchi M, Hirabayashi Y, Fukuda M, Gotoh Y. JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release. The Embo Journal. 27: 76-87. PMID 18046461 DOI: 10.1038/Sj.Emboj.7601935  0.681
2007 Adachi K, Mirzadeh Z, Sakaguchi M, Yamashita T, Nikolcheva T, Gotoh Y, Peltz G, Gong L, Kawase T, Alvarez-Buylla A, Okano H, Sawamoto K. Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells (Dayton, Ohio). 25: 2827-36. PMID 17673525 DOI: 10.1634/Stemcells.2007-0177  0.452
2007 Ura S, Nishina H, Gotoh Y, Katada T. Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis. Molecular and Cellular Biology. 27: 5514-22. PMID 17548476 DOI: 10.1128/Mcb.00199-07  0.366
2007 Onishi K, Higuchi M, Asakura T, Masuyama N, Gotoh Y. The PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 12: 535-46. PMID 17397400 DOI: 10.1111/J.1365-2443.2007.01071.X  0.353
2007 Hayakawa-Yano Y, Nishida K, Fukami S, Gotoh Y, Hirano T, Nakagawa T, Shimazaki T, Okano H. Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord. Stem Cells (Dayton, Ohio). 25: 1410-22. PMID 17332510 DOI: 10.1634/Stemcells.2006-0584  0.368
2007 Itoh Y, Masuyama N, Nakayama K, Nakayama KI, Gotoh Y. The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex. The Journal of Biological Chemistry. 282: 390-6. PMID 17092932 DOI: 10.1074/Jbc.M609944200  0.419
2007 Yoshizaki H, Mochizuki N, Gotoh Y, Matsuda M. Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation. Molecular Biology of the Cell. 18: 119-28. PMID 17079732 DOI: 10.1091/Mbc.E06-05-0467  0.314
2006 Yoshimatsu T, Kawaguchi D, Oishi K, Takeda K, Akira S, Masuyama N, Gotoh Y. Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development (Cambridge, England). 133: 2553-63. PMID 16728475 DOI: 10.1242/Dev.02419  0.493
2005 Sunayama J, Tsuruta F, Masuyama N, Gotoh Y. JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3. The Journal of Cell Biology. 170: 295-304. PMID 16009721 DOI: 10.1083/Jcb.200409117  0.327
2005 Takada T, Suzuki H, Gotoh Y, Sugiyama Y. Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of Akt in polarized cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 905-9. PMID 15843490 DOI: 10.1124/Dmd.104.003228  0.37
2005 Hirabayashi Y, Gotoh Y. Stage-dependent fate determination of neural precursor cells in mouse forebrain. Neuroscience Research. 51: 331-6. PMID 15740796 DOI: 10.1016/J.Neures.2005.01.004  0.753
2004 Mori Y, Higuchi M, Masuyama N, Gotoh Y. Adenosine A2A receptor facilitates calcium-dependent protein secretion through the activation of protein kinase A and phosphatidylinositol-3 kinase in PC12 cells. Cell Structure and Function. 29: 101-10. PMID 15665505 DOI: 10.1247/Csf.29.101  0.311
2004 Oishi K, Kamakura S, Isazawa Y, Yoshimatsu T, Kuida K, Nakafuku M, Masuyama N, Gotoh Y. Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis. Developmental Biology. 276: 172-84. PMID 15531372 DOI: 10.1016/J.Ydbio.2004.08.039  0.411
2004 Kamakura S, Oishi K, Yoshimatsu T, Nakafuku M, Masuyama N, Gotoh Y. Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nature Cell Biology. 6: 547-54. PMID 15156153 DOI: 10.1038/Ncb1138  0.393
2004 Hirabayashi Y, Itoh Y, Tabata H, Nakajima K, Akiyama T, Masuyama N, Gotoh Y. The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development (Cambridge, England). 131: 2791-801. PMID 15142975 DOI: 10.1242/Dev.01165  0.765
