Luigi Bubacco - Publications

University of Padua (Italy) 

101 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Filippini A, Mutti V, Faustini G, Longhena F, Ramazzina I, Rizzi F, Kaganovich A, Roosen DA, Landeck N, Duffy M, Tessari I, Bono F, Fiorentini C, Greggio E, Bubacco L, et al. Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes. Glia. PMID 33045109 DOI: 10.1002/glia.23920  0.52
2020 Sulzer D, Antonini A, Leta V, Nordvig A, Smeyne RJ, Goldman JE, Al-Dalahmah O, Zecca L, Sette A, Bubacco L, Meucci O, Moro E, Harms AS, Xu Y, Fahn S, et al. COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside. Npj Parkinson's Disease. 6: 18. PMID 32885037 DOI: 10.1038/S41531-020-00123-0  0.316
2020 Moretti P, Mariani P, Ortore MG, Plotegher N, Bubacco L, Beltramini M, Spinozzi F. Comprehensive Structural and Thermodynamic Analysis of Pre-Fibrillar WT α-Synuclein and its G51D, E46K and A53T Mutants by a Combination of Small-Angle X-Ray Scattering and Variational Bayesian Weighting. Journal of Chemical Information and Modeling. PMID 32866007 DOI: 10.1021/Acs.Jcim.0C00807  0.346
2020 Munari F, Barracchia CG, Parolini F, Tira R, Bubacco L, Assfalg M, D'Onofrio M. Semisynthetic Modification of Tau Protein with Di-Ubiquitin Chains for Aggregation Studies. International Journal of Molecular Sciences. 21. PMID 32575755 DOI: 10.3390/Ijms21124400  0.356
2020 Barracchia CG, Tira R, Parolini F, Munari F, Bubacco L, Spyroulias GA, D'Onofrio M, Assfalg M. Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau. Molecules (Basel, Switzerland). 25. PMID 32545360 DOI: 10.3390/Molecules25112716  0.303
2020 Antonini A, Bravi D, Sandre M, Bubacco L. Immunization therapies for Parkinson's disease: state of the art and considerations for future clinical trials. Expert Opinion On Investigational Drugs. PMID 32419521 DOI: 10.1080/13543784.2020.1771693  0.343
2020 Bellucci A, Bubacco L, Longhena F, Parrella E, Faustini G, Porrini V, Bono F, Missale C, Pizzi M. Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson's Disease. Frontiers in Aging Neuroscience. 12: 68. PMID 32265684 DOI: 10.3389/Fnagi.2020.00068  0.39
2020 Munari F, Barracchia CG, Franchin C, Parolini F, Capaldi S, Romeo A, Bubacco L, Assfalg M, Arrigoni G, D'Onofrio M. Semisynthetic and enzyme-mediated conjugate preparations illuminate the ubiquitination-dependent aggregation of protein tau. Angewandte Chemie (International Ed. in English). PMID 32022419 DOI: 10.1002/Anie.201916756  0.356
2019 Masato A, Plotegher N, Boassa D, Bubacco L. Impaired dopamine metabolism in Parkinson's disease pathogenesis. Molecular Neurodegeneration. 14: 35. PMID 31488222 DOI: 10.1186/S13024-019-0332-6  0.392
2019 Capucciati A, Galliano M, Bubacco L, Zecca L, Casella L, Monzani E, Nicolis S. Neuronal proteins as targets of 3-hydroxykynurenine: Implications in neurodegenerative diseases. Acs Chemical Neuroscience. PMID 31298828 DOI: 10.1021/Acschemneuro.9B00265  0.381
2019 Biosa A, De Lazzari F, Masato A, Filograna R, Plotegher N, Beltramini M, Bubacco L, Bisaglia M. Superoxide Dismutases SOD1 and SOD2 Rescue the Toxic Effect of Dopamine-Derived Products in Human SH-SY5Y Neuroblastoma Cells. Neurotoxicity Research. PMID 31228093 DOI: 10.1007/S12640-019-00078-Y  0.364
2019 Russo I, Kaganovich A, Ding J, Landeck N, Mamais A, Varanita T, Biosa A, Tessari I, Bubacco L, Greggio E, Cookson MR. Transcriptase analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils. Neurobiology of Disease. PMID 31102768 DOI: 10.1016/J.Nbd.2019.05.012  0.555
