| Year |
Citation |
Score |
| 2022 |
He Y, Kim J, Tacconi C, Moody J, Dieterich LC, Anzengruber F, Maul JT, Gousopoulos E, Restivo G, Levesque MP, Lindenblatt N, Shin JW, Hon CC, Detmar M. Mediators of capillary-to-venule conversion in the chronic inflammatory skin disease psoriasis. The Journal of Investigative Dermatology. PMID 35777499 DOI: 10.1016/j.jid.2022.05.1089 |
0.329 |
|
| 2022 |
Dieterich LC, Tacconi C, Ducoli L, Detmar M. Lymphatic vessels in cancer. Physiological Reviews. PMID 35771983 DOI: 10.1152/physrev.00039.2021 |
0.307 |
|
| 2022 |
Yoon SY, Detmar M. Sostdc1 Secreted from Cutaneous Lymphatic Vessels Acts as a Paracrine Factor for Hair Follicle Growth. Current Issues in Molecular Biology. 44: 2167-2174. PMID 35678675 DOI: 10.3390/cimb44050146 |
0.375 |
|
| 2022 |
He Y, Tacconi C, Dieterich LC, Kim J, Restivo G, Gousopoulos E, Lindenblatt N, Levesque MP, Claassen M, Detmar M. Novel Blood Vascular Endothelial Subtype-Specific Markers in Human Skin Unearthed by Single-Cell Transcriptomic Profiling. Cells. 11. PMID 35406678 DOI: 10.3390/cells11071111 |
0.35 |
|
| 2022 |
Liu YH, Brunner LM, Rebling J, Ben-Yehuda Greenwald M, Werner S, Detmar M, Razansky D. Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds. Theranostics. 12: 558-573. PMID 34976201 DOI: 10.7150/thno.65287 |
0.313 |
|
| 2020 |
Tacconi C, He Y, Ducoli L, Detmar M. Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells. Angiogenesis. PMID 32918672 DOI: 10.1007/S10456-020-09743-9 |
0.443 |
|
| 2020 |
Sesartić M, Ikenberg K, Yoon SY, Detmar M. Keratinocyte-Expressed Podoplanin is Dispensable for Multi-Step Skin Carcinogenesis. Cells. 9. PMID 32599908 DOI: 10.3390/Cells9061542 |
0.398 |
|
| 2020 |
Roudnicky F, Poyet C, Buser L, Saba K, Wild P, Otto VI, Detmar M. Characterization of tumor blood vasculature expression of human invasive bladder cancer by laser capture microdissection and transcriptional profiling. The American Journal of Pathology. PMID 32585158 DOI: 10.1016/J.Ajpath.2020.05.020 |
0.402 |
|
| 2020 |
Dieterich LC, Tacconi C, Menzi F, Proulx ST, Kapaklikaya K, Hamada M, Takahashi S, Detmar M. Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis. Angiogenesis. PMID 32307629 DOI: 10.1007/S10456-020-09721-1 |
0.451 |
|
| 2020 |
Fujimoto N, He Y, D'Addio M, Tacconi C, Detmar M, Dieterich LC. Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes. Plos Biology. 18: e3000704. PMID 32251437 DOI: 10.1371/Journal.Pbio.3000704 |
0.39 |
|
| 2019 |
Dieterich LC, Kapaklikaya K, Cetintas T, Proulx ST, Commerford CD, Ikenberg K, Bachmann SB, Scholl J, Detmar M. Transcriptional profiling of breast cancer-associated lymphatic vessels reveals VCAM-1 as regulator of lymphatic invasion and permeability. International Journal of Cancer. PMID 31344266 DOI: 10.1002/Ijc.32594 |
0.423 |
|
| 2019 |
Yoon SY, Dieterich LC, Karaman S, Proulx ST, Bachmann SB, Sciaroni C, Detmar M. An important role of cutaneous lymphatic vessels in coordinating and promoting anagen hair follicle growth. Plos One. 14: e0220341. PMID 31344105 DOI: 10.1371/Journal.Pone.0220341 |
0.434 |
|
| 2019 |
Yoon SY, Dieterich LC, Tacconi C, Sesartic M, He Y, Brunner L, Kwon O, Detmar M. An important role of podoplanin in hair follicle growth. Plos One. 14: e0219938. PMID 31335913 DOI: 10.1371/Journal.Pone.0219938 |
0.358 |
|
| 2019 |
Tacconi C, Ungaro F, Correale C, Arena V, Massimino L, Detmar M, Spinelli A, Carvello M, Mazzone M, Oliveira AI, Rubbino F, Garlatti V, Spanò S, Lugli E, Colombo FS, et al. Activation of the VEGFC/VEGFR3 pathway induces tumor immune escape in colorectal cancer. Cancer Research. PMID 31239267 DOI: 10.1158/0008-5472.Can-18-3657 |
0.399 |
|
| 2019 |
Bachmann SB, Gsponer D, Montoya-Zegarra JA, Schneider M, Scholkmann F, Tacconi C, Noerrelykke SF, Proulx ST, Detmar M. A Distinct Role of the Autonomic Nervous System in Modulating the Function of Lymphatic Vessels under Physiological and Tumor-Draining Conditions. Cell Reports. 27: 3305-3314.e13. PMID 31189113 DOI: 10.1016/J.Celrep.2019.05.050 |
0.367 |
|
| 2019 |
Schwager S, Detmar M. Inflammation and Lymphatic Function. Frontiers in Immunology. 10: 308. PMID 30863410 DOI: 10.3389/Fimmu.2019.00308 |
0.446 |
|
| 2019 |
Bachmann SB, Proulx ST, He Y, Ries M, Detmar M. Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo. The Journal of Physiology. PMID 30829392 DOI: 10.1113/Jp277254 |
0.386 |
|
| 2019 |
Polomska AK, Proulx ST, Brambilla D, Fehr D, Bonmarin M, Brändli S, Meboldt M, Steuer C, Vasileva T, Reinke N, Leroux JC, Detmar M. Minimally-invasive method for the point-of-care quantification of lymphatic vessel function. Jci Insight. PMID 30667371 DOI: 10.1172/Jci.Insight.126515 |
0.323 |
|
| 2019 |
Polomska A, Proulx ST, Fehr D, Bonmarin M, Leroux J, Detmar M. 1030 A minimally-invasive method for the quantification of lymphatic vessel function in the skin Journal of Investigative Dermatology. 139. DOI: 10.1016/J.Jid.2019.03.1106 |
0.331 |
|
| 2018 |
Commerford CD, Dieterich LC, He Y, Hell T, Montoya-Zegarra JA, Noerrelykke SF, Russo E, Röcken M, Detmar M. Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes. Cell Reports. 25: 3554-3563.e4. PMID 30590031 DOI: 10.1016/J.Celrep.2018.12.002 |
0.395 |
|
| 2018 |
Schwager S, Renner S, Hemmerle T, Karaman S, Proulx ST, Fetz R, Golding-Ochsenbein AM, Probst P, Halin C, Neri D, Detmar M. Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation. Jci Insight. 3. PMID 30518687 DOI: 10.1172/Jci.Insight.124850 |
0.416 |
|
| 2018 |
Montoya-Zegarra JA, Russo E, Runge P, Jadhav M, Willrodt AH, Stoma S, Nørrelykke SF, Detmar M, Halin C. AutoTube: a novel software for the automated morphometric analysis of vascular networks in tissues. Angiogenesis. PMID 30370470 DOI: 10.1007/S10456-018-9652-3 |
0.417 |
|
| 2018 |
Bachmann SB, Detmar M, Proulx ST. Visualization and Measurement of Lymphatic Function In Vivo. Methods in Molecular Biology (Clifton, N.J.). 1846: 197-211. PMID 30242761 DOI: 10.1007/978-1-4939-8712-2_13 |
0.348 |
|
| 2018 |
Ma Q, Dieterich LC, Ikenberg K, Bachmann SB, Mangana J, Proulx ST, Amann VC, Levesque MP, Dummer R, Baluk P, McDonald DM, Detmar M. Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread. Science Advances. 4: eaat4758. PMID 30101193 DOI: 10.1126/Sciadv.Aat4758 |
0.406 |
|
| 2018 |
Brown M, Johnson LA, Leone DA, Majek P, Vaahtomeri K, Senfter D, Bukosza N, Schachner H, Asfour G, Langer B, Hauschild R, Parapatics K, Hong YK, Bennett KL, Kain R, ... Detmar M, et al. Lymphatic exosomes promote dendritic cell migration along guidance cues. The Journal of Cell Biology. PMID 29650776 DOI: 10.1083/Jcb.201612051 |
0.406 |
|
| 2018 |
Ma Q, Dieterich LC, Detmar M. Multiple roles of lymphatic vessels in tumor progression. Current Opinion in Immunology. 53: 7-12. PMID 29605736 DOI: 10.1016/J.Coi.2018.03.018 |
0.365 |
|
| 2018 |
Roudnicky F, Yoon SY, Poghosyan S, Schwager S, Poyet C, Vella G, Bachmann SB, Karaman S, Shin JW, Otto VI, Detmar M. Alternative transcription of a shorter, non-anti-angiogenic thrombospondin-2 variant in cancer-associated blood vessels. Oncogene. PMID 29467494 DOI: 10.1038/S41388-018-0129-Z |
0.467 |
|
| 2018 |
Schwager S, Zgraggen S, Hemmerle T, Proulx S, Halin C, Neri D, Detmar M. 936 Targeted activation of lymphatic vessels in inflamed skin potently inhibits skin inflammation Journal of Investigative Dermatology. 138. DOI: 10.1016/J.Jid.2018.03.948 |
0.334 |
|
| 2017 |
Ma Q, Ineichen BV, Detmar M, Proulx ST. Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice. Nature Communications. 8: 1434. PMID 29127332 DOI: 10.1038/S41467-017-01484-6 |
0.319 |
|
| 2017 |
Dieterich LC, Ducoli L, Shin JW, Detmar M. Distinct transcriptional responses of lymphatic endothelial cells to VEGFR-3 and VEGFR-2 stimulation. Scientific Data. 4: 170106. PMID 28850122 DOI: 10.1038/Sdata.2017.106 |
