Jan Krzysztof Blusztajn, Ph.D. - Publications

Boston University, Boston, MA, United States 

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Mellott TJ, Huleatt OM, Shade BN, Pender SM, Liu YB, Slack BE, Blusztajn JK. Correction: Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. Plos One. 12: e0174875. PMID 28334015 DOI: 10.1371/journal.pone.0174875  0.64
2017 Mellott TJ, Huleatt OM, Shade BN, Pender SM, Liu YB, Slack BE, Blusztajn JK. Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. Plos One. 12: e0170450. PMID 28103298 DOI: 10.1371/journal.pone.0170450  0.64
2015 Langley EA, Krykbaeva M, Blusztajn JK, Mellott TJ. High maternal choline consumption during pregnancy and nursing alleviates deficits in social interaction and improves anxiety-like behaviors in the BTBR T+Itpr3tf/J mouse model of autism. Behavioural Brain Research. 278: 210-20. PMID 25300468 DOI: 10.1016/j.bbr.2014.09.043  0.64
2014 Mellott TJ, Pender SM, Burke RM, Langley EA, Blusztajn JK. IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. Plos One. 9: e94287. PMID 24732467 DOI: 10.1371/journal.pone.0094287  0.64
2013 Burke RM, Norman TA, Haydar TF, Slack BE, Leeman SE, Blusztajn JK, Mellott TJ. BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 19567-72. PMID 24218590 DOI: 10.1073/pnas.1319297110  0.64
2013 Blusztajn JK, Mellott TJ. Neuroprotective actions of perinatal choline nutrition. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 51: 591-9. PMID 23314544 DOI: 10.1515/cclm-2012-0635  0.64
2012 Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, ... ... Blusztajn JK, et al. Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model. Science Translational Medicine. 4: 134ra60. PMID 22593173 DOI: 10.1126/scitranslmed.3003716  0.64
2012 Blusztajn JK, Mellott TJ. Choline nutrition programs brain development via DNA and histone methylation. Central Nervous System Agents in Medicinal Chemistry. 12: 82-94. PMID 22483275  0.64
2011 Wong-Goodrich SJ, Tognoni CM, Mellott TJ, Glenn MJ, Blusztajn JK, Williams CL. Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood. Brain Research. 1413: 84-97. PMID 21840511 DOI: 10.1016/j.brainres.2011.07.042  0.64
2011 Lopez-Coviella I, Mellott TJ, Schnitzler AC, Blusztajn JK. BMP9 protects septal neurons from axotomy-evoked loss of cholinergic phenotype. Plos One. 6: e21166. PMID 21695154 DOI: 10.1371/journal.pone.0021166  0.64
2011 Carey RM, Blusztajn JK, Slack BE. Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin. Bmc Cell Biology. 12: 20. PMID 21586144 DOI: 10.1186/1471-2121-12-20  0.64
2011 Wong-Goodrich SJ, Glenn MJ, Mellott TJ, Liu YB, Blusztajn JK, Williams CL. Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood. Hippocampus. 21: 584-608. PMID 20232399 DOI: 10.1002/hipo.20783  0.64
2010 Crivello NA, Blusztajn JK, Joseph JA, Shukitt-Hale B, Smith DE. Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age. Nutrition Research (New York, N.Y.). 30: 722-30. PMID 21056288 DOI: 10.1016/j.nutres.2010.09.008  0.64
2010 Schnitzler AC, Mellott TJ, Lopez-Coviella I, Tallini YN, Kotlikoff MI, Follettie MT, Blusztajn JK. BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8221-8. PMID 20554873 DOI: 10.1523/JNEUROSCI.5611-09.2010  0.64
2010 Johnson AR, Craciunescu CN, Guo Z, Teng YW, Thresher RJ, Blusztajn JK, Zeisel SH. Deletion of murine choline dehydrogenase results in diminished sperm motility. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2752-61. PMID 20371614 DOI: 10.1096/fj.09-153718  0.64