2019 Plotegher N, Bubacco L, Greggio E, Civiero L. Ceramides in Parkinson's Disease: From Recent Evidence to New Hypotheses. Frontiers in Neuroscience. 13: 330. PMID 31001082 DOI: 10.3389/Fnins.2019.00330  0.34
2018 Russo I, Di Benedetto G, Kaganovich A, Ding J, Mercatelli D, Morari M, Cookson MR, Bubacco L, Greggio E. Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4. Journal of Neuroinflammation. 15: 297. PMID 30368241 DOI: 10.1186/S12974-018-1337-8  0.623
2018 De Lazzari F, Bubacco L, Whitworth AJ, Bisaglia M. Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson's Disease. Aging and Disease. 9: 716-728. PMID 30090659 DOI: 10.14336/Ad.2017.1018  0.369
2018 Faustini G, Longhena F, Varanita T, Bubacco L, Pizzi M, Missale C, Benfenati F, Björklund A, Spano P, Bellucci A. Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson's disease. Acta Neuropathologica. PMID 30046897 DOI: 10.1007/S00401-018-1892-1  0.401
2018 Biosa A, Arduini I, Soriano ME, Giorgio V, Bernardi P, Bisaglia M, Bubacco L. Dopamine oxidation products as mitochondrial endotoxins, a potential molecular mechanism for preferential neurodegeneration in Parkinson Disease. Acs Chemical Neuroscience. PMID 29906101 DOI: 10.1021/Acschemneuro.8B00276  0.344
2018 Medeiros AT, Bubacco L, Morgan JR. Impacts of increased α-synuclein on clathrin-mediated endocytosis at synapses: implications for neurodegenerative diseases. Neural Regeneration Research. 13: 647-648. PMID 29722314 DOI: 10.4103/1673-5374.230289  0.605
2018 Biosa A, Outeiro TF, Bubacco L, Bisaglia M. Diabetes Mellitus as a Risk Factor for Parkinson's Disease: a Molecular Point of View. Molecular Neurobiology. PMID 29594935 DOI: 10.1007/S12035-018-1025-9  0.36
2018 Biosa A, Sanchez-Martinez A, Filograna R, Terriente-Felix A, Alam SM, Beltramini M, Bubacco L, Bisaglia M, Whitworth AJ. Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss. Human Molecular Genetics. PMID 29529199 DOI: 10.1093/Hmg/Ddy069  0.361
2018 Longhena F, Faustini G, Varanita T, Zaltieri M, Porrini V, Tessari I, Poliani PL, Missale C, Borroni B, Padovani A, Bubacco L, Pizzi M, Spano P, Bellucci A. Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains. Brain Pathology (Zurich, Switzerland). PMID 29330884 DOI: 10.1111/Bpa.12587  0.373
2018 De Lazzari F, Frighetto G, Stramazzo M, Bubacco L, Whitworth A, Malacrida S, Zordan MA, Megighian A, Sandrelli F, Bisaglia M. The involvement of the anti-oxidant protein DJ-1 in SOD1 maturation pathway: implications for neurobehavioral deficits in Drosophila Melanogaster Free Radical Biology and Medicine. 120: S75. DOI: 10.1016/J.Freeradbiomed.2018.04.249  0.332
2017 Medeiros AT, Soll LG, Tessari I, Bubacco L, Morgan JR. α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling. Frontiers in Cellular Neuroscience. 11: 388. PMID 29321725 DOI: 10.3389/Fncel.2017.00388  0.628
2017 Civiero L, Cogo S, Kiekens A, Morganti C, Tessari I, Lobbestael E, Baekelandt V, Taymans JM, Chartier-Harlin MC, Franchin C, Arrigoni G, Lewis PA, Piccoli G, Bubacco L, Cookson MR, et al. PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2. Frontiers in Molecular Neuroscience. 10: 417. PMID 29311810 DOI: 10.3389/Fnmol.2017.00417  0.566