2004 Miyagi S, Saito T, Mizutani K, Masuyama N, Gotoh Y, Iwama A, Nakauchi H, Masui S, Niwa H, Nishimoto M, Muramatsu M, Okuda A. The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells. Molecular and Cellular Biology. 24: 4207-20. PMID 15121842 DOI: 10.1128/Mcb.24.10.4207-4220.2004  0.485
2004 Tsuruta F, Sunayama J, Mori Y, Hattori S, Shimizu S, Tsujimoto Y, Yoshioka K, Masuyama N, Gotoh Y. JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins. The Embo Journal. 23: 1889-99. PMID 15071501 DOI: 10.1038/Sj.Emboj.7600194  0.307
2003 Higuchi M, Onishi K, Masuyama N, Gotoh Y. The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 8: 657-69. PMID 12875651 DOI: 10.1046/J.1365-2443.2003.00663.X  0.318
2003 Sakoda H, Gotoh Y, Katagiri H, Kurokawa M, Ono H, Onishi Y, Anai M, Ogihara T, Fujishiro M, Fukushima Y, Abe M, Shojima N, Kikuchi M, Oka Y, Hirai H, et al. Differing roles of Akt and serum- and glucocorticoid-regulated kinase in glucose metabolism, DNA synthesis, and oncogenic activity. The Journal of Biological Chemistry. 278: 25802-7. PMID 12734207 DOI: 10.1074/Jbc.M301127200  0.328
2003 Suzawa M, Takada I, Yanagisawa J, Ohtake F, Ogawa S, Yamauchi T, Kadowaki T, Takeuchi Y, Shibuya H, Gotoh Y, Matsumoto K, Kato S. Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nature Cell Biology. 5: 224-30. PMID 12598905 DOI: 10.1038/Ncb942  0.338
2002 Shinohara M, Terada Y, Iwamatsu A, Shinohara A, Mochizuki N, Higuchi M, Gotoh Y, Ihara S, Nagata S, Itoh H, Fukui Y, Jessberger R. SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. Nature. 416: 759-63. PMID 11961559 DOI: 10.1038/416759A  0.301
2002 Ogawara Y, Kishishita S, Obata T, Isazawa Y, Suzuki T, Tanaka K, Masuyama N, Gotoh Y. Akt enhances Mdm2-mediated ubiquitination and degradation of p53. The Journal of Biological Chemistry. 277: 21843-50. PMID 11923280 DOI: 10.1074/Jbc.M109745200  0.315
2002 Tsuruta F, Masuyama N, Gotoh Y. The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria. The Journal of Biological Chemistry. 277: 14040-7. PMID 11842081 DOI: 10.1074/Jbc.M108975200  0.317
2002 Higuchi M, Masuyama N, Fukui Y, Suzuki A, Gotoh Y. Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells. Current Biology : Cb. 11: 1958-62. PMID 11747822 DOI: 10.1016/S0960-9822(01)00599-1  0.392
2001 Morishima Y, Gotoh Y, Zieg J, Barrett T, Takano H, Flavell R, Davis RJ, Shirasaki Y, Greenberg ME. Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7551-60. PMID 11567045 DOI: 10.1523/Jneurosci.21-19-07551.2001  0.515
2001 Ura S, Masuyama N, Graves JD, Gotoh Y. Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation. Proceedings of the National Academy of Sciences of the United States of America. 98: 10148-10153. PMID 11517310 DOI: 10.1073/Pnas.181161698  0.306
2001 Masuyama N, Oishi K, Mori Y, Ueno T, Takahama Y, Gotoh Y. Akt Inhibits the Orphan Nuclear Receptor Nur77 and T-cell Apoptosis Journal of Biological Chemistry. 276: 32799-32805. PMID 11438550 DOI: 10.1074/Jbc.M105431200  0.344
2001 Morishima Y, Gotoh Y, Zieg J, Barrett T, Takano H, Flavell R, Davis RJ, Shirasaki Y, Greenberg ME. β-Amyloid Induces Neuronal Apoptosis Via a Mechanism that Involves the c-Jun N-Terminal Kinase Pathway and the Induction of Fas Ligand The Journal of Neuroscience. 21: 7551-7560. DOI: 10.1523/JNEUROSCI.21-19-07551.2001  0.441