2009 Kovacheva VP, Davison JM, Mellott TJ, Rogers AE, Yang S, O'Brien MJ, Blusztajn JK. Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1054-63. PMID 19047067 DOI: 10.1096/fj.08-122168  0.64
2009 Davison JM, Mellott TJ, Kovacheva VP, Blusztajn JK. Gestational choline supply regulates methylation of histone H3, expression of histone methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA methylation of their genes in rat fetal liver and brain. The Journal of Biological Chemistry. 284: 1982-9. PMID 19001366 DOI: 10.1074/jbc.M807651200  0.64
2008 Schnitzler AC, Lopez-Coviella I, Blusztajn JK. Differential modulation of nerve growth factor receptor (p75) and cholinergic gene expression in purified p75-expressing and non-expressing basal forebrain neurons by BMP9. Brain Research. 1246: 19-28. PMID 18952073 DOI: 10.1016/j.brainres.2008.09.085  0.64
2008 Madziar B, Shah S, Brock M, Burke R, Lopez-Coviella I, Nickel AC, Cakal EB, Blusztajn JK, Berse B. Nerve growth factor regulates the expression of the cholinergic locus and the high-affinity choline transporter via the Akt/PKB signaling pathway. Journal of Neurochemistry. 107: 1284-93. PMID 18793330 DOI: 10.1111/j.1471-4159.2008.05681.x  0.64
2008 Napoli I, Blusztajn JK, Mellott TJ. Prenatal choline supplementation in rats increases the expression of IGF2 and its receptor IGF2R and enhances IGF2-induced acetylcholine release in hippocampus and frontal cortex. Brain Research. 1237: 124-35. PMID 18786520 DOI: 10.1016/j.brainres.2008.08.046  0.64
2008 Glenn MJ, Kirby ED, Gibson EM, Wong-Goodrich SJ, Mellott TJ, Blusztajn JK, Williams CL. Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats. Brain Research. 1237: 110-23. PMID 18786518 DOI: 10.1016/j.brainres.2008.08.049  0.64
2008 Wong-Goodrich SJ, Glenn MJ, Mellott TJ, Blusztajn JK, Meck WH, Williams CL. Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero. Brain Research. 1237: 153-66. PMID 18778697 DOI: 10.1016/j.brainres.2008.08.074  0.64
2008 Wong-Goodrich SJ, Mellott TJ, Glenn MJ, Blusztajn JK, Williams CL. Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus. Neurobiology of Disease. 30: 255-69. PMID 18353663 DOI: 10.1016/j.nbd.2008.01.008  0.64
2008 Slack BE, Blusztajn JK. Differential regulation of mTOR-dependent S6 phosphorylation by muscarinic acetylcholine receptor subtypes. Journal of Cellular Biochemistry. 104: 1818-31. PMID 18348264 DOI: 10.1002/jcb.21745  0.64
2008 Schnitzler AC, Lopez-Coviella I, Blusztajn JK. Purification and culture of nerve growth factor receptor (p75)-expressing basal forebrain cholinergic neurons. Nature Protocols. 3: 34-40. PMID 18193019 DOI: 10.1038/nprot.2007.477  0.64
2007 Meck WH, Williams CL, Cermak JM, Blusztajn JK. Developmental periods of choline sensitivity provide an ontogenetic mechanism for regulating memory capacity and age-related dementia. Frontiers in Integrative Neuroscience. 1: 7. PMID 18958235 DOI: 10.3389/neuro.07.007.2007  0.64
2007 Kovacheva VP, Mellott TJ, Davison JM, Wagner N, Lopez-Coviella I, Schnitzler AC, Blusztajn JK. Gestational choline deficiency causes global and Igf2 gene DNA hypermethylation by up-regulation of Dnmt1 expression. The Journal of Biological Chemistry. 282: 31777-88. PMID 17724018 DOI: 10.1074/jbc.M705539200  0.64
2007 Yaar M, Zhai S, Panova I, Fine RE, Eisenhauer PB, Blusztajn JK, Lopez-Coviella I, Gilchrest BA. A cyclic peptide that binds p75(NTR) protects neurones from beta amyloid (1-40)-induced cell death. Neuropathology and Applied Neurobiology. 33: 533-43. PMID 17596181 DOI: 10.1111/j.1365-2990.2007.00844.x  0.64