2017 Piccirilli F, Plotegher N, Ortore MG, Tessari I, Brucale M, Spinozzi F, Beltramini M, Mariani P, Militello V, Lupi S, Perucchi A, Bubacco L. High-Pressure-Driven Reversible Dissociation of α-Synuclein Fibrils Reveals Structural Hierarchy. Biophysical Journal. 113: 1685-1696. PMID 29045863 DOI: 10.1016/J.Bpj.2017.08.042  0.334
2017 Biosa A, Sandrelli F, Beltramini M, Greggio E, Bubacco L, Bisaglia M. Recent findings on the physiological function of DJ-1: Beyond Parkinson's disease. Neurobiology of Disease. 108: 65-72. PMID 28823929 DOI: 10.1016/J.Nbd.2017.08.005  0.351
2017 Piccirilli F, Plotegher N, Spinozzi F, Bubacco L, Mariani P, Beltramini M, Tessari I, Militello V, Perucchi A, Amenitsch H, Baldassarri E, Steinhart M, Lupi S, Ortore MG. Pressure effects on α-synuclein amyloid fibrils: An experimental investigation on their dissociation and reversible nature. Archives of Biochemistry and Biophysics. 627: 46-55. PMID 28624352 DOI: 10.1016/J.Abb.2017.06.007  0.346
2017 Ramírez MB, Ordóñez AJL, Fdez E, Madero-Pérez J, Gonnelli A, Drouyer M, Chartier-Harlin MC, Taymans JM, Bubacco L, Greggio E, Hilfiker S. GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2. Human Molecular Genetics. 26: 2747-2767. PMID 28453723 DOI: 10.1093/Hmg/Ddx161  0.375
2017 Civiero L, Russo I, Bubacco L, Greggio E. Molecular Insights and Functional Implication of LRRK2 Dimerization. Advances in Neurobiology. 14: 107-121. PMID 28353281 DOI: 10.1007/978-3-319-49969-7_6  0.365
2017 Longo F, Mercatelli D, Novello S, Arcuri L, Brugnoli A, Vincenzi F, Russo I, Berti G, Mabrouk OS, Kennedy RT, Shimshek DR, Varani K, Bubacco L, Greggio E, Morari M. Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice. Acta Neuropathologica Communications. 5: 22. PMID 28292328 DOI: 10.1186/S40478-017-0426-8  0.531
2017 Ferrari E, Capucciati A, Prada I, Zucca FA, D'Arrigo G, Pontiroli D, Bridelli MG, Sturini M, Bubacco L, Monzani E, Verderio C, Zecca L, Casella L. Synthesis, Structure Characterization, and Evaluation in Microglia Cultures of Neuromelanin Analogues Suitable for Modeling Parkinson's Disease. Acs Chemical Neuroscience. 8: 501-512. PMID 28292181 DOI: 10.1021/Acschemneuro.6B00231  0.364
2017 Greggio E, Bubacco L, Russo I. Cross-talk between LRRK2 and PKA: implication for Parkinson's disease? Biochemical Society Transactions. 45: 261-267. PMID 28202680 DOI: 10.1042/Bst20160396  0.389
2017 Plotegher N, Berti G, Ferrari E, Tessari I, Zanetti M, Lunelli L, Greggio E, Bisaglia M, Veronesi M, Girotto S, Dalla Serra M, Perego C, Casella L, Bubacco L. DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function. Scientific Reports. 7: 40699. PMID 28084443 DOI: 10.1038/Srep40699  0.355
2016 Cartelli D, Aliverti A, Barbiroli A, Santambrogio C, Ragg EM, Casagrande FV, Cantele F, Beltramone S, Marangon J, De Gregorio C, Pandini V, Emanuele M, Chieregatti E, Pieraccini S, Holmqvist S, ... Bubacco L, et al. α-Synuclein is a Novel Microtubule Dynamase. Scientific Reports. 6: 33289. PMID 27628239 DOI: 10.1038/Srep33289  0.368
2016 Ferrazza R, Cogo S, Melrose H, Bubacco L, Greggio E, Guella G, Civiero L, Plotegher N. LRRK2 deficiency impacts ceramide metabolism in brain. Biochemical and Biophysical Research Communications. 478: 1141-6. PMID 27539321 DOI: 10.1016/J.Bbrc.2016.08.082  0.361
2016 Filograna R, Godena VK, Sanchez-Martinez A, Ferrari E, Casella L, Beltramini M, Bubacco L, Whitworth AJ, Bisaglia M. SOD-mimetic M40403 is protective in cell and fly models of paraquat toxicity: Implications for Parkinson disease. The Journal of Biological Chemistry. PMID 26953346 DOI: 10.1074/Jbc.M115.708057  0.342
