Year |
Citation |
Score |
2023 |
Foley KE, Winder Z, Sudduth TL, Martin BJ, Nelson PT, Jicha GA, Harp JP, Weekman EM, Wilcock DM. Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38011580 DOI: 10.1002/alz.13485 |
0.515 |
|
2023 |
Niedowicz DM, Gollihue JL, Weekman EM, Phe P, Wilcock DM, Norris CM, Nelson PT. Using digital pathology to analyze the murine cerebrovasculature. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X231216142. PMID 37988134 DOI: 10.1177/0271678X231216142 |
0.477 |
|
2023 |
Foley KE, Weekman EM, Wilcock DM. Mechanisms of ARIA: is it time to focus on the unique immune environment of the neurovascular unit? Molecular Neurodegeneration. 18: 76. PMID 37858154 DOI: 10.1186/s13024-023-00667-8 |
0.435 |
|
2023 |
Weekman EM, Johnson SN, Rogers CB, Sudduth TL, Xie K, Qiao Q, Fardo DW, Bottiglieri T, Wilcock DM. Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes. Journal of Neuroinflammation. 20: 199. PMID 37658433 DOI: 10.1186/s12974-023-02883-x |
0.617 |
|
2023 |
Kloske CM, Gearon MD, Weekman EM, Rogers C, Patel E, Bachstetter A, Nelson PT, Wilcock DM. Association between APOE genotype and microglial cell morphology. Journal of Neuropathology and Experimental Neurology. PMID 37087107 DOI: 10.1093/jnen/nlad031 |
0.574 |
|
2023 |
Sompol P, Gollihue JL, Weiss BE, Lin RL, Case SL, Kraner SD, Weekman EM, Gant JC, Rogers CB, Niedowicz DM, Sudduth TL, Powell DK, Lin AL, Nelson PT, Thibault O, et al. Targeting astrocyte signaling alleviates cerebrovascular and synaptic function deficits in a diet-based mouse model of small cerebral vessel disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36746627 DOI: 10.1523/JNEUROSCI.1333-22.2023 |
0.569 |
|
2022 |
Weekman EM, Winder Z, Rogers CB, Abner EL, Sudduth TL, Patel E, Dugan AJ, Fister SX, Wasek B, Nelson PT, Jicha GA, Bottiglieri T, Fardo DW, Wilcock DM. Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue. Alzheimer's & Dementia (New York, N. Y.). 8: e12368. PMID 36514441 DOI: 10.1002/trc2.12368 |
0.58 |
|
2022 |
Seaks CE, Weekman EM, Sudduth TL, Xie K, Wasek B, Fardo DW, Johnson LA, Bottiglieri T, Wilcock DM. Apolipoprotein E ε4/4 genotype limits response to dietary induction of hyperhomocysteinemia and resulting inflammatory signaling. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211069006. PMID 35023380 DOI: 10.1177/0271678X211069006 |
0.616 |
|
2021 |
Linton AE, Weekman EM, Wilcock DM. Pathologic sequelae of vascular cognitive impairment and dementia sheds light on potential targets for intervention. Cerebral Circulation - Cognition and Behavior. 2: 100030. PMID 36324710 DOI: 10.1016/j.cccb.2021.100030 |
0.675 |
|
2021 |
Kloske CM, Dugan AJ, Weekman EM, Winder Z, Patel E, Nelson PT, Fardo DW, Wilcock DM. Inflammatory Pathways Are Impaired in Alzheimer Disease and Differentially Associated With Apolipoprotein E Status. Journal of Neuropathology and Experimental Neurology. PMID 34486652 DOI: 10.1093/jnen/nlab085 |
0.595 |
|
2020 |
Price BR, Sudduth TL, Weekman EM, Johnson S, Hawthorne D, Woolums A, Wilcock DM. Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition. Journal of Neuroinflammation. 17: 238. PMID 32795308 DOI: 10.1186/s12974-020-01915-0 |
0.762 |
|
2020 |
Weekman EM, Lee T, Price BR, Woolums AE, Hawthorne D, IV CES, Wilcock DM. Hyperhomocysteinemia as a model of VCID Alzheimer's & Dementia. 16. DOI: 10.1002/alz.039888 |
0.706 |
|
2019 |