2007 Glenn MJ, Gibson EM, Kirby ED, Mellott TJ, Blusztajn JK, Williams CL. Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats. The European Journal of Neuroscience. 25: 2473-82. PMID 17445242 DOI: 10.1111/j.1460-9568.2007.05505.x  0.64
2007 Mellott TJ, Kowall NW, Lopez-Coviella I, Blusztajn JK. Prenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats. Brain Research. 1151: 1-11. PMID 17399691 DOI: 10.1016/j.brainres.2007.03.004  0.64
2007 Brock M, Nickel AC, Madziar B, Blusztajn JK, Berse B. Differential regulation of the high affinity choline transporter and the cholinergic locus by cAMP signaling pathways. Brain Research. 1145: 1-10. PMID 17320829 DOI: 10.1016/j.brainres.2007.01.119  0.64
2007 Mellott TJ, Follettie MT, Diesl V, Hill AA, Lopez-Coviella I, Blusztajn JK. Prenatal choline availability modulates hippocampal and cerebral cortical gene expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1311-23. PMID 17264169 DOI: 10.1096/fj.06-6597com  0.64
2006 Lopez-Coviella I, Mellott TM, Kovacheva VP, Berse B, Slack BE, Zemelko V, Schnitzler A, Blusztajn JK. Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain. Brain Research. 1088: 49-56. PMID 16626664 DOI: 10.1016/j.brainres.2006.02.073  0.64
2006 Durcan N, Costello RW, McLean WG, Blusztajn J, Madziar B, Fenech AG, Hall IP, Gleich GJ, McGarvey L, Walsh MT. Eosinophil-mediated cholinergic nerve remodeling. American Journal of Respiratory Cell and Molecular Biology. 34: 775-86. PMID 16456188 DOI: 10.1165/rcmb.2005-0196OC  0.64
2006 Slack BE, Siniaia MS, Blusztajn JK. Collagen type I selectively activates ectodomain shedding of the discoidin domain receptor 1: involvement of Src tyrosine kinase. Journal of Cellular Biochemistry. 98: 672-84. PMID 16440311 DOI: 10.1002/jcb.20812  0.64
2005 Berse B, Szczecinska W, Lopez-Coviella I, Madziar B, Zemelko V, Kaminski R, Kozar K, Lips KS, Pfeil U, Blusztajn JK. Expression of high affinity choline transporter during mouse development in vivo and its upregulation by NGF and BMP-4 in vitro. Brain Research. Developmental Brain Research. 157: 132-40. PMID 15885806 DOI: 10.1016/j.devbrainres.2005.03.013  0.64
2005 Lopez-Coviella I, Follettie MT, Mellott TJ, Kovacheva VP, Slack BE, Diesl V, Berse B, Thies RS, Blusztajn JK. Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 102: 6984-9. PMID 15870197 DOI: 10.1073/pnas.0502097102  0.64
2005 Kaczmarek E, Erb L, Koziak K, Jarzyna R, Wink MR, Guckelberger O, Blusztajn JK, Trinkaus-Randall V, Weisman GA, Robson SC. Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways. Thrombosis and Haemostasis. 93: 735-42. PMID 15841322 DOI: 10.1267/THRO05040735  0.64
2004 Brandon EP, Mellott T, Pizzo DP, Coufal N, D'Amour KA, Gobeske K, Lortie M, López-Coviella I, Berse B, Thal LJ, Gage FH, Blusztajn JK. Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5459-66. PMID 15201317 DOI: 10.1523/JNEUROSCI.1106-04.2004  0.64
2004 Mellott TJ, Williams CL, Meck WH, Blusztajn JK. Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 545-7. PMID 14715695 DOI: 10.1096/fj.03-0877fje  0.64
2003 Schueler UH, Kolter T, Kaneski CR, Blusztajn JK, Herkenham M, Sandhoff K, Brady RO. Toxicity of glucosylsphingosine (glucopsychosine) to cultured neuronal cells: a model system for assessing neuronal damage in Gaucher disease type 2 and 3. Neurobiology of Disease. 14: 595-601. PMID 14678774 DOI: 10.1016/j.nbd.2003.08.016  0.64
2003 Song P, Sekhon HS, Proskocil B, Blusztajn JK, Mark GP, Spindel ER. Synthesis of acetylcholine by lung cancer. Life Sciences. 72: 2159-68. PMID 12628474 DOI: 10.1016/S0024-3205(03)00078-X  0.64
