| Year |
Citation |
Score |
| 2024 |
Raja SM, Guptill JT, Mack M, Peterson M, Byard S, Twieg R, Jordan L, Rich N, Castledine R, Bourne S, Wilmshurst M, Oxendine S, Avula SGC, Zuleta H, Quigley P, ... ... Zanos P, et al. A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2R,6R)-Hydroxynorketamine in Healthy Volunteers. Clinical Pharmacology and Therapeutics. PMID 39054770 DOI: 10.1002/cpt.3391 |
0.557 |
|
| 2024 |
Loan Nguyen TM, Guilloux JP, Defaix C, Mendez-David I, Etting I, Alvarez JC, McGowan JC, Highland JN, Zanos P, Lovett J, Moaddel R, Corruble E, David DJ, Gould TD, Denny CA, et al. Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions. Neuropharmacology. 110065. PMID 39004413 DOI: 10.1016/j.neuropharm.2024.110065 |
0.816 |
|
| 2024 |
Onisiforou A, Zanos P, Georgiou P. Molecular signatures of premature aging in Major Depression and Substance Use Disorders. Scientific Data. 11: 698. PMID 38926475 DOI: 10.1038/s41597-024-03538-z |
0.774 |
|
| 2024 |
Onisiforou A, Christodoulou CC, Zamba-Papanicolaou E, Zanos P, Georgiou P. Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer's disease. Frontiers in Endocrinology. 15: 1345498. PMID 38689734 DOI: 10.3389/fendo.2024.1345498 |
0.759 |
|
| 2024 |
Bendis PC, Zimmerman S, Onisiforou A, Zanos P, Georgiou P. The impact of estradiol on serotonin, glutamate, and dopamine systems. Frontiers in Neuroscience. 18: 1348551. PMID 38586193 DOI: 10.3389/fnins.2024.1348551 |
0.801 |
|
| 2023 |
Christodoulou CC, Onisiforou A, Zanos P, Papanicolaou EZ. Unraveling the transcriptomic signatures of Parkinson's disease and major depression using single-cell and bulk data. Frontiers in Aging Neuroscience. 15: 1273855. PMID 38020762 DOI: 10.3389/fnagi.2023.1273855 |
0.759 |
|
| 2023 |
Onisiforou A, Georgiou P, Zanos P. Role of group II metabotropic glutamate receptors in ketamine's antidepressant actions. Pharmacology, Biochemistry, and Behavior. 223: 173531. PMID 36841543 DOI: 10.1016/j.pbb.2023.173531 |
0.809 |
|
| 2023 |
Zanos P, Brown KA, Georgiou P, Yuan P, Zarate CA, Thompson SM, Gould TD. NMDA RECEPTOR ACTIVATION-DEPENDENT ANTIDEPRESSANT-RELEVANT BEHAVIORAL AND SYNAPTIC ACTIONS OF KETAMINE. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36596696 DOI: 10.1523/JNEUROSCI.1316-22.2022 |
0.815 |
|
| 2022 |
Brown KA, Zanos P, Powels CF, Fix CJ, Michaelides M, Pereira EFR, Moaddel R, Gould TD. Ketamine preservative benzethonium chloride potentiates hippocampal synaptic transmission and binds neurotransmitter receptors and transporters. Neuropharmacology. 225: 109403. PMID 36565852 DOI: 10.1016/j.neuropharm.2022.109403 |
0.635 |
|
| 2022 |
Georgiou P, Zanos P, Mou TM, An X, Gerhard DM, Dryanovski DI, Potter LE, Highland JN, Jenne CE, Stewart BW, Pultorak KJ, Yuan P, Powels CF, Lovett J, Pereira EFR, et al. Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor. Nature Neuroscience. PMID 36042309 DOI: 10.1038/s41593-022-01146-x |
0.775 |
|
| 2022 |
Bonaventura J, Gomez JL, Carlton ML, Lam S, Sanchez-Soto M, Morris PJ, Moaddel R, Kang HJ, Zanos P, Gould TD, Thomas CJ, Sibley DR, Zarate CA, Michaelides M. Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search. Molecular Psychiatry. PMID 35768639 DOI: 10.1038/s41380-022-01673-w |
0.597 |
|
| 2022 |