Weekman EM, Sudduth TL, Price BR, Woolums AE, Hawthorne D, Seaks CE, Wilcock DM. Time course of neuropathological events in hyperhomocysteinemic amyloid depositing mice reveals early neuroinflammatory changes that precede amyloid changes and cerebrovascular events. Journal of Neuroinflammation. 16: 284. PMID 31888650 DOI: 10.1186/s12974-019-1685-z |
0.76 |
|
2019 |
Price BR, Sudduth TL, Weekman EM, Woolums A, Hawthorne D, Rosenthal A, Wilcock DM. THERAPEUTIC TARGETING OF TREM2 BY AN ACTIVATING ANTIBODY AMELIORATES AMYLOID-BETA DEPOSITION AND IMPROVES COGNITION IN THE 5XFAD MODEL OF ALZHEIMER’S DISEASE Alzheimer's & Dementia. 15: P214. DOI: 10.1016/j.jalz.2019.06.4559 |
0.754 |
|
2018 |
Price BR, Wilcock DM, Weekman EM. Hyperhomocysteinemia as a Risk Factor for Vascular Contributions to Cognitive Impairment and Dementia. Frontiers in Aging Neuroscience. 10: 350. PMID 30429785 DOI: 10.3389/fnagi.2018.00350 |
0.753 |
|
2017 |
Weekman EM, Woolums AE, Sudduth TL, Wilcock DM. Hyperhomocysteinemia-Induced Gene Expression Changes in the Cell Types of the Brain. Asn Neuro. 9: 1759091417742296. PMID 29198136 DOI: 10.1177/1759091417742296 |
0.602 |
|
2017 |
Price BR, Sudduth TL, Weekman EM, Wilcock DM, Woolums A. [P1–004]: ASTROCYTE RESPONSE TO HYPERHOMOCYSTEINEMIA (HHCY) Alzheimer's & Dementia. 13. DOI: 10.1016/j.jalz.2017.06.071 |
0.723 |
|
2017 |
Price BR, Sudduth TL, Weekman EM, Wilcock DM, Woolums A. [P1–198]: ASTROCYTE RESPONSE TO HYPERHOMOCYSTEINEMIA (HHCY) Alzheimer's & Dementia. 13. DOI: 10.1016/j.jalz.2017.06.018 |
0.723 |
|
2016 |
Sudduth TL, Weekman EM, Price BR, Gooch JL, Woolums A, Norris CM, Wilcock DM. Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID). Neuroscience. PMID 27890830 DOI: 10.1016/J.Neuroscience.2016.11.024 |
0.769 |
|
2016 |
Weekman EM, Sudduth TL, Caverly CN, Kopper TJ, Phillips OW, Powell DK, Wilcock DM. Reduced Efficacy of Anti-Aβ Immunotherapy in a Mouse Model of Amyloid Deposition and Vascular Cognitive Impairment Comorbidity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9896-907. PMID 27656027 DOI: 10.1523/JNEUROSCI.1762-16.2016 |
0.623 |
|
2016 |
Hainsworth AH, Yeo NE, Weekman EM, Wilcock DM. Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID). Biochimica Et Biophysica Acta. 1862: 1008-17. PMID 26689889 DOI: 10.1016/j.bbadis.2015.11.015 |
0.567 |
|
2016 |
Wilcock DM, Sudduth TL, Weekman EM, Pleiss MM, Woolums A, Norris CM. Neurovascular Astrocyte Dysfunction As A Key Mediator Of Vascular Cognitive Impairment Alzheimers & Dementia. 12: 270. DOI: 10.1016/J.Jalz.2016.06.489 |
0.588 |
|
2015 |
Weekman EM, Wilcock DM. Matrix Metalloproteinase in Blood-Brain Barrier Breakdown in Dementia. Journal of Alzheimer's Disease : Jad. 49: 893-903. PMID 26599057 DOI: 10.3233/JAD-150759 |
0.551 |
|
2015 |
Latta CH, Sudduth TL, Weekman EM, Brothers HM, Abner EL, Popa GJ, Mendenhall MD, Gonzalez-Oregon F, Braun K, Wilcock DM. Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice. Journal of Neuroinflammation. 12: 41. PMID 25885682 DOI: 10.1186/S12974-015-0243-6 |
0.565 |
|
2014 |
Weekman EM, Sudduth TL, Abner EL, Popa GJ, Mendenhall MD, Brothers HM, Braun K, Greenstein A, Wilcock DM. Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice. Journal of Neuroinflammation. 11: 127. PMID 25062954 DOI: 10.1186/1742-2094-11-127 |
0.537 |
|
2014 |
Sudduth TL, Weekman EM, Brothers HM, Braun K, Wilcock DM. β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice. Alzheimer's Research & Therapy. 6: 32. PMID 24991237 DOI: 10.1186/alzrt262 |
0.61 |
|
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