1999 Kawasaki H, Fujii H, Gotoh Y, Morooka T, Shimohama S, Nishida E, Hirano T. Requirement for mitogen-activated protein kinase in cerebellar long term depression. The Journal of Biological Chemistry. 274: 13498-502. PMID 10224117 DOI: 10.1074/Jbc.274.19.13498  0.428
1998 Graves JD, Gotoh Y, Draves KE, Ambrose D, Han DK, Wright M, Chernoff J, Clark EA, Krebs EG. Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1. The Embo Journal. 17: 2224-34. PMID 9545236 DOI: 10.1093/Emboj/17.8.2224  0.314
1998 Shibuya H, Iwata H, Masuyama N, Gotoh Y, Yamaguchi K, Irie K, Matsumoto K, Nishida E, Ueno N. Role of TAK1 and TAB1 in BMP signaling in early Xenopus development. The Embo Journal. 17: 1019-28. PMID 9463380 DOI: 10.1093/Emboj/17.4.1019  0.362
1997 Fukuda M, Gotoh I, Adachi M, Gotoh Y, Nishida E. A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase. The Journal of Biological Chemistry. 272: 32642-8. PMID 9405481 DOI: 10.1074/Jbc.272.51.32642  0.352
1997 Moriguchi T, Toyoshima F, Masuyama N, Hanafusa H, Gotoh Y, Nishida E. A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses. The Embo Journal. 16: 7045-53. PMID 9384583 DOI: 10.1093/Emboj/16.23.7045  0.333
1997 Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91: 231-41. PMID 9346240 DOI: 10.1016/S0092-8674(00)80405-5  0.693
1997 Kawasaki H, Morooka T, Shimohama S, Kimura J, Hirano T, Gotoh Y, Nishida E. Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. The Journal of Biological Chemistry. 272: 18518-21. PMID 9228012 DOI: 10.1074/Jbc.272.30.18518  0.354
1997 Fukuda M, Gotoh Y, Nishida E. Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. The Embo Journal. 16: 1901-8. PMID 9155016 DOI: 10.1093/Emboj/16.8.1901  0.335
1997 Shirakabe K, Yamaguchi K, Shibuya H, Irie K, Matsuda S, Moriguchi T, Gotoh Y, Matsumoto K, Nishida E. TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase. The Journal of Biological Chemistry. 272: 8141-4. PMID 9079627 DOI: 10.1074/Jbc.272.13.8141  0.324
1997 Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, Gotoh Y. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science (New York, N.Y.). 275: 90-4. PMID 8974401 DOI: 10.1126/Science.275.5296.90  0.314
1996 Kamata H, Tanaka C, Yagisawa H, Matsuda S, Gotoh Y, Nishida E, Hirata H. Suppression of nerve growth factor-induced neuronal differentiation of PC12 cells. N-acetylcysteine uncouples the signal transduction from ras to the mitogen-activated protein kinase cascade. The Journal of Biological Chemistry. 271: 33018-25. PMID 8955147 DOI: 10.1074/Jbc.271.51.33018  0.436
1996 Toda T, Dhut S, Superti-Furga G, Gotoh Y, Nishida E, Sugiura R, Kuno T. The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway. Molecular and Cellular Biology. 16: 6752-64. PMID 8943330 DOI: 10.1128/Mcb.16.12.6752  0.37
1996 Kawasaki H, Moriguchi T, Matsuda S, Li HZ, Nakamura S, Shimohama S, Kimura J, Gotoh Y, Nishida E. Ras-dependent and Ras-independent activation pathways for the stress-activated-protein-kinase cascade. European Journal of Biochemistry / Febs. 241: 315-21. PMID 8917425 DOI: 10.1111/J.1432-1033.1996.00315.X  0.315
