| Year |
Citation |
Score |
| 2024 |
Vano LJ, McCutcheon RA, Rutigliano G, Kaar SJ, Finelli V, Nordio G, Wellby G, Sedlacik J, Statton B, Rabiner EA, Ye R, Veronese M, Hopkins SC, Koblan KS, Everall IP, ... Howes OD, et al. Mesostriatal Dopaminergic Circuit Dysfunction in Schizophrenia: A Multimodal Neuromelanin-sensitive MRI and [18F]-DOPA PET Study. Biological Psychiatry. PMID 38942349 DOI: 10.1016/j.biopsych.2024.06.013 |
0.363 |
|
| 2024 |
Sportelli L, Eisenberg DP, Passiatore R, D'Ambrosio E, Antonucci LA, Bettina JS, Chen Q, Goldman AL, Gregory MD, Griffiths K, Hyde TM, Kleinman JE, Pardiñas AF, Parihar M, Popolizio T, ... ... Howes OD, et al. Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo. Nature Communications. 15: 3342. PMID 38688917 DOI: 10.1038/s41467-024-47456-5 |
0.352 |
|
| 2024 |
Zahid U, McCutcheon RA, Borgan F, Jauhar S, Pepper F, Nour MM, Rogdaki M, Osugo M, Murray GK, Hathway P, Murray RM, Egerton A, Howes OD. Corrigendum: The effect of antipsychotics on glutamate levels in the anterior cingulate cortex and clinical response: a H-MRS study in first-episode psychosis patients. Frontiers in Psychiatry. 15: 1292075. PMID 38495905 DOI: 10.3389/fpsyt.2024.1292075 |
0.631 |
|
| 2024 |
Arumuham A, Nour MM, Veronese M, Beck K, Onwordi EC, Lythgoe DJ, Jauhar S, Rabiner EA, Howes OD. Histamine-3 Receptor Availability and Glutamate Levels in the Brain: A PET-1H-MRS Study of Patients With Schizophrenia and Healthy Controls. The International Journal of Neuropsychopharmacology. 27. PMID 38373256 DOI: 10.1093/ijnp/pyae011 |
0.681 |
|
| 2024 |
Connolly A, Wallman P, Dzahini O, Howes O, Taylor D. Meta-analysis and systematic review of vesicular monoamine transporter (VMAT-2) inhibitors in schizophrenia and psychosis. Psychopharmacology. 241: 225-241. PMID 38238580 DOI: 10.1007/s00213-023-06488-3 |
0.322 |
|
| 2023 |
Howes OD, Bukala BR, Beck K. Schizophrenia: from neurochemistry to circuits, symptoms and treatments. Nature Reviews. Neurology. 20: 22-35. PMID 38110704 DOI: 10.1038/s41582-023-00904-0 |
0.362 |
|
| 2023 |
Xie C, Xiang S, Zheng Y, Shen C, Peng X, Li Y, Cheng W, Chang X, Cheng J, Cui LB, Huang CC, Kuang N, Li C, Lin CP, Luo C, ... ... Howes OD, et al. Dopaminergic-related Anatomical Pattern of Dorsal Striatum in Schizophrenia. Medrxiv : the Preprint Server For Health Sciences. PMID 38077063 DOI: 10.1101/2023.11.30.23298956 |
0.334 |
|
| 2023 |
Petty A, Garcia-Hidalgo A, Halff EF, Natesan S, Withers DJ, Irvine EE, Kokkinou M, Wells LA, Bonsall DR, Tang SP, Veronese M, Howes OD. Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study. Molecular Imaging and Biology. PMID 37872462 DOI: 10.1007/s11307-023-01865-y |
0.354 |
|
| 2023 |
Mizuno Y, Ashok AH, Bhat BB, Jauhar S, Howes OD. Dopamine in major depressive disorder: A systematic review and meta-analysis of in vivo imaging studies. Journal of Psychopharmacology (Oxford, England). 2698811231200881. PMID 37811803 DOI: 10.1177/02698811231200881 |
0.699 |
|
| 2023 |
Pillinger T, Howes OD, Correll CU, Leucht S, Huhn M, Schneider-Thoma J, Gaughran F, Jauhar S, McGuire PK, Taylor DM, Young AH, McCutcheon RA. Antidepressant and antipsychotic side-effects and personalised prescribing: a systematic review and digital tool development. The Lancet. Psychiatry. 10: 860-876. PMID 37774723 DOI: 10.1016/S2215-0366(23)00262-6 |
0.355 |
|
| 2023 |
Shatalina E, Ashok AH, Wall MB, Nour MM, Myers J, Reis Marques T, Rabiner EA, Howes OD. Reward processing in schizophrenia and its relation to Mu opioid receptor availability and negative symptoms: A [C]-carfentanil PET and fMRI study. Neuroimage. Clinical. 39: 103481. PMID 37517175 DOI: 10.1016/j.nicl.2023.103481 |
0.803 |
|
| 2023 |
Arumuham A, Nour MM, Veronese M, Onwordi EC, Rabiner EA, Howes OD. The histamine system and cognitive function: An in vivo H3 receptor PET imaging study in healthy volunteers and patients with schizophrenia. Journal of Psychopharmacology (Oxford, England). 2698811231177287. PMID 37329185 DOI: 10.1177/02698811231177287 |
0.682 |
|
| 2023 |
Jauhar S, McCutcheon RA, Veronese M, Borgan F, Nour M, Rogdaki M, Pepper F, Stone JM, Egerton A, Vamvakas G, Turkheimer F, McGuire PK, Howes OD. The relationship between striatal dopamine and anterior cingulate glutamate in first episode psychosis changes with antipsychotic treatment. Translational Psychiatry. 13: 184. PMID 37253720 DOI: 10.1038/s41398-023-02479-2 |
0.721 |
|
| 2023 |
McCutcheon RA, Harrison PJ, Howes OD, McGuire PK, Taylor DM, Pillinger T. Data-driven Taxonomy for Antipsychotic Medication: A New Classification System. Biological Psychiatry. PMID 37061079 DOI: 10.1016/j.biopsych.2023.04.004 |
0.337 |
|
| 2023 |
Nordio G, Easmin R, Giacomel A, Dipasquale O, Martins D, Williams S, Turkheimer F, Howes O, Veronese M, Jauhar S, Rogdaki M, McCutcheon R, Kaar S, Vano L, Rutigliano G, et al. An automatic analysis framework for FDOPA PET neuroimaging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X231168687. PMID 37026455 DOI: 10.1177/0271678X231168687 |
0.642 |
|
| 2023 |
Oliver D, Davies C, Zelaya F, Selvaggi P, De Micheli A, Catalan A, Baldwin H, Arribas M, Modinos G, Crossley NA, Allen P, Egerton A, Jauhar S, Howes OD, McGuire P, et al. Parsing neurobiological heterogeneity of the clinical high-risk state for psychosis: A pseudo-continuous arterial spin labelling study. Frontiers in Psychiatry. 14: 1092213. PMID 36970257 DOI: 10.3389/fpsyt.2023.1092213 |
0.378 |
|
| 2023 |
Merritt K, McCutcheon RA, Aleman A, Ashley S, Beck K, Block W, Bloemen OJN, Borgan F, Boules C, Bustillo JR, Capizzano AA, Coughlin JM, David A, de la Fuente-Sandoval C, Demjaha A, ... ... Howes O, et al. Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis. Molecular Psychiatry. PMID 36806762 DOI: 10.1038/s41380-023-01991-7 |
0.408 |
|
| 2023 |
Pillinger T, Osimo EF, de Marvao A, Shah M, Francis C, Huang J, D'Ambrosio E, Firth J, Nour MM, McCutcheon RA, Pardiñas AF, Matthews PM, O'Regan DP, Howes OD. Effect of polygenic risk for schizophrenia on cardiac structure and function: a UK Biobank observational study. The Lancet. Psychiatry. PMID 36632818 DOI: 10.1016/S2215-0366(22)00403-5 |
0.657 |
|
| 2022 |
Erritzoe D, Godlewska BR, Rizzo G, Searle GE, Agnorelli C, Lewis Y, Ashok AH, Colasanti A, Boura I, Farrell C, Parfitt H, Howes O, Passchier J, Gunn RN, Politis M, et al. Brain Serotonin Release Is Reduced in Patients With Depression: A [C]Cimbi-36 Positron Emission Tomography Study With a d-Amphetamine Challenge. Biological Psychiatry. PMID 36635177 DOI: 10.1016/j.biopsych.2022.10.012 |
0.673 |
|
| 2022 |
Halff EF, Rutigliano G, Garcia-Hidalgo A, Howes OD. Trace amine-associated receptor 1 (TAAR1) agonism as a new treatment strategy for schizophrenia and related disorders. Trends in Neurosciences. PMID 36369028 DOI: 10.1016/j.tins.2022.10.010 |
0.345 |
|
| 2022 |
Angelescu I, Kaar SJ, Marques TR, Borgan F, Veronesse M, Sharman A, Sajjala A, Deakin B, Hutchison J, Large C, Howes OD. The effect of AUT00206, a Kv3 potassium channel modulator, on dopamine synthesis capacity and the reliability of [F]-FDOPA imaging in schizophrenia. Journal of Psychopharmacology (Oxford, England). 36: 1061-1069. PMID 36164687 DOI: 10.1177/02698811221122031 |
0.362 |
|
| 2022 |
Beck K, Arumuham A, Brugger S, McCutcheon RA, Veronese M, Santangelo B, McGinnity CJ, Dunn J, Kaar S, Singh N, Pillinger T, Borgan F, Sementa T, Neji R, Jauhar S, ... ... Howes OD, et al. The association between -methyl-d-aspartate receptor availability and glutamate levels: A multi-modal PET-MR brain imaging study in first-episode psychosis and healthy controls. Journal of Psychopharmacology (Oxford, England). 2698811221099643. PMID 36120998 DOI: 10.1177/02698811221099643 |
0.302 |
|
| 2022 |
Kaar SJ, Angelescu I, Nour MM, Marques TR, Sharman A, Sajjala A, Hutchison J, McGuire P, Large C, Howes OD. The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia. Psychopharmacology. 239: 3313-3323. PMID 36094619 DOI: 10.1007/s00213-022-06216-3 |
0.726 |
|
| 2022 |
Zahid U, McCutcheon RA, Borgan F, Jauhar S, Pepper F, Nour MM, Rogdaki M, Osugo M, Murray GK, Hathway P, Murray RM, Howes OD. The effect of antipsychotics on glutamate levels in the anterior cingulate cortex and clinical response: A H-MRS study in first-episode psychosis patients. Frontiers in Psychiatry. 13: 967941. PMID 36032237 DOI: 10.3389/fpsyt.2022.967941 |
0.669 |
|
| 2022 |
Howes OD, Shatalina E. Integrating the Neurodevelopmental and Dopamine Hypotheses of Schizophrenia and the Role of Cortical Excitation-Inhibition Balance. Biological Psychiatry. 92: 501-513. PMID 36008036 DOI: 10.1016/j.biopsych.2022.06.017 |
0.358 |
|
| 2022 |
Nour MM, Beck K, Liu Y, Arumuham A, Veronese M, Howes OD, Dolan RJ. Relationship Between Replay-Associated Ripples and Hippocampal -Methyl-D-Aspartate Receptors: Preliminary Evidence From a PET-MEG Study in Schizophrenia. Schizophrenia Bulletin Open. 3: sgac044. PMID 35911846 DOI: 10.1093/schizbullopen/sgac044 |
0.665 |
|
| 2022 |
Shin S, Jung WH, McCutcheon R, Veronese M, Beck K, Lee JS, Lee YS, Howes OD, Kim E, Kwon JS. The Relationship Between Frontostriatal Connectivity and Striatal Dopamine Function in Schizophrenia: An 18F-DOPA PET and Diffusion Tensor Imaging Study in Treatment Responsive and Resistant Patients. Psychiatry Investigation. 19: 570-579. PMID 35903059 DOI: 10.30773/pi.2022.0033 |
0.385 |
|
| 2022 |
D'Ambrosio E, Pergola G, Pardiñas AF, Dahoun T, Veronese M, Sportelli L, Taurisano P, Griffiths K, Jauhar S, Rogdaki M, Bloomfield MAP, Froudist-Walsh S, Bonoldi I, Walters JTR, Blasi G, ... ... Howes OD, et al. A polygenic score indexing a DRD2-related co-expression network is associated with striatal dopamine function. Scientific Reports. 12: 12610. PMID 35871219 DOI: 10.1038/s41598-022-16442-6 |
0.744 |
|
| 2022 |
Griffiths K, Egerton A, Millgate E, Anton A, Barker GJ, Deakin B, Drake R, Eliasson E, Gregory CJ, Howes OD, Kravariti E, Lawrie SM, Lewis S, Lythgoe DJ, Murphy A, et al. Impaired verbal memory function is related to anterior cingulate glutamate levels in schizophrenia: findings from the STRATA study. Schizophrenia (Heidelberg, Germany). 8: 60. PMID 35853881 DOI: 10.1038/s41537-022-00265-5 |
0.418 |
|
| 2022 |
Reid MJ, Rogdaki M, Dutan L, Hanger B, Sabad K, Nagy R, Adhya D, Baron-Cohen S, McAlonan G, Price J, Vernon AC, Howes OD, Srivastava DP. Cell line specific alterations in genes associated with dopamine metabolism and signaling in midbrain dopaminergic neurons derived from 22q11.2 deletion carriers with elevated dopamine synthesis capacity. Schizophrenia Research. PMID 35701280 DOI: 10.1016/j.schres.2022.05.010 |
0.301 |
|
| 2022 |
Rogeau A, Nordio G, Veronese M, Brown K, Nour MM, Osugo M, Jauhar S, Howes OD, McCutcheon RA. The relationship between glutamate, dopamine, and cortical gray matter: A simultaneous PET-MR study. Molecular Psychiatry. PMID 35546633 DOI: 10.1038/s41380-022-01596-6 |
0.673 |
|
| 2022 |
Krajner F, Hadaya L, McQueen G, Sendt KV, Gillespie A, Avila A, Lally J, Hedges EP, Diederen K, Howes OD, Barker GJ, Lythgoe DJ, Kempton MJ, McGuire P, MacCabe JH, et al. Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia. Npj Schizophrenia. 8: 13. PMID 35236831 DOI: 10.1038/s41537-022-00230-2 |