2003 Song P, Sekhon HS, Jia Y, Keller JA, Blusztajn JK, Mark GP, Spindel ER. Acetylcholine is synthesized by and acts as an autocrine growth factor for small cell lung carcinoma. Cancer Research. 63: 214-21. PMID 12517800  0.64
2002 Mellott T, Lopez-Coviella I, Blusztajn JK, Berse B. Mitogen-activated protein kinase kinase negatively modulates ciliary neurotrophic factor-activated choline acetyltransferase gene expression. European Journal of Biochemistry / Febs. 269: 850-8. PMID 11846786 DOI: 10.1046/j.0014-2956.2001.02717.x  0.64
2002 Holmes GL, Yang Y, Liu Z, Cermak JM, Sarkisian MR, Stafstrom CE, Neill JC, Blusztajn JK. Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus. Epilepsy Research. 48: 3-13. PMID 11823105 DOI: 10.1016/S0920-1211(01)00321-7  0.64
2002 Guo-Ross SX, Clark S, Montoya DA, Jones KH, Obernier J, Shetty AK, White AM, Blusztajn JK, Wilson WA, Swartzwelder HS. Prenatal choline supplementation protects against postnatal neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: RC195. PMID 11756524  0.64
2001 López-Coviella I, Blusztajn JK. [Bone morphogenetic proteins and cholinergic neurons in the central nervous system]. Revista De Neurologia. 33: 1054-60. PMID 11785034  0.64
2001 Zhao D, Frohman MA, Blusztajn JK. Generation of choline for acetylcholine synthesis by phospholipase D isoforms. Bmc Neuroscience. 2: 16. PMID 11734063 DOI: 10.1186/1471-2202-2-16  0.64
2001 Martínez-Morales JR, López-Coviella I, Hernández-Jiménez JG, Reyes R, Bello AR, Hernández G, Blusztajn JK, Alonso R. Sex steroids modulate luteinizing hormone-releasing hormone secretion in a cholinergic cell line from the basal forebrain. Neuroscience. 103: 1025-31. PMID 11301209 DOI: 10.1016/S0306-4522(01)00023-9  0.64
2000 Malik MA, Blusztajn JK, Greenwood CE. Nutrients as trophic factors in neurons and the central nervous system: role of retinoic acid. The Journal of Nutritional Biochemistry. 11: 2-13. PMID 15539337 DOI: 10.1016/S0955-2863(99)00066-2  0.64
2000 Yang Y, Liu Z, Cermak JM, Tandon P, Sarkisian MR, Stafstrom CE, Neill JC, Blusztajn JK, Holmes GL. Protective effects of prenatal choline supplementation on seizure-induced memory impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC109. PMID 11069978  0.64
2000 Montoya DA, White AM, Williams CL, Blusztajn JK, Meck WH, Swartzwelder HS. Prenatal choline exposure alters hippocampal responsiveness to cholinergic stimulation in adulthood. Brain Research. Developmental Brain Research. 123: 25-32. PMID 11020547 DOI: 10.1016/S0165-3806(00)00075-4  0.64
2000 Malik MA, Greenwood CE, Blusztajn JK, Berse B. Cholinergic differentiation triggered by blocking cell proliferation and treatment with all-trans-retinoic acid. Brain Research. 874: 178-85. PMID 10960602 DOI: 10.1016/S0006-8993(00)02575-0  0.64
2000 López-Coviella I, Berse B, Krauss R, Thies RS, Blusztajn JK. Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9. Science (New York, N.Y.). 289: 313-6. PMID 10894782 DOI: 10.1126/science.289.5477.313  0.64
2000 Blusztajn JK, Berse B. The cholinergic neuronal phenotype in Alzheimer's disease. Metabolic Brain Disease. 15: 45-64. PMID 10885540 DOI: 10.1023/A:1011161718572  0.64
2000 Fiucci G, Czarny M, Lavie Y, Zhao D, Berse B, Blusztajn JK, Liscovitch M. Changes in phospholipase D isoform activity and expression in multidrug-resistant human cancer cells. International Journal of Cancer. Journal International Du Cancer. 85: 882-8. PMID 10709112 DOI: 10.1002/(SICI)1097-0215(20000315)85:6<882::AID-IJC24>3.0.CO;2-E  0.64
2000 Koziak K, Kaczmarek E, Kittel A, Sévigny J, Blusztajn JK, Schulte Am Esch J, Imai M, Guckelberger O, Goepfert C, Qawi I, Robson SC. Palmitoylation targets CD39/endothelial ATP diphosphohydrolase to caveolae. The Journal of Biological Chemistry. 275: 2057-62. PMID 10636909 DOI: 10.1074/jbc.275.3.2057  0.64