1996 Moriguchi T, Toyoshima F, Gotoh Y, Iwamatsu A, Irie K, Mori E, Kuroyanagi N, Hagiwara M, Matsumoto K, Nishida E. Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2. The Journal of Biological Chemistry. 271: 26981-8. PMID 8900184 DOI: 10.1074/Jbc.271.43.26981  0.348
1996 Moriguchi T, Gotoh Y, Nishida E. Roles of the MAP kinase cascade in vertebrates. Advances in Pharmacology (San Diego, Calif.). 36: 121-37. PMID 8783557 DOI: 10.1016/S1054-3589(08)60579-7  0.313
1996 Gotoh Y, Nishida E. Signals for mesoderm induction. Roles of fibroblast growth factor (FGF)/mitogen-activated protein kinase (MAPK) pathway. Biochimica Et Biophysica Acta. 1288: F1-7. PMID 8764836 DOI: 10.1016/0304-419X(96)00009-1  0.327
1996 Moriguchi T, Kuroyanagi N, Yamaguchi K, Gotoh Y, Irie K, Kano T, Shirakabe K, Muro Y, Shibuya H, Matsumoto K, Nishida E, Hagiwara M. A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. The Journal of Biological Chemistry. 271: 13675-9. PMID 8663074 DOI: 10.1074/Jbc.271.23.13675  0.33
1996 Shibuya H, Yamaguchi K, Shirakabe K, Tonegawa A, Gotoh Y, Ueno N, Irie K, Nishida E, Matsumoto K. TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science (New York, N.Y.). 272: 1179-82. PMID 8638164 DOI: 10.1126/Science.272.5265.1179  0.301
1996 Kosako H, Gotoh Y, Nishida E. Multiple roles of the mitogen-activated protein kinase kinase/mitogen- activated protein kinase cascade in Xenopus laevis Development Growth and Differentiation. 38: 577-582. DOI: 10.1046/J.1440-169X.1996.T01-5-00001.X  0.347
1996 Kamata H, Tanaka C, Yagisawa H, Matsuda S, Gotoh Y, Nishida E, Hirata H. INVOLVEMENT OF CELLULAR REDOX STATE IN CELL SURVIVAL AND NEURONAL DIFFERENTIATION IN PC12 CELLS Biochemical Society Transactions. 24: 541S-541S. DOI: 10.1042/Bst024541Sb  0.437
1995 Gotoh Y, Nishida E. The MAP kinase cascade: its role in Xenopus oocytes, eggs and embryos. Progress in Cell Cycle Research. 1: 287-97. PMID 9552371 DOI: 10.1007/978-1-4615-1809-9_23  0.332
1995 Gotoh Y, Nishida E. Activation mechanism and function of the MAP kinase cascade. Molecular Reproduction and Development. 42: 486-92. PMID 8607980 DOI: 10.1002/Mrd.1080420417  0.367
1995 Moriguchi T, Gotoh Y, Nishida E. Activation of two isoforms of mitogen-activated protein kinase kinase in response to epidermal growth factor and nerve growth factor. European Journal of Biochemistry / Febs. 234: 32-8. PMID 8529659 DOI: 10.1111/J.1432-1033.1995.032_C.X  0.35
1995 Gotoh Y, Masuyama N, Suzuki A, Ueno N, Nishida E. Involvement of the MAP kinase cascade in Xenopus mesoderm induction. The Embo Journal. 14: 2491-8. PMID 7781601 DOI: 10.1002/J.1460-2075.1995.Tb07246.X  0.38
1995 Moriguchi T, Kawasaki H, Matsuda S, Gotoh Y, Nishida E. Evidence for multiple activators for stress-activated protein kinase/c-Jun amino-terminal kinases. Existence of novel activators. The Journal of Biological Chemistry. 270: 12969-72. PMID 7768885 DOI: 10.1074/Jbc.270.22.12969  0.3
1995 Matsuda S, Kawasaki H, Moriguchi T, Gotoh Y, Nishida E. Activation of protein kinase cascades by osmotic shock. The Journal of Biological Chemistry. 270: 12781-6. PMID 7759532 DOI: 10.1074/Jbc.270.21.12781  0.321
1995 Gotoh Y, Masuyama N, Dell K, Shirakabe K, Nishida E. Initiation of Xenopus oocyte maturation by activation of the mitogen-activated protein kinase cascade. The Journal of Biological Chemistry. 270: 25898-904. PMID 7592777 DOI: 10.1074/Jbc.270.43.25898  0.332