0.41 |
|
| 2022 |
Ribeiro D, Hallett W, Howes O, McCutcheon R, Nour MM, Tavares AAS. Assessing the impact of different penalty factors of the Bayesian reconstruction algorithm Q.Clear on in vivo low count kinetic analysis of [C]PHNO brain PET-MR studies. Ejnmmi Research. 12: 11. PMID 35184229 DOI: 10.1186/s13550-022-00883-1 |
0.617 |
|
| 2022 |
Correll CU, Abi-Dargham A, Howes O. Emerging Treatments in Schizophrenia. The Journal of Clinical Psychiatry. 83. PMID 35172048 DOI: 10.4088/JCP.SU21204IP1 |
0.341 |
|
| 2022 |
Osugo M, Whitehurst T, Shatalina E, Townsend L, O'Brien O, Mak TLA, McCutcheon R, Howes O. Dopamine partial agonists and prodopaminergic drugs for schizophrenia: Systematic review and meta-analysis of randomized controlled trials. Neuroscience and Biobehavioral Reviews. 135: 104568. PMID 35131396 DOI: 10.1016/j.neubiorev.2022.104568 |
0.326 |
|
| 2021 |
Dedic N, Dworak H, Zeni C, Rutigliano G, Howes OD. Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies. International Journal of Molecular Sciences. 22. PMID 34947997 DOI: 10.3390/ijms222413185 |
0.329 |
|
| 2021 |
Allen P, Hird EJ, Orlov N, Modinos G, Bossong M, Antoniades M, Sampson C, Azis M, Howes O, Stone J, Perez J, Broome M, Grace AA, McGuire P. Correction: Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function. Translational Psychiatry. 11: 607. PMID 34848677 DOI: 10.1038/s41398-021-01731-x |
0.507 |
|
| 2021 |
Lobo MC, Whitehurst TS, Kaar SJ, Howes OD. New and emerging treatments for schizophrenia: a narrative review of their pharmacology, efficacy and side effect profile relative to established antipsychotics. Neuroscience and Biobehavioral Reviews. 132: 324-361. PMID 34838528 DOI: 10.1016/j.neubiorev.2021.11.032 |
0.325 |
|
| 2021 |
Allen P, Hird EJ, Orlov N, Modinos G, Bossong M, Antoniades M, Sampson C, Azis M, Howes O, Stone J, Perez J, Broome M, Grace AA, McGuire P. Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function. Translational Psychiatry. 11: 579. PMID 34759289 DOI: 10.1038/s41398-021-01705-z |
0.54 |
|
| 2021 |
Marques TR, Natesan S, Rabiner EA, Searle GE, Gunn R, Howes OD, Kapur S. Adenosine A receptor in schizophrenia: an in vivo brain PET imaging study. Psychopharmacology. PMID 34175983 DOI: 10.1007/s00213-021-05900-0 |
0.362 |
|
| 2021 |
Rogdaki M, Devroye C, Ciampoli M, Veronese M, Ashok AH, McCutcheon RA, Jauhar S, Bonoldi I, Gudbrandsen M, Daly E, van Amelsvoort T, Van Den Bree M, Owen MJ, Turkheimer F, Papaleo F, ... Howes OD, et al. Correction: Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study. Molecular Psychiatry. PMID 34158623 DOI: 10.1038/s41380-021-01192-0 |
0.695 |
|
| 2021 |
McCutcheon RA, Brown K, Nour MM, Smith SM, Veronese M, Zelaya F, Osugo M, Jauhar S, Hallett W, Mehta MM, Howes OD. Dopaminergic organization of striatum is linked to cortical activity and brain expression of genes associated with psychiatric illness. Science Advances. 7. PMID 34108214 DOI: 10.1126/sciadv.abg1512 |
0.682 |
|
| 2021 |
Rogdaki M, Devroye C, Ciampoli M, Veronese M, Ashok A, McCutcheon RA, Jauhar S, Bonoldi I, Gudbrandsen M, Daly E, van Amelsvoort T, Van Den Bree M, Owen MJ, Turkheimer F, Papaleo F, ... Howes OD, et al. Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study. Molecular Psychiatry. PMID 33981004 DOI: 10.1038/s41380-021-01108-y |
0.732 |
|
| 2021 |
Modinos G, Richter A, Egerton A, Bonoldi I, Azis M, Antoniades M, Bossong M, Crossley N, Perez J, Stone JM, Veronese M, Zelaya F, Grace AA, Howes OD, Allen P, et al. Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33941857 DOI: 10.1038/s41386-021-01019-0 |
0.583 |
|
| 2021 |
Merritt K, McGuire PK, Egerton A, Aleman A, Block W, Bloemen OJN, Borgan F, Bustillo JR, Capizzano AA, Coughlin JM, De la Fuente-Sandoval C, Demjaha A, Dempster K, Do KQ, ... ... Howes OD, et al. Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data. Jama Psychiatry. PMID 33881460 DOI: 10.1001/jamapsychiatry.2021.0380 |
0.449 |
|
| 2021 |
Chen KC, Yang YK, Howes OD, Lee IH, Yeh TL, Chiu NT, Chen PS, David AS, Bramon E. Striatal dopamine D receptors in medication-naïve schizophrenia: an [I] IBZM SPECT study. Psychological Medicine. 1-9. PMID 33682657 DOI: 10.1017/S0033291720005413 |
0.361 |
|
| 2021 |
Petty A, Cui X, Ali A, Du Z, Srivastav S, Kesby JP, Kirik D, Howes O, Eyles D. Positive symptom phenotypes appear progressively in "EDiPS", a new animal model of the schizophrenia prodrome. Scientific Reports. 11: 4294. PMID 33619296 DOI: 10.1038/s41598-021-83681-4 |
0.323 |
|
| 2021 |
Ashok AH, Myers J, Frost G, Turton S, Gunn RN, Passchier J, Colasanti A, Marques TR, Nutt D, Lingford-Hughes A, Howes OD, Rabiner EA. Acute acetate administration increases endogenous opioid levels in the human brain: A [C]carfentanil molecular imaging study. Journal of Psychopharmacology (Oxford, England). 269881120965912. PMID 33406950 DOI: 10.1177/0269881120965912 |
0.669 |
|
| 2021 |
McQueen G, Sendt KV, Gillespie A, Avila A, Lally J, Vallianatou K, Chang N, Ferreira D, Borgan F, Howes OD, Barker GJ, Lythgoe DJ, Stone JM, McGuire P, MacCabe JH, et al. Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia. Schizophrenia Bulletin. PMID 33398325 DOI: 10.1093/schbul/sbaa156 |
0.457 |
|
| 2020 |
Borgan F, Kokkinou M, Howes O. The Cannabinoid CB Receptor in Schizophrenia. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 33077399 DOI: 10.1016/J.Bpsc.2020.06.018 |
0.397 |
|
| 2020 |
Gifford G, Crossley N, Morgan S, Kempton MJ, Dazzan P, Modinos G, Azis M, Samson C, Bonoldi I, Quinn B, Smart SE, Antoniades M, Bossong MG, Broome MR, Perez J, ... Howes OD, et al. Integrated metastate functional connectivity networks predict change in symptom severity in clinical high risk for psychosis. Human Brain Mapping. PMID 33048435 DOI: 10.1002/hbm.25235 |
0.51 |
|
| 2020 |
Kim S, Shin SH, Santangelo B, Veronese M, Kang SK, Lee JS, Cheon GJ, Lee W, Kwon JS, Howes OD, Kim E. Dopamine dysregulation in psychotic relapse after antipsychotic discontinuation: an [F]DOPA and [C]raclopride PET study in first-episode psychosis. Molecular Psychiatry. PMID 32929214 DOI: 10.1038/s41380-020-00879-0 |
0.339 |
|
| 2020 |
Egerton A, Murphy A, Donocik J, Anton A, Barker GJ, Collier T, Deakin B, Drake R, Eliasson E, Emsley R, Gregory CJ, Griffiths K, Kapur S, Kassoumeri L, Knight L, ... ... Howes OD, et al. Dopamine and Glutamate in Antipsychotic-Responsive Compared With Antipsychotic-Nonresponsive Psychosis: A Multicenter Positron Emission Tomography and Magnetic Resonance Spectroscopy Study (STRATA). Schizophrenia Bulletin. PMID 32910150 DOI: 10.1093/Schbul/Sbaa128 |
0.496 |
|
| 2020 |
McCutcheon RA, Jauhar S, Pepper F, Nour MM, Rogdaki M, Veronese M, Turkheimer FE, Egerton A, McGuire P, Mehta MM, Howes OD. The Topography of Striatal Dopamine and Symptoms in Psychosis: An Integrative Positron Emission Tomography and Magnetic Resonance Imaging Study. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 32653578 DOI: 10.1016/J.Bpsc.2020.04.004 |
0.722 |
|
| 2020 |
Cheng PWC, Chang WC, Lo GG, Chan KWS, Lee HME, Hui LMC, Suen YN, Leung YLE, Au Yeung KMP, Chen S, Mak KFH, Sham PC, Santangelo B, Veronese M, Ho CL, ... ... Howes OD, et al. The role of dopamine dysregulation and evidence for the transdiagnostic nature of elevated dopamine synthesis in psychosis: a positron emission tomography (PET) study comparing schizophrenia, delusional disorder, and other psychotic disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32612207 DOI: 10.1038/s41386-020-0740-x |
0.358 |
|
| 2020 |
Lamichhane S, Dickens AM, Sen P, Laurikainen H, Borgan F, Suvisaari J, Hyötyläinen T, Howes O, Hietala J, Orešič M. Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis. Schizophrenia Bulletin. PMID 32609372 DOI: 10.1093/Schbul/Sbaa087 |
0.308 |
|
| 2020 |
Howes OD, Hird EJ, Adams RA, Corlett PR, McGuire P. Aberrant Salience, Information Processing, and Dopaminergic Signaling in People at Clinical High Risk for Psychosis. Biological Psychiatry. PMID 32430200 DOI: 10.1016/J.Biopsych.2020.03.012 |
0.464 |
|
| 2020 |
Wagner E, Kane JM, Correll CU, Howes O, Siskind D, Honer WG, Lee J, Falkai P, Schneider-Axmann T, Hasan A. Clozapine Combination and Augmentation Strategies in Patients With Schizophrenia -Recommendations From an International Expert Survey Among the Treatment Response and Resistance in Psychosis (TRRIP) Working Group. Schizophrenia Bulletin. PMID 32421188 DOI: 10.1093/Schbul/Sbaa060 |
0.388 |
|
| 2020 |
Kokkinou M, Irvine EE, Bonsall DR, Natesan S, Wells LA, Smith M, Glegola J, Paul EJ, Tossell K, Veronese M, Khadayate S, Dedic N, Hopkins SC, Ungless MA, Withers DJ, ... Howes OD, et al. Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine. Molecular Psychiatry. PMID 32382134 DOI: 10.1038/s41380-020-0740-6 |
0.337 |
|
| 2020 |
Mackewn JE, Stirling J, Jeljeli S, Gould SM, Johnstone RI, Merida I, Pike LC, McGinnity CG, Beck K, Howes O, Hammers A, Marsden PK. Practical issues and limitations of brain attenuation correction on a simultaneous PET-MR scanner. Ejnmmi Physics. 7: 24. PMID 32372135 DOI: 10.1186/S40658-020-00295-X |
0.3 |
|
| 2020 |
Marques TR, Ashok AH, Angelescu I, Borgan F, Myers J, Lingford-Hughes A, Nutt DJ, Veronese M, Turkheimer FE, Howes OD. GABA-A receptor differences in schizophrenia: a positron emission tomography study using [C]Ro154513. Molecular Psychiatry. PMID 32296127 DOI: 10.1038/S41380-020-0711-Y |
0.73 |
|
| 2020 |
Li A, Zalesky A, Yue W, Howes O, Yan H, Liu Y, Fan L, Whitaker KJ, Xu K, Rao G, Li J, Liu S, Wang M, Sun Y, Song M, et al. A neuroimaging biomarker for striatal dysfunction in schizophrenia. Nature Medicine. PMID 32251404 DOI: 10.1038/S41591-020-0793-8 |
0.456 |
|
| 2020 |
Adams RA, Moutoussis M, Nour MM, Dahoun T, Lewis D, Illingworth B, Veronese M, Mathys C, de Boer L, Guitart-Masip M, Friston KJ, Howes OD, Roiser JP. Variability in Action Selection Relates to Striatal Dopamine 2/3 Receptor Availability in Humans: A PET Neuroimaging Study Using Reinforcement Learning and Active Inference Models. Cerebral Cortex (New York, N.Y. : 1991). PMID 32083297 DOI: 10.1093/Cercor/Bhz327 |
0.63 |
|
| 2020 |
Onwordi EC, Halff EF, Whitehurst T, Mansur A, Cotel MC, Wells L, Creeney H, Bonsall D, Rogdaki M, Shatalina E, Reis Marques T, Rabiner EA, Gunn RN, Natesan S, Vernon AC, ... Howes OD, et al. Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats. Nature Communications. 11: 246. PMID 31937764 DOI: 10.1038/S41467-019-14122-0 |
0.3 |
|
| 2020 |
Rogdaki M, Gudbrandsen M, McCutcheon RA, Blackmore CE, Brugger S, Ecker C, Craig MC, Daly E, Murphy DGM, Howes O. Magnitude and heterogeneity of brain structural abnormalities in 22q11.2 deletion syndrome: a meta-analysis. Molecular Psychiatry. PMID 31925327 DOI: 10.1038/S41380-019-0638-3 |
0.308 |
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| 2020 |
McCutcheon RA, Krystal JH, Howes OD. Dopamine and glutamate in schizophrenia: biology, symptoms and treatment. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 19: 15-33. PMID 31922684 DOI: 10.1002/Wps.20693 |