0.463 |
|
| 2017 |
Gousopoulos E, Proulx ST, Bachmann SB, Dieterich LC, Scholl J, Karaman S, Bianchi R, Detmar M. An Important Role of VEGF-C in Promoting Lymphedema Development. The Journal of Investigative Dermatology. PMID 28526302 DOI: 10.1016/J.Jid.2017.04.033 |
0.483 |
|
| 2017 |
Roudnicky F, Dieterich LC, Poyet C, Buser L, Wild P, Tang D, Camenzind P, Hsien Ho C, Otto VI, Detmar M. High expression of insulin receptor on tumor-associated blood vessels in invasive bladder cancer predicts poor overall and progression-free survival. The Journal of Pathology. PMID 28295307 DOI: 10.1002/Path.4892 |
0.412 |
|
| 2017 |
Dieterich LC, Ikenberg K, Cetintas T, Kapaklikaya K, Hutmacher C, Detmar M. Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation. Frontiers in Immunology. 8: 66. PMID 28217128 DOI: 10.3389/Fimmu.2017.00066 |
0.404 |
|
| 2017 |
Teijeira A, Hunter MC, Russo E, Proulx ST, Frei T, Debes GF, Coles M, Melero I, Detmar M, Rouzaut A, Halin C. T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. Cell Reports. 18: 857-865. PMID 28122237 DOI: 10.1016/J.Celrep.2016.12.078 |
0.37 |
|
| 2017 |
Proulx ST, Ma Q, Andina D, Leroux JC, Detmar M. Quantitative measurement of lymphatic function in mice by noninvasive near-infrared imaging of a peripheral vein. Jci Insight. 2: e90861. PMID 28097238 DOI: 10.1172/Jci.Insight.90861 |
0.34 |
|
| 2017 |
Yoon S, Dieterich L, Karaman S, Proulx S, Bachmann S, Sciaroni C, Detmar M. 845 Dermal lymphatic vessels promote hair follicle growth via the BMP inhibitor Sostdc1 Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.02.871 |
0.348 |
|
| 2016 |
Cui J, Hollmén M, Li L, Chen Y, Proulx ST, Reker D, Schneider G, Detmar M. New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate. Oncotarget. PMID 27894093 DOI: 10.18632/Oncotarget.13537 |
0.658 |
|
| 2016 |
Bianchi R, Russo E, Bachmann SB, Proulx ST, Sesartic M, Smaadahl N, Watson SP, Buckley CD, Halin C, Detmar M. Postnatal Deletion of Podoplanin in Lymphatic Endothelium Results in Blood Filling of the Lymphatic System and Impairs Dendritic Cell Migration to Lymph Nodes. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27810998 DOI: 10.1161/Atvbaha.116.308020 |
0.404 |
|
| 2016 |
Gousopoulos E, Proulx ST, Bachmann SB, Scholl J, Dionyssiou D, Demiri E, Halin C, Dieterich LC, Detmar M. Regulatory T cell transfer ameliorates lymphedema and promotes lymphatic vessel function. Jci Insight. 1: e89081. PMID 27734032 DOI: 10.1172/Jci.Insight.89081 |
0.368 |
|
| 2016 |
Docherty JR, Steinhoff M, Lorton D, Detmar M, Schäfer G, Holmes A, Di Nardo A. Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy. Advances in Therapy. PMID 27562835 DOI: 10.1007/S12325-016-0404-8 |
0.334 |
|
| 2016 |
Karaman S, Hollmén M, Yoon SY, Alkan HF, Alitalo K, Wolfrum C, Detmar M. Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice. Scientific Reports. 6: 31566. PMID 27511834 DOI: 10.1038/Srep31566 |
0.325 |
|
| 2016 |
Ochsenbein AM, Karaman S, Proulx ST, Goldmann R, Chittazhathu J, Dasargyri A, Chong C, Leroux JC, Stanley ER, Detmar M. Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling. Angiogenesis. PMID 27464987 DOI: 10.1007/S10456-016-9523-8 |
0.463 |
|
| 2016 |
Gousopoulos E, Proulx ST, Scholl J, Uecker M, Detmar M. Prominent Lymphatic Vessel Hyperplasia with Progressive Dysfunction and Distinct Immune Cell Infiltration in Lymphedema. The American Journal of Pathology. 186: 2193-203. PMID 27315777 DOI: 10.1016/J.Ajpath.2016.04.006 |
0.408 |
|
| 2016 |
Christiansen AJ, Dieterich LC, Ohs I, Bachmann SB, Bianchi R, Proulx ST, Hollmén M, Aebischer D, Detmar M. Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation. Oncotarget. 7: 39421-39435. PMID 27270646 DOI: 10.18632/Oncotarget.9820 |
0.455 |
|
| 2016 |
Klein S, Dieterich LC, Mathelier A, Chong C, Sliwa-Primorac A, Hong YK, Shin JW, Lizio M, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E, Carninci P, ... ... Detmar M, et al. DeepCAGE transcriptomics identify HOXD10 as transcription factor regulating lymphatic endothelial responses to VEGF-C. Journal of Cell Science. PMID 27199372 DOI: 10.1242/Jcs.186767 |
0.442 |
|
| 2016 |
Hollmén M, Karaman S, Schwager S, Lisibach A, Christiansen AJ, Maksimow M, Varga Z, Jalkanen S, Detmar M. G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer. Oncoimmunology. 5: e1115177. PMID 27141367 DOI: 10.1080/2162402X.2015.1115177 |
0.33 |
|
| 2016 |
Nishida-Fukuda H, Araki R, Shudou M, Okazaki H, Tomono Y, Nakayama H, Fukuda S, Sakaue T, Shirakata Y, Sayama K, Hashimoto K, Detmar M, Higashiyama S, Hirakawa S. Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) is induced by VEGF-A. The Journal of Biological Chemistry. PMID 26966180 DOI: 10.1074/Jbc.M115.683201 |
0.497 |
|
| 2016 |
Chong C, Scholkmann F, Bachmann SB, Luciani P, Leroux JC, Detmar M, Proulx ST. In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging. Scientific Reports. 6: 22930. PMID 26960708 DOI: 10.1038/Srep22930 |
0.341 |
|
| 2016 |
Ochsenbein AM, Karaman S, Proulx ST, Berchtold M, Jurisic G, Stoeckli ET, Detmar M. Endothelial cell-derived semaphorin 3A inhibits filopodia formation by blood vascular tip cells. Development (Cambridge, England). 143: 589-94. PMID 26884395 DOI: 10.1242/Dev.127670 |
0.479 |
|
| 2016 |
Brambilla D, Proulx ST, Marschalkova P, Detmar M, Leroux JC. Microneedles for the Noninvasive Structural and Functional Assessment of Dermal Lymphatic Vessels. Small (Weinheim An Der Bergstrasse, Germany). 12: 1053-61. PMID 26727610 DOI: 10.1002/Smll.201503093 |
0.316 |
|
| 2016 |
Dieterich LC, Detmar M. Tumor lymphangiogenesis and new drug development. Advanced Drug Delivery Reviews. 99: 148-60. PMID 26705849 DOI: 10.1016/J.Addr.2015.12.011 |
0.392 |
|
| 2015 |
Mitsi M, Schulz MM, Gousopoulos E, Ochsenbein AM, Detmar M, Vogel V. Walking the Line: A Fibronectin Fiber-Guided Assay to Probe Early Steps of (Lymph)angiogenesis. Plos One. 10: e0145210. PMID 26689200 DOI: 10.1371/Journal.Pone.0145210 |
0.419 |
|
| 2015 |
Dieterich LC, Klein S, Mathelier A, Sliwa-Primorac A, Ma Q, Hong YK, Shin JW, Hamada M, Lizio M, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E, Carninci P, ... ... Detmar M, et al. DeepCAGE Transcriptomics Reveal an Important Role of the Transcription Factor MAFB in the Lymphatic Endothelium. Cell Reports. PMID 26549461 DOI: 10.1016/J.Celrep.2015.10.002 |
0.411 |
|
| 2015 |
Karaman S, Buschle D, Luciani P, Leroux JC, Detmar M, Proulx ST. Decline of lymphatic vessel density and function in murine skin during aging. Angiogenesis. 18: 489-98. PMID 26260189 DOI: 10.1007/S10456-015-9479-0 |
0.33 |
|
| 2015 |
Aspelund A, Antila S, Proulx ST, Karlsen TV, Karaman S, Detmar M, Wiig H, Alitalo K. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. The Journal of Experimental Medicine. 212: 991-9. PMID 26077718 DOI: 10.1084/Jem.20142290 |
0.319 |
|
| 2015 |
Bianchi R, Teijeira A, Proulx ST, Christiansen AJ, Seidel CD, Rülicke T, Mäkinen T, Hägerling R, Halin C, Detmar M. A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research. Plos One. 10: e0122976. PMID 25849579 DOI: 10.1371/Journal.Pone.0122976 |
0.446 |
|
| 2015 |
Moalli F, Proulx ST, Schwendener R, Detmar M, Schlapbach C, Stein JV. Intravital and whole-organ imaging reveals capture of melanoma-derived antigen by lymph node subcapsular macrophages leading to widespread deposition on follicular dendritic cells. Frontiers in Immunology. 6: 114. PMID 25821451 DOI: 10.3389/Fimmu.2015.00114 |
0.374 |
|
| 2015 |
Hollmén M, Roudnicky F, Karaman S, Detmar M. Characterization of macrophage--cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer. Scientific Reports. 5: 9188. PMID 25776849 DOI: 10.1038/Srep09188 |
0.339 |
|
| 2015 |
