Dwight Charles German, Ph.D. - Publications

Affiliations: 
Psychiiatry University of Texas Siuthwestern 
Area:
Dopamine, Parkinson's Disease

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Sonsalla PK, Coleman C, Wong LY, Harris SL, Richardson JR, Gadad BS, Li W, German DC. The angiotensin converting enzyme inhibitor captopril protects nigrostriatal dopamine neurons in animal models of parkinsonism. Experimental Neurology. 250: 376-83. PMID 24184050 DOI: 10.1016/j.expneurol.2013.10.014  0.324
2012 Sonsalla PK, Wong LY, Harris SL, Richardson JR, Khobahy I, Li W, Gadad BS, German DC. Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's disease. Experimental Neurology. 234: 482-7. PMID 22309831 DOI: 10.1016/j.expneurol.2012.01.022  0.367
2012 Lee KW, Zhao X, Im JY, Grosso H, Jang WH, Chan TW, Sonsalla PK, German DC, Ichijo H, Junn E, Mouradian MM. Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation. Plos One. 7: e29935. PMID 22253830 DOI: 10.1371/journal.pone.0029935  0.317
2008 Sonsalla PK, Zeevalk GD, German DC. Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinson's disease. Parkinsonism & Related Disorders. 14: S116-8. PMID 18583172 DOI: 10.1016/j.parkreldis.2008.04.008  0.318
2007 Liang CL, Wang TT, Luby-Phelps K, German DC. Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease. Experimental Neurology. 203: 370-80. PMID 17010972 DOI: 10.1016/j.expneurol.2006.08.015  0.527
2006 Yazdani U, German DC, Liang CL, Manzino L, Sonsalla PK, Zeevalk GD. Rat model of Parkinson's disease: chronic central delivery of 1-methyl-4-phenylpyridinium (MPP+). Experimental Neurology. 200: 172-83. PMID 16546169 DOI: 10.1016/j.expneurol.2006.02.002  0.347
2005 German DC, Nelson O, Liang F, Liang CL, Games D. The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage. The Journal of Comparative Neurology. 492: 469-76. PMID 16228992 DOI: 10.1002/cne.20744  0.353
2004 Liang CL, Nelson O, Yazdani U, Pasbakhsh P, German DC. Inverse relationship between the contents of neuromelanin pigment and the vesicular monoamine transporter-2: human midbrain dopamine neurons. The Journal of Comparative Neurology. 473: 97-106. PMID 15067721 DOI: 10.1002/cne.20098  0.535
2001 German DC, Quintero EM, Liang CL, Ng B, Punia S, Xie C, Dietschy JM. Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease. The Journal of Comparative Neurology. 433: 415-25. PMID 11298365 DOI: 10.1002/cne.1149  0.418
2000 German DC, Liang CL, Manaye KF, Lane K, Sonsalla PK. Pharmacological inactivation of the vesicular monoamine transporter can enhance 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration of midbrain dopaminergic neurons, but not locus coeruleus noradrenergic neurons. Neuroscience. 101: 1063-9. PMID 11113355 DOI: 10.1016/S0306-4522(00)00385-7  0.481
1999 German DC, Manaye KF, Wu D, Hersh LB, Zweig RM. Mesopontine cholinergic and non-cholinergic neurons in schizophrenia. Neuroscience. 94: 33-8. PMID 10613494 DOI: 10.1016/S0306-4522(99)00305-X  0.498
1999 Holt DJ, Herman MM, Hyde TM, Kleinman JE, Sinton CM, German DC, Hersh LB, Graybiel AM, Saper CB. Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia. Neuroscience. 94: 21-31. PMID 10613493 DOI: 10.1016/S0306-4522(99)00279-1  0.349
1999 Manaye KF, Zweig R, Wu D, Hersh LB, De Lacalle S, Saper CB, German DC. Quantification of cholinergic and select non-cholinergic mesopontine neuronal populations in the human brain. Neuroscience. 89: 759-70. PMID 10199611 DOI: 10.1016/S0306-4522(98)00380-7  0.563