2016 Belluzzi E, Gonnelli A, Cirnaru MD, Marte A, Plotegher N, Russo I, Civiero L, Cogo S, Carrion MP, Franchin C, Arrigoni G, Beltramini M, Bubacco L, Onofri F, Piccoli G, et al. LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate. Molecular Neurodegeneration. 11: 1. PMID 26758690 DOI: 10.1186/S13024-015-0066-Z  0.352
2016 Plotegher N, Bubacco L. Lysines, Achilles' heel in alpha-synuclein conversion to a deadly neuronal endotoxin. Ageing Research Reviews. 26: 62-71. PMID 26690800 DOI: 10.1016/J.Arr.2015.12.002  0.356
2016 Filograna R, Beltramini M, Bubacco L, Bisaglia M. Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View. Current Neuropharmacology. 14: 260-71. PMID 26517052 DOI: 10.2174/1570159X13666151030102718  0.343
2015 Russo I, Berti G, Plotegher N, Bernardo G, Filograna R, Bubacco L, Greggio E. Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells. Journal of Neuroinflammation. 12: 230. PMID 26646749 DOI: 10.1186/S12974-015-0449-7  0.365
2015 Civiero L, Cirnaru MD, Beilina A, Rodella U, Russo I, Belluzzi E, Lobbestael E, Reyniers L, Hondhamuni G, Lewis PA, Van den Haute C, Baekelandt V, Bandopadhyay R, Bubacco L, Piccoli G, et al. Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain. Journal of Neurochemistry. PMID 26375402 DOI: 10.1111/Jnc.13369  0.558
2015 Plotegher N, Stringari C, Jahid S, Veronesi M, Girotto S, Gratton E, Bubacco L. NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2484-94. PMID 25713058 DOI: 10.1096/Fj.14-260281  0.346
2015 Sivanesam K, Byrne A, Bisaglia M, Bubacco L, Andersen N. Binding Interactions of Agents That Alter α-Synuclein Aggregation. Rsc Advances. 5: 11577-11590. PMID 25705374 DOI: 10.1039/C5Ra00325C  0.329
2015 Ruzza P, Gazziero M, Marchi MD, Massalongo G, Marchiani A, Autiero I, Tessari I, Bubacco L, Calderan A. Peptides as modulators of α-synuclein aggregation. Protein and Peptide Letters. 22: 354-61. PMID 25666040 DOI: 10.2174/0929866522666150209142649  0.362
2015 De Ricco R, Valensin D, Dell'Acqua S, Casella L, Gaggelli E, Valensin G, Bubacco L, Mangani S. Differences in the binding of copper(I) to α- and β-synuclein. Inorganic Chemistry. 54: 265-72. PMID 25495902 DOI: 10.1021/Ic502407W  0.417
2014 Vicario M, Zagari A, Granata V, Munari F, Mammi S, Bubacco L, Skaper SD, Negro A. A novel prion protein-tyrosine hydroxylase interaction. Cns & Neurological Disorders Drug Targets. 13: 896-908. PMID 25012618 DOI: 10.2174/1871527313666140711092955  0.344
2014 Cirnaru MD, Marte A, Belluzzi E, Russo I, Gabrielli M, Longo F, Arcuri L, Murru L, Bubacco L, Matteoli M, Fedele E, Sala C, Passafaro M, Morari M, Greggio E, et al. LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex. Frontiers in Molecular Neuroscience. 7: 49. PMID 24904275 DOI: 10.3389/Fnmol.2014.00049  0.54
2014 Plotegher N, Kumar D, Tessari I, Brucale M, Munari F, Tosatto L, Belluzzi E, Greggio E, Bisaglia M, Capaldi S, Aioanei D, Mammi S, Monaco HL, Samo B, Bubacco L. The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity. Human Molecular Genetics. 23: 5615-29. PMID 24895406 DOI: 10.1093/Hmg/Ddu275  0.391
2014 Russo I, Bubacco L, Greggio E. LRRK2 and neuroinflammation: partners in crime in Parkinson's disease? Journal of Neuroinflammation. 11: 52. PMID 24655756 DOI: 10.1186/1742-2094-11-52  0.379
2014 Girotto S, Cendron L, Bisaglia M, Tessari I, Mammi S, Zanotti G, Bubacco L. DJ-1 is a copper chaperone acting on SOD1 activation. The Journal of Biological Chemistry. 289: 10887-99. PMID 24567322 DOI: 10.1074/Jbc.M113.535112  0.379