Karaman S, Hollmén M, Robciuc MR, Alitalo A, Nurmi H, Morf B, Buschle D, Alkan HF, Ochsenbein AM, Alitalo K, Wolfrum C, Detmar M. Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet. Molecular Metabolism. 4: 93-105. PMID 25685697 DOI: 10.1016/J.Molmet.2014.11.006 |
0.313 |
|
| 2015 |
Dadras SS, Lin RJ, Razavi G, Kawakami A, Du J, Feige E, Milner DA, Loda MF, Granter SR, Detmar M, Widlund HR, Horstmann MA, Fisher DE. A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression. The American Journal of Pathology. 185: 252-65. PMID 25447045 DOI: 10.1016/J.Ajpath.2014.09.012 |
0.374 |
|
| 2014 |
Bianchi R, Fischer E, Yuen D, Ernst E, Ochsenbein AM, Chen L, Otto VI, Detmar M. Mutation of threonine 34 in mouse podoplanin-Fc reduces CLEC-2 binding and toxicity in vivo while retaining antilymphangiogenic activity. The Journal of Biological Chemistry. 289: 21016-27. PMID 24907275 DOI: 10.1074/Jbc.M114.550525 |
0.371 |
|
| 2014 |
Blum KS, Karaman S, Proulx ST, Ochsenbein AM, Luciani P, Leroux JC, Wolfrum C, Detmar M. Chronic high-fat diet impairs collecting lymphatic vessel function in mice. Plos One. 9: e94713. PMID 24714646 DOI: 10.1371/Journal.Pone.0094713 |
0.38 |
|
| 2014 |
Zgraggen S, Huggenberger R, Kerl K, Detmar M. An important role of the SDF-1/CXCR4 axis in chronic skin inflammation. Plos One. 9: e93665. PMID 24695674 DOI: 10.1371/Journal.Pone.0093665 |
0.412 |
|
| 2014 |
Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, ... ... Detmar M, et al. A promoter-level mammalian expression atlas. Nature. 507: 462-70. PMID 24670764 DOI: 10.1038/Nature13182 |
0.319 |
|
| 2014 |
Karaman S, Detmar M. Mechanisms of lymphatic metastasis. The Journal of Clinical Investigation. 124: 922-8. PMID 24590277 DOI: 10.1172/Jci71606 |
0.417 |
|
| 2014 |
Hirakawa S, Detmar M, Karaman S. Lymphatics in nanophysiology. Advanced Drug Delivery Reviews. 74: 12-8. PMID 24524932 DOI: 10.1016/J.Addr.2014.01.011 |
0.406 |
|
| 2014 |
Kunstfeld R, Hawighorst T, Streit M, Hong YK, Nguyen L, Brown LF, Detmar M. Thrombospondin-2 overexpression in the skin of transgenic mice reduces the susceptibility to chemically induced multistep skin carcinogenesis. Journal of Dermatological Science. 74: 106-15. PMID 24507936 DOI: 10.1016/J.Jdermsci.2014.01.002 |
0.344 |
|
| 2014 |
Suzuki T, Hirakawa S, Shimauchi T, Ito T, Sakabe J, Detmar M, Tokura Y. VEGF-A promotes IL-17A-producing γδ T cell accumulation in mouse skin and serves as a chemotactic factor for plasmacytoid dendritic cells. Journal of Dermatological Science. 74: 116-24. PMID 24485663 DOI: 10.1016/J.Jdermsci.2013.12.013 |
0.357 |
|
| 2014 |
Ochsenbein AM, Karaman S, Jurisic G, Detmar M. The role of neuropilin-1/semaphorin 3A signaling in lymphatic vessel development and maturation. Advances in Anatomy, Embryology, and Cell Biology. 214: 143-52. PMID 24276892 DOI: 10.1007/978-3-7091-1646-3_11 |
0.397 |
|
| 2014 |
Dieterich LC, Seidel CD, Detmar M. Lymphatic vessels: new targets for the treatment of inflammatory diseases. Angiogenesis. 17: 359-71. PMID 24212981 DOI: 10.1007/S10456-013-9406-1 |
0.419 |
|
| 2013 |
Valtcheva N, Primorac A, Jurisic G, Hollmén M, Detmar M. The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42. The Journal of Biological Chemistry. 288: 35736-48. PMID 24178298 DOI: 10.1074/Jbc.M113.512954 |
0.452 |
|
| 2013 |
Rodrigues T, Kudoh T, Roudnicky F, Lim YF, Lin YC, Koch CP, Seno M, Detmar M, Schneider G. Steering target selectivity and potency by fragment-based de novo drug design. Angewandte Chemie (International Ed. in English). 52: 10006-9. PMID 24030898 DOI: 10.1002/Anie.201304847 |
0.313 |
|
| 2013 |
Jurisic G, Sundberg JP, Detmar M. Blockade of VEGF receptor-3 aggravates inflammatory bowel disease and lymphatic vessel enlargement. Inflammatory Bowel Diseases. 19: 1983-9. PMID 23835443 DOI: 10.1097/Mib.0B013E31829292F7 |
0.409 |
|
| 2013 |
Marino D, Angehrn Y, Klein S, Riccardi S, Baenziger-Tobler N, Otto VI, Pittelkow M, Detmar M. Activation of the epidermal growth factor receptor promotes lymphangiogenesis in the skin. Journal of Dermatological Science. 71: 184-94. PMID 23706492 DOI: 10.1016/J.Jdermsci.2013.04.024 |
0.441 |
|
| 2013 |
Alitalo AK, Proulx ST, Karaman S, Aebischer D, Martino S, Jost M, Schneider N, Bry M, Detmar M. VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis. Cancer Research. 73: 4212-21. PMID 23695550 DOI: 10.1158/0008-5472.Can-12-4539 |
0.478 |
|
| 2013 |
Proulx ST, Luciani P, Dieterich LC, Karaman S, Leroux JC, Detmar M. Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 550-7. PMID 23665257 DOI: 10.1016/J.Jconrel.2013.04.027 |
0.398 |
|
| 2013 |
Blum KS, Proulx ST, Luciani P, Leroux JC, Detmar M. Dynamics of lymphatic regeneration and flow patterns after lymph node dissection. Breast Cancer Research and Treatment. 139: 81-6. PMID 23613202 DOI: 10.1007/S10549-013-2537-7 |
0.312 |
|
| 2013 |
Proulx ST, Luciani P, Christiansen A, Karaman S, Blum KS, Rinderknecht M, Leroux JC, Detmar M. Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis. Biomaterials. 34: 5128-37. PMID 23566803 DOI: 10.1016/J.Biomaterials.2013.03.034 |
0.367 |
|
| 2013 |
Proulx ST, Detmar M. Molecular mechanisms and imaging of lymphatic metastasis. Experimental Cell Research. 319: 1611-7. PMID 23499738 DOI: 10.1016/J.Yexcr.2013.03.009 |
0.334 |
|
| 2013 |
Zgraggen S, Ochsenbein AM, Detmar M. An important role of blood and lymphatic vessels in inflammation and allergy. Journal of Allergy. 2013: 672381. PMID 23431319 DOI: 10.1155/2013/672381 |
0.456 |
|
| 2013 |
Proulx ST, Luciani P, Alitalo A, Mumprecht V, Christiansen AJ, Huggenberger R, Leroux JC, Detmar M. Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo. Angiogenesis. 16: 525-40. PMID 23325334 DOI: 10.1007/S10456-013-9332-2 |
0.46 |
|
| 2013 |
Roudnicky F, Poyet C, Wild P, Krampitz S, Negrini F, Huggenberger R, Rogler A, Stöhr R, Hartmann A, Provenzano M, Otto VI, Detmar M. Endocan is upregulated on tumor vessels in invasive bladder cancer where it mediates VEGF-A-induced angiogenesis. Cancer Research. 73: 1097-106. PMID 23243026 DOI: 10.1158/0008-5472.Can-12-1855 |
0.429 |
|
| 2013 |
Roudnicky F, Poyet C, Wild PJ, Krampitz S, Negrini F, Huggenberger R, Rogler A, Stöhr R, Hartmann A, Provenzano M, Otto VI, Detmar M. Abstract 3893: Endocan is upregulated on tumor vessels in invasive bladder cancer and mediates VEGF-A-induced angiogenesis. Cancer Research. 73: 3893-3893. DOI: 10.1158/1538-7445.Am2013-3893 |
0.48 |
|
| 2013 |
Poyet C, Roudnicky F, Wild P, Krampitz S, Negrini F, Huggenberger R, Rogler A, Hartmann A, Sulser T, Provenzano M, Otto VI, Detmar M. 1124 Endocan Is Upregulated On Tumor Vessels In Muscle-Invasive Bladder Cancer And Mediates Vegf-A Induced Angiogenesis The Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.739 |
0.406 |
|
| 2012 |
Kanitz A, Imig J, Dziunycz PJ, Primorac A, Galgano A, Hofbauer GF, Gerber AP, Detmar M. The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma. Plos One. 7: e49568. PMID 23166713 DOI: 10.1371/Journal.Pone.0049568 |
0.356 |
|
| 2012 |
Liersch R, Hirakawa S, Berdel WE, Mesters RM, Detmar M. Induced lymphatic sinus hyperplasia in sentinel lymph nodes by VEGF-C as the earliest premetastatic indicator. International Journal of Oncology. 41: 2073-8. PMID 23076721 DOI: 10.3892/Ijo.2012.1665 |
0.384 |
|
| 2012 |
Schulz MM, Reisen F, Zgraggen S, Fischer S, Yuen D, Kang GJ, Chen L, Schneider G, Detmar M. Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 109: E2665-74. PMID 22949700 DOI: 10.1073/Pnas.1206036109 |
0.339 |
|
| 2012 |
Liersch R, Shin JW, Bayer M, Schwöppe C, Schliemann C, Berdel WE, Mesters R, Detmar M. Analysis of a novel highly metastatic melanoma cell line identifies osteopontin as a new lymphangiogenic factor. International Journal of Oncology. 41: 1455-63. PMID 22797548 DOI: 10.3892/Ijo.2012.1548 |
0.415 |
|
| 2012 |