1998 Speciale SG, Liang CL, Sonsalla PK, Edwards RH, German DC. The neurotoxin 1-methyl-4-phenylpyridinium is sequestered within neurons that contain the vesicular monoamine transporter. Neuroscience. 84: 1177-85. PMID 9578404 DOI: 10.1016/S0306-4522(97)00570-8  0.394
1997 Sonsalla PK, Manzino L, Sinton CM, Liang CL, German DC, Zeevalk GD. Inhibition of striatal energy metabolism produces cell loss in the ipsilateral substantia nigra. Brain Research. 773: 223-6. PMID 9409726 DOI: 10.1016/S0006-8993(97)00941-4  0.526
1997 Sanghera MK, Manaye K, McMahon A, Sonsalla PK, German DC. Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP. Neuroreport. 8: 3327-31. PMID 9351666 DOI: 10.1097/00001756-199710200-00027  0.567
1996 Liang CL, Sinton CM, Sonsalla PK, German DC. Midbrain dopaminergic neurons in the mouse that contain calbindin-D28k exhibit reduced vulnerability to MPTP-induced neurodegeneration. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 313-8. PMID 9117542 DOI: 10.1006/neur.1996.0042  0.556
1996 German DC, Nelson EL, Liang CL, Speciale SG, Sinton CM, Sonsalla PK. The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouse. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 299-312. PMID 9117541 DOI: 10.1006/Neur.1996.0041  0.569
1996 McMahon A, Lephart ED, Chi S, Lee M, Iacopino AM, German DC. Calbindin-D28K in the nucleus of nerve growth factor-treated PC12 cells. Neuroreport. 7: 2419-22. PMID 8981395 DOI: 10.1097/00001756-199611040-00003  0.365
1996 Ng MC, Iacopino AM, Quintero EM, Marches F, Sonsalla PK, Liang CL, Speciale SG, German DC. The neurotoxin MPTP increases calbindin-D28k levels in mouse midbrain dopaminergic neurons. Brain Research. Molecular Brain Research. 36: 329-36. PMID 8965654 DOI: 10.1016/0169-328X(95)00266-U  0.342
1996 Liang CL, Sinton CM, German DC. Midbrain dopaminergic neurons in the mouse: co-localization with Calbindin-D28K and calretinin. Neuroscience. 75: 523-33. PMID 8931015 DOI: 10.1016/0306-4522(96)00228-X  0.4
1996 Nelson EL, Liang CL, Sinton CM, German DC. Midbrain dopaminergic neurons in the mouse: computer-assisted mapping. The Journal of Comparative Neurology. 369: 361-71. PMID 8743418 DOI: 10.1002/(Sici)1096-9861(19960603)369:3<361::Aid-Cne3>3.0.Co;2-3  0.563
1995 Sanghera MK, Zamora JL, German DC. Calbindin-D28k-containing neurons in the human hypothalamus: relationship to dopaminergic neurons. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 4: 375-81. PMID 8846230 DOI: 10.1006/neur.1995.0045  0.524
1995 Manaye KF, McIntire DD, Mann DM, German DC. Locus coeruleus cell loss in the aging human brain: a non-random process. The Journal of Comparative Neurology. 358: 79-87. PMID 7560278 DOI: 10.1002/Cne.903580105  0.474
1994 Sanghera MK, Manaye KF, Liang CL, Lacopino AM, Bannon MJ, German DC. Low dopamine transporter mRNA levels in midbrain regions containing calbindin. Neuroreport. 5: 1641-4. PMID 7819538 DOI: 10.1097/00001756-199408150-00025  0.616
1993 German DC, Manaye KF. Midbrain dopaminergic neurons (nuclei A8, A9, and A10): three-dimensional reconstruction in the rat. The Journal of Comparative Neurology. 331: 297-309. PMID 8514911 DOI: 10.1002/Cne.903310302  0.503
1993 German DC, Liang CL. Neuroactive peptides exist in the midbrain dopaminergic neurons that contain calbindin-D28k. Neuroreport. 4: 491-4. PMID 8513124 DOI: 10.1097/00001756-199305000-00007  0.549
1993 Speciale SG, Manaye KF, Sadeq M, German DC. Opioid receptors in midbrain dopaminergic regions of the rat. II. Kappa and delta receptor autoradiography. Journal of Neural Transmission. General Section. 91: 53-66. PMID 8383985 DOI: 10.1007/Bf01244918  0.465