1999 Schreiber BM, Veverbrants M, Fine RE, Blusztajn JK, Salmona M, Patel A, Sipe JD. Apolipoprotein serum amyloid A down-regulates smooth-muscle cell lipid biosynthesis. The Biochemical Journal. 344: 7-13. PMID 10548527 DOI: 10.1042/0264-6021:3440007  0.64
1999 Berse B, Lopez-Coviella I, Blusztajn JK. Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor. The Biochemical Journal. 342: 301-8. PMID 10455015 DOI: 10.1042/0264-6021:3420301  0.64
1999 Cermak JM, Blusztajn JK, Meck WH, Williams CL, Fitzgerald CM, Rosene DL, Loy R. Prenatal availability of choline alters the development of acetylcholinesterase in the rat hippocampus. Developmental Neuroscience. 21: 94-104. PMID 10449981 DOI: 10.1159/000017371  0.64
1999 Szutowicz A, Jankowska A, Blusztajn JK, Tomaszewicz M. Acetylcholine and acetyl-CoA metabolism in differentiating SN56 septal cell line. Journal of Neuroscience Research. 57: 131-6. PMID 10397643 DOI: 10.1002/(SICI)1097-4547(19990701)57:1<131::AID-JNR14>3.0.CO;2-M  0.64
1998 Blusztajn JK, Cermak JM, Holler T, Jackson DA. Imprinting of hippocampal metabolism of choline by its availability during gestation: implications for cholinergic neurotransmission. Journal of Physiology, Paris. 92: 199-203. PMID 9789808 DOI: 10.1016/S0928-4257(98)80010-7  0.64
1998 Zhao D, Berse B, Holler T, Cermak JM, Blusztajn JK. Developmental changes in phospholipase D activity and mRNA levels in rat brain. Brain Research. Developmental Brain Research. 109: 121-7. PMID 9729325 DOI: 10.1016/S0165-3806(98)00071-6  0.64
1998 Blusztajn JK. Choline, a vital amine. Science (New York, N.Y.). 281: 794-5. PMID 9714685 DOI: 10.1126/science.281.5378.794  0.64
1998 Johnson PI, Blusztajn JK. Sexually dimorphic activation of liver and brain phosphatidylethanolamine N-methyltransferase by dietary choline deficiency. Neurochemical Research. 23: 583-7. PMID 9566595 DOI: 10.1023/A:1022470301550  0.64
1998 Cermak JM, Holler T, Jackson DA, Blusztajn JK. Prenatal availability of choline modifies development of the hippocampal cholinergic system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 349-57. PMID 9506479  0.64
1998 Schreiber BM, Veverbrants M, Fine RE, Blusztajn JK, Patel A, Sipe JD. Interleukin-1α (IL-1α) and Apolipoprotein Serum Amyloid A (ApoSAA) down regulate smooth muscle cell lipid biosynthesis Faseb Journal. 12: A705.  0.64
1997 Jankowska A, Blusztajn JK, Szutowicz A. Activities of enzymes of acetyl-CoA and acetylcholine metabolism in SN56 hybrid cholinergic cell line differentiated by dibutyryl cyclic AMP and all-trans retinoic acid. Folia Neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences. 35: 247-9. PMID 9833404  0.64
1997 Pedersen WA, Blusztajn JK. Characterization of the acetylcholine-reducing effect of the amyloid-beta peptide in mouse SN56 cells. Neuroscience Letters. 239: 77-80. PMID 9469660 DOI: 10.1016/S0304-3940(97)00913-0  0.64
1997 Li H, Leeman SE, Slack BE, Hauser G, Saltsman WS, Krause JE, Blusztajn JK, Boyd ND. A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. Proceedings of the National Academy of Sciences of the United States of America. 94: 9475-80. PMID 9256507 DOI: 10.1073/pnas.94.17.9475  0.64
1997 Berse B, Blusztajn JK. Modulation of cholinergic locus expression by glucocorticoids and retinoic acid is cell-type specific. Febs Letters. 410: 175-9. PMID 9237624 DOI: 10.1016/S0014-5793(97)00568-1  0.64