0.378 |
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| 2020 |
Adams R, Bush D, Zheng F, Meyer S, Kaplan R, Orfanos S, Reis Marques T, Howes O, Burgess N. S153. IMPAIRED THETA PHASE-COUPLING BETWEEN HIPPOCAMPUS AND MEDIAL PREFRONTAL CORTEX IN SCHIZOPHRENIA Schizophrenia Bulletin. 46: S94-S94. DOI: 10.1093/Schbul/Sbaa031.219 |
0.327 |
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| 2020 |
Hird E, Allen P, Orlov N, Modinos G, Bossong M, Antoniades M, Sampson C, Azis M, Howes O, Stone J, Grace A, McGuire P. M163. GLUTAMATE METABOLITES ARE ASSOCIATED WITH ALTERED HIPPOCAMPAL ACTIVATION BUT NOT HIPPOCAMPAL-STRIATAL CONNECTIVITY IN SUBJECTS WITH A CLINICAL HIGH RISK FOR PSYCHOSIS Schizophrenia Bulletin. 46: S198-S198. DOI: 10.1093/Schbul/Sbaa030.475 |
0.468 |
|
| 2020 |
Merritt K, Aleman A, Block W, Bloemen O, Borgan F, Bustillo J, Capizzano A, Coughlin J, Fuente-Sandoval Cdl, Demjaha A, Do K, Drost D, Falkai P, Galińska B, Gallinat J, ... ... Howes O, et al. M157. A Multicentre Study Of 1H-Mrs Brain Glutamate Levels In Schizophrenia; Investigating The Effect Of Antipsychotic Medication, Symptom Severity And Age Schizophrenia Bulletin. 46. DOI: 10.1093/Schbul/Sbaa030.469 |
0.378 |
|
| 2020 |
McCutcheon R, Jauhar S, Pepper F, Nour M, Rogdaki M, Veronese M, Turkheimer F, Egerton A, McGuire P, Mehta M, Howes O. M149. THE TOPOGRAPHY OF STRIATAL DOPAMINE AND SYMPTOMS IN PSYCHOSIS: AN INTEGRATIVE PET AND MRI STUDY Schizophrenia Bulletin. 46: S192-S192. DOI: 10.1093/Schbul/Sbaa030.461 |
0.751 |
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| 2020 |
Pillinger T, McCutcheon R, Efthimiou O, Cipriani A, Howes O. T79. Balancing Effects With Side-Effects: Examining Comparative Metabolic Consequences Of 18 Antipsychotics In Treatment Of Schizophrenia Using Network Meta-Analysis Schizophrenia Bulletin. 46. DOI: 10.1093/Schbul/Sbaa029.639 |
0.36 |
|
| 2020 |
McCutcheon R, Pillinger T, Mizuno Y, Montgomery A, Pandian H, Vano L, Marques TR, Howes O. T45. The Efficacy And Heterogeneity Of Antipsychotic Response In Schizophrenia: A Meta-Analysis Schizophrenia Bulletin. 46. DOI: 10.1093/Schbul/Sbaa029.605 |
0.372 |
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| 2020 |
Egerton A, McQueen G, Sendt K, Gillespie A, Lally J, Borgan F, Howes O, Barker GJ, Stone J, McGuire P, MacCabe J. T19. GLUTAMATE AND RESPONSE TO CLOZAPINE IN TREATMENT RESISTANT SCHIZOPHRENIA Schizophrenia Bulletin. 46: S238-S238. DOI: 10.1093/Schbul/Sbaa029.579 |
0.513 |
|
| 2020 |
Plavén-Sigray P, Matheson G, Coughlin J, Hafizi S, Laurikainen H, Ottoy J, de’Picker L, Rusjan P, Hietala J, Howes O, Mizrahi R, Morrens M, Pomper M, Cervenka S. T7. UPDATED INDIVIDUAL PARTICIPANT DATA META-ANALYSIS CONFIRMS LOWER LEVELS OF THE GLIAL MARKER TSPO IN PSYCHOSIS PATIENTS Schizophrenia Bulletin. 46: S233-S233. DOI: 10.1093/Schbul/Sbaa029.567 |
0.373 |
|
| 2020 |
Howes O, Ashok A, Shatalina E, Rabiner E, Marques TR. O5.5. The Neurobiology Of Negative Symptoms In Schizophrenia: Multi-Modal Pet And Fmri Findings Schizophrenia Bulletin. 46. DOI: 10.1093/Schbul/Sbaa028.028 |
0.806 |
|
| 2020 |
Howes O, Onwordi E, Haalf E, Whitehurst T, Wells L, Rabiner I, Bonsall D, Vernon A. The Synaptic Hypothesis of Schizophrenia: In Vivo PET Evidence in Patients and Preclinical Evidence of the Effects of Antipsychotics Biological Psychiatry. 87: S234. DOI: 10.1016/J.Biopsych.2020.02.607 |
0.421 |
|
| 2020 |
Howes O. The Role of Glutamate and GABA in Regulating Striatal Dopamine Synthesis Capacity and Therapeutic Implications Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.273 |
0.332 |
|
| 2019 |
Modinos G, Allen P, Zugman A, Dima D, Azis M, Samson C, Bonoldi I, Quinn B, Gifford GWG, Smart SE, Antoniades M, Bossong MG, Broome MR, Perez J, Howes OD, et al. Neural Circuitry of Novelty Salience Processing in Psychosis Risk: Association With Clinical Outcome. Schizophrenia Bulletin. PMID 32227226 DOI: 10.1093/Schbul/Sbz089 |
0.563 |
|
| 2019 |
Borgan F, O'Daly O, Veronese M, Reis Marques T, Laurikainen H, Hietala J, Howes O. The neural and molecular basis of working memory function in psychosis: a multimodal PET-fMRI study. Molecular Psychiatry. PMID 31801965 DOI: 10.1038/s41380-019-0619-6 |
0.329 |
|
| 2019 |
Erritzoe D, Ashok AH, Searle GE, Colasanti A, Turton S, Lewis Y, Huiban M, Moz S, Passchier J, Saleem A, Beaver J, Lingford-Hughes A, Nutt DJ, Howes OD, Gunn RN, et al. Serotonin release measured in the human brain: a PET study with [C]CIMBI-36 and d-amphetamine challenge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31715617 DOI: 10.1038/S41386-019-0567-5 |
0.693 |
|
| 2019 |
Dahoun T, Nour MM, McCutcheon RA, Adams RA, Bloomfield MAP, Howes OD. The relationship between childhood trauma, dopamine release and dexamphetamine-induced positive psychotic symptoms: a [C]-(+)-PHNO PET study. Translational Psychiatry. 9: 287. PMID 31712556 DOI: 10.1038/s41398-019-0627-y |
0.677 |
|
| 2019 |
Bloomfield MA, McCutcheon RA, Kempton M, Freeman TP, Howes O. The effects of psychosocial stress on dopaminergic function and the acute stress response. Elife. 8. PMID 31711569 DOI: 10.7554/Elife.46797 |
0.333 |
|
| 2019 |
D'Ambrosio E, Jauhar S, Kim S, Veronese M, Rogdaki M, Pepper F, Bonoldi I, Kotoula V, Kempton MJ, Turkheimer F, Kwon JS, Kim E, Howes OD. The relationship between grey matter volume and striatal dopamine function in psychosis: a multimodal F-DOPA PET and voxel-based morphometry study. Molecular Psychiatry. PMID 31690805 DOI: 10.1038/s41380-019-0570-6 |
0.374 |
|
| 2019 |
Rogdaki M, Hathway P, Gudbrandsen M, McCutcheon RA, Jauhar S, Daly E, Howes O. Glutamatergic function in a genetic high-risk group for psychosis: A proton magnetic resonance spectroscopy study in individuals with 22q11.2 deletion. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 31648854 DOI: 10.1016/J.Euroneuro.2019.09.005 |
0.375 |
|
| 2019 |
Howes OD, Bonoldi I, McCutcheon RA, Azis M, Antoniades M, Bossong M, Modinos G, Perez J, Stone JM, Santangelo B, Veronese M, Grace A, Allen P, McGuire PK. Glutamatergic and dopaminergic function and the relationship to outcome in people at clinical high risk of psychosis: a multi-modal PET-magnetic resonance brain imaging study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31618752 DOI: 10.1038/s41386-019-0541-2 |
0.621 |
|
| 2019 |
Ashok AH, Myers J, Reis Marques T, Rabiner EA, Howes OD. Reduced mu opioid receptor availability in schizophrenia revealed with [C]-carfentanil positron emission tomographic Imaging. Nature Communications. 10: 4493. PMID 31582737 DOI: 10.1038/S41467-019-12366-4 |
0.742 |
|
| 2019 |
Brugger SP, Angelescu I, Abi-Dargham A, Mizrahi R, Shahrezaei V, Howes OD. Heterogeneity of Striatal Dopamine Function in Schizophrenia: Meta-analysis of Variance. Biological Psychiatry. PMID 31561858 DOI: 10.1016/J.Biopsych.2019.07.008 |
0.356 |
|
| 2019 |
D'Ambrosio E, Dahoun T, Pardiñas AF, Veronese M, Bloomfield MAP, Jauhar S, Bonoldi I, Rogdaki M, Froudist-Walsh S, Walters JTR, Howes OD. The effect of a genetic variant at the schizophrenia associated AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging study. Psychiatry Research. Neuroimaging. 291: 34-41. PMID 31386983 DOI: 10.1016/J.Pscychresns.2019.07.005 |
0.752 |
|
| 2019 |
Merritt K, Perez-Iglesias R, Sendt KV, Goozee R, Jauhar S, Pepper F, Barker GJ, Glenthøj B, Arango C, Lewis S, Kahn R, Stone J, Howes O, Dazzan P, McGuire P, et al. Remission from antipsychotic treatment in first episode psychosis related to longitudinal changes in brain glutamate. Npj Schizophrenia. 5: 12. PMID 31371817 DOI: 10.1038/s41537-019-0080-1 |
0.425 |
|
| 2019 |
Kaar SJ, Natesan S, McCutcheon R, Howes OD. Antipsychotics: mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology. Neuropharmacology. 107704. PMID 31299229 DOI: 10.1016/j.neuropharm.2019.107704 |
0.357 |
|
| 2019 |
Nour MM, Dahoun T, McCutcheon RA, Adams RA, Wall MB, Howes OD. Task-induced functional brain connectivity mediates the relationship between striatal D2/3 receptors and working memory. Elife. 8. PMID 31290741 DOI: 10.7554/eLife.45045 |
0.633 |
|
| 2019 |
Borgan F, Laurikainen H, Veronese M, Marques TR, Haaparanta-Solin M, Solin O, Dahoun T, Rogdaki M, Salokangas RK, Karukivi M, Di Forti M, Turkheimer F, Hietala J, Howes O. In Vivo Availability of Cannabinoid 1 Receptor Levels in Patients With First-Episode Psychosis. Jama Psychiatry. PMID 31268519 DOI: 10.1001/Jamapsychiatry.2019.1427 |
0.349 |
|
| 2019 |
Dahoun T, Nour MM, Adams RA, Trossbach S, Lee SH, Patel H, Curtis C, Korth C, Howes OD. Disrupted-in-Schizophrenia 1 (DISC1) functional polymorphisms and D /D receptor availability: a [ C]-(+)-PHNO imaging study. Genes, Brain, and Behavior. e12596. PMID 31264367 DOI: 10.1111/gbb.12596 |
0.654 |
|
| 2019 |
Bonoldi I, Allen P, Madeira L, Tognin S, Bossong MG, Azis M, Samson C, Quinn B, Calem M, Valmaggia L, Modinos G, Stone J, Perez J, Howes O, Politi P, et al. Basic Self-Disturbances Related to Reduced Anterior Cingulate Volume in Subjects at Ultra-High Risk for Psychosis. Frontiers in Psychiatry. 10: 254. PMID 31133887 DOI: 10.3389/Fpsyt.2019.00254 |
0.437 |
|
| 2019 |
Petty A, Cui X, Tesiram Y, Kirik D, Howes O, Eyles D. Enhanced Dopamine in Prodromal Schizophrenia (EDiPS): a new animal model of relevance to schizophrenia. Npj Schizophrenia. 5: 6. PMID 30926827 DOI: 10.1038/s41537-019-0074-z |
0.354 |
|
| 2019 |
Ashok AH, Mizuno Y, Howes OD. Tobacco smoking and dopaminergic function in humans: a meta-analysis of molecular imaging studies. Psychopharmacology. PMID 30887059 DOI: 10.1007/S00213-019-05196-1 |
0.65 |
|
| 2019 |
Kane JM, Agid O, Baldwin ML, Howes O, Lindenmayer JP, Marder S, Olfson M, Potkin SG, Correll CU. Clinical Guidance on the Identification and Management of Treatment-Resistant Schizophrenia. The Journal of Clinical Psychiatry. 80. PMID 30840788 DOI: 10.4088/Jcp.18Com12123 |
0.381 |
|
| 2019 |
Veronese M, Moro L, Arcolin M, Dipasquale O, Rizzo G, Expert P, Khan W, Fisher PM, Svarer C, Bertoldo A, Howes O, Turkheimer FE. Covariance statistics and network analysis of brain PET imaging studies. Scientific Reports. 9: 2496. PMID 30792460 DOI: 10.1038/S41598-019-39005-8 |
0.321 |
|
| 2019 |
McCutcheon RA, Abi-Dargham A, Howes OD. Schizophrenia, Dopamine and the Striatum: From Biology to Symptoms. Trends in Neurosciences. PMID 30621912 DOI: 10.1016/j.tins.2018.12.004 |
0.367 |
|
| 2019 |
Hutchison J, Howes O, Marques TR, Kaar S, van den Berg F, Large C. 32.4 A NOVEL TREATMENT FOR COGNITIVE IMPAIRMENT ASSOCIATED WITH SCHIZOPHRENIA BY ENHANCING THE ACTIVITY OF PARVALBUMIN INTERNEURONS Schizophrenia Bulletin. 45: S142-S143. DOI: 10.1093/Schbul/Sbz022.135 |
0.354 |
|
| 2019 |
Borgan F, Laurikainen H, Hietala J, Howes O. 20.2 CANNABINOID 1 RECEPTOR AVAILABILITY AND MEMORY FUNCTION IN FIRST EPISODE PSYCHOSIS: A MULTI-MODAL PET AND FUNCTIONAL MRI IMAGING STUDY Schizophrenia Bulletin. 45: S122-S122. DOI: 10.1093/Schbul/Sbz022.081 |
0.323 |
|
| 2019 |