2014 Plotegher N, Gratton E, Bubacco L. Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells Biochimica Et Biophysica Acta - General Subjects. 1840: 2014-2024. PMID 24561157 DOI: 10.1016/J.Bbagen.2014.02.013  0.341
2014 Plotegher N, Greggio E, Bisaglia M, Bubacco L. Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity. Quarterly Reviews of Biophysics. 47: 1-48. PMID 24443929 DOI: 10.1017/S0033583513000097  0.365
2014 Bisaglia M, Filograna R, Beltramini M, Bubacco L. Are dopamine derivatives implicated in the pathogenesis of Parkinson's disease? Ageing Research Reviews. 13: 107-14. PMID 24389159 DOI: 10.1016/J.Arr.2013.12.009  0.394
2014 Ruzza P, Siligardi G, Hussain R, Marchiani A, Islami M, Bubacco L, Delogu G, Fabbri D, Dettori MA, Sechi M, Pala N, Spissu Y, Migheli R, Serra PA, Sechi G. Ceftriaxone blocks the polymerization of α-synuclein and exerts neuroprotective effects in vitro Acs Chemical Neuroscience. 5: 30-38. PMID 24099687 DOI: 10.1021/Cn400149K  0.407
2014 Plotegher N, Stringari C, Jahid S, Gratton E, Bubacco L. NADH is an Endogenous Reporter for Alpha-Synuclein Aggregation in Live Cells Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.392  0.333
2013 Fecchio C, De Franceschi G, Relini A, Greggio E, Dalla Serra M, Bubacco L, Polverino de Laureto P. α-Synuclein oligomers induced by docosahexaenoic acid affect membrane integrity. Plos One. 8: e82732. PMID 24312431 DOI: 10.1371/Journal.Pone.0082732  0.338
2013 Marchiani A, Mammi S, Siligardi G, Hussain R, Tessari I, Bubacco L, Delogu G, Fabbri D, Dettori MA, Sanna D, Dedola S, Serra PA, Ruzza P. Small molecules interacting with α-synuclein: antiaggregating and cytoprotective properties. Amino Acids. 45: 327-38. PMID 23645386 DOI: 10.1007/S00726-013-1503-3  0.356
2013 Bisaglia M, Greggio E, Beltramini M, Bubacco L. Dysfunction of dopamine homeostasis: clues in the hunt for novel Parkinson's disease therapies. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2101-10. PMID 23463698 DOI: 10.1096/Fj.12-226852  0.356
2013 Codolo G, Plotegher N, Pozzobon T, Brucale M, Tessari I, Bubacco L, de Bernard M. Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies. Plos One. 8: e55375. PMID 23383169 DOI: 10.1371/Journal.Pone.0055375  0.359
2013 Camponeschi F, Valensin D, Tessari I, Bubacco L, Dell'Acqua S, Casella L, Monzani E, Gaggelli E, Valensin G. Copper(I)-α-synuclein interaction: structural description of two independent and competing metal binding sites. Inorganic Chemistry. 52: 1358-67. PMID 23343468 DOI: 10.1021/Ic302050M  0.351
2013 Biosa A, Trancikova A, Civiero L, Glauser L, Bubacco L, Greggio E, Moore DJ. GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2. Human Molecular Genetics. 22: 1140-56. PMID 23241358 DOI: 10.1093/Hmg/Dds522  0.352
2012 Pivato M, De Franceschi G, Tosatto L, Frare E, Kumar D, Aioanei D, Brucale M, Tessari I, Bisaglia M, Samori B, de Laureto PP, Bubacco L. Covalent α-synuclein dimers: chemico-physical and aggregation properties. Plos One. 7: e50027. PMID 23272053 DOI: 10.1371/Journal.Pone.0050027  0.37
2012 Civiero L, Bubacco L. Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions? Biochemical Society Transactions. 40: 1095-101. PMID 22988872 DOI: 10.1042/Bst20120123  0.371
