Elizabeth Sweeny - Publications

University of Pennsylvania, Philadelphia, PA, United States 

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Richter SM, Massman LC, Stuehr DJ, Sweeny EA. Functional interactions between NADPH oxidase 5 and actin. Frontiers in Cell and Developmental Biology. 11: 1116833. PMID 36776559 DOI: 10.3389/fcell.2023.1116833  0.609
2022 Stuehr DJ, Dai Y, Biswas P, Sweeny EA, Ghosh A. New roles for GAPDH, Hsp90, and NO in regulating heme allocation and hemeprotein function in mammals. Biological Chemistry. PMID 36152339 DOI: 10.1515/hsz-2022-0197  0.683
2022 Tupta B, Stuehr E, Sumi MP, Sweeny EA, Smith B, Stuehr DJ, Ghosh A. GAPDH is involved in the heme-maturation of myoglobin and hemoglobin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22099. PMID 34972240 DOI: 10.1096/fj.202101237RR  0.663
2021 Sweeny EA, Hunt AP, Batka AE, Schlanger S, Lehnert N, Stuehr DJ. Nitric oxide and heme-NO stimulate superoxide production by NADPH oxidase 5. Free Radical Biology & Medicine. 172: 252-263. PMID 34139309 DOI: 10.1016/j.freeradbiomed.2021.06.008  0.642
2020 Sweeny EA, Schlanger S, Stuehr DJ. Dynamic regulation of NADPH oxidase 5 by intracellular heme levels and cellular chaperones. Redox Biology. 36: 101656. PMID 32738790 DOI: 10.1016/J.Redox.2020.101656  0.667
2020 Dai Y, Sweeny EA, Schlanger S, Ghosh A, Stuehr DJ. GAPDH Delivers Heme to Soluble Guanylyl Cyclase. The Journal of Biological Chemistry. PMID 32358060 DOI: 10.1074/Jbc.Ra120.013802  0.675
2019 Sweeny EA, Tariq A, Gurpinar E, Go MS, Sochor MA, Kan ZY, Mayne L, Englander SW, Shorter J. Structural and mechanistic insights into Hsp104 function revealed by synchrotron x-ray footprinting. The Journal of Biological Chemistry. PMID 31882541 DOI: 10.1074/Jbc.Ra119.011577  0.706
2019 Tariq A, Lin J, Jackrel ME, Hesketh CD, Carman PJ, Mack KL, Weitzman R, Gambogi C, Hernandez Murillo OA, Sweeny EA, Gurpinar E, Yokom AL, Gates SN, Yee K, Sudesh S, et al. Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity. Cell Reports. 28: 2080-2095.e6. PMID 31433984 DOI: 10.1016/J.Celrep.2019.07.069  0.789
2019 Durie CL, Lin J, Scull NW, Mack KL, Jackrel ME, Sweeny EA, Castellano LM, Shorter J, Lucius AL. Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases. Biophysical Journal. PMID 31027887 DOI: 10.1016/J.Bpj.2019.03.035  0.816
2018 Sweeny EA, Singh AB, Chakravarti R, Martinez-Guzman O, Saini A, Haque MM, Garee G, Dans PD, Hannibal L, Reddi AR, Stuehr DJ. Glyceraldehyde 3-phosphate dehydrogenase is a chaperone that allocates labile heme in cells. The Journal of Biological Chemistry. PMID 30012884 DOI: 10.1074/Jbc.Ra118.004169  0.795
2018 Guo L, Kim HJ, Wang H, Monaghan J, Freyermuth F, Sung JC, O'Donovan K, Fare CM, Diaz Z, Singh N, Zhang ZC, Coughlin M, Sweeny EA, DeSantis ME, Jackrel ME, et al. Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains. Cell. 173: 677-692.e20. PMID 29677512 DOI: 10.1016/J.Cell.2018.03.002  0.76
2018 Ghosh A, Garee G, Sweeny EA, Nakamura Y, Stuehr DJ. Hsp90 chaperones hemoglobin maturation in erythroid and nonerythroid cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29358373 DOI: 10.1073/Pnas.1717993115  0.738