Jurisic G, Maby-El Hajjami H, Karaman S, Ochsenbein AM, Alitalo A, Siddiqui SS, Ochoa Pereira C, Petrova TV, Detmar M. An unexpected role of semaphorin3a-neuropilin-1 signaling in lymphatic vessel maturation and valve formation. Circulation Research. 111: 426-36. PMID 22723300 DOI: 10.1161/Circresaha.112.269399 |
0.352 |
|
| 2012 |
Duong T, Proulx ST, Luciani P, Leroux JC, Detmar M, Koopman P, Francois M. Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer Research. 72: 3105-14. PMID 22523034 DOI: 10.1158/0008-5472.Can-11-4026 |
0.391 |
|
| 2012 |
Mumprecht V, Roudnicky F, Detmar M. Inflammation-induced lymph node lymphangiogenesis is reversible. The American Journal of Pathology. 180: 874-9. PMID 22200615 DOI: 10.1016/J.Ajpath.2011.11.010 |
0.343 |
|
| 2012 |
Alitalo A, Detmar M. Interaction of tumor cells and lymphatic vessels in cancer progression Oncogene. 31: 4499-4508. PMID 22179834 DOI: 10.1038/Onc.2011.602 |
0.513 |
|
| 2012 |
Proulx ST, Detmar M. Watching lymphatic vessels grow by making them glow. Cell Research. 22: 12-3. PMID 22124234 DOI: 10.1038/Cr.2011.191 |
0.386 |
|
| 2011 |
Christiansen A, Detmar M. Lymphangiogenesis and cancer. Genes & Cancer. 2: 1146-58. PMID 22866206 DOI: 10.1177/1947601911423028 |
0.404 |
|
| 2011 |
Huggenberger R, Detmar M. The cutaneous vascular system in chronic skin inflammation. The Journal of Investigative Dermatology. Symposium Proceedings. 15: 24-32. PMID 22076324 DOI: 10.1038/Jidsymp.2011.5 |
0.437 |
|
| 2011 |
Chan JY, Koon JC, Liu X, Detmar M, Yu B, Kong SK, Fung KP. Polyphyllin D, a steroidal saponin from Paris polyphylla, inhibits endothelial cell functions in vitro and angiogenesis in zebrafish embryos in vivo. Journal of Ethnopharmacology. 137: 64-9. PMID 21658438 DOI: 10.1016/J.Jep.2011.04.021 |
0.346 |
|
| 2011 |
Kerjaschki D, Bago-Horvath Z, Rudas M, Sexl V, Schneckenleithner C, Wolbank S, Bartel G, Krieger S, Kalt R, Hantusch B, Keller T, Nagy-Bojarszky K, Huttary N, Raab I, Lackner K, ... ... Detmar M, et al. Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse. The Journal of Clinical Investigation. 121: 2000-12. PMID 21540548 DOI: 10.1172/Jci44751 |
0.369 |
|
| 2011 |
Huggenberger R, Siddiqui SS, Brander D, Ullmann S, Zimmermann K, Antsiferova M, Werner S, Alitalo K, Detmar M. An important role of lymphatic vessel activation in limiting acute inflammation. Blood. 117: 4667-78. PMID 21364190 DOI: 10.1182/Blood-2010-10-316356 |
0.469 |
|
| 2011 |
Marino D, Dabouras V, Brändli AW, Detmar M. A role for all-trans-retinoic acid in the early steps of lymphatic vasculature development. Journal of Vascular Research. 48: 236-51. PMID 21099229 DOI: 10.1159/000320620 |
0.354 |
|
| 2010 |
Mumprecht V, Honer M, Vigl B, Proulx ST, Trachsel E, Kaspar M, Banziger-Tobler NE, Schibli R, Neri D, Detmar M. In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography. Cancer Research. 70: 8842-51. PMID 20978206 DOI: 10.1158/0008-5472.Can-10-0896 |
0.366 |
|
| 2010 |
Huggenberger R, Ullmann S, Proulx ST, Pytowski B, Alitalo K, Detmar M. Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation Journal of Experimental Medicine. 207: 2255-2269. PMID 20837699 DOI: 10.1084/Jem.20100559 |
0.453 |
|
| 2010 |
Proulx ST, Luciani P, Derzsi S, Rinderknecht M, Mumprecht V, Leroux JC, Detmar M. Quantitative imaging of lymphatic function with liposomal indocyanine green. Cancer Research. 70: 7053-62. PMID 20823159 DOI: 10.1158/0008-5472.Can-10-0271 |
0.403 |
|
| 2010 |
Cueni LN, Chen L, Zhang H, Marino D, Huggenberger R, Alitalo A, Bianchi R, Detmar M. Podoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skin. Blood. 116: 4376-84. PMID 20716773 DOI: 10.1182/Blood-2010-04-278564 |
0.456 |
|
| 2010 |
Rinderknecht M, Villa A, Ballmer-Hofer K, Neri D, Detmar M. Phage-derived fully human monoclonal antibody fragments to human vascular endothelial growth factor-C block its interaction with VEGF receptor-2 and 3. Plos One. 5: e11941. PMID 20689828 DOI: 10.1371/Journal.Pone.0011941 |
0.425 |
|
| 2010 |
Cueni LN, Hegyi I, Shin JW, Albinger-Hegyi A, Gruber S, Kunstfeld R, Moch H, Detmar M. Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin. The American Journal of Pathology. 177: 1004-16. PMID 20616339 DOI: 10.2353/Ajpath.2010.090703 |
0.411 |
|
| 2010 |
Jurisic G, Iolyeva M, Proulx ST, Halin C, Detmar M. Thymus cell antigen 1 (Thy1, CD90) is expressed by lymphatic vessels and mediates cell adhesion to lymphatic endothelium. Experimental Cell Research. 316: 2982-92. PMID 20599951 DOI: 10.1016/J.Yexcr.2010.06.013 |
0.508 |
|
| 2010 |
Pedrioli DM, Karpanen T, Dabouras V, Jurisic G, van de Hoek G, Shin JW, Marino D, Kälin RE, Leidel S, Cinelli P, Schulte-Merker S, Brändli AW, Detmar M. miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Molecular and Cellular Biology. 30: 3620-34. PMID 20479124 DOI: 10.1128/Mcb.00185-10 |
0.384 |
|
| 2010 |
Van de Veire S, Stalmans I, Heindryckx F, Oura H, Tijeras-Raballand A, Schmidt T, Loges S, Albrecht I, Jonckx B, Vinckier S, Van Steenkiste C, Tugues S, Rolny C, De Mol M, Dettori D, ... ... Detmar M, et al. Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Cell. 141: 178-90. PMID 20371353 DOI: 10.1016/J.Cell.2010.02.039 |
0.338 |
|
| 2010 |
Kang J, Yoo J, Lee S, Tang W, Aguilar B, Ramu S, Choi I, Otu HH, Shin JW, Dotto GP, Koh CJ, Detmar M, Hong YK. An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells. Blood. 116: 140-50. PMID 20351309 DOI: 10.1182/Blood-2009-11-252270 |
0.454 |
|
| 2010 |
Jurisic G, Sundberg JP, Bleich A, Leiter EH, Broman KW, Buechler G, Alley L, Vestweber D, Detmar M. Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease Genes and Immunity. 11: 219-231. PMID 20220769 DOI: 10.1038/Gene.2010.4 |
0.332 |
|
| 2010 |
Mumprecht V, Honer M, Vigl B, Proulx S, Trachsel E, Kaspar M, Banziger-Tobler N, Schibli R, Neri D, Detmar M. Abstract 3386:In vivoimaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography Cancer Research. 70: 3386-3386. DOI: 10.1158/1538-7445.Am10-3386 |
0.36 |
|
| 2009 |
Schonthaler HB, Huggenberger R, Wculek SK, Detmar M, Wagner EF. Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis. Proceedings of the National Academy of Sciences of the United States of America. 106: 21264-9. PMID 19995970 DOI: 10.1073/Pnas.0907550106 |
0.385 |
|
| 2009 |
Hirakawa S, Detmar M, Kerjaschki D, Nagamatsu S, Matsuo K, Tanemura A, Kamata N, Higashikawa K, Okazaki H, Kameda K, Nishida-Fukuda H, Mori H, Hanakawa Y, Sayama K, Shirakata Y, et al. Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's disease. The American Journal of Pathology. 175: 2235-48. PMID 19815713 DOI: 10.2353/Ajpath.2009.090420 |
0.43 |
|
| 2009 |
Mumprecht V, Detmar M. Lymphangiogenesis and cancer metastasis. Journal of Cellular and Molecular Medicine. 13: 1405-16. PMID 19583813 DOI: 10.1111/J.1582-4934.2009.00834.X |
0.345 |
|
| 2009 |
Kälin RE, Bänziger-Tobler NE, Detmar M, Brändli AW. An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis. Blood. 114: 1110-22. PMID 19478043 DOI: 10.1182/Blood-2009-03-211771 |
0.393 |
|
| 2009 |
Cueni LN, Detmar M. Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions. Experimental Cell Research. 315: 1715-23. PMID 19268462 DOI: 10.1016/J.Yexcr.2009.02.021 |
0.45 |
|
| 2009 |
Velasco P, Huegel R, Brasch J, Schröder JM, Weichenthal M, Stockfleth E, Schwarz T, Lawler J, Detmar M, Lange-Asschenfeldt B. The angiogenesis inhibitor thrombospondin-1 inhibits acute cutaneous hypersensitivity reactions. The Journal of Investigative Dermatology. 129: 2022-30. PMID 19194474 DOI: 10.1038/Jid.2008.447 |
0.404 |
|
| 2009 |
Doeden K, Ma Z, Narasimhan B, Swetter SM, Detmar M, Dadras SS. Lymphatic invasion in cutaneous melanoma is associated with sentinel lymph node metastasis. Journal of Cutaneous Pathology. 36: 772-80. PMID 19032379 DOI: 10.1111/J.1600-0560.2008.01166.X |
0.335 |
|
| 2009 |