1995 Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H, Masushige S, Gotoh Y, Nishida E, Kawashima H, Metzger D, Chambon P. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (New York, N.Y.). 270: 1491-4. PMID 7491495 DOI: 10.1126/Science.270.5241.1491  0.321
1994 Mizoguchi T, Gotoh Y, Nishida E, Yamaguchi-Shinozaki K, Hayashida N, Iwasaki T, Kamada H, Shinozaki K. Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells. The Plant Journal : For Cell and Molecular Biology. 5: 111-22. PMID 8130795 DOI: 10.1046/J.1365-313X.1994.5010111.X  0.314
1994 Irie K, Gotoh Y, Yashar BM, Errede B, Nishida E, Matsumoto K. Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase. Science (New York, N.Y.). 265: 1716-9. PMID 8085159 DOI: 10.1126/Science.8085159  0.336
1994 Matsuda S, Gotoh Y, Nishida E. Signaling pathways mediated by the mitogen-activated protein (MAP) kinase kinase/MAP kinase cascade. Journal of Leukocyte Biology. 56: 548-53. PMID 7964162 DOI: 10.1002/Jlb.56.5.548  0.309
1993 Kosako H, Nishida E, Gotoh Y. cDNA cloning of MAP kinase kinase reveals kinase cascade pathways in yeasts to vertebrates. The Embo Journal. 12: 787-94. PMID 8440264 DOI: 10.1002/J.1460-2075.1993.Tb05713.X  0.304
1993 Gotoh Y, Nishida E, Shimanuki M, Toda T, Imai Y, Yamamoto M. Schizosaccharomyces pombe Spk1 is a tyrosine-phosphorylated protein functionally related to Xenopus mitogen-activated protein kinase. Molecular and Cellular Biology. 13: 6427-34. PMID 8413241 DOI: 10.1128/Mcb.13.10.6427  0.352
1993 Lee KS, Irie K, Gotoh Y, Watanabe Y, Araki H, Nishida E, Matsumoto K, Levin DE. A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C. Molecular and Cellular Biology. 13: 3067-75. PMID 8386319 DOI: 10.1128/Mcb.13.5.3067  0.333
1992 Nishida E, Gotoh Y. Mitogen-activated protein kinase and cytoskeleton in mitogenic signal transduction International Review of Cytology. 138: 211-238. PMID 1333452 DOI: 10.1016/S0074-7696(08)61589-2  0.346
1992 Shiina N, Moriguchi T, Ohta K, Gotoh Y, Nishida E. Regulation of a major microtubule-associated protein by MPF and MAP kinase. The Embo Journal. 11: 3977-84. PMID 1327753 DOI: 10.1002/J.1460-2075.1992.Tb05491.X  0.308
1991 Gotoh Y, Nishida E, Yamashita T, Hoshi M, Kawakami M, Sakai H. Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells. European Journal of Biochemistry. 193: 661-9. PMID 2174361 DOI: 10.1111/J.1432-1033.1990.Tb19384.X  0.318
1991 Gotoh Y, Nishida E, Matsuda S, Shiina N, Kosako H, Shiokawa K, Akiyama T, Ohta K, Sakai H. In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase. Nature. 349: 251-4. PMID 1702878 DOI: 10.1038/349251A0  0.314
1990 Hoshi M, Nishida E, Inagaki M, Gotoh Y, Sakai H. Activation of a serine/threonine kinase that phosphorylates microtubule-associated protein 1B in vitro by growth factors and phorbol esters in quiescent rat fibroblastic cells. European Journal of Biochemistry. 193: 513-9. PMID 2226468 DOI: 10.1111/J.1432-1033.1990.Tb19366.X  0.325
1990 Gotoh Y, Nishida E, Sakai H. Okadaic acid activates microtubule-associated protein kinase in quiescent fibroblastic cells European Journal of Biochemistry. 193: 671-674. PMID 2174362 DOI: 10.1111/J.1432-1033.1990.Tb19385.X  0.323
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