2012 Civiero L, Vancraenenbroeck R, Belluzzi E, Beilina A, Lobbestael E, Reyniers L, Gao F, Micetic I, De Maeyer M, Bubacco L, Baekelandt V, Cookson MR, Greggio E, Taymans JM. Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers. Plos One. 7: e43472. PMID 22952686 DOI: 10.1371/Journal.Pone.0043472  0.58
2012 Tosatto L, Andrighetti AO, Plotegher N, Antonini V, Tessari I, Ricci L, Bubacco L, Dalla Serra M. Alpha-synuclein pore forming activity upon membrane association Biochimica Et Biophysica Acta - Biomembranes. 1818: 2876-2883. PMID 22820150 DOI: 10.1016/J.Bbamem.2012.07.007  0.37
2012 Belluzzi E, Bisaglia M, Lazzarini E, Tabares LC, Beltramini M, Bubacco L. Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's disease. Plos One. 7: e38026. PMID 22723845 DOI: 10.1371/Journal.Pone.0038026  0.376
2012 Greggio E, Civiero L, Bisaglia M, Bubacco L. Parkinson's disease and immune system: is the culprit LRRKing in the periphery? Journal of Neuroinflammation. 9: 94. PMID 22594666 DOI: 10.1186/1742-2094-9-94  0.331
2012 Girotto S, Sturlese M, Bellanda M, Tessari I, Cappellini R, Bisaglia M, Bubacco L, Mammi S. Dopamine-derived quinones affect the structure of the redox sensor DJ-1 through modifications at Cys-106 and Cys-53. The Journal of Biological Chemistry. 287: 18738-49. PMID 22431735 DOI: 10.1074/Jbc.M111.311589  0.376
2012 Civiero L, Lobbestael E, Gao F, Beilina A, Reyniers L, Vancraenenbroeck R, Belluzzi E, Micetic I, Maeyer MD, Bubacco L, Baekelandt V, Cookson M, Taymans J, Greggio E. Electron microscopy analysis of purified LRRK1 and LRRK2 demonstrates formation of dimers F1000research. 3. DOI: 10.7490/F1000Research.1090051.1  0.483
2011 Huggins KN, Bisaglia M, Bubacco L, Tatarek-Nossol M, Kapurniotu A, Andersen NH. Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state. Biochemistry. 50: 8202-12. PMID 21848289 DOI: 10.1021/Bi200760H  0.33
2011 De Franceschi G, Frare E, Pivato M, Relini A, Penco A, Greggio E, Bubacco L, Fontana A, de Laureto PP. Structural and morphological characterization of aggregated species of α-synuclein induced by docosahexaenoic acid. The Journal of Biological Chemistry. 286: 22262-74. PMID 21527634 DOI: 10.1074/Jbc.M110.202937  0.401
2011 Greggio E, Bisaglia M, Civiero L, Bubacco L. Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease? Molecular Neurodegeneration. 6: 6. PMID 21244648 DOI: 10.1186/1750-1326-6-6  0.425
2010 Bortolus M, Bisaglia M, Zoleo A, Fittipaldi M, Benfatto M, Bubacco L, Maniero AL. Structural characterization of a high affinity mononuclear site in the copper(II)-α-synuclein complex. Journal of the American Chemical Society. 132: 18057-66. PMID 21141829 DOI: 10.1021/Ja103338N  0.353
2010 Bisaglia M, Soriano ME, Arduini I, Mammi S, Bubacco L. Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: implications for mitochondrial dysfunction in Parkinson disease. Biochimica Et Biophysica Acta. 1802: 699-706. PMID 20600874 DOI: 10.1016/J.Bbadis.2010.06.006  0.357
2010 Bisaglia M, Greggio E, Maric D, Miller DW, Cookson MR, Bubacco L. Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells. Bmc Neuroscience. 11: 41. PMID 20334701 DOI: 10.1186/1471-2202-11-41  0.563
2010 Bisaglia M, Tosatto L, Munari F, Tessari I, de Laureto PP, Mammi S, Bubacco L. Dopamine quinones interact with α-synuclein to form unstructured adducts Biochemical and Biophysical Research Communications. 394: 424-428. PMID 20226175 DOI: 10.1016/J.Bbrc.2010.03.044  0.395