Moaddel R, Zanos P, Farmer CA, Kadriu B, Morris PJ, Lovett J, Acevedo-Diaz EE, Cavanaugh GW, Yuan P, Yavi M, Thomas CJ, Park LT, Ferrucci L, Gould TD, Zarate CA. Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration. Translational Psychiatry. 12: 179. PMID 35501309 DOI: 10.1038/s41398-022-01941-x |
0.63 |
|
| 2022 |
Highland JN, Morris PJ, Konrath KM, Riggs LM, Hagen NR, Zanos P, Powels CF, Moaddel R, Thomas CJ, Wang AQ, Gould TD. Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (26)- and (5)-Methyl-(26)-hydroxynorketamines. Acs Chemical Neuroscience. 13: 510-523. PMID 35113535 DOI: 10.1021/acschemneuro.1c00761 |
0.794 |
|
| 2021 |
Troppoli TA, Zanos P, Georgiou P, Gould TD, Rudolph U, Thompson SM. Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. Biological Psychiatry. PMID 35120711 DOI: 10.1016/j.biopsych.2021.11.024 |
0.79 |
|
| 2021 |
Highland JN, Farmer CA, Zanos P, Lovett J, Zarate CA, Moaddel R, Gould TD. Sex-dependent metabolism of ketamine and ()-hydroxynorketamine in mice and humans. Journal of Psychopharmacology (Oxford, England). 2698811211064922. PMID 34971525 DOI: 10.1177/02698811211064922 |
0.788 |
|
| 2021 |
Osman A, Zuffa S, Walton G, Fagbodun E, Zanos P, Georgiou P, Kitchen I, Swann J, Bailey A. Post-weaning A1/A2 β-casein milk intake modulates depressive-like behavior, brain μ-opioid receptors, and the metabolome of rats. Iscience. 24: 103048. PMID 34585111 DOI: 10.1016/j.isci.2021.103048 |
0.78 |
|
| 2021 |
Morris PJ, Burke RD, Sharma AK, Lynch DC, Lemke-Boutcher LE, Mathew S, Elayan I, Rao DB, Gould TD, Zarate CA, Zanos P, Moaddel R, Thomas CJ. A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801. Neurotoxicology and Teratology. 106993. PMID 33945878 DOI: 10.1016/j.ntt.2021.106993 |
0.617 |
|
| 2021 |
Highland JN, Zanos P, Riggs LM, Georgiou P, Clark SM, Morris PJ, Moaddel R, Thomas CJ, Zarate CA, Pereira EFR, Gould TD. Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications. Pharmacological Reviews. 73: 763-791. PMID 33674359 DOI: 10.1124/pharmrev.120.000149 |
0.794 |
|
| 2020 |
Elmer GI, Tapocik JD, Mayo CL, Zanos P, Gould TD. Ketamine metabolite (2R,6R)-hydroxynorketamine reverses behavioral despair produced by adolescent trauma. Pharmacology, Biochemistry, and Behavior. 172973. PMID 32569786 DOI: 10.1016/J.Pbb.2020.172973 |
0.655 |
|
| 2020 |
Park LT, Kadriu B, Gould TD, Zanos P, Greenstein D, Evans JW, Yuan P, Farmer CA, Oppenheimer M, George JM, Adeojo LW, Snodgrass HR, Smith MA, Henter ID, Machado-Vieira R, et al. A Randomized Trial of the N-methyl-d-aspartate Receptor Glycine Site Antagonist Prodrug 4-chlorokynurenine in Treatment-Resistant Depression. The International Journal of Neuropsychopharmacology. PMID 32236521 DOI: 10.1093/Ijnp/Pyaa025 |
0.66 |
|
| 2020 |
Zhang Y, Zanos P, Jackson IL, Zhang X, Zhu X, Gould T, Vujaskovic Z. Psychological stress enhances tumor growth and diminishes radiation response in preclinical model of lung cancer. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 146: 126-135. PMID 32146258 DOI: 10.1016/J.Radonc.2020.02.004 |
0.579 |
|
| 2020 |
Potter LE, Zanos P, Gould TD. Antidepressant Effects and Mechanisms of Group II mGlu Receptor-Specific Negative Allosteric Modulators. Neuron. 105: 1-3. PMID 31951525 DOI: 10.1016/J.Neuron.2019.12.011 |
0.799 |
|
| 2019 |
Krimmel SR, Zanos P, Georgiou P, Colloca L, Gould TD. Classical conditioning of antidepressant placebo effects in mice. Psychopharmacology. PMID 31422429 DOI: 10.1007/S00213-019-05347-4 |
0.795 |
|
| 2019 |