1997 Veronesi B, Ehrich M, Blusztajn JK, Oortgiesen M, Durham H. Cell culture models of interspecies selectivity to organophosphorous insecticides. Neurotoxicology. 18: 283-97. PMID 9216006  0.64
1997 Ross BM, Moszczynska A, Blusztajn JK, Sherwin A, Lozano A, Kish SJ. Phospholipid biosynthetic enzymes in human brain. Lipids. 32: 351-8. PMID 9113621 DOI: 10.1007/s11745-997-0044-x  0.64
1996 Lemere CA, Blusztajn JK, Yamaguchi H, Wisniewski T, Saido TC, Selkoe DJ. Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation. Neurobiology of Disease. 3: 16-32. PMID 9173910 DOI: 10.1006/nbdi.1996.0003  0.64
1996 Holler T, Cermak JM, Blusztajn JK. Dietary choline supplementation in pregnant rats increases hippocampal phospholipase D activity of the offspring. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 1653-9. PMID 9002559  0.64
1996 Holler T, Berse B, Cermak JM, Diebler MF, Blusztajn JK. Differences in the developmental expression of the vesicular acetylcholine transporter and choline acetyltransferase in the rat brain. Neuroscience Letters. 212: 107-10. PMID 8832650 DOI: 10.1016/0304-3940(96)12808-1  0.64
1996 Pedersen WA, Kloczewiak MA, Blusztajn JK. Amyloid beta-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain. Proceedings of the National Academy of Sciences of the United States of America. 93: 8068-71. PMID 8755604 DOI: 10.1073/pnas.93.15.8068  0.64
1995 Pedersen WA, Berse B, Schüler U, Wainer BH, Blusztajn JK. All-trans- and 9-cis-retinoic acid enhance the cholinergic properties of a murine septal cell line: evidence that the effects are mediated by activation of retinoic acid receptor-alpha. Journal of Neurochemistry. 65: 50-8. PMID 7790895  0.64
1995 Berse B, Blusztajn JK. Coordinated up-regulation of choline acetyltransferase and vesicular acetylcholine transporter gene expression by the retinoic acid receptor alpha, cAMP, and leukemia inhibitory factor/ciliary neurotrophic factor signaling pathways in a murine septal cell line. The Journal of Biological Chemistry. 270: 22101-4. PMID 7673184 DOI: 10.1074/jbc.270.38.22101  0.64
1995 Brotschi EA, Hilbinger CL, Kahl EA, Vaules WA, Midis NA, Blusztajn JK, Zeisel SH. Radioactive choline metabolism in guinea pig gallbladder. Is there measurable acetylcholine release? Digestive Diseases and Sciences. 40: 1982-9. PMID 7555453 DOI: 10.1007/BF02208667  0.64
1995 Blusztajn JK, Davis RO. Use of differentiated cholinergic and second messenger endpoints to evaluate cholinesterase inhibitors. Clinical and Experimental Pharmacology & Physiology. 22: 368-9. PMID 7554433  0.64
1995 Gruber JR, Desai S, Blusztajn JK, Niles RM. Retinoic acid specifically increases nuclear PKC alpha and stimulates AP-1 transcriptional activity in B16 mouse melanoma cells. Experimental Cell Research. 221: 377-84. PMID 7493637 DOI: 10.1006/excr.1995.1388  0.64
1994 Lavie Y, Blusztajn JK, Liscovitch M. Formation of endogenous free sphingoid bases in cells induced by changing medium conditions. Biochimica Et Biophysica Acta. 1220: 323-8. PMID 8305506 DOI: 10.1016/0167-4889(94)90156-2  0.64
1994 Hudson PL, Pedersen WA, Saltsman WS, Liscovitch M, MacLaughlin DT, Donahoe PK, Blusztajn JK. Modulation by sphingolipids of calcium signals evoked by epidermal growth factor. The Journal of Biological Chemistry. 269: 21885-90. PMID 8063833  0.64
1994 Zeisel SH, Blusztajn JK. Choline and human nutrition. Annual Review of Nutrition. 14: 269-96. PMID 7946521 DOI: 10.1146/annurev.nu.14.070194.001413  0.64
1994 Blusztajn JK. Alzheimer's disease: prevention, models, and diagnostic tools. Neurobiology of Aging. 15: S37-9. PMID 7700457 DOI: 10.1016/0197-4580(94)90165-1  0.64