Vigl B, Zgraggen C, Rehman N, Banziger-Tobler NE, Detmar M, Halin C. Coxsackie- and adenovirus receptor (CAR) is expressed in lymphatic vessels in human skin and affects lymphatic endothelial cell function in vitro. Experimental Cell Research. 315: 336-47. PMID 19007771 DOI: 10.1016/J.Yexcr.2008.10.020 |
0.492 |
|
| 2009 |
Kajiya K, Sawane M, Huggenberger R, Detmar M. Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis. The Journal of Investigative Dermatology. 129: 1292-8. PMID 19005491 DOI: 10.1038/Jid.2008.351 |
0.463 |
|
| 2009 |
Jurisic G, Detmar M. Lymphatic endothelium in health and disease. Cell and Tissue Research. 335: 97-108. PMID 18648856 DOI: 10.1007/S00441-008-0644-2 |
0.432 |
|
| 2009 |
Kajiya K, Kawai E, Kishimoto J, Detmar M. A novel mechanism of cutaneous photo-aging mediated by the impairment of lymphatic function and the protective role of a lymphatic-promoting compound International Journal of Cosmetic Science. 32: 316-316. DOI: 10.1111/J.1468-2494.2010.00579_4.X |
0.386 |
|
| 2008 |
Cueni LN, Detmar M. The lymphatic system in health and disease. Lymphatic Research and Biology. 6: 109-22. PMID 19093783 DOI: 10.1089/Lrb.2008.1008 |
0.399 |
|
| 2008 |
Halin C, Detmar M. Chapter 1. Inflammation, angiogenesis, and lymphangiogenesis. Methods in Enzymology. 445: 1-25. PMID 19022053 DOI: 10.1016/S0076-6879(08)03001-2 |
0.444 |
|
| 2008 |
Shin JW, Jurisic G, Detmar M. Lymphatic-specific expression of dipeptidyl peptidase IV and its dual role in lymphatic endothelial function. Experimental Cell Research. 314: 3048-56. PMID 18708048 DOI: 10.1016/J.Yexcr.2008.07.024 |
0.492 |
|
| 2008 |
Shin JW, Huggenberger R, Detmar M. Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis Blood. 112: 2318-2326. PMID 18614759 DOI: 10.1182/Blood-2008-05-156331 |
0.46 |
|
| 2008 |
Banziger-Tobler NE, Halin C, Kajiya K, Detmar M. Growth hormone promotes lymphangiogenesis. American Journal of Pathology. 173: 586-597. PMID 18583315 DOI: 10.2353/Ajpath.2008.080060 |
0.48 |
|
| 2008 |
Dadras SS, Skrzypek A, Nguyen L, Shin JW, Schulz MM, Arbiser J, Mihm MC, Detmar M. Prox-1 promotes invasion of kaposiform hemangioendotheliomas. The Journal of Investigative Dermatology. 128: 2798-806. PMID 18580962 DOI: 10.1038/Jid.2008.176 |
0.473 |
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| 2008 |
Halin C, Fahrngruber H, Meingassner JG, Bold G, Littlewood-Evans A, Stuetz A, Detmar M. Inhibition of Chronic and Acute Skin Inflammation by Treatment with a Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor American Journal of Pathology. 173: 265-277. PMID 18535184 DOI: 10.2353/Ajpath.2008.071074 |
0.474 |
|
| 2008 |
Rinderknecht M, Detmar M. Tumor lymphangiogenesis and melanoma metastasis Journal of Cellular Physiology. 216: 347-354. PMID 18481261 DOI: 10.1002/Jcp.21494 |
0.427 |
|
| 2008 |
Roesli C, Mumprecht V, Neri D, Detmar M. Identification of the surface-accessible, lineage-specific vascular proteome by two-dimensional peptide mapping The Faseb Journal. 22: 1933-1944. PMID 18180333 DOI: 10.1096/Fj.07-100529 |
0.361 |
|
| 2008 |
Kajiya K, Huggenberger R, Drinnenberg I, Ma B, Detmar M. Nitric oxide mediates lymphatic vessel activation via soluble guanylate cyclase α1β1-impact on inflammation The Faseb Journal. 22: 530-537. PMID 17855621 DOI: 10.1096/Fj.07-8873Com |
0.485 |
|
| 2008 |
Dadras SS, Lange-Asschenfeldt B, Muzikansky A, Mihm MC, Detmar M. Tumor Lymphangiogenesis Predicts Melanoma Metastasis to Sentinel Lymph Nodes Journal of Cutaneous Pathology. 32: 84-84. DOI: 10.1111/J.0303-6987.2005.320Bd.X |
0.356 |
|
| 2007 |
Liersch R, Detmar M. Lymphangiogenesis in development and disease. Thrombosis and Haemostasis. 98: 304-10. PMID 17721611 |
0.327 |
|
| 2007 |
Halin C, Tobler NE, Vigl B, Brown LF, Detmar M. VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes. Blood. 110: 3158-67. PMID 17625067 DOI: 10.1182/Blood-2007-01-066811 |
0.471 |
|
| 2007 |
Kajiya K, Kunstfeld R, Chung JH, Detmar M. Reduction of lymphatic vessels in photodamaged human skin. Journal of Dermatological Science. 47: 241-243. PMID 17572071 DOI: 10.1016/J.Jdermsci.2007.05.003 |
0.435 |
|
| 2007 |
Trachsel E, Kaspar M, Bootz F, Detmar M, Neri D. A human mAb specific to oncofetal fibronectin selectively targets chronic skin inflammation in vivo. Journal of Investigative Dermatology. 127: 881-886. PMID 17185984 DOI: 10.1038/Sj.Jid.5700653 |
0.359 |
|
| 2007 |
Hirakawa S, Brown LF, Kodama S, Paavonen K, Alitalo K, Detmar M. VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites. Blood. 109: 1010-7. PMID 17032920 DOI: 10.1182/Blood-2006-05-021758 |
0.409 |
|
| 2007 |
Liersch R, Detmar M. Lymphangiogenesis in development and disease Thrombosis and Haemostasis. 98: 304-310. DOI: 10.1160/Th07-04-0238 |
0.435 |
|
| 2007 |
Detmar M, Shin J. Angiogenesis and lymphangiogenesis in cutaneous cancer Experimental Dermatology. 16: 865-866. DOI: 10.1111/J.1600-0625.2007.00607_4.X |
0.327 |
|
| 2006 |
Wissmann C, Detmar M. Pathways Targeting Tumor Lymphangiogenesis Clinical Cancer Research. 12: 6865-6868. PMID 17145802 DOI: 10.1158/1078-0432.Ccr-06-1800 |
0.482 |
|
| 2006 |
Kajiya K, Hirakawa S, Detmar M. Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function. American Journal of Pathology. 169: 1496-1503. PMID 17003502 DOI: 10.2353/Ajpath.2006.060197 |
0.487 |
|
| 2006 |
Cueni LN, Detmar M. New insights into the molecular control of the lymphatic vascular system and its role in disease. Journal of Investigative Dermatology. 126: 2167-2177. PMID 16983326 DOI: 10.1038/Sj.Jid.5700464 |
0.452 |
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| 2006 |
Tobler NE, Detmar M. Tumor and lymph node lymphangiogenesis—impact on cancer metastasis Journal of Leukocyte Biology. 80: 691-696. PMID 16793912 DOI: 10.1189/Jlb.1105653 |
0.43 |
|
| 2006 |
Halin C, Detmar M. An unexpected connection: lymph node lymphangiogenesis and dendritic cell migration. Immunity. 24: 129-131. PMID 16473825 DOI: 10.1016/J.Immuni.2006.01.011 |
0.305 |
|
| 2006 |
Kajiya K, Detmar M. An important role of lymphatic vessels in the control of UVB-induced edema formation and inflammation. Journal of Investigative Dermatology. 126: 920-922. PMID 16470183 DOI: 10.1038/Sj.Jid.5700126 |
0.351 |
|
| 2006 |
Young HS, Summers AM, Read IR, Fairhurst DA, Plant DJ, Campalani E, Smith CH, Barker JN, Detmar MJ, Brenchley PE, Griffiths CE. Interaction between genetic control of vascular endothelial growth factor production and retinoid responsiveness in psoriasis. The Journal of Investigative Dermatology. 126: 453-9. PMID 16385345 DOI: 10.1038/sj.jid.5700096 |
0.314 |
|
| 2006 |
Shin JW, Min M, Larrieu-Lahargue F, Canron X, Kunstfeld R, Nguyen L, Henderson JE, Bikfalvi A, Detmar M, Hong YK. Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis. Molecular Biology of the Cell. 17: 576-84. PMID 16291864 DOI: 10.1091/Mbc.E05-04-0368 |
0.436 |
|
| 2006 |
Liersch R, Nay F, Lu L, Detmar M. Induction of lymphatic endothelial cell differentiation in embryoid bodies Blood. 107: 1214-1216. PMID 16195336 DOI: 10.1182/Blood-2005-08-3400 |
0.474 |
|
| 2006 |
Liersch R, Forkert R, Kajiya K, Nagy JA, Scadden D, Detmar M. Vascular endothelial growth factor (VEGF)-A induces recruitment of bone-marrow derived lymphatic endothelial progenitor cells Vascular Pharmacology. 45. DOI: 10.1016/J.Vph.2006.08.340 |
0.426 |
|
| 2005 |
Mamluk R, Klagsbrun M, Detmar M, Bielenberg DR. Soluble neuropilin targeted to the skin inhibits vascular permeability. Angiogenesis. 8: 217-27. PMID 16328161 DOI: 10.1007/S10456-005-9009-6 |
0.501 |
|
| 2005 |
Kajiya K, Hirakawa S, Ma B, Drinnenberg I, Detmar M. Hepatocyte growth factor promotes lymphatic vessel formation and function The Embo Journal. 24: 2885-2895. PMID 16052207 DOI: 10.1038/Sj.Emboj.7600763 |
0.483 |
|
| 2005 |
Hirakawa S, Kodama S, Kunstfeld R, Kajiya K, Brown LF, Detmar M. VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. The Journal of Experimental Medicine. 201: 1089-99. PMID 15809353 DOI: 10.1084/Jem.20041896 |