Riggs LM, Aracava Y, Zanos P, Fischell J, Albuquerque EX, Pereira EFR, Thompson SM, Gould TD. (2R,6R)-hydroxynorketamine acts through a synapse-specific presynaptic mechanism to rapidly potentiate hippocampal glutamatergic transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31216563 DOI: 10.1038/S41386-019-0443-3 |
0.791 |
|
| 2019 |
Zanos P, Highland JN, Liu X, Troppoli TA, Georgiou P, Lovett J, Morris PJ, Stewart BW, Thomas CJ, Thompson SM, Moaddel R, Gould TD. (R)-ketamine exerts antidepressant actions partly via conversion to (2R,6R)-hydroxynorketamine, while causing adverse effects at sub-anesthetic doses. British Journal of Pharmacology. PMID 30941749 DOI: 10.1111/Bph.14683 |
0.775 |
|
| 2019 |
Highland JN, Zanos P, Georgiou P, Gould TD. Group II metabotropic glutamate receptor blockade promotes stress resilience in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30939596 DOI: 10.1038/S41386-019-0380-1 |
0.798 |
|
| 2019 |
Zanos P, Highland JN, Stewart BW, Georgiou P, Jenne CE, Lovett J, Morris PJ, Thomas CJ, Moaddel R, Zarate CA, Gould TD. ()-hydroxynorketamine exerts mGlu receptor-dependent antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30867285 DOI: 10.1073/Pnas.1819540116 |
0.818 |
|
| 2019 |
Georgiou P, Zanos P, Jenne CE, Gould TD. Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation. Frontiers in Psychiatry. 10: 81. PMID 30863326 DOI: 10.3389/Fpsyt.2019.00081 |
0.804 |
|
| 2019 |
Rao X, Asico LD, Zanos P, Mahabeleshwar GH, Singh Gangwar R, Xia C, Duan L, Cisse YM, Rengasamy P, Jose PA, Gould TD, Nelson R, Biswal S, Chen LC, Zhong J, et al. Alpha2B-Adrenergic Receptor Overexpression in the Brain Potentiate Air Pollution-induced Behavior and Blood Pressure Changes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30812033 DOI: 10.1093/Toxsci/Kfz025 |
0.624 |
|
| 2019 |
Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA, et al. Antidepressant-relevant concentrations of the ketamine metabolite (2,6)-hydroxynorketamine do not block NMDA receptor function. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796190 DOI: 10.1073/Pnas.1816071116 |
0.724 |
|
| 2018 |
Highland JN, Morris PJ, Zanos P, Lovett J, Ghosh S, Wang AQ, Zarate CA, Thomas CJ, Moaddel R, Gould TD. Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine. Journal of Psychopharmacology (Oxford, England). 269881118812095. PMID 30488740 DOI: 10.1177/0269881118812095 |
0.798 |
|
| 2018 |
Zanos P, Keyworth H, Georgiou P, Kitchen I, Zimmer A, Bailey A. Chronic nicotine administration restores brain region specific up-regulation of oxytocin receptor binding levels in a G72 mouse model of schizophrenia. The European Journal of Neuroscience. PMID 30218618 DOI: 10.1111/Ejn.14155 |
0.79 |
|
| 2018 |
Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA, Gould TD. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. Pharmacological Reviews. 70: 621-660. PMID 29945898 DOI: 10.1124/Pr.117.015198 |
0.794 |
|
| 2018 |
Rae M, Zanos P, Georgiou P, Chivers P, Bailey A, Camarini R. Environmental enrichment enhances conditioned place preference to ethanol via an oxytocinergic-dependent mechanism in male mice. Neuropharmacology. PMID 29908241 DOI: 10.1016/J.Neuropharm.2018.06.013 |
0.782 |
|
| 2018 |
Brown PL, Zanos P, Wang L, Elmer GI, Gould TD, Shepard PD. Isoflurane but not Halothane Prevents and Reverses Helpless Behavior: A Role for EEG Burst Suppression? The International Journal of Neuropsychopharmacology. PMID 29554264 DOI: 10.1093/Ijnp/Pyy029 |