Allen P, Modinos G, Bossong M, Antoniades M, Samson C, Azis M, Howes O, Stone J, Grace A, McGuire P. O13.5. GLUTAMATERGIC METABOLITES ASSOCIATED WITH ALTERED HIPPOCAMPAL AND STRIATAL ACTIVATION DURING NOVELTY SALIENCE IN PEOPLE WITH A CLINICAL HIGH RISK FOR PSYCHOSIS Schizophrenia Bulletin. 45: S202-S203. DOI: 10.1093/Schbul/Sbz021.277 |
0.575 |
|
| 2019 |
Marques TR, Ashok A, Veronese M, Ureche-Angelescu I, Borgan F, Rabiner E, Howes O. O7.6. GABAA RECEPTOR AVAILABILITY IN PATIENTS WITH SCHIZOPHRENIA: A PET STUDY USING [11C]-RO15 Schizophrenia Bulletin. 45: S181-S182. DOI: 10.1093/Schbul/Sbz021.230 |
0.802 |
|
| 2019 |
Modinos G, Allen P, Zugman A, Dima D, Azis M, Samson C, Bonoldi I, Quinn B, Gifford G, Smart S, Antoniades M, Bossong M, Broome MR, Perez J, Howes OD, et al. O7.3. ALTERED HIPPOCAMPAL-STRIATAL-MIDBRAIN FUNCTION IN SUBJECTS AT CLINICAL HIGH RISK OF PSYCHOSIS Schizophrenia Bulletin. 45: S180-S180. DOI: 10.1093/Schbul/Sbz021.227 |
0.523 |
|
| 2019 |
Merritt K, Perez-Iglesias R, Sendt K, Goozee R, Jauhar S, Pepper F, Barker GJ, Glenthoj B, Arango C, Lewis S, Kahn R, Stone J, Howes O, Dazzan P, McGuire P, et al. O5.6. REMISSION FROM ANTIPSYCHOTIC TREATMENT IN FIRST EPISODE PSYCHOSIS RELATED TO LONGITUDINAL CHANGES IN BRAIN GLUTAMATE LEVELS Schizophrenia Bulletin. 45: S175-S175. DOI: 10.1093/Schbul/Sbz021.214 |
0.458 |
|
| 2019 |
Kokkinou M, Howes O. O2.1. CIRCUIT MECHANISM MEDIATES THE EFFECTS OF SUB-CHRONIC KETAMINE ON STRIATAL DOPAMINE SYNTHESIS CAPACITY AND LOCOMOTOR ACTIVITY: A COMBINED CHEMOGENETICS/PET STUDY Schizophrenia Bulletin. 45: S162-S162. DOI: 10.1093/Schbul/Sbz021.185 |
0.356 |
|
| 2019 |
Zahid U, Jauhar S, Pepper F, McCutcheon R, Borgan F, Nour M, Rogdaki M, Hathway P, Murray R, Howes O. S84. THE EFFECT OF ANTIPSYCHOTICS ON GLUTAMATE LEVELS IN THE ANTERIOR CINGULATE AND CLINICAL RESPONSE MEASURED BY PANSS: A 1H-MRS STUDY IN FIRST-EPISODE PSYCHOSIS PATIENTS Schizophrenia Bulletin. 45: S339-S339. DOI: 10.1093/Schbul/Sbz020.629 |
0.666 |
|
| 2019 |
Bloomfield M, Modaffar M, Howes O. F107. THE EFFECTS OF DEVELOPMENTAL STRESS AND TRAUMA ON THE DOPAMINE SYSTEM Schizophrenia Bulletin. 45: S294-S294. DOI: 10.1093/Schbul/Sbz018.519 |
0.317 |
|
| 2019 |
Howes O, Ashok A, Pepper F, Jauhar S, Marques TR. F80. THE NEUROBIOLOGY OF NEGATIVE SYMPTOMS: PET AND MR IMAGING FINDINGS IN FIRST EPISODE AND CHRONIC SCHIZOPHRENIA Schizophrenia Bulletin. 45: S284-S284. DOI: 10.1093/Schbul/Sbz018.492 |
0.742 |
|
| 2019 |
Osimo EF, Brugger S, Howes O. P.4.06 Treatment with clozapine and olanzapine and cardiac changes in patients with schizophrenia: An MRI study European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.01.096 |
0.38 |
|
| 2019 |
Beck K, Borgan F, McCutcheon R, Hindley G, Taylor M, Howes O. The effect of ketamine on psychopathology and implications for understanding schizophrenia: a meta-analysis European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.11.900 |
0.402 |
|
| 2019 |
McCutcheon R, Nour M, Dahoun T, Jauhar S, Expert P, Mehta M, Howes O. Mesolimbic dopamine function and salience network connectivity: An integrative PET and MR study European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.11.881 |
0.684 |
|
| 2018 |
Kim S, Jung WH, Howes OD, Veronese M, Turkheimer FE, Lee YS, Lee JS, Kim E, Kwon JS. Frontostriatal functional connectivity and striatal dopamine synthesis capacity in schizophrenia in terms of antipsychotic responsiveness: an [18F]DOPA PET and fMRI study. Psychological Medicine. 1-10. PMID 30460891 DOI: 10.1017/S0033291718003471 |
0.383 |
|
| 2018 |
Bossong MG, Antoniades M, Azis M, Samson C, Quinn B, Bonoldi I, Modinos G, Perez J, Howes OD, Stone JM, Allen P, McGuire P. Association of Hippocampal Glutamate Levels With Adverse Outcomes in Individuals at Clinical High Risk for Psychosis. Jama Psychiatry. PMID 30427993 DOI: 10.1001/Jamapsychiatry.2018.3252 |
0.439 |
|
| 2018 |
McCutcheon RA, Nour MM, Dahoun T, Jauhar S, Pepper F, Expert P, Veronese M, Adams RA, Turkheimer F, Mehta MA, Howes OD. Mesolimbic Dopamine Function Is Related to Salience Network Connectivity: An Integrative Positron Emission Tomography and Magnetic Resonance Study. Biological Psychiatry. PMID 30389131 DOI: 10.1016/J.Biopsych.2018.09.010 |
0.664 |
|
| 2018 |
Onwordi E, Howes O. Trends in mortality in schizophrenia and their implications. Acta Psychiatrica Scandinavica. 138: 489-491. PMID 30374964 DOI: 10.1111/Acps.12977 |
0.362 |
|
| 2018 |
Marques TR, Ashok AH, Pillinger T, Veronese M, Turkheimer FE, Dazzan P, Sommer IEC, Howes OD. Neuroinflammation in schizophrenia: meta-analysis of in vivo microglial imaging studies. Psychological Medicine. 1-11. PMID 30355368 DOI: 10.1017/S0033291718003057 |
0.722 |
|
| 2018 |
Nour MM, Dahoun T, Schwartenbeck P, Adams RA, FitzGerald THB, Coello C, Wall MB, Dolan RJ, Howes OD. Dopaminergic basis for signaling belief updates, but not surprise, and the link to paranoia. Proceedings of the National Academy of Sciences of the United States of America. PMID 30297411 DOI: 10.1073/pnas.1809298115 |
0.662 |
|
| 2018 |
Laurikainen H, Tuominen L, Tikka M, Merisaari H, Armio RL, Sormunen E, Borgan F, Veronese M, Howes O, Haaparanta-Solin M, Solin O, Hietala J. Sex difference in brain CB1 receptor availability in man. Neuroimage. 184: 834-842. PMID 30296558 DOI: 10.1016/J.Neuroimage.2018.10.013 |
0.328 |
|
| 2018 |
Modinos G, Şimşek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, et al. Correction: Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30279560 DOI: 10.1038/S41386-018-0118-5 |
0.5 |
|
| 2018 |
Jauhar S, McCutcheon R, Borgan F, Veronese M, Nour M, Pepper F, Rogdaki M, Stone J, Egerton A, Turkheimer F, McGuire P, Howes OD. The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: a cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study. The Lancet. Psychiatry. PMID 30236864 DOI: 10.1016/S2215-0366(18)30268-2 |
0.719 |
|
| 2018 |
Bloomfield PS, Bonsall D, Wells L, Dormann D, Howes O, Paola V. The effects of haloperidol on microglial morphology and translocator protein levels: An in vivo study in rats using an automated cell evaluation pipeline. Journal of Psychopharmacology (Oxford, England). 269881118788830. PMID 30126329 DOI: 10.1177/0269881118788830 |
0.377 |
|
| 2018 |
Jauhar S, Veronese M, Nour MM, Rogdaki M, Hathway P, Natesan S, Turkheimer F, Stone J, Egerton A, McGuire P, Kapur S, Howes OD. The Effects of Antipsychotic Treatment on Presynaptic Dopamine Synthesis Capacity in First-Episode Psychosis: A Positron Emission Tomography Study. Biological Psychiatry. PMID 30122287 DOI: 10.1016/J.Biopsych.2018.07.003 |
0.733 |
|
| 2018 |
Dahoun T, Pardiñas AF, Veronese M, Bloomfield MAP, Jauhar S, Bonoldi I, Froudist-Walsh S, Nosarti C, Korth C, Hennah W, Walters J, Prata D, Howes OD. The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study. Human Molecular Genetics. PMID 29945223 DOI: 10.1093/Hmg/Ddy242 |
0.772 |
|
| 2018 |
Shin S, Kim S, Seo S, Lee JS, Howes OD, Kim E, Kwon JS. The relationship between dopamine receptor blockade and cognitive performance in schizophrenia: a [C]-raclopride PET study with aripiprazole. Translational Psychiatry. 8: 87. PMID 29686254 DOI: 10.1038/s41398-018-0134-6 |
0.331 |
|
| 2018 |
Jauhar S, Veronese M, Nour MM, Rogdaki M, Hathway P, Turkheimer FE, Stone J, Egerton A, McGuire P, Kapur S, Howes OD. Determinants of treatment response in first-episode psychosis: an F-DOPA PET study. Molecular Psychiatry. PMID 29679071 DOI: 10.1038/S41380-018-0042-4 |
0.711 |
|
| 2018 |
Nour MM, McCutcheon R, Howes OD. The Relationship Between Dopamine Synthesis Capacity and Release: Implications for Psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 43: 1195-1196. PMID 29670249 DOI: 10.1038/npp.2017.293 |
0.651 |
|
| 2018 |
Plavén-Sigray P, Matheson GJ, Collste K, Ashok AH, Coughlin JM, Howes OD, Mizrahi R, Pomper MG, Rusjan P, Veronese M, Wang Y, Cervenka S. Positron Emission Tomography Studies of the Glial Cell Marker Translocator Protein in Patients With Psychosis: A Meta-analysis Using Individual Participant Data. Biological Psychiatry. PMID 29653835 DOI: 10.1016/J.Biopsych.2018.02.1171 |
0.713 |
|
| 2018 |
Modinos G, Şimşek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, et al. Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29440719 DOI: 10.1038/S41386-017-0004-6 |
0.522 |
|
| 2018 |
Rogdaki M, Veronese M, Hathway P, Jauhar S, Gudbrandsen M, Daly E, Howes O. S181. The State Or Trait Component Of Dopamine And Glutamate Dysfunction In The Risk For Psychosis: An In Vivo Multimodal Imaging Study Of Individuals With 22Q11.2 Deletion Schizophrenia Bulletin. 44. DOI: 10.1093/Schbul/Sby018.968 |
0.366 |
|
| 2018 |
Nour M, Dahoun T, Schwartenbeck P, Adams R, FitzGerald T, Coello C, Wall M, Dolan R, Howes O. S154. THE ROLE OF DOPAMINE IN PROCESSING THE MEANINGFUL INFORMATION OF OBSERVATIONS, AND IMPLICATIONS FOR THE ABERRANT SALIENCE HYPOTHESIS OF SCHIZOPHRENIA Schizophrenia Bulletin. 44: S385-S385. DOI: 10.1093/Schbul/Sby018.941 |
0.716 |
|
| 2018 |
Borgan F, Veronese M, O’Daly O, Marques TR, Rogdaki M, Howes O. F180. Cannabinoid 1 Receptor Availability & Memory Function In First Episode Psychosis: A Multi-Modal Pet-Fmri Study Schizophrenia Bulletin. 44. DOI: 10.1093/Schbul/Sby017.711 |
0.318 |
|
| 2018 |
Pillinger T, D’Ambrosio E, McCutcheon R, Howes O. F18. Is Schizophrenia A Multi-System Disorder? Considering Neurological, Immune, Cardiometabolic, And Endocrine Alterations In First Episode Psychosis. Schizophrenia Bulletin. 44. DOI: 10.1093/Schbul/Sby017.549 |
0.309 |
|
| 2018 |
Kokkinou M, Howes O. O7.1. Midbrain Dopamine Neuron Activity Controls The Effects Of Repeated Ketamine On Striatal Dopaminergic Function. Schizophrenia Bulletin. 44. DOI: 10.1093/Schbul/Sby015.230 |
0.414 |
|
| 2018 |
Jauhar S, Nour M, Veronese M, Rogdaki M, Bonoldi I, Azis M, Turkheimer F, McGuire P, Howes O. O3.5. TESTING THE DOPAMINE HYPOTHESIS OF PSYCHOSIS USING POSITRON EMISSION TOMOGRAPHIC IMAGING IN FIRST EPISODE BIPOLAR AFFECTIVE DISORDER AND SCHIZOPHRENIA Schizophrenia Bulletin. 44: S81-S81. DOI: 10.1093/Schbul/Sby015.203 |
0.767 |
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| 2018 |
Howes O, Jauhar S, Brugger S, Pepper F. 9.2 Brain Structural And Neurochemical Heterogeneity And Homogeneity In Psychotic Disorders: Transdiagnostic Pet And Mri Imaging Findings In Schizophrenia And Bipolar Affective Disorder Schizophrenia Bulletin. 44. DOI: 10.1093/Schbul/Sby014.030 |
0.48 |
|
| 2018 |
Nour M, Dahoun T, Schwartenbeck P, Adams R, Coello C, Wall M, FitzGerald T, Dolan R, Howes O. Dopamine modulates belief updating but not surprise in the midbrain and ventral striatum European Neuropsychopharmacology. 28. DOI: 10.1016/J.Euroneuro.2017.12.048 |
0.704 |
|
| 2018 |
Borgan F, Veronese M, Marques T, Rogdaki M, Howes O. F229. Cannabinoid 1 Receptor and Memory Function in First Episode Psychosis: A Multi-Modal PET-fMRI Study Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.843 |
0.317 |
|
| 2018 |
Rogdaki M, Veronese M, Hathaway P, Jauhar S, Maria G, Eileen D, Howes O. F227. The State or Trait Component of Dopamine and Glutamate Dysfunction in the Risk for Psychosis: An in Vivo Multimodal Imaging Study of Individuals With 22q11 Deletion Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.841 |