0.447 |
|
| 2005 |
Dadras SS, Lange-Asschenfeldt B, Velasco P, Nguyen L, Vora A, Muzikansky A, Jahnke K, Hauschild A, Hirakawa S, Mihm MC, Detmar M. Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 18: 1232-42. PMID 15803182 DOI: 10.1038/Modpathol.3800410 |
0.346 |
|
| 2005 |
Schacht V, Dadras SS, Johnson LA, Jackson DG, Hong YK, Detmar M. Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. The American Journal of Pathology. 166: 913-21. PMID 15743802 DOI: 10.1016/S0002-9440(10)62311-5 |
0.428 |
|
| 2005 |
Yano K, Kadoya K, Kajiya K, Hong YK, Detmar M. Ultraviolet B irradiation of human skin induces an angiogenic switch that is mediated by upregulation of vascular endothelial growth factor and by downregulation of thrombospondin-1. The British Journal of Dermatology. 152: 115-21. PMID 15656811 DOI: 10.1111/j.1365-2133.2005.06368.x |
0.347 |
|
| 2005 |
Hirakawa S, Fujii S, Kajiya K, Yano K, Detmar M. Vascular endothelial growth factor promotes sensitivity to ultraviolet B-induced cutaneous photodamage. Blood. 105: 2392-2399. PMID 15550485 DOI: 10.1182/Blood-2004-06-2435 |
0.449 |
|
| 2004 |
Park YW, Kang YM, Butterfield J, Detmar M, Goronzy JJ, Weyand CM. Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis. The American Journal of Pathology. 165: 2087-98. PMID 15579451 DOI: 10.1016/S0002-9440(10)63259-2 |
0.412 |
|
| 2004 |
Shin M, Matsuda K, Ishii O, Terai H, Kaazempur-Mofrad M, Borenstein J, Detmar M, Vacanti JP. Endothelialized networks with a vascular geometry in microfabricated poly(dimethyl siloxane). Biomedical Microdevices. 6: 269-78. PMID 15548874 DOI: 10.1023/B:Bmmd.0000048559.29932.27 |
0.373 |
|
| 2004 |
Dadras SS, Detmar M. Angiogenesis and lymphangiogenesis of skin cancers. Hematology/Oncology Clinics of North America. 18: 1059-70, viii. PMID 15474335 DOI: 10.1016/J.Hoc.2004.06.009 |
0.399 |
|
| 2004 |
Hong YK, Shin JW, Detmar M. Development of the lymphatic vascular system: a mystery unravels. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 462-73. PMID 15376314 DOI: 10.1002/Dvdy.20179 |
0.458 |
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| 2004 |
Yee KO, Streit M, Hawighorst T, Detmar M, Lawler J. Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-beta. The American Journal of Pathology. 165: 541-52. PMID 15277228 DOI: 10.1016/S0002-9440(10)63319-6 |
0.332 |
|
| 2004 |
Hong YK, Foreman K, Shin JW, Hirakawa S, Curry CL, Sage DR, Libermann T, Dezube BJ, Fingeroth JD, Detmar M. Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus. Nature Genetics. 36: 683-5. PMID 15220917 DOI: 10.1038/Ng1383 |
0.428 |
|
| 2004 |
Hirakawa S, Detmar M. New insights into the biology and pathology of the cutaneous lymphatic system. Journal of Dermatological Science. 35: 1-8. PMID 15194141 DOI: 10.1016/J.Jdermsci.2003.10.006 |
0.39 |
|
| 2004 |
North PE, Kahn T, Cordisco MR, Dadras SS, Detmar M, Frieden IJ. Multifocal lymphangioendotheliomatosis with thrombocytopenia: a newly recognized clinicopathological entity. Archives of Dermatology. 140: 599-606. PMID 15148106 DOI: 10.1001/Archderm.140.5.599 |
0.371 |
|
| 2004 |
Dadras SS, North PE, Bertoncini J, Mihm MC, Detmar M. Infantile hemangiomas are arrested in an early developmental vascular differentiation state. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 17: 1068-79. PMID 15143338 DOI: 10.1038/Modpathol.3800153 |
0.447 |
|
| 2004 |
Hong YK, Lange-Asschenfeldt B, Velasco P, Hirakawa S, Kunstfeld R, Brown LF, Bohlen P, Senger DR, Detmar M. VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1111-3. PMID 15132990 DOI: 10.1096/Fj.03-1179Fje |
0.457 |
|
| 2004 |
Kunstfeld R, Hirakawa S, Hong YK, Schacht V, Lange-Asschenfeldt B, Velasco P, Lin C, Fiebiger E, Wei X, Wu Y, Hicklin D, Bohlen P, Detmar M. Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. Blood. 104: 1048-57. PMID 15100155 DOI: 10.1182/Blood-2003-08-2964 |
0.47 |
|
| 2004 |
Lawler J, Detmar M. Tumor progression: the effects of thrombospondin-1 and -2. The International Journal of Biochemistry & Cell Biology. 36: 1038-45. PMID 15094119 DOI: 10.1016/J.Biocel.2004.01.008 |
0.455 |
|
| 2004 |
Detmar M. Evidence for Vascular Endothelial Growth Factor (VEGF) as a Modifier Gene in Psoriasis Journal of Investigative Dermatology. 122. PMID 14962120 DOI: 10.1046/J.0022-202X.2003.22140.X |
0.424 |
|
| 2004 |
Yano K, Kajiya K, Ishiwata M, Hong YK, Miyakawa T, Detmar M. Ultraviolet B-induced skin angiogenesis is associated with a switch in the balance of vascular endothelial growth factor and thrombospondin-1 expression. The Journal of Investigative Dermatology. 122: 201-8. PMID 14962109 DOI: 10.1046/J.0022-202X.2003.22101.X |
0.469 |
|
| 2004 |
Detmar M. VEGF up-regulates DSCR1: more surprises Blood. 104: 6-7. DOI: 10.1182/Blood-2004-04-1495 |
0.455 |
|
| 2003 |
Noh YH, Matsuda K, Hong YK, Kunstfeld R, Riccardi L, Koch M, Oura H, Dadras SS, Streit M, Detmar M. An N-terminal 80 kDa recombinant fragment of human thrombospondin-2 inhibits vascular endothelial growth factor induced endothelial cell migration in vitro and tumor growth and angiogenesis in vivo. The Journal of Investigative Dermatology. 121: 1536-43. PMID 14675207 DOI: 10.1046/J.1523-1747.2003.12643.X |
0.488 |
|
| 2003 |
Hong YK, Detmar M. Prox1, master regulator of the lymphatic vasculature phenotype. Cell and Tissue Research. 314: 85-92. PMID 12883994 DOI: 10.1007/S00441-003-0747-8 |
0.474 |
|
| 2003 |
Yahata Y, Shirakata Y, Tokumaru S, Yamasaki K, Sayama K, Hanakawa Y, Detmar M, Hashimoto K. Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation Journal of Biological Chemistry. 278: 40026-40031. PMID 12874294 DOI: 10.1074/Jbc.M301866200 |
0.45 |
|
| 2003 |
Schacht V, Ramirez MI, Hong YK, Hirakawa S, Feng D, Harvey N, Williams M, Dvorak AM, Dvorak HF, Oliver G, Detmar M. T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. The Embo Journal. 22: 3546-56. PMID 12853470 DOI: 10.1093/Emboj/Cdg342 |
0.464 |
|
| 2003 |
Streit M, Detmar M. Angiogenesis, lymphangiogenesis, and melanoma metastasis Oncogene. 22: 3172-3179. PMID 12789293 DOI: 10.1038/Sj.Onc.1206457 |
0.476 |
|
| 2003 |
Dadras SS, Paul T, Bertoncini J, Brown LF, Muzikansky A, Jackson DG, Ellwanger U, Garbe C, Mihm MC, Detmar M. Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival. The American Journal of Pathology. 162: 1951-60. PMID 12759251 DOI: 10.1016/S0002-9440(10)64328-3 |
0.432 |
|
| 2003 |
Xia YP, Li B, Hylton D, Detmar M, Yancopoulos GD, Rudge JS. Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. Blood. 102: 161-8. PMID 12649136 DOI: 10.1182/Blood-2002-12-3793 |
0.465 |
|
| 2003 |
Gruss CJ, Satyamoorthy K, Berking C, Lininger J, Nesbit M, Schaider H, Liu ZJ, Oka M, Hsu MY, Shirakawa T, Li G, Bogenrieder T, Carmeliet P, El-Deiry WS, Eck SL, ... ... Detmar M, et al. Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice. The Journal of Investigative Dermatology. 120: 683-92. PMID 12648235 DOI: 10.1046/J.1523-1747.2003.12112.X |
0.447 |
|
| 2003 |
Hirakawa S, Hong YK, Harvey N, Schacht V, Matsuda K, Libermann T, Detmar M. Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells. The American Journal of Pathology. 162: 575-86. PMID 12547715 DOI: 10.1016/S0002-9440(10)63851-5 |
0.496 |
|
| 2003 |
Yano K, Brown LF, Lawler J, Miyakawa T, Detmar M. Thrombospondin-1 plays a critical role in the induction of hair follicle involution and vascular regression during the catagen phase. The Journal of Investigative Dermatology. 120: 14-9. PMID 12535193 DOI: 10.1046/J.1523-1747.2003.12045.X |
0.452 |
|
| 2003 |
Oura H, Bertoncini J, Velasco P, Brown LF, Carmeliet P, Detmar M. A critical role of placental growth factor in the induction of inflammation and edema formation. Blood. 101: 560-7. PMID 12393422 DOI: 10.1182/Blood-2002-05-1516 |