1993 German DC, Speciale SG, Manaye KF, Sadeq M. Opioid receptors in midbrain dopaminergic regions of the rat. I. Mu receptor autoradiography. Journal of Neural Transmission. General Section. 91: 39-52. PMID 8383984 DOI: 10.1007/Bf01244917  0.484
1993 Liang CL, Kozlowski GP, German DC. Leucine5-enkephalin afferents to midbrain dopaminergic neurons: light and electron microscopic examination. The Journal of Comparative Neurology. 332: 269-81. PMID 8101195 DOI: 10.1002/cne.903320302  0.327
1992 German DC, Manaye KF, White CL, Woodward DJ, McIntire DD, Smith WK, Kalaria RN, Mann DM. Disease-specific patterns of locus coeruleus cell loss. Annals of Neurology. 32: 667-76. PMID 1449247 DOI: 10.1002/Ana.410320510  0.331
1992 Liang CL, Kozlowski GP, Joseph SA, German DC. ACTH1-39 inputs to mesocorticolimbic dopaminergic neurons: light and electron microscopic examination. Neuroscience Letters. 146: 79-83. PMID 1361979 DOI: 10.1016/0304-3940(92)90177-9  0.43
1992 German DC, Manaye KF, Sonsalla PK, Brooks BA. Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells. Annals of the New York Academy of Sciences. 648: 42-62. PMID 1353337 DOI: 10.1111/j.1749-6632.1992.tb24523.x  0.382
1992 Gu X, Blatz AL, German DC. Subtypes of substantia nigra dopaminergic neurons revealed by apamin: autoradiographic and electrophysiological studies. Brain Research Bulletin. 28: 435-40. PMID 1350500 DOI: 10.1016/0361-9230(92)90044-X  0.548
1992 Iacopino A, Christakos S, German D, Sonsalla PK, Altar CA. Calbindin-D28K-containing neurons in animal models of neurodegeneration: possible protection from excitotoxicity. Brain Research. Molecular Brain Research. 13: 251-61. PMID 1317497 DOI: 10.1016/0169-328X(92)90033-8  0.414
1991 Saper CB, Sorrentino DM, German DC, de Lacalle S. Medullary catecholaminergic neurons in the normal human brain and in Parkinson's disease. Annals of Neurology. 29: 577-84. PMID 1892359 DOI: 10.1002/Ana.410290602  0.518
1991 Bernardini GL, Gu X, German DC. Nucleus A10 dopaminergic neurons in inbred mouse strains: firing rate and autoreceptor sensitivity are independent of the number of cells in the nucleus. Brain Research Bulletin. 27: 163-8. PMID 1742603 DOI: 10.1016/0361-9230(91)90062-O  0.531
1991 Bernardini GL, Gu X, Viscardi E, German DC. Amphetamine-induced and spontaneous release of dopamine from A9 and A10 cell dendrites: an in vitro electrophysiological study in the mouse. Journal of Neural Transmission. General Section. 84: 183-93. PMID 1679335 DOI: 10.1007/Bf01244969  0.418
1990 Bernardini GL, Speciale SG, German DC. Increased midbrain dopaminergic cell activity following 2'CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study. Brain Research. 527: 123-9. PMID 1980838 DOI: 10.1016/0006-8993(90)91069-S  0.441
1989 German DC, Manaye K, Smith WK, Woodward DJ, Saper CB. Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization. Annals of Neurology. 26: 507-14. PMID 2817827 DOI: 10.1002/Ana.410260403  0.504
1989 Manaye KF, Sonsalla PK, Barnett G, Heikkila RE, Woodward DJ, Smith WK, German DC. 1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'CH3-MPTP)-induced degeneration of mesostriatal dopaminergic neurons in the mouse: biochemical and neuroanatomical studies. Brain Research. 491: 307-15. PMID 2765888 DOI: 10.1016/0006-8993(89)90065-6  0.454
1989 Mattiace LA, Baring MD, Manaye KF, Mihailoff GA, German DC. Mesostriatal projections in BALB/c and CBA mice: a quantitative retrograde neuroanatomical tracing study. Brain Research Bulletin. 23: 61-8. PMID 2478265 DOI: 10.1016/0361-9230(89)90164-0  0.573