2010 Tosatto L, Plotegher N, Tessari I, Bisaglia M, Bubacco L, Serra MD. Insights on Channel-Like Activity of Membrane Bound Alpha-Synuclein Biophysical Journal. 98: 1-9. DOI: 10.1016/J.Bpj.2009.12.606  0.371
2009 De Franceschi G, Frare E, Bubacco L, Mammi S, Fontana A, de Laureto PP. Molecular insights into the interaction between alpha-synuclein and docosahexaenoic acid. Journal of Molecular Biology. 394: 94-107. PMID 19747490 DOI: 10.1016/J.Jmb.2009.09.008  0.379
2009 Bisaglia M, Tessari I, Mammi S, Bubacco L. Interaction between alpha-synuclein and metal ions, still looking for a role in the pathogenesis of Parkinson's disease. Neuromolecular Medicine. 11: 239-51. PMID 19669606 DOI: 10.1007/S12017-009-8082-1  0.321
2009 Brucale M, Sandal M, Di Maio S, Rampioni A, Tessari I, Tosatto L, Bisaglia M, Bubacco L, Samorì B. Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers. Chembiochem : a European Journal of Chemical Biology. 10: 176-83. PMID 19067456 DOI: 10.1002/Cbic.200800581  0.343
2009 Bisaglia M, Mammi S, Bubacco L. Structural insights on physiological functions and pathological effects of alpha-synuclein. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 329-40. PMID 18948383 DOI: 10.1096/Fj.08-119784  0.354
2009 Arduini I, Soriano ME, Bisaglia M, Bernardi P, Bubacco L. P3.083 Dopamine oxidation products as mitochondrial endotoxins, a potential molecular mechanism for selective neurodegeneration in Parkinson disease Parkinsonism & Related Disorders. 15. DOI: 10.1016/S1353-8020(09)70647-9  0.322
2009 Bisaglia M, Greggio E, Tosatto L, Munari F, Maric D, Tessari I, Polverino de Laureto P, Miller D, Mammi S, Cookson M, Bubacco L. P3.002 Modiflcation by dopamine adducts links a-synuclein to oxidative stress in Parkinson's disease Parkinsonism & Related Disorders. 15: S148. DOI: 10.1016/S1353-8020(09)70566-8  0.535
2008 Tessari I, Bisaglia M, Valle F, Samorì B, Bergantino E, Mammi S, Bubacco L. The reaction of alpha-synuclein with tyrosinase: possible implications for Parkinson disease. The Journal of Biological Chemistry. 283: 16808-17. PMID 18390556 DOI: 10.1074/Jbc.M709014200  0.377
2008 Campello S, Beltramini M, Giordano G, Di Muro P, Marino SM, Bubacco L. Role of the tertiary structure in the diphenol oxidase activity of Octopus vulgaris hemocyanin. Archives of Biochemistry and Biophysics. 471: 159-67. PMID 18237542 DOI: 10.1016/J.Abb.2008.01.006  0.319
2008 Sandal M, Valle F, Tessari I, Mammi S, Bergantino E, Musiani F, Brucale M, Bubacco L, Samorì B. Conformational equilibria in monomeric alpha-synuclein at the single-molecule level. Plos Biology. 6: e6. PMID 18198943 DOI: 10.1371/Journal.Pbio.0060006  0.354
2007 Bisaglia M, Mammi S, Bubacco L. Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with alpha-synuclein. The Journal of Biological Chemistry. 282: 15597-605. PMID 17395592 DOI: 10.1074/Jbc.M610893200  0.375
2006 Bisaglia M, Trolio A, Bellanda M, Bergantino E, Bubacco L, Mammi S. Structure and topology of the non-amyloid-beta component fragment of human alpha-synuclein bound to micelles: implications for the aggregation process. Protein Science : a Publication of the Protein Society. 15: 1408-16. PMID 16731975 DOI: 10.1110/Ps.052048706  0.344
2005 Greggio E, Bergantino E, Carter D, Ahmad R, Costin GE, Hearing VJ, Clarimon J, Singleton A, Eerola J, Hellström O, Tienari PJ, Miller DW, Beilina A, Bubacco L, Cookson MR. Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease. Journal of Neurochemistry. 93: 246-56. PMID 15773923 DOI: 10.1111/J.1471-4159.2005.03019.X  0.568
