Charlotte M. Fare - Publications

University of Pennsylvania, Philadelphia, PA, United States 
biochemistry, biophysics, neurodegeneration

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Fare CM, Rhine K, Lam A, Myong S, Shorter J. A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity. The Journal of Biological Chemistry. 102806. PMID 36529289 DOI: 10.1016/j.jbc.2022.102806  0.661
2022 Shen H, Yanas A, Owens MC, Zhang C, Fritsch C, Fare CM, Copley KE, Shorter J, Goldman YE, Liu KF. Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation. Molecular Cell. PMID 35588748 DOI: 10.1016/j.molcel.2022.04.022  0.741
2022 Kim HJ, Mohassel P, Donkervoort S, Guo L, O'Donovan K, Coughlin M, Lornage X, Foulds N, Hammans SR, Foley AR, Fare CM, Ford AF, Ogasawara M, Sato A, Iida A, et al. Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy. Nature Communications. 13: 2306. PMID 35484142 DOI: 10.1038/s41467-022-30015-1  0.73
2022 Rhine K, Dasovich M, Yoniles J, Badiee M, Skanchy S, Ganser LR, Ge Y, Fare CM, Shorter J, Leung AKL, Myong S. Poly(ADP-ribose) drives condensation of FUS via a transient interaction. Molecular Cell. PMID 35182479 DOI: 10.1016/j.molcel.2022.01.018  0.605
2021 Odeh HM, Fare CM, Shorter J. Nuclear-import receptors counter deleterious phase transitions in neurodegenerative disease. Journal of Molecular Biology. 167220. PMID 34464655 DOI: 10.1016/j.jmb.2021.167220  0.79
2021 Beijer D, Kim HJ, Guo L, O'Donovan K, Mademan I, Deconinck T, Van Schil K, Fare CM, Drake LE, Ford AF, Kochański A, Kabzińska D, Dubuisson N, Van den Bergh P, Voermans NC, et al. Characterization of HNRNPA1 mutations defines diversity in pathogenic mechanisms and clinical presentation. Jci Insight. 6. PMID 34291734 DOI: 10.1172/jci.insight.148363  0.727
2021 Fare CM, Villani A, Drake LE, Shorter J. Higher-order organization of biomolecular condensates. Open Biology. 11: 210137. PMID 34129784 DOI: 10.1098/rsob.210137  0.461
2021 Fare CM, Shorter J. (Dis)Solving the problem of aberrant protein states. Disease Models & Mechanisms. 14. PMID 33942880 DOI: 10.1242/dmm.048983  0.58
2021 Fare CM, Shorter J. Open Access: A Role for p53 in c9ALS/FTD? Trends in Genetics : Tig. PMID 33551183 DOI: 10.1016/j.tig.2021.01.008  0.524
2020 Hutten S, Usluer S, Bourgeois B, Simonetti F, Odeh HM, Fare CM, Czuppa M, Hruska-Plochan M, Hofweber M, Polymenidou M, Shorter J, Edbauer D, Madl T, Dormann D. Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions. Cell Reports. 33: 108538. PMID 33357437 DOI: 10.1016/j.celrep.2020.108538  0.775
2020 Rhine K, Makurath MA, Liu J, Skanchy S, Lopez C, Catalan KF, Ma Y, Fare CM, Shorter J, Ha T, Chemla YR, Myong S. ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS. Molecular Cell. 80: 1139. PMID 33338404 DOI: 10.1016/j.molcel.2020.11.031  0.534
2019 Niaki AG, Sarkar J, Cai X, Rhine K, Vidaurre V, Guy B, Hurst M, Lee JC, Koh HR, Guo L, Fare CM, Shorter J, Myong S. Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations. Molecular Cell. PMID 31630970 DOI: 10.1016/J.Molcel.2019.09.022  0.726
2019 Guo L, Fare CM, Shorter J. Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors. Trends in Cell Biology. PMID 30660504 DOI: 10.1016/J.Tcb.2018.12.004  0.728
2018 Guo L, Kim HJ, Wang H, Monaghan J, Freyermuth F, Sung JC, O'Donovan K, Fare CM, Diaz Z, Singh N, Zhang ZC, Coughlin M, Sweeny EA, DeSantis ME, Jackrel ME, et al. Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains. Cell. 173: 677-692.e20. PMID 29677512 DOI: 10.1016/J.Cell.2018.03.002  0.683
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