1993 da Costa KA, Cochary EF, Blusztajn JK, Garner SC, Zeisel SH. Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline-deficient rats. The Journal of Biological Chemistry. 268: 2100-5. PMID 8420980  0.64
1993 Nitsch RM, Blusztajn JK, Doyle FM, Robitaille Y, Wurtman RJ, Growdon JH, Kish SJ. Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy. Neuroscience Letters. 161: 191-4. PMID 8272265 DOI: 10.1016/0304-3940(93)90291-R  0.64
1993 Lee HC, Fellenz-Maloney MP, Liscovitch M, Blusztajn JK. Phospholipase D-catalyzed hydrolysis of phosphatidylcholine provides the choline precursor for acetylcholine synthesis in a human neuronal cell line. Proceedings of the National Academy of Sciences of the United States of America. 90: 10086-90. PMID 8234260 DOI: 10.1073/pnas.90.21.10086  0.64
1992 Cashman NR, Durham HD, Blusztajn JK, Oda K, Tabira T, Shaw IT, Dahrouge S, Antel JP. Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 194: 209-21. PMID 1467557 DOI: 10.1002/aja.1001940306  0.64
1992 Blusztajn JK, Venturini A, Jackson DA, Lee HJ, Wainer BH. Acetylcholine synthesis and release is enhanced by dibutyryl cyclic AMP in a neuronal cell line derived from mouse septum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 793-9. PMID 1312135  0.64
1992 Nitsch RM, Blusztajn JK, Pittas AG, Slack BE, Growdon JH, Wurtman RJ. Evidence for a membrane defect in Alzheimer disease brain. Proceedings of the National Academy of Sciences of the United States of America. 89: 1671-5. PMID 1311847  0.64
1991 Nitsch R, Pittas A, Blusztajn JK, Slack BE, Growdon JH, Wurtman RJ. Alterations of phospholipid metabolites in postmortem brain from patients with Alzheimer's disease. Annals of the New York Academy of Sciences. 640: 110-3. PMID 1663712  0.64
1990 Wurtman RJ, Blusztajn JK, Ulus IH, Coviella IL, Buyukuysal RL, Growdon JH, Slack BE. Choline metabolism in cholinergic neurons: implications for the pathogenesis of neurodegenerative diseases. Advances in Neurology. 51: 117-25. PMID 2403709  0.64
1990 Blusztajn JK, Lopez Gonzalez-Coviella I, Logue M, Growdon JH, Wurtman RJ. Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients. Brain Research. 536: 240-4. PMID 2150771 DOI: 10.1016/0006-8993(90)90030-F  0.64
1989 Blusztajn JK, Zeisel SH. 1,2-sn-diacylglycerol accumulates in choline-deficient liver. A possible mechanism of hepatic carcinogenesis via alteration in protein kinase C activity? Febs Letters. 243: 267-70. PMID 2917651 DOI: 10.1016/0014-5793(89)80142-5  0.64
1989 Slack BE, Liscovitch M, Blusztajn JK, Wurtman RJ. Uptake of exogenous phosphatidylserine by human neuroblastoma cells stimulates the incorporation of [methyl-14C]choline into phosphatidylcholine. Journal of Neurochemistry. 53: 472-81. PMID 2746233  0.64
1989 Ulus IH, Wurtman RJ, Mauron C, Blusztajn JK. Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum. Brain Research. 484: 217-27. PMID 2713682 DOI: 10.1016/0006-8993(89)90364-8  0.64
1989 Conlay LA, Wurtman RJ, Lopez G-Coviella I, Blusztajn JK, Vacanti CA, Logue M, During M, Caballero B, Maher TJ, Evoniuk G. Effects of running the Boston marathon on plasma concentrations of large neutral amino acids. Journal of Neural Transmission. 76: 65-71. PMID 2708978 DOI: 10.1007/BF01244992  0.64
1989 Richardson UI, Liscovitch M, Blusztajn JK. Acetylcholine synthesis and secretion by LA-N-2 human neuroblastoma cells. Brain Research. 476: 323-31. PMID 2702472 DOI: 10.1016/0006-8993(89)91253-5  0.64