0.374 |
|
| 2018 |
Jauhar S, McCutcheon R, Veronese M, Rogdaki M, Nour M, Stone JM, Pepper F, Egerton A, McGuire P, Howes O. F226. The Relationship Between Cortical Glutamate and Striatal Dopamine Function in Psychosis: A Multi-Modal PET and MRS Imaging Study in First Episode Psychosis Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.840 |
0.74 |
|
| 2018 |
Howes O, Nour M, Pepper F, Jauhar S. 249. Dopaminergic and Glutamatergic Function in Bipolar Disorder and Schizophrenia and Treatment Response: PET and MRS Evidence in Drug Naive Patients Biological Psychiatry. 83: S100-S101. DOI: 10.1016/J.Biopsych.2018.02.268 |
0.71 |
|
| 2017 |
McCutcheon R, Beck K, Jauhar S, Howes OD. Defining the Locus of Dopaminergic Dysfunction in Schizophrenia: A Meta-analysis and Test of the Mesolimbic Hypothesis. Schizophrenia Bulletin. PMID 29301039 DOI: 10.1093/schbul/sbx180 |
0.391 |
|
| 2017 |
Allen P, Azis M, Modinos G, Bossong MG, Bonoldi I, Samson C, Quinn B, Kempton MJ, Howes OD, Stone JM, Calem M, Perez J, Bhattacharayya S, Broome MR, Grace AA, et al. Increased Resting Hippocampal and Basal Ganglia Perfusion in People at Ultra High Risk for Psychosis: Replication in a Second Cohort. Schizophrenia Bulletin. PMID 29294102 DOI: 10.1093/Schbul/Sbx169 |
0.553 |
|
| 2017 |
Froudist-Walsh S, Bloomfield MA, Veronese M, Kroll J, Karolis VR, Jauhar S, Bonoldi I, McGuire PK, Kapur S, Murray RM, Nosarti C, Howes O. The effect of perinatal brain injury on dopaminergic function and hippocampal volume in adult life. Elife. 6. PMID 29179814 DOI: 10.7554/Elife.29088 |
0.781 |
|
| 2017 |
Bhattacharyya S, Egerton A, Kim E, Rosso L, Riano Barros D, Hammers A, Brammer M, Turkheimer FE, Howes OD, McGuire P. Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors. Scientific Reports. 7: 15025. PMID 29101333 DOI: 10.1038/S41598-017-14203-4 |
0.348 |
|
| 2017 |
Jauhar S, Nour MM, Veronese M, Rogdaki M, Bonoldi I, Azis M, Turkheimer F, McGuire P, Young AH, Howes OD. A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia. Jama Psychiatry. PMID 29049482 DOI: 10.1001/Jamapsychiatry.2017.2943 |
0.734 |
|
| 2017 |
Modinos G, Simsek F, Horder J, Bossong M, Bonoldi I, Azis M, Perez J, Broome M, Lythgoe DJ, Stone JM, Howes OD, Murphy DG, Grace AA, Allen P, McGuire P. Cortical GABA In Subjects At Ultra-High Risk Of Psychosis: Relationship To Negative Prodromal Symptoms. The International Journal of Neuropsychopharmacology. PMID 29020419 DOI: 10.1093/Ijnp/Pyx076 |
0.536 |
|
| 2017 |
Murray RM, Bhavsar V, Tripoli G, Howes O. 30 Years on: How the Neurodevelopmental Hypothesis of Schizophrenia Morphed into the Developmental Risk Factor Model of Psychosis. Schizophrenia Bulletin. PMID 28981842 DOI: 10.1093/Schbul/Sbx121 |
0.401 |
|
| 2017 |
Selvaraj S, Bloomfield PS, Cao B, Veronese M, Turkheimer F, Howes OD. Brain TSPO imaging and gray matter volume in schizophrenia patients and in people at ultra high risk of psychosis: An [(11)C]PBR28 study. Schizophrenia Research. PMID 28893493 DOI: 10.1016/J.Schres.2017.08.063 |
0.308 |
|
| 2017 |
Selvaraj S, Walker C, Arnone D, Cao B, Faulkner P, Cowen PJ, Roiser JP, Howes O. Effect of Citalopram on Emotion Processing in Humans: A Combined 5-HT1A [(11)C]CUMI-101 PET and Functional MRI Study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28776580 DOI: 10.1038/Npp.2017.166 |
0.533 |
|
| 2017 |
Veronese M, Reis Marques T, Bloomfield PS, Rizzo G, Singh N, Jones D, Agushi E, Mosses D, Bertoldo A, Howes O, Roncaroli F, Turkheimer FE. Kinetic modelling of [(11)C]PBR28 for 18 kDa translocator protein PET data: A validation study of vascular modelling in the brain using XBD173 and tissue analysis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17712388. PMID 28580888 DOI: 10.1177/0271678X17712388 |
0.336 |
|
| 2017 |
Ashok AH, Mizuno Y, Volkow ND, Howes OD. Association of Stimulant Use With Dopaminergic Alterations in Users of Cocaine, Amphetamine, or Methamphetamine: A Systematic Review and Meta-analysis. Jama Psychiatry. PMID 28297025 DOI: 10.1001/Jamapsychiatry.2017.0135 |
0.681 |
|
| 2017 |
Howes O, McCutcheon R. Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization Translational Psychiatry. 7. PMID 28170004 DOI: 10.1038/Tp.2016.278 |
0.378 |
|
| 2017 |
Egerton A, Howes OD, Houle S, McKenzie K, Valmaggia LR, Bagby MR, Tseng HH, Bloomfield MA, Kenk M, Bhattacharyya S, Suridjan I, Chaddock CA, Winton-Brown TT, Allen P, Rusjan P, et al. Elevated Striatal Dopamine Function in Immigrants and Their Children: A Risk Mechanism for Psychosis. Schizophrenia Bulletin. PMID 28057720 DOI: 10.1093/Schbul/Sbw181 |
0.49 |
|
| 2017 |
Froudist-Walsh S, Bloomfield MA, Veronese M, Kroll J, Karolis VR, Jauhar S, Bonoldi I, McGuire PK, Kapur S, Murray RM, Nosarti C, Howes O. Author response: The effect of perinatal brain injury on dopaminergic function and hippocampal volume in adult life Elife. DOI: 10.7554/Elife.29088.012 |
0.741 |
|
| 2017 |
Egerton A, Merritt K, McQueen G, Howes O, Demjaha A, Brugger S, Barker G, Stone J, Dazzan P, Broberg B, van Haren N, Glenthoj B, Kahn R, McGuire P. SA83. Brain Glutamate Levels and Antipsychotic Response in Schizophrenia Schizophrenia Bulletin. 43: S142-S143. DOI: 10.1093/Schbul/Sbx023.081 |
0.522 |
|
| 2017 |
Rogdaki M, Gudbrandsen M, Daly E, Bonoldi I, Jauhar S, Donocik J, Veronese M, Turkheimer F, Howes O. 142. State or Trait? Investigation of Dopamine Function in Individuals With 22q11 Deletion Schizophrenia Bulletin. 43: S75-S75. DOI: 10.1093/Schbul/Sbx021.200 |
0.329 |
|
| 2017 |
Marques TR, Bloomfield P, Owen D, Gunn R, Rabiner E, Veronese M, Howes O. 117.4 Pet Imaging of Neuroinflammation in Schizophrenia Schizophrenia Bulletin. 43: S64-S65. DOI: 10.1093/Schbul/Sbx021.171 |
0.737 |
|
| 2017 |
Jauhar S, Veronese M, Rogdaki M, Turkheimer F, Reis-Marques T, Bonoldi I, Nour M, Borgan F, Pepper F, Egerton A, Stone J, McGuire P, Kapur S, Howes O. 74. The Neurochemical Basis of Antipsychotic Response in Psychosis: A Prospective Multimodal 18 F-Dopa and 1-H MRS Study in First-Episode Psychosis. Schizophrenia Bulletin. 43: S43-S43. DOI: 10.1093/Schbul/Sbx021.113 |
0.71 |
|
| 2017 |
Modinos G, Simsek F, Horder J, Bossong M, Samson C, Azis M, Quinn B, Bonoldi I, Howes O, Stone J, Allen P, McGuire P. 60.4 Multimodal Evidence of GABAergic Circuit Dysfunction in People at Clinical High Risk of Psychosis Schizophrenia Bulletin. 43: S35-S35. DOI: 10.1093/Schbul/Sbx021.091 |
0.449 |
|
| 2017 |
McGuire P, Allen P, Howes O, Bonoldi I, Grace A, Simsek F, Horder J, Stone J, Modinos G, Fusar-Poli P. 3.4 GABA Interneuron Dysfunction and the Onset of Psychosis Schizophrenia Bulletin. 43: S3-S4. DOI: 10.1093/Schbul/Sbx021.010 |
0.534 |
|
| 2017 |
Howes O. 3. Entraining Neural Networks Through Parvalbumin-Positive Interneurons: Can This Offer a Better way to Treat Schizophrenia? Schizophrenia Bulletin. 43: S2-S2. DOI: 10.1093/Schbul/Sbx021.006 |
0.352 |
|
| 2017 |
Ashok AH, Marques T, Rabiner E, Howes O. Mu-opioid receptor availability in schizophrenia patients: a PET study using [11C]-carfentanil European Neuropsychopharmacology. 27. DOI: 10.1016/S0924-977X(17)31615-2 |
0.796 |
|
| 2017 |
Howes O, Rogdaki M, Bloomfield M. 731. Biomarkers of Genetic and Environmental Psychosis Risk: Dopamine and Glutamate Imaging Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.798 |
0.361 |
|
| 2017 |
Howes O, Kokkinou M. 79. The Effects of Repeated NMDA Blockade with Ketamine on Dopamine and Glutamate Function Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.091 |
0.336 |
|
| 2016 |
Baumeister D, Sedgwick O, Howes O, Peters E. Auditory verbal hallucinations and continuum models of psychosis: A systematic review of the healthy voice-hearer literature. Clinical Psychology Review. 51: 125-141. PMID 27866082 DOI: 10.1016/J.Cpr.2016.10.010 |
0.305 |
|
| 2016 |
Kim E, Howes OD, Veronese M, Beck K, Seo S, Park JW, Lee JS, Lee YS, Kwon JS. Presynaptic Dopamine Capacity in Patients with Treatment Resistant Schizophrenia Taking Clozapine: An [(18)F]DOPA PET Study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27857125 DOI: 10.1038/npp.2016.258 |
0.314 |
|
| 2016 |
Bloomfield MA, Ashok AH, Volkow ND, Howes OD. The effects of Δ(9)-tetrahydrocannabinol on the dopamine system. Nature. 539: 369-377. PMID 27853201 DOI: 10.1038/Nature20153 |
0.702 |
|
| 2016 |
Howes OD, McCutcheon R, Owen MJ, Murray RM. The Role of Genes, Stress, and Dopamine in the Development of Schizophrenia. Biological Psychiatry. PMID 27720198 DOI: 10.1016/J.Biopsych.2016.07.014 |
0.368 |
|
| 2016 |
Egerton A, Valmaggia LR, Howes OD, Day F, Chaddock CA, Allen P, Winton-Brown TT, Bloomfield MA, Bhattacharyya S, Chilcott J, Lappin JM, Murray RM, McGuire P. Adversity in childhood linked to elevated striatal dopamine function in adulthood. Schizophrenia Research. PMID 27344984 DOI: 10.1016/J.Schres.2016.06.005 |
0.456 |
|
| 2016 |
Valli I, Crossley NA, Day F, Stone J, Tognin S, Mondelli V, Howes O, Valmaggia L, Pariante C, McGuire P. HPA-axis function and grey matter volume reductions: imaging the diathesis-stress model in individuals at ultra-high risk of psychosis. Translational Psychiatry. 6: e797. PMID 27138796 DOI: 10.1038/Tp.2016.68 |
0.47 |
|
| 2016 |
Madeira L, Bonoldi I, Rocchetti M, Brandizzi M, Samson C, Azis M, Queen B, Bossong M, Allen P, Perez J, Howes OD, McGuire P, Fusar-Poli P. Prevalence and implications of Truman symptoms in subjects at ultra high risk for psychosis. Psychiatry Research. 238: 270-6. PMID 27086244 DOI: 10.1016/J.Psychres.2016.02.001 |
0.349 |
|
| 2016 |
Madeira L, Bonoldi I, Rocchetti M, Samson C, Azis M, Queen B, Bossong M, Perez J, Stone J, Allen P, Howes OD, McGuire P, Raballo A, Fusar-Poli P, Ballerini M, et al. An initial investigation of abnormal bodily phenomena in subjects at ultra high risk for psychosis: Their prevalence and clinical implications. Comprehensive Psychiatry. 66: 39-45. PMID 26995234 DOI: 10.1016/J.Comppsych.2015.12.005 |
0.396 |
|
| 2016 |
Marques TR, Natesan S, Niccolini F, Politis M, Gunn RN, Searle GE, Howes O, Rabiner EA, Kapur S. Phosphodiesterase 10A in Schizophrenia: A PET Study Using [(11)C]IMA107. The American Journal of Psychiatry. appiajp201515040518. PMID 26892941 DOI: 10.1176/Appi.Ajp.2015.15040518 |
0.429 |
|
| 2016 |
Howes OD, Nour MM. Dopamine and the aberrant salience hypothesis of schizophrenia. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 15: 3-4. PMID 26833595 DOI: 10.1002/wps.20276 |
0.704 |
|
| 2016 |
Gee S, Howes O. Optimising treatment of schizophrenia: the role of adjunctive fluvoxamine. Psychopharmacology. PMID 26780617 DOI: 10.1007/S00213-016-4207-Z |
0.39 |
|
| 2016 |
Pollak TA, Beck K, Irani SR, Howes OD, David AS, McGuire PK. Autoantibodies to central nervous system neuronal surface antigens: psychiatric symptoms and psychopharmacological implications. Psychopharmacology. 233: 1605-21. PMID 26667479 DOI: 10.1007/S00213-015-4156-Y |
0.459 |
|
| 2016 |