0.455 |
|
| 2002 |
Nagy JA, Vasile E, Feng D, Sundberg C, Brown LF, Detmar MJ, Lawitts JA, Benjamin L, Tan X, Manseau EJ, Dvorak AM, Dvorak HF. Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis. The Journal of Experimental Medicine. 196: 1497-506. PMID 12461084 DOI: 10.1084/jem.20021244 |
0.379 |
|
| 2002 |
Hawighorst T, Oura H, Streit M, Janes L, Nguyen L, Brown LF, Oliver G, Jackson DG, Detmar M. Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice. Oncogene. 21: 7945-56. PMID 12439745 DOI: 10.1038/Sj.Onc.1205956 |
0.446 |
|
| 2002 |
Chung JH, Yano K, Lee MK, Youn CS, Seo JY, Kim KH, Cho KH, Eun HC, Detmar M. Differential effects of photoaging vs intrinsic aging on the vascularization of human skin. Archives of Dermatology. 138: 1437-42. PMID 12437449 DOI: 10.1001/Archderm.138.11.1437 |
0.353 |
|
| 2002 |
Hong YK, Harvey N, Noh YH, Schacht V, Hirakawa S, Detmar M, Oliver G. Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 225: 351-7. PMID 12412020 DOI: 10.1002/Dvdy.10163 |
0.48 |
|
| 2002 |
Detmar M, Hirakawa S. The Formation of Lymphatic Vessels and Its Importance in the Setting of Malignancy Journal of Experimental Medicine. 196: 713-718. PMID 12235205 DOI: 10.1084/Jem.20021346 |
0.427 |
|
| 2002 |
Yano K, Oura H, Detmar M. Targeted overexpression of the angiogenesis inhibitor thrombospondin-1 in the epidermis of transgenic mice prevents ultraviolet-B-induced angiogenesis and cutaneous photo-damage. The Journal of Investigative Dermatology. 118: 800-5. PMID 11982756 DOI: 10.1046/J.1523-1747.2002.01752.X |
0.424 |
|
| 2002 |
Sundberg C, Kowanetz M, Brown LF, Detmar M, Dvorak HF. Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo. Laboratory Investigation; a Journal of Technical Methods and Pathology. 82: 387-401. PMID 11950897 DOI: 10.1038/Labinvest.3780433 |
0.371 |
|
| 2002 |
Hawighorst T, Skobe M, Streit M, Hong YK, Velasco P, Brown LF, Riccardi L, Lange-Asschenfeldt B, Detmar M. Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth. The American Journal of Pathology. 160: 1381-92. PMID 11943723 DOI: 10.1016/S0002-9440(10)62565-5 |
0.477 |
|
| 2002 |
Oliver G, Detmar M. The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature. Genes & Development. 16: 773-83. PMID 11937485 DOI: 10.1101/Gad.975002 |
0.369 |
|
| 2002 |
Wigle JT, Harvey N, Detmar M, Lagutina I, Grosveld G, Gunn MD, Jackson DG, Oliver G. An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype. The Embo Journal. 21: 1505-13. PMID 11927535 DOI: 10.1093/Emboj/21.7.1505 |
0.455 |
|
| 2002 |
Senger DR, Perruzzi CA, Streit M, Koteliansky VE, de Fougerolles AR, Detmar M. The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. The American Journal of Pathology. 160: 195-204. PMID 11786413 DOI: 10.1016/S0002-9440(10)64363-5 |
0.329 |
|
| 2002 |
Lange-Asschenfeldt B, Weninger W, Velasco P, Kyriakides TR, von Andrian UH, Bornstein P, Detmar M. Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice. Blood. 99: 538-45. PMID 11781236 DOI: 10.1182/Blood.V99.2.538 |
0.413 |
|
| 2001 |
Lange-Asschenfeldt B, Velasco P, Streit M, Hawighorst T, Pike SE, Tosato G, Detmar M. The angiogenesis inhibitor vasostatin does not impair wound healing at tumor-inhibiting doses Journal of Investigative Dermatology. 117: 1036-1041. PMID 11710910 DOI: 10.1046/J.0022-202X.2001.01519.X |
0.416 |
|
| 2001 |
Skobe M, Hamberg LM, Hawighorst T, Schirner M, Wolf GL, Alitalo K, Detmar M. Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma. The American Journal of Pathology. 159: 893-903. PMID 11549582 DOI: 10.1016/S0002-9440(10)61765-8 |
0.482 |
|
| 2001 |
Hawighorst T, Velasco P, Streit M, Hong YK, Kyriakides TR, Brown LF, Bornstein P, Detmar M. Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism. The Embo Journal. 20: 2631-40. PMID 11387198 DOI: 10.1093/Emboj/20.11.2631 |
0.44 |
|
| 2001 |
Yano K, Brown LF, Detmar M. Control of hair growth and follicle size by VEGF-mediated angiogenesis. The Journal of Clinical Investigation. 107: 409-17. PMID 11181640 DOI: 10.1172/Jci11317 |
0.442 |
|
| 2001 |
Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, Riccardi L, Alitalo K, Claffey K, Detmar M. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nature Medicine. 7: 192-8. PMID 11175850 DOI: 10.1038/84643 |
0.435 |
|
| 2001 |
Echtermeyer F, Streit M, Wilcox-Adelman S, Saoncella S, Denhez F, Detmar M, Goetinck PF. Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4 Journal of Clinical Investigation. 107. PMID 11160142 DOI: 10.1172/Jci10559 |
0.36 |
|
| 2000 |
Skobe M, Detmar M. Structure, Function, and Molecular Control of the Skin Lymphatic System Journal of Investigative Dermatology Symposium Proceedings. 5: 14-19. PMID 11147669 DOI: 10.1046/J.1087-0024.2000.00001.X |
0.469 |
|
| 2000 |
Detmar M. The role of VEGF and thrombospondins in skin angiogenesis. Journal of Dermatological Science. 24. PMID 11137400 DOI: 10.1016/S0923-1811(00)00145-6 |
0.468 |
|
| 2000 |
Streit M, Velasco P, Riccardi L, Spencer L, Brown LF, Janes L, Lange-Asschenfeldt B, Yano K, Hawighorst T, Iruela-Arispe L, Detmar M. Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice. The Embo Journal. 19: 3272-82. PMID 10880440 DOI: 10.1093/Emboj/19.13.3272 |
0.398 |
|
| 2000 |
Kishimoto J, Ehama R, Ge Y, Kobayashi T, Nishiyama T, Detmar M, Burgeson RE. In vivo detection of human vascular endothelial growth factor promoter activity in transgenic mouse skin. American Journal of Pathology. 157: 103-110. PMID 10880381 DOI: 10.1016/S0002-9440(10)64522-1 |
0.412 |
|
| 2000 |
Detmar M, Velasco P, Richard L, Claffey KP, Streit M, Riccardi L, Skobe M, Brown LF. Expression of vascular endothelial growth factor induces an invasive phenotype in human squamous cell carcinomas. The American Journal of Pathology. 156: 159-67. PMID 10623663 DOI: 10.1016/S0002-9440(10)64715-3 |
0.478 |
|
| 1999 |
Richard L, Velasco P, Detmar M. Isolation and culture of microvascular endothelial cells. Methods in Molecular Medicine. 18: 261-269. PMID 21370183 DOI: 10.1385/0-89603-516-6:261 |
0.475 |
|
| 1999 |
Streit M, Riccardi L, Velasco P, Brown LF, Hawighorst T, Bornstein P, Detmar M. Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 96: 14888-93. PMID 10611308 DOI: 10.1073/Pnas.96.26.14888 |
0.428 |
|
| 1999 |
Skobe M, Brown LF, Tognazzi K, Ganju RK, Dezube BJ, Alitalo K, Detmar M. Vascular endothelial growth factor-C (VEGF-C) and its receptors KDR and flt-4 are expressed in AIDS-associated Kaposi's sarcoma. The Journal of Investigative Dermatology. 113: 1047-53. PMID 10594750 DOI: 10.1046/J.1523-1747.1999.00798.X |
0.481 |
|
| 1999 |
Streit M, Velasco P, Brown LF, Skobe M, Richard L, Riccardi L, Lawler J, Detmar M. Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas. The American Journal of Pathology. 155: 441-52. PMID 10433937 DOI: 10.1016/S0002-9440(10)65140-1 |
0.398 |
|
| 1999 |
Penc SF, Pomahac B, Eriksson E, Detmar M, Gallo RL. Dermatan sulfate activates nuclear factor-kappab and induces endothelial and circulating intercellular adhesion molecule-1. The Journal of Clinical Investigation. 103: 1329-35. PMID 10225976 DOI: 10.1172/Jci4742 |
0.378 |
|
| 1998 |
Detmar M, Brown LF, Schön MP, Elicker BM, Velasco P, Richard L, Fukumura D, Monsky W, Claffey KP, Jain RK. Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. The Journal of Investigative Dermatology. 111: 1-6. PMID 9665379 DOI: 10.1046/J.1523-1747.1998.00262.X |
0.5 |
|
| 1998 |
Richard L, Velasco P, Detmar M. A Simple Immunomagnetic Protocol for the Selective Isolation and Long-Term Culture of Human Dermal Microvascular Endothelial Cells Experimental Cell Research. 240: 1-6. PMID 9570915 DOI: 10.1006/Excr.1998.3936 |
0.464 |
|
| 1998 |
Claffey KP, Shih SC, Mullen A, Dziennis S, Cusick JL, Abrams KR, Lee SW, Detmar M. Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability Molecular Biology of the Cell. 9: 469-481. PMID 9450968 DOI: 10.1091/Mbc.9.2.469 |