1989 Wurtman RJ, Ulus IH, Blusztajn JK, Lopez-Coviella I, Agut J, Ortiz JA, Logue M, Mauron C, Growdon JH. Choline levels, the regulation of acetylcholine and phosphatidylcholine synthesis, and Alzheimer's disease Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 1: 15. DOI: 10.1007/BF02312196  0.64
1988 Yang EK, Blusztajn JK, Pomfret EA, Zeisel SH. Rat and human mammary tissue can synthesize choline moiety via the methylation of phosphatidylethanolamine. The Biochemical Journal. 256: 821-8. PMID 3223955  0.64
1987 Hilibrand AS, Ingrid Richardson U, Blusztajn JK, Wurtman RJ. NG108-15 hybrid cells take up but do not synthesize serotonin. Neurochemistry International. 10: 185-9. PMID 20501069 DOI: 10.1016/0197-0186(87)90126-4  0.64
1987 Liscovitch M, Slack B, Blusztajn JK, Wurtman RJ. Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells. The Journal of Biological Chemistry. 262: 17487-91. PMID 3693364  0.64
1987 Liscovitch M, Blusztajn JK, Freese A, Wurtman RJ. Stimulation of choline release from NG108-15 cells by 12-O-tetradecanoylphorbol 13-acetate. The Biochemical Journal. 241: 81-6. PMID 3566713  0.64
1987 Blusztajn JK, Liscovitch M, Richardson UI. Synthesis of acetylcholine from choline derived from phosphatidylcholine in a human neuronal cell line. Proceedings of the National Academy of Sciences of the United States of America. 84: 5474-7. PMID 3474663  0.64
1987 Blusztajn JK, Liscovitch M, Mauron C, Richardson UI, Wurtman RJ. Phosphatidylcholine as a precursor of choline for acetylcholine synthesis. Journal of Neural Transmission. Supplementum. 24: 247-59. PMID 3316498  0.64
1986 Liscovitch M, Freese A, Blusztajn JK, Wurtman RJ. Phosphatidylcholine biosynthesis in the neuroblastoma-glioma hybrid cell line NG108-15: stimulation by phorbol esters. Journal of Neurochemistry. 47: 1936-41. PMID 3772385  0.64
1986 Blusztajn JK, Holbrook PG, Lakher M, Liscovitch M, Maire JC, Mauron C, Richardson UI, Tacconi M, Wurtman RJ. "Autocannibalism" of membrane choline-phospholipids: physiology and pathology. Psychopharmacology Bulletin. 22: 781-6. PMID 3025910  0.64
1985 Wurtman RJ, Blusztajn JK, Maire JC. "Autocannibalism" of choline-containing membrane phospholipids in the pathogenesis of Alzheimer's disease-A hypothesis. Neurochemistry International. 7: 369-72. PMID 20492936 DOI: 10.1016/0197-0186(85)90127-5  0.64
1985 Blusztajn JK, Zeisel SH, Wurtman RJ. Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain. The Biochemical Journal. 232: 505-11. PMID 4091805  0.64
1985 Liscovitch M, Freese A, Blusztajn JK, Wurtman RJ. High-performance liquid chromatography of water-soluble choline metabolites. Analytical Biochemistry. 151: 182-7. PMID 4091278 DOI: 10.1016/0003-2697(85)90069-7  0.64
1983 Blusztajn JK, Wurtman RJ. Choline and cholinergic neurons Science. 221: 614-620. PMID 6867732  0.64
1983 Zeisel SH, Wishnok JS, Blusztajn JK. Formation of methylamines from ingested choline and lecithin. The Journal of Pharmacology and Experimental Therapeutics. 225: 320-4. PMID 6842395  0.64
1983 Leprohon CE, Blusztajn JK, Wurtman RJ. Dopamine stimulation of phosphatidylcholine (lecithin) biosynthesis in rat brain neurons Proceedings of the National Academy of Sciences of the United States of America. 80: 2063-2066. PMID 6572961  0.64
1981 Blusztajn JK, Wurtman RJ. Choline biosynthesis by a preparation enriched in synaptosomes from rat brain Nature. 290: 417-418. PMID 7219528 DOI: 10.1038/290417a0  0.64
1979 Blusztajn JK, Zeisel SH, Wurtman RJ. Synthesis of lecithin (phosphatidylcholine) from phosphatidylethanolamine in bovine brain. Brain Research. 179: 319-27. PMID 509240 DOI: 10.1016/0006-8993(79)90447-5  0.64
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