Jauhar S, Veronese M, Hathway P, Rogdaki M, Egerton A, Stone J, Turkheimer F, McGuire P, Kapur S, Howes O. Determinants of treatment response in first episode psychosis: a prospective 18F-DOPA PET study European Neuropsychopharmacology. 26. DOI: 10.1016/S0924-977X(16)31662-5 |
0.325 |
|
| 2016 |
Bloomfield M, Howes O, Ashok A, Volkow N. Neuropsychopharmacology in human cannabis users: findings from molecular imaging European Neuropsychopharmacology. 26. DOI: 10.1016/S0924-977X(16)30878-1 |
0.663 |
|
| 2015 |
Allen P, Chaddock CA, Egerton A, Howes OD, Bonoldi I, Zelaya F, Bhattacharyya S, Murray R, McGuire P. Resting Hyperperfusion of the Hippocampus, Midbrain, and Basal Ganglia in People at High Risk for Psychosis. The American Journal of Psychiatry. appiajp201515040485. PMID 26684922 DOI: 10.1176/Appi.Ajp.2015.15040485 |
0.386 |
|
| 2015 |
Froudist-Walsh S, Karolis V, Caldinelli C, Brittain PJ, Kroll J, Rodríguez-Toscano E, Tesse M, Colquhoun M, Howes O, Dell'Acqua F, Thiebaut de Schotten M, Murray RM, Williams SC, Nosarti C. Very Early Brain Damage Leads to Remodeling of the Working Memory System in Adulthood: A Combined fMRI/Tractography Study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15787-99. PMID 26631462 DOI: 10.1523/Jneurosci.4769-14.2015 |
0.741 |
|
| 2015 |
Rogdaki M, Jauhar S, McCutcheon R, Howes O. Treatment-Resistant Schizophrenia in a Patient With 17q12 Duplication. Biological Psychiatry. PMID 26582588 DOI: 10.1016/J.Biopsych.2015.10.001 |
0.347 |
|
| 2015 |
Turkheimer FE, Rizzo G, Bloomfield PS, Howes O, Zanotti-Fregonara P, Bertoldo A, Veronese M. The methodology of TSPO imaging with positron emission tomography. Biochemical Society Transactions. 43: 586-92. PMID 26551697 DOI: 10.1042/Bst20150058 |
0.326 |
|
| 2015 |
Bloomfield PS, Selvaraj S, Veronese M, Rizzo G, Bertoldo A, Owen DR, Bloomfield MA, Bonoldi I, Kalk N, Turkheimer F, McGuire P, de Paola V, Howes OD. Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [(11)C]PBR28 PET Brain Imaging Study. The American Journal of Psychiatry. appiajp201514101358. PMID 26472628 DOI: 10.1176/appi.ajp.2015.14101358 |
0.734 |
|
| 2015 |
Valmaggia LR, Byrne M, Day F, Broome MR, Johns L, Howes O, Power P, Badger S, Fusar-Poli P, McGuire PK. Duration of untreated psychosis and need for admission in patients who engage with mental health services in the prodromal phase. The British Journal of Psychiatry : the Journal of Mental Science. PMID 26045348 DOI: 10.1192/Bjp.Bp.114.150623 |
0.392 |
|
| 2015 |
Nour MM, Howes OD. Interpreting the neurodevelopmental hypothesis of schizophrenia in the context of normal brain development and ageing. Proceedings of the National Academy of Sciences of the United States of America. 112: E2745. PMID 25941415 DOI: 10.1073/pnas.1502170112 |
0.66 |
|
| 2015 |
Bossong MG, Mehta MA, van Berckel BN, Howes OD, Kahn RS, Stokes PR. Further human evidence for striatal dopamine release induced by administration of ∆9-tetrahydrocannabinol (THC): selectivity to limbic striatum. Psychopharmacology. 232: 2723-9. PMID 25801289 DOI: 10.1007/S00213-015-3915-0 |
0.355 |
|
| 2015 |
Howes O, McCutcheon R, Stone J. Glutamate and dopamine in schizophrenia: an update for the 21st century. Journal of Psychopharmacology (Oxford, England). 29: 97-115. PMID 25586400 DOI: 10.1177/0269881114563634 |
0.476 |
|
| 2015 |
Shaikh M, Dutt A, Broome MR, Vozmediano AG, Ranlund S, Diez A, Caseiro O, Lappin J, Amankwa S, Carletti F, Fusar-Poli P, Walshe M, Hall MH, Howes O, Ellett L, et al. Sensory gating deficits in the attenuated psychosis syndrome. Schizophrenia Research. 161: 277-82. PMID 25556079 DOI: 10.1016/J.Schres.2014.12.021 |
0.454 |
|
| 2015 |
Winton-Brown TT, Broome MR, Allen P, Valli I, Howes O, Garety PA, Johns LC, McGuire P. Misattributing speech and jumping to conclusions: a longitudinal study in people at high risk of psychosis. European Psychiatry : the Journal of the Association of European Psychiatrists. 30: 32-7. PMID 25511317 DOI: 10.1016/J.Eurpsy.2014.09.416 |
0.457 |
|
| 2015 |
Bloomfield MA, Jauhar S, Froudist-Walsh S, Bonoldi I, Howes OD. Commentary on a study of the prevalence of mental disorders by Breslau et al. Journal of Psychiatric Research. 61: 231-2. PMID 25499560 DOI: 10.1016/J.Jpsychires.2014.11.006 |
0.617 |
|
| 2015 |
Allen P, Chaddock CA, Egerton A, Howes OD, Barker G, Bonoldi I, Fusar-Poli P, Murray R, McGuire P. Functional outcome in people at high risk for psychosis predicted by thalamic glutamate levels and prefronto-striatal activation. Schizophrenia Bulletin. 41: 429-39. PMID 25123110 DOI: 10.1093/Schbul/Sbu115 |
0.385 |
|
| 2015 |
Pollak TA, Beck K, Irani SR, Howes OD, David AS, McGuire PK. Autoantibodies to central nervous system neuronal surface antigens: psychiatric symptoms and psychopharmacological implications Psychopharmacology. 1-17. DOI: 10.1007/s00213-015-4156-y |
0.306 |
|
| 2014 |
Valmaggia LR, Day FL, Jones C, Bissoli S, Pugh C, Hall D, Bhattacharyya S, Howes O, Stone J, Fusar-Poli P, Byrne M, McGuire PK. Cannabis use and transition to psychosis in people at ultra-high risk. Psychological Medicine. 44: 2503-12. PMID 25055169 DOI: 10.1017/S0033291714000117 |
0.437 |
|
| 2014 |
Kambeitz J, Abi-Dargham A, Kapur S, Howes OD. Alterations in cortical and extrastriatal subcortical dopamine function in schizophrenia: systematic review and meta-analysis of imaging studies. The British Journal of Psychiatry : the Journal of Mental Science. 204: 420-9. PMID 25029687 DOI: 10.1055/S-0033-1353335 |
0.455 |
|
| 2014 |
Selvaraj S, Arnone D, Cappai A, Howes O. Alterations in the serotonin system in schizophrenia: a systematic review and meta-analysis of postmortem and molecular imaging studies. Neuroscience and Biobehavioral Reviews. 45: 233-45. PMID 24971825 DOI: 10.1016/J.Neubiorev.2014.06.005 |
0.389 |
|
| 2014 |
Bonoldi I, Howes OD. Presynaptic dopaminergic function: implications for understanding treatment response in psychosis. Cns Drugs. 28: 649-63. PMID 24919790 DOI: 10.1007/s40263-014-0177-z |
0.345 |
|
| 2014 |
Egerton A, Stone JM, Chaddock CA, Barker GJ, Bonoldi I, Howard RM, Merritt K, Allen P, Howes OD, Murray RM, McLean MA, Lythgoe DJ, O'Gorman RL, McGuire PK. Relationship between brain glutamate levels and clinical outcome in individuals at ultra high risk of psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2891-9. PMID 24917199 DOI: 10.1038/Npp.2014.143 |
0.414 |
|
| 2014 |
Selvaraj S, Mouchlianitis E, Faulkner P, Turkheimer F, Cowen PJ, Roiser JP, Howes O. Presynaptic Serotoninergic Regulation of Emotional Processing: A Multimodal Brain Imaging Study. Biological Psychiatry. PMID 24882568 DOI: 10.1016/J.Biopsych.2014.04.011 |
0.555 |
|
| 2014 |
Bloomfield MA, Pepper F, Egerton A, Demjaha A, Tomasi G, Mouchlianitis E, Maximen L, Veronese M, Turkheimer F, Selvaraj S, Howes OD. Dopamine function in cigarette smokers: an [¹â¸F]-DOPA PET study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2397-404. PMID 24718373 DOI: 10.1038/Npp.2014.87 |
0.343 |
|
| 2014 |
Selvaraj S, Turkheimer F, Howes O. Dopamine transporter imaging: nonindependence of regional measures. Molecular Psychiatry. 19: 964. PMID 24589891 DOI: 10.1038/Mp.2014.15 |
0.37 |
|
| 2014 |
Faulkner P, Selvaraj S, Pine A, Howes OD, Roiser JP. The relationship between reward and punishment processing and the 5-HT1A receptor as shown by PET. Psychopharmacology. 231: 2579-86. PMID 24429872 DOI: 10.1007/s00213-013-3426-9 |
0.507 |
|
| 2014 |
Goghari VM, Brett C, Tabraham P, Johns L, Valmaggia L, Broome M, Woolley J, Bramon E, Howes O, Byrne M, McGuire P. Spatial working memory ability in individuals at ultra high risk for psychosis. Journal of Psychiatric Research. 50: 100-5. PMID 24398256 DOI: 10.1016/J.Jpsychires.2013.12.010 |
0.421 |
|
| 2014 |
Winton-Brown TT, Fusar-Poli P, Ungless MA, Howes OD. Dopaminergic basis of salience dysregulation in psychosis. Trends in Neurosciences. 37: 85-94. PMID 24388426 DOI: 10.1016/J.Tins.2013.11.003 |
0.32 |
|
| 2014 |
Williams MR, Galvin K, O'Sullivan B, MacDonald CD, Ching EW, Turkheimer F, Howes OD, Pearce RK, Hirsch SR, Maier M. Neuropathological changes in the substantia nigra in schizophrenia but not depression. European Archives of Psychiatry and Clinical Neuroscience. 264: 285-96. PMID 24374935 DOI: 10.1007/S00406-013-0479-Z |
0.456 |
|
| 2014 |
Mondelli V, Howes O. Inflammation: its role in schizophrenia and the potential anti-inflammatory effects of antipsychotics. Psychopharmacology. 231: 317-8. PMID 24337065 DOI: 10.1007/S00213-013-3383-3 |
0.36 |
|
| 2014 |
Howes OD, Murray RM. Schizophrenia: an integrated sociodevelopmental-cognitive model. Lancet. 383: 1677-87. PMID 24315522 DOI: 10.1016/S0140-6736(13)62036-X |
0.315 |
|
| 2014 |
Stokes PR, Benecke A, Puraite J, Bloomfield MA, Shotbolt P, Reeves SJ, Lingford-Hughes AR, Howes O, Egerton A. Does human presynaptic striatal dopamine function predict social conformity? Journal of Psychopharmacology (Oxford, England). 28: 237-43. PMID 24257812 DOI: 10.1177/0269881113512037 |
0.382 |
|
| 2014 |
Gee S, Vergunst F, Howes O, Taylor D. Practitioner attitudes to clozapine initiation. Acta Psychiatrica Scandinavica. 130: 16-24. PMID 24004162 DOI: 10.1111/Acps.12193 |
0.393 |
|
| 2014 |
Demjaha A, Egerton A, Murray RM, Kapur S, Howes OD, Stone JM, McGuire PK. Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function. Biological Psychiatry. 75: e11-3. PMID 23890739 DOI: 10.1016/j.biopsych.2013.06.011 |
0.487 |
|
| 2014 |
Bloomfield MA, Morgan CJ, Egerton A, Kapur S, Curran HV, Howes OD. Dopaminergic function in cannabis users and its relationship to cannabis-induced psychotic symptoms. Biological Psychiatry. 75: 470-8. PMID 23820822 DOI: 10.1016/j.biopsych.2013.05.027 |
0.313 |
|
| 2014 |
Koychev I, Winton-Brown T, Egerton A, Howes O, Mullins P, Kapur S, Mathews P, McGuire P, Stone J. P.3.b.007 Altered dorsolateral prefrontal cortex glutamate and striatal dopamine relationship in subjects at ultra high risk of psychosis European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70791-6 |
0.375 |
|
| 2014 |
Bossong MG, Allen P, Samson C, Rasheed H, Quinn B, Bonoldi I, Modinos G, Stone J, Howes O, McGuire P. Poster #T27 ALTERED HIPPOCAMPAL GLUTAMATE FUNCTION IN PEOPLE AT ULTRA HIGH RISK FOR PSYCHOSIS Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70844-8 |
0.437 |
|
| 2014 |
Demjaha A, Lappin J, Patel MX, MacCabe JH, Morgan K, Reininghaus U, Howes O, Jones PB, Murray RM, Morgan C, Dazzan P. 5:15 Pm Is Treatment Resistant Schizophrenia A “Type” Or A “Stage” Of Psychotic Illness? Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70205-1 |
0.366 |
|
| 2014 |
Allen P, Chaddock C, Egerton A, Howes O, Zelaya F, McGuire P. 4:15 Pm Altered Relationship Between Medial Temporal Lobe Resting Cerebral Blood Flow And Striatal Dopamine Synthesis Capacity In People At Risk Of Psychosis Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70201-4 |
0.487 |
|
| 2014 |
Mouchlianitis E, Bloomfield M, Law V, Beck K, Demjaha A, Stone J, Howes O. 4:45 Pm Elevated Anterior Cingulate Cortex Glutamate Levels Are Associated With Antipsychotic Treatment Resistance And Clinical Severity In Schizophrenia Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70177-X |