2005 Tepper AW, Bubacco L, Canters GW. Interaction between the type-3 copper protein tyrosinase and the substrate analogue p-nitrophenol studied by NMR. Journal of the American Chemical Society. 127: 567-75. PMID 15643881 DOI: 10.1021/Ja0454687  0.318
2005 Bisaglia M, Tessari I, Pinato L, Bellanda M, Giraudo S, Fasano M, Bergantino E, Bubacco L, Mammi S. A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles. Biochemistry. 44: 329-39. PMID 15628875 DOI: 10.1021/Bi048448Q  0.328
2005 Bisaglia M, Trolio A, Tessari I, Bubacco L, Mammi S, Bergantino E. Cloning, expression, purification, and spectroscopic analysis of the fragment 57-102 of human alpha-synuclein. Protein Expression and Purification. 39: 90-6. PMID 15596364 DOI: 10.1016/J.Pep.2004.09.018  0.35
2004 Bubacco L, van Gastel M, Benfatto M, Tepper AW, Canters GW. What are the structural features of the active site that define binuclear copper proteins function? Micron (Oxford, England : 1993). 35: 143-5. PMID 15036320 DOI: 10.1016/J.Micron.2003.10.046  0.326
2004 Gatto S, De Filippis V, Spinozzi F, Di Muro P, Bubacco L, Beltramini M. Structural role of the copper ions in the dinuclear active site of Carcinus aestuarii hemocyanin. Micron (Oxford, England : 1993). 35: 43-4. PMID 15036286 DOI: 10.1016/J.Micron.2003.10.011  0.307
2003 Bubacco L, Van Gastel M, Groenen EJ, Vijgenboom E, Canters GW. Spectroscopic characterization of the electronic changes in the active site of Streptomyces antibioticus tyrosinase upon binding of transition state analogue inhibitors. The Journal of Biological Chemistry. 278: 7381-9. PMID 12473668 DOI: 10.1074/Jbc.M206394200  0.321
2002 Tepper AW, Bubacco L, Canters GW. Structural basis and mechanism of the inhibition of the type-3 copper protein tyrosinase from Streptomyces antibioticus by halide ions. The Journal of Biological Chemistry. 277: 30436-44. PMID 12048185 DOI: 10.1074/Jbc.M202461200  0.318
1998 Zlateva T, Santagostini L, Bubacco L, Casella L, Salvato B, Beltramini M. Isolation of the met-derivative intermediate in the catalase-like activity of deoxygenated Octopus vulgaris hemocyanin Journal of Inorganic Biochemistry. 72: 211-215. DOI: 10.1016/S0162-0134(98)10082-X  0.302
1997 Alzuet G, Bubacco L, Casella L, Rocco GP, Salvato B, Beltramini M. The binding of azide to copper-containing and cobalt-containing forms of hemocyanin from the mediterranean crab Carcinus aestuarii. European Journal of Biochemistry. 247: 688-94. PMID 9266714 DOI: 10.1111/J.1432-1033.1997.00688.X  0.319
1995 Magliozzo RS, Bubacco L, McCracken J, Jiang F, Beltramini M, Salvato B, Peisach J. Cu(II) coordination in arthropod and mollusk green half-methemocyanins analyzed by electron spin-echo envelope modulation spectroscopy. Biochemistry. 34: 1513-23. PMID 7849010 DOI: 10.1021/Bi00005A007  0.308
1995 Beltramini M, Bubacco L, Casella L, Alzuet G, Gullotti M, Salvato B. The oxidation of hemocyanin. Kinetics, reaction mechanism and characterization of met-hemocyanin product. European Journal of Biochemistry. 232: 98-105. PMID 7556177 DOI: 10.1111/J.1432-1033.1995.Tb20786.X  0.315
1992 Ricchelli F, Beltramini M, Bubacco L, Salvato B, Filippi B. Circular dichroism and fluorescence studies to probe the conformational properties of Rhus vernicifera laccase Inorganica Chimica Acta. 193: 237-243. DOI: 10.1016/S0020-1693(00)80358-8  0.314
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