0.634 |
|
| 2018 |
Zanos P, Gould TD. Mechanisms of ketamine action as an antidepressant. Molecular Psychiatry. PMID 29532791 DOI: 10.1038/Mp.2017.255 |
0.682 |
|
| 2018 |
Zanos P, Thompson SM, Duman RS, Zarate CA, Gould TD. Convergent Mechanisms Underlying Rapid Antidepressant Action. Cns Drugs. PMID 29516301 DOI: 10.1007/S40263-018-0492-X |
0.751 |
|
| 2018 |
García-Carmona JA, Georgiou P, Zanos P, Bailey A, Laorden ML. Methamphetamine withdrawal induces activation of CRF neurons in the brain stress system in parallel with an increased activity of cardiac sympathetic pathways. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 29383398 DOI: 10.1007/S00210-018-1470-Z |
0.784 |
|
| 2018 |
Zanos P, Gould TD. Intracellular Signaling Pathways Involved in (S)- and (R)-Ketamine Antidepressant Actions. Biological Psychiatry. 83: 2-4. PMID 29173705 DOI: 10.1016/J.Biopsych.2017.10.026 |
0.625 |
|
| 2018 |
Georgiou P, Zanos P, Jenne C, Highland J, Gerhard D, Duman R, Gould T. F102. Human Experimenter Sex Modulates Mouse Behavioral Responses to Stress and to the Antidepressant Ketamine Biological Psychiatry. 83: S277. DOI: 10.1016/J.Biopsych.2018.02.715 |
0.768 |
|
| 2018 |
Highland J, Zanos P, Georgiou P, Gould T. T89. Group II Metabotropic Glutamate Receptor Blockade Promotes Stress Resilience Biological Psychiatry. 83: S163. DOI: 10.1016/J.Biopsych.2018.02.425 |
0.771 |
|
| 2017 |
Keyworth H, Georgiou P, Zanos P, Rueda AV, Chen Y, Kitchen I, Camarini R, Cropley M, Bailey A. Wheel running during chronic nicotine exposure is protective against mecamylamine-precipitated withdrawal and up-regulates hippocampal α7 nACh receptors in mice. British Journal of Pharmacology. PMID 29266170 DOI: 10.1111/Bph.14068 |
0.792 |
|
| 2017 |
Morris PJ, Moaddel R, Zanos P, Moore CE, Gould TD, Zarate CA, Thomas CJ. Correction to "Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites". Organic Letters. PMID 28933164 DOI: 10.1021/Acs.Orglett.7B02839 |
0.62 |
|
| 2017 |
Morris PJ, Moaddel R, Zanos P, Moore CE, Gould T, Zarate CA, Thomas CJ. Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites. Organic Letters. PMID 28829612 DOI: 10.1021/Acs.Orglett.7B02177 |
0.644 |
|
| 2017 |
Georgiou P, Zanos P, Bhat S, Tracy JK, Merchenthaler IJ, McCarthy MM, Gould TD. Dopamine and Stress System Modulation of Sex Differences in Decision Making. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28741626 DOI: 10.1038/Npp.2017.161 |
0.771 |
|
| 2017 |
Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KSS, Fang Y, Huang XP, Mayo CL, Albuquerque EX, et al. Zanos et al. reply. Nature. 546: E4-E5. PMID 28640272 DOI: 10.1038/Nature22085 |
0.739 |
|
| 2017 |
Gould TD, Georgiou P, Brenner LA, Brundin L, Can A, Courtet P, Donaldson ZR, Dwivedi Y, Guillaume S, Gottesman II, Kanekar S, Lowry CA, Renshaw PF, Rujescu D, Smith EG, ... ... Zanos P, et al. Animal models to improve our understanding and treatment of suicidal behavior. Translational Psychiatry. 7: e1092. PMID 28398339 DOI: 10.1038/Tp.2017.50 |
0.764 |
|
| 2017 |
Zanos P, Georgiou P, Weber C, Robinson F, Kouimtsidis C, Niforooshan R, Bailey A. Oxytocin and opioid addiction revisited: Old drug, new applications. British Journal of Pharmacology. PMID 28378414 DOI: 10.1111/Bph.13757 |