0.383 |
|
| 2014 |
Allen P, Chaddock C, Egerton A, Howes O, Stone J, Barker G, Bonoldi I, McGuire P. 5:00 Pm Functional Outcome In People At High Risk For Psychosis Predicted By Thalamic Glutamate Levels And Prefronto-Striatal Activation Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70169-0 |
0.448 |
|
| 2014 |
Howes O, Egerton A, Allen P, Chaddock C, McGuire P. Is The Associative Striatum A Locus Of Vulnerability For Transition To Psychosis Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70113-6 |
0.425 |
|
| 2014 |
Howes O, Allen P, Chaddock C, Egerton A, Valli I, McGuire P. Outcome In Subjects At Ultra High Risk Of Psychosis: Relationship To Dopaminergic Function Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70057-X |
0.443 |
|
| 2013 |
Howes OD, Williams M, Ibrahim K, Leung G, Egerton A, McGuire PK, Turkheimer F. Midbrain dopamine function in schizophrenia and depression: a post-mortem and positron emission tomographic imaging study. Brain : a Journal of Neurology. 136: 3242-51. PMID 24097339 DOI: 10.1093/brain/awt264 |
0.524 |
|
| 2013 |
Bonoldi I, Howes OD. The enduring centrality of dopamine in the pathophysiology of schizophrenia: in vivo evidence from the prodrome to the first psychotic episode. Advances in Pharmacology (San Diego, Calif.). 68: 199-220. PMID 24054146 DOI: 10.1016/B978-0-12-411512-5.00010-5 |
0.49 |
|
| 2013 |
Tseng HH, Chen SH, Liu CM, Howes O, Huang YL, Hsieh MH, Liu CC, Shan JC, Lin YT, Hwu HG. Facial and prosodic emotion recognition deficits associate with specific clusters of psychotic symptoms in schizophrenia. Plos One. 8: e66571. PMID 23818944 DOI: 10.1371/Journal.Pone.0066571 |
0.342 |
|
| 2013 |
Beck K, Howes O. Optimising treatment of refractory schizophrenia. Psychopharmacology. 227: 373-4. PMID 23568576 DOI: 10.1007/S00213-013-3076-Y |
0.389 |
|
| 2013 |
Egerton A, Chaddock CA, Winton-Brown TT, Bloomfield MA, Bhattacharyya S, Allen P, McGuire PK, Howes OD. Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: findings in a second cohort. Biological Psychiatry. 74: 106-12. PMID 23312565 DOI: 10.1016/j.biopsych.2012.11.017 |
0.46 |
|
| 2013 |
Roiser JP, Howes OD, Chaddock CA, Joyce EM, McGuire P. Neural and behavioral correlates of aberrant salience in individuals at risk for psychosis. Schizophrenia Bulletin. 39: 1328-36. PMID 23236077 DOI: 10.1093/Schbul/Sbs147 |
0.465 |
|
| 2013 |
Stokes PR, Shotbolt P, Mehta MA, Turkheimer E, Benecke A, Copeland C, Turkheimer FE, Lingford-Hughes AR, Howes OD. Nature or nurture? Determining the heritability of human striatal dopamine function: an [18F]-DOPA PET study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 485-91. PMID 23093224 DOI: 10.1038/Npp.2012.207 |
0.662 |
|
| 2013 |
Mendez MA, Horder J, Myers J, Coghlan S, Stokes P, Erritzoe D, Howes O, Lingford-Hughes A, Murphy D, Nutt D. The brain GABA-benzodiazepine receptor alpha-5 subtype in autism spectrum disorder: a pilot [(11)C]Ro15-4513 positron emission tomography study. Neuropharmacology. 68: 195-201. PMID 22546616 DOI: 10.1016/J.Neuropharm.2012.04.008 |
0.314 |
|
| 2013 |
Howes OD, Shotbolt P, Bloomfield M, Daalman K, Demjaha A, Diederen KM, Ibrahim K, Kim E, McGuire P, Kahn RS, Sommer IE. Dopaminergic function in the psychosis spectrum: an [18F]-DOPA imaging study in healthy individuals with auditory hallucinations. Schizophrenia Bulletin. 39: 807-14. PMID 22282457 DOI: 10.1093/Schbul/Sbr195 |
0.487 |
|
| 2013 |
Chen KC, Yang YK, Howes O, Lee IH, Landau S, Yeh TL, Chiu NT, Chen PS, Lu RB, David AS, Bramon E. Striatal dopamine transporter availability in drug-naive patients with schizophrenia: a case-control SPECT study with [(99m)Tc]-TRODAT-1 and a meta-analysis. Schizophrenia Bulletin. 39: 378-86. PMID 22156764 DOI: 10.1093/Schbul/Sbr163 |
0.449 |
|
| 2012 |
Lord LD, Allen P, Expert P, Howes O, Broome M, Lambiotte R, Fusar-Poli P, Valli I, McGuire P, Turkheimer FE. Functional brain networks before the onset of psychosis: A prospective fMRI study with graph theoretical analysis. Neuroimage. Clinical. 1: 91-8. PMID 24179741 DOI: 10.1016/J.Nicl.2012.09.008 |
0.471 |
|
| 2012 |
Selvaraj S, Faulkner P, Mouchlianitis E, Roiser JP, Howes O. Effects of citalopram on serotonin neurotransmission. Molecular Psychiatry. 17: 1143. PMID 23168914 DOI: 10.1038/Mp.2012.166 |
0.553 |
|
| 2012 |
Demjaha A, Murray RM, McGuire PK, Kapur S, Howes OD. Dopamine synthesis capacity in patients with treatment-resistant schizophrenia. The American Journal of Psychiatry. 169: 1203-10. PMID 23034655 DOI: 10.1176/appi.ajp.2012.12010144 |
0.53 |
|
| 2012 |
Howes OD, Vergunst F, Gee S, McGuire P, Kapur S, Taylor D. Adherence to treatment guidelines in clinical practice: study of antipsychotic treatment prior to clozapine initiation. The British Journal of Psychiatry : the Journal of Mental Science. 201: 481-5. PMID 22955007 DOI: 10.1192/Bjp.Bp.111.105833 |
0.409 |
|
| 2012 |
Marques TR, Smith S, Bonaccorso S, Gaughran F, Kolliakou A, Dazzan P, Mondelli V, Taylor H, Diforti M, McGuire PK, Murray RM, Howes OD. Sexual dysfunction in people with prodromal or first-episode psychosis. The British Journal of Psychiatry : the Journal of Mental Science. 201: 131-6. PMID 22700081 DOI: 10.1192/bjp.bp.111.101220 |
0.322 |
|
| 2012 |
Selvaraj S, Turkheimer F, Rosso L, Faulkner P, Mouchlianitis E, Roiser JP, McGuire P, Cowen PJ, Howes O. Measuring endogenous changes in serotonergic neurotransmission in humans: a [11C]CUMI-101 PET challenge study. Molecular Psychiatry. 17: 1254-60. PMID 22665264 DOI: 10.1038/Mp.2012.78 |
0.627 |
|
| 2012 |
Fusar-Poli P, Deste G, Smieskova R, Barlati S, Yung AR, Howes O, Stieglitz RD, Vita A, McGuire P, Borgwardt S. Cognitive functioning in prodromal psychosis: a meta-analysis. Archives of General Psychiatry. 69: 562-71. PMID 22664547 DOI: 10.1001/Archgenpsychiatry.2011.1592 |
0.434 |
|
| 2012 |
Howes OD, Kambeitz J, Kim E, Stahl D, Slifstein M, Abi-Dargham A, Kapur S. The nature of dopamine dysfunction in schizophrenia and what this means for treatment. Archives of General Psychiatry. 69: 776-86. PMID 22474070 DOI: 10.1055/S-0033-1353348 |
0.439 |
|
| 2012 |
Fusar-Poli P, Howes O, Bechdolf A, Borgwardt S. Mapping vulnerability to bipolar disorder: a systematic review and meta-analysis of neuroimaging studies. Journal of Psychiatry & Neuroscience : Jpn. 37: 170-84. PMID 22297067 DOI: 10.1503/Jpn.110061 |
0.331 |
|
| 2012 |
Allen P, Luigjes J, Howes OD, Egerton A, Hirao K, Valli I, Kambeitz J, Fusar-Poli P, Broome M, McGuire P. Transition to psychosis associated with prefrontal and subcortical dysfunction in ultra high-risk individuals. Schizophrenia Bulletin. 38: 1268-76. PMID 22290265 DOI: 10.1093/Schbul/Sbr194 |
0.438 |
|
| 2012 |
Valmaggia LR, McGuire PK, Fusar-Poli P, Howes O, McCrone P. Economic impact of early detection and early intervention of psychosis. Current Pharmaceutical Design. 18: 592-5. PMID 22239592 DOI: 10.2174/138161212799316145 |
0.389 |
|
| 2012 |
Howes OD, Fusar-Poli P, Bloomfield M, Selvaraj S, McGuire P. From the prodrome to chronic schizophrenia: the neurobiology underlying psychotic symptoms and cognitive impairments. Current Pharmaceutical Design. 18: 459-65. PMID 22239576 DOI: 10.2174/138161212799316217 |
0.548 |
|
| 2012 |
Masillo A, Day F, Laing J, Howes O, Fusar-Poli P, Byrne M, Bhattacharyya S, Fiori Nastro P, Girardi P, McGuire PK, Valmaggia LR. Interpersonal sensitivity in the at-risk mental state for psychosis. Psychological Medicine. 42: 1835-45. PMID 22225783 DOI: 10.1017/S0033291711002996 |
0.441 |
|
| 2012 |
Shaikh M, Valmaggia L, Broome MR, Dutt A, Lappin J, Day F, Woolley J, Tabraham P, Walshe M, Johns L, Fusar-Poli P, Howes O, Murray RM, McGuire P, Bramon E. Reduced mismatch negativity predates the onset of psychosis. Schizophrenia Research. 134: 42-8. PMID 22024244 DOI: 10.1016/J.Schres.2011.09.022 |
0.463 |
|
| 2012 |
Allen P, Chaddock CA, Howes OD, Egerton A, Seal ML, Fusar-Poli P, Valli I, Day F, McGuire PK. Abnormal relationship between medial temporal lobe and subcortical dopamine function in people with an ultra high risk for psychosis. Schizophrenia Bulletin. 38: 1040-9. PMID 21536784 DOI: 10.1093/Schbul/Sbr017 |
0.487 |
|
| 2012 |
Selvaraj S, Faulkner P, Mouchlianitis E, Turkheimer F, Rosso L, Cowen PJ, Roiser JP, Howes O. Detecting endogenous changes in serotonergic neurotransmission in humans: a [ 11 C]CUMI-101 PET challenge study F1000research. 3. DOI: 10.7490/F1000Research.1090241.1 |
0.565 |
|
| 2012 |
Selvaraj S, Turkheimer F, Faulkner P, Mouchlianitis E, Roiser JP, McGuire P, Cowen PJ, Howes O. P.1.e.004 Brain serotonin neurotransmission and affect regulation in humans: a positron emission tomography study European Neuropsychopharmacology. 22. DOI: 10.1016/S0924-977X(12)70279-1 |
0.611 |
|
| 2012 |
Selvaraj S, Faulkner P, Mouchlianitis E, Turkheimer F, Rosso L, Roiser J, Cowen P, Howes O. P-800 - How do antidepressants work? A Positron Emission Tomography (PET) study of brain serotonin levels and affect regulation European Psychiatry. 27: 1. DOI: 10.1016/S0924-9338(12)74967-2 |
0.58 |
|
| 2012 |
Demjaha A, Murray R, Kapur S, Howes O. Poster #126 DOPAMINERGIC FUNCTION IN TREATMENT RESISTANT SCHIZOPHRENIA: NEW EVIDENCE FROM AN [18]-DOPA PET STUDY Schizophrenia Research. 136. DOI: 10.1016/S0920-9964(12)70440-1 |
0.426 |
|
| 2012 |
Chaddock CA, Roiser lP, Howes OD, McGuire PK. 14:00 ABERRANT PREDICTION ERROR SIGNALLING, SALIENCE ATTRIBUTION AND PRESYNAPTIC DOPAMINE SYNTHESIS IN THE PRODROME OF PSYCHOSIS Schizophrenia Research. 136: S81. DOI: 10.1016/S0920-9964(12)70291-8 |
0.38 |
|
| 2012 |
Howes OD, Bloomfield M, Bhattacharyya S, Stokes P, McGuire P. THE LINK BETWEEN CANNABIS AND SCHIZOPHRENIA: DOPAMINERGIC OR CANNABINOID SYSTEM? Schizophrenia Research. 136: S68. DOI: 10.1016/S0920-9964(12)70255-4 |
0.477 |
|
| 2012 |
McGuire P, Howes O, Stone J, Egerton A, Tognin S, Fusar-Poli P, Borgwardt S, Allen P, Valli I, Barker G, Roiser J, Chaddock C, Mechelli A. ALTERATIONS IN BRAIN STRUCTURE, FUNCTION AND CHEMISTRY PRIOR TO THE ONSET OF PSYCHOSIS Schizophrenia Research. 136: S55. DOI: 10.1016/S0920-9964(12)70200-1 |
0.449 |
|
| 2011 |
McGuire P, Selvaraj S, Howes O. Is clinical intervention in the ultra high risk phase effective? Revista Brasileira De Psiquiatria (Sã£O Paulo, Brazil : 1999). 33: s161-74. PMID 22286566 DOI: 10.1590/S1516-44462011000600004 |
0.467 |
|
| 2011 |
Howes OD, Bose SK, Turkheimer F, Valli I, Egerton A, Valmaggia LR, Murray RM, McGuire P. Dopamine synthesis capacity before onset of psychosis: a prospective [18F]-DOPA PET imaging study. The American Journal of Psychiatry. 168: 1311-7. PMID 21768612 DOI: 10.1176/Appi.Ajp.2011.11010160 |
0.554 |
|
| 2011 |
Shotbolt P, Stokes PR, Owens SF, Toulopoulou T, Picchioni MM, Bose SK, Murray RM, Howes OD. Striatal dopamine synthesis capacity in twins discordant for schizophrenia. Psychological Medicine. 41: 2331-8. PMID 21426628 DOI: 10.1017/S0033291711000341 |
0.471 |
|
| 2011 |