0.398 |
|
| 1998 |
Detmar M, Velasco P, Richard L, Claffey K, Brown L. A novel function of vascular endothelial growth factor in tumor progression: Induction of a more malignant tumor phenotype with enhanced infiltration of squamous cell carcinomas Journal of Dermatological Science. 16: S33. DOI: 10.1016/S0923-1811(98)83192-7 |
0.444 |
|
| 1997 |
Senger DR, Claffey KP, Benes JE, Perruzzi CA, Sergiou AP, Detmar M. Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins. Proceedings of the National Academy of Sciences of the United States of America. 94: 13612-7. PMID 9391074 DOI: 10.1073/Pnas.94.25.13612 |
0.431 |
|
| 1997 |
Watanabe Y, Lee SW, Detmar M, Ajioka I, Dvorak HF. Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells. Oncogene. 14: 2025-32. PMID 9160882 DOI: 10.1038/Sj.Onc.1201033 |
0.478 |
|
| 1997 |
Smyth AP, Rook SL, Detmar M, Robinson GS. Antisense oligonucleotides inhibit vascular endothelial growth factor/vascular permeability factor expression in normal human epidermal keratinocytes Journal of Investigative Dermatology. 108: 523-526. PMID 9077485 DOI: 10.1111/1523-1747.Ep12289740 |
0.441 |
|
| 1997 |
Detmar M, Brown LF, Berse B, Jackman RW, Elicker BM, Dvorak HF, Claffey KP. Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin. The Journal of Investigative Dermatology. 108: 263-8. PMID 9036922 DOI: 10.1111/1523-1747.Ep12286453 |
0.497 |
|
| 1997 |
Brown LF, Detmar M, Claffey K, Nagy JA, Feng D, Dvorak AM, Dvorak HF. Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine. Exs. 79: 233-69. PMID 9002222 DOI: 10.1007/978-3-0348-9006-9_10 |
0.379 |
|
| 1996 |
Detmar M. Molecular regulation of angiogenesis in the skin. Journal of Investigative Dermatology. 106: 207-208. PMID 8601716 DOI: 10.1111/1523-1747.Ep12340457 |
0.342 |
|
| 1996 |
Treudler R, Zouboulis CC, Büttner P, Detmar M, Orfanos CE. Enhanced Interaction of Patients' Lymphocytes With Human Dermal Microvascular Endothelial Cell Cultures in Active Adamantiades-Behçet Disease Archives of Dermatology. 132: 1323-1329. DOI: 10.1001/Archderm.1996.03890350065011 |
0.34 |
|
| 1995 |
Brown LF, Harrist TJ, Yeo KT, Stahle-Backdahl M, Jackman RW, Berse B, Tognazzi K, Dvorak HF, Detmar M. Increased expression of vascular permeability factor (vascular endothelial growth factor) in bullous pemphigoid, dermatitis herpetiformis, and erythema multiforme Journal of Investigative Dermatology. 104: 744-749. PMID 7738351 DOI: 10.1111/1523-1747.Ep12606974 |
0.483 |
|
| 1995 |
Detmar M, Yeo K, Nagy JA, Water Lvd, Brown LF, Berse B, Elicker BM, Ledbetter S, Dvorak HF. Keratinocyte-Derived Vascular Permeability Factor (Vascular Endothelial Growth Factor) Is a Potent Mitogen for Dermal Microvascular Endothelial Cells Journal of Investigative Dermatology. 105: 44-50. PMID 7615975 DOI: 10.1111/1523-1747.Ep12312542 |
0.469 |
|
| 1995 |
Dvorak HF, Detmar M, Claffey KP, Nagy JA, van de Water L, Senger DR. Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation. International Archives of Allergy and Immunology. 107: 233-5. PMID 7542074 DOI: 10.1159/000236988 |
0.484 |
|
| 1994 |
Detmar M, Geilen CC, Wieder T, Orfanos CE, Reutter W. Phospholipid analogue hexadecylphosphocholine inhibits proliferation and phosphatidylcholine biosynthesis of human epidermal keratinocytes in vitro. The Journal of Investigative Dermatology. 102: 490-4. PMID 8151126 DOI: 10.1111/1523-1747.Ep12373109 |
0.335 |
|
| 1994 |
Detmar M, Brown LF, Claffey KP, Yeo KT, Kocher O, Jackman RW, Berse B, Dvorak HF. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis Journal of Experimental Medicine. 180: 1141-1146. PMID 8064230 DOI: 10.1084/Jem.180.3.1141 |
0.474 |
|
| 1994 |
Blume U, Schön MP, Zouboulis CC, Detmar M, Orfanos CE. Vellus hair follicle-derived keratinocyte culture: a new experimental model in human hair research. Skin Pharmacology and Physiology. 7: 27-32. PMID 8003319 DOI: 10.1159/000211270 |
0.301 |
|
| 1994 |
Detmar M, Brown LF, Claffey KP, Yeo K, Dvorak HF. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis Journal of Investigative Dermatology. 103: 397. DOI: 10.5555/Uri:Pii:0022202X94921830 |
0.425 |
|
| 1993 |
Hettmannsperger U, Tenorio S, Orfanos CE, Detmar M. Corticosteroids induce proliferation but do not influence TNF- or IL-1β-induced ICAM-1 expression of human dermal microvascular endothelial cells in vitro Archives of Dermatological Research. 285: 347-351. PMID 8105755 DOI: 10.1007/Bf00371835 |
0.358 |
|
| 1993 |
Treudler R, Zouboulis C, Büttner P, Detmar M, Orfanos C. P 130 Alterations of lymphocyte subsets in patients with Adamantiades-Behçet's disease and enhanced lymphocyte interaction with human dermal microvascular endothelial cells in vitro Revue De MéDecine Interne. 14: 118. DOI: 10.1016/S0248-8663(05)82432-4 |
0.365 |
|
| 1993 |
Detmar M, Schaart F, Blume U, Orfanos CE. Culture of hair matrix and follicular keratinocytes Journal of Investigative Dermatology. 101. DOI: 10.1016/0022-202X(93)90513-H |
0.31 |
|
| 1992 |
Asada M, Schaart F, Detmar M, Mischke D, Almeida HLd, Gollnick H, Orfanos CE. Growth characteristics and differentiation of basal cell carcinoma in vitro--immunohistochemical, gel electrophoretic, and ultrastructural analysis. Journal of Investigative Dermatology. 99: 474-481. PMID 1383350 DOI: 10.1111/1523-1747.Ep12616161 |
0.323 |
|
| 1992 |
Detmar M, Tenorio S, Hettmannsperger U, Ruszczak Z, Orfanos CE. Cytokine regulation of proliferation and ICAM-1 expression of human dermal microvascular endothelial cells in vitro. Journal of Investigative Dermatology. 98: 147-153. PMID 1346267 DOI: 10.1111/1523-1747.Ep12555746 |
0.312 |
|
| 1991 |
Imcke E, Ruszczak Z, Silva AM, Detmar M, Orfanos CE. Cultivation of human dermal microvascular endothelial cells in vitro: Immunocytochemical and ultrastructural characterization and effect of treatment with three synthetic retinoids Archives of Dermatological Research. 283: 149-157. PMID 1831018 DOI: 10.1007/Bf00372054 |
0.448 |
|
| 1991 |
Detmar M, Hettmannsperger U, Owsianowski M, Tenorio S, Golinick H, Orfanos CE. 6 Cytokine stimulated human dermal microvascular endothelial cells (HDMEC) are a major source for interleukin 6 Journal of Investigative Dermatology. 96: 999. DOI: 10.5555/Uri:Pii:0022202X91912027 |
0.386 |
|
| 1990 |
Detmar M, Imcke E, Ruszczak Z, Orfanos CE. Effect of Recombinant Tumor Necrosis Factor-Alpha on Cultured Microvascular Endothelial Cells Derived From Human Dermis Journal of Investigative Dermatology. 95. PMID 1979587 DOI: 10.1111/1523-1747.Ep12875807 |
0.425 |
|
| 1990 |
Ruszczak Z, Detmar M, Imcke E, Orfanos CE. Effects of rIFN alpha, beta, and gamma on the morphology, proliferation, and cell surface antigen expression of human dermal microvascular endothelial cells in vitro. Journal of Investigative Dermatology. 95: 693-699. PMID 1979080 DOI: 10.1111/1523-1747.Ep12514496 |
0.341 |
|
| 1989 |
Stadler R, Detmar M, Stephanek K, Bangemann C, Orfanos CE. A rapid fluorometric assay for the determination of keratinocyte proliferation in vitro. Journal of Investigative Dermatology. 93: 532-534. PMID 2476513 DOI: 10.1111/1523-1747.Ep12284080 |
0.311 |
|
| 1989 |
Xia L, Zouboulis C, Detmar M, Mayer-da-Silva A, Stadler R, Orfanos CE. Isolation of human sebaceous glands and cultivation of sebaceous gland-derived cells as an in vitro model. Journal of Investigative Dermatology. 93: 315-321. DOI: 10.1016/0022-202X(89)90050-X |
0.327 |
|
| 1987 |
Imcke E, Mayer-da-Silva A, Detmar M, Tiel H, Stadler R, Orfanos CE. Growth of human hair follicle keratinocytes in vitro. Ultrastructural features of a new model. Journal of the American Academy of Dermatology. 17: 779-786. PMID 2445799 DOI: 10.1016/S0190-9622(87)70263-1 |
0.323 |
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