2018 Weaver CL, Jackrel ME, Lin J, Mack KL, Sweeny E, Duran EC, Shorter J, Lucius AL. Kinetic Mechanism of ATP-Dependent Disaggregating Motor Saccharomyces cerevisiae Hsp104 Biophysical Journal. 114: 553a. DOI: 10.1016/J.Bpj.2017.11.3021  0.767
2017 Gates SN, Yokom AL, Lin J, Jackrel ME, Rizo AN, Kendsersky NM, Buell CE, Sweeny EA, Mack KL, Chuang E, Torrente MP, Su M, Shorter J, Southworth DR. Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science (New York, N.Y.). PMID 28619716 DOI: 10.1126/Science.Aan1052  0.777
2017 Weaver CL, Duran EC, Mack KL, Lin J, Jackrel ME, Sweeny EA, Shorter J, Lucius AL. Avidity for polypeptide binding by nucleotide-bound Hsp104 structures. Biochemistry. PMID 28379007 DOI: 10.1021/Acs.Biochem.7B00225  0.797
2017 Burén S, Young EM, Sweeny EA, López-Torrejón G, Veldhuizen M, Voigt CA, Rubio LM. Formation of Nitrogenase NifDK Tetramers in the Mitochondria of Saccharomyces cerevisiae. Acs Synthetic Biology. PMID 28221768 DOI: 10.1021/Acssynbio.6B00371  0.286
2016 Sweeny EA, Shorter J. Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104. Journal of Molecular Biology. 428: 1870-85. PMID 26608812 DOI: 10.1016/J.Jmb.2015.11.016  0.71
2016 Sweeny EA, Shorter J. Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104 Journal of Molecular Biology. 428: 1870-1885. DOI: 10.1016/j.jmb.2015.11.016  0.7
2015 Sweeny EA, Jackrel ME, Go MS, Sochor MA, Razzo BM, DeSantis ME, Gupta K, Shorter J. The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation. Molecular Cell. 57: 836-49. PMID 25620563 DOI: 10.1016/J.Molcel.2014.12.021  0.84
2014 Desantis ME, Sweeny EA, Snead D, Leung EH, Go MS, Gupta K, Wendler P, Shorter J. Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation. The Journal of Biological Chemistry. 289: 848-67. PMID 24280225 DOI: 10.1074/Jbc.M113.520759  0.835
2013 DeSantis ME, Leung EH, Sweeny EA, Jackrel ME, Cushman-Nick M, Neuhaus-Follini A, Vashist S, Sochor MA, Knight MN, Shorter J. Inter-Subunit Coordination in Hsp104, a Protein Disaggregase Biophysical Journal. 104: 571a. DOI: 10.1016/J.Bpj.2012.11.3173  0.767
2013 Sweeny EA, Gupta K, Shorter J. Conformational Changes of Hsp104 Revealed through Small Angle X-Ray Scattering (SAXS) Biophysical Journal. 104: 182a. DOI: 10.1016/J.Bpj.2012.11.1026  0.711
2012 DeSantis ME, Leung EH, Sweeny EA, Jackrel ME, Cushman-Nick M, Neuhaus-Follini A, Vashist S, Sochor MA, Knight MN, Shorter J. Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients. Cell. 151: 778-93. PMID 23141537 DOI: 10.1016/J.Cell.2012.09.038  0.767
2011 Sweeny EA, DeSantis ME, Shorter J. Purification of hsp104, a protein disaggregase Journal of Visualized Experiments : Jove. PMID 21989490 DOI: 10.3791/3190  0.834
2009 Roberts BE, Duennwald ML, Wang H, Chung C, Lopreiato NP, Sweeny EA, Knight MN, Shorter J. A synergistic small-molecule combination directly eradicates diverse prion strain structures. Nature Chemical Biology. 5: 936-46. PMID 19915541 DOI: 10.1038/Nchembio.246  0.532
2008 Sweeny EA, Shorter J. Prion proteostasis: Hsp104 meets its supporting cast Prion. 2: 135-140. PMID 19242125 DOI: 10.4161/Pri.2.4.7952  0.674
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