Howes O, Bose S, Turkheimer F, Valli I, Egerton A, Stahl D, Valmaggia L, Allen P, Murray R, McGuire P. Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study. Molecular Psychiatry. 16: 885-6. PMID 21358709 DOI: 10.1038/Mp.2011.20 |
0.527 |
|
| 2011 |
Lord LD, Allen P, Expert P, Howes O, Lambiotte R, McGuire P, Bose SK, Hyde S, Turkheimer FE. Characterization of the anterior cingulate's role in the at-risk mental state using graph theory. Neuroimage. 56: 1531-9. PMID 21316462 DOI: 10.1016/J.Neuroimage.2011.02.012 |
0.427 |
|
| 2011 |
Howes OD, Lim S, Theologos G, Yung AR, Goodwin GM, McGuire P. A comprehensive review and model of putative prodromal features of bipolar affective disorder. Psychological Medicine. 41: 1567-77. PMID 20836910 DOI: 10.1017/S0033291710001790 |
0.314 |
|
| 2011 |
Fusar-Poli P, Howes OD, Allen P, Broome M, Valli I, Asselin MC, Montgomery AJ, Grasby PM, McGuire P. Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis. Molecular Psychiatry. 16: 67-75. PMID 19949389 DOI: 10.1038/Mp.2009.108 |
0.496 |
|
| 2011 |
Stone JM, Howes OD, Egerton A, Kambeitz J, Allen P, Lythgoe DJ, O'Gorman RL, McLean MA, Barker GJ, McGuire P. Reply to: Hippocampal glutamate levels and striatal dopamine D 2/3 receptor occupancy in subjects at ultra high risk of psychosis Biological Psychiatry. 70: e3-e4. DOI: 10.1016/J.Biopsych.2011.01.039 |
0.427 |
|
| 2010 |
Stone JM, Howes OD, Egerton A, Kambeitz J, Allen P, Lythgoe DJ, O'Gorman RL, McLean MA, Barker GJ, McGuire P. Altered relationship between hippocampal glutamate levels and striatal dopamine function in subjects at ultra high risk of psychosis. Biological Psychiatry. 68: 599-602. PMID 20638047 DOI: 10.1016/J.Biopsych.2010.05.034 |
0.45 |
|
| 2010 |
Fusar-Poli P, Howes OD, Allen P, Broome M, Valli I, Asselin MC, Grasby PM, McGuire PK. Abnormal frontostriatal interactions in people with prodromal signs of psychosis: a multimodal imaging study. Archives of General Psychiatry. 67: 683-91. PMID 20603449 DOI: 10.1001/Archgenpsychiatry.2010.77 |
0.482 |
|
| 2010 |
Egerton A, Demjaha A, McGuire P, Mehta MA, Howes OD. The test-retest reliability of 18F-DOPA PET in assessing striatal and extrastriatal presynaptic dopaminergic function. Neuroimage. 50: 524-31. PMID 20034580 DOI: 10.1016/j.neuroimage.2009.12.058 |
0.395 |
|
| 2010 |
Johns LC, Allen P, Valli I, Winton-Brown T, Broome M, Woolley J, Tabraham P, Day F, Howes O, Wykes T, McGuire P. Impaired verbal self-monitoring in individuals at high risk of psychosis. Psychological Medicine. 40: 1433-42. PMID 19951449 DOI: 10.1017/S0033291709991991 |
0.415 |
|
| 2010 |
Shotbolt JP, Stokes P, Howes OD, Grasby PM. STRIATAL DOPAMINE FUNCTION IN DIZYGOTIC TWIN PAIRS DISCORDANT FOR SCHIZOPHRENIA Schizophrenia Research. 117: 470. DOI: 10.1016/j.schres.2010.02.884 |
0.355 |
|
| 2010 |
Allen P, Chaddock C, Howes OD, Fusar-Poli P, Egerton A, McGuire P. ALTERED ASSOCIATION BETWEEN HIPPOCAMPAL ACTIVATION DURING EPISODIC ENCODING AND STRIATAL DOPAMINE FUNCTION IN PEOPLE WITH PRODROMAL SYMPTOMS OF PSYCHOSIS Schizophrenia Research. 117: 231. DOI: 10.1016/J.Schres.2010.02.342 |
0.466 |
|
| 2010 |
Howes O. Dopamine Dysregulation: Pathophysiology Or Endophenotype? Schizophrenia Research. 117: 136-136. DOI: 10.1016/J.Schres.2010.02.103 |
0.386 |
|
| 2009 |
Howes OD, Egerton A, Allan V, McGuire P, Stokes P, Kapur S. Mechanisms underlying psychosis and antipsychotic treatment response in schizophrenia: insights from PET and SPECT imaging. Current Pharmaceutical Design. 15: 2550-9. PMID 19689327 DOI: 10.2174/138161209788957528 |
0.561 |
|
| 2009 |
Fusar-Poli P, Howes OD, McGuire P. Pseudohallucinations versus true hallucinations in prodromal psychosis: does it really matter? The Journal of Clinical Psychiatry. 70: 1056-7. PMID 19653984 DOI: 10.4088/Jcp.08L04848 |
0.382 |
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| 2009 |
Howes OD, Kapur S. The dopamine hypothesis of schizophrenia: version III--the final common pathway. Schizophrenia Bulletin. 35: 549-62. PMID 19325164 DOI: 10.1093/schbul/sbp006 |
0.376 |
|
| 2009 |
Egerton A, McGuire PK, Howes OD. Functionally defined regions may aid interpretation of striatal dopamine elevation in schizophrenia. Schizophrenia Research. 109: 200. PMID 19250801 DOI: 10.1016/j.schres.2009.02.004 |
0.508 |
|
| 2009 |
Howes OD, Montgomery AJ, Asselin MC, Murray RM, Valli I, Tabraham P, Bramon-Bosch E, Valmaggia L, Johns L, Broome M, McGuire PK, Grasby PM. Elevated striatal dopamine function linked to prodromal signs of schizophrenia. Archives of General Psychiatry. 66: 13-20. PMID 19124684 DOI: 10.1001/Archgenpsychiatry.2008.514 |
0.51 |
|
| 2009 |
Prata DP, Mechelli A, Fu CH, Picchioni M, Kane F, Kalidindi S, McDonald C, Howes O, Kravariti E, Demjaha A, Toulopoulou T, Diforti M, Murray RM, Collier DA, McGuire PK. Opposite effects of catechol-O-methyltransferase Val158Met on cortical function in healthy subjects and patients with schizophrenia. Biological Psychiatry. 65: 473-80. PMID 19054502 DOI: 10.1016/J.Biopsych.2008.09.027 |
0.526 |
|
| 2009 |
Fusar-Poli P, Howes O, Valli I, Allen P, Broome M, Grasby P, McGuire P. Multimodal functional imaging investigation before and after the onset of psychosis. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 579-81. PMID 18925982 DOI: 10.1017/S146114570800953X |
0.44 |
|
| 2009 |
Bose S, Mackinnon T, Mehta M, Turkheimer F, Howes O, Selvaraj S, Kempton M, Grasby P. Progressive White Matter Loss in Patients with Schizophrenia Neuroimage. 47. DOI: 10.1016/S1053-8119(09)71342-4 |
0.363 |
|
| 2009 |
Howes O, Fusar-Poli P, Allen P, Murray R, Grasby P, McGuire P. P.3.a.032 The relationship between striatal dopamine function and frontal cortical function in the aetiology of psychosis European Neuropsychopharmacology. 19. DOI: 10.1016/S0924-977X(09)70787-4 |
0.508 |
|
| 2009 |
Egerton A, Shotbolt J, Stokes P, Howes O, Grasby P. P.1.e.022 Effect of bupropion on extracellular dopamine levels in the striatum: a translational PET approach European Neuropsychopharmacology. 19: S313. DOI: 10.1016/S0924-977X(09)70467-5 |
0.363 |
|
| 2009 |
Egerton A, Demjaha A, Grasby P, McGuire P, Murray R, Howes O. P.1.e.023 Longitudinal assessment of presynaptic dopamine function in the striatum: a [18]F-DOPA PET test-retest study European Neuropsychopharmacology. 19: S313-S314. DOI: 10.1016/S0924-977X(09)70466-3 |
0.422 |
|
| 2008 |
Valli I, Howes O, Tyrer P, McGuire P, Grasby PM. Longitudinal PET imaging in a patient with schizophrenia did not show marked changes in dopaminergic function with relapse of psychosis. The American Journal of Psychiatry. 165: 1613-4. PMID 19047337 DOI: 10.1176/Appi.Ajp.2008.08071109 |
0.559 |
|
| 2008 |
Bose SK, Turkheimer FE, Howes OD, Mehta MA, Cunliffe R, Stokes PR, Grasby PM. Classification of schizophrenic patients and healthy controls using [18F] fluorodopa PET imaging. Schizophrenia Research. 106: 148-55. PMID 18849151 DOI: 10.1016/j.schres.2008.09.011 |
0.308 |
|
| 2008 |
Fusar-Poli P, Howes O, Valmaggia L, McGuire P. 'Truman' signs and vulnerability to psychosis. The British Journal of Psychiatry : the Journal of Mental Science. 193: 168. PMID 18670010 DOI: 10.1192/Bjp.193.2.168 |
0.52 |
|
| 2008 |
Bramon E, Shaikh M, Broome M, Lappin J, Bergé D, Day F, Woolley J, Tabraham P, Madre M, Johns L, Howes O, Valmaggia L, Pérez V, Sham P, Murray RM, et al. Abnormal P300 in people with high risk of developing psychosis. Neuroimage. 41: 553-60. PMID 18387827 DOI: 10.1016/j.neuroimage.2007.12.038 |
0.379 |
|
| 2008 |
McGuire P, Howes OD, Stone J, Fusar-Poli P. Functional neuroimaging in schizophrenia: diagnosis and drug discovery Trends in Pharmacological Sciences. 29: 91-98. PMID 18187211 DOI: 10.1016/J.Tips.2007.11.005 |
0.499 |
|
| 2008 |
Reis Marques T, Murray R, McGuire P, Shubulade S, Howes O. SEXUAL FUNCTIONING IN THE AT RISK MENTAL STATE AND FIRST EPISODE SCHIZOPHRENIA Schizophrenia Research. 102: 159-160. DOI: 10.1016/S0920-9964(08)70485-7 |
0.41 |
|
| 2008 |
Howes OD, Montgomery AJ, Valli I, Asselin M, Murray RM, Grasby PM, McGuire P. STRIATAL DOPAMINE DYSFUNCTION PREDATES THE ONSET OF SCHIZOPHRENIA AND IS LINKED TO PRODROMAL SYMPTOMS AND NEUROCOGNITIVE FUNCTION Schizophrenia Research. 102: 30. DOI: 10.1016/S0920-9964(08)70094-X |
0.506 |
|
| 2007 |
Howes OD, Weinstein S, Tabraham P, Valmaggia L, Broome M, McGuire P. Slang and schizophrenia British Medical Journal. 335: 1294. PMID 18156234 DOI: 10.1136/Bmj.39419.647118.25 |
0.404 |
|
| 2007 |
Howes OD, Montgomery AJ, Asselin MC, Murray RM, Grasby PM, McGuire PK. Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis. The British Journal of Psychiatry. Supplement. 51: s13-8. PMID 18055930 DOI: 10.1192/bjp.191.51.s13 |
0.468 |
|
| 2007 |
Howes O, Montgomery A, Valli I, Asselin M, Murray R, McGuire P, Grasby P. P.1.e.024 Elevated striatal dopaminergic function is related to ‘prodromal psychotic’ symptoms prior to the onset of schizophrenia European Neuropsychopharmacology. 17: S294-S295. DOI: 10.1016/S0924-977X(07)70414-5 |
0.416 |
|
| 2006 |
Howes O, Montgomery A, Asselin M, Murray R, Grasby P, McGuire P. S.07.07 The pre-synaptic dopaminergic system before and after the onset of psychosis: initial results European Neuropsychopharmacology. 16: S177. DOI: 10.1016/S0924-977X(06)70050-5 |
0.352 |
|
| 2006 |
Allen P, Johns L, Broome M, Woolley J, Tabraham P, Valmaggia L, Day F, Howes O, Wykes T, McGuire P. 0135 VERBAL SELF-MONITORING IN PEOPLE AT HIGH RISK OF PSYCHOSIS Schizophrenia Research. 86: S86. DOI: 10.1016/S0920-9964(06)70257-2 |
0.406 |
|
| 2006 |
Tabraham P, Brett C, Johns L, Broome M, Woolley J, Bramon E, Howes O, McGuire P. 0118 SPATIAL WORKING MEMORY IS IMPAIRED IN INDIVIDUALS AT HIGH RISK FOR PSYCHOSIS Schizophrenia Research. 86: S85. DOI: 10.1016/S0920-9964(06)70253-5 |
0.401 |
|
| 2006 |
Howes O, Montgomery A, Asselin M, Murray R, Grasby P, McGuire P. WC4E THE PRE-SYNAPTIC DOPAMINERGIC SYSTEM BEFORE AND AFTER THE ONSET OF PSYCHOSIS: INITIAL RESULTS FROM AN ONGOING [18F]FLUORO-DOPA PET STUDY Schizophrenia Research. 86: S11. DOI: 10.1016/S0920-9964(06)70033-0 |
0.394 |
|
| 2006 |
Tabraham P, Valmaggia L, Johns L, Broome M, Woolley J, Howes O, McGuire P. WC1A TAKING THE CAARMS TO LONDON Schizophrenia Research. 86: S4. DOI: 10.1016/S0920-9964(06)70012-3 |
0.358 |
|
| 2004 |
Howes OD, McDonald C, Cannon M, Arseneault L, Boydell J, Murray RM. Pathways to schizophrenia: The impact of environmental factors International Journal of Neuropsychopharmacology. 7: S7-S13. PMID 14972079 DOI: 10.1017/S1461145704004122 |
0.31 |
|
| 2004 |
Howes O. Bone mineral density and prolactin associations in patients with chronic schizophrenia [3] Schizophrenia Research. 66: 77-78. PMID 14693356 DOI: 10.1016/S0920-9964(03)00054-9 |
0.331 |
|
| 2003 |
Howes O, Ohlsen R, Pilowsky LS. Effect of clozapine on mortality [3] British Journal of Psychiatry. 183: 460. PMID 14594927 DOI: 10.1192/Bjp.183.5.460 |
0.329 |
|
| 2002 |
Howes O, Smith S. Hyperprolactinaemia caused by antipsychotic drugs. Endocrine antipsychotic side effects must be systemically assessed. Bmj. 324: 1278-1278. DOI: 10.1136/Bmj.324.7348.1278 |
0.344 |
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