1988 German DC, Walker BS, Manaye K, Smith WK, Woodward DJ, North AJ. The human locus coeruleus: computer reconstruction of cellular distribution. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 1776-88. PMID 3367220 DOI: 10.1523/Jneurosci.08-05-01776.1988  0.384
1988 German DC, Dubach M, Askari S, Speciale SG, Bowden DM. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian syndrome in Macaca fascicularis: which midbrain dopaminergic neurons are lost? Neuroscience. 24: 161-74. PMID 3259295 DOI: 10.1016/0306-4522(88)90320-X  0.557
1988 Shepard PD, German DC. Electrophysiological and pharmacological evidence for the existence of distinct subpopulations of nigrostriatal dopaminergic neuron in the rat. Neuroscience. 27: 537-46. PMID 3217003 DOI: 10.1016/0306-4522(88)90287-4  0.721
1988 Shepard PD, Mihailoff GA, German DC. Anatomical and electrophysiological characterization of presumed dopamine-containing neurons within the supramammillary region of the rat. Brain Research Bulletin. 20: 307-14. PMID 2896530 DOI: 10.1016/0361-9230(88)90060-3  0.733
1987 German DC, White CL, Sparkman DR. Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex. Neuroscience. 21: 305-12. PMID 3302759 DOI: 10.1016/0306-4522(87)90123-0  0.303
1987 Dubach M, Schmidt R, Kunkel D, Bowden DM, Martin R, German DC. Primate neostriatal neurons containing tyrosine hydroxylase: immunohistochemical evidence. Neuroscience Letters. 75: 205-10. PMID 2883616 DOI: 10.1016/0304-3940(87)90298-9  0.547
1987 Saper CB, Wainer BH, German DC. Axonal and transneuronal transport in the transmission of neurological disease: potential role in system degenerations, including Alzheimer's disease. Neuroscience. 23: 389-98. PMID 2449630 DOI: 10.1016/0306-4522(87)90063-7  0.398
1987 Saper CB, German DC. Hypothalamic pathology in Alzheimer's disease. Neuroscience Letters. 74: 364-70. PMID 2436113 DOI: 10.1016/0304-3940(87)90325-9  0.509
1986 Speciale SG, Miller JD, McMillen BA, German DC. Activation of specific central dopamine pathways: locomotion and footshock. Brain Research Bulletin. 16: 33-8. PMID 3955388 DOI: 10.1016/0361-9230(86)90009-2  0.432
1986 Matthews RT, German DC. Evidence for a functional role of dopamine type-1 (D-1) receptors in the substantia nigra of rats. European Journal of Pharmacology. 120: 87-93. PMID 2868905 DOI: 10.1016/0014-2999(86)90644-8  0.607
1985 Saper CB, German DC, White CL. Neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the Alzheimer's type: possible role in cell loss. Neurology. 35: 1089-95. PMID 4022341 DOI: 10.1212/Wnl.35.8.1089  0.487
1985 German DC, Bruce G, Hersh LB. Immunohistochemical staining of cholinergic neurons in the human brain using a polyclonal antibody to human choline acetyltransferase. Neuroscience Letters. 61: 1-5. PMID 3908999 DOI: 10.1016/0304-3940(85)90391-X  0.407
1984 Shepard PD, German DC. A subpopulation of mesocortical dopamine neurons possesses autoreceptors. European Journal of Pharmacology. 98: 455-6. PMID 6723785 DOI: 10.1016/0014-2999(84)90300-5  0.728
1984 Miller JD, Speciale SG, McMillen BA, German DC. Naloxone antagonism of stress-induced augmentation of frontal cortex dopamine metabolism. European Journal of Pharmacology. 98: 437-9. PMID 6723781 DOI: 10.1016/0014-2999(84)90295-4  0.338
1984 Matthews RT, German DC. Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine. Neuroscience. 11: 617-25. PMID 6717805 DOI: 10.1016/0306-4522(84)90048-4  0.491
1984 Sanghera MK, Trulson ME, German DC. Electrophysiological properties of mouse dopamine neurons: in vivo and in vitro studies. Neuroscience. 12: 793-801. PMID 6472621 DOI: 10.1016/0306-4522(84)90171-4  0.558
