| Year |
Citation |
Score |
| 2024 |
Loan Nguyen TM, Guilloux JP, Defaix C, Mendez-David I, Etting I, Alvarez JC, McGowan JC, Highland JN, Zanos P, Lovett J, Moaddel R, Corruble E, David DJ, Gould TD, Denny CA, et al. Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions. Neuropharmacology. 110065. PMID 39004413 DOI: 10.1016/j.neuropharm.2024.110065 |
0.758 |
|
| 2022 |
Georgiou P, Zanos P, Mou TM, An X, Gerhard DM, Dryanovski DI, Potter LE, Highland JN, Jenne CE, Stewart BW, Pultorak KJ, Yuan P, Powels CF, Lovett J, Pereira EFR, et al. Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor. Nature Neuroscience. PMID 36042309 DOI: 10.1038/s41593-022-01146-x |
0.697 |
|
| 2022 |
Highland JN, Morris PJ, Konrath KM, Riggs LM, Hagen NR, Zanos P, Powels CF, Moaddel R, Thomas CJ, Wang AQ, Gould TD. Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (26)- and (5)-Methyl-(26)-hydroxynorketamines. Acs Chemical Neuroscience. 13: 510-523. PMID 35113535 DOI: 10.1021/acschemneuro.1c00761 |
0.759 |
|
| 2021 |
Highland JN, Farmer CA, Zanos P, Lovett J, Zarate CA, Moaddel R, Gould TD. Sex-dependent metabolism of ketamine and ()-hydroxynorketamine in mice and humans. Journal of Psychopharmacology (Oxford, England). 2698811211064922. PMID 34971525 DOI: 10.1177/02698811211064922 |
0.716 |
|
| 2021 |
Highland JN, Zanos P, Riggs LM, Georgiou P, Clark SM, Morris PJ, Moaddel R, Thomas CJ, Zarate CA, Pereira EFR, Gould TD. Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications. Pharmacological Reviews. 73: 763-791. PMID 33674359 DOI: 10.1124/pharmrev.120.000149 |
0.744 |
|
| 2020 |
Wang AQ, Konrath KM, Highland JN, Riggs LM, Morris PJ, Thomas C, Gould TD, Xu X. P199 - HILIC UPLC-MS/MS methods for the assessment of hydroxynorketamines pharmacokinetics in mouse plasma and brain Drug Metabolism and Pharmacokinetics. 35. DOI: 10.1016/J.Dmpk.2020.04.200 |
0.721 |
|
| 2019 |
Zanos P, Highland JN, Liu X, Troppoli TA, Georgiou P, Lovett J, Morris PJ, Stewart BW, Thomas CJ, Thompson SM, Moaddel R, Gould TD. (R)-ketamine exerts antidepressant actions partly via conversion to (2R,6R)-hydroxynorketamine, while causing adverse effects at sub-anesthetic doses. British Journal of Pharmacology. PMID 30941749 DOI: 10.1111/Bph.14683 |
0.742 |
|
| 2019 |
Highland JN, Zanos P, Georgiou P, Gould TD. Group II metabotropic glutamate receptor blockade promotes stress resilience in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30939596 DOI: 10.1038/S41386-019-0380-1 |
0.768 |
|
| 2019 |
Zanos P, Highland JN, Stewart BW, Georgiou P, Jenne CE, Lovett J, Morris PJ, Thomas CJ, Moaddel R, Zarate CA, Gould TD. ()-hydroxynorketamine exerts mGlu receptor-dependent antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30867285 DOI: 10.1073/Pnas.1819540116 |
0.783 |
|
| 2018 |
Highland JN, Morris PJ, Zanos P, Lovett J, Ghosh S, Wang AQ, Zarate CA, Thomas CJ, Moaddel R, Gould TD. Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine. Journal of Psychopharmacology (Oxford, England). 269881118812095. PMID 30488740 DOI: 10.1177/0269881118812095 |
0.737 |
|
| 2018 |
Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA, Gould TD. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. Pharmacological Reviews. 70: 621-660. PMID 29945898 DOI: 10.1124/Pr.117.015198 |
0.732 |
|
| 2018 |
Georgiou P, Zanos P, Jenne C, Highland J, Gerhard D, Duman R, Gould T. F102. Human Experimenter Sex Modulates Mouse Behavioral Responses to Stress and to the Antidepressant Ketamine Biological Psychiatry. 83: S277. DOI: 10.1016/J.Biopsych.2018.02.715 |
0.752 |
|
| 2018 |
Highland J, Zanos P, Georgiou P, Gould T. T89. Group II Metabotropic Glutamate Receptor Blockade Promotes Stress Resilience Biological Psychiatry. 83: S163. DOI: 10.1016/J.Biopsych.2018.02.425 |
0.737 |
|
| 2017 |
Zanos P, Nelson ME, Highland JN, Krimmel SR, Georgiou P, Gould TD, Thompson SM. A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice. Eneuro. 4. PMID 28275719 DOI: 10.1523/ENEURO.0285-16.2017 |
0.773 |
|
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