0.792 |
|
| 2017 |
Zanos P, Nelson ME, Highland JN, Krimmel SR, Georgiou P, Gould TD, Thompson SM. A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice. Eneuro. 4. PMID 28275719 DOI: 10.1523/ENEURO.0285-16.2017 |
0.801 |
|
| 2017 |
Martynhak BJ, Hogben AL, Zanos P, Georgiou P, Andreatini R, Kitchen I, Archer SN, von Schantz M, Bailey A, van der Veen DR. Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3(-/-) mice, but not wildtype mice. Scientific Reports. 7: 40399. PMID 28071711 DOI: 10.1038/Srep40399 |
0.771 |
|
| 2017 |
Gould TD, Zanos P, Zarate CA. Ketamine Mechanism of Action: Separating the Wheat from the Chaff. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 42: 368-369. PMID 27909322 DOI: 10.1038/Npp.2016.210 |
0.606 |
|
| 2017 |
Camarini R, Rae M, Zanos P, Georgiou P, Chivers P, Bailey A. S14-2PARALLEL APPROACHES FOR OXYTOCIN AND ENVIRONMENTAL ENRICHMENT UPON ETHANOL’S REWARDING EFFECTS Alcohol and Alcoholism. 52: i4-i30. DOI: 10.1093/alcalc/agx075.52 |
0.768 |
|
| 2017 |
Bailey A, Georgiou P, Zanos P, Sklirou M, Kalk N, Lingford-Hughes A, Wells L. S10-1NEURO-INFLAMMATION AND ALCOHOL ADDICTION: CORRELATION WITH MEMORY AND MOTOR IMPAIRMENT Alcohol and Alcoholism. 52: i4-i30. DOI: 10.1093/alcalc/agx075.35 |
0.758 |
|
| 2017 |
Zanos P, Moaddel R, Morris P, Georgiou P, Fischell J, Elmer G, Alkondon M, Yuan P, Pribut H, Singh N, Dossou K, Fang Y, Huang X, Mayo C, Wainer I, et al. 790. Ketamine Exerts NMDAR Inhibition-Independent Antidepressant Actions via Its Hydroxynorketamine Metabolites Biological Psychiatry. 81: S321. DOI: 10.1016/J.Biopsych.2017.02.857 |
0.787 |
|
| 2017 |
Zarate C, Gould T, Zanos P, Machado-Vieira R. 80. Theories on the Mechanism of Action of Ketamine: From NMDA Receptor Inhibition to the (2R,6R)-HNK Metabolite Biological Psychiatry. 81: S33-S34. DOI: 10.1016/J.Biopsych.2017.02.092 |
0.65 |
|
| 2016 |
Zanos P, Moaddel R, Morris PJ, Wainer IW, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA, Gould TD. Reply to: Antidepressant Actions of Ketamine Versus Hydroxynorketamine. Biological Psychiatry. PMID 27817846 DOI: 10.1016/J.Biopsych.2016.08.039 |
0.674 |
|
| 2016 |
Zhang Y, Zanos P, Jackson I, Zhang X, Zhu X, Gould T, Vujaskovic Z. Psychological Stress Enhances Tumor Growth and Diminishes Radiation Response in Preclinical Model of Lung Cancer. International Journal of Radiation Oncology, Biology, Physics. 96: E474. PMID 27674788 DOI: 10.1016/j.ijrobp.2016.06.1819 |
0.21 |
|
| 2016 |
Can A, Zanos P, Moaddel R, Kang HJ, Dossou KS, Wainer IW, Cheer JF, Frost DO, Huang XP, Gould TD. Effects of ketamine and ketamine metabolites on evoked striatal dopamine release, dopamine receptors, and monoamine transporters. The Journal of Pharmacology and Experimental Therapeutics. PMID 27469513 DOI: 10.1124/Jpet.116.235838 |
0.808 |
|
| 2016 |
Georgiou P, Zanos P, Hourani S, Kitchen I, Bailey A. Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding. The European Journal of Neuroscience. PMID 27453431 DOI: 10.1111/Ejn.13348 |
0.782 |
|
| 2016 |
Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature. PMID 27144355 DOI: 10.1038/Nature17998 |
0.808 |
|
| 2016 |
Georgiou P, Zanos P, Garcia-Carmona JA, Hourani S, Kitchen I, Laorden ML, Bailey A. Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype. Neuropharmacology. PMID 26896754 DOI: 10.1016/J.Neuropharm.2016.02.012 |
0.812 |
|