1984 Matthews RT, McMillen BA, Speciale SG, Jarrah H, Shore PA, Sanghera MK, Shepard PD, German DC. Effects of zoxazolamine and related centrally acting muscle relaxants on nigrostriatal dopaminergic neurons. Brain Research Bulletin. 12: 479-86. PMID 6467036 DOI: 10.1016/0361-9230(84)90163-1  0.7
1984 German DC, Shepard PD. SOME CORTICAL-PROJECTING DOPAMINERGIC NEURONS POSSESS AUTORECEPTORS Clinical Neuropharmacology. 7: S40. DOI: 10.1097/00002826-198406001-00039  0.691
1983 Miller JD, Farber J, Gatz P, Roffwarg H, German DC. Activity of mesencephalic dopamine and non-dopamine neurons across stages of sleep and walking in the rat. Brain Research. 273: 133-41. PMID 6616218 DOI: 10.1016/0006-8993(83)91101-0  0.399
1983 German DC, Schlusselberg DS, Woodward DJ. Three-dimensional computer reconstruction of midbrain dopaminergic neuronal populations: from mouse to man. Journal of Neural Transmission. 57: 243-54. PMID 6140298 DOI: 10.1007/BF01248996  0.524
1983 McMillen BA, Matthews RT, Sanghera MK, Shepard PD, German DC. Dopamine receptor antagonism by the novel antianxiety drug, buspirone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 733-8. PMID 6131948 DOI: 10.1523/Jneurosci.03-04-00733.1983  0.587
1982 Sanghera MK, McMillen BA, German DC. Buspirone, a non-benzodiazepine anxiolytic, increases locus coeruleus noradrenergic neuronal activity. European Journal of Pharmacology. 86: 107-10. PMID 6130954 DOI: 10.1016/0014-2999(82)90406-X  0.405
1982 German DC. Dopamine neurons, reward and behavior Behavioral and Brain Sciences. 5: 59-60. DOI: 10.1017/S0140525X00010438  0.473
1981 Browder S, German DC, Shore PA. Midbrain dopamine neurons: differential responses to amphetamine isomers. Brain Research. 207: 333-42. PMID 7470912 DOI: 10.1016/0006-8993(81)90368-1  0.479
1981 German DC, McMillen BA, Sanghera MK, Saffer SI, Shore PA. Effects of severe dopamine depletion on dopamine neuronal impulse flow and on tyrosine hydroxylase regulation. Brain Research Bulletin. 6: 131-4. PMID 6110470 DOI: 10.1016/S0361-9230(81)80037-8  0.433
1980 McMillen BA, German DC, Sanghere MK, Warnack W, Shore PA. Pimozide: delayed onset of action at rat striatal pre- and postsynaptic dopamine receptors. The Journal of Pharmacology and Experimental Therapeutics. 215: 150-5. PMID 6109013  0.301
1979 German DC, Sanghera MK, Kiser RS, McMillen BA, Shore PA. Electrophysiological and biochemical responses of noradrenergic neurons to a non-amphetamine CNS stimulant. Brain Research. 166: 331-9. PMID 427592 DOI: 10.1016/0006-8993(79)90218-X  0.474
1979 Sanghera MK, German DC, Kiser RS, Shore PA. Differences in norepinephrine and dopamine neurotransmitter storage systems. Brain Research Bulletin. 4: 217-21. PMID 223744 DOI: 10.1016/0361-9230(79)90285-5  0.435
1979 German DC, Harden H, Sanghera MK, Mann D, Kiser RS, Miller HH, Shore PA. Dopaminergic neuronal responses to a non-amphetamine CNS stimulant. Journal of Neural Transmission. 44: 39-49. PMID 35584 DOI: 10.1007/BF01252700  0.43
1979 Browder S, German DC, Kiser RS, Shore PA. Differential responses of substantia nigra and ventral tegmental dopamine neurons to amphetamine isomers Federation Proceedings. 38: No. 3318.  0.516
1979 Sanghera MK, German DC, Kiser RS. Dopamine neuronal activity during operant behavior Federation Proceedings. 38: No.158.  0.442
1976 German DC, Fetz EE. Responses of primate locus coeruleus and subcoeruleus neurons to stimulation at reinforcing brain sites and to natural reinforcers. Brain Research. 109: 497-514. PMID 819104 DOI: 10.1016/0006-8993(76)90030-5  0.437
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