| 2016 |
Zanos P, Georgiou P, Rojo Gonzalez L, Hourani S, Chen Y, Kitchen I, Kieffer BL, Winsky-Sommerer R, Bailey A. Emotional impairment and persistent up-regulation of mGlu5 receptor following morphine abstinence: implications of an mGlu5-MOPr interaction. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26861145 DOI: 10.1093/Ijnp/Pyw011 |
0.785 |
|
| 2015 |
Georgiou P, Zanos P, Garcia-Carmona JA, Hourani S, Kitchen I, Kieffer BL, Laorden ML, Bailey A. The oxytocin analogue carbetocin prevents priming-induced reinstatement of morphine-seeking: Involvement of dopaminergic, noradrenergic and MOPr systems. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26475574 DOI: 10.1016/J.Euroneuro.2015.09.015 |
0.808 |
|
| 2015 |
Zanos P, Piantadosi SC, Wu HQ, Pribut HJ, Dell MJ, Can A, Snodgrass HR, Zarate CA, Schwarcz R, Gould TD. The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition. The Journal of Pharmacology and Experimental Therapeutics. 355: 76-85. PMID 26265321 DOI: 10.1124/Jpet.115.225664 |
0.815 |
|
| 2015 |
Zanos P, Georgiou P, Metaxas A, Kitchen I, Winsky-Sommerer R, Bailey A. Region-specific up-regulation of oxytocin receptor binding in the brain of mice following chronic nicotine administration. Neuroscience Letters. 600: 33-7. PMID 26037668 DOI: 10.1016/J.Neulet.2015.05.054 |
0.79 |
|
| 2015 |
Zanos P, Bhat S, Terrillion CE, Smith RJ, Tonelli LH, Gould TD. Sex-dependent modulation of age-related cognitive decline by the L-type calcium channel gene Cacna1c (Cav 1.2). The European Journal of Neuroscience. PMID 25989111 DOI: 10.1111/Ejn.12952 |
0.764 |
|
| 2015 |
Wright SR, Zanos P, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. A critical role of striatal A2A R-mGlu5 R interactions in modulating the psychomotor and drug-seeking effects of methamphetamine. Addiction Biology. PMID 25975203 DOI: 10.1111/Adb.12259 |
0.799 |
|
| 2014 |
Georgiou P, Zanos P, Ehteramyan M, Hourani S, Kitchen I, Maldonado R, Bailey A. Differential regulation of mGlu5 R and ΜOPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice. Addiction Biology. PMID 25522112 DOI: 10.1111/Adb.12208 |
0.796 |
|
| 2014 |
Chao MR, Fragou D, Zanos P, Hu CW, Bailey A, Kouidou S, Kovatsi L. Epigenetically modified nucleotides in chronic heroin and cocaine treated mice. Toxicology Letters. 229: 451-7. PMID 25064621 DOI: 10.1016/J.Toxlet.2014.07.023 |
0.658 |
|
| 2014 |
Zanos P, Georgiou P, Wright SR, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 855-65. PMID 24129263 DOI: 10.1038/Npp.2013.285 |
0.798 |
|
| 2014 |
Zanos P, Wright SR, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism. Pharmacology, Biochemistry, and Behavior. 119: 72-9. PMID 23680573 DOI: 10.1016/J.Pbb.2013.05.009 |
0.81 |
|
| 2013 |
Fragou D, Zanos P, Kouidou S, Njau S, Kitchen I, Bailey A, Kovatsi L. Effect of chronic heroin and cocaine administration on global DNA methylation in brain and liver. Toxicology Letters. 218: 260-5. PMID 23454526 DOI: 10.1016/J.Toxlet.2013.01.022 |
0.726 |
|
| 2011 |
Zanos P, Alshehri M, Sahabandu T, Winsky-Sommerer R, Kitchen I, Bailey A. Persistent brain region-specific upregulation of vasopressin (V1ar) and oxytocin receptors in chronic intermittent escalating dose morphine administration in mice Pharmacological Reports. 63: 252. DOI: 10.1016/S1734-1140(11)70477-7 |